Journal of Molecular Biology

articles

A molecular target for an alcohol chain-length cutoff. 431:196-209. 2019
Fluorescent trimeric hemagglutinins reveal multivalent receptor binding properties. 431:842-856. 2019
Protein and glycan mimicry in HIV vaccine design. 431:2223-2247. 2019
SARAF luminal domain structure reveals a novel domain-swapped β-sandwich fold important for SOCE modulation. 431:2869-2883. 2019
A novel polar core and weakly fixed C-tail in squid arrestin provide new insight into interaction with rhodopsin. 430:4102-4118. 2018
A proteomic variant approach (ProVarA) for personalized medicine of inherited and somatic disease. 430:2951-2973. 2018
A sortase a programmable phage display format for improved panning of Fab antibody libraries. 430:4387-4400. 2018
A survey of DDX21 activity during Rev/RRE complex formation. 430:537-553. 2018
Effect of tRNA on the maturation of HIV-1 reverse transcriptase. 430:1891-1900. 2018
Expanding the Paradigm: Intrinsically Disordered Proteins and Allosteric Regulation. 430:2309-2320. 2018
From atoms to cells: using mesoscale landscapes to construct visual narratives. 430:3954-3968. 2018
Molecular illustration in research and education: past, present, and future. 430:3969-3981. 2018
Perspectives on structural molecular biology visualization: from past to present. 430:3997-4012. 2018
Revised crystal structure of human adenovirus reveals the limits on protein IX quasi-equivalence and on analyzing large macromolecular complexes. 430:4132-4141. 2018
A DEAD-box helicase mediates an RNA structural transition in the HIV-1 Rev response element. 429:697-714. 2017
A perspective on the structural and functional constraints for immune evasion: insights from influenza virus. 429:2694-2709. 2017
Architecture of the flagellar switch complex of Escherichia coli: conformational plasticity of FliG and implications for adaptive remodeling. 429:1305-1320. 2017
Backbone engineering within a latent β-hairpin structure to design inhibitors of polyglutamine amyloid formation. 429:308-323. 2017
Marking the milestones in structural biology. 429:2591-2593. 2017
Mining naive rabbit antibody repertoires by phage display for monoclonal antibodies of therapeutic utility. 429:2954-2973. 2017
Nucleotide binding to ARL2 in the TBCD∙ARL2∙β-tubulin complex drives conformational changes in β-tubulin. 429:3696-3716. 2017
Structural foundations of RNA silencing by Argonaute. 429:2619-2639. 2017
The role of hexon protein as a molecular mold in patterning the protein IX organization in human adenoviruses. 429:2747-2751. 2017
A substrate mimic allows high-throughput assay of the FabA protein and consequently the identification of a novel inhibitor of pseudomonas aeruginosa FabA. 428:108-120. 2016
Challenges in structural approaches to cell modeling. 428:2943-2964. 2016
DIx5 homeodomain:DNA complex: structure, binding and effect of mutations related to split hand and foot malformation syndrome. 428:1130-1141. 2016
Deciphering complexity in molecular biophysics with single-molecule resolution. 428:301-307. 2016
Design Principles for SuCESsFul Biosensors: Specific Fluorophore/Analyte Binding and Minimization of Fluorophore/Scaffold Interactions. 428:4228-4241. 2016
Directional phosphorylation and nuclear transport of the splicing factor SRSF1 is regulated by an RNA recognition motif. 428:2430-2445. 2016
High-resolution mapping of the folding transition state of a WW domain. 428:1617-1636. 2016
Monitoring ligand-induced protein ordering in drug discovery. 428:1290-1303. 2016
S-Nitrosylation induces structural and dynamical changes in a rhodanese family protein. 428:3737-3751. 2016
The kinetic stability of a full-length antibody light chain dimer determines whether endoproteolysis can release amyloidogenic variable domains. 428:4280-4297. 2016
Assembly states of FliM and FliG within the flagellar switch complex. 427:867-886. 2015
Conformational transitions that enable histidine kinase autophosphorylation and receptor array integration. 427:3890-3907. 2015
Architecture of the complex formed by large and small terminase subunits from bacteriophage P22. 427:3285-3299. 2015
ClickSeq: Fragmentation-free next-generation sequencing via click ligation of adaptors to stochastically terminated 3 '-azido cDNAs. 427:2610-2616. 2015
Structure of hepatitis C virus envelope glycoprotein E1 antigenic site 314-324 in complex with antibody IGH526. 427:2617-2628. 2015
The Pex1/Pex6 complex is a heterohexameric AAA+ motor with alternating and highly coordinated subunits. 427:1375-1388. 2015
DNA recognition by a σ(54) transcriptional activator from Aquifex aeolicus. 426:3553-3568. 2014
In silico derived small molecules bind the filovirus VP35 protein and inhibit its polymerase cofactor activity. 426:2045-2058. 2014
The histone H4 tail regulates the conformation of the ATP-binding pocket in the SNF2h chromatin remodeling enzyme. 426:2034-2044. 2014
NMR structures of α-proteobacterial ATPase-regulating ζ-subunits. 426:2547-2553. 2014
Structures of a bifunctional cell wall hydrolase CwlT containing a novel bacterial lysozyme and an NlpC/P60 DL-endopeptidase. 426:169-184. 2014
The N-terminal sequence of tyrosine hydroxylase is a conformationally versatile motif that binds 14-3-3 proteins and membranes. 426:150-168. 2014
The cleaved N-terminus of pVI binds peripentonal hexons in mature adenovirus. 426:1971-1979. 2014
The high-risk HPV16 E7 oncoprotein mediates interaction between the transcriptional coactivator CBP and the retinoblastoma protein pRb. 426:4030-4048. 2014
Architecture of the Soluble Receptor Aer2 Indicates an In-Line Mechanism for PAS and HAMP Domain Signaling. 425:886-901. 2013
Cryo-EM structures of the actin:tropomyosin filament reveal the mechanism for the transition from C- to M-state. 425:4544-4555. 2013
Dispersed sites of HIV Vif-dependent polyubiquitination in the DNA deaminase APOBEC3F. 425:1172-1182. 2013
Dissecting the molecular mechanism of IVIg therapy: the interaction between serum IgG and DC-SIGN is independent of antibody glycoform or Fc domain. 425:1253-1258. 2013
Hidden allostery in human glutathione transferase p1-1 unveiled by unnatural amino acid substitutions and inhibition studies. 425:1509-1514. 2013
Structural mechanism of GAF-regulated sigma(54) activators from Aquifex aeolicus. 425:156-170. 2013
β-hairpin-mediated nucleation of polyglutamine amyloid formation. 425:1183-1197. 2013
A protein.protein interaction platform involved in recruitment of GLD-3 to the FBF.Fem-3 mRNA complex. 425:738-754. 2013
Biochemical characterization of the Caenorhabditis elegans FBF. CPB-1 translational regulation complex identifies conserved protein interaction hotspots. 425:725-737. 2013
Characterization of the ribosome biogenesis landscape in E. coli using quantitative mass spectrometry. 425:767-779. 2013
Localized structural fluctuations promote amyloidogenic conformations in transthyretin. 425:977-988. 2013
Long-range effects and functional consequences of stabilizing mutations in the ankyrin repeat domain of IκBα. 425:902-913. 2013
Malachite green mediates homodimerization of antibody VL domains to form a fluorescent ternary complex with singular symmetric interfaces. 425:4595-4613. 2013
The disordered C-terminal domain of human DNA glycosylase NEIL1 contributes to its stability via intramolecular interactions. 425:2359-2371. 2013
Selective deactivation of serum IgG: a general strategy for the enhancement of monoclonal antibody receptor interactions. 420:1-7. 2012
Structure-guided directed evolution of highly selective p450-based magnetic resonance imaging sensors for dopamine and serotonin. 422:245-262. 2012
The evolution of cefotaximase activity in the TEM β-lactamase. 415:205-220. 2012
A molecular history of the amyloidoses. 421:142-159. 2012
Computational design of high-affinity epitope scaffolds by backbone grafting of a linear epitope. 415:175-192. 2012
DDX1 is an RNA-dependent ATPase involved in HIV-1 Rev function and virus replication. 415:61-74. 2012
Gating movement of acetylcholine receptor caught by plunge-freezing. 422:617-634. 2012
Immature and mature human astrovirus: structure, conformational changes, and similarities to hepatitis E virus. 422:650-658. 2012
Prion protein mPrP[F175A](121-231): structure and stability in solution. 423:496-502. 2012
Structural analysis of the quaking homodimerization interface. 423:766-781. 2012
Structure of an essential type iv pilus biogenesis protein provides insights into pilus and type ii secretion systems. 419:110-124. 2012
The metavinculin tail domain directs constitutive interactions with raver1 and vinculin RNA. 422:697-704. 2012
The structure of Aquifex aeolicus ribosomal protein S8 reveals a unique subdomain that contributes to an extremely tight association with 16S rRNA. 415:489-502. 2012
The structure of the NXF2/NXT1 heterodimeric complex reveals the combined specificity and versatility of the NTF2-like fold. 415:649-665. 2012
The transthyretin amyloidoses: from delineating the molecular mechanism of aggregation linked to pathology to a regulatory-agency-approved drug. 421:185-203. 2012
Engineering GST M2-2 for high activity with indene 1,2-oxide and indication of an H-site residue sustaining catalytic promiscuity. 412:111-120. 2011
Hotspot-centric de novo design of protein binders. 413:1047-1062. 2011
Mechanism of binding site conformational switching in the CD44-hyaluronan protein-carbohydrate binding interaction. 406:631-647. 2011
Structural biology by mass spectrometry: mapping protein interaction surfaces of membrane receptor complexes with ICAT. 409:481-482. 2011
Structure of an enclosed dimer formed by the Drosophila period protein. 413:561-572. 2011
The evolution of catalytic function in the HIV-1 protease. 408:792-805. 2011
Accessory mutations maintain stability in drug-resistant HIV-1 protease. 410:756-760. 2011
An RNA conformational switch regulates pre-18S rRNA cleavage. 405:3-17. 2011
Computational protein design using flexible backbone remodeling and resurfacing: case studies in structure-based antigen design. 405:284-297. 2011
Consequences of stabilizing the natively disordered f helix for the folding pathway of apomyoglobin. 411:248-263. 2011
Design and characterization of epitope-scaffold immunogens that present the motavizumab epitope from respiratory syncytial virus. 409:853-866. 2011
Design of in vitro symmetric complexes and analysis by hybrid methods reveal mechanisms of HIV capsid assembly. 410:534-552. 2011
