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articles

  • Sequencing and Structure Probing of Long RNAs Using MarathonRT: A Next-Generation Reverse Transcriptase.  432:3338-3352. 2020
  • Diverse antibody responses to conserved structural motifs in plasmodium falciparum circumsporozoite protein.  432:1048-1063. 2020
  • SrmB rescues trapped ribosome assembly intermediates.  432:978-990. 2020
  • SARAF luminal domain structure reveals a novel domain-swapped β-sandwich fold important for SOCE modulation.  431:2869-2883. 2019
  • Protein and glycan mimicry in HIV vaccine design.  431:2223-2247. 2019
  • Fluorescent trimeric hemagglutinins reveal multivalent receptor binding properties.  431:842-856. 2019
  • A molecular target for an alcohol chain-length cutoff.  431:196-209. 2019
  • A novel polar core and weakly fixed C-tail in squid arrestin provide new insight into interaction with rhodopsin.  430:4102-4118. 2018
  • A sortase a programmable phage display format for improved panning of Fab antibody libraries.  430:4387-4400. 2018
  • From atoms to cells: using mesoscale landscapes to construct visual narratives.  430:3954-3968. 2018
  • Molecular illustration in research and education: past, present, and future.  430:3969-3981. 2018
  • Perspectives on structural molecular biology visualization: from past to present.  430:3997-4012. 2018
  • Revised crystal structure of human adenovirus reveals the limits on protein IX quasi-equivalence and on analyzing large macromolecular complexes.  430:4132-4141. 2018
  • A proteomic variant approach (ProVarA) for personalized medicine of inherited and somatic disease.  430:2951-2973. 2018
  • Expanding the Paradigm: Intrinsically Disordered Proteins and Allosteric Regulation.  430:2309-2320. 2018
  • Effect of tRNA on the maturation of HIV-1 reverse transcriptase.  430:1891-1900. 2018
  • A survey of DDX21 activity during Rev/RRE complex formation.  430:537-553. 2018
  • Nucleotide binding to ARL2 in the TBCD∙ARL2∙β-tubulin complex drives conformational changes in β-tubulin.  429:3696-3716. 2017
  • Mining naive rabbit antibody repertoires by phage display for monoclonal antibodies of therapeutic utility.  429:2954-2973. 2017
  • The role of hexon protein as a molecular mold in patterning the protein IX organization in human adenoviruses.  429:2747-2751. 2017
  • A perspective on the structural and functional constraints for immune evasion: insights from influenza virus.  429:2694-2709. 2017
  • Marking the milestones in structural biology.  429:2591-2593. 2017
  • Structural foundations of RNA silencing by Argonaute.  429:2619-2639. 2017
  • Architecture of the flagellar switch complex of Escherichia coli: conformational plasticity of FliG and implications for adaptive remodeling.  429:1305-1320. 2017
  • A DEAD-box helicase mediates an RNA structural transition in the HIV-1 Rev response element.  429:697-714. 2017
  • Backbone engineering within a latent β-hairpin structure to design inhibitors of polyglutamine amyloid formation.  429:308-323. 2017
  • The kinetic stability of a full-length antibody light chain dimer determines whether endoproteolysis can release amyloidogenic variable domains.  428:4280-4297. 2016
  • Design Principles for SuCESsFul Biosensors: Specific Fluorophore/Analyte Binding and Minimization of Fluorophore/Scaffold Interactions.  428:4228-4241. 2016
  • S-Nitrosylation induces structural and dynamical changes in a rhodanese family protein.  428:3737-3751. 2016
  • Challenges in structural approaches to cell modeling.  428:2943-2964. 2016
  • Directional phosphorylation and nuclear transport of the splicing factor SRSF1 is regulated by an RNA recognition motif.  428:2430-2445. 2016
  • High-resolution mapping of the folding transition state of a WW domain.  428:1617-1636. 2016
  • DIx5 homeodomain:DNA complex: structure, binding and effect of mutations related to split hand and foot malformation syndrome.  428:1130-1141. 2016
  • Monitoring ligand-induced protein ordering in drug discovery.  428:1290-1303. 2016
  • Deciphering complexity in molecular biophysics with single-molecule resolution.  428:301-307. 2016
  • A substrate mimic allows high-throughput assay of the FabA protein and consequently the identification of a novel inhibitor of pseudomonas aeruginosa FabA.  428:108-120. 2016
  • Conformational transitions that enable histidine kinase autophosphorylation and receptor array integration.  427:3890-3907. 2015
  • Architecture of the complex formed by large and small terminase subunits from bacteriophage P22.  427:3285-3299. 2015
  • ClickSeq: Fragmentation-free next-generation sequencing via click ligation of adaptors to stochastically terminated 3 '-azido cDNAs.  427:2610-2616. 2015
  • Structure of hepatitis C virus envelope glycoprotein E1 antigenic site 314-324 in complex with antibody IGH526.  427:2617-2628. 2015
  • The Pex1/Pex6 complex is a heterohexameric AAA+ motor with alternating and highly coordinated subunits.  427:1375-1388. 2015
  • Assembly states of FliM and FliG within the flagellar switch complex.  427:867-886. 2015
  • The high-risk HPV16 E7 oncoprotein mediates interaction between the transcriptional coactivator CBP and the retinoblastoma protein pRb.  426:4030-4048. 2014
  • DNA recognition by a σ(54) transcriptional activator from Aquifex aeolicus.  426:3553-3568. 2014
  • In silico derived small molecules bind the filovirus VP35 protein and inhibit its polymerase cofactor activity.  426:2045-2058. 2014
  • The histone H4 tail regulates the conformation of the ATP-binding pocket in the SNF2h chromatin remodeling enzyme.  426:2034-2044. 2014
  • The cleaved N-terminus of pVI binds peripentonal hexons in mature adenovirus.  426:1971-1979. 2014
  • Structures of a bifunctional cell wall hydrolase CwlT containing a novel bacterial lysozyme and an NlpC/P60 DL-endopeptidase.  426:169-184. 2014
  • The N-terminal sequence of tyrosine hydroxylase is a conformationally versatile motif that binds 14-3-3 proteins and membranes.  426:150-168. 2014
  • NMR structures of α-proteobacterial ATPase-regulating ζ-subunits.  426:2547-2553. 2014
  • Cryo-EM structures of the actin:tropomyosin filament reveal the mechanism for the transition from C- to M-state.  425:4544-4555. 2013
  • Malachite green mediates homodimerization of antibody VL domains to form a fluorescent ternary complex with singular symmetric interfaces.  425:4595-4613. 2013
  • The disordered C-terminal domain of human DNA glycosylase NEIL1 contributes to its stability via intramolecular interactions.  425:2359-2371. 2013
  • Hidden allostery in human glutathione transferase p1-1 unveiled by unnatural amino acid substitutions and inhibition studies.  425:1509-1514. 2013
  • Dissecting the molecular mechanism of IVIg therapy: the interaction between serum IgG and DC-SIGN is independent of antibody glycoform or Fc domain.  425:1253-1258. 2013
  • Dispersed sites of HIV Vif-dependent polyubiquitination in the DNA deaminase APOBEC3F.  425:1172-1182. 2013
  • β-hairpin-mediated nucleation of polyglutamine amyloid formation.  425:1183-1197. 2013
  • Localized structural fluctuations promote amyloidogenic conformations in transthyretin.  425:977-988. 2013
  • Architecture of the Soluble Receptor Aer2 Indicates an In-Line Mechanism for PAS and HAMP Domain Signaling.  425:886-901. 2013
  • Long-range effects and functional consequences of stabilizing mutations in the ankyrin repeat domain of IκBα.  425:902-913. 2013
  • A protein.protein interaction platform involved in recruitment of GLD-3 to the FBF.Fem-3 mRNA complex.  425:738-754. 2013
  • Biochemical characterization of the Caenorhabditis elegans FBF. CPB-1 translational regulation complex identifies conserved protein interaction hotspots.  425:725-737. 2013
  • Characterization of the ribosome biogenesis landscape in E. coli using quantitative mass spectrometry.  425:767-779. 2013
  • Structural mechanism of GAF-regulated sigma(54) activators from Aquifex aeolicus.  425:156-170. 2013
  • Structural analysis of the quaking homodimerization interface.  423:766-781. 2012
  • Prion protein mPrP[F175A](121-231): structure and stability in solution.  423:496-502. 2012
  • Gating movement of acetylcholine receptor caught by plunge-freezing.  422:617-634. 2012
  • Immature and mature human astrovirus: structure, conformational changes, and similarities to hepatitis E virus.  422:650-658. 2012
  • Structure-guided directed evolution of highly selective p450-based magnetic resonance imaging sensors for dopamine and serotonin.  422:245-262. 2012
  • A molecular history of the amyloidoses.  421:142-159. 2012
  • The transthyretin amyloidoses: from delineating the molecular mechanism of aggregation linked to pathology to a regulatory-agency-approved drug.  421:185-203. 2012
  • Selective deactivation of serum IgG: a general strategy for the enhancement of monoclonal antibody receptor interactions.  420:1-7. 2012
  • Structure of an essential type iv pilus biogenesis protein provides insights into pilus and type ii secretion systems.  419:110-124. 2012
  • The structure of the NXF2/NXT1 heterodimeric complex reveals the combined specificity and versatility of the NTF2-like fold.  415:649-665. 2012
  • The structure of Aquifex aeolicus ribosomal protein S8 reveals a unique subdomain that contributes to an extremely tight association with 16S rRNA.  415:489-502. 2012
  • Computational design of high-affinity epitope scaffolds by backbone grafting of a linear epitope.  415:175-192. 2012
  • DDX1 is an RNA-dependent ATPase involved in HIV-1 Rev function and virus replication.  415:61-74. 2012
  • The evolution of cefotaximase activity in the TEM β-lactamase.  415:205-220. 2012
  • The metavinculin tail domain directs constitutive interactions with raver1 and vinculin RNA.  422:697-704. 2012
  • Structure-based design of a protein immunogen that displays an hiv-1 gp41 neutralizing epitope.  414:460-476. 2011
  • Hotspot-centric de novo design of protein binders.  413:1047-1062. 2011
  • Systematic chromosomal deletion of bacterial ribosomal protein genes.  413:751-761. 2011
  • Structure of an enclosed dimer formed by the Drosophila period protein.  413:561-572. 2011
  • Light-induced conformational changes in full-length Arabidopsis thaliana cryptochrome.  413:128-137. 2011
  • Engineering GST M2-2 for high activity with indene 1,2-oxide and indication of an H-site residue sustaining catalytic promiscuity.  412:111-120. 2011
  • Consequences of stabilizing the natively disordered f helix for the folding pathway of apomyoglobin.  411:248-263. 2011
  • Dynamic interaction of hsp90 with its client protein p53.  411:158-173. 2011
  • Single-molecule studies reveal that dead box protein DDX1 promotes oligomerization of HIV-1 Rev on the Rev response element.  410:959-971. 2011
  • Accessory mutations maintain stability in drug-resistant HIV-1 protease.  410:756-760. 2011
