recent publications

• academic article

  • Lee, C. C., Jia, Y., Li, N. X., Sun, X. Y., Ng, K., Ambing, E., Gao, M. Y., Hua, S., Chen, C., Kim, S., Michellys, P. Y., Lesley, S. A., et al. Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain Biochemical Journal  2010 430:425-437  DOI:10.1042/bj20100609  PMID:20632993
  • Han, G. W., Yang, X. L., McMullan, D., Chong, Y. E., Krishna, S. S., Rife, C. L., Weekes, D., Brittain, S. M., Abdubek, P., Ambing, E., Astakhova, T., Axelrod, H. L., et al. Structure of a tryptophanyl-tRNA synthetase containing an iron-sulfur cluster Acta Crystallographica Section F-Structural Biology and Crystallization Communications  2010 66:1326-1334  DOI:10.1107/s1744309110037619  PMID:20944229  PMCID:PMC2954223
  • Xu, Q. P., Sudek, S., McMullan, D., Miller, M. D., Geierstanger, B., Jones, D. H., Krishna, S. S., Spraggon, G., Bursalay, B., Abdubek, P., Acosta, C., Ambing, E., et al. Structural basis of murein peptide specificity of a γ-D-glutamyl-l-diamino acid endopeptidase Structure  2009 17:303-313  DOI:10.1016/j.str.2008.12.008  PMID:19217401  PMCID:PMC2667786
  • Axelrod, H. L., McMullan, D., Krishna, S. S., Miller, M. D., Elsliger, M. A., Abdubek, P., Ambing, E., Astakhova, T., Carlton, D., Chiu, H. J., Clayton, T., Duan, L., et al. Crystal structure of AICAR transformylase IMP cyclohydrolase (TM1249) from Thermotoga maritima at 1.88 Å resolution Proteins-Structure Function and Bioinformatics  2008 71:1042-1049  DOI:10.1002/prot.21967  PMID:18260100
  • Xu, Q. P., Saikatendu, K. S., Krishna, S. S., McMullan, D., Abdubek, P., Agarwalla, S., Ambing, E., Astakhova, T., Axelrod, H. L., Carlton, D., Chiu, H. J., Clayton, T., et al. Crystal structure of MtnX phosphatase from Bacillus subtilis at 2.0 Å resolution provides a structural basis for bipartite phosphomonoester hydrolysis of 2-hydroxy3-keto-5-methylthiopentenyl-1-phosphate Proteins-Structure Function and Bioinformatics  2007 69:433-439  DOI:10.1002/prot.21602  PMID:17654724
  • Krishna, S. S., Tautz, L., Xu, Q. P., McMullan, D., Miller, M. D., Abdubek, P., Ambing, E., Astakhova, T., Axelrod, H. L., Carlton, D., Chiu, H. J., Clayton, T., et al. Crystal structure of NMA 1982 from Neisseria meningiddis at 1.5 Å resolution provides a structural scaffold for nonclassical, eukaryotic-like phosphatases Proteins-Structure Function and Bioinformatics  2007 69:415-421  DOI:10.1002/prot.21314  PMID:17636569
  • Premkumar, L., Rife, C. L., Krishna, S. S., McMullan, D., Miller, M. D., Abdubek, P., Ambing, E., Astakhova, T., Axelrod, H. L., Canaves, J. M., Carlton, D., Chiu, H. J., et al. Crystal structure of TM1030 from THermotoga maritima at 2.3 Å resolution reveals molecular details of its transcription repressor function Proteins-Structure Function and Bioinformatics  2007 68:418-424  DOI:10.1002/prot.21436  PMID:17444523
  • Zubieta, C., Krishna, S. S., McMullan, D., Miller, M. D., Abdubek, P., Agarwalla, S., Ambing, E., Astakhova, T., Axelrod, H. L., Carlton, D., Chiu, H. J., Clayton, T., et al. Crystal structure of homoserine o-succinyltransferase from bacillus cereus at 2.4 Å resolution Proteins-Structure Function and Bioinformatics  2007 68:999-1005  DOI:10.1002/prot.21208  PMID:17546672