Dynamic conformational equilibria in the physiological function of the Bombyx mori pheromone-binding protein. 408:922-931. 2011
Dynamic interaction of hsp90 with its client protein p53. 411:158-173. 2011
Light-induced conformational changes in full-length Arabidopsis thaliana cryptochrome. 413:128-137. 2011
Molecular architecture and connectivity of the budding yeast Mtw1 kinetochore complex. 405:548-559. 2011
Single-molecule studies reveal that dead box protein DDX1 promotes oligomerization of HIV-1 Rev on the Rev response element. 410:959-971. 2011
Site-specific coupling and sterically controlled formation of multimeric antibody fab fragments with unnatural amino acids. 406:595-603. 2011
Structure-based design of a protein immunogen that displays an hiv-1 gp41 neutralizing epitope. 414:460-476. 2011
Systematic chromosomal deletion of bacterial ribosomal protein genes. 413:751-761. 2011
The prohead-i structure of bacteriophage hk97: Implications for scaffold-mediated control of particle assembly and maturation. 408:541-554. 2011
The rela nuclear localization signal folds upon binding to i kappa b alpha. 405:754-764. 2011
The structure of the crispr-associated protein csa3 provides insight into the regulation of the crispr/cas system. 405:939-955. 2011
A novel quasi-species of glutathione transferase with high activity towards naturally occurring isothiocyanates evolves from promiscuous low-activity variants. 401:451-464. 2010
Multiple sequence signals direct recognition and degradation of protein substrates by the AAA plus protease HslUV. 403:420-429. 2010
Structural basis for featuring of steroid isomerase activity in alpha class glutathione transferases. 397:332-340. 2010
Topological frustration in beta alpha-repeat proteins: sequence diversity modulates the conserved folding mechanisms of alpha/beta/alpha sandwich proteins. 398:332-350. 2010
X-ray structures of the LXRα LBD in its homodimeric form and implications for heterodimer signaling. 399:120-132. 2010
A dynamic model of HIV integrase inhibition and drug resistance. 397:600-615. 2010
A single-domain llama antibody potently inhibits the enzymatic activity of botulinum neurotoxin by binding to the non-catalytic alpha-exosite binding region. 397:1106-1118. 2010
An enhanced system for unnatural amino acid mutagenesis in E. coli. 395:361-374. 2010
Backbone model of an aquareovirus virion by cryo-electron microscopy and bioinformatics. 397:852-863. 2010
Bacterial pleckstrin homology domains: A prokaryotic origin for the PH domain. 396:31-46. 2010
Building and refining protein models within cryo-electron microscopy density maps based on homology modeling and multiscale structure refinement. 397:835-851. 2010
Crystal structure of CYP24A1, a mitochondrial cytochrome P450 involved in vitamin D metabolism. 396:441-451. 2010
Crystal structure of fatty acid amide hydrolase bound to the carbamate inhibitor urb597: Discovery of a deacylating water molecule and insight into enzyme inactivation. 400:743-754. 2010
Crystal structure of the botulinum neurotoxin type G binding domain: insight into cell surface binding. 397:1287-1297. 2010
Crystal structure of the first eubacterial Mre11 nuclease reveals novel features that may discriminate substrates during DNA repair. 397:647-663. 2010
Directed evolution of an enhanced and highly efficient foki cleavage domain for zinc finger nucleases. 400:96-107. 2010
Disulfide bond stabilization of the hexameric capsomer of human immunodeficiency virus. 401:985-995. 2010
Energetic frustration of apomyoglobin folding: Role of the b helix. 396:1319-1328. 2010
Generation and characterization of a chimeric rabbit/human Fab for co-crystallization of HIV-1 Rev. 397:697-708. 2010
Hk97 maturation studied by crystallography and h/(2)h exchange reveals the structural basis for exothermic particle transitions. 397:560-574. 2010
Horse prion protein NMR structure and comparisons with related variants of the mouse prion protein. 400:121-128. 2010
Insights into substrate specificity of geranylgeranyl reductases revealed by the structure of digeranylgeranylglycerophospholipid reductase, an essential enzyme in the biosynthesis of archaeal membrane lipids. 404:403-417. 2010
NMR Structure of the SARS-CoV Nonstructural Protein 7 in Solution at pH 6.5. 402:619-628. 2010
Nmr solution structure and DNA-binding model of the DNA-binding domain of competence protein a. 398:248-263. 2010
Quantitative proteomic analysis of ribosome assembly and turnover in vivo. 403:331-345. 2010
SARS coronavirus unique domain: three-domain molecular architecture in solution and RNA binding. 400:724-742. 2010
Surrobodies with functional tails. 397:352-360. 2010
The effect of ribosome assembly cofactors on in vitro 30S subunit reconstitution. 398:1-7. 2010
Tm0486 from the hyperthermophilic anaerobe thermotoga maritima is a thiamin-binding protein involved in response of the cell to oxidative conditions. 400:463-476. 2010
Alternative exon 9-encoded relay domains affect more than one communication pathway in the Drosophila myosin head. 389:707-721. 2009
Carbohydrate and domain architecture of an immature antibody glycoform exhibiting enhanced effector functions. 387:1061-1066. 2009
Crystal structures of protein phosphatase-1 bound to nodularin-R and tautomycin: a novel scaffold for structure-based drug design of serine/threonine phosphatase inhibitors. 385:11-21. 2009
Effect of Mg(2+) and Na(+) on the nucleic acid chaperone activity of HIV-1 nucleocapsid protein: implications for reverse transcription. 386:773-788. 2009
HIV-1 nucleocapsid protein switches the pathway of transactivation response element RNA/DNA annealing from loop-loop "kissing" to "zipper". 386:789-801. 2009
Illuminating solution responses of a LOV domain protein with photocoupled small-angle X-ray scattering. 393:909-919. 2009
Insights from Xanthine and Uracil DNA Glycosylase Activities of Bacterial and Human SMUG1: Switching SMUG1 to UDG. 385:761-778. 2009
The design and characterization of oligospecific antibodies for simultaneous targeting of multiple disease mediators.. 393:672-692. 2009
A structural basis for the regulatory inactivation of DnaA. 385:368-380. 2009
Crystal structure of histidine phosphotransfer protein ShpA, an essential regulator of stalk biogenesis in Caulobacter crescentus. 390:686-698. 2009
Dynamics and stability in maturation of a T = 4 virus. 392:803-812. 2009
Efficient recovery of high-affinity antibodies from a single-chain fab yeast display library. 389:365-375. 2009
Interaction of the i kappa b alpha c-terminal pest sequence with nf-kappa b: Insights into the inhibition of nf-kappa b DNA binding by i kappa b alpha. 388:824-838. 2009
Prion protein NMR structure from tammar wallaby (Macropus eugenii) shows that the beta2-alpha2 loop is modulated by long-range sequence effects. 389:833-845. 2009
Structural and functional analysis of the globular head domain of p115 provides insight into membrane tethering. 391:26-41. 2009
Structural and motional contributions of the Bacillus subtilis ClpC N-domain to adaptor protein interactions. 387:639-652. 2009
Structural evaluation of potent NKT cell agonists: Implications for design of novel stimulatory ligands. 394:71-82. 2009
Superoxide dismutase from the eukaryotic thermophile alvinella pompejana: Structures, stability, mechanism, and insights into amyotrophic lateral sclerosis. 385:1534-1555. 2009
The determinants of stability and folding in evolutionarily diverged cytochromes c. 388:159-167. 2009
p38alpha MAP kinase C-terminal domain binding pocket characterized by crystallographic and computational analyses. 391:1-11. 2009
Alternative relay domains of Drosophila melanogaster myosin differentially affect ATPase activity, in vitro motility, myofibril structure and muscle function. 379:443-456. 2008
Emergence of novel enzyme quasi-species depends on the substrate matrix. 382:136-153. 2008
Modulating catalytic activity by unnatural amino acid residues in a GSH-binding loop of GST P1-1. 376:811-826. 2008
Spatially directed assembly of a heterotetrameric Cre-Lox synapse restricts recombination specificity. 378:653-665. 2008
Structural determinants of glutathione transferases with azathioprine activity identified by DNA shuffling of alpha class members. 375:1365-1379. 2008
Structure and regulatory mechanism of Aquifex aeolicus NtrC4: variability and evolution in bacterial transcriptional regulation. 384:1058-1075. 2008
Subdomain competition, cooperativity, and topological frustration in the folding of CheY. 382:485-495. 2008
Assembly architecture and DNA binding of the bacteriophage P22 terminase small subunit. 383:494-501. 2008
Autoinhibition of human dicer by its internal helicase domain. 380:237-243. 2008
Complex of a protective antibody with its ebola virus gp peptide epitope: Unusual features of a v lambda(x) light chain. 375:202-216. 2008
Crystal structure of Lsm3 octamer from Saccharomyces cerevisiae: Implications for Lsm ring organisation and recruitment. 377:1357-1371. 2008
Crystal structures of mouse CD1d-iGb3 complex and its cognate v alpha 14 T cell receptor suggest a model for dual recognition of foreign and self glycolipids. 377:1104-1116. 2008
Evolution of class-specific peptides targeting a hot spot of the Galphas subunit. 377:1406-1418. 2008
Generation, affinity maturation, and characterization of a human anti-human NKG2D monoclonal antibody with dual antagonistic and agonistic activity. 384:1143-1156. 2008
NMR structure of the Escherichia coli type 1 pilus subunit FimF and its interactions with other pilus subunits. 375:752-763. 2008
NMR structure of the bank vole prion protein at 20 degrees c contains a structured loop of residues 165-171. 383:306-312. 2008
Recent avian h5n1 viruses exhibit increased propensity for acquiring human receptor specificity. 381:1382-1394. 2008
Similarities and differences between frozen-hydrated, rigor acto-S1 complexes of insect flight and chicken skeletal muscles. 381:519-528. 2008
Stabilization of the human β2-adrenergic receptor TM4-TM3-TM5 helix interface by mutagenesis of Glu122(3.41), a critical residue in GPCR structure. 376:1305-1319. 2008
Structural and biochemical characterization of the therapeutic anabaena variabilis phenylalanine ammonia lyase. 380:623-635. 2008
Structural basis of guanine nucleotide exchange mediated by the t-cell essential vav1. 380:828-843. 2008
Structural insight into pH-induced conformational changes within the native human transthyretin tetramer. 382:1157-1167. 2008
