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Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation

Academic Article
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Overview

related to degree

  • Marciano, David, Ph.D. in Biology, Scripps Research 2010 - 2014

authors

  • Choi, J. H.
  • Banks, A. S.
  • Kamenecka, Theodore
  • Busby, S. A.
  • Chalmers, Michael
  • Kumar, N.
  • Kuruvilla, D. S.
  • Shin, Y. S.
  • He, Y.
  • Bruning, John
  • Marciano, David
  • Cameron, Michael
  • Laznik, D.
  • Jurczak, M. J.
  • Schurer, S. C.
  • Vidovic, D.
  • Shulman, G. I.
  • Spiegelman, B. M.
  • Griffin, Patrick

publication date

  • 2011

journal

  • Nature  Journal

subject areas

  • 3T3-L1 Cells
  • Adipocytes
  • Adipose Tissue, White
  • Animals
  • Biphenyl Compounds
  • Body Fluids
  • COS Cells
  • Cercopithecus aethiops
  • Cyclin-Dependent Kinase 5
  • Dietary Fats
  • Disease Models, Animal
  • Dose-Response Relationship, Drug
  • HEK293 Cells
  • Humans
  • Hypoglycemic Agents
  • Ligands
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Mice, Obese
  • Models, Molecular
  • Obesity
  • Osteogenesis
  • PPAR gamma
  • Phosphorylation
  • Phosphoserine
  • Thiazolidinediones
  • Transcription, Genetic
  • Tumor Necrosis Factor-alpha
  • Weight Gain
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Identity

PubMed Central ID

  • PMC3179551

International Standard Serial Number (ISSN)

  • 0028-0836

Digital Object Identifier (DOI)

  • 10.1038/nature10383

PubMed ID

  • 21892191
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Additional Document Info

start page

  • 477

end page

  • 481

volume

  • 477

issue

  • 7365

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