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Evans, R. M.

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    • Zhuang, L., Hulin, J. A., Gromova, A., Nguyen, T. D. T., Yu, R. T., Liddle, C., Downes, M., Evans, R. M., Makarenkova, H. P., Meech, R. Barx2 and Pax7 have antagonistic functions in regulation of wnt signaling and satellite cell differentiation Stem Cells  2014 32:1661-1673  DOI:10.1002/stem.1674  PMID:24753152  PMCID:PMC4134105
    • Panopoulos, A. D., Yanes, O., Ruiz, S., Kida, Y. S., Diep, D., Tautenhahn, R., Herrerias, A., Batchelder, E. M., Plongthongkum, N., Lutz, M., Berggren, W. T., Zhang, K., et al. The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming Cell Research  2012 22:168-177  DOI:10.1038/cr.2011.177  PMID:22064701  PMCID:PMC3252494
    • Lamia, K. A., Papp, S. J., Yu, R. T., Barish, G. D., Uhlenhaut, N. H., Jonker, J. W., Downes, M., Evans, R. M. Cryptochromes mediate rhythmic repression of the glucocorticoid receptor Nature  2011 480:552-556  DOI:10.1038/nature10700  PMID:22170608  PMCID:PMC3245818
    • Krebs, P., Fan, W. W., Chen, Y. H., Tobita, K., Downes, M. R., Wood, M. R., Sun, L., Li, X. H., Xia, Y., Ding, N., Spaeth, J. M., Moresco, E. M. Y., et al. Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet Proceedings of the National Academy of Sciences of the United States of America  2011 108:19678-19682  DOI:10.1073/pnas.1117835108  PMID:22106289  PMCID:PMC3241770
    • Lamia, K. A., Evans, R. M. Metabolism: Tick, tock, a beta-cell clock Nature  2010 466:571-572  DOI:10.1038/466571a  PMID:20671699  PMCID:PMC3610560
    • Lamia, K. A., Sachdeva, U. M., DiTacchio, L., Williams, E. C., Alvarez, J. G., Egan, D. F., Vasquez, D. S., Juguilon, H., Panda, S., Shaw, R. J., Thompson, C. B., Evans, R. M. AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation Science  2009 326:437-440  DOI:10.1126/science.1172156  PMID:19833968  PMCID:PMC2819106
    • Barish, G. D., Atkins, A. R., Downes, M., Olson, P., Chong, L. W., Nelson, M., Zou, Y., Hwang, H., Kang, H., Curtiss, L., Evans, R. M., Lee, C. H. PPAR delta regulates multiple proinflammatory pathways to suppress atherosclerosis Proceedings of the National Academy of Sciences of the United States of America  2008 105:4271-4276  DOI:10.1073/pnas.0711875105  PMID:18337509  PMCID:PMC2393796
    • Wan, Y. H., Saghatelian, A., Chong, L. W., Zhang, C. L., Cravatt, B. F., Evans, R. M. Maternal PPAR gamma protects nursing neonates by suppressing the production of inflammatory milk Genes & Development  2007 21:1895-1908  DOI:10.1101/gad.1567207  PMID:17652179  PMCID:PMC1935028
    • Yang, X., Lamia, K. A., Evans, R. M. Nuclear receptors, metabolism, and the circadian clock Cold Spring Harbor Symposia on Quantitative Biology  2007 72:387-394  DOI:10.1101/sqb.2007.72.058  PMID:18419296
    • Qi, L., Heredia, J. E., Altarejos, J. Y., Screaton, R., Goebel, N., Niessen, S., MacLeod, I. X., Liew, C. W., Kulkarni, R. N., Bain, J., Newgard, C., Nelson, M., et al. TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism Science  2006 312:1763-1766  DOI:10.1126/science.1123374  PMID:16794074
    • Li, Z., Chen, W. R., Hale, J. J., Lynch, C. L., Mills, S. G., Hajdu, R., Keohane, C. A., Rosenbach, M. J., Milligan, J. A., Shei, G. J., Chrebet, G., Parent, S. A., et al. Discovery of potent 3,5-diphenyl-1,2,4-oxadiazole sphingosine-1-phosphate-1 (s1p(1)) receptor agonists with exceptional selectivity against s1p(2) and s1p(3) Journal of Medicinal Chemistry  2005 48:6169-6173  DOI:10.1021/jm0503244  PMID:16190743
    • Galimi, F., Saez, E., Gall, J., Hoong, N., Cho, G., Evans, R. M., Verma, I. M. Development of ecdysone-regulated lentiviral vectors Molecular Therapy  2005 11:142-148  DOI:10.1016/j.ymthe.2004.08.021  PMID:15585415
    • Saez, E., Rosenfeld, J., Livolsi, A., Olson, P., Lombardo, E., Nelson, M., Banayo, E., Cardiff, R. D., Izpisua-Belmonte, J. C., Evans, R. M. Ppar gamma signaling exacerbates mammary gland tumor development Genes & Development  2004 18:528-540  DOI:10.1101/gad.1167804  PMID:15037548  PMCID:PMC374235
