recent publications
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academic article
- Lee, C. C., Jia, Y., Li, N. X., Sun, X. Y., Ng, K., Ambing, E., Gao, M. Y., Hua, S., Chen, C., Kim, S., Michellys, P. Y., Lesley, S. A., et al. Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain Biochemical Journal 2010 430:425-437 DOI:10.1042/bj20100609 PMID:20632993
- Han, G. W., Yang, X. L., McMullan, D., Chong, Y. E., Krishna, S. S., Rife, C. L., Weekes, D., Brittain, S. M., Abdubek, P., Ambing, E., Astakhova, T., Axelrod, H. L., et al. Structure of a tryptophanyl-tRNA synthetase containing an iron-sulfur cluster Acta Crystallographica Section F-Structural Biology and Crystallization Communications 2010 66:1326-1334 DOI:10.1107/s1744309110037619 PMID:20944229 PMCID:PMC2954223
- Xu, Q. P., Sudek, S., McMullan, D., Miller, M. D., Geierstanger, B., Jones, D. H., Krishna, S. S., Spraggon, G., Bursalay, B., Abdubek, P., Acosta, C., Ambing, E., et al. Structural basis of murein peptide specificity of a γ-D-glutamyl-l-diamino acid endopeptidase Structure 2009 17:303-313 DOI:10.1016/j.str.2008.12.008 PMID:19217401 PMCID:PMC2667786
- Axelrod, H. L., McMullan, D., Krishna, S. S., Miller, M. D., Elsliger, M. A., Abdubek, P., Ambing, E., Astakhova, T., Carlton, D., Chiu, H. J., Clayton, T., Duan, L., et al. Crystal structure of AICAR transformylase IMP cyclohydrolase (TM1249) from Thermotoga maritima at 1.88 Å resolution Proteins-Structure Function and Bioinformatics 2008 71:1042-1049 DOI:10.1002/prot.21967 PMID:18260100
- Xu, Q. P., Saikatendu, K. S., Krishna, S. S., McMullan, D., Abdubek, P., Agarwalla, S., Ambing, E., Astakhova, T., Axelrod, H. L., Carlton, D., Chiu, H. J., Clayton, T., et al. Crystal structure of MtnX phosphatase from Bacillus subtilis at 2.0 Å resolution provides a structural basis for bipartite phosphomonoester hydrolysis of 2-hydroxy3-keto-5-methylthiopentenyl-1-phosphate Proteins-Structure Function and Bioinformatics 2007 69:433-439 DOI:10.1002/prot.21602 PMID:17654724
- Krishna, S. S., Tautz, L., Xu, Q. P., McMullan, D., Miller, M. D., Abdubek, P., Ambing, E., Astakhova, T., Axelrod, H. L., Carlton, D., Chiu, H. J., Clayton, T., et al. Crystal structure of NMA 1982 from Neisseria meningiddis at 1.5 Å resolution provides a structural scaffold for nonclassical, eukaryotic-like phosphatases Proteins-Structure Function and Bioinformatics 2007 69:415-421 DOI:10.1002/prot.21314 PMID:17636569
- Premkumar, L., Rife, C. L., Krishna, S. S., McMullan, D., Miller, M. D., Abdubek, P., Ambing, E., Astakhova, T., Axelrod, H. L., Canaves, J. M., Carlton, D., Chiu, H. J., et al. Crystal structure of TM1030 from THermotoga maritima at 2.3 Å resolution reveals molecular details of its transcription repressor function Proteins-Structure Function and Bioinformatics 2007 68:418-424 DOI:10.1002/prot.21436 PMID:17444523
- Zubieta, C., Krishna, S. S., McMullan, D., Miller, M. D., Abdubek, P., Agarwalla, S., Ambing, E., Astakhova, T., Axelrod, H. L., Carlton, D., Chiu, H. J., Clayton, T., et al. Crystal structure of homoserine o-succinyltransferase from bacillus cereus at 2.4 Å resolution Proteins-Structure Function and Bioinformatics 2007 68:999-1005 DOI:10.1002/prot.21208 PMID:17546672
