recent publications

• academic article

  • Pugach, P., Ozorowski, G., Cupo, A., Ringe, R., Yasmeen, A., de Val, N., Derking, R., Kim, H. J., Korzun, J., Golabek, M., de los Reyes, K., Ketas, T. J., et al. A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene Journal of Virology  2015 89:3380-3395  DOI:10.1128/jvi.03473-14  PMID:25589637  PMCID:PMC4337520
  • Lee, J. H., Leaman, D. P., Kim, A. S., Torrents de la Peña, A., Sliepen, K., Yasmeen, A., Derking, R., Ramos, A., de Taeye, S. W., Ozorowski, G., Klein, F., Burton, D. R., et al. Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike Nature Communications  2015 6:8167  DOI:10.1038/ncomms9167  PMID:26404402  PMCID:PMC4586043
  • Guttman, M., Cupo, A., Julien, J. P., Sanders, R. W., Wilson, I. A., Moore, J. P., Lee, K. K. Antibody potency relates to the ability to recognize the closed, pre-fusion form of HIV Env Nature Communications  2015 6:6144  DOI:10.1038/ncomms7144  PMID:25652336  PMCID:PMC4338595
  • Derking, R., Ozorowski, G., Sliepen, K., Yasmeen, A., Cupo, A., Torres, J. L., Julien, J. P., Lee, J. H., van Montfort, T., de Taeye, S. W., Connors, M., Burton, D. R., et al. Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer PLoS Pathogens  2015 11:e1004767  DOI:10.1371/journal.ppat.1004767  PMID:25807248  PMCID:PMC4373910
  • Julien, J. P., Lee, J. H., Ozorowski, G., Hua, Y., Torrents de la Peña, A., de Taeye, S. W., Nieusma, T., Cupo, A., Yasmeen, A., Golabek, M., Pugach, P., Klasse, P. J., et al. Design and structure of two HIV-1 clade C SOSIP.664 trimers that increase the arsenal of native-like Env immunogens Proceedings of the National Academy of Sciences of the United States of America  2015 112:11947-11952  DOI:10.1073/pnas.1507793112  PMID:26372963  PMCID:PMC4586835
  • Sanders, R. W., van Gils, M. J., Derking, R., Sok, D., Ketas, T. J., Burger, J. A., Ozorowski, G., Cupo, A., Simonich, C., Goo, L., Arendt, H., Kim, H. J., et al. HIV-1 neutralizing antibodies induced by native-like envelope trimers Science  2015 349:aac4223  DOI:10.1126/science.aac4223  PMID:26089353  PMCID:PMC4498988
  • Dosenovic, P., von Boehmer, L., Escolano, A., Jardine, J., Freund, N. T., Gitlin, A. D., McGuire, A. T., Kulp, D. W., Oliveira, T., Scharf, L., Pietzsch, J., Gray, M. D., et al. Immunization for HIV-1 broadly neutralizing antibodies in human Ig knockin mice Cell  2015 161:1505-1515  DOI:10.1016/j.cell.2015.06.003  PMID:26091035  PMCID:PMC4604566
  • Hu, J. K., Crampton, J. C., Cupo, A., Ketas, T., van Gils, M. J., Sliepen, K., de Taeye, S. W., Sok, D., Ozorowski, G., Deresa, I., Stanfield, R., Ward, A. B., et al. Murine antibody responses to cleaved soluble HIV-1 envelope trimers are highly restricted in specificity Journal of Virology  2015 89:10383-10398  DOI:10.1128/jvi.01653-15  PMID:26246566  PMCID:PMC4580201
  • Sliepen, K., Ozorowski, G., Burger, J. A., van Montfort, T., Stunnenberg, M., LaBranche, C., Montefiori, D. C., Moore, J. P., Ward, A. B., Sanders, R. W. Presenting native-like HIV-1 envelope trimers on ferritin nanoparticles improves their immunogenicity Retrovirology  2015 12:82  DOI:10.1186/s12977-015-0210-4  PMID:26410741  PMCID:PMC4583754
  • Pritchard, L. K., Vasiljevic, S., Ozorowski, G., Seabright, G. E., Cupo, A., Ringe, R., Kim, H. J., Sanders, R. W., Doores, K. J., Burton, D. R., Wilson, I. A., Ward, A. B., et al. Structural constraints determine the glycosylation of HIV-1 envelope trimers Cell Reports  2015 11:1604-1613  DOI:10.1016/j.celrep.2015.05.017  PMID:26051934  PMCID:PMC4555872