  • Zubieta, C., Krishna, S. S., Kapoor, M., Kozbial, P., McMullan, D., Axelrod, H. L., Miller, M. D., Abdubek, P., Ambing, E., Astakhova, T., Carlton, D., Chiu, H. J., et al. Crystal structures of two novel dye-decolorizing peroxidases reveal a β-barrel fold with a conserved heme-binding motif Proteins-Structure Function and Bioinformatics  2007 69:223-233  DOI:10.1002/prot.21550  PMID:17654545
  • Kosloff, M., Han, G. W., Krishna, S. S., Schwarzenbacher, R., Fasnacht, M., Elsliger, M. A., Abdubek, P., Agarwalla, S., Ambing, E., Astakhova, T., Axelrod, H. L., Canaves, J. M., et al. Comparative structural analysis of a novel glutathione S-transferase (ATU5508) from Agrobacterium tumefaciens at 2.0 Å resolution Proteins-Structure Function and Bioinformatics  2006 65:527-537  DOI:10.1002/prot.21130  PMID:16988933
  • DiDonato, M., Krishna, S. S., Schwarzenbacher, R., McMullan, D., Agarwalla, S., Brittain, S. M., Miller, M. D., Abdubek, P., Ambing, E., Axelrod, H. L., Canaves, J. M., Chiu, H. J., et al. Crystal structure of 2-phosphosulfolactate phosphatase (ComB) from Clostridium acetobutylicum at 2.6 Å resolution reveals a new fold with a novel active site Proteins-Structure Function and Bioinformatics  2006 65:771-776  DOI:10.1002/prot.20978  PMID:16927339
  • Jin, K. K., Krishna, S. S., Schwarzenbacher, R., McMullan, D., Abdubek, P., Agarwalla, S., Ambing, E., Axelrod, H., Canaves, J. M., Chiu, H. J., Deacon, A. M., DiDonato, M., et al. Crystal structure of TM1367 from Thermotoga maritima at 1.90 Å resolution reveals an atypical member of the cyclophilin (peptidylprolyl isomerase) fold Proteins-Structure Function and Bioinformatics  2006 63:1112-1118  DOI:10.1002/prot.20894  PMID:16544291
  • DiDonato, M., Krishna, S. S., Schwarzenbacher, R., McMullan, D., Jaroszewski, L., Miller, M. D., Abdubek, M., Agarwalla, S., Ambing, E., Axelrod, H., Biorac, T., Chiu, H. J., et al. Crystal structure of a single-stranded DNA-binding protein (TM0604) from Thermotoga maritima at 2.60 a resolution Proteins-Structure Function and Bioinformatics  2006 63:256-260  DOI:10.1002/prot.20841  PMID:16435371
  • Xu, Q. P., Schwarzenbacher, R., Krishna, S. S., McMullan, D., Agarwalla, S., Quijano, K., Abdubek, P., Ambing, E., Axelrod, H., Biorac, T., Canaves, J. M., Chiu, H. J., et al. Crystal structure of acireductone dioxygenase (ARD) from Mus musculus at 2.06 a resolution Proteins-Structure Function and Bioinformatics  2006 64:808-813  DOI:10.1002/prot.20947  PMID:16783794
  • Xu, Q., Krishna, S. S., McMullan, D., Schwarzenbacher, R., Miller, M. D., Abdubek, P., Agarwalla, S., Ambing, E., Astakhova, T., Axelrod, H. L., Canaves, J. M., Carlton, D., et al. Crystal structure of an ORFan protein (TM1622) from Thermotoga maritima at 1.75 Å resolution reveals a fold similar to the Ran-binding protein Mog1p Proteins-Structure Function and Bioinformatics  2006 65:777-782  DOI:10.1002/prot.21015  PMID:16948158
  • Mathews, II, Krishna, S. S., Schwarzenbacher, R., McMullan, D., Jaroszewski, L., Miller, M. D., Abdubek, P., Agarwalla, S., Ambing, E., Axelrod, H. L., Canaves, J. M., Carlton, D., et al. Crystal structure of phosphoribosylformyl-glycinamidine synthase II, PurS subunit (TM1244) from thermotoga maritima at 1.90 Å resolution Proteins-Structure Function and Bioinformatics  2006 65:249-254  DOI:10.1002/prot.21024  PMID:16865708