- Zubieta, C., Krishna, S. S., Kapoor, M., Kozbial, P., McMullan, D., Axelrod, H. L., Miller, M. D., Abdubek, P., Ambing, E., Astakhova, T., Carlton, D., Chiu, H. J., et al. Crystal structures of two novel dye-decolorizing peroxidases reveal a β-barrel fold with a conserved heme-binding motif Proteins-Structure Function and Bioinformatics 2007 69:223-233 DOI:10.1002/prot.21550 PMID:17654545
- Kosloff, M., Han, G. W., Krishna, S. S., Schwarzenbacher, R., Fasnacht, M., Elsliger, M. A., Abdubek, P., Agarwalla, S., Ambing, E., Astakhova, T., Axelrod, H. L., Canaves, J. M., et al. Comparative structural analysis of a novel glutathione S-transferase (ATU5508) from Agrobacterium tumefaciens at 2.0 Å resolution Proteins-Structure Function and Bioinformatics 2006 65:527-537 DOI:10.1002/prot.21130 PMID:16988933
- DiDonato, M., Krishna, S. S., Schwarzenbacher, R., McMullan, D., Agarwalla, S., Brittain, S. M., Miller, M. D., Abdubek, P., Ambing, E., Axelrod, H. L., Canaves, J. M., Chiu, H. J., et al. Crystal structure of 2-phosphosulfolactate phosphatase (ComB) from Clostridium acetobutylicum at 2.6 Å resolution reveals a new fold with a novel active site Proteins-Structure Function and Bioinformatics 2006 65:771-776 DOI:10.1002/prot.20978 PMID:16927339
- Jin, K. K., Krishna, S. S., Schwarzenbacher, R., McMullan, D., Abdubek, P., Agarwalla, S., Ambing, E., Axelrod, H., Canaves, J. M., Chiu, H. J., Deacon, A. M., DiDonato, M., et al. Crystal structure of TM1367 from Thermotoga maritima at 1.90 Å resolution reveals an atypical member of the cyclophilin (peptidylprolyl isomerase) fold Proteins-Structure Function and Bioinformatics 2006 63:1112-1118 DOI:10.1002/prot.20894 PMID:16544291
- DiDonato, M., Krishna, S. S., Schwarzenbacher, R., McMullan, D., Jaroszewski, L., Miller, M. D., Abdubek, M., Agarwalla, S., Ambing, E., Axelrod, H., Biorac, T., Chiu, H. J., et al. Crystal structure of a single-stranded DNA-binding protein (TM0604) from Thermotoga maritima at 2.60 a resolution Proteins-Structure Function and Bioinformatics 2006 63:256-260 DOI:10.1002/prot.20841 PMID:16435371
- Xu, Q. P., Schwarzenbacher, R., Krishna, S. S., McMullan, D., Agarwalla, S., Quijano, K., Abdubek, P., Ambing, E., Axelrod, H., Biorac, T., Canaves, J. M., Chiu, H. J., et al. Crystal structure of acireductone dioxygenase (ARD) from Mus musculus at 2.06 a resolution Proteins-Structure Function and Bioinformatics 2006 64:808-813 DOI:10.1002/prot.20947 PMID:16783794
- Xu, Q., Krishna, S. S., McMullan, D., Schwarzenbacher, R., Miller, M. D., Abdubek, P., Agarwalla, S., Ambing, E., Astakhova, T., Axelrod, H. L., Canaves, J. M., Carlton, D., et al. Crystal structure of an ORFan protein (TM1622) from Thermotoga maritima at 1.75 Å resolution reveals a fold similar to the Ran-binding protein Mog1p Proteins-Structure Function and Bioinformatics 2006 65:777-782 DOI:10.1002/prot.21015 PMID:16948158
- Mathews, II, Krishna, S. S., Schwarzenbacher, R., McMullan, D., Jaroszewski, L., Miller, M. D., Abdubek, P., Agarwalla, S., Ambing, E., Axelrod, H. L., Canaves, J. M., Carlton, D., et al. Crystal structure of phosphoribosylformyl-glycinamidine synthase II, PurS subunit (TM1244) from thermotoga maritima at 1.90 Å resolution Proteins-Structure Function and Bioinformatics 2006 65:249-254 DOI:10.1002/prot.21024 PMID:16865708