  • Design of in vitro symmetric complexes and analysis by hybrid methods reveal mechanisms of HIV capsid assembly.  410:534-552. 2011
  • Design and characterization of epitope-scaffold immunogens that present the motavizumab epitope from respiratory syncytial virus.  409:853-866. 2011
  • Structural biology by mass spectrometry: mapping protein interaction surfaces of membrane receptor complexes with ICAT.  409:481-482. 2011
  • Dynamic conformational equilibria in the physiological function of the Bombyx mori pheromone-binding protein.  408:922-931. 2011
  • The evolution of catalytic function in the HIV-1 protease.  408:792-805. 2011
  • The prohead-i structure of bacteriophage hk97: Implications for scaffold-mediated control of particle assembly and maturation.  408:541-554. 2011
  • Site-specific coupling and sterically controlled formation of multimeric antibody fab fragments with unnatural amino acids.  406:595-603. 2011
  • The structure of the crispr-associated protein csa3 provides insight into the regulation of the crispr/cas system.  405:939-955. 2011
  • The rela nuclear localization signal folds upon binding to i kappa b alpha.  405:754-764. 2011
  • Molecular architecture and connectivity of the budding yeast Mtw1 kinetochore complex.  405:548-559. 2011
  • An RNA conformational switch regulates pre-18S rRNA cleavage.  405:3-17. 2011
  • Computational protein design using flexible backbone remodeling and resurfacing: case studies in structure-based antigen design.  405:284-297. 2011
  • Mechanism of binding site conformational switching in the CD44-hyaluronan protein-carbohydrate binding interaction.  406:631-647. 2011
  • Insights into substrate specificity of geranylgeranyl reductases revealed by the structure of digeranylgeranylglycerophospholipid reductase, an essential enzyme in the biosynthesis of archaeal membrane lipids.  404:403-417. 2010
  • Multiple sequence signals direct recognition and degradation of protein substrates by the AAA plus protease HslUV.  403:420-429. 2010
  • Quantitative proteomic analysis of ribosome assembly and turnover in vivo.  403:331-345. 2010
  • NMR Structure of the SARS-CoV Nonstructural Protein 7 in Solution at pH 6.5.  402:619-628. 2010
  • Disulfide bond stabilization of the hexameric capsomer of human immunodeficiency virus.  401:985-995. 2010
  • A novel quasi-species of glutathione transferase with high activity towards naturally occurring isothiocyanates evolves from promiscuous low-activity variants.  401:451-464. 2010
  • Crystal structure of fatty acid amide hydrolase bound to the carbamate inhibitor urb597: Discovery of a deacylating water molecule and insight into enzyme inactivation.  400:743-754. 2010
  • SARS coronavirus unique domain: three-domain molecular architecture in solution and RNA binding.  400:724-742. 2010
  • Tm0486 from the hyperthermophilic anaerobe thermotoga maritima is a thiamin-binding protein involved in response of the cell to oxidative conditions.  400:463-476. 2010
  • X-ray structures of the LXRα LBD in its homodimeric form and implications for heterodimer signaling.  399:120-132. 2010
  • Nmr solution structure and DNA-binding model of the DNA-binding domain of competence protein a.  398:248-263. 2010
  • The effect of ribosome assembly cofactors on in vitro 30S subunit reconstitution.  398:1-7. 2010
  • Crystal structure of the botulinum neurotoxin type G binding domain: insight into cell surface binding.  397:1287-1297. 2010
  • A single-domain llama antibody potently inhibits the enzymatic activity of botulinum neurotoxin by binding to the non-catalytic alpha-exosite binding region.  397:1106-1118. 2010
  • Backbone model of an aquareovirus virion by cryo-electron microscopy and bioinformatics.  397:852-863. 2010
  • Building and refining protein models within cryo-electron microscopy density maps based on homology modeling and multiscale structure refinement.  397:835-851. 2010
  • Crystal structure of the first eubacterial Mre11 nuclease reveals novel features that may discriminate substrates during DNA repair.  397:647-663. 2010
  • Generation and characterization of a chimeric rabbit/human Fab for co-crystallization of HIV-1 Rev.  397:697-708. 2010
  • A dynamic model of HIV integrase inhibition and drug resistance.  397:600-615. 2010
  • Hk97 maturation studied by crystallography and h/(2)h exchange reveals the structural basis for exothermic particle transitions.  397:560-574. 2010
  • Structural basis for featuring of steroid isomerase activity in alpha class glutathione transferases.  397:332-340. 2010
  • Surrobodies with functional tails.  397:352-360. 2010
  • Energetic frustration of apomyoglobin folding: Role of the b helix.  396:1319-1328. 2010
  • Crystal structure of CYP24A1, a mitochondrial cytochrome P450 involved in vitamin D metabolism.  396:441-451. 2010
  • Bacterial pleckstrin homology domains: A prokaryotic origin for the PH domain.  396:31-46. 2010
  • An enhanced system for unnatural amino acid mutagenesis in E. coli.  395:361-374. 2010
  • Topological frustration in beta alpha-repeat proteins: sequence diversity modulates the conserved folding mechanisms of alpha/beta/alpha sandwich proteins.  398:332-350. 2010
  • Directed evolution of an enhanced and highly efficient foki cleavage domain for zinc finger nucleases.  400:96-107. 2010
  • Horse prion protein NMR structure and comparisons with related variants of the mouse prion protein.  400:121-128. 2010
  • Structural evaluation of potent NKT cell agonists: Implications for design of novel stimulatory ligands.  394:71-82. 2009
  • Illuminating solution responses of a LOV domain protein with photocoupled small-angle X-ray scattering.  393:909-919. 2009
  • The design and characterization of oligospecific antibodies for simultaneous targeting of multiple disease mediators..  393:672-692. 2009
  • Dynamics and stability in maturation of a T = 4 virus.  392:803-812. 2009
  • Structural and functional analysis of the globular head domain of p115 provides insight into membrane tethering.  391:26-41. 2009
  • p38alpha MAP kinase C-terminal domain binding pocket characterized by crystallographic and computational analyses.  391:1-11. 2009
  • Crystal structure of histidine phosphotransfer protein ShpA, an essential regulator of stalk biogenesis in Caulobacter crescentus.  390:686-698. 2009
  • Prion protein NMR structure from tammar wallaby (Macropus eugenii) shows that the beta2-alpha2 loop is modulated by long-range sequence effects.  389:833-845. 2009
  • Alternative exon 9-encoded relay domains affect more than one communication pathway in the Drosophila myosin head.  389:707-721. 2009
  • Efficient recovery of high-affinity antibodies from a single-chain fab yeast display library.  389:365-375. 2009
  • Interaction of the i kappa b alpha c-terminal pest sequence with nf-kappa b: Insights into the inhibition of nf-kappa b DNA binding by i kappa b alpha.  388:824-838. 2009
  • The determinants of stability and folding in evolutionarily diverged cytochromes c.  388:159-167. 2009
  • Carbohydrate and domain architecture of an immature antibody glycoform exhibiting enhanced effector functions.  387:1061-1066. 2009
  • Structural and motional contributions of the Bacillus subtilis ClpC N-domain to adaptor protein interactions.  387:639-652. 2009
  • Effect of Mg(2+) and Na(+) on the nucleic acid chaperone activity of HIV-1 nucleocapsid protein: implications for reverse transcription.  386:773-788. 2009
  • HIV-1 nucleocapsid protein switches the pathway of transactivation response element RNA/DNA annealing from loop-loop "kissing" to "zipper".  386:789-801. 2009
  • Superoxide dismutase from the eukaryotic thermophile alvinella pompejana: Structures, stability, mechanism, and insights into amyotrophic lateral sclerosis.  385:1534-1555. 2009
  • Insights from Xanthine and Uracil DNA Glycosylase Activities of Bacterial and Human SMUG1: Switching SMUG1 to UDG.  385:761-778. 2009
  • A structural basis for the regulatory inactivation of DnaA.  385:368-380. 2009
  • Crystal structures of protein phosphatase-1 bound to nodularin-R and tautomycin: a novel scaffold for structure-based drug design of serine/threonine phosphatase inhibitors.  385:11-21. 2009
  • Generation, affinity maturation, and characterization of a human anti-human NKG2D monoclonal antibody with dual antagonistic and agonistic activity.  384:1143-1156. 2008
  • Structure and regulatory mechanism of Aquifex aeolicus NtrC4: variability and evolution in bacterial transcriptional regulation.  384:1058-1075. 2008
  • The crystal structure of CD8 in complex with YTS156.7.7 Fab and interaction with other CD8 antibodies define the binding mode of CD8 alphabeta to MHC class I.  384:1190-1202. 2008
  • Assembly architecture and DNA binding of the bacteriophage P22 terminase small subunit.  383:494-501. 2008
  • NMR structure of the bank vole prion protein at 20 degrees c contains a structured loop of residues 165-171.  383:306-312. 2008
  • Structural insight into pH-induced conformational changes within the native human transthyretin tetramer.  382:1157-1167. 2008
  • Emergence of novel enzyme quasi-species depends on the substrate matrix.  382:136-153. 2008
  • Recent avian h5n1 viruses exhibit increased propensity for acquiring human receptor specificity.  381:1382-1394. 2008
  • Similarities and differences between frozen-hydrated, rigor acto-S1 complexes of insect flight and chicken skeletal muscles.  381:519-528. 2008
  • Structural basis of guanine nucleotide exchange mediated by the t-cell essential vav1.  380:828-843. 2008
  • Transfer of flexibility between ankyrin repeats in i kappa b alpha upon formation of the nf-kappa b complex.  380:917-931. 2008
  • Structural and biochemical characterization of the therapeutic anabaena variabilis phenylalanine ammonia lyase.  380:623-635. 2008
  • Autoinhibition of human dicer by its internal helicase domain.  380:237-243. 2008
  • Alternative relay domains of Drosophila melanogaster myosin differentially affect ATPase activity, in vitro motility, myofibril structure and muscle function.  379:443-456. 2008
  • Spatially directed assembly of a heterotetrameric Cre-Lox synapse restricts recombination specificity.  378:653-665. 2008
  • The kinetic and equilibrium molten globule intermediates of apoleghemoglobin differ in structure.  378:715-725. 2008
  • Crystal structure of Lsm3 octamer from Saccharomyces cerevisiae: Implications for Lsm ring organisation and recruitment.  377:1357-1371. 2008
  • Evolution of class-specific peptides targeting a hot spot of the Galphas subunit.  377:1406-1418. 2008
  • Crystal structures of mouse CD1d-iGb3 complex and its cognate v alpha 14 T cell receptor suggest a model for dual recognition of foreign and self glycolipids.  377:1104-1116. 2008
  • Visualisation of a kinesin-13 motor on microtubule end mimics.  377:647-654. 2008