  • Mathews, II, Krishna, S. S., Schwarzenbacher, R., McMullan, D., Abdubek, P., Ambing, E., Canaves, J. M., Chiu, H. J., Deacon, A. M., DiDonato, M., Elsliger, M. A., Godzik, A., et al. Crystal structure of phosphoribosylformylglycinamidine synthase II (smPurL) from Thermotoga maritima at 2.15 Å-resolution Proteins-Structure Function and Bioinformatics  2006 63:1106-1111  DOI:10.1002/prot.20650  PMID:16544324
  • Han, G. W., Krishna, S. S., Schwarzenbacher, R., McMullan, D., Ginalski, K., Elsliger, M. A., Brittain, S. M., Abdubek, P., Agarwalla, S., Ambing, E., Astakhova, T., Axelrod, H., et al. Crystal structure of the ApbE protein (TM1553) from Thermotoga maritima at 1.58 Å resolution Proteins-Structure Function and Bioinformatics  2006 64:1083-1090  DOI:10.1002/prot.20950  PMID:16779835
  • Xu, Q. P., Schwarzenbacher, R., McMullan, D., Abdubek, P., Agarwalla, S., Ambing, E., Axelrod, H., Biorac, T., Canaves, J. M., Chin, H. J., Deacon, A. M., DiDonato, M., et al. Crystal structure of virulence factor CJ0248 from Campylobacter jejuni at 2.25 Å resolution reveals a new fold Proteins-Structure Function and Bioinformatics  2006 62:292-296  DOI:10.1002/prot.20611  PMID:16287129
  • Jaroszewski, L., Schwarzenbacher, R., McMullan, D., Abdubek, P., Agarwalla, S., Ambing, E., Axelrod, H., Biorac, T., Canaves, J. M., Chiu, H. J., Deacon, A. M., DiDonato, M., et al. Crystal structure of Hsp33 chaperone (TM1394) from Thermotoga maritima at 2.20 Å resolution Proteins-Structure Function and Bioinformatics  2005 61:669-673  DOI:10.1002/prot.20542  PMID:16167343
  • Mathews, I., Schwarzenbacher, R., McMullan, D., Abdubek, P., Ambing, E., Axelrod, H., Biorac, T., Canaves, J. M., Chiu, H. J., Deacon, C. M., DiDonato, M., Elsliger, M. A., et al. Crystal structure of S-adenosylmethionine : tRNA ribosyltransferase-isomerase (QueA) from Thermotoga maritima at 2.0 A resolution reveals a new fold Proteins-Structure Function and Bioinformatics  2005 59:869-874  DOI:10.1002/prot.20419  PMID:15822125
  • Klock, H. E., Schwarzenbacher, R., Xu, Q. P., McMullan, D., Abdubek, P., Ambing, E., Axelrod, H., Biorac, T., Canaves, J. M., Chiu, H. J., Deacon, A. M., DiDonato, M., et al. Crystal structure of a conserved hypothetical protein (gi : 13879369) from Mouse at 1.90 A resolution reveals a new fold Proteins-Structure Function and Bioinformatics  2005 61:1132-1136  DOI:10.1002/prot.20610  PMID:16224779
  • Xu, Q. P., Schwarzenbacher, R., McMullan, D., Abdubek, P., Ambing, E., Bioac, T., Canaves, J. M., Chiu, H. J., Dai, X. P., Deacon, D. M., DiDonato, M., Elsliger, M. A., et al. Crystal structure of a formiminotetrahydrofolate cyclodeaminase (TM1560) from Thermotoga maritima at 2.80 A resolution reveals a new fold Proteins-Structure Function and Bioinformatics  2005 58:976-981  DOI:10.1002/prot.20364  PMID:15651027
  • Rife, C., Schwarzenbacher, R., McMullan, D., Abdubek, P., Ambing, E., Axelrod, H., Biorac, T., Canaves, J. M., Chiu, H. J., Deacon, A. M., DiDonato, M., Elsliger, M. A., et al. Crystal structure of a putative modulator of DNA gyrase (pmbA) from Thermotoga maritima at 1.95 Å resolution reveals a new fold Proteins-Structure Function and Bioinformatics  2005 61:444-448  DOI:10.1002/prot.20468  PMID:16104019
