recent publications
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academic article
- Li, M., Morris, G. M., Lee, T., Laco, G. S., Wong, C. H., Olson, A. J., Elder, J. H., Wlodawer, A., Gustchina, A. Structural studies of FIV and HIV-1 proteases complexed with all efficient inhibitor of FIV protease Proteins-Structure Function and Genetics 2000 38:29-40 DOI:10.1002/(sici)1097-0134(20000101)38:1<29::aid-prot4>3.0.co;2-n PMID:10651036
- Lee, T., Laco, G. S., Torbett, B. E., Fox, H. S., Lerner, D. L., Elder, J. H., Wong, C. H. Analysis of the S3 and S3' subsite specificities of feline immunodeficiency virus (FIV) protease: development of a broad-based protease inhibitor efficacious against FIV, SIV, and HIV in vitro and ex vivo Proceedings of the National Academy of Sciences of the United States of America 1998 95:939-944 DOI:10.1073/pnas.95.3.939 PMID:9448264 PMCID:PMC18632
- Fitzgerald, M. C., Laco, G. S., Elder, J. H., Kent, S. B. H. A continuous fluorometric assay for the feline immunodeficiency virus protease Analytical Biochemistry 1997 254:226-230 DOI:10.1006/abio.1997.2407 PMID:9417781
- Laco, G. S., SchalkHihi, C., Lubkowski, J., Morris, G., Zdanov, A., Olson, A., Elder, J. H., Wlodawer, A., Gustchina, A. Crystal structures of the inactive D30N mutant of feline immunodeficiency virus protease complexed with a substrate and an inhibitor Biochemistry 1997 36:10696-10708 DOI:10.1021/bi9707436 PMID:9271500
- Laco, G. S., Fitzgerald, M. C., Morris, G. M., Olson, A. J., Kent, S. B. H., Elder, J. H. Molecular analysis of the feline immunodeficiency virus protease: generation of a novel form of the protease by autoproteolysis and construction of cleavage-resistant proteases Journal of Virology 1997 71:5505-5511 PMID:9188624 PMCID:PMC191792
- Prasad, G. S., Stura, E. A., McRee, D. E., Laco, G. S., HasselkusLight, C., Elder, J. H., Stout, C. D. Crystal structure of dutp pyrophosphatase from feline immunodeficiency virus Protein Science 1996 5:2429-2437 DOI:10.1002/pro.5560051205 PMID:8976551 PMCID:PMC2143329
- Schnolzer, M., Rackwitz, H. R., Gustchina, A., Laco, G. S., Wlodawer, A., Elder, J. H., Kent, S. B. H. Comparative properties of feline immunodeficiency virus (fiv) and human immunodeficiency virus type 1 (hiv-1) proteinases prepared by total chemical synthesis Virology 1996 224:268-275 DOI:10.1006/viro.1996.0528 PMID:8862421