- Mathews, II, Krishna, S. S., Schwarzenbacher, R., McMullan, D., Abdubek, P., Ambing, E., Canaves, J. M., Chiu, H. J., Deacon, A. M., DiDonato, M., Elsliger, M. A., Godzik, A., et al. Crystal structure of phosphoribosylformylglycinamidine synthase II (smPurL) from Thermotoga maritima at 2.15 Å-resolution Proteins-Structure Function and Bioinformatics 2006 63:1106-1111 DOI:10.1002/prot.20650 PMID:16544324
- Han, G. W., Krishna, S. S., Schwarzenbacher, R., McMullan, D., Ginalski, K., Elsliger, M. A., Brittain, S. M., Abdubek, P., Agarwalla, S., Ambing, E., Astakhova, T., Axelrod, H., et al. Crystal structure of the ApbE protein (TM1553) from Thermotoga maritima at 1.58 Å resolution Proteins-Structure Function and Bioinformatics 2006 64:1083-1090 DOI:10.1002/prot.20950 PMID:16779835
- Xu, Q. P., Schwarzenbacher, R., McMullan, D., Abdubek, P., Agarwalla, S., Ambing, E., Axelrod, H., Biorac, T., Canaves, J. M., Chin, H. J., Deacon, A. M., DiDonato, M., et al. Crystal structure of virulence factor CJ0248 from Campylobacter jejuni at 2.25 Å resolution reveals a new fold Proteins-Structure Function and Bioinformatics 2006 62:292-296 DOI:10.1002/prot.20611 PMID:16287129
- Jaroszewski, L., Schwarzenbacher, R., McMullan, D., Abdubek, P., Agarwalla, S., Ambing, E., Axelrod, H., Biorac, T., Canaves, J. M., Chiu, H. J., Deacon, A. M., DiDonato, M., et al. Crystal structure of Hsp33 chaperone (TM1394) from Thermotoga maritima at 2.20 Å resolution Proteins-Structure Function and Bioinformatics 2005 61:669-673 DOI:10.1002/prot.20542 PMID:16167343
- Mathews, I., Schwarzenbacher, R., McMullan, D., Abdubek, P., Ambing, E., Axelrod, H., Biorac, T., Canaves, J. M., Chiu, H. J., Deacon, C. M., DiDonato, M., Elsliger, M. A., et al. Crystal structure of S-adenosylmethionine : tRNA ribosyltransferase-isomerase (QueA) from Thermotoga maritima at 2.0 A resolution reveals a new fold Proteins-Structure Function and Bioinformatics 2005 59:869-874 DOI:10.1002/prot.20419 PMID:15822125
- Klock, H. E., Schwarzenbacher, R., Xu, Q. P., McMullan, D., Abdubek, P., Ambing, E., Axelrod, H., Biorac, T., Canaves, J. M., Chiu, H. J., Deacon, A. M., DiDonato, M., et al. Crystal structure of a conserved hypothetical protein (gi : 13879369) from Mouse at 1.90 A resolution reveals a new fold Proteins-Structure Function and Bioinformatics 2005 61:1132-1136 DOI:10.1002/prot.20610 PMID:16224779
- Xu, Q. P., Schwarzenbacher, R., McMullan, D., Abdubek, P., Ambing, E., Bioac, T., Canaves, J. M., Chiu, H. J., Dai, X. P., Deacon, D. M., DiDonato, M., Elsliger, M. A., et al. Crystal structure of a formiminotetrahydrofolate cyclodeaminase (TM1560) from Thermotoga maritima at 2.80 A resolution reveals a new fold Proteins-Structure Function and Bioinformatics 2005 58:976-981 DOI:10.1002/prot.20364 PMID:15651027
- Rife, C., Schwarzenbacher, R., McMullan, D., Abdubek, P., Ambing, E., Axelrod, H., Biorac, T., Canaves, J. M., Chiu, H. J., Deacon, A. M., DiDonato, M., Elsliger, M. A., et al. Crystal structure of a putative modulator of DNA gyrase (pmbA) from Thermotoga maritima at 1.95 Å resolution reveals a new fold Proteins-Structure Function and Bioinformatics 2005 61:444-448 DOI:10.1002/prot.20468 PMID:16104019