  • Stabilization of the human β2-adrenergic receptor TM4-TM3-TM5 helix interface by mutagenesis of Glu122(3.41), a critical residue in GPCR structure.  376:1305-1319. 2008
  • Modulating catalytic activity by unnatural amino acid residues in a GSH-binding loop of GST P1-1.  376:811-826. 2008
  • Structural determinants of glutathione transferases with azathioprine activity identified by DNA shuffling of alpha class members.  375:1365-1379. 2008
  • Transcriptional stability of cultured cells upon prion infection.  375:1222-1233. 2008
  • Structure of antibody f425-b4e8 in complex with a v3 peptide reveals a new binding mode for hiv-1 neutralization.  375:969-978. 2008
  • NMR structure of the Escherichia coli type 1 pilus subunit FimF and its interactions with other pilus subunits.  375:752-763. 2008
  • Complex of a protective antibody with its ebola virus gp peptide epitope: Unusual features of a v lambda(x) light chain.  375:202-216. 2008
  • Subdomain competition, cooperativity, and topological frustration in the folding of CheY.  382:485-495. 2008
  • Structural basis of ligand binding and release in insect pheromone-binding proteins: NMR structure of Antheraea polyphemus PBP1 at pH 4.5.  373:811-819. 2007
  • Structural characterization of zinc-deficient human superoxide dismutase and implications for ALS.  373:877-890. 2007
  • Structure of the wilms tumor suppressor protein zinc finger domain bound to DNA.  372:1227-1245. 2007
  • Dynamic structure of retinylidene ligand of rhodopsin probed by molecular simulations.  372:906-917. 2007
  • The structure of isolated Synechococcus strain WH8102 carboxysomes as revealed by electron cryotomography.  372:764-773. 2007
  • Cold-adaptation in sea-water-borne signal proteins: sequence and NMR structure of the pheromone En-6 from the Antarctic ciliate Euplotes nobilii.  372:277-286. 2007
  • Inhibition of mammalian glycan biosynthesis produces non-self antigens for a broadly neutralising, HIV-1 specific antibody.  372:16-22. 2007
  • High-resolution electron microscopy of helical specimens: A fresh look at Tobacco Mosaic Virus.  371:812-835. 2007
  • An improved system for the generation and analysis of mutant proteins containing unnatural amino acids in Saccharomyces cerevisiae.  371:112-122. 2007
  • Comparison of the catalytic parameters and reaction specificities of a phage and an archaeal flap endonuclease.  371:34-48. 2007
  • Specific recognition of a DNA immunogen by its elicited antibody.  370:183-195. 2007
  • Galanthamine and non-competitive inhibitor binding to ACh-binding protein: evidence for a binding site on non-alpha-subunit interfaces of heteromeric neuronal nicotinic receptors.  369:895-901. 2007
  • Structural basis of DNA recognition by the alternative sigma-factor, sigma54.  369:1070-1078. 2007
  • Structure of a high-affinity "mimotope" peptide bound to HIV-1-neutralizing antibody b12 explains its inability to elicit gp120 cross-reactive antibodies.  369:696-709. 2007
  • Crystal structures of a quorum-quenching antibody.  368:1392-1402. 2007
  • Alternative S2 hinge regions of the myosin rod differentially affect muscle function, myofibril dimensions and myosin tail length.  367:1312-1329. 2007
  • Evolution of programmable zinc finger-recombinases with activity in human cells.  367:802-813. 2007
  • NMR structure and functional characterization of a human cancer-related nucleoside triphosphatase.  367:788-801. 2007
  • Maturation of shark single-domain (ignar) antibodies: Evidence for induced-fit binding.  367:358-372. 2007
  • Single-particle image reconstruction of a tetramer of hiv integrase bound to DNA.  366:286-294. 2007
  • Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10.  365:1533-1544. 2007
  • Domain interdependence in the biosynthetic assembly of CFTR.  365:981-994. 2007
  • Identification and characterization of single chain anti-cocaine catalytic antibodies.  365:722-731. 2007
  • Hydrophobic cooperativity as a mechanism for amyloid nucleation.  368:894-901. 2007
  • Embryonic neural inducing factor churchill is not a DNA-binding zinc finger protein: Solution structure reveals a solvent-exposed beta-sheet and zinc binuclear cluster.  371:1274-1289. 2007
  • In meso structure of the cobalamin transporter, btub, at 1.95 Å resolution.  364:716-734. 2006
  • Substrate recognition, protein dynamics, and iron-sulfur cluster in Pseudomonas aeruginosa adenosine 5'-phosphosulfate reductase.  364:152-169. 2006
  • Binding-induced stabilization and assembly of the phage P22 tail accessory factor gp4.  363:558-576. 2006
  • Solution structure of the Hdm2 C2H2C4 RING, a domain critical for ubiquitination of p53.  363:433-450. 2006
  • Structure of aart, a designed six-finger zinc finger peptide, bound to DNA.  363:405-421. 2006
  • Directed evolution of an anti-prion protein scfv fragment to an affinity of 1 pm and its structural interpretation.  363:75-97. 2006
  • Mechanistic studies of mini-TAR RNA/DNA annealing in the absence and presence of HIV-1 nucleocapsid protein.  363:244-261. 2006
  • Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1.  363:201-214. 2006
  • Pas domain allostery and light-induced conformational changes in photoactive yellow protein upon I-2 intermediate formation, probed with enhanced hydrogen/deuterium exchange mass spectrometry.  363:148-160. 2006
  • A structural perspective of the sequence variability within botulinum neurotoxin subtypes a1-a4.  362:733-742. 2006
  • The three-dimensional arcitecture of the EJC core.  360:743-749. 2006
  • Identification of the key LMO2-binding determinants on Ldb1.  359:66-75. 2006
  • A novel processive mechanism for DNA synthesis revealed by structure, modeling and mutagenesis of the accessory subunit of human mitochondrial DNA polymerase.  358:1229-1243. 2006
  • Crystal structure of the TCR co-receptor CD8 alpha alpha in complex with monoclonal antibody YTS 105.18 Fab fragment at 2.88 A resolution.  358:347-354. 2006
  • Antibody elbow angles are influenced by their light chain class.  357:1566-1574. 2006
  • Room to move: Crystallizing membrane proteins in swollen lipidic mesophases.  357:1605-1618. 2006
  • Amyloid formation by recombinant full-length prion proteins in phospholipid bicelle solutions.  357:833-841. 2006
  • Induced fit and "lock and key" recognition of 5s RNA by zinc fingers of transcription factor IIIA.  357:275-291. 2006
  • Structural insights into the mechanisms of drug resistance in HIV-1 protease NL4-3.  356:967-981. 2006
  • GTP-dependent formation of a ribonucleoprotein subcomplex required for ribosome biogenesis.  356:432-443. 2006
  • Retention of misfolded mutant transthyretin by the chaperone BiP/GRP78 mitigates amyloidogenesis.  356:469-482. 2006
  • Structural determinants of rotavirus subgroup specificity mapped by cryo-electron microscopy.  356:209-221. 2006
  • Glycan microarray analysis of the hemagglutinins from modern and pandemic influenza viruses reveals different receptor specificities.  355:1143-1155. 2006
  • Structural basis for cooperative transcription factor binding to the cbp coactivator.  355:1005-1013. 2006
  • Environmentally controlled invasion of cancer cells by engineered bacteria.  355:619-627. 2006
  • Structure of the Escherichia coli quorum sensing protein SdiA: Activation of the folding switch by acyl homoserine lactones.  355:262-273. 2006
  • Identification of native and non-native structure in kinetic folding intermediates of apomyoglobin.  355:139-156. 2006
  • Structural basis of the suppressed catalytic activity of wild-type human glutathione transferase T1-1 compared to its W234R mutant.  355:96-105. 2006
  • Crystal structure of viral macrophage inflammatory protein i encoded by kaposi's sarcoma-associated herpesvirus at 1.7 a.  352:1019-1028. 2005
  • High affinity targets of protein kinase inhibitors have similar residues at the positions energetically important for binding.  352:1134-1156. 2005
  • Structure of a loose dimer: an intermediate in nitric oxide synthase assembly.  352:932-940. 2005
  • Cooperative reorganization of a 420 subunit virus capsid.  352:723-735. 2005
  • Directed evolution and identification of control regions of ColE1 plasmid replication origins using only nucleotide deletions.  351:763-775. 2005
  • Solution structure of the n-terminal zinc fingers of the xenopus laevis double-stranded rna-binding protein zfa.  351:718-730. 2005
  • Composition and structure of the 80S ribosome from the green alga Chlamydomonas reinhardtii: 80S ribosomes are conserved in plants and animals.  351:266-279. 2005
  • RNA helical packing in solution: NMR structure of a 30 kDa GAAA tetraloop-receptor complex.  351:371-382. 2005
  • Sequence determinants of a protein folding pathway.  351:383-392. 2005
  • The binding interface between Bacillus stearothermophilus ribosomal protein S15 and its 5 '-translational operator mRNA.  351:280-290. 2005
  • Ultra-potent antibodies against respiratory syncytial virus: effects of binding kinetics and binding valence on viral neutralization.  350:126-144. 2005
  • Role of an active site adenine in hairpin ribozyme catalysis.  349:989-1010. 2005
  • Molecular basis for the specificity of p27 toward cyclin-dependent kinases that regulate cell division.  349:764-773. 2005
  • Cryoem structure at 9 Å resolution of an adenovirus vector targeted to hematopoietic cells.  349:526-537. 2005
  • Kinetic stabilization of the native state by protein engineering: Implications for inhibition of transthyretin amyloidogenesis.  347:841-854. 2005
  • Solution structure and dynamics of LuxU from Vibrio harveyi, a phosphotransferase protein involved in bacterial quorum sensing.  347:297-307. 2005
  • Refined structure of the nicotinic acetylcholine receptor at 4 Å resolution.  346:967-989. 2005
  • Structures of the agouti signaling protein.  346:1059-1070. 2005
  • The structure of the neurotoxin-associated protein HA33/A from Clostridium botulinum suggests a reoccurring beta-trefoil fold in the progenitor toxin complex.  346:1083-1093. 2005
  • Conformational diversity in nad(h) and interacting transhydrogenase nicotinamide nucleotide binding domains.  346:617-629. 2005
  • Shape-specific nucleotide binding of single-stranded RNA by the GLD-1 STAR domain.  346:91-104. 2005
  • Assembly of acanthamoeba myosin-ii minifilaments. Model of anti-parallel dimers based on em and x-ray diffraction of 2d and 3d crystals.  345:363-373. 2005
  • Nucleosomes in solution exist as a mixture of twist-defect states.  345:103-114. 2005
  • Crystal structure of mouse triggering receptor expressed on myeloid cells 1 (trem-1) at 1.76 Å.  344:1175-1181. 2004
  • Crystal structure of the spindle assembly checkpoint protein Bub3.  344:885-892. 2004
  • Ligand-induced conformational changes in the bacillus subtilis chemoreceptor mcpb determined by disulfide crosslinking in vivo.  344:919-928. 2004
  • Protein biophysical properties that correlate with crystallization success in thermotoga maritima: Maximum clustering strategy for structural genomics.  344:977-991. 2004