  • Falkowska, E., Le, K. M., Ramos, A., Doores, K. J., Lee, J. H., Blattner, C., Ramirez, A., Derking, R., van Gils, M. J., Liang, C. H., McBride, R., von Bredow, B., et al. Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers Immunity  2014 40:657-668  DOI:10.1016/j.immuni.2014.04.009  PMID:24768347  PMCID:PMC4070425
  • Guttman, M., Garcia, N. K., Cupo, A., Matsui, T., Julien, J. P., Sanders, R. W., Wilson, I. A., Moore, J. P., Lee, K. K. CD4-induced activation in a soluble HIV-1 Env trimer Structure  2014 22:974-984  DOI:10.1016/j.str.2014.05.001  PMID:24931470  PMCID:PMC4231881
  • Doria-Rose, N. A., Schramm, C. A., Gorman, J., Moore, P. L., Bhiman, J. N., DeKosky, B. J., Ernandes, M. J., Georgiev, I. S., Kim, H. J., Pancera, M., Staupe, R. P., Altae-Tran, H. R., et al. Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies Nature  2014 509:55-62  DOI:10.1038/nature13036  PMID:24590074  PMCID:PMC4395007
  • Yasmeen, A., Ringe, R., Derking, R., Cupo, A., Julien, J. P., Burton, D. R., Ward, A. B., Wilson, I. A., Sanders, R. W., Moore, J. P., Klasse, P. J. Differential binding of neutralizing and non-neutralizing antibodies to native-like soluble HIV-1 Env trimers, uncleaved Env proteins, and monomeric subunits Retrovirology  2014 11:41  DOI:10.1186/1742-4690-11-41  PMID:24884783  PMCID:PMC4067080
  • Sok, D., van Gils, M. J., Pauthner, M., Julien, J. P., Saye-Francisco, K. L., Hsueh, J., Briney, B., Lee, J. H., Le, K. M., Lee, P. S., Hua, Y., Seaman, M. S., et al. Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex Proceedings of the National Academy of Sciences of the United States of America  2014 111:17624-17629  DOI:10.1073/pnas.1415789111  PMID:25422458  PMCID:PMC4267403
  • Chung, N. P. Y., Matthews, K., Kim, H. J., Ketas, T. J., Golabek, M., de los Reyes, K., Korzun, J., Yasmeen, A., Sanders, R. W., Klasse, P. J., Wilson, I. A., Ward, A. B., et al. Stable 293 T and CHO cell lines expressing cleaved, stable HIV-1 envelope glycoprotein trimers for structural and vaccine studies Retrovirology  2014 11:33  DOI:10.1186/1742-4690-11-33  PMID:24767177  PMCID:PMC4032163
  • Blattner, C., Lee, J. H., Sliepen, K., Derking, R., Falkowska, E., de la Pena, A. T., Cupo, A., Julien, J. P., van Gils, M., Lee, P. S., Peng, W., Paulson, J. C., et al. Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers Immunity  2014 40:669-680  DOI:10.1016/j.immuni.2014.04.008  PMID:24768348  PMCID:PMC4057017
  • Garces, F., Sok, D., Kong, L., McBride, R., Kim, H. J., Saye-Francisco, K. F., Julien, J. P., Hua, Y., Cupo, A., Moore, J. P., Paulson, J. C., Ward, A. B., et al. Structural evolution of glycan recognition by a family of potent HIV antibodies Cell  2014 159:69-79  DOI:10.1016/j.cell.2014.09.009  PMID:25259921  PMCID:PMC4278586
  • Murin, C. D., Julien, J. P., Sok, D., Stanfield, R. L., Khayat, R., Cupo, A., Moore, J. P., Burton, D. R., Wilson, I. A., Ward, A. B. Structure of 2G12 Fab2 in complex with soluble and fully glycosylated HIV-1 Env by negative-stain single-particle electron microscopy Journal of Virology  2014 88:10177-10188  DOI:10.1128/jvi.01229-14  PMID:24965454  PMCID:PMC4136306
