recent publications
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academic article
- Nam, T. G., McNamara, C. W., Bopp, S., Dharia, N. V., Meister, S., Bonamy, G. M. C., Plouffe, D. M., Kato, N., McCormack, S., Bursulaya, B., Ke, H. J., Vaidya, A. B., et al. A chemical genomic analysis of decoquinate, a plasmodium falciparum cytochrome b inhibitor ACS Chemical Biology 2011 6:1214-1222 DOI:10.1021/cb200105d PMID:21866942 PMCID:PMC3220786
- Gauba, V., Grunewald, J., Gorney, V., Deaton, L. M., Kang, M. C., Bursulaya, B., Ou, W. J., Lerner, R. A., Schmedt, C., Geierstanger, B. H., Schultz, P. G., Ramirez-Montagut, T. Loss of CD4 T-cell-dependent tolerance to proteins with modified amino acids Proceedings of the National Academy of Sciences of the United States of America 2011 108:12821-12826 DOI:10.1073/pnas.1110042108 PMID:21768354 PMCID:PMC3150954
- Dharia, N. V., Plouffe, D., Bopp, S. E. R., Gonzalez-Paez, G. E., Lucas, C., Salas, C., Soberon, V., Bursulaya, B., Kochel, T. J., Bacon, D. J., Winzeler, E. A. Genome scanning of amazonian plasmodium falciparum shows subtelomeric instability and clindamycin-resistant parasites Genome Research 2010 20:1534-1544 DOI:10.1101/gr.105163.110 PMID:20829224 PMCID:PMC2963817
- Grandl, J., Kim, S. E., Uzzell, V., Bursulaya, B., Petrus, M., Bandell, M., Patapoutian, A. Temperature-induced opening of TRPV1 ion channel is stabilized by the pore domain Nature Neuroscience 2010 13:708-714 DOI:10.1038/nn.2552 PMID:20414199 PMCID:PMC2876202
- Spraggon, G., Hornsby, M., Shipway, A., Tully, D. C., Bursulaya, B., Danahay, H., Harris, J. L., Lesley, S. A. Active site conformational changes of prostasin provide a new mechanism of protease regulation by divalent cations Protein Science 2009 18:1081-1094 DOI:10.1002/pro.118 PMID:19388054 PMCID:PMC2771310
- Kato, N., Sakata, T., Breton, G., Le Roch, K. G., Nagle, A., Andersen, C., Bursulaya, B., Henson, K., Johnson, J., Kumar, K. A., Marr, F., Mason, D., et al. Gene expression signatures and small-molecule compounds link a protein kinase to Plasmodium falciparum motility Nature Chemical Biology 2008 4:347-356 DOI:10.1038/nchembio.87 PMID:18454143
- Xiao, B., Dubin, A. E., Bursulaya, B., Viswanath, V., Jegla, T. J., Patapoutian, A. Identification of transmembrane domain 5 as a critical molecular determinant of menthol sensitivity in mammalian TRPA1 channels Journal of Neuroscience 2008 28:9640-9651 DOI:10.1523/jneurosci.2772-08.2008 PMID:18815250 PMCID:PMC2678945
- Cellitti, S. E., Jones, D. H., Lagpacan, L., Hao, X. S., Zhang, Q., Hu, H. Y., Brittain, S. M., Brinker, A., Caldwell, J., Bursulaya, B., Spraggon, G., Brock, A., et al. In vivo incorporation of unnatural amino acids to probe structure, dynamics, and ligand binding in a large protein by nuclear magnetic resonance spectroscopy Journal of the American Chemical Society 2008 130:9268-9281 DOI:10.1021/ja801602q PMID:18576636 PMCID:PMC2562865
- Grandl, J., Hu, H. Z., Bandell, M., Bursulaya, B., Schmidt, M., Petrus, M., Patapoutian, A. Pore region of TRPV3 ion channel is specifically required for heat activation Nature Neuroscience 2008 11:1007-1013 DOI:10.1038/nn.2169 PMID:19160498 PMCID:PMC2685190
- Epple, R., Azimioara, M., Russo, R., Xie, Y. P., Wang, X., Cow, C., Wityak, J., Karanewsky, D., Bursulaya, B., Kreusch, A., Tuntland, T., Gerken, A., et al. 3,4,5-trisubstituted isoxazoles as novel PPAR delta agonists. Part 2 Bioorganic & Medicinal Chemistry Letters 2006 16:5488-5492 DOI:10.1016/j.bmcl.2006.08.052 PMID:16931011
- Zhang, Z. W., Alfonta, L., Tian, F., Bursulaya, B., Uryu, S., King, D. S., Schultz, P. G. Selective incorporation of 5-hydroxytryptophan into proteins in mammalian cells Proceedings of the National Academy of Sciences of the United States of America 2004 101:8882-8887 DOI:10.1073/pnas.0307029101 PMID:15187228 PMCID:PMC428441
- Wu, T. Y. H., Wagner, K. W., Bursulaya, B., Schultz, P. G., Deveraux, Q. L. Development and characterization of nonpeptidic small molecule inhibitors of the XIAP/caspase-3 interaction Chemistry & Biology 2003 10:759-767 DOI:10.1016/s1074-5521(03)00157-1 PMID:12954335