- Han, G. W., Schwarzenbacher, R., McMullan, D., Abdubek, P., Ambing, E., Axelrod, H., Biorac, T., Canaves, J. M., Chiu, H. J., Dai, X. P., Deacon, A. M., DiDonato, M., et al. Crystal structure of an Apo mRNA decapping enzyme (DcpS) from mouse at 1.83 Å resolution Proteins-Structure Function and Bioinformatics 2005 60:797-802 DOI:10.1002/prot.20467 PMID:16001405
- Han, G. W., Schwarzenbacher, R., Page, R., Jaroszewski, L., Abdubek, P., Ambing, E., Biorac, T., Canaves, J. M., Chiu, H. J., Dai, X. P., Deacon, D. M., DiDonato, M., et al. Crystal structure of an alanine-glyoxylate aminotransferase from anabaena sp at 1.70 A resolution reveals a noncovalently linked PLP cofactor Proteins-Structure Function and Bioinformatics 2005 58:971-975 PMID:15657930
- Arndt, J. W., Schwarzenbacher, R., Page, R., Abdubek, P., Ambing, E., Biorac, T., Canaves, J. M., Chiu, H. J., Dai, X. P., Deacon, A. M., DiDonato, M., Elsliger, M. A., et al. Crystal structure of an alpha/beta serine hydrolase (YDR428C) from Saccharomyces cerevisiae at 1.85 Å resolution Proteins-Structure Function and Bioinformatics 2005 58:755-758 DOI:10.1002/prot.20336 PMID:15624212
- Levin, I., Miller, M. D., Schwarzenbacher, R., McMullan, D., Abdubek, P., Ambing, E., Biorac, T., Cambell, J., Canaves, J. M., Chiu, C. J., Deacon, A. M., DiDonato, M., et al. Crystal structure of an indigoidine synthase A (IndA)-like protein (TM64) from Thermotoga maritima at 1.90 A resolution reveals a new fold Proteins-Structure Function and Bioinformatics 2005 59:864-868 DOI:10.1002/prot.20420 PMID:15822122
- Rife, C., Schwarzenbacher, R., McMullan, D., Abdubek, P., Ambing, E., Axelrod, H., Biorac, T., Canaves, J. M., Chiu, H. J., Deacon, A. M., DiDonato, M., Elsliger, M. A., et al. Crystal structure of the global regulatory protein CsrA from Pseudomonas putida at 2.05 Å resolution reveals a new fold Proteins-Structure Function and Bioinformatics 2005 61:449-453 DOI:10.1002/prot.20502 PMID:16104018
- Levin, I., Schwarzenbacher, R., Page, R., Abdubek, P., Ambing, E., Biorac, T., Brinen, L. S., Campbell, J., Canaves, J. M., Chiu, H. J., Dai, X. P., Deacon, A. M., et al. Crystal structure of a PIN (PilT N-terminus) domain (AF0591) from Archaeoglobus fulgidus at 1.90 A resolution Proteins-Structure Function and Bioinformatics 2004 56:404-408 DOI:10.1002/prot.20090 PMID:15211526
- McMullan, D., Schwarzenbacher, R., Jaroszewski, L., von Delft, F., Klock, H. E., Vincent, J., Quijano, K., Abdubek, P., Ambing, E., Biorac, T., Brinen, L. S., Canaves, J. M., et al. Crystal structure of a novel Thermotoga maritima enzyme (TM1112) from the cupin family at 1.83 Å resolution Proteins-Structure Function and Bioinformatics 2004 56:615-618 DOI:10.1002/prot.20139 PMID:15229894
- Schwarzenbacher, R., Jaroszewski, L., Von Delft, F., Abdubek, P., Ambing, E., Biorac, T., Brinen, L. S., Canaves, J. M., Cambell, J., Chiu, H. J., Dai, X. P., Deacon, A. M., et al. Crystal structure of a phosphoribosylaminoimidazole mutase PurE (TM0446) from Thermotoga maritima at 1.77 Å resolution Proteins-Structure Function and Bioinformatics 2004 55:474-478 DOI:10.1002/prot.20023 PMID:15048837
