recent publications

• academic article

  • Magdeldin, S., Yamamoto, K., Yoshida, Y., Xu, B., Zhang, Y., Fujinaka, H., Yaoita, E., Yates III, J. R., Yamamoto, T. Deep proteome mapping of mouse kidney based on OFFGel prefractionation reveals remarkable protein post- translational modifications Journal of Proteome Research  2014 13:1636-1646  DOI:10.1021/pr401122m  PMID:24495006  PMCID:PMC3993965
  • Hitomi, K., Arvai, A. S., Yamamoto, J., Hitomi, C., Teranishi, M., Hirouchi, T., Yamamoto, K., Iwai, S., Tainer, J. A., Hidema, J., Getzoff, E. D. Eukaryotic class II cyclobutane pyrimidine dimer photolyase structure reveals basis for improved ultraviolet tolerance in plants Journal of Biological Chemistry  2012 287:12060-12069  DOI:10.1074/jbc.M111.244020  PMID:22170053  PMCID:PMC3320952
  • Okafuji, A., Biskup, T., Hitomi, K., Getzoff, E. D., Kaiser, G., Batschauer, A., Bacher, A., Hidema, J., Teranishi, M., Yamamoto, K., Schleicher, E., Weber, S. Light-induced activation of class II cyclobutane pyrimidine dimer photolyases DNA Repair  2010 9:495-505  DOI:10.1016/j.dnarep.2010.01.014  PMID:20227927
  • Yamamoto, K., Kojima, T., Adachi, T., Hayashi, M., Matsushita, T., Takamatsu, J., Loskutoff, D. J., Saito, H. Obesity enhances the induction of plasminogen activator inhibitor-1 by restraint stress: a possible mechanism of stress-induced renal fibrin deposition in obese mice Journal of Thrombosis and Haemostasis  2005 3:1495-1502  DOI:10.1111/j.1538-7836.2005.01399.x  PMID:15978107
  • Takeshita, K., Hayashi, M., Iino, S., Kondo, T., Inden, Y., Iwase, M., Kojima, T., Hirai, M., Ito, M., Loskutoff, D. J., Saito, H., Murohara, T., et al. Increased expression of plasminogen activator inhibitor-1 in cardiomyocytes contributes to cardiac fibrosis after myocardial infarction American Journal of Pathology  2004 164:449-456  DOI:10.1016/s0002-9440(10)63135-5  PMID:14742251  PMCID:PMC1602257
  • Yamamoto, K., Shimokawa, T., Yi, H., Isobe, K., Kojima, T., Loskutoff, D. J., Saito, H. Aging accelerates endotoxin-induced thrombosis: increased responses of plasminogen activator inhibitor-1 and lipopolysaccharide signaling with aging American Journal of Pathology  2002 161:1805-1814  DOI:10.1016/s0002-9440(10)64457-4  PMID:12414527  PMCID:PMC1850766
  • Yamamoto, K., Shimokawa, T., Yi, H., Isobe, K., Kojima, T., Loskutoff, D. J., Saito, H. Aging and obesity augment the stress-induced expression of tissue factor gene in the mouse Blood  2002 100:4011-4018  DOI:10.1182/blood-2002-03-0945  PMID:12393670
  • Takeshita, K., Yamamoto, K., Ito, M., Kondo, T., Matsushita, T., Hirai, M., Kojima, T., Nishimura, M., Nabeshima, Y., Loskutoff, D. J., Saito, H., Murohara, T. Increased expression of plasminogen activator inhibitor-1 with fibrin deposition in a murine model of aging, "klotho" mouse Seminars in Thrombosis and Hemostasis  2002 28:545-553  DOI:10.1055/s-2002-36699  PMID:12536348
  • Yamamoto, K., Takeshita, K., Shimokawa, T., Yi, H., Isobe, K., Loskutoff, D. J., Saito, H. Plasminogen activator inhibitor-1 is a major stress-regulated gene: Implications for stress-induced thrombosis in aged individuals Proceedings of the National Academy of Sciences of the United States of America  2002 99:890-895  DOI:10.1073/pnas.022608799  PMID:11792849  PMCID:PMC117401
  • Yamamoto, K., Loskutoff, D. J. Expression of transforming growth factor-beta and tumor necrosis factor-alpha in the plasma and tissues of mice with lupus nephritis Laboratory Investigation  2000 80:1561-1570  PMID:11045573
  • Yamamoto, K., Shimokawa, T., Kojima, T., Loskutoff, D. J., Saito, H. Regulation of murine protein C gene expression in vivo: effects of tumor necrosis factor-alpha, interleukin-1, and transforming growth factor-beta Thrombosis and Haemostasis  1999 82:1297-1301  PMID:10544917
  • Estelles, A., Gilabert, J., Grancha, S., Yamamoto, K., Thinnes, T., Espana, F., Aznar, J., Loskutoff, D. J. Abnormal expression of type 1 plasminogen activator inhibitor and tissue factor in severe preeclampsia Thrombosis and Haemostasis  1998 79:500-508  PMID:9580327
  • Yamamoto, K., Loskutoff, D. J. Extrahepatic expression and regulation of protein C in the mouse American Journal of Pathology  1998 153:547-555  DOI:10.1016/s0002-9440(10)65597-6  PMID:9708814  PMCID:PMC1852986
  • Yamamoto, K., Loskutoff, D. J., Saito, H. Renal expression of fibrinolytic genes and tissue factor in a murine model of renal disease as a function of age Seminars in Thrombosis and Hemostasis  1998 24:261-268  DOI:10.1055/s-2007-995852  PMID:9701458
  • Yamamoto, K., de Waard, V., Fearns, C., Loskutoff, D. J. Tissue distribution and regulation of murine von Willebrand factor gene expression in vivo Blood  1998 92:2791-2801  PMID:9763564
  • Samad, F., Yamamoto, K., Pandey, M., Loskutoff, D. J. Elevated expression of transforming growth factor-beta in adipose tissue from obese mice Molecular Medicine  1997 3:37-48  PMID:9132278  PMCID:PMC2230108
  • Yamamoto, K., Loskutoff, D. J. The kidneys of mice with autoimmune disease acquire a hypofibrinolytic/procoagulant state that correlates with the development of glomerulonephritis and tissue microthrombosis American Journal of Pathology  1997 151:725-734  PMID:9284821  PMCID:PMC1857842
  • Samad, F., Yamamoto, K., Loskutoff, D. J. Distribution and regulation of plasminogen activator inhibitor-1 in murine adipose tissue in vivo. Induction by tumor necrosis factor-alpha and lipopolysaccharide Journal of Clinical Investigation  1996 97:37-46  DOI:10.1172/jci118404  PMID:8550848  PMCID:PMC507060
  • Yamamoto, K., Loskutoff, D. J. Fibrin deposition in tissues from endotoxin-treated mice correlates with decreases in the expression of urokinase-type but not tissue-type plasminogen activator Journal of Clinical Investigation  1996 97:2440-2451  DOI:10.1172/jci118691  PMID:8647936  PMCID:PMC507329