  • Sanders, R. W., Derking, R., Cupo, A., Julien, J. P., Yasmeen, A., de Val, N., Kim, H. J., Blattner, C., de la Pena, A. T., Korzun, J., Golabek, M., de los Reyes, K., et al. A next-generation cleaved, soluble HIV-1 Env Trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies PLoS Pathogens  2013 9:e1003618  DOI:10.1371/journal.ppat.1003618  PMID:24068931  PMCID:PMC3777863
  • Isik, G., Chung, N. P. Y., van Montfort, T., Menis, S., Matthews, K., Schief, W. R., Moore, J. P., Sanders, R. W. An HIV-1 envelope glycoprotein trimer with an embedded IL-21 domain activates human B cells PLoS One  2013 8:e67309  DOI:10.1371/journal.pone.0067309  PMID:23826263  PMCID:PMC3691133
  • McMichael, A., Picker, L. J., Moore, J. P., Burton, D. R. Another HIV vaccine failure: where to next? Nature Medicine  2013 19:1576-1577  DOI:10.1038/nm.3413  PMID:24309655
  • Julien, J. P., Lee, J. H., Cupo, A., Murin, C. D., Derking, R., Hoffenberg, S., Caulfield, M. J., King, C. R., Marozsan, A. J., Klasse, P. J., Sanders, R. W., Moore, J. P., et al. Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9 Proceedings of the National Academy of Sciences of the United States of America  2013 110:213-218  DOI:10.1073/pnas.1217537110  PMID:23426631  PMCID:PMC3600498
  • Julien, J. P., Sok, D., Khayat, R., Lee, J. H., Doores, K. J., Walker, L. M., Ramos, A., Diwanji, D. C., Pejchal, R., Cupo, A., Katpally, U., Depetris, R. S., et al. Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans PLoS Pathogens  2013 9:e1003342  DOI:10.1371/journal.ppat.1003342  PMID:23658524  PMCID:PMC3642082
  • Ringe, R. P., Sanders, R. W., Yasmeen, A., Kim, H. J., Lee, J. H., Cupo, A., Korzun, J., Derking, R., van Montfort, T., Julien, J. P., Wilson, I. A., Klasse, P. J., et al. Cleavage strongly influences whether soluble HIV-1 envelope glycoprotein trimers adopt a native-like conformation Proceedings of the National Academy of Sciences of the United States of America  2013 110:18256-18261  DOI:10.1073/pnas.1314351110  PMID:24145402  PMCID:PMC3831437
  • Lyumkis, D., Julien, J. P., de Val, N., Cupo, A., Potter, C. S., Klasse, P. J., Burton, D. R., Sanders, R. W., Moore, J. P., Carragher, B., Wilson, I. A., Ward, A. B. Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer Science  2013 342:1484-1490  DOI:10.1126/science.1245627  PMID:24179160  PMCID:PMC3954647
  • Julien, J. P., Cupo, A., Sok, D., Stanfield, R. L., Lyumkis, D., Deller, M. C., Klasse, P. J., Burton, D. R., Sanders, R. W., Moore, J. P., Ward, A. B., Wilson, I. A. Crystal structure of a soluble cleaved HIV-1 envelope trimer Science  2013 342:1477-1483  DOI:10.1126/science.1245625  PMID:24179159  PMCID:PMC3886632
  • Klasse, P. J., Depetris, R. S., Pejchal, R., Julien, J. P., Khayat, R., Lee, J. H., Marozsan, A. J., Cupo, A., Cocco, N., Korzun, J., Yasmeen, A., Ward, A. B., et al. Influences on Trimerization and Aggregation of Soluble, Cleaved HIV-1 SOSIP Envelope Glycoprotein Journal of Virology  2013 87:9873-9885  DOI:10.1128/jvi.01226-13  PMID:23824824  PMCID:PMC3754145
  • Khayat, R., Lee, J. H., Julien, J. P., Cupo, A., Klasse, P. J., Sanders, R. W., Moore, J. P., Wilson, I. A., Ward, A. B. Structural characterization of cleaved, soluble HIV-1 envelope glycoprotein trimers Journal of Virology  2013 87:9865-9872  DOI:10.1128/jvi.01222-13  PMID:23824817  PMCID:PMC3754114
  • Kong, L., Lee, J. H., Doores, K. J., Murin, C. D., Julien, J. P., McBride, R., Liu, Y., Marozsan, A., Cupo, A., Klasse, P. J., Hoffenberg, S., Caulfield, M., et al. Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120 Nature Structural & Molecular Biology  2013 20:796-803  DOI:10.1038/nsmb.2594  PMID:23708606  PMCID:PMC3823233