- Levin, I., Schwarzenbacher, R., McMullan, D., Abdubek, P., Ambing, E., Biorac, T., Cambell, J., Canaves, J. M., Chiu, H. J., Dai, X. P., Deacon, A. M., DiDonato, M., et al. Crystal structure of a putative NADPH-dependent oxidoreductase (GI : 18204011) from mouse at 2.10 Å resolution Proteins-Structure Function and Bioinformatics 2004 56:629-633 DOI:10.1002/prot.20163 PMID:15229897
- Schwarzenbacher, R., von Delft, F., Abdubek, P., Ambing, E., Biorac, T., Brinen, L. S., Canaves, J. M., Cambell, J., Chiu, H. J., Dai, X. P., Deacon, A. M., DiDonato, M., et al. Crystal structure of a putative PII-like signaling protein (TM0021) from Thermotoga maritima at 2.5 Å resolution Proteins-Structure Function and Bioinformatics 2004 54:810-813 DOI:10.1002/prot.10647 PMID:14997579
- Schwarzenbacher, R., von Delft, F., Jaroszewski, L., Abdubek, P., Ambing, E., Biorac, T., Brinen, L., Canaves, J. M., Cambell, J., Chiu, H. J., Dai, X. P., Deacon, A. M., et al. Crystal structure of a putative oxalate decarboxylase (TM1287) from Thermotoga maritima at 1.95 A resolution Proteins-Structure Function and Bioinformatics 2004 56:392-395 DOI:10.1002/prot.20016 PMID:15211523
- Miller, M. D., Schwarzenbacher, R., von Delft, F., Abdubek, P., Ambing, E., Biorac, T., Brinen, L. S., Canaves, J. M., Cambell, J., Chiu, H. J., Dai, X. P., Deacon, A. M., et al. Crystal structure of a tandem cystathionine-beta-synthase (CBS) domain protein (TM0935) from Thermotoga maritima at 1.87 Å resolution Proteins-Structure Function and Bioinformatics 2004 57:213-217 DOI:10.1002/prot.20024 PMID:15326606
- Schwarzenbacher, R., Jaroszewski, L., von Delft, F., Abdubek, P., Ambing, E., Biorac, T., Brinen, L. S., Canaves, J. M., Cambell, J., Chiu, H. J., Dai, X. P., Deacon, A. M., et al. Crystal structure of a type II quinolic acid phosphoribosyltransferase (TM1645) from Thermotoga maritima at 2.50 Å resolution Proteins-Structure Function and Bioinformatics 2004 55:768-771 DOI:10.1002/prot.20029 PMID:15103640
- Spraggon, G., Schwarzenbacher, R., Kreusch, A., Lee, C. C., Abdubek, P., Ambing, E., Biorac, T., Brinen, L. S., Canaves, J. M., Cambell, J., Chin, H. J., Dai, X. P., et al. Crystal structure of an Udp-n-acetylmuramate-alanine ligase MurC (TM0231) from Thermotoga maritima at 2.3 Å resolution Proteins-Structure Function and Bioinformatics 2004 55:1078-1081 DOI:10.1002/prot.20034 PMID:15146505
- Xu, Q. P., Schwarzenbacher, R., Page, R., Sims, E., Abdubek, P., Ambing, E., Biorac, T., Brinen, L. S., Cambell, J., Canaves, J. M., Chiu, H. J., Dai, X. P., et al. Crystal structure of an allantoicase (YIR029W) from Saccharomyces cerevisiae at 2.4 Å resolution Proteins-Structure Function and Bioinformatics 2004 56:619-624 DOI:10.1002/prot.20164 PMID:15229895
- Schwarzenbacher, R., Jaroszewski, L., von Delft, F., Abdubek, P., Ambing, E., Biorac, T., Brinen, L. S., Canaves, J. M., Cambell, J., Chu, H. J., Dai, X. P., Deacon, A. M., et al. Crystal structure of an aspartate aminotransferase (TM1255) from Thermotoga maritima at 1.90 Å resolution Proteins-Structure Function and Bioinformatics 2004 55:759-763 DOI:10.1002/prot.10646 PMID:15103638