  • Conformational states of cytochrome p450cam revealed by trapping of synthetic molecular wires.  344:455-469. 2004
  • RNA tertiary structure and cooperative assembly of a large ribonucleoprotein complex.  344:395-407. 2004
  • Structure/function studies on a S-adenosyl-(L)-methionine-dependent uroporphyrinogen III C methyltransferase (SUMT), a key regulatory enzyme of tetrapyrrole biosynthesis.  344:419-433. 2004
  • The origin of enantioselectivity in aldolase antibodies: crystal structure, site-directed mutagenesis, and computational analysis.  343:1269-1280. 2004
  • Analysis of the class i aldolase binding site architecture based on the crystal structure of 2-deoxyribose-5-phosphate aldolase at 0.99 Å resolution.  343:1019-1034. 2004
  • Zz domain of cbp: An unusual zinc finger fold in a protein interaction module.  343:1081-1093. 2004
  • Conversion of a mechanosensitive channel protein from a membrane-embedded to a water-soluble form by covalent modification with amphiphiles.  343:747-758. 2004
  • Helical shifts generate two distinct conformers in the atomic resolution structure of the CheA phosphotransferase domain from Thermotoga maritima.  341:1283-1294. 2004
  • The zinc-dependent redox switch domain of the chaperone hsp33 has a novel fold.  341:893-899. 2004
  • In vivo selection of combinatorial libraries and designed affinity maturation of polydactyl zinc finger transcription factors for icam-1 provides new insights into gene regulation.  341:635-649. 2004
  • Structural characterization of unfolded states of apomyoglobin using residual dipolar couplings.  340:1131-1142. 2004
  • Crystal structure of the Drosophila peptidoglycan recognition protein (PGRP)-SA at 1.56 A resolution.  340:909-917. 2004
  • Evidence that a local refolding event triggers maturation of hk97 bacteriophage capsid.  340:419-433. 2004
  • Promoter-targeted phage display selections with preassembled synthetic zinc finger libraries for endogenous gene regulation.  340:599-613. 2004
  • Role of an active site guanine in hairpin ribozyme catalysis probed by exogenous nucleobase rescue.  340:233-251. 2004
  • Differential arrangements of conserved building blocks among homologs of the rad50/mre11 DNA repair protein complex.  339:937-949. 2004
  • Solution structure of the kix domain of cbp bound to the transactivation domain of c-myb.  337:521-534. 2004
  • NMR structure of the integral membrane protein OmpX.  336:1211-1221. 2004
  • Thermodynamic dissection of the polymerizing and editing modes of a DNA polymerase.  336:673-693. 2004
  • Evolution of aldolase antibodies in vitro: Correlation of catalytic activity and reaction-based selection.  335:1007-1018. 2004
  • The rad50 signature motif: Essential to atp binding and biological function.  335:937-951. 2004
  • Improved breadth and potency of an hiv-1-neutralizing human single-chain antibody by random mutagenesis and sequential antigen panning.  335:209-219. 2004
  • Crystal structure of human triggering receptor expressed on myeloid cells 1 (TREM-1) at 1.47 A.  342:1237-1248. 2004
  • The refined structure of a protein catenane: The hk97 bacteriophage capsid at 3.44 Å resolution.  334:885-899. 2003
  • Sequence, structure and energetic determinants of phosphopeptide selectivity of SH2 domains.  334:823-841. 2003
  • Structure-based active site profiles for genome analysis and functional family subclassification.  334:387-401. 2003
  • Improved Gō-like models demonstrate the robustness of protein folding mechanisms towards non-native interactions.  334:309-325. 2003
  • Role of the b helix in early folding events in apomyoglobin: Evidence from site-directed mutagenesis for native-like long range interactions.  334:293-307. 2003
  • Gelsolin domain 2 Ca2+ affinity determines susceptibility to furin proteolysis and familial amyloidosis of finnish type.  334:119-127. 2003
  • Cell transformation by the v-myc oncogene abrogates c-Myc/Max-mediated suppression of a C/EBP beta-dependent lipocalin gene.  333:33-46. 2003
  • A humanized aldolase antibody for selective chemotherapy and adaptor immunotherapy.  332:889-899. 2003
  • Structural basis for recognition and catalysis by the bifunctional dctp deaminase and dutpase from methanococcus jannaschii.  331:885-896. 2003
  • Structural plasticity and the evolution of antibody affinity and specificity.  330:651-656. 2003
  • Structure analysis of peptide deformylases from Streptococcus pneumoniae, Staphylococcus aureus, Thermotoga maritima and Pseudomonas aeruginosa: Snapshots of the oxygen sensitivity of peptide deformylase.  330:309-321. 2003
  • Structure and reactivity of an asymmetric complex between hslv and i-domain deleted hslu, a prokaryotic homolog of the eukaryotic proteasome.  330:185-195. 2003
  • Structural basis for antibody catalysis of a cationic cyclization reaction.  329:69-83. 2003
  • Folding of a beta-sheet protein monitored by real-time NMR spectroscopy.  328:1161-1171. 2003
  • Hydration and packing are crucial to amyloidogenesis as revealed by pressure studies on transthyretin variants that either protect or worsen amyloid disease.  328:963-974. 2003
  • Monomeric complex of human orphan estrogen related receptor-2 with DNA: A pseudo-dimer interface mediates extended half-site recognition.  327:819-832. 2003
  • Thermodynamics of a designed protein catenane.  327:537-548. 2003
  • NMR structure of the human doppel protein.  326:1549-1557. 2003
  • Crystal structure of MHC class II I-Ab in complex with a human CLIP peptide: prediction of an I-Ab peptide-binding motif.  326:1157-1174. 2003
  • Inherent protein structural flexibility at the RNA-binding interface of L30e.  326:999-1004. 2003
  • Conformation of prpc on the cell surface as probed by antibodies.  326:475-483. 2003
  • Crystal structures of nucleosome core particles in complex with minor groove DNA-binding ligands.  326:371-380. 2003
  • Nmr structure of a variant human prion protein with two disulfide bridges.  326:225-234. 2003
  • Rabbit immune repertoires as sources for therapeutic monoclonal antibodies: the impact of kappa allotype-correlated variation in cysteine content on antibody libraries selected by phage display.  325:325-335. 2003
  • ALS mutants of human superoxide dismutase form fibrous aggregates via framework destabilization.  332:601-615. 2003
  • Crystal structures of two rat mhc class ia (rt1-a) molecules that are associated differentially with peptide transporter alleles tap-a and tap-b.  324:975-990. 2002
  • A general method to quantify quasi-equivalence in icosahedral viruses.  324:723-737. 2002
  • Insights into Lou Gehrig's disease from the structure and instability of the A4V mutant of human Cu,Zn superoxide dismutase.  324:247-256. 2002
  • Mapping long-range contacts in a highly unfolded protein.  322:655-662. 2002
  • Nmr structures of 36 and 73-residue fragments of the calreticulin p-domain.  322:773-784. 2002
  • The apomyoglobin folding pathway revisited: Structural heterogeneity in the kinetic burst phase intermediate.  322:483-489. 2002
  • Blocking transcription through a nucleosome with synthetic DNA ligands.  321:249-263. 2002
  • Native state hydrogen exchange study of suppressor and pathogenic variants of transthyretin.  320:821-832. 2002
  • Structural basis for mobility in the 1.1 Å crystal structure of the ng domain of thermus aquaticus ffh.  320:783-799. 2002
  • Structural comparison of bacterial and human iron-dependent phenylalanine hydroxylases: Similar fold, different stability and reaction rates.  320:645-661. 2002
  • High pressure NMR reveals that apomyoglobin is an equilibrium mixture from the native to the unfolded.  320:311-319. 2002
  • Activation of the nicotinic acetylcholine receptor involves a switch in conformation of the a subunits.  319:1165-1176. 2002
  • The effects of ionic strength on protein stability: the cold shock protein family.  319:541-554. 2002
  • Contrasting IgG structures reveal extreme asymmetry and flexibility.  319:9-18. 2002
  • Protein NMR structure determination with automated noe assignment using the new software candid and the torsion angle dynamics algorithm dyana.  319:209-227. 2002
  • Crystal structure of hsiuv complexed with a vinyl sulfone inhibitor: Corroboration of a proposed mechanism of allosteric activation of hsiv by hsiu.  318:779-785. 2002
  • The structure of apo human glutamate dehydrogenase details subunit communication and allostery.  318:765-777. 2002
  • An ensemble of theta class glutathione transferases with novel catalytic properties generated by stochastic recombination of fragments of two mammalian enzymes.  318:59-70. 2002
  • On the role of electrostatic interactions in the design of protein-protein interfaces.  318:161-177. 2002
  • Base flexibility in HIV-2 TAR RNA mapped by solution (15)N, (13)C NMR relaxation.  317:263-278. 2002
  • Hybridization of alpha class subunits generating a functional glutathione transferase A1-4 heterodimer.  316:395-406. 2002
  • Artificial protein cavities as specific ligand-binding templates: characterization of an engineered heterocyclic cation-binding site that preserves the evolved specificity of the parent protein.  315:845-857. 2002
  • The crystal structures of phosphopantetheine adenylyltransferase with bound substrates reveal the enzyme's catalytic mechanism.  315:487-495. 2002
  • Structure and activity of a thermostable thymine-DNA glycosylase: Evidence for base twisting to remove mismatched normal DNA bases.  315:373-384. 2002
  • Crystal structure of a non-canonical high affinity peptide complexed with MHC class I: a novel use of alternative anchors.  318:1307-1316. 2002
  • Crystal structure of a non-canonical low-affinity peptide complexed with MHC class I: a new approach for vaccine design.  318:1293-1305. 2002
  • Binding of neural cell adhesion molecules (n-cams) to the cellular prion protein.  314:1209-1225. 2001
  • Localization of membrane permeabilization and receptor binding sites on the vp4 hemagglutinin of rotavirus: Implications for cell entry.  314:985-992. 2001
  • Recognition templates for predicting adenylate-binding sites in proteins.  314:1245-1255. 2001
  • Refined crystallographic structure of pseudomonas aeruginosa exotoxin a and its implications for the molecular mechanism of toxicity.  314:823-837. 2001
  • Interaction of the Bacillus stearothermophilus ribosomal protein S15 with its 5 '-translational operator mRNA.  314:413-422. 2001
  • Crystal structure of an isolated V(alpha) domain of the 2C T-cell receptor.  314:1-8. 2001
  • Structural basis for a disfavored elimination reaction in catalytic antibody 1D4.  314:93-102. 2001
  • Nmr structure of the euplotes raikovi pheromone er-23 and identification of its five disulfide bonds.  313:923-931. 2001
  • Uba domains mediate protein-protein interactions between two DNA damage-inducible proteins.  313:955-963. 2001