  • Depetris, R. S., Julien, J. P., Khayat, R., Lee, J. H., Pejchal, R., Katpally, U., Cocco, N., Kachare, M., Massi, E., David, K. B., Cupo, A., Marozsan, A. J., et al. Partial enzymatic deglycosylation preserves the structure of cleaved recombinant HIV-1 envelope glycoprotein trimers Journal of Biological Chemistry  2012 287:24239-24254  DOI:10.1074/jbc.M112.371898  PMID:22645128  PMCID:PMC3397850
  • Van Montfort, T., Melchers, M., Isik, G., Menis, S., Huang, P. S., Matthews, K., Michael, E., Berkhout, B., Schief, W. R., Moore, J. P., Sanders, R. W. A chimeric hiv-1 envelope glycoprotein trimer with an embedded granulocyte-macrophage colony-stimulating factor (gm-csf) domain induces enhanced antibody and t cell responses Journal of Biological Chemistry  2011 286:22250-22261  DOI:10.1074/jbc.M111.229625  PMID:21515681  PMCID:PMC3121371
  • Pejchal, R., Doores, K. J., Walker, L. M., Khayat, R., Huang, P. S., Wang, S. K., Stanfield, R. L., Julien, J. P., Ramos, A., Crispin, M., Depetris, R., Katpally, U., et al. A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield Science  2011 334:1097-1103  DOI:10.1126/science.1213256  PMID:21998254  PMCID:PMC3280215
  • Burton, D. R., Hessell, A. J., Keele, B. F., Klasse, P. J., Ketas, T. A., Moldt, B., Dunlop, D. C., Poignard, P., Doyle, L. A., Cavacini, L., Veazey, R. S., Moore, J. P. Limited or no protection by weakly or nonneutralizing antibodies against vaginal shiv challenge of macaques compared with a strongly neutralizing antibody Proceedings of the National Academy of Sciences of the United States of America  2011 108:11181-11186  DOI:10.1073/pnas.1103012108  PMID:21690411  PMCID:PMC3131343
  • Harris, A., Borgnia, M. J., Shi, D., Bartesaghi, A., He, H. F., Pejchal, R., Kang, Y., Depetris, R., Marozsan, A. J., Sanders, R. W., Klasse, P. J., Milne, J. L. S., et al. Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures Proceedings of the National Academy of Sciences of the United States of America  2011 108:11440-11445  DOI:10.1073/pnas.1101414108  PMID:21709254  PMCID:PMC3136299
  • Watkins, D. I., Burton, D. R., Kallas, E. G., Moore, J. P., Koff, W. C. Nonhuman primate models and the failure of the merck hiv-1 vaccine in humans Nature Medicine  2008 14:617-621  DOI:10.1038/nm.f.1759  PMID:18535579  PMCID:PMC3697853
  • Grant, R. M., Hamer, D., Hope, T., Johnston, R., Lange, J., Lederman, M. M., Lieberman, J., Miller, C. J., Moore, J. P., Mosier, D. E., Richman, D. D., Schooley, R. T., et al. Whither or wither microbicides? Science  2008 321:532-534  DOI:10.1126/science.1160355  PMID:18653884  PMCID:PMC2835691
  • Gorry, P. R., Dunfee, R. L., Mefford, M. E., Kunstman, K., Morgan, T., Moore, J. P., Mascola, J. R., Agopian, K., Holm, G. H., Mehle, A., Taylor, J., Farzan, M., et al. Changes in the V3 region of gp 120 contribute to unusually broad coreceptor usage of an HIV-1 isolate from a CCR5 Delta 32 heterozygote Virology  2007 362:163-178  DOI:10.1016/j.virol.2006.11.025  PMID:17239419  PMCID:PMC1973138
  • Kuhmann, S. E., Pugach, P., Kunstman, K. J., Taylor, J., Stanfield, R. L., Snyder, A., Strizki, J. M., Riley, J., Baroudy, B. M., Wilson, I. A., Korber, B. T., Wolinsky, S. M., et al. Genetic and phenotypic analyses of human immunodeficiency virus type 1 escape from a small-molecule ccr5 inhibitor Journal of Virology  2004 78:2790-2807  DOI:10.1128/jvi.78.6.2790-2807.2004  PMID:14990699
