articles
- Engineered immunogen binding to alum adjuvant enhances humoral immunity. 26:430-440. 2020
- A highly potent long-acting small-molecule HIV-1 capsid inhibitor with efficacy in a humanized mouse model. 25:1377-1384. 2019
- Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer. 25:628-640. 2019
- High-performance medicine: the convergence of human and artificial intelligence. 25:44-56. 2019
- Looking forward 25 years: the future of medicine. 25:1804-1807. 2019
- Precision epidemiology for infectious disease control. 25:206-211. 2019
- The future of individualized health maintenance. 25:712-714. 2019
- A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein. 24:401-407. 2018
- DPP8/DPP9 inhibitor-induced pyroptosis for treatment of acute myeloid leukemia. 24:1151-1156. 2018
- Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models. 24:194-202. 2018
- Senolytics improve physical function and increase lifespan in old age. 24:1246-+. 2018
- Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing. 23:878-884. 2017
- Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis. 23:1362-1368. 2017
- Omega-3 fatty acid epoxides are autocrine mediators that control the magnitude of IgE-mediated mast cell activation. 23:1287-1297. 2017
- 3K3A-activated protein C stimulates postischemic neuronal repair by human neural stem cells in mice. 22:1050-1055. 2016
- Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice. 22:78-83. 2016
- Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models. 22:1108-1119. 2016
- International AIDS Society global scientific strategy: towards an HIV cure 2016. 22:839-850. 2016
- Retinal lipid and glucose metabolism dictates angiogenesis through the lipid sensor Ffar1. 22:439-445. 2016
- Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth. 23:120-127. 2016
- Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition. 22:262-269. 2016
- PAR1 signaling regulates the retention and recruitment of EPCR-expressing bone marrow hematopoietic stem cells. 21:1307-1317. 2015
- GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease. 20:886-896. 2014
- Translational strategies and challenges in regenerative medicine. 20:814-821. 2014
- A colorectal cancer classification system that associates cellular phenotype and responses to therapy. 19:619-625. 2013
- Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome. 19:473-480. 2013
- Suppressing aberrant GluN3A expression rescues synaptic and behavioral impairments in Huntington's disease models. 19:1030-1038. 2013
- Another HIV vaccine failure: where to next?. 19:1576-1577. 2013
- Coagulation factor defends adenovirus from immune attack. 19:406-7. 2013
- Exploring the epigenetics of cocaine resistance. 19:136-137. 2013
- MSCs: science and trials. 19:812. 2013
- Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy. 19:1039-1046. 2013
- Annotating MYC status with 89-Zr-transferrin imaging. 18:1586-1591. 2012
- MDM4 is a key therapeutic target in cutaneous melanoma. 18:1239-1247. 2012
- Dendritically targeted Bdnf mRNA is essential for energy balance and response to leptin. 18:564-571. 2012
- Neural precursor cells induce cell death of high-grade astrocytomas through stimulation of TRPV1. 18:1232-8. 2012
- Pharmacological targeting of the thrombomodulin-activated protein c pathway mitigates radiation toxicity. 18:1123-9. 2012
- Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway. 18:159-165. 2012
- Tissue factor-protease-activated receptor 2 signaling promotes diet-induced obesity and adipose inflammation. 17:1490-1497. 2011
- Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis. 16:1152-1156. 2010
- Neutrophils release brakes of coagulation. 16:851-852. 2010
- Passive neutralizing antibody controls shiv viremia and enhances b cell responses in infant macaques. 16:1117-1119. 2010
- The TLX1 oncogene drives aneuploidy in T cell transformation. 16:1321-1327. 2010
- Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin. 15:1407-1413. 2009
- CCL3L1 and HIV/AIDS susceptibility. 15:1110-1112. 2009
- Tilting toward immunosuppression. 15:496-497. 2009
- Effective, low-titer antibody protection against low-dose repeated mucosal shiv challenge in macaques. 15:951-954. 2009
- Neutralizing antibodies generated during natural hiv-1 infection: Good news for an hiv-1 vaccine?. 15:866-870. 2009
- Synovial fibroblasts spread rheumatoid arthritis to unaffected joints. 15:1414-20. 2009
- Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge. 14:25-27. 2008
- Expression of a noncoding rna is elevated in alzheimer's disease and drives rapid feed-forward regulation of beta-secretase. 14:723-730. 2008
- Nonhuman primate models and the failure of the merck hiv-1 vaccine in humans. 14:617-621. 2008
- The CREB1 coactivator Crtc1 is required for energy balance and fertility. 14:1112-1117. 2008