  • Central domain assembly: thermodynamics and kinetics of S6 and S18 binding to an S15-RNA complex.  313:35-48. 2001
  • Analysis of rapid, large-scale protein quaternary structural changes: Time-resolved x-ray solution scattering of nudaurelia capensis omega virus (n omega v) maturation.  311:803-814. 2001
  • Structure and mechanism of the ruvb holliday junction branch migration motor.  311:297-310. 2001
  • The folding mechanism of a beta-sheet: the WW domain.  311:373-393. 2001
  • Crystal structure of a cocaine-binding antibody.  311:9-15. 2001
  • Solution structure of the third immunoglobulin domain of the neural cell adhesion molecule N-CAM: can solution studies define the mechanism of homophilic binding?.  311:161-172. 2001
  • Solution structure of Escherichia coli glutaredoxin-2 shows similarity to mammalian glutathione-S-transferases.  310:907-918. 2001
  • Hairpin ribozymes with four-way helical junctions mediate intracellular RNA ligation.  309:893-902. 2001
  • Sequence-specific recognition of DNA in the nucleosome by pyrrole-imidazole polyamides.  309:615-629. 2001
  • Structure, function, and dynamics of the dimerization and DNA-binding domain of oncogenic transcription factor v-Myc.  307:1395-1410. 2001
  • Expanding the genetic code: selection of efficient suppressors of four-base codons and identification of "shifty" four-base codons with a library approach in Escherichia coli.  307:755-769. 2001
  • Structural biochemistry of a type 2 rnase h: Rna primer recognition and removal during DNA replication.  307:541-556. 2001
  • Concerted kinetic folding of a multidomain ribozyme with a disrupted loop-receptor interaction.  305:11-21. 2001
  • Crystal structure and novel recognition motif of rho adp-ribosylating c3 exoenzyme from clostridium botulinum: Structural insights for recognition specificity and catalysis.  305:95-107. 2001
  • Structure-activity relationships in flexible protein domains: Regulation of Rho GTPases by RhoGDI and D4 GDI.  305:121-135. 2001
  • Structure of the PHD zinc finger from human Williams-Beuren syndrome transcription factor.  304:723-729. 2000
  • Structure-activity relationships in a peptidic alpha 7 nicotinic acetylcholine receptor antagonist.  304:911-926. 2000
  • Solution structure and acetyl-lysine binding activity of the GCN5 bromodomain.  304:355-370. 2000
  • Deuterium-proton exchange on the native wild-type transthyretin tetramer identifies the stable core of the individual subunits and indicates mobility at the subunit interface.  303:555-565. 2000
  • Insights into the molecular recognition of the 5 '-gnn-3 ' family of DNA sequences by zinc finger domains.  303:489-502. 2000
  • Structure of a mutant EF-G reveals domain III and possibly the fusidic acid binding site.  303:593-603. 2000
  • Electron microscopic evidence for the assembly of soluble pentameric extracellular domains of the nicotinic acetylcholine receptor.  303:185-196. 2000
  • Solution structure of the TAZ2 (CH3) domain of the transcriptional adaptor protein CBP.  303:243-253. 2000
  • Structure of native and expanded sobemoviruses by electron cryo-microscopy and image reconstruction.  303:197-211. 2000
  • Catalysis of decarboxylation by a preorganized heterogeneous microenvironment: Crystal structures of abzyme 21D8.  302:1213-1225. 2000
  • NMR and molecular dynamics studies of the hydration of a zinc finger-DNA complex.  302:1101-1117. 2000
  • Structures of thermolabile mutants of human glutathione transferase P1-1.  302:295-302. 2000
  • Examination of the transcription factor NtcA-binding motif by in vitro selection of DNA sequences from a random library.  301:783-793. 2000
  • The structural basis for in situ activation of DNA alkylation by duocarmycin sa.  300:1195-1204. 2000
  • Solution structure of the cysteine-rich domain of the Escherichia coli chaperone protein DnaJ.  300:805-818. 2000
  • Structure of a thioredoxin-like 2fe-2s ferredoxin from aquifex aeolicus.  300:587-595. 2000
  • Homodimeric peptides displayed by the major coat protein of filamentous phage.  300:307-320. 2000
  • Alternative conformations of a nucleic acid four-way junction.  300:93-102. 2000
  • Large conformational changes in the maturation of a simple rna virus, nudaurelia capensis omega virus (n omega v).  299:573-584. 2000
  • Ligand-induced stabilization of PPARgamma monitored by NMR spectroscopy: implications for nuclear receptor activation.  298:187-194. 2000
  • Mapping the transition state of the WW domain beta-sheet.  298:283-292. 2000
  • Aminoglycoside binding in the major groove of duplex rna: The thermodynamic and electrostatic forces that govern recognition.  298:95-110. 2000
  • Structure of the CAD domain of caspase-activated DNase and interaction with the CAD domain of its inhibitor.  297:1121-1128. 2000
  • Structure and function of the hairpin ribozyme.  297:269-291. 2000
  • The high resolution crystal structure of green abalone sperm lysin: Implications for species-specific binding of the egg receptor.  296:1225-1234. 2000
  • Conformational flexibility of b-DNA at 0.74 Å resolution: D(ccagtactgg)(2).  296:787-801. 2000
  • Active and inhibited human catalase structures: Ligand and nadph binding and catalytic mechanism.  296:295-309. 2000
  • Cu,Zn superoxide dismutase structure from a microbial pathogen establishes a class with a conserved dimer interface.  296:145-153. 2000
  • NMR solution structure of the inserted domain of human leukocyte function associated antigen-1.  295:1251-1264. 2000
  • DNA-induced alpha-helix capping in conserved linker sequences is a determinant of binding affinity in Cys(2)-His(2) zinc fingers.  295:719-727. 2000
  • Nmr structure of the sterol carrier protein-2: Implications for the biological role.  295:595-603. 2000
  • Structural effects of DNA sequence on T.A recognition by hydroxypyrrole/pyrrole pairs in the minor groove.  295:557-567. 2000
  • The kinetic mechanism of the hairpin ribozyme in vivo: Influence of RNA helix stability on intracellular cleavage kinetics.  295:693-707. 2000
  • Pulling chromatin fibers: Computer simulations of direct physical micromanipulations.  295:29-40. 2000
  • Mutational analysis of the affinity maturation of antibody 48G7.  294:1191-1201. 1999
  • Projection structure of a plant vacuole membrane aquaporin by electron cryo-crystallography.  294:1337-1349. 1999
  • Antibody binding defines a structure for an epitope that participates in the prpc -> prpsc conformational change.  293:855-863. 1999
  • Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm.  293:321-331. 1999
  • Roles for glycosylation of cell surface receptors involved in cellular immune recognition.  293:351-366. 1999
  • Mutational analysis and NMR spectroscopy of quail cysteine and glycine-rich protein CRP2 reveal an intrinsic segmental flexibility of LIM domains.  292:893-908. 1999
  • Conformational changes of the bs2 operator DNA upon complex formation with the antennapedia homeodomain studied by NMR with c-13/n-15-labeled DNA.  292:609-617. 1999
  • Local folding coupled to RNA binding in the yeast ribosomal protein L30.  292:345-359. 1999
  • Sequence homology and structural analysis of the clostridial neurotoxins.  291:1091-1104. 1999
  • Identification of a minimal domain of 5 S ribosomal RNA sufficient for high affinity interactions with the RNA-specific zinc fingers of transcription factor IIIA.  291:549-560. 1999
  • Nmr structure of the sea urchin (strongylocentrotus purpuratus) metallothionein mta.  291:417-428. 1999
  • Structural basis for amide hydrolysis catalyzed by the 43C9 antibody.  291:329-345. 1999
  • Unfolding and refolding of human glyoxalase II and its single-tryptophan mutants.  291:481-490. 1999
  • Benzoic acid derivatives induce recovery of catalytic activity in the partially inactive Met208Lys mutant of human glutathione transferase A1-1.  288:787-800. 1999
  • Nicotinic acetylcholine receptor at 4.6 Å resolution: Transverse tunnels in the channel wall.  288:765-786. 1999
  • Human glutathione transferase a4-4 crystal structures and mutagenesis reveal the basis of high catalytic efficiency with toxic lipid peroxidation products.  288:427-439. 1999
  • Structural analyses of CREB-CBP transcriptional activator-coactivator complexes by NMR spectroscopy: implications for mapping the boundaries of structural domains.  287:859-865. 1999
  • Evolution of differential substrate specificities in Mu class glutathione transferases probed by DNA shuffling.  287:265-276. 1999
  • Motor protein decoration of microtubules grown in high salt conditions reveals the presence of mixed lattices.  287:287-292. 1999
  • Protein mimicry of DNA from crystal structures of the uracil-DNA glycosylase inhibitor protein and its complex with escherichia coli uracil-DNA glycosylase.  287:331-346. 1999
  • Coevolution and subsite decomposition for the design of resistance-evading HIV-1 protease inhibitors.  287:77-92. 1999
  • Minor groove DNA-protein contacts upstream of a tRNA gene detected with a synthetic DNA binding ligand.  286:973-981. 1999
  • The internal equilibrium of the hairpin ribozyme: Temperature, ion and pH effects.  286:1009-1024. 1999
  • Three-dimensional placement of the conserved 530 loop of 16 S rRNA and of its neighboring components in the 30 S subunit.  286:521-540. 1999
  • Effect of H helix destabilizing mutations on the kinetic and equilibrium folding of apomyoglobin.  285:269-282. 1999
  • Imaging RNA and dynamic protein segments with low-resolution virus crystallography: experimental design, data processing and implications of electron density maps.  284:1439-1452. 1998
  • Self-organizing neural networks bridge the biomolecular resolution gap.  284:1247-1254. 1998
  • DNA-induced conformational changes are the basis for cooperative dimerization by the DNA binding domain of the retinoid X receptor.  284:533-539. 1998
  • The 1.25 A resolution refinement of the cholera toxin B-pentamer: evidence of peptide backbone strain at the receptor-binding site.  282:1043-1059. 1998
  • Fast folding mutants of the Tetrahymena group I ribozyme reveal a rugged folding energy landscape.  281:609-620. 1998
  • Protein subunit interactions and structural integrity of amyloidogenic transthyretins: Evidence from electrospray mass spectrometry.  281:553-564. 1998
  • High-resolution solution structure of the retinoid X receptor DNA-binding domain.  281:271-284. 1998
  • Structural basis for the binding of an anti-cytochrome c antibody to its antigen: Crystal structures of FabE8 cytochrome c complex to 1.8 Å resolution and FabE8 to 2.26 Å resolution.  281:301-322. 1998
  • Recommendations for the presentation of NMR structures of proteins and nucleic acids.  280:933-952. 1998
  • A bisubstrate analog induces unexpected conformational changes in phosphoglycerate kinase from trypanosoma brucei.  279:1137-1148. 1998
  • Structure of azotobacter vinelandii 7fe ferredoxin at 1.35 Å resolution and determination of the fe-s bonds with 0.01 Å accuracy.  278:629-639. 1998