Structure of antibody f425-b4e8 in complex with a v3 peptide reveals a new binding mode for hiv-1 neutralization. 375:969-978. 2008
The crystal structure of CD8 in complex with YTS156.7.7 Fab and interaction with other CD8 antibodies define the binding mode of CD8 alphabeta to MHC class I. 384:1190-1202. 2008
The kinetic and equilibrium molten globule intermediates of apoleghemoglobin differ in structure. 378:715-725. 2008
Transcriptional stability of cultured cells upon prion infection. 375:1222-1233. 2008
Transfer of flexibility between ankyrin repeats in i kappa b alpha upon formation of the nf-kappa b complex. 380:917-931. 2008
Visualisation of a kinesin-13 motor on microtubule end mimics. 377:647-654. 2008
Alternative S2 hinge regions of the myosin rod differentially affect muscle function, myofibril dimensions and myosin tail length. 367:1312-1329. 2007
Dynamic structure of retinylidene ligand of rhodopsin probed by molecular simulations. 372:906-917. 2007
High-resolution electron microscopy of helical specimens: A fresh look at Tobacco Mosaic Virus. 371:812-835. 2007
Hydrophobic cooperativity as a mechanism for amyloid nucleation. 368:894-901. 2007
Inhibition of mammalian glycan biosynthesis produces non-self antigens for a broadly neutralising, HIV-1 specific antibody. 372:16-22. 2007
Structural basis of DNA recognition by the alternative sigma-factor, sigma54. 369:1070-1078. 2007
The structure of isolated Synechococcus strain WH8102 carboxysomes as revealed by electron cryotomography. 372:764-773. 2007
An improved system for the generation and analysis of mutant proteins containing unnatural amino acids in Saccharomyces cerevisiae. 371:112-122. 2007
Cold-adaptation in sea-water-borne signal proteins: sequence and NMR structure of the pheromone En-6 from the Antarctic ciliate Euplotes nobilii. 372:277-286. 2007
Comparison of the catalytic parameters and reaction specificities of a phage and an archaeal flap endonuclease. 371:34-48. 2007
Crystal structures of a quorum-quenching antibody. 368:1392-1402. 2007
Domain interdependence in the biosynthetic assembly of CFTR. 365:981-994. 2007
Embryonic neural inducing factor churchill is not a DNA-binding zinc finger protein: Solution structure reveals a solvent-exposed beta-sheet and zinc binuclear cluster. 371:1274-1289. 2007
Evolution of programmable zinc finger-recombinases with activity in human cells. 367:802-813. 2007
Galanthamine and non-competitive inhibitor binding to ACh-binding protein: evidence for a binding site on non-alpha-subunit interfaces of heteromeric neuronal nicotinic receptors. 369:895-901. 2007
Identification and characterization of single chain anti-cocaine catalytic antibodies. 365:722-731. 2007
Maturation of shark single-domain (ignar) antibodies: Evidence for induced-fit binding. 367:358-372. 2007
NMR structure and functional characterization of a human cancer-related nucleoside triphosphatase. 367:788-801. 2007
Single-particle image reconstruction of a tetramer of hiv integrase bound to DNA. 366:286-294. 2007
Specific recognition of a DNA immunogen by its elicited antibody. 370:183-195. 2007
Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10. 365:1533-1544. 2007
Structural basis of ligand binding and release in insect pheromone-binding proteins: NMR structure of Antheraea polyphemus PBP1 at pH 4.5. 373:811-819. 2007
Structural characterization of zinc-deficient human superoxide dismutase and implications for ALS. 373:877-890. 2007
Structure of a high-affinity "mimotope" peptide bound to HIV-1-neutralizing antibody b12 explains its inability to elicit gp120 cross-reactive antibodies. 369:696-709. 2007
Structure of the wilms tumor suppressor protein zinc finger domain bound to DNA. 372:1227-1245. 2007
Binding-induced stabilization and assembly of the phage P22 tail accessory factor gp4. 363:558-576. 2006
Environmentally controlled invasion of cancer cells by engineered bacteria. 355:619-627. 2006
Identification of the key LMO2-binding determinants on Ldb1. 359:66-75. 2006
Mechanistic studies of mini-TAR RNA/DNA annealing in the absence and presence of HIV-1 nucleocapsid protein. 363:244-261. 2006
Structural basis of the suppressed catalytic activity of wild-type human glutathione transferase T1-1 compared to its W234R mutant. 355:96-105. 2006
The three-dimensional arcitecture of the EJC core. 360:743-749. 2006
A novel processive mechanism for DNA synthesis revealed by structure, modeling and mutagenesis of the accessory subunit of human mitochondrial DNA polymerase. 358:1229-1243. 2006
A structural perspective of the sequence variability within botulinum neurotoxin subtypes a1-a4. 362:733-742. 2006
Amyloid formation by recombinant full-length prion proteins in phospholipid bicelle solutions. 357:833-841. 2006
Antibody elbow angles are influenced by their light chain class. 357:1566-1574. 2006
Crystal structure of the TCR co-receptor CD8 alpha alpha in complex with monoclonal antibody YTS 105.18 Fab fragment at 2.88 A resolution. 358:347-354. 2006
Directed evolution of an anti-prion protein scfv fragment to an affinity of 1 pm and its structural interpretation. 363:75-97. 2006
GTP-dependent formation of a ribonucleoprotein subcomplex required for ribosome biogenesis. 356:432-443. 2006
Glycan microarray analysis of the hemagglutinins from modern and pandemic influenza viruses reveals different receptor specificities. 355:1143-1155. 2006
Identification of native and non-native structure in kinetic folding intermediates of apomyoglobin. 355:139-156. 2006
In meso structure of the cobalamin transporter, btub, at 1.95 Å resolution. 364:716-734. 2006
Induced fit and "lock and key" recognition of 5s RNA by zinc fingers of transcription factor IIIA. 357:275-291. 2006
Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1. 363:201-214. 2006
Pas domain allostery and light-induced conformational changes in photoactive yellow protein upon I-2 intermediate formation, probed with enhanced hydrogen/deuterium exchange mass spectrometry. 363:148-160. 2006
Retention of misfolded mutant transthyretin by the chaperone BiP/GRP78 mitigates amyloidogenesis. 356:469-482. 2006
Room to move: Crystallizing membrane proteins in swollen lipidic mesophases. 357:1605-1618. 2006
Solution structure of the Hdm2 C2H2C4 RING, a domain critical for ubiquitination of p53. 363:433-450. 2006
Structural basis for cooperative transcription factor binding to the cbp coactivator. 355:1005-1013. 2006
Structural determinants of rotavirus subgroup specificity mapped by cryo-electron microscopy. 356:209-221. 2006
Structural insights into the mechanisms of drug resistance in HIV-1 protease NL4-3. 356:967-981. 2006
Structure of aart, a designed six-finger zinc finger peptide, bound to DNA. 363:405-421. 2006
Structure of the Escherichia coli quorum sensing protein SdiA: Activation of the folding switch by acyl homoserine lactones. 355:262-273. 2006
Substrate recognition, protein dynamics, and iron-sulfur cluster in Pseudomonas aeruginosa adenosine 5'-phosphosulfate reductase. 364:152-169. 2006
High affinity targets of protein kinase inhibitors have similar residues at the positions energetically important for binding. 352:1134-1156. 2005
Structure of a loose dimer: an intermediate in nitric oxide synthase assembly. 352:932-940. 2005
Ultra-potent antibodies against respiratory syncytial virus: effects of binding kinetics and binding valence on viral neutralization. 350:126-144. 2005
Assembly of acanthamoeba myosin-ii minifilaments. Model of anti-parallel dimers based on em and x-ray diffraction of 2d and 3d crystals. 345:363-373. 2005
Composition and structure of the 80S ribosome from the green alga Chlamydomonas reinhardtii: 80S ribosomes are conserved in plants and animals. 351:266-279. 2005
Conformational diversity in nad(h) and interacting transhydrogenase nicotinamide nucleotide binding domains. 346:617-629. 2005
Cooperative reorganization of a 420 subunit virus capsid. 352:723-735. 2005
Cryoem structure at 9 Å resolution of an adenovirus vector targeted to hematopoietic cells. 349:526-537. 2005
Crystal structure of viral macrophage inflammatory protein i encoded by kaposi's sarcoma-associated herpesvirus at 1.7 a. 352:1019-1028. 2005
Directed evolution and identification of control regions of ColE1 plasmid replication origins using only nucleotide deletions. 351:763-775. 2005
Kinetic stabilization of the native state by protein engineering: Implications for inhibition of transthyretin amyloidogenesis. 347:841-854. 2005
Molecular basis for the specificity of p27 toward cyclin-dependent kinases that regulate cell division. 349:764-773. 2005
Nucleosomes in solution exist as a mixture of twist-defect states. 345:103-114. 2005
RNA helical packing in solution: NMR structure of a 30 kDa GAAA tetraloop-receptor complex. 351:371-382. 2005
Refined structure of the nicotinic acetylcholine receptor at 4 Å resolution. 346:967-989. 2005
Role of an active site adenine in hairpin ribozyme catalysis. 349:989-1010. 2005
Sequence determinants of a protein folding pathway. 351:383-392. 2005
Shape-specific nucleotide binding of single-stranded RNA by the GLD-1 STAR domain. 346:91-104. 2005
Solution structure and dynamics of LuxU from Vibrio harveyi, a phosphotransferase protein involved in bacterial quorum sensing. 347:297-307. 2005
Solution structure of the n-terminal zinc fingers of the xenopus laevis double-stranded rna-binding protein zfa. 351:718-730. 2005
Structures of the agouti signaling protein. 346:1059-1070. 2005
The binding interface between Bacillus stearothermophilus ribosomal protein S15 and its 5 '-translational operator mRNA. 351:280-290. 2005
The structure of the neurotoxin-associated protein HA33/A from Clostridium botulinum suggests a reoccurring beta-trefoil fold in the progenitor toxin complex. 346:1083-1093. 2005
Crystal structure of the spindle assembly checkpoint protein Bub3. 344:885-892. 2004
Helical shifts generate two distinct conformers in the atomic resolution structure of the CheA phosphotransferase domain from Thermotoga maritima. 341:1283-1294. 2004
Analysis of the class i aldolase binding site architecture based on the crystal structure of 2-deoxyribose-5-phosphate aldolase at 0.99 Å resolution. 343:1019-1034. 2004
Conformational states of cytochrome p450cam revealed by trapping of synthetic molecular wires. 344:455-469. 2004
Conversion of a mechanosensitive channel protein from a membrane-embedded to a water-soluble form by covalent modification with amphiphiles. 343:747-758. 2004
