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The antiquity of RNA-based evolution

Academic Article
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Overview

authors

  • Joyce, Gerald

publication date

  • 2002

journal

  • Nature  Journal

abstract

  • All life that is known to exist on Earth today and all life for which there is evidence in the geological record seems to be of the same form--one based on DNA genomes and protein enzymes. Yet there are strong reasons to conclude that DNA- and protein-based life was preceded by a simpler life form based primarily on RNA. This earlier era is referred to as the 'RNA world', during which the genetic information resided in the sequence of RNA molecules and the phenotype derived from the catalytic properties of RNA.

subject areas

  • Biological Evolution
  • Catalysis
  • DNA
  • Models, Chemical
  • Nucleic Acid Conformation
  • Origin of Life
  • Proteins
  • RNA
  • RNA, Catalytic
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Identity

International Standard Serial Number (ISSN)

  • 0028-0836

Digital Object Identifier (DOI)

  • 10.1038/418214a

PubMed ID

  • 12110897
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Additional Document Info

start page

  • 214

end page

  • 221

volume

  • 418

issue

  • 6894

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