  • Han, G. W., Schwarzenbacher, R., McMullan, D., Abdubek, P., Ambing, E., Axelrod, H., Biorac, T., Canaves, J. M., Chiu, H. J., Dai, X. P., Deacon, A. M., DiDonato, M., et al. Crystal structure of an Apo mRNA decapping enzyme (DcpS) from mouse at 1.83 Å resolution Proteins-Structure Function and Bioinformatics  2005 60:797-802  DOI:10.1002/prot.20467  PMID:16001405
  • Han, G. W., Schwarzenbacher, R., Page, R., Jaroszewski, L., Abdubek, P., Ambing, E., Biorac, T., Canaves, J. M., Chiu, H. J., Dai, X. P., Deacon, D. M., DiDonato, M., et al. Crystal structure of an alanine-glyoxylate aminotransferase from anabaena sp at 1.70 A resolution reveals a noncovalently linked PLP cofactor Proteins-Structure Function and Bioinformatics  2005 58:971-975  PMID:15657930
  • Arndt, J. W., Schwarzenbacher, R., Page, R., Abdubek, P., Ambing, E., Biorac, T., Canaves, J. M., Chiu, H. J., Dai, X. P., Deacon, A. M., DiDonato, M., Elsliger, M. A., et al. Crystal structure of an alpha/beta serine hydrolase (YDR428C) from Saccharomyces cerevisiae at 1.85 Å resolution Proteins-Structure Function and Bioinformatics  2005 58:755-758  DOI:10.1002/prot.20336  PMID:15624212
  • Levin, I., Miller, M. D., Schwarzenbacher, R., McMullan, D., Abdubek, P., Ambing, E., Biorac, T., Cambell, J., Canaves, J. M., Chiu, C. J., Deacon, A. M., DiDonato, M., et al. Crystal structure of an indigoidine synthase A (IndA)-like protein (TM64) from Thermotoga maritima at 1.90 A resolution reveals a new fold Proteins-Structure Function and Bioinformatics  2005 59:864-868  DOI:10.1002/prot.20420  PMID:15822122
  • Rife, C., Schwarzenbacher, R., McMullan, D., Abdubek, P., Ambing, E., Axelrod, H., Biorac, T., Canaves, J. M., Chiu, H. J., Deacon, A. M., DiDonato, M., Elsliger, M. A., et al. Crystal structure of the global regulatory protein CsrA from Pseudomonas putida at 2.05 Å resolution reveals a new fold Proteins-Structure Function and Bioinformatics  2005 61:449-453  DOI:10.1002/prot.20502  PMID:16104018
  • Levin, I., Schwarzenbacher, R., Page, R., Abdubek, P., Ambing, E., Biorac, T., Brinen, L. S., Campbell, J., Canaves, J. M., Chiu, H. J., Dai, X. P., Deacon, A. M., et al. Crystal structure of a PIN (PilT N-terminus) domain (AF0591) from Archaeoglobus fulgidus at 1.90 A resolution Proteins-Structure Function and Bioinformatics  2004 56:404-408  DOI:10.1002/prot.20090  PMID:15211526
  • McMullan, D., Schwarzenbacher, R., Jaroszewski, L., von Delft, F., Klock, H. E., Vincent, J., Quijano, K., Abdubek, P., Ambing, E., Biorac, T., Brinen, L. S., Canaves, J. M., et al. Crystal structure of a novel Thermotoga maritima enzyme (TM1112) from the cupin family at 1.83 Å resolution Proteins-Structure Function and Bioinformatics  2004 56:615-618  DOI:10.1002/prot.20139  PMID:15229894
  • Schwarzenbacher, R., Jaroszewski, L., Von Delft, F., Abdubek, P., Ambing, E., Biorac, T., Brinen, L. S., Canaves, J. M., Cambell, J., Chiu, H. J., Dai, X. P., Deacon, A. M., et al. Crystal structure of a phosphoribosylaminoimidazole mutase PurE (TM0446) from Thermotoga maritima at 1.77 Å resolution Proteins-Structure Function and Bioinformatics  2004 55:474-478  DOI:10.1002/prot.20023  PMID:15048837
