recent publications

• academic article

  • Li, M., Morris, G. M., Lee, T., Laco, G. S., Wong, C. H., Olson, A. J., Elder, J. H., Wlodawer, A., Gustchina, A. Structural studies of FIV and HIV-1 proteases complexed with all efficient inhibitor of FIV protease Proteins-Structure Function and Genetics  2000 38:29-40  DOI:10.1002/(sici)1097-0134(20000101)38:1<29::aid-prot4>3.0.co;2-n  PMID:10651036
  • Lee, T., Laco, G. S., Torbett, B. E., Fox, H. S., Lerner, D. L., Elder, J. H., Wong, C. H. Analysis of the S3 and S3' subsite specificities of feline immunodeficiency virus (FIV) protease: development of a broad-based protease inhibitor efficacious against FIV, SIV, and HIV in vitro and ex vivo Proceedings of the National Academy of Sciences of the United States of America  1998 95:939-944  DOI:10.1073/pnas.95.3.939  PMID:9448264  PMCID:PMC18632
  • Fitzgerald, M. C., Laco, G. S., Elder, J. H., Kent, S. B. H. A continuous fluorometric assay for the feline immunodeficiency virus protease Analytical Biochemistry  1997 254:226-230  DOI:10.1006/abio.1997.2407  PMID:9417781
  • Laco, G. S., SchalkHihi, C., Lubkowski, J., Morris, G., Zdanov, A., Olson, A., Elder, J. H., Wlodawer, A., Gustchina, A. Crystal structures of the inactive D30N mutant of feline immunodeficiency virus protease complexed with a substrate and an inhibitor Biochemistry  1997 36:10696-10708  DOI:10.1021/bi9707436  PMID:9271500
  • Laco, G. S., Fitzgerald, M. C., Morris, G. M., Olson, A. J., Kent, S. B. H., Elder, J. H. Molecular analysis of the feline immunodeficiency virus protease: generation of a novel form of the protease by autoproteolysis and construction of cleavage-resistant proteases Journal of Virology  1997 71:5505-5511  PMID:9188624  PMCID:PMC191792
  • Prasad, G. S., Stura, E. A., McRee, D. E., Laco, G. S., HasselkusLight, C., Elder, J. H., Stout, C. D. Crystal structure of dutp pyrophosphatase from feline immunodeficiency virus Protein Science  1996 5:2429-2437  DOI:10.1002/pro.5560051205  PMID:8976551  PMCID:PMC2143329
  • Schnolzer, M., Rackwitz, H. R., Gustchina, A., Laco, G. S., Wlodawer, A., Elder, J. H., Kent, S. B. H. Comparative properties of feline immunodeficiency virus (fiv) and human immunodeficiency virus type 1 (hiv-1) proteinases prepared by total chemical synthesis Virology  1996 224:268-275  DOI:10.1006/viro.1996.0528  PMID:8862421