Crystal structure of human triggering receptor expressed on myeloid cells 1 (TREM-1) at 1.47 A. 342:1237-1248. 2004
Crystal structure of mouse triggering receptor expressed on myeloid cells 1 (trem-1) at 1.76 Å. 344:1175-1181. 2004
Crystal structure of the Drosophila peptidoglycan recognition protein (PGRP)-SA at 1.56 A resolution. 340:909-917. 2004
Differential arrangements of conserved building blocks among homologs of the rad50/mre11 DNA repair protein complex. 339:937-949. 2004
Evidence that a local refolding event triggers maturation of hk97 bacteriophage capsid. 340:419-433. 2004
Evolution of aldolase antibodies in vitro: Correlation of catalytic activity and reaction-based selection. 335:1007-1018. 2004
Improved breadth and potency of an hiv-1-neutralizing human single-chain antibody by random mutagenesis and sequential antigen panning. 335:209-219. 2004
In vivo selection of combinatorial libraries and designed affinity maturation of polydactyl zinc finger transcription factors for icam-1 provides new insights into gene regulation. 341:635-649. 2004
Ligand-induced conformational changes in the bacillus subtilis chemoreceptor mcpb determined by disulfide crosslinking in vivo. 344:919-928. 2004
NMR structure of the integral membrane protein OmpX. 336:1211-1221. 2004
Promoter-targeted phage display selections with preassembled synthetic zinc finger libraries for endogenous gene regulation. 340:599-613. 2004
Protein biophysical properties that correlate with crystallization success in thermotoga maritima: Maximum clustering strategy for structural genomics. 344:977-991. 2004
RNA tertiary structure and cooperative assembly of a large ribonucleoprotein complex. 344:395-407. 2004
Role of an active site guanine in hairpin ribozyme catalysis probed by exogenous nucleobase rescue. 340:233-251. 2004
Solution structure of the kix domain of cbp bound to the transactivation domain of c-myb. 337:521-534. 2004
Structural characterization of unfolded states of apomyoglobin using residual dipolar couplings. 340:1131-1142. 2004
Structure/function studies on a S-adenosyl-(L)-methionine-dependent uroporphyrinogen III C methyltransferase (SUMT), a key regulatory enzyme of tetrapyrrole biosynthesis. 344:419-433. 2004
The origin of enantioselectivity in aldolase antibodies: crystal structure, site-directed mutagenesis, and computational analysis. 343:1269-1280. 2004
The rad50 signature motif: Essential to atp binding and biological function. 335:937-951. 2004
The zinc-dependent redox switch domain of the chaperone hsp33 has a novel fold. 341:893-899. 2004
Thermodynamic dissection of the polymerizing and editing modes of a DNA polymerase. 336:673-693. 2004
Zz domain of cbp: An unusual zinc finger fold in a protein interaction module. 343:1081-1093. 2004
Cell transformation by the v-myc oncogene abrogates c-Myc/Max-mediated suppression of a C/EBP beta-dependent lipocalin gene. 333:33-46. 2003
Improved Gō-like models demonstrate the robustness of protein folding mechanisms towards non-native interactions. 334:309-325. 2003
Sequence, structure and energetic determinants of phosphopeptide selectivity of SH2 domains. 334:823-841. 2003
Structure-based active site profiles for genome analysis and functional family subclassification. 334:387-401. 2003
A humanized aldolase antibody for selective chemotherapy and adaptor immunotherapy. 332:889-899. 2003
ALS mutants of human superoxide dismutase form fibrous aggregates via framework destabilization. 332:601-615. 2003
Conformation of prpc on the cell surface as probed by antibodies. 326:475-483. 2003
Crystal structure of MHC class II I-Ab in complex with a human CLIP peptide: prediction of an I-Ab peptide-binding motif. 326:1157-1174. 2003
Crystal structures of nucleosome core particles in complex with minor groove DNA-binding ligands. 326:371-380. 2003
Folding of a beta-sheet protein monitored by real-time NMR spectroscopy. 328:1161-1171. 2003
Gelsolin domain 2 Ca2+ affinity determines susceptibility to furin proteolysis and familial amyloidosis of finnish type. 334:119-127. 2003
Hydration and packing are crucial to amyloidogenesis as revealed by pressure studies on transthyretin variants that either protect or worsen amyloid disease. 328:963-974. 2003
Inherent protein structural flexibility at the RNA-binding interface of L30e. 326:999-1004. 2003
Monomeric complex of human orphan estrogen related receptor-2 with DNA: A pseudo-dimer interface mediates extended half-site recognition. 327:819-832. 2003
NMR structure of the human doppel protein. 326:1549-1557. 2003
Nmr structure of a variant human prion protein with two disulfide bridges. 326:225-234. 2003
Rabbit immune repertoires as sources for therapeutic monoclonal antibodies: the impact of kappa allotype-correlated variation in cysteine content on antibody libraries selected by phage display. 325:325-335. 2003
Role of the b helix in early folding events in apomyoglobin: Evidence from site-directed mutagenesis for native-like long range interactions. 334:293-307. 2003
Structural basis for antibody catalysis of a cationic cyclization reaction. 329:69-83. 2003
Structural basis for recognition and catalysis by the bifunctional dctp deaminase and dutpase from methanococcus jannaschii. 331:885-896. 2003
Structural plasticity and the evolution of antibody affinity and specificity. 330:651-656. 2003
Structure analysis of peptide deformylases from Streptococcus pneumoniae, Staphylococcus aureus, Thermotoga maritima and Pseudomonas aeruginosa: Snapshots of the oxygen sensitivity of peptide deformylase. 330:309-321. 2003
Structure and reactivity of an asymmetric complex between hslv and i-domain deleted hslu, a prokaryotic homolog of the eukaryotic proteasome. 330:185-195. 2003
The refined structure of a protein catenane: The hk97 bacteriophage capsid at 3.44 Å resolution. 334:885-899. 2003
Thermodynamics of a designed protein catenane. 327:537-548. 2003
An ensemble of theta class glutathione transferases with novel catalytic properties generated by stochastic recombination of fragments of two mammalian enzymes. 318:59-70. 2002
Artificial protein cavities as specific ligand-binding templates: characterization of an engineered heterocyclic cation-binding site that preserves the evolved specificity of the parent protein. 315:845-857. 2002
Hybridization of alpha class subunits generating a functional glutathione transferase A1-4 heterodimer. 316:395-406. 2002
On the role of electrostatic interactions in the design of protein-protein interfaces. 318:161-177. 2002
The effects of ionic strength on protein stability: the cold shock protein family. 319:541-554. 2002
A general method to quantify quasi-equivalence in icosahedral viruses. 324:723-737. 2002
Activation of the nicotinic acetylcholine receptor involves a switch in conformation of the a subunits. 319:1165-1176. 2002
Base flexibility in HIV-2 TAR RNA mapped by solution (15)N, (13)C NMR relaxation. 317:263-278. 2002
Blocking transcription through a nucleosome with synthetic DNA ligands. 321:249-263. 2002
Contrasting IgG structures reveal extreme asymmetry and flexibility. 319:9-18. 2002
Crystal structure of a non-canonical high affinity peptide complexed with MHC class I: a novel use of alternative anchors. 318:1307-1316. 2002
Crystal structure of a non-canonical low-affinity peptide complexed with MHC class I: a new approach for vaccine design. 318:1293-1305. 2002
Crystal structure of hsiuv complexed with a vinyl sulfone inhibitor: Corroboration of a proposed mechanism of allosteric activation of hsiv by hsiu. 318:779-785. 2002
Crystal structures of two rat mhc class ia (rt1-a) molecules that are associated differentially with peptide transporter alleles tap-a and tap-b. 324:975-990. 2002
High pressure NMR reveals that apomyoglobin is an equilibrium mixture from the native to the unfolded. 320:311-319. 2002
Insights into Lou Gehrig's disease from the structure and instability of the A4V mutant of human Cu,Zn superoxide dismutase. 324:247-256. 2002
Mapping long-range contacts in a highly unfolded protein. 322:655-662. 2002
Native state hydrogen exchange study of suppressor and pathogenic variants of transthyretin. 320:821-832. 2002
Nmr structures of 36 and 73-residue fragments of the calreticulin p-domain. 322:773-784. 2002
Protein NMR structure determination with automated noe assignment using the new software candid and the torsion angle dynamics algorithm dyana. 319:209-227. 2002
Structural basis for mobility in the 1.1 Å crystal structure of the ng domain of thermus aquaticus ffh. 320:783-799. 2002
Structural comparison of bacterial and human iron-dependent phenylalanine hydroxylases: Similar fold, different stability and reaction rates. 320:645-661. 2002
Structure and activity of a thermostable thymine-DNA glycosylase: Evidence for base twisting to remove mismatched normal DNA bases. 315:373-384. 2002
The apomyoglobin folding pathway revisited: Structural heterogeneity in the kinetic burst phase intermediate. 322:483-489. 2002
The crystal structures of phosphopantetheine adenylyltransferase with bound substrates reveal the enzyme's catalytic mechanism. 315:487-495. 2002
The structure of apo human glutamate dehydrogenase details subunit communication and allostery. 318:765-777. 2002
Structure, function, and dynamics of the dimerization and DNA-binding domain of oncogenic transcription factor v-Myc. 307:1395-1410. 2001
Analysis of rapid, large-scale protein quaternary structural changes: Time-resolved x-ray solution scattering of nudaurelia capensis omega virus (n omega v) maturation. 311:803-814. 2001
Binding of neural cell adhesion molecules (n-cams) to the cellular prion protein. 314:1209-1225. 2001
Central domain assembly: thermodynamics and kinetics of S6 and S18 binding to an S15-RNA complex. 313:35-48. 2001
Concerted kinetic folding of a multidomain ribozyme with a disrupted loop-receptor interaction. 305:11-21. 2001
Crystal structure and novel recognition motif of rho adp-ribosylating c3 exoenzyme from clostridium botulinum: Structural insights for recognition specificity and catalysis. 305:95-107. 2001
Crystal structure of a cocaine-binding antibody. 311:9-15. 2001
Crystal structure of an isolated V(alpha) domain of the 2C T-cell receptor. 314:1-8. 2001
Expanding the genetic code: selection of efficient suppressors of four-base codons and identification of "shifty" four-base codons with a library approach in Escherichia coli. 307:755-769. 2001