  • Herrera, C., Spenlehauer, C., Fung, M. S., Burton, D. R., Beddows, S., Moore, J. P. Nonneutralizing antibodies to the cd4-binding site on the gp120 subunit of human immunodeficiency virus type 1 do not interfere with the activity of a neutralizing antibody against the same site Journal of Virology  2003 77:1084-1091  DOI:10.1128/jvi.77.2.1084-1091.2003  PMID:12502824
  • Veazey, R. S., Shattock, R. J., Pope, M., Kirijan, J. C., Jones, J., Hu, Q. X., Ketas, T., Marx, P. A., Klasse, P. J., Burton, D. R., Moore, J. P. Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to hiv-1 gp120 Nature Medicine  2003 9:343-346  DOI:10.1038/nm833  PMID:12579198
  • Binley, J. M., Sanders, R. W., Master, A., Cayanan, C. S., Wiley, C. L., Schiffner, L., Travis, B., Kuhmann, S., Burton, D. R., Hu, S. L., Olson, W. C., Moore, J. P. Enhancing the proteolytic maturation of human immunodeficiency virus type 1 envelope glycoproteins Journal of Virology  2002 76:2606-2616  DOI:10.1128/jvi.76.6.2606-2616.2002  PMID:11861826
  • Gorry, P. R., Taylor, J., Holm, G. H., Mehle, A., Morgan, T., Cayabyab, M., Farzan, M., Wang, H., Bell, J. E., Kunstman, K., Moore, J. P., Wolinsky, S. M., et al. Increased CCR5 affinity and reduced CCR5/CD4 dependence of a neurovirulent primary human immunodeficiency virus type 1 isolate Journal of Virology  2002 76:6277-6292  DOI:10.1128/jvi.76.12.6277-6292.2002  PMID:12021361
  • Parren, Pwhi, Marx, P. A., Hessell, A. J., Luckay, A., Harouse, J., Cheng-Mayer, C., Moore, J. P., Burton, D. R. Antibody protects macaques against vaginal challenge with a pathogenic r5 simian/human immunodeficiency virus at serum levels giving complete neutralization in vitro Journal of Virology  2001 75:8340-8347  DOI:10.1128/jvi.75.17.8340-8347.2001  PMID:11483779
  • Zwick, M. B., Labrijn, A. F., Wang, M., Spenlehauer, C., Saphire, E. O., Binley, J. M., Moore, J. P., Stiegler, G., Katinger, H., Burton, D. R., Parren, P. W. Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41 Journal of Virology  2001 75:10892-10905  DOI:10.1128/jvi.75.22.10892-10905.2001  PMID:11602729  PMCID:PMC114669
  • Moore, J. P., Parren, Pwhi, Burton, D. R. Genetic subtypes, humoral immunity, and human immunodeficiency virus type 1 vaccine development Journal of Virology  2001 75:5721-5729  DOI:10.1128/jvi.75.13.5721-5729.2001  PMID:11390574
  • Parren, Pwhi, Moore, J. P., Burton, D. R., Sattentau, Q. J. The neutralizing antibody response to hiv-1: Viral evasion and escape from humoral immunity AIDS  1999 13:S137-S162  PMID:10885772
  • Binley, J. M., Wyatt, R., Desjardins, E., Kwong, P. D., Hendrickson, W., Moore, J. P., Sodroski, J. Analysis of the interaction of antibodies with a conserved, enzymatically deglycosylated core of the hiv type 1 envelope glycoprotein 120 AIDS Research and Human Retroviruses  1998 14:191-198  DOI:10.1089/aid.1998.14.191  PMID:9491908
  • Parren, Pwhi, Wang, M., Trkola, A., Binley, J. M., Purtscher, M., Katinger, H., Moore, J. P., Burton, D. R. Antibody neutralization-resistant primary isolates of human immunodeficiency virus type 1 Journal of Virology  1998 72:10270-10274  PMID:9811774  PMCID:PMC110612
  • Mo, H. M., Stamatatos, L., Ip, J. E., Barbas, C. F., Parren, Pwhi, Burton, D. R., Moore, J. P., Ho, D. D. Human immunodeficiency virus type 1 mutants that escape neutralization by human monoclonal antibody igg1b12 Journal of Virology  1997 71:6869-6874  PMID:9261412  PMCID:PMC191968