  • Levin, I., Schwarzenbacher, R., McMullan, D., Abdubek, P., Ambing, E., Biorac, T., Cambell, J., Canaves, J. M., Chiu, H. J., Dai, X. P., Deacon, A. M., DiDonato, M., et al. Crystal structure of a putative NADPH-dependent oxidoreductase (GI : 18204011) from mouse at 2.10 Å resolution Proteins-Structure Function and Bioinformatics  2004 56:629-633  DOI:10.1002/prot.20163  PMID:15229897
  • Schwarzenbacher, R., von Delft, F., Abdubek, P., Ambing, E., Biorac, T., Brinen, L. S., Canaves, J. M., Cambell, J., Chiu, H. J., Dai, X. P., Deacon, A. M., DiDonato, M., et al. Crystal structure of a putative PII-like signaling protein (TM0021) from Thermotoga maritima at 2.5 Å resolution Proteins-Structure Function and Bioinformatics  2004 54:810-813  DOI:10.1002/prot.10647  PMID:14997579
  • Schwarzenbacher, R., von Delft, F., Jaroszewski, L., Abdubek, P., Ambing, E., Biorac, T., Brinen, L., Canaves, J. M., Cambell, J., Chiu, H. J., Dai, X. P., Deacon, A. M., et al. Crystal structure of a putative oxalate decarboxylase (TM1287) from Thermotoga maritima at 1.95 A resolution Proteins-Structure Function and Bioinformatics  2004 56:392-395  DOI:10.1002/prot.20016  PMID:15211523
  • Miller, M. D., Schwarzenbacher, R., von Delft, F., Abdubek, P., Ambing, E., Biorac, T., Brinen, L. S., Canaves, J. M., Cambell, J., Chiu, H. J., Dai, X. P., Deacon, A. M., et al. Crystal structure of a tandem cystathionine-beta-synthase (CBS) domain protein (TM0935) from Thermotoga maritima at 1.87 Å resolution Proteins-Structure Function and Bioinformatics  2004 57:213-217  DOI:10.1002/prot.20024  PMID:15326606
  • Schwarzenbacher, R., Jaroszewski, L., von Delft, F., Abdubek, P., Ambing, E., Biorac, T., Brinen, L. S., Canaves, J. M., Cambell, J., Chiu, H. J., Dai, X. P., Deacon, A. M., et al. Crystal structure of a type II quinolic acid phosphoribosyltransferase (TM1645) from Thermotoga maritima at 2.50 Å resolution Proteins-Structure Function and Bioinformatics  2004 55:768-771  DOI:10.1002/prot.20029  PMID:15103640
  • Spraggon, G., Schwarzenbacher, R., Kreusch, A., Lee, C. C., Abdubek, P., Ambing, E., Biorac, T., Brinen, L. S., Canaves, J. M., Cambell, J., Chin, H. J., Dai, X. P., et al. Crystal structure of an Udp-n-acetylmuramate-alanine ligase MurC (TM0231) from Thermotoga maritima at 2.3 Å resolution Proteins-Structure Function and Bioinformatics  2004 55:1078-1081  DOI:10.1002/prot.20034  PMID:15146505
  • Xu, Q. P., Schwarzenbacher, R., Page, R., Sims, E., Abdubek, P., Ambing, E., Biorac, T., Brinen, L. S., Cambell, J., Canaves, J. M., Chiu, H. J., Dai, X. P., et al. Crystal structure of an allantoicase (YIR029W) from Saccharomyces cerevisiae at 2.4 Å resolution Proteins-Structure Function and Bioinformatics  2004 56:619-624  DOI:10.1002/prot.20164  PMID:15229895
  • Schwarzenbacher, R., Jaroszewski, L., von Delft, F., Abdubek, P., Ambing, E., Biorac, T., Brinen, L. S., Canaves, J. M., Cambell, J., Chu, H. J., Dai, X. P., Deacon, A. M., et al. Crystal structure of an aspartate aminotransferase (TM1255) from Thermotoga maritima at 1.90 Å resolution Proteins-Structure Function and Bioinformatics  2004 55:759-763  DOI:10.1002/prot.10646  PMID:15103638