Hairpin ribozymes with four-way helical junctions mediate intracellular RNA ligation. 309:893-902. 2001
Interaction of the Bacillus stearothermophilus ribosomal protein S15 with its 5 '-translational operator mRNA. 314:413-422. 2001
Localization of membrane permeabilization and receptor binding sites on the vp4 hemagglutinin of rotavirus: Implications for cell entry. 314:985-992. 2001
Nmr structure of the euplotes raikovi pheromone er-23 and identification of its five disulfide bonds. 313:923-931. 2001
Recognition templates for predicting adenylate-binding sites in proteins. 314:1245-1255. 2001
Refined crystallographic structure of pseudomonas aeruginosa exotoxin a and its implications for the molecular mechanism of toxicity. 314:823-837. 2001
Sequence-specific recognition of DNA in the nucleosome by pyrrole-imidazole polyamides. 309:615-629. 2001
Solution structure of Escherichia coli glutaredoxin-2 shows similarity to mammalian glutathione-S-transferases. 310:907-918. 2001
Solution structure of the third immunoglobulin domain of the neural cell adhesion molecule N-CAM: can solution studies define the mechanism of homophilic binding?. 311:161-172. 2001
Structural basis for a disfavored elimination reaction in catalytic antibody 1D4. 314:93-102. 2001
Structural biochemistry of a type 2 rnase h: Rna primer recognition and removal during DNA replication. 307:541-556. 2001
Structure and mechanism of the ruvb holliday junction branch migration motor. 311:297-310. 2001
Structure-activity relationships in flexible protein domains: Regulation of Rho GTPases by RhoGDI and D4 GDI. 305:121-135. 2001
The folding mechanism of a beta-sheet: the WW domain. 311:373-393. 2001
Uba domains mediate protein-protein interactions between two DNA damage-inducible proteins. 313:955-963. 2001
Examination of the transcription factor NtcA-binding motif by in vitro selection of DNA sequences from a random library. 301:783-793. 2000
Structural effects of DNA sequence on T.A recognition by hydroxypyrrole/pyrrole pairs in the minor groove. 295:557-567. 2000
Structures of thermolabile mutants of human glutathione transferase P1-1. 302:295-302. 2000
Active and inhibited human catalase structures: Ligand and nadph binding and catalytic mechanism. 296:295-309. 2000
Alternative conformations of a nucleic acid four-way junction. 300:93-102. 2000
Aminoglycoside binding in the major groove of duplex rna: The thermodynamic and electrostatic forces that govern recognition. 298:95-110. 2000
Catalysis of decarboxylation by a preorganized heterogeneous microenvironment: Crystal structures of abzyme 21D8. 302:1213-1225. 2000
Conformational flexibility of b-DNA at 0.74 Å resolution: D(ccagtactgg)(2). 296:787-801. 2000
Cu,Zn superoxide dismutase structure from a microbial pathogen establishes a class with a conserved dimer interface. 296:145-153. 2000
DNA-induced alpha-helix capping in conserved linker sequences is a determinant of binding affinity in Cys(2)-His(2) zinc fingers. 295:719-727. 2000
Deuterium-proton exchange on the native wild-type transthyretin tetramer identifies the stable core of the individual subunits and indicates mobility at the subunit interface. 303:555-565. 2000
Electron microscopic evidence for the assembly of soluble pentameric extracellular domains of the nicotinic acetylcholine receptor. 303:185-196. 2000
Homodimeric peptides displayed by the major coat protein of filamentous phage. 300:307-320. 2000
Insights into the molecular recognition of the 5 '-gnn-3 ' family of DNA sequences by zinc finger domains. 303:489-502. 2000
Large conformational changes in the maturation of a simple rna virus, nudaurelia capensis omega virus (n omega v). 299:573-584. 2000
Ligand-induced stabilization of PPARgamma monitored by NMR spectroscopy: implications for nuclear receptor activation. 298:187-194. 2000
Mapping the transition state of the WW domain beta-sheet. 298:283-292. 2000
NMR and molecular dynamics studies of the hydration of a zinc finger-DNA complex. 302:1101-1117. 2000
NMR solution structure of the inserted domain of human leukocyte function associated antigen-1. 295:1251-1264. 2000
Nmr structure of the sterol carrier protein-2: Implications for the biological role. 295:595-603. 2000
Pulling chromatin fibers: Computer simulations of direct physical micromanipulations. 295:29-40. 2000
Solution structure and acetyl-lysine binding activity of the GCN5 bromodomain. 304:355-370. 2000
Solution structure of the TAZ2 (CH3) domain of the transcriptional adaptor protein CBP. 303:243-253. 2000
Solution structure of the cysteine-rich domain of the Escherichia coli chaperone protein DnaJ. 300:805-818. 2000
Structure and function of the hairpin ribozyme. 297:269-291. 2000
Structure of a mutant EF-G reveals domain III and possibly the fusidic acid binding site. 303:593-603. 2000
Structure of a thioredoxin-like 2fe-2s ferredoxin from aquifex aeolicus. 300:587-595. 2000
Structure of native and expanded sobemoviruses by electron cryo-microscopy and image reconstruction. 303:197-211. 2000
Structure of the CAD domain of caspase-activated DNase and interaction with the CAD domain of its inhibitor. 297:1121-1128. 2000
Structure of the PHD zinc finger from human Williams-Beuren syndrome transcription factor. 304:723-729. 2000
Structure-activity relationships in a peptidic alpha 7 nicotinic acetylcholine receptor antagonist. 304:911-926. 2000
The high resolution crystal structure of green abalone sperm lysin: Implications for species-specific binding of the egg receptor. 296:1225-1234. 2000
The kinetic mechanism of the hairpin ribozyme in vivo: Influence of RNA helix stability on intracellular cleavage kinetics. 295:693-707. 2000
The structural basis for in situ activation of DNA alkylation by duocarmycin sa. 300:1195-1204. 2000
Benzoic acid derivatives induce recovery of catalytic activity in the partially inactive Met208Lys mutant of human glutathione transferase A1-1. 288:787-800. 1999
Evolution of differential substrate specificities in Mu class glutathione transferases probed by DNA shuffling. 287:265-276. 1999
Mutational analysis and NMR spectroscopy of quail cysteine and glycine-rich protein CRP2 reveal an intrinsic segmental flexibility of LIM domains. 292:893-908. 1999
Three-dimensional placement of the conserved 530 loop of 16 S rRNA and of its neighboring components in the 30 S subunit. 286:521-540. 1999
Unfolding and refolding of human glyoxalase II and its single-tryptophan mutants. 291:481-490. 1999
Antibody binding defines a structure for an epitope that participates in the prpc -> prpsc conformational change. 293:855-863. 1999
Coevolution and subsite decomposition for the design of resistance-evading HIV-1 protease inhibitors. 287:77-92. 1999
Conformational changes of the bs2 operator DNA upon complex formation with the antennapedia homeodomain studied by NMR with c-13/n-15-labeled DNA. 292:609-617. 1999
Effect of H helix destabilizing mutations on the kinetic and equilibrium folding of apomyoglobin. 285:269-282. 1999
Human glutathione transferase a4-4 crystal structures and mutagenesis reveal the basis of high catalytic efficiency with toxic lipid peroxidation products. 288:427-439. 1999
Identification of a minimal domain of 5 S ribosomal RNA sufficient for high affinity interactions with the RNA-specific zinc fingers of transcription factor IIIA. 291:549-560. 1999
Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm. 293:321-331. 1999
Local folding coupled to RNA binding in the yeast ribosomal protein L30. 292:345-359. 1999
Minor groove DNA-protein contacts upstream of a tRNA gene detected with a synthetic DNA binding ligand. 286:973-981. 1999
Motor protein decoration of microtubules grown in high salt conditions reveals the presence of mixed lattices. 287:287-292. 1999
Mutational analysis of the affinity maturation of antibody 48G7. 294:1191-1201. 1999
Nicotinic acetylcholine receptor at 4.6 Å resolution: Transverse tunnels in the channel wall. 288:765-786. 1999
Nmr structure of the sea urchin (strongylocentrotus purpuratus) metallothionein mta. 291:417-428. 1999
Projection structure of a plant vacuole membrane aquaporin by electron cryo-crystallography. 294:1337-1349. 1999
Protein mimicry of DNA from crystal structures of the uracil-DNA glycosylase inhibitor protein and its complex with escherichia coli uracil-DNA glycosylase. 287:331-346. 1999
Roles for glycosylation of cell surface receptors involved in cellular immune recognition. 293:351-366. 1999
Sequence homology and structural analysis of the clostridial neurotoxins. 291:1091-1104. 1999
Structural analyses of CREB-CBP transcriptional activator-coactivator complexes by NMR spectroscopy: implications for mapping the boundaries of structural domains. 287:859-865. 1999
Structural basis for amide hydrolysis catalyzed by the 43C9 antibody. 291:329-345. 1999
The internal equilibrium of the hairpin ribozyme: Temperature, ion and pH effects. 286:1009-1024. 1999
Calculations on folding of segment B1 of streptococcal protein G. 278:439-456. 1998
Structure-activity relationships and thermal stability of human glutathione transferase P1-1 governed by the H-site residue 105. 278:687-698. 1998
A bisubstrate analog induces unexpected conformational changes in phosphoglycerate kinase from trypanosoma brucei. 279:1137-1148. 1998
Analysis of hapten binding and catalytic determinants in a family of catalytic antibodies. 275:95-111. 1998
DNA-induced conformational changes are the basis for cooperative dimerization by the DNA binding domain of the retinoid X receptor. 284:533-539. 1998
Fast folding mutants of the Tetrahymena group I ribozyme reveal a rugged folding energy landscape. 281:609-620. 1998
High-resolution solution structure of the retinoid X receptor DNA-binding domain. 281:271-284. 1998
Imaging RNA and dynamic protein segments with low-resolution virus crystallography: experimental design, data processing and implications of electron density maps. 284:1439-1452. 1998
Influence of cofactor binding and active site occupancy on the conformation of the macromolecular substrate exosite of factor viia. 277:959-971. 1998
Protein and Mg(2+)-induced conformational changes in the S15 binding site of 16 S ribosomal RNA. 275:453-464. 1998
Protein subunit interactions and structural integrity of amyloidogenic transthyretins: Evidence from electrospray mass spectrometry. 281:553-564. 1998
Recommendations for the presentation of NMR structures of proteins and nucleic acids. 280:933-952. 1998
Sedimentation and electrophoretic migration of DNA knots and catenanes. 278:1-3. 1998