  • Structure-activity relationships and thermal stability of human glutathione transferase P1-1 governed by the H-site residue 105.  278:687-698. 1998
  • Calculations on folding of segment B1 of streptococcal protein G.  278:439-456. 1998
  • Sedimentation and electrophoretic migration of DNA knots and catenanes.  278:1-3. 1998
  • Influence of cofactor binding and active site occupancy on the conformation of the macromolecular substrate exosite of factor viia.  277:959-971. 1998
  • The mechanism of an inhibitory antibody on TF-initiated blood coagulation revealed by the crystal structures of human tissue factor, Fab 5G9 and TF.G9 complex.  275:873-894. 1998
  • Protein and Mg(2+)-induced conformational changes in the S15 binding site of 16 S ribosomal RNA.  275:453-464. 1998
  • Analysis of hapten binding and catalytic determinants in a family of catalytic antibodies.  275:95-111. 1998
  • Importance of minor groove binding zinc fingers within the transcription factor IIIA-DNA complex.  274:439-445. 1997
  • A conformational transition at the n terminus of the prion protein features in formation of the scrapie isoform.  273:614-622. 1997
  • Partially folded states of the capsid protein of cowpea severe mosaic virus in the disassembly pathway.  273:456-466. 1997
  • Solution structure of the first three zinc fingers of TFIIIA bound to the cognate DNA sequence: Determinants of affinity and sequence specificity.  273:183-206. 1997
  • Torsion angle dynamics for NMR structure calculation with the new program dyana.  273:283-298. 1997
  • Transcriptional analysis of the caulobacter 4.5 s rna ffs gene and the physiological basis of an ffs mutant with a ts phenotype.  272:665-676. 1997
  • Two conformations of RNA polymerase II revealed by electron crystallography.  272:536-540. 1997
  • Projection structure of VP6, the rotavirus inner capsid protein, and comparison with bluetongue VP7.  272:362-368. 1997
  • High resolution solution structure of a DNA duplex alkylated by the antitumor agent duocarmycin SA.  272:237-252. 1997
  • Molecular recognition in signal transduction: The interaction surfaces of the spo0f response regulator with its cognate phosphorelay proteins revealed by alanine scanning mutagenesis.  272:200-212. 1997
  • The NMR solution conformation of unligated human cyclophilin A.  272:64-81. 1997
  • Multiple cycles of global unfolding of groel-bound cyclophilin a evidenced by NMR.  271:803-818. 1997
  • Fine tuning a molecular motor: The location of alternative domains in the drosophila myosin head.  271:1-6. 1997
  • Thermodynamics of a reverse turn motif. Solvent effects and side-chain packing.  270:305-317. 1997
  • Quasi-equivalent viruses: A paradigm for protein assemblies.  269:665-675. 1997
  • Conformational changes due to calcium-induced calmodulin dissociation in brush border myosin i-decorated f-actin revealed by cryoelectron microscopy and image analysis.  269:548-557. 1997
  • Species-specific tRNA recognition in relation to tRNA synthetase contact residues.  269:1-9. 1997
  • Crystal structures of the free and liganded form of an esterolytic catalytic antibody.  268:390-400. 1997
  • Flexible linker in the RNA polymerase alpha subunit facilitates the independent motion of the C-terminal activator contact domain.  267:953-962. 1997
  • Mapping the protein surface of human immunodeficiency virus type 1 gp120 using human monoclonal antibodies from phage display libraries.  267:684-695. 1997
  • Solution structure of the HIV-2 TAR-argininamide complex.  267:624-639. 1997
  • The NMR solution structure of the non-classical homeodomain from the rat liver lfb1/hnf1 transcription factor.  267:673-683. 1997
  • Opposite effect of counterions on the persistence length of nicked and non-nicked DNA.  266:711-721. 1997
  • Nmr solution structure of the pathogenesis-related protein p14a.  266:576-593. 1997
  • Three-dimensional structure of brush border myosin-i at similar to 20 Å resolution by electron microscopy and image analysis.  266:331-342. 1997
  • Structure-based design of a constrained peptide mimic of the HIV-1 V3 loop neutralization site.  266:31-39. 1997
  • Motor domains of kinesin and ncd interact with microtubule protofilaments with the same binding geometry.  265:553-564. 1997
  • Nuclear protein import is decreased by engineered mutants of nuclear transport factor 2 (ntf2) that do not bind gdp-ran.  272:716-730. 1997
  • Structural role of a buried salt bridge in the 434 repressor DNA-binding domain.  264:1002-1012. 1996
  • A novel promoter motif for caulobacter cell cycle-controlled DNA replication genes.  264:412-425. 1996
  • NMR solution structure of Cu(I) rusticyanin from Thiobacillus ferrooxidans: structural basis for the extreme acid stability and redox potential.  263:752-767. 1996
  • Is apomyoglobin a molten globule? Structural characterization by NMR.  263:531-538. 1996
  • Polarity of 2-d and 3-d maps of tubulin sheets and motor-decorated sheets.  263:114-119. 1996
  • Protein and DNA requirements for the transcription factor IIIA-induced distortion of the 5 S rRNA gene promoter.  262:600-614. 1996
  • Specialization of the DNA-cleaving activity of a group I ribozyme through in vitro evolution.  262:31-42. 1996
  • Surface display of proteins on bacteriophage lambda heads.  262:21-30. 1996
  • A mutation in the human cyclin-dependent kinase interacting protein, ckshs2, interferes with cyclin-dependent kinase binding and biological function, but preserves protein structure and assembly.  261:646-657. 1996
  • The 2.8 Å structure of a T=4 animal virus and its implications for membrane translocation of RNA.  261:1-10. 1996
  • Three-dimensional structure of ncd-decorated microtubules obtained by a back-projection method.  260:743-755. 1996
  • Nmr structure of the j-domain and the gly/phe-rich region of the escherichia coli dnaj chaperone.  260:236-250. 1996
  • Isolation, characterization and evolution of nine pufferfish (Fugu rubripes) actin genes.  259:655-665. 1996
  • Projection structure of the nicotinic acetylcholine receptor: Distinct conformations of the alpha subunits.  257:586-596. 1996
  • Crystal structures of apolipoprotein(a) kringle iv37 free and complexed with 6-aminohexanoic acid and with p-aminomethylbenzoic acid: Existence of novel and expected binding modes.  256:751-761. 1996
  • The bacillus subtilis response regulator spooa stimulates transcription of the spoiig operon through modification of rna polymerase promoter complexes.  256:436-448. 1996
  • MPD and DNA bending in crystals and in solution.  256:108-125. 1996
  • Interaction of the Bacillus stearothermophilus ribosomal protein S15 with 16 S rRNA: I. Defining the minimal RNA site.  261:536-549. 1996
  • Interaction of the Bacillus stearothermophilus ribosomal protein S15 with 16 S rRNA: II. Specificity determinants of RNA-protein recognition.  261:550-567. 1996
  • Determination of DNA persistence length by cryoelectron microscopy - separation of the static and dynamic contributions to the apparent persistence length of DNA.  254:579-591. 1995
  • Cdr walking mutagenesis for the affinity maturation of a potent human anti-hiv-1 antibody into the picomolar range.  254:392-403. 1995
  • The modular character of a DNA junction-resolving enzyme - a zinc-binding motif in bacteriophage-T4 endonuclease-VII.  252:596-610. 1995
  • Prediction of quaternary structure of coiled coils. Application to mutants of the GCN4 leucine zipper.  251:448-467. 1995
  • Use of flow-cytometry to identify a caulobacter 4.5 s rna temperature-sensitive mutant defective in the cell-cycle.  251:346-365. 1995
  • Repression of vertebrate RNA-polymerase-III transcription by DNA-binding proteins located upstream from the transcription start site.  250:315-326. 1995
  • Glutathione transferases with novel active sites isolated by phage display from a library of random mutants.  250:115-122. 1995
  • Crystal-structure of the human cell-cycle protein ckshs1 - single-domain fold with similarity to kinase n-lobe domain.  249:835-842. 1995
  • Towards structure-based drug design - crystal-structure of a multisubstrate adduct complex of glycinamide ribonucleotide transformylase at 1.96 Å resolution.  249:153-175. 1995
  • Interaction of the RNA-binding fingers of Xenopus transcription factor IIIA with specific regions of 5-S ribosomal-RNA.  248:44-57. 1995
  • Functional significance of arginine 15 in the active site of human class alpha glutathione transferase A1-1..  247:765-773. 1995
  • Internal mobility of the basic pancreatic trypsin-inhibitor in solution - a comparison of NMR spin relaxation measurements and molecular-dynamics simulations.  246:356-365. 1995
  • Binding of the junction-resolving enzyme bacteriophage-T7 endonuclease-I to DNA - separation of binding and catalysis by mutation.  246:95-107. 1995
  • Crystal-structures of a schistosomal drug and vaccine target - glutathione-s-transferase from schistosoma-japonica and its complex with the leading antischistosomal drug praziquantel.  246:21-27. 1995
  • Crystallization and preliminary crystallographic data for rab guanine-nucleotide dissociation inhibitor (rabgdi) from bovine brain.  244:469-473. 1994
  • Nuclear magnetic resonance (15)N and (1)H resonance assignments and global fold of rusticyanin. Insights into the ligation and acid stability of the blue copper site.  244:370-384. 1994
  • Solution structure of carbonmonoxy myoglobin determined from nuclear-magnetic-resonance distance and chemical-shift constraints.  244:183-197. 1994
  • Relative contributions of the zinc fingers of transcription factor IIIA to the energetics of DNA-binding.  244:23-35. 1994
  • Stabilization of a type VI turn in a family of linear peptides in water solution.  243:736-753. 1994
  • Three-dimensional structure of a type VI turn in a linear peptide in water solution. Evidence for stacking of aromatic rings as a major stabilizing factor.  243:754-766. 1994
  • Structural-analysis of antibody specificity - detailed comparison of 5 fab'-steroid complexes.  241:663-690. 1994
  • Crystal-structure of a peptide complex of antiinfluenza peptide antibody-Fab-26/9 - comparison of 2 different antibodies bound to the same peptide antigen.  241:534-556. 1994
  • Crystallization and preliminary crystallographic analysis of peptide-n-4-(n-acetyl-beta-d-glucosaminyl)asparagine amidase pngase-f.  241:622-623. 1994
  • Diffraction quality crystals of protein-x from azotobacter-vinelandii.  241:620-621. 1994
  • Simultaneous refinement of the structure of bpti against NMR data measured in solution and x-ray-diffraction data measured in single-crystals.  241:588-599. 1994
  • The crystal-structure of C-C-A-T-T-A-A-T-G-G - implications for bending of B-DNA at T-A steps.  239:79-96. 1994
  • Structure of phaseolin at 2.2 Å resolution - implications for a common vicilin/legumin structure and the genetic-engineering of seed storage proteins.  238:748-776. 1994