- The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak. 14:45-54. 2008
- Stem cells act through multiple mechanisms to benefit mice with neurodegenerative metabolic disease. 13:439-447. 2007
- Broad hiv-1 neutralization mediated by cd4-binding site antibodies. 13:1032-1034. 2007
- Essential role of stromally induced hedgehog signaling in B-cell malignancies. 13:944-951. 2007
- Extralymphatic virus sanctuaries as a consequence of potent T-cell activation. 13:1316-1323. 2007
- Protein carbamylation links inflammation, smoking, uremia and atherogenesis. 13:1176-1184. 2007
- TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity. 13:543-551. 2007
- Hypothalamic huntingtin-associated protein 1 as a mediator of feeding behavior. 12:526-533. 2006
- Side effects may include evolution. 12:890-891. 2006
- A crucial role of mitochondrial Hsp40 in preventing dilated cardiomyopathy. 12:128-132. 2006
- Activated protein C inhibits tissue plasminogen activator-induced brain hemorrhage. 12:1278-1285. 2006
- Channeling pain. 12:506-507. 2006
- Interleukin-10 determines viral clearance or persistence in vivo. 12:1301-1309. 2006
- Quantification of antibody responses against multiple antigens of the two infectious forms of Vaccinia virus provides a benchmark for smallpox vaccination. 12:1310-1315. 2006
- Regulation of osteoclast differentiation and function by the CaMK-CREB pathway. 12:1410-1416. 2006
- Viral nanoparticles as tools for intravital vascular imaging. 12:354-360. 2006
- Platelets mediate cytotoxic T lymphocyte-induced liver damage. 11:1167-1169. 2005
- Molecular pathways to neurodegeneration. 10:S2-S9. 2004
- Sporadic ALS: blame it on the editor. 10:347-347. 2004
- Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling. 10:712-718. 2004
- Regulation of angiogenesis by tissue factor cytoplasmic domain signaling. 10:502-509. 2004
- Role of isg15 protease ubp43 (usp18) in innate immunity to viral infection. 10:1374-1378. 2004
- Tcr affinity and negative regulation limit autoimmunity. 10:1234-1239. 2004
- Tissue plasminogen activator neurovascular toxicity is controlled by activated protein C. 10:1379-1383. 2004
- gp41: HIV's shy protein. 10:133-134. 2004
- Activated protein c blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective. 9:338-342. 2003
- Genetic deficiency in pparg does not alter development of experimental prostate cancer. 9:1265-1266. 2003
- Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to hiv-1 gp120. 9:343-346. 2003
- New helicase-primase inhibitors as drug candidates for the treatment of herpes simplex disease. 8:392-398. 2002
- A DNA vaccine against vegf receptor 2 prevents effective angiogenesis and inhibits tumor growth. 8:1369-1375. 2002
- Bone marrow-derived stem cells target retinal astrocytes and can promote or inhibit retinal angiogenesis. 8:1004-1010. 2002
- Platelets in atherothrombosis. 8:1227-1234. 2002
- The t(8;21) fusion protein, aml1-eto, specifically represses the transcription of the p14(arf) tumor suppressor in acute myeloid leukemia. 8:743-750. 2002
- Is tissue plasminogen activator a threat to neurons?. 7:17-18. 2001
- Differential regulation of antiviral T-cell immunity results in stable CD8(+) but declining CD4(+) T-cell memory. 7:913-919. 2001
- Shakespeare in love - with NMDA receptors?. 5:270-271. 1999
- Integration of endoplasmic reticulum signaling in health and disease. 5:745-751. 1999
- Neuroprotection by a caspase inhibitor in acute bacterial meningitis. 5:298-302. 1999
- Reversal of virus-induced systemic shock and respiratory failure by blockade of the lymphotoxin pathway. 5:1370-1374. 1999
- Tissue plasminogen activator (tPA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice. 4:228-231. 1998
- Activators of the nuclear receptor ppar gamma enhance colon polyp formation. 4:1058-1061. 1998
- Prp expression in b lymphocytes is not required for prion neuroinvasion. 4:1429-1433. 1998
- Janus faces of NF-κB: Neurodestruction versus neuroprotection. 3:20-22. 1997
- Antiviral pressure exerted by hiv-1-specific cytotoxic t lymphocytes (ctls) during primary infection demonstrated by rapid selection of ctl escape virus. 3:205-211. 1997
- Passive immunization with a human monoclonal antibody protects hu-pbl-scid mice against challenge by primary isolates of hiv-1. 3:1389-1393. 1997
- Primary demyelination in transgenic mice expressing interferon-gamma. 3:1037-1041. 1997
- The human 37-kDa laminin receptor precursor interacts with the prion protein in eukaryotic cells. 3:1383-1388. 1997
- A model of measles virus-induced immunosuppression: Enhanced susceptibility of neonatal human pbls. 2:1250-1254. 1996
- The hepatitis B virus persists for decades after patients' recovery from acute viral hepatitis despite active maintenance of a cytotoxic T-lymphocyte response. 2:1104-1108. 1996