recent publications
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academic article
- Boyman, O., Krieg, C., Letourneau, S., Webster, K., Surh, C. D., Sprent, J. Selectively expanding subsets of t cells in mice by injection of interleukin-2/antibody complexes: Implications for transplantation tolerance Transplantation Proceedings 2012 44:1032-1034 DOI:10.1016/j.transproceed.2012.01.093 PMID:22564618
- Letourneau, S., van Leeuwen, E. M. M., Krieg, C., Martin, C., Pantaleo, G., Sprent, J., Surh, C. D., Boyman, O. IL-2/anti-IL-2 antibody complexes show strong biological activity by avoiding interaction with IL-2 receptor α subunit CD25 Proceedings of the National Academy of Sciences of the United States of America 2010 107:2171-2176 DOI:10.1073/pnas.0909384107 PMID:20133862 PMCID:PMC2836659
- Webster, K. E., Walters, S., Kohler, R. E., Mrkvan, T., Boyman, O., Surh, C. D., Grey, S. T., Sprent, J. In vivo expansion of t reg cells with il-2-mab complexes: Induction of resistance to eae and long-term acceptance of islet allografts without immunosuppression Journal of Experimental Medicine 2009 206:751-760 DOI:10.1084/jem.20082824 PMID:19332874 PMCID:PMC2715127
- Boyman, O., Ramsey, C., Kim, D. M., Sprent, J., Surh, C. D. Il-7/anti-il-7 mab complexes restore t cell development and induce homeostatic t cell expansion without lymphopenia Journal of Immunology 2008 180:7265-7275 PMID:18490726
- Sprent, J., Cho, J. H., Boyman, O., Surh, C. D. T cell homeostasis Immunology and Cell Biology 2008 86:312-319 DOI:10.1038/icb.2008.12 PMID:18362947
- Cho, J. H., Boyman, O., Kim, H. O., Hahm, B., Rubinstein, M. P., Ramsey, C., Kim, D. M., Surh, C. D., Sprent, J. An intense form of homeostatic proliferation of naive cd8(+) cells driven by il-2 Journal of Experimental Medicine 2007 204:1787-1801 DOI:10.1084/jem.20070740 PMID:17664294 PMCID:PMC2118670
- Boyman, O., Purton, J. F., Surh, C. D., Sprent, J. Cytokines and t-cell homeostasis Current Opinion in Immunology 2007 19:320-326 DOI:10.1016/j.coi.2007.04.015 PMID:17433869
- Boyman, O., Surh, C. D., Sprent, J. Potential use of il-2/anti-il-2 antibody immune complexes for the treatment of cancer and autoimmune disease Expert Opinion on Biological Therapy 2006 6:1323-1331 DOI:10.1517/14712598.6.12.1323 PMID:17223740
- Boyman, O., Cho, J. H., Tan, J. T., Surh, C. D., Sprent, J. A major histocompatibility complex class I-dependent subset of memory phenotype CD8(+) cells Journal of Experimental Medicine 2006 203:1817-1825 DOI:10.1084/jem.20052495 PMID:16818671 PMCID:PMC2118360
- Rubinstein, M. P., Kovar, M., Purton, J. F., Cho, J. H., Boyman, O., Surh, C. D., Sprent, J. Converting IL-15 to a superagonist by binding to soluble IL-15R alpha Proceedings of the National Academy of Sciences of the United States of America 2006 103:9166-9171 DOI:10.1073/pnas.0600240103 PMID:16757567 PMCID:PMC1482584
- Surh, C. D., Boyman, O., Purton, J. F., Sprent, J. Homeostasis of memory T cells Immunological Reviews 2006 211:154-163 DOI:10.1111/j.0105-2896.2006.00401.x PMID:16824125
- Boyman, O., Kovar, M., Rubinstein, M. P., Surh, C. D., Sprent, J. Selective stimulation of t cell subsets with antibody-cytokine immune complexes Science 2006 311:1924-1927 DOI:10.1126/science.1122927 PMID:16484453