  • Nuclear-magnetic-resonance solution structure of the fushi-tarazu homeodomain from drosophila and comparison with the antennapedia homeodomain.  238:333-345. 1994
  • Structure of four-way DNA junctions containing a nick in one strand.  238:62-74. 1994
  • Crystal-structures of aconitase with trans-aconitate and nitrocitrate bound.  237:437-451. 1994
  • Prediction of the folding pathways and structure of the GCN4 leucine zipper..  237:361-367. 1994
  • The nuclear-magnetic-resonance solution structure of the mixed disulfide between escherichia-coli glutaredoxin(c14s) and glutathione.  235:1585-1597. 1994
  • Catalytic antibody model and mutagenesis implicate arginine in transition-state stabilization.  235:1098-1116. 1994
  • Determination of the nuclear-magnetic-resonance structure of the DNA-binding domain of the p22 c2 repressor (1 to 76) in solution and comparison with the DNA-binding domain of the 434 repressor.  235:1003-1020. 1994
  • The refined three-dimensional structure of an insect virus at 2.8-Å resolution.  235:565-586. 1994
  • Detailed analysis of the free and bound conformations of an antibody - x-ray structures of fab 17/9 and 3 different fab-peptide complexes.  234:1098-1118. 1993
  • Determination of the nuclear-magnetic-resonance solution structure of an antennapedia homeodomain-DNA complex.  234:1084-1094. 1993
  • Model studies relating nuclear-magnetic-resonance data with the 3-dimensional structure of protein-DNA complexes.  234:1094-1097. 1993
  • Nuclear-magnetic-resonance spectroscopy of a DNA complex with the uniformly c-13-labeled antennapedia homeodomain and structure determination of the DNA-bound homeodomain.  234:1070-1083. 1993
  • Nuclear-magnetic-resonance solution structure of dendrotoxin-k from the venom of dendroaspis-polylepis-polylepis.  234:735-750. 1993
  • Structure determination and refinement of human alpha class glutathione transferase A1-1, and a comparison with the Mu and Pi class enzymes.  232:192-212. 1993
  • Hydration of proteins - a comparison of experimental residence times of water-molecules solvating the bovine pancreatic trypsin-inhibitor with theoretical-model calculations.  231:1040-1048. 1993
  • Nuclear-magnetic-resonance solution structure of the pheromone er-10 from the ciliated protozoan euplotes-raikovi.  231:800-816. 1993
  • Three-dimensional structure of an anti-steroid Fab' and progesterone-Fab' complex.  231:103-118. 1993
  • Molecular profile of an antibody-response to hiv-1 as probed by combinatorial libraries.  230:812-823. 1993
  • Nicotinic acetylcholine-receptor at 9 Å resolution.  229:1101-1124. 1993
  • Purification, crystallization and space group determination of DNA-repair enzyme exonuclease-iii from escherichia-coli.  229:239-242. 1993
  • Impact of protein protein contacts on the conformation of thrombin-bound hirudin studied by comparison with the nuclear-magnetic-resonance solution structure of hirudin(1-51).  228:1206-1211. 1992
  • Nuclear-magnetic-resonance solution structure of hirudin(1-51) and comparison with corresponding 3-dimensional structures determined using the complete 65-residue hirudin polypeptide-chain.  228:1193-1205. 1992
  • Crystallization of murine major histocompatibility complex class-i h-2kb with single peptides.  228:975-982. 1992
  • The interdependence of protein surface-topography and bound water-molecules revealed by surface accessibility and fractal density measures.  228:13-22. 1992
  • Nuclear-magnetic-resonance solution structure of the alpha-neurotoxin from the black mamba (dendroaspis-polylepis-polylepis).  227:1118-1135. 1992
  • Determination of a high-quality nuclear-magnetic-resonance solution structure of the bovine pancreatic trypsin-inhibitor and comparison with 3 crystal-structures.  227:757-775. 1992
  • Crystal-structure of glycinamide ribonucleotide transformylase from escherichia-coli at 3.0 Å resolution - a target enzyme for chemotherapy.  227:283-292. 1992
  • Crystallization and crystallographic characterization of the iron sulfur-containing DNA-repair enzyme endonuclease-iii from escherichia-coli.  227:347-351. 1992
  • Comparison of the solution conformations of human zn7 -metallothionein-2 and cd7 -metallothionein-2 using nuclear-magnetic-resonance spectroscopy.  225:433-443. 1992
  • Membrane topology and quaternary structure of cardiac gap junction ion channels.  223:929-948. 1992
  • Specific interaction of the 1st-3 zinc fingers of TFIIIA with the internal control region of the Xenopus 5S RNA gene.  223:857-871. 1992
  • Determination of the nuclear-magnetic-resonance solution structure of the DNA-binding domain (residues 1 to 69) of the 434 repressor and comparison with the x-ray crystal-structure.  223:743-767. 1992
  • Folding of peptide fragments comprising the complete sequence of proteins. Models for initiation of protein folding. I. Myohemerythrin.  226:795-817. 1992
  • Folding of peptide fragments comprising the complete sequence of proteins. Models for initiation of protein folding. II. Plastocyanin.  226:819-835. 1992
  • Crystallization and preliminary-x-ray analysis of botulinum neurotoxin type-a.  222:877-880. 1991
  • Characterization of the memory gene dunce of Drosophila melanogaster.  222:553-565. 1991
  • Refined crystal-structure of cd, zn metallothionein at 2.0 a resolution.  221:1269-1293. 1991
  • Sequence-specific h-1-NMR assignments and determination of the 3-dimensional structure of reduced escherichia-coli glutaredoxin.  221:1311-1324. 1991
  • Biochemical implications from the variable gene-sequences of an anti-cytochrome-c antibody and crystallographic characterization of its antigen-binding fragment in free and antigen-complexed forms.  221:455-462. 1991
  • High-resolution solution structure of reduced french bean plastocyanin and comparison with the crystal-structure of poplar plastocyanin.  221:533-555. 1991
  • Effects of base mismatches on the structure of the four-way DNA junction.  221:147-161. 1991
  • Efficient computation of 3-dimensional protein structures in solution from nuclear-magnetic-resonance data using the program diana and the supporting programs caliba, habas and glomsa.  217:517-530. 1991
  • Structure determination of the antp(c39- s) homeodomain from nuclear-magnetic-resonance data in solution using a novel strategy for the structure calculation with the programs diana, caliba, habas and glomsa.  217:531-540. 1991
  • Structure, function and properties of antibody binding sites.  217:133-151. 1991
  • Trigonal crystals of porcine mitochondrial aspartate-aminotransferase.  215:341-344. 1990
  • Amide proton-exchange in human metallothionein-2 measured by nuclear-magnetic-resonance spectroscopy.  214:781-786. 1990
  • Establishment of denovo DNA methylation patterns - transcription factor binding and deoxycytidine methylation at cpg and non-cpg sequences in an integrated adenovirus promoter.  214:673-683. 1990
  • Three-dimensional structure of human [113Cd7]metallothionein-2 in solution determined by nuclear magnetic resonance spectroscopy.  214:765-779. 1990
  • Structural homology among 4 nodaviruses as deduced by sequencing and x-ray crystallography.  214:423-435. 1990
  • Determination of the 3-dimensional structure of the antennapedia homeodomain from drosophila in solution by h-1 nuclear-magnetic-resonance spectroscopy.  214:183-197. 1990
  • Crystallographic characterization of a Cu,Zn superoxide-dismutase from Photobacterium-leiognathi.  212:449-451. 1990
  • Crystallization of GST2, a human class alpha glutathione transferase.  208:369-370. 1989
  • Comparison of the high-resolution structures of the alpha-amylase inhibitor tendamistat determined by nuclear magnetic-resonance in solution and by x-ray-diffraction in single-crystals.  206:677-687. 1989
  • On the assembly of sickle hemoglobin fascicles.  206:637-649. 1989
  • Solution of the phase problem in the x-ray-diffraction method for proteins with the nuclear magnetic-resonance solution structure as initial model - patterson search and refinement for the alpha-amylase inhibitor tendamistat.  206:669-676. 1989
  • Ermc leader peptide - amino-acid sequence critical for induction by translational attenuation.  206:69-79. 1989
  • Refinement of the fe-7 ferredoxin from azotobacter-vinelandii at 1.9-a resolution.  205:545-555. 1989
  • Determination of the complete 3-dimensional structure of the alpha-amylase inhibitor tendamistat in aqueous-solution by nuclear magnetic-resonance and distance geometry.  204:675-724. 1988
  • Statistical positioning of nucleosomes by specific protein-binding to an upstream activating sequence in yeast.  204:109-127. 1988
  • Crystallization of a small fragment of an aminoacyl tRNA synthetase.  203:521-522. 1988
  • Conformation of cd7 -metallothionein-2 from rat-liver in aqueous-solution determined by nuclear magnetic-resonance spectroscopy.  203:251-268. 1988
  • Complete assignment of the h-1 nuclear magnetic-resonance spectrum of french bean plastocyanin - application of an integrated approach to spin system-identification in proteins.  202:603-622. 1988
  • Complete assignment of the h-1 nuclear magnetic-resonance spectrum of french bean plastocyanin - sequential resonance assignments, secondary structure and global fold.  202:623-636. 1988
  • Reactivation of the methylation-inactivated late e2a promoter of adenovirus type-2 by e1a (13-s) functions.  202:255-270. 1988
  • Three-dimensional structure of rabbit liver [Cd7]metallothionein-2a in aqueous solution determined by nuclear magnetic resonance.  201:637-657. 1988
  • Evidence for a unique first position codon-anticodon mismatch in vivo.  201:451-454. 1988
  • Structural-analysis of polymers of sickle-cell hemoglobin .1. Sickle hemoglobin fibers.  199:315-331. 1988
  • Structural-analysis of polymers of sickle-cell hemoglobin .2. Sickle hemoglobin macrofibers.  199:333-348. 1988
  • Folding of immunogenic peptide fragments of proteins in water solution. I. Sequence requirements for the formation of a reverse turn.  201:161-200. 1988
  • Folding of immunogenic peptide fragments of proteins in water solution. II. The nascent helix.  201:201-217. 1988
  • Metal coordination in rat-liver metallothionein-2 prepared with or without reconstitution of the metal-clusters, and comparison with rabbit liver metallothionein-2.  196:711-719. 1987
  • Protein structures in solution by nuclear-magnetic-resonance and distance geometry - the polypeptide fold of the basic pancreatic trypsin-inhibitor determined using 2 different algorithms, disgeo and disman.  196:611-639. 1987
  • Assignment of resonances in the h-1 nuclear-magnetic-resonance spectrum of the carbon-monoxide complex of human-hemoglobin alpha-chains.  194:329-339. 1987
  • Assignment of resonances in the h-1 nuclear-magnetic-resonance spectrum of the carbon-monoxide complex of sperm whale myoglobin by phase-sensitive two-dimensional techniques.  194:313-327. 1987