  • Ditzel, H. J., Parren, Pwhi, Binley, J. M., Sodroski, J., Moore, J. P., Barbas, C. F., Burton, D. R. Mapping the protein surface of human immunodeficiency virus type 1 gp120 using human monoclonal antibodies from phage display libraries Journal of Molecular Biology  1997 267:684-695  DOI:10.1006/jmbi.1997.0912  PMID:9126846
  • Poignard, P., Fouts, T., Naniche, D., Moore, J. P., Sattentau, Q. J. Neutralizing antibodies to human immunodeficiency virus type-1 gp120 induce envelope glycoprotein subunit dissociation Journal of Experimental Medicine  1996 183:473-484  DOI:10.1084/jem.183.2.473  PMID:8627160
  • Trkola, A., Pomales, A. B., Yuan, H., Korber, B., Maddon, P. J., Allaway, G. P., Katinger, H., Barbas, C. F., Burton, D. R., Ho, D. D., Moore, J. P. Cross-clade neutralization of primary isolates of human immunodeficiency virus type 1 by human monoclonal antibodies and tetrameric CD4-IgG Journal of Virology  1995 69:6609-6617  PMID:7474069  PMCID:PMC189569
  • Ditzel, H. J., Binley, J. M., Moore, J. P., Sodroski, J., Sullivan, N., Sawyer, L. S. W., Hendry, R. M., Yang, W. P., Barbas, C. F., Burton, D. R. Neutralizing recombinant human-antibodies to a conformational v2-binding and cd4-binding site-sensitive epitope of hiv-1 gp120 isolated by using an epitope-masking procedure Journal of Immunology  1995 154:893-906  PMID:7529290
  • Moore, J. P., Cao, Y. Z., Qing, L., Sattentau, Q. J., Pyati, J., Koduri, R., Robinson, J., Barbas, C. F., Burton, D. R., Ho, D. D. Primary isolates of human-immunodeficiency-virus type-1 are relatively resistant to neutralization by monoclonal-antibodies to gp120, and their neutralization is not predicted by studies with monomeric gp120 Journal of Virology  1995 69:101-109  PMID:7527081  PMCID:PMC188553
  • Burton, D. R., Pyati, J., Koduri, R., Sharp, S. J., Thornton, G. B., Parren, Pwhi, Sawyer, L. S. W., Hendry, R. M., Dunlop, N., Nara, P. L., Lamacchia, M., Garratty, E., et al. Efficient neutralization of primary isolates of hiv-1 by a recombinant human monoclonal-antibody Science  1994 266:1024-1027  DOI:10.1126/science.7973652  PMID:7973652
  • Moore, J. P., Sattentau, Q. J., Wyatt, R., Sodroski, J. Probing the structure of the human-immunodeficiency-virus surface glycoprotein gp120 with a panel of monoclonal-antibodies Journal of Virology  1994 68:469-484  PMID:7504741  PMCID:PMC236308
  • Roben, P., Moore, J. P., Thali, M., Sodroski, J., Barbas, C. F., Burton, D. R. Recognition properties of a panel of human recombinant fab fragments to the cd4 binding-site of gp120 that show differing abilities to neutralize human-immunodeficiency-virus type-1 Journal of Virology  1994 68:4821-4828  PMID:7518527  PMCID:PMC236421
  • Moore, J. P., Cao, Y. Z., Conley, A. J., Wyatt, R., Robinson, J., Gorny, M. K., Zollapazner, S., Ho, D. D., Koup, R. A. Studies with monoclonal antibodies to the V3 region of HIV-1 gp120 reveal limitations to the utility of solid-phase peptide binding assays Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology  1994 7:332-339  PMID:7510807
  • Sattentau, Q. J., Moore, J. P., Vignaux, F., Traincard, F., Poignard, P. Conformational changes induced in the envelope glycoproteins of the human and simian immunodeficiency viruses by soluble receptor binding Journal of Virology  1993 67:7383-7393  PMID:7693970  PMCID:PMC238202