Self-organizing neural networks bridge the biomolecular resolution gap. 284:1247-1254. 1998
Structural basis for the binding of an anti-cytochrome c antibody to its antigen: Crystal structures of FabE8 cytochrome c complex to 1.8 Å resolution and FabE8 to 2.26 Å resolution. 281:301-322. 1998
Structure of azotobacter vinelandii 7fe ferredoxin at 1.35 Å resolution and determination of the fe-s bonds with 0.01 Å accuracy. 278:629-639. 1998
The 1.25 A resolution refinement of the cholera toxin B-pentamer: evidence of peptide backbone strain at the receptor-binding site. 282:1043-1059. 1998
The mechanism of an inhibitory antibody on TF-initiated blood coagulation revealed by the crystal structures of human tissue factor, Fab 5G9 and TF.G9 complex. 275:873-894. 1998
Thermodynamics of a reverse turn motif. Solvent effects and side-chain packing. 270:305-317. 1997
A conformational transition at the n terminus of the prion protein features in formation of the scrapie isoform. 273:614-622. 1997
Conformational changes due to calcium-induced calmodulin dissociation in brush border myosin i-decorated f-actin revealed by cryoelectron microscopy and image analysis. 269:548-557. 1997
Crystal structures of the free and liganded form of an esterolytic catalytic antibody. 268:390-400. 1997
Fine tuning a molecular motor: The location of alternative domains in the drosophila myosin head. 271:1-6. 1997
Flexible linker in the RNA polymerase alpha subunit facilitates the independent motion of the C-terminal activator contact domain. 267:953-962. 1997
High resolution solution structure of a DNA duplex alkylated by the antitumor agent duocarmycin SA. 272:237-252. 1997
Importance of minor groove binding zinc fingers within the transcription factor IIIA-DNA complex. 274:439-445. 1997
Mapping the protein surface of human immunodeficiency virus type 1 gp120 using human monoclonal antibodies from phage display libraries. 267:684-695. 1997
Molecular recognition in signal transduction: The interaction surfaces of the spo0f response regulator with its cognate phosphorelay proteins revealed by alanine scanning mutagenesis. 272:200-212. 1997
Motor domains of kinesin and ncd interact with microtubule protofilaments with the same binding geometry. 265:553-564. 1997
Multiple cycles of global unfolding of groel-bound cyclophilin a evidenced by NMR. 271:803-818. 1997
Nmr solution structure of the pathogenesis-related protein p14a. 266:576-593. 1997
Nuclear protein import is decreased by engineered mutants of nuclear transport factor 2 (ntf2) that do not bind gdp-ran. 272:716-730. 1997
Opposite effect of counterions on the persistence length of nicked and non-nicked DNA. 266:711-721. 1997
Partially folded states of the capsid protein of cowpea severe mosaic virus in the disassembly pathway. 273:456-466. 1997
Projection structure of VP6, the rotavirus inner capsid protein, and comparison with bluetongue VP7. 272:362-368. 1997
Quasi-equivalent viruses: A paradigm for protein assemblies. 269:665-675. 1997
Solution structure of the HIV-2 TAR-argininamide complex. 267:624-639. 1997
Solution structure of the first three zinc fingers of TFIIIA bound to the cognate DNA sequence: Determinants of affinity and sequence specificity. 273:183-206. 1997
Species-specific tRNA recognition in relation to tRNA synthetase contact residues. 269:1-9. 1997
Structure-based design of a constrained peptide mimic of the HIV-1 V3 loop neutralization site. 266:31-39. 1997
The NMR solution conformation of unligated human cyclophilin A. 272:64-81. 1997
The NMR solution structure of the non-classical homeodomain from the rat liver lfb1/hnf1 transcription factor. 267:673-683. 1997
Three-dimensional structure of brush border myosin-i at similar to 20 Å resolution by electron microscopy and image analysis. 266:331-342. 1997
Torsion angle dynamics for NMR structure calculation with the new program dyana. 273:283-298. 1997
Transcriptional analysis of the caulobacter 4.5 s rna ffs gene and the physiological basis of an ffs mutant with a ts phenotype. 272:665-676. 1997
Two conformations of RNA polymerase II revealed by electron crystallography. 272:536-540. 1997
A mutation in the human cyclin-dependent kinase interacting protein, ckshs2, interferes with cyclin-dependent kinase binding and biological function, but preserves protein structure and assembly. 261:646-657. 1996
A novel promoter motif for caulobacter cell cycle-controlled DNA replication genes. 264:412-425. 1996
Crystal structures of apolipoprotein(a) kringle iv37 free and complexed with 6-aminohexanoic acid and with p-aminomethylbenzoic acid: Existence of novel and expected binding modes. 256:751-761. 1996
Interaction of the Bacillus stearothermophilus ribosomal protein S15 with 16 S rRNA: I. Defining the minimal RNA site. 261:536-549. 1996
Interaction of the Bacillus stearothermophilus ribosomal protein S15 with 16 S rRNA: II. Specificity determinants of RNA-protein recognition. 261:550-567. 1996
Is apomyoglobin a molten globule? Structural characterization by NMR. 263:531-538. 1996
Isolation, characterization and evolution of nine pufferfish (Fugu rubripes) actin genes. 259:655-665. 1996
MPD and DNA bending in crystals and in solution. 256:108-125. 1996
NMR solution structure of Cu(I) rusticyanin from Thiobacillus ferrooxidans: structural basis for the extreme acid stability and redox potential. 263:752-767. 1996
Nmr structure of the j-domain and the gly/phe-rich region of the escherichia coli dnaj chaperone. 260:236-250. 1996
Polarity of 2-d and 3-d maps of tubulin sheets and motor-decorated sheets. 263:114-119. 1996
Projection structure of the nicotinic acetylcholine receptor: Distinct conformations of the alpha subunits. 257:586-596. 1996
Protein and DNA requirements for the transcription factor IIIA-induced distortion of the 5 S rRNA gene promoter. 262:600-614. 1996
Specialization of the DNA-cleaving activity of a group I ribozyme through in vitro evolution. 262:31-42. 1996
Structural role of a buried salt bridge in the 434 repressor DNA-binding domain. 264:1002-1012. 1996
Surface display of proteins on bacteriophage lambda heads. 262:21-30. 1996
The 2.8 Å structure of a T=4 animal virus and its implications for membrane translocation of RNA. 261:1-10. 1996
The bacillus subtilis response regulator spooa stimulates transcription of the spoiig operon through modification of rna polymerase promoter complexes. 256:436-448. 1996
Three-dimensional structure of ncd-decorated microtubules obtained by a back-projection method. 260:743-755. 1996
Functional significance of arginine 15 in the active site of human class alpha glutathione transferase A1-1.. 247:765-773. 1995
Glutathione transferases with novel active sites isolated by phage display from a library of random mutants. 250:115-122. 1995
Prediction of quaternary structure of coiled coils. Application to mutants of the GCN4 leucine zipper. 251:448-467. 1995
Binding of the junction-resolving enzyme bacteriophage-T7 endonuclease-I to DNA - separation of binding and catalysis by mutation. 246:95-107. 1995
Cdr walking mutagenesis for the affinity maturation of a potent human anti-hiv-1 antibody into the picomolar range. 254:392-403. 1995
Crystal-structure of the human cell-cycle protein ckshs1 - single-domain fold with similarity to kinase n-lobe domain. 249:835-842. 1995
Crystal-structures of a schistosomal drug and vaccine target - glutathione-s-transferase from schistosoma-japonica and its complex with the leading antischistosomal drug praziquantel. 246:21-27. 1995
Determination of DNA persistence length by cryoelectron microscopy - separation of the static and dynamic contributions to the apparent persistence length of DNA. 254:579-591. 1995
Interaction of the RNA-binding fingers of Xenopus transcription factor IIIA with specific regions of 5-S ribosomal-RNA. 248:44-57. 1995
Internal mobility of the basic pancreatic trypsin-inhibitor in solution - a comparison of NMR spin relaxation measurements and molecular-dynamics simulations. 246:356-365. 1995
Repression of vertebrate RNA-polymerase-III transcription by DNA-binding proteins located upstream from the transcription start site. 250:315-326. 1995
The modular character of a DNA junction-resolving enzyme - a zinc-binding motif in bacteriophage-T4 endonuclease-VII. 252:596-610. 1995
Towards structure-based drug design - crystal-structure of a multisubstrate adduct complex of glycinamide ribonucleotide transformylase at 1.96 Å resolution. 249:153-175. 1995
Use of flow-cytometry to identify a caulobacter 4.5 s rna temperature-sensitive mutant defective in the cell-cycle. 251:346-365. 1995
Prediction of the folding pathways and structure of the GCN4 leucine zipper.. 237:361-367. 1994
Catalytic antibody model and mutagenesis implicate arginine in transition-state stabilization. 235:1098-1116. 1994
Crystal-structure of a peptide complex of antiinfluenza peptide antibody-Fab-26/9 - comparison of 2 different antibodies bound to the same peptide antigen. 241:534-556. 1994
Crystal-structures of aconitase with trans-aconitate and nitrocitrate bound. 237:437-451. 1994
Crystallization and preliminary crystallographic analysis of peptide-n-4-(n-acetyl-beta-d-glucosaminyl)asparagine amidase pngase-f. 241:622-623. 1994
Crystallization and preliminary crystallographic data for rab guanine-nucleotide dissociation inhibitor (rabgdi) from bovine brain. 244:469-473. 1994
Determination of the nuclear-magnetic-resonance structure of the DNA-binding domain of the p22 c2 repressor (1 to 76) in solution and comparison with the DNA-binding domain of the 434 repressor. 235:1003-1020. 1994
Diffraction quality crystals of protein-x from azotobacter-vinelandii. 241:620-621. 1994
Nuclear magnetic resonance (15)N and (1)H resonance assignments and global fold of rusticyanin. Insights into the ligation and acid stability of the blue copper site. 244:370-384. 1994
Nuclear-magnetic-resonance solution structure of the fushi-tarazu homeodomain from drosophila and comparison with the antennapedia homeodomain. 238:333-345. 1994
Relative contributions of the zinc fingers of transcription factor IIIA to the energetics of DNA-binding. 244:23-35. 1994
Simultaneous refinement of the structure of bpti against NMR data measured in solution and x-ray-diffraction data measured in single-crystals. 241:588-599. 1994
Solution structure of carbonmonoxy myoglobin determined from nuclear-magnetic-resonance distance and chemical-shift constraints. 244:183-197. 1994
