recent publications

• academic article

  • De Guzman, R. N., Goto, N. K., Dyson, H. J., Wright, P. E. Structural basis for cooperative transcription factor binding to the cbp coactivator Journal of Molecular Biology  2006 355:1005-1013  DOI:10.1016/j.jmb.2005.09.059  PMID:16253272
  • De Guzman, R. N., Wojciak, J. M., Martinez-Yamout, M. A., Dyson, H. J., Wright, P. E. Cbp/p300 taz1 domain forms a structured scaffold for ligand binding Biochemistry  2005 44:490-497  DOI:10.1021/bi048161t  PMID:15641773
  • De Guzman, R. N., Martinez-Yamout, M. A., Dyson, H. J., Wright, P. E. Interaction of the taz1 domain of the creb-binding protein with the activation domain of cited2 - regulation by competition between intrinsically unstructured ligands for non-identical binding sites Journal of Biological Chemistry  2004 279:3042-3049  DOI:10.1074/jbc.M310348200  PMID:14594809
  • Zor, T., De Guzman, R. N., Dyson, H. J., Wright, P. E. Solution structure of the kix domain of cbp bound to the transactivation domain of c-myb Journal of Molecular Biology  2004 337:521-534  DOI:10.1016/j.jmb.2004.01.038  PMID:15019774
  • Dames, S. A., Martinez-Yamout, M., De Guzman, R. N., Dyson, H. J., Wright, P. E. Structural basis for hif-1 alpha/cbp recognition in the cellular hypoxic response Proceedings of the National Academy of Sciences of the United States of America  2002 99:5271-5276  DOI:10.1073/pnas.082121399  PMID:11959977  PMCID:PMC122759
  • De Guzman, R. N., Liu, H. Y., Martinez-Yamout, M., Dyson, H. J., Wright, P. E. Solution structure of the TAZ2 (CH3) domain of the transcriptional adaptor protein CBP Journal of Molecular Biology  2000 303:243-253  DOI:10.1006/jmbi.2000.4141  PMID:11023789