  • Complete sequence-specific h-1 nuclear-magnetic-resonance assignments for the alpha-amylase polypeptide inhibitor tendamistat from streptomyces-tendae.  192:869-890. 1986
  • H-1-nuclear magnetic-resonance assignments for d-(gcattaatgc)2 using experimental refinements of established procedures.  190:439-453. 1986
  • Nonenzymatic template-directed synthesis on RNA random copolymers - Poly(C, G) templates.  188:433-441. 1986
  • An evaluation of the combined use of nuclear magnetic-resonance and distance geometry for the determination of protein conformations in solution.  182:281-294. 1985
  • Binding of an antitumor drug to DNA netropsin and C-G-C-G-A-A-T-T-BrC-G-C-G.  183:553-563. 1985
  • Crystal-structure of azotobacter cytochrome-c5 at 2.5-a resolution.  184:279-295. 1985
  • Messenger-rna from staphylococcus-aureus that specifies "macrolide-lincosamide-streptogramin resistance - demonstration of its conformations and of the leader peptide it encodes.  185:769-780. 1985
  • Solution conformation of proteinase inhibitor-iia from bull seminal plasma by h-1 nuclear magnetic-resonance and distance geometry.  182:295-315. 1985
  • Structural relationship of human interferon-alpha genes and pseudogenes.  185:227-260. 1985
  • Calibration of the angular-dependence of the amide proton-c-alpha proton coupling-constants, 3jhn-alpha, in a globular protein - use of 3jhn-alpha for identification of helical secondary structure.  180:741-751. 1984
  • Neutron-scattering studies of subcomponent clq of 1st component cl of human-complement and its association with subunit clr2cls2 within cl.  179:547-557. 1984
  • Non-enzymatic template-directed synthesis on RNA random copolymers - Poly(C,U) templates.  176:279-306. 1984
  • Polypeptide secondary structure determination by nuclear magnetic-resonance observation of short proton proton distances.  180:715-740. 1984
  • Secondary structure in the solution conformation of the proteinase inhibitor-iia from bull seminal plasma by nuclear magnetic-resonance.  173:341-359. 1984
  • Template-directed synthesis on the pentanucleotide CpCpGpCpC.  178:669-676. 1984
  • Assignment of the h-1 nuclear magnetic-resonance spectrum of the proteinase inhibitor-iia from bull seminal plasma by two-dimensional nuclear magnetic-resonance at 500 mhz.  166:641-667. 1983
  • Assignment of the h-1 nuclear magnetic-resonance spectrum of the trypsin-inhibitor homologue-k from dendroaspis-polylepis-polylepis - 2 dimensional nuclear magnetic-resonance at 360 and 500 mhz.  163:623-646. 1983
  • Characterization of the proteinase inhibitor-iia from bull seminal plasma by h-1 nuclear magnetic-resonance - stability, amide proton-exchange and mobility of aromatic residues.  166:631-640. 1983
  • Conformation of glucagon in a lipid water interphase by h-1 nuclear magnetic-resonance.  169:921-948. 1983
  • Preliminary structural comparison of the proteinase isoinhibitors-iia and isoinhibitor-iib from bull seminal plasma based on individual assignments of the h-1 nuclear magnetic-resonance spectra by two-dimensional nuclear magnetic-resonance at 500 mhz.  166:669-676. 1983
  • Pseudo-structures for the 20 common amino-acids for use in studies of protein conformations by measurements of intramolecular proton proton distance constraints with nuclear magnetic-resonance.  169:949-961. 1983
  • Structure of a t=1 aggregate of alfalfa mosaic-virus coat protein seen at 4.5-a resolution.  167:873-890. 1983
  • Structure of tomato busy stunt virus. IV. The virus particle at 2.9 A resolution.  171:61-93. 1983
  • Amide proton-exchange and surface conformation of the basic pancreatic trypsin-inhibitor in solution - studies with two-dimensional nuclear magnetic-resonance.  160:343-361. 1982
  • Assignment of the h-1 nuclear magnetic-resonance spectrum of the trypsin inhibitor-e from dendroaspis-polylepis-polylepis two-dimensional nuclear magnetic-resonance at 500 mhz.  159:323-351. 1982
  • Determination and analysis of the 2A structure of copper, zinc superoxide-dismutase.  160:181-217. 1982
  • Distribution of rna and protein in crystalline eukaryotic ribosomes.  156:431-448. 1982
  • Iron-sulfur clusters and protein-structure of azotobacter ferredoxin at 2.0 a resolution.  158:73-109. 1982
  • Sequential resonance assignments as a basis for determination of spatial protein structures by high-resolution proton nuclear magnetic-resonance.  155:311-319. 1982
  • Sequential resonance assignments in protein h-1 nuclear magnetic-resonance spectra - basic pancreatic trypsin-inhibitor.  155:347-366. 1982
  • Sequential resonance assignments in protein h-1 nuclear magnetic-resonance spectra - computation of sterically allowed proton proton distances and statistical-analysis of proton proton distances in single-crystal protein conformations.  155:321-346. 1982
  • Sequential resonance assignments in protein h-1 nuclear magnetic-resonance spectra - glucagon bound to perdeuterated dodecylphosphocholine micelles.  155:367-388. 1982
  • Interactions of Qβ replicase with Qβ RNA.  153:631-660. 1981
  • Conformational transition from trypsinogen to trypsin - h-1 nuclear magnetic-resonance at 360 mhz and ring current calculations.  138:43-64. 1980
  • Neutron-diffraction analysis of the structure of rod photoreceptor-membranes in intact retinas.  137:315-348. 1980
  • Structure of lobster apo-d-glyceraldehyde-3-phosphate dehydrogenase at 3.0 a resolution.  138:859-872. 1980
  • Attachment of ribosome crystals to intracellular membranes.  132:69-84. 1979
  • Correlation between the amide proton-exchange rates and the denaturation temperatures in globular-proteins related to the basic pancreatic trypsin-inhibitor.  130:31-37. 1979
  • Escherichia coli ribosomes bind to non-initiator sites of Qβ RNA in the absence of formylmethionyl transfer RNA.  128:481-500. 1979
  • Kinetics of the exchange of individual amide protons in the basic pancreatic trypsin-inhibitor.  130:19-30. 1979
  • Nuclear magnetic-resonance of labile protons in the basic pancreatic trypsin-inhibitor.  130:1-18. 1979
  • Preparation and characterization of form-v DNA, the duplex DNA resulting from association of complementary, circular single-stranded-DNA.  131:21-40. 1979
  • Structural interpretation of the amide proton-exchange in the basic pancreatic trypsin-inhibitor and related proteins.  134:75-94. 1979
  • Two forms of isolated gap junctions.  135:451-464. 1979
  • Site-directed mutagenesis in DNA: generation of point mutations in cloned β globin complementary DNA at the positions corresponding to amino acids 121 to 123.  124:343-358. 1978
  • Site-directed mutations in initiator region of bacteriophage Qβ coat cistron and their effect on ribosome binding.  118:533-565. 1978
  • A guanosine to adenosine transition in the 3' terminal extracistronic region of bacteriophage Qβ RNA leading to loss of infectivity.  112:235-252. 1977
  • Isolation, characterization and structural implications of a nuclease-digested complex of aminoacyl transfer RNA and Escherichia coli elongation factor Tu.  114:451-458. 1977
  • Nano-variant rnas - nucleotide-sequence and interaction with bacteriophage qbeta replicase.  117:877-907. 1977
  • Packing of ribosomes in crystals from lizard lacerta-sicula.  114:491-506. 1977
  • Rapid accumulation and disappearance of plasma-membrane proteins during development of wild-type and mutant strains of dictyostelium-discoideum.  116:469-488. 1977
  • Developmentally regulated proteins of plasma-membrane of dictyostelium-discoideum - carbohydrate-binding protein.  100:157-178. 1976
  • Physical mapping of qbeta replicase binding-sites on qbeta rna.  101:367-377. 1976
  • Purification of globin messenger-rna from dimethylsulfoxide-induced friend cells and detection of a putative globin messenger-rna precursor.  106:1061-1075. 1976
  • Studies of histidine residues of triose phosphate isomerase by proton magnetic-resonance and x-ray crystallography.  100:319-343. 1976
  • Studies on the mechanism of enzymatic DNA elongation by Escherichia coli DNA polymerase II.  103:61-76. 1976
  • Beef liver catalase structure - interpretation of electron micrographs.  98:235-242. 1975
  • Interaction of polyamines with fragments and whole molecules of yeast phenylalanine-specific transfer RNA.  93:323-329. 1975
  • Molecular structure determination by electron microscopy of unstained crystalline specimens.  94:425-440. 1975
  • A new approach to the isolation of rna-DNA hybrids and its application to the quantitative determination of labeled tumor virus rna.  86:373-396. 1974
  • Electron microscopy of the stacked disk aggregate of tobacco mosaic virus protein. Ii. The influence of electron irradiation of the stain distribution.  87:657-670. 1974
  • Electron microscopy of the stacked disk aggregate of tobacco mosaic-virus protein: 1. Three-dimensional image reconstruction.  87:641-650. 1974
  • Interaction of manganese with fragments, complementary fragment recombinations, and whole molecules of yeast phenylalanine specific transfer RNA.  86:601-620. 1974
  • Photo-induced joining of a transfer RNA with its cognate aminoacyl-transfer RNA synthetase.  84:503-513. 1974
  • Relaxation spectra of the iron spin transition in methemoglobin.  89:505-510. 1974
  • Site-directed mutagenesis: generation of an extracistronic mutation in bacteriophage Qβ RNA.  89:255-272. 1974
  • Appearance of virus-specific DNA in mammalian cells following transformation by rous sarcoma virus.  74:613-626. 1973
  • Isolation and characterization of plasma membrane associated immunoglobulin from cultured human diploid lymphocytes.  76:485-502. 1973
  • Physical properties of cytoplasmic membrane-associated DNA.  78:43-56. 1973
  • Resynchronization of rna synthesis by coliphage qbeta replicase at an internal site of the rna template.  76:271-284. 1973
  • An immunological study of the fates of nuclear and nucleolar macromolecules during the cell cycle.  68:107-114. 1972
  • Structural investigations of modified hemoglobins by nuclear magnetic resonance spectroscopy.  63:477-482. 1972
  • Nuclear magnetic resonance determination of ligand-induced conformational changes in myoglobin.  53:143-157. 1970
  • Proton magnetic resonance studies of cyanoferrihemoglobins from different species.  49:197-202. 1970
  • Conformational energies and configurational statistics of copolypeptides containing L-proline.  34:105-120. 1968
  • Isolation and characterization of a hemagglutinin from limulus polyphemus.  32:453-465. 1968
  • Peptide maps of rabbit γG-immunoglobulin heavy chains controlled by allelic genes.  16:328-333. 1966
  • Peptide differences of rabbit γG-immunoglobulin light chains controlled by allelic genes.  11:713-721. 1965
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Identity

International Standard Serial Number (ISSN)

  • 0022-2836

Electronic International Standard Serial Number (EISSN)

  • 1089-8638

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