recent publications
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academic article
- Salzameda, N. T., Eubanks, L. M., Zakhari, J. S., Tsuchikama, K., DeNunzio, N. J., Allen, K. N., Hixon, M. S., Janda, K. D. A cross-over inhibitor of the botulinum neurotoxin light chain B: A natural product implicating an exosite mechanism of action Chemical Communications 2011 47:1713-1715 DOI:10.1039/c0cc04078a PMID:21203627 PMCID:PMC3065946
- Lowery, C. A., Salzameda, N. T., Sawada, D., Kaufmann, G. F., Janda, K. D. Medicinal chemistry as a conduit for the modulation of quorum sensing Journal of Medicinal Chemistry 2010 53:7467-7489 DOI:10.1021/jm901742c PMID:20669927 PMCID:PMC2974035
- Eubanks, L. M., Silhar, P., Salzameda, N. T., Zakhari, J. S., Xiaochuan, F., Barbieri, J. T., Shoemaker, C. B., Hixon, M. S., Janda, K. D. Identification of a natural product antagonist against the botulinum neurotoxin light chain protease ACS Medicinal Chemistry Letters 2010 1:268-272 DOI:10.1021/ml100074s PMID:20959871 PMCID:PMC2955888
- Silhar, P., Capkova, K., Salzameda, N. T., Barbieri, J. T., Hixon, M. S., Janda, K. D. Botulinum neurotoxin a protease: Discovery of natural product exosite inhibitors Journal of the American Chemical Society 2010 132:2868-2869 DOI:10.1021/ja910761y PMID:20158239 PMCID:PMC2832098
- Salzameda, N. T., Barbieri, J. T., Janda, K. D. Synthetic substrate for application in both high and low throughput assays for botulinum neurotoxin B protease inhibitors Bioorganic & Medicinal Chemistry Letters 2009 19:5848-5850 DOI:10.1016/j.bmcl.2009.08.079 PMID:19747823 PMCID:PMC2753755
- Capkova, K., Salzameda, N. T., Janda, K. D. Investigations into small molecule non-peptidic inhibitors of the botulinum neurotoxins Toxicon 2009 54:575-582 DOI:10.1016/j.toxicon.2009.03.016 PMID:19327377 PMCID:PMC2730986