Stabilization of a type VI turn in a family of linear peptides in water solution. 243:736-753. 1994
Structural-analysis of antibody specificity - detailed comparison of 5 fab'-steroid complexes. 241:663-690. 1994
Structure of four-way DNA junctions containing a nick in one strand. 238:62-74. 1994
Structure of phaseolin at 2.2 Å resolution - implications for a common vicilin/legumin structure and the genetic-engineering of seed storage proteins. 238:748-776. 1994
The crystal-structure of C-C-A-T-T-A-A-T-G-G - implications for bending of B-DNA at T-A steps. 239:79-96. 1994
The nuclear-magnetic-resonance solution structure of the mixed disulfide between escherichia-coli glutaredoxin(c14s) and glutathione. 235:1585-1597. 1994
The refined three-dimensional structure of an insect virus at 2.8-Å resolution. 235:565-586. 1994
Three-dimensional structure of a type VI turn in a linear peptide in water solution. Evidence for stacking of aromatic rings as a major stabilizing factor. 243:754-766. 1994
Structure determination and refinement of human alpha class glutathione transferase A1-1, and a comparison with the Mu and Pi class enzymes. 232:192-212. 1993
Detailed analysis of the free and bound conformations of an antibody - x-ray structures of fab 17/9 and 3 different fab-peptide complexes. 234:1098-1118. 1993
Determination of the nuclear-magnetic-resonance solution structure of an antennapedia homeodomain-DNA complex. 234:1084-1094. 1993
Hydration of proteins - a comparison of experimental residence times of water-molecules solvating the bovine pancreatic trypsin-inhibitor with theoretical-model calculations. 231:1040-1048. 1993
Model studies relating nuclear-magnetic-resonance data with the 3-dimensional structure of protein-DNA complexes. 234:1094-1097. 1993
Molecular profile of an antibody-response to hiv-1 as probed by combinatorial libraries. 230:812-823. 1993
Nicotinic acetylcholine-receptor at 9 Å resolution. 229:1101-1124. 1993
Nuclear-magnetic-resonance solution structure of dendrotoxin-k from the venom of dendroaspis-polylepis-polylepis. 234:735-750. 1993
Nuclear-magnetic-resonance solution structure of the pheromone er-10 from the ciliated protozoan euplotes-raikovi. 231:800-816. 1993
Nuclear-magnetic-resonance spectroscopy of a DNA complex with the uniformly c-13-labeled antennapedia homeodomain and structure determination of the DNA-bound homeodomain. 234:1070-1083. 1993
Purification, crystallization and space group determination of DNA-repair enzyme exonuclease-iii from escherichia-coli. 229:239-242. 1993
Three-dimensional structure of an anti-steroid Fab' and progesterone-Fab' complex. 231:103-118. 1993
Comparison of the solution conformations of human zn7 -metallothionein-2 and cd7 -metallothionein-2 using nuclear-magnetic-resonance spectroscopy. 225:433-443. 1992
Crystal-structure of glycinamide ribonucleotide transformylase from escherichia-coli at 3.0 Å resolution - a target enzyme for chemotherapy. 227:283-292. 1992
Crystallization and crystallographic characterization of the iron sulfur-containing DNA-repair enzyme endonuclease-iii from escherichia-coli. 227:347-351. 1992
Crystallization of murine major histocompatibility complex class-i h-2kb with single peptides. 228:975-982. 1992
Determination of a high-quality nuclear-magnetic-resonance solution structure of the bovine pancreatic trypsin-inhibitor and comparison with 3 crystal-structures. 227:757-775. 1992
Determination of the nuclear-magnetic-resonance solution structure of the DNA-binding domain (residues 1 to 69) of the 434 repressor and comparison with the x-ray crystal-structure. 223:743-767. 1992
Folding of peptide fragments comprising the complete sequence of proteins. Models for initiation of protein folding. I. Myohemerythrin. 226:795-817. 1992
Folding of peptide fragments comprising the complete sequence of proteins. Models for initiation of protein folding. II. Plastocyanin. 226:819-835. 1992
Impact of protein protein contacts on the conformation of thrombin-bound hirudin studied by comparison with the nuclear-magnetic-resonance solution structure of hirudin(1-51). 228:1206-1211. 1992
Membrane topology and quaternary structure of cardiac gap junction ion channels. 223:929-948. 1992
Nuclear-magnetic-resonance solution structure of hirudin(1-51) and comparison with corresponding 3-dimensional structures determined using the complete 65-residue hirudin polypeptide-chain. 228:1193-1205. 1992
Nuclear-magnetic-resonance solution structure of the alpha-neurotoxin from the black mamba (dendroaspis-polylepis-polylepis). 227:1118-1135. 1992
Specific interaction of the 1st-3 zinc fingers of TFIIIA with the internal control region of the Xenopus 5S RNA gene. 223:857-871. 1992
The interdependence of protein surface-topography and bound water-molecules revealed by surface accessibility and fractal density measures. 228:13-22. 1992
Biochemical implications from the variable gene-sequences of an anti-cytochrome-c antibody and crystallographic characterization of its antigen-binding fragment in free and antigen-complexed forms. 221:455-462. 1991
Characterization of the memory gene dunce of Drosophila melanogaster. 222:553-565. 1991
Crystallization and preliminary-x-ray analysis of botulinum neurotoxin type-a. 222:877-880. 1991
Effects of base mismatches on the structure of the four-way DNA junction. 221:147-161. 1991
Efficient computation of 3-dimensional protein structures in solution from nuclear-magnetic-resonance data using the program diana and the supporting programs caliba, habas and glomsa. 217:517-530. 1991
High-resolution solution structure of reduced french bean plastocyanin and comparison with the crystal-structure of poplar plastocyanin. 221:533-555. 1991
Refined crystal-structure of cd, zn metallothionein at 2.0 a resolution. 221:1269-1293. 1991
Sequence-specific h-1-NMR assignments and determination of the 3-dimensional structure of reduced escherichia-coli glutaredoxin. 221:1311-1324. 1991
Structure determination of the antp(c39- s) homeodomain from nuclear-magnetic-resonance data in solution using a novel strategy for the structure calculation with the programs diana, caliba, habas and glomsa. 217:531-540. 1991
Structure, function and properties of antibody binding sites. 217:133-151. 1991
Amide proton-exchange in human metallothionein-2 measured by nuclear-magnetic-resonance spectroscopy. 214:781-786. 1990
Crystallographic characterization of a Cu,Zn superoxide-dismutase from Photobacterium-leiognathi. 212:449-451. 1990
Determination of the 3-dimensional structure of the antennapedia homeodomain from drosophila in solution by h-1 nuclear-magnetic-resonance spectroscopy. 214:183-197. 1990
Establishment of denovo DNA methylation patterns - transcription factor binding and deoxycytidine methylation at cpg and non-cpg sequences in an integrated adenovirus promoter. 214:673-683. 1990
Structural homology among 4 nodaviruses as deduced by sequencing and x-ray crystallography. 214:423-435. 1990
Three-dimensional structure of human [113Cd7]metallothionein-2 in solution determined by nuclear magnetic resonance spectroscopy. 214:765-779. 1990
Trigonal crystals of porcine mitochondrial aspartate-aminotransferase. 215:341-344. 1990
Crystallization of GST2, a human class alpha glutathione transferase. 208:369-370. 1989
Comparison of the high-resolution structures of the alpha-amylase inhibitor tendamistat determined by nuclear magnetic-resonance in solution and by x-ray-diffraction in single-crystals. 206:677-687. 1989
Ermc leader peptide - amino-acid sequence critical for induction by translational attenuation. 206:69-79. 1989
On the assembly of sickle hemoglobin fascicles. 206:637-649. 1989
Refinement of the fe-7 ferredoxin from azotobacter-vinelandii at 1.9-a resolution. 205:545-555. 1989
Solution of the phase problem in the x-ray-diffraction method for proteins with the nuclear magnetic-resonance solution structure as initial model - patterson search and refinement for the alpha-amylase inhibitor tendamistat. 206:669-676. 1989
Complete assignment of the h-1 nuclear magnetic-resonance spectrum of french bean plastocyanin - application of an integrated approach to spin system-identification in proteins. 202:603-622. 1988
Complete assignment of the h-1 nuclear magnetic-resonance spectrum of french bean plastocyanin - sequential resonance assignments, secondary structure and global fold. 202:623-636. 1988
Conformation of cd7 -metallothionein-2 from rat-liver in aqueous-solution determined by nuclear magnetic-resonance spectroscopy. 203:251-268. 1988
Crystallization of a small fragment of an aminoacyl tRNA synthetase. 203:521-522. 1988
Determination of the complete 3-dimensional structure of the alpha-amylase inhibitor tendamistat in aqueous-solution by nuclear magnetic-resonance and distance geometry. 204:675-724. 1988
Evidence for a unique first position codon-anticodon mismatch in vivo. 201:451-454. 1988
Folding of immunogenic peptide fragments of proteins in water solution. I. Sequence requirements for the formation of a reverse turn. 201:161-200. 1988
Folding of immunogenic peptide fragments of proteins in water solution. II. The nascent helix. 201:201-217. 1988
Reactivation of the methylation-inactivated late e2a promoter of adenovirus type-2 by e1a (13-s) functions. 202:255-270. 1988
Statistical positioning of nucleosomes by specific protein-binding to an upstream activating sequence in yeast. 204:109-127. 1988
Structural-analysis of polymers of sickle-cell hemoglobin .1. Sickle hemoglobin fibers. 199:315-331. 1988
Structural-analysis of polymers of sickle-cell hemoglobin .2. Sickle hemoglobin macrofibers. 199:333-348. 1988
Three-dimensional structure of rabbit liver [Cd7]metallothionein-2a in aqueous solution determined by nuclear magnetic resonance. 201:637-657. 1988
Assignment of resonances in the h-1 nuclear-magnetic-resonance spectrum of the carbon-monoxide complex of human-hemoglobin alpha-chains. 194:329-339. 1987
Assignment of resonances in the h-1 nuclear-magnetic-resonance spectrum of the carbon-monoxide complex of sperm whale myoglobin by phase-sensitive two-dimensional techniques. 194:313-327. 1987
Metal coordination in rat-liver metallothionein-2 prepared with or without reconstitution of the metal-clusters, and comparison with rabbit liver metallothionein-2. 196:711-719. 1987
Protein structures in solution by nuclear-magnetic-resonance and distance geometry - the polypeptide fold of the basic pancreatic trypsin-inhibitor determined using 2 different algorithms, disgeo and disman. 196:611-639. 1987
