recent publications

• academic article

  • Salzameda, N. T., Eubanks, L. M., Zakhari, J. S., Tsuchikama, K., DeNunzio, N. J., Allen, K. N., Hixon, M. S., Janda, K. D. A cross-over inhibitor of the botulinum neurotoxin light chain B: A natural product implicating an exosite mechanism of action Chemical Communications  2011 47:1713-1715  DOI:10.1039/c0cc04078a  PMID:21203627  PMCID:PMC3065946
  • Lowery, C. A., Salzameda, N. T., Sawada, D., Kaufmann, G. F., Janda, K. D. Medicinal chemistry as a conduit for the modulation of quorum sensing Journal of Medicinal Chemistry  2010 53:7467-7489  DOI:10.1021/jm901742c  PMID:20669927  PMCID:PMC2974035
  • Eubanks, L. M., Silhar, P., Salzameda, N. T., Zakhari, J. S., Xiaochuan, F., Barbieri, J. T., Shoemaker, C. B., Hixon, M. S., Janda, K. D. Identification of a natural product antagonist against the botulinum neurotoxin light chain protease ACS Medicinal Chemistry Letters  2010 1:268-272  DOI:10.1021/ml100074s  PMID:20959871  PMCID:PMC2955888
  • Silhar, P., Capkova, K., Salzameda, N. T., Barbieri, J. T., Hixon, M. S., Janda, K. D. Botulinum neurotoxin a protease: Discovery of natural product exosite inhibitors Journal of the American Chemical Society  2010 132:2868-2869  DOI:10.1021/ja910761y  PMID:20158239  PMCID:PMC2832098
  • Salzameda, N. T., Barbieri, J. T., Janda, K. D. Synthetic substrate for application in both high and low throughput assays for botulinum neurotoxin B protease inhibitors Bioorganic & Medicinal Chemistry Letters  2009 19:5848-5850  DOI:10.1016/j.bmcl.2009.08.079  PMID:19747823  PMCID:PMC2753755
  • Capkova, K., Salzameda, N. T., Janda, K. D. Investigations into small molecule non-peptidic inhibitors of the botulinum neurotoxins Toxicon  2009 54:575-582  DOI:10.1016/j.toxicon.2009.03.016  PMID:19327377  PMCID:PMC2730986