recent publications

• academic article

  • Sankaran, B., Bonnett, S. A., Shah, K., Gabriel, S., Reddy, R., Schimmel, P., Rodionov, D. A., de Crecy-Lagard, V., Helmann, J. D., Iwata-Reuyl, D., Swairjo, M. A. Zinc-independent folate biosynthesis: genetic, biochemical, and structural investigations reveal new metal dependence for GTP cyclohydrolase IB Journal of Bacteriology  2009 191:6936-6949  DOI:10.1128/jb.00287-09  PMID:19767425  PMCID:PMC2772490
  • El Yacoubi, B., Lyons, B., Cruz, Y., Reddy, R., Nordin, B., Agnelli, F., Williamson, J. R., Schimmel, P., Swairjo, M. A., de Crecy-Lagard, V. The universal YrdC/Sua5 family is required for the formation of threonylcarbamoyladenosine in tRNA Nucleic Acids Research  2009 37:2894-2909  DOI:10.1093/nar/gkp152  PMID:19287007  PMCID:PMC2685093
  • Bacher, J. A., Waas, W. F., Metzgar, D., de Crecy-Lagard, V., Schimmel, P. Genetic code ambiguity confers a selective advantage on Acinetobacter baylyi Journal of Bacteriology  2007 189:6494-6496  DOI:10.1128/jb.00622-07  PMID:17616603  PMCID:PMC1951902
  • Waas, W. F., de Crecy-Lagard, V., Schimmel, P. Discovery of a gene family critical to wyosine base formation in a subset of phenylalanine-specific transfer RNAs Journal of Biological Chemistry  2005 280:37616-37622  DOI:10.1074/jbc.M506939200  PMID:16162496
  • Swairjo, M. A., Reddy, R. R., Lee, B., Van Lanen, S. G., Brown, S., de Crecy-Lagard, V., Iwata-Reuyl, D., Schimmel, P. Crystallization and preliminary X-ray characterization of the nitrile reductase QueF: a queuosine-biosynthesis enzyme Acta Crystallographica Section F-Structural Biology and Crystallization Communications  2005 61:945-948  DOI:10.1107/s1744309105029246  PMID:16511203  PMCID:PMC1991305
  • Reader, J. S., Ordoukhanian, P. T., Kim, J. G., de Crecy-Lagard, V., Hwang, I., Farrand, S., Schimmel, P. Major biocontrol of plant tumors targets tRNA synthetase Science  2005 309:1533  DOI:10.1126/science.1116841  PMID:16141066
  • Cirz, R. T., Chin, J. K., Andes, D. R., de Crecy-Lagard, V., Craig, W. A., Romesberg, F. E. Inhibition of mutation and combating the evolution of antibiotic resistance PLoS Biology  2005 3:1024-1033  DOI:10.1371/journal.pbio.0030176  PMID:15869329  PMCID:PMC1088971
  • Bacher, J. M., de Crecy-Lagard, V., Schimmel, P. R. Inhibited cell growth and protein functional changes from an editing-defective tRNA synthetase Proceedings of the National Academy of Sciences of the United States of America  2005 102:1697-1701  DOI:10.1073/pnas.0409064102  PMID:15647356  PMCID:PMC547871
  • Pezo, V., Metzgar, D., Hendrickson, T. L., Waas, W. F., Hazebrouck, S., Doring, V., Marliere, P., Schimmel, P., de Crecy-Lagard, V. Artificially ambiguous genetic code confers growth yield advantage Proceedings of the National Academy of Sciences of the United States of America  2004 101:8593-8597  DOI:10.1073/pnas.0402893101  PMID:15163798  PMCID:PMC423239
  • Reader, J. S., Metzgar, D., Schimmel, P., de Crecy-Lagard, V. Identification of four genes necessary for biosynthesis of the modified nucleoside queuosine Journal of Biological Chemistry  2004 279:6280-6285  DOI:10.1074/jbc.M310858200  PMID:14660578
  • Metzgar, D., Bacher, J. M., Pezo, V., Reader, J., Doring, V., Schimmel, P., Marliere, P., de Crecy-Lagard, V. Acinetobacter sp. ADP1: an ideal model organism for genetic analysis and genome engineering Nucleic Acids Research  2004 32:5780-5790  DOI:10.1093/nar/gkh881  PMID:15514111  PMCID:PMC528786
  • Hendrickson, T. L., de Crecy-Lagard, V., Schimmel, P. Incorporation of nonnatural amino acids into proteins Annual Review of Biochemistry  2004 73:147-176  DOI:10.1146/annurev.biochem.73.012803.092429  PMID:15189139
  • Bishop, A. C., Xu, J. M., Johnson, R. C., Schimmel, P., de Crecy-Lagard, V. Identification of the tRNA-dihydrouridine synthase family Journal of Biological Chemistry  2002 277:25090-25095  DOI:10.1074/jbc.M203208200  PMID:11983710
  • Hendrickson, T. L., Nomanbhoy, T. K., de Crecy-Lagard, V., Fukai, S., Nureki, O., Yokoyama, S., Schimmel, P. Mutational separation of two pathways for editing by a class I tRNA synthetase Molecular Cell  2002 9:353-362  DOI:10.1016/s1097-2765(02)00449-5  PMID:11864608
  • Fabrega, C., Farrow, M. A., Mukhopadhyay, B., de Crecy-Lagard, V., Ortiz, A. R., Schimmel, P. An aminoacyl tRNA synthetase whose sequence fits into neither of the two known classes Nature  2001 411:110-114  DOI:10.1038/35075121  PMID:11333988
  • Doring, V., Mootz, H. D., Nangle, L. A., Hendrickson, T. L., de Crecy-Lagard, V., Schimmel, P., Marliere, P. Enlarging the amino acid set of Escherichia coli by infiltration of the valine coding pathway Science  2001 292:501-504  DOI:10.1126/science.1057718  PMID:11313495