Complete sequence-specific h-1 nuclear-magnetic-resonance assignments for the alpha-amylase polypeptide inhibitor tendamistat from streptomyces-tendae. 192:869-890. 1986
H-1-nuclear magnetic-resonance assignments for d-(gcattaatgc)2 using experimental refinements of established procedures. 190:439-453. 1986
Nonenzymatic template-directed synthesis on RNA random copolymers - Poly(C, G) templates. 188:433-441. 1986
An evaluation of the combined use of nuclear magnetic-resonance and distance geometry for the determination of protein conformations in solution. 182:281-294. 1985
Binding of an antitumor drug to DNA netropsin and C-G-C-G-A-A-T-T-BrC-G-C-G. 183:553-563. 1985
Crystal-structure of azotobacter cytochrome-c5 at 2.5-a resolution. 184:279-295. 1985
Messenger-rna from staphylococcus-aureus that specifies "macrolide-lincosamide-streptogramin resistance - demonstration of its conformations and of the leader peptide it encodes. 185:769-780. 1985
Solution conformation of proteinase inhibitor-iia from bull seminal plasma by h-1 nuclear magnetic-resonance and distance geometry. 182:295-315. 1985
Structural relationship of human interferon-alpha genes and pseudogenes. 185:227-260. 1985
Calibration of the angular-dependence of the amide proton-c-alpha proton coupling-constants, 3jhn-alpha, in a globular protein - use of 3jhn-alpha for identification of helical secondary structure. 180:741-751. 1984
Neutron-scattering studies of subcomponent clq of 1st component cl of human-complement and its association with subunit clr2cls2 within cl. 179:547-557. 1984
Non-enzymatic template-directed synthesis on RNA random copolymers - Poly(C,U) templates. 176:279-306. 1984
Polypeptide secondary structure determination by nuclear magnetic-resonance observation of short proton proton distances. 180:715-740. 1984
Secondary structure in the solution conformation of the proteinase inhibitor-iia from bull seminal plasma by nuclear magnetic-resonance. 173:341-359. 1984
Template-directed synthesis on the pentanucleotide CpCpGpCpC. 178:669-676. 1984
Assignment of the h-1 nuclear magnetic-resonance spectrum of the proteinase inhibitor-iia from bull seminal plasma by two-dimensional nuclear magnetic-resonance at 500 mhz. 166:641-667. 1983
Assignment of the h-1 nuclear magnetic-resonance spectrum of the trypsin-inhibitor homologue-k from dendroaspis-polylepis-polylepis - 2 dimensional nuclear magnetic-resonance at 360 and 500 mhz. 163:623-646. 1983
Characterization of the proteinase inhibitor-iia from bull seminal plasma by h-1 nuclear magnetic-resonance - stability, amide proton-exchange and mobility of aromatic residues. 166:631-640. 1983
Conformation of glucagon in a lipid water interphase by h-1 nuclear magnetic-resonance. 169:921-948. 1983
Preliminary structural comparison of the proteinase isoinhibitors-iia and isoinhibitor-iib from bull seminal plasma based on individual assignments of the h-1 nuclear magnetic-resonance spectra by two-dimensional nuclear magnetic-resonance at 500 mhz. 166:669-676. 1983
Pseudo-structures for the 20 common amino-acids for use in studies of protein conformations by measurements of intramolecular proton proton distance constraints with nuclear magnetic-resonance. 169:949-961. 1983
Structure of a t=1 aggregate of alfalfa mosaic-virus coat protein seen at 4.5-a resolution. 167:873-890. 1983
Structure of tomato busy stunt virus. IV. The virus particle at 2.9 A resolution. 171:61-93. 1983
Amide proton-exchange and surface conformation of the basic pancreatic trypsin-inhibitor in solution - studies with two-dimensional nuclear magnetic-resonance. 160:343-361. 1982
Assignment of the h-1 nuclear magnetic-resonance spectrum of the trypsin inhibitor-e from dendroaspis-polylepis-polylepis two-dimensional nuclear magnetic-resonance at 500 mhz. 159:323-351. 1982
Determination and analysis of the 2A structure of copper, zinc superoxide-dismutase. 160:181-217. 1982
Distribution of rna and protein in crystalline eukaryotic ribosomes. 156:431-448. 1982
Iron-sulfur clusters and protein-structure of azotobacter ferredoxin at 2.0 a resolution. 158:73-109. 1982
Sequential resonance assignments as a basis for determination of spatial protein structures by high-resolution proton nuclear magnetic-resonance. 155:311-319. 1982
Sequential resonance assignments in protein h-1 nuclear magnetic-resonance spectra - basic pancreatic trypsin-inhibitor. 155:347-366. 1982
Sequential resonance assignments in protein h-1 nuclear magnetic-resonance spectra - computation of sterically allowed proton proton distances and statistical-analysis of proton proton distances in single-crystal protein conformations. 155:321-346. 1982
Sequential resonance assignments in protein h-1 nuclear magnetic-resonance spectra - glucagon bound to perdeuterated dodecylphosphocholine micelles. 155:367-388. 1982
Interactions of Qβ replicase with Qβ RNA. 153:631-660. 1981
Conformational transition from trypsinogen to trypsin - h-1 nuclear magnetic-resonance at 360 mhz and ring current calculations. 138:43-64. 1980
Neutron-diffraction analysis of the structure of rod photoreceptor-membranes in intact retinas. 137:315-348. 1980
Structure of lobster apo-d-glyceraldehyde-3-phosphate dehydrogenase at 3.0 a resolution. 138:859-872. 1980
Attachment of ribosome crystals to intracellular membranes. 132:69-84. 1979
Correlation between the amide proton-exchange rates and the denaturation temperatures in globular-proteins related to the basic pancreatic trypsin-inhibitor. 130:31-37. 1979
Escherichia coli ribosomes bind to non-initiator sites of Qβ RNA in the absence of formylmethionyl transfer RNA. 128:481-500. 1979
Kinetics of the exchange of individual amide protons in the basic pancreatic trypsin-inhibitor. 130:19-30. 1979
Nuclear magnetic-resonance of labile protons in the basic pancreatic trypsin-inhibitor. 130:1-18. 1979
Preparation and characterization of form-v DNA, the duplex DNA resulting from association of complementary, circular single-stranded-DNA. 131:21-40. 1979
Structural interpretation of the amide proton-exchange in the basic pancreatic trypsin-inhibitor and related proteins. 134:75-94. 1979
Two forms of isolated gap junctions. 135:451-464. 1979
Site-directed mutagenesis in DNA: generation of point mutations in cloned β globin complementary DNA at the positions corresponding to amino acids 121 to 123. 124:343-358. 1978
Site-directed mutations in initiator region of bacteriophage Qβ coat cistron and their effect on ribosome binding. 118:533-565. 1978
A guanosine to adenosine transition in the 3' terminal extracistronic region of bacteriophage Qβ RNA leading to loss of infectivity. 112:235-252. 1977
Isolation, characterization and structural implications of a nuclease-digested complex of aminoacyl transfer RNA and Escherichia coli elongation factor Tu. 114:451-458. 1977
Nano-variant rnas - nucleotide-sequence and interaction with bacteriophage qbeta replicase. 117:877-907. 1977
Packing of ribosomes in crystals from lizard lacerta-sicula. 114:491-506. 1977
Rapid accumulation and disappearance of plasma-membrane proteins during development of wild-type and mutant strains of dictyostelium-discoideum. 116:469-488. 1977
Developmentally regulated proteins of plasma-membrane of dictyostelium-discoideum - carbohydrate-binding protein. 100:157-178. 1976
Physical mapping of qbeta replicase binding-sites on qbeta rna. 101:367-377. 1976
Purification of globin messenger-rna from dimethylsulfoxide-induced friend cells and detection of a putative globin messenger-rna precursor. 106:1061-1075. 1976
Studies of histidine residues of triose phosphate isomerase by proton magnetic-resonance and x-ray crystallography. 100:319-343. 1976
Studies on the mechanism of enzymatic DNA elongation by Escherichia coli DNA polymerase II. 103:61-76. 1976
Beef liver catalase structure - interpretation of electron micrographs. 98:235-242. 1975
Interaction of polyamines with fragments and whole molecules of yeast phenylalanine-specific transfer RNA. 93:323-329. 1975
Molecular structure determination by electron microscopy of unstained crystalline specimens. 94:425-440. 1975
A new approach to the isolation of rna-DNA hybrids and its application to the quantitative determination of labeled tumor virus rna. 86:373-396. 1974
Electron microscopy of the stacked disk aggregate of tobacco mosaic virus protein. Ii. The influence of electron irradiation of the stain distribution. 87:657-670. 1974
Electron microscopy of the stacked disk aggregate of tobacco mosaic-virus protein: 1. Three-dimensional image reconstruction. 87:641-650. 1974
Interaction of manganese with fragments, complementary fragment recombinations, and whole molecules of yeast phenylalanine specific transfer RNA. 86:601-620. 1974
Photo-induced joining of a transfer RNA with its cognate aminoacyl-transfer RNA synthetase. 84:503-513. 1974
Relaxation spectra of the iron spin transition in methemoglobin. 89:505-510. 1974
Site-directed mutagenesis: generation of an extracistronic mutation in bacteriophage Qβ RNA. 89:255-272. 1974
Appearance of virus-specific DNA in mammalian cells following transformation by rous sarcoma virus. 74:613-626. 1973
Isolation and characterization of plasma membrane associated immunoglobulin from cultured human diploid lymphocytes. 76:485-502. 1973
Physical properties of cytoplasmic membrane-associated DNA. 78:43-56. 1973
Resynchronization of rna synthesis by coliphage qbeta replicase at an internal site of the rna template. 76:271-284. 1973
An immunological study of the fates of nuclear and nucleolar macromolecules during the cell cycle. 68:107-114. 1972
Structural investigations of modified hemoglobins by nuclear magnetic resonance spectroscopy. 63:477-482. 1972
Nuclear magnetic resonance determination of ligand-induced conformational changes in myoglobin. 53:143-157. 1970
Proton magnetic resonance studies of cyanoferrihemoglobins from different species. 49:197-202. 1970
Conformational energies and configurational statistics of copolypeptides containing L-proline. 34:105-120. 1968
Isolation and characterization of a hemagglutinin from limulus polyphemus. 32:453-465. 1968
Peptide maps of rabbit γG-immunoglobulin heavy chains controlled by allelic genes. 16:328-333. 1966
Peptide differences of rabbit γG-immunoglobulin light chains controlled by allelic genes. 11:713-721. 1965

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