    • Xu, W., Cho, H., Kadam, S., Banayo, E. M., Anderson, S., Yates, J. R., Emerson, B. M., Evans, R. M. A methylation-mediator complex in hormone signaling Genes & Development  2004 18:144-156  DOI:10.1101/gad.1141704  PMID:14729568  PMCID:PMC324421
    • Demarest, S. J., Deechongkit, S., Dyson, H. J., Evans, R. M., Wright, P. E. Packing, specificity, and mutability at the binding interface between the p160 coactivator and creb-binding protein Protein Science  2004 13:203-210  DOI:10.1110/ps.03366504  PMID:14691235  PMCID:PMC2286511
    • Saez, E., Olson, P., Evans, R. M. Genetic deficiency in pparg does not alter development of experimental prostate cancer Nature Medicine  2003 9:1265-1266  DOI:10.1038/nm928  PMID:12960963
    • Gearhart, M. D., Holmbeck, S. M. A., Evans, R. M., Dyson, H. J., Wright, P. E. Monomeric complex of human orphan estrogen related receptor-2 with DNA: A pseudo-dimer interface mediates extended half-site recognition Journal of Molecular Biology  2003 327:819-832  DOI:10.1016/s0022-2836(03)00183-9  PMID:12654265
    • Downes, M., Verdecia, M. A., Roecker, A. J., Hughes, R., Hogenesch, J. B., Kast-Woelbern, H. R., Bowman, M. E., Ferrer, J. L., Anisfeld, A. M., Edwards, P. A., Rosenfeld, J. M., Alvarez, J. G. A., et al. A chemical, genetic, and structural analysis of the nuclear bile acid receptor fxr Molecular Cell  2003 11:1079-1092  DOI:10.1016/s1097-2765(03)00104-7  PMID:12718892
    • Nicolaou, K. C., Evans, R. M., Roecker, A. J., Hughes, R., Downes, M., Pfefferkorn, J. A. Discovery and optimization of non-steroidal FXR agonists from natural product-like libraries Organic & Biomolecular Chemistry  2003 1:908-920  DOI:10.1039/b300525a  PMID:12929628
    • Demarest, S. J., Martinez-Yamout, M., Chung, J., Chen, H. W., Xu, W., Dyson, H. J., Evans, R. M., Wright, P. E. Mutual synergistic folding in recruitment of cbp/p300 by p160 nuclear receptor coactivators Nature  2002 415:549-553  DOI:10.1038/415549a  PMID:11823864
    • Xu, W., Chen, H. W., Du, K. Y., Asahara, H., Tini, M., Emerson, B. M., Montminy, M., Evans, R. M. A transcriptional switch mediated by cofactor methylation Science  2001 294:2507-2511  DOI:10.1126/science.1065961  PMID:11701890
    • Chawla, A., Boisvert, W. A., Lee, C. H., Laffitte, B. A., Barak, Y., Joseph, S. B., Liao, D., Nagy, L., Edwards, P. A., Curtiss, L. K., Evans, R. M., Tontonoz, P. A ppar gamma-lxr-abca1 pathway in macrophages is involved in cholesterol efflux and atherogenesis Molecular Cell  2001 7:161-171  DOI:10.1016/s1097-2765(01)00164-2  PMID:11172721
    • Saez, E., Nelson, M. C., Eshelman, B., Banayo, E., Koder, A., Cho, G. J., Evans, R. M. Identification of ligands and coligands for the ecdysone-regulated gene switch Proceedings of the National Academy of Sciences of the United States of America  2000 97:14512-14517  DOI:10.1073/pnas.260499497  PMID:11114195  PMCID:PMC18950
    • Chawla, A., Saez, E., Evans, R. M. "Don't know much bile-ology" Cell  2000 103:1-4  DOI:10.1016/s0092-8674(00)00097-0  PMID:11051540
    • Asahara, H., Dutta, S., Kao, H. Y., Evans, R. M., Montminy, M. Pbx-hox heterodimers recruit coactivator-corepressor complexes in an isoform-specific manner Molecular and Cellular Biology  1999 19:8219-8225  PMID:10567547  PMCID:PMC84906
    • Saez, E., Tontonoz, P., Nelson, M. C., Alvarez, J. G. A., U, T. M., Baird, S. M., Thomazy, V. A., Evans, R. M. Activators of the nuclear receptor ppar gamma enhance colon polyp formation Nature Medicine  1998 4:1058-1061  DOI:10.1038/2042  PMID:9734400
    • Saez, E., No, D., West, A., Evans, R. M. Inducible gene expression in mammalian cells and transgenic mice Current Opinion in Biotechnology  1997 8:608-616  DOI:10.1016/s0958-1669(97)80037-7  PMID:9353233
    • Sem, D. S., Casimiro, D. R., Kliewer, S. A., Provencal, J., Evans, R. M., Wright, P. E. Nmr spectroscopic studies of the DNA-binding domain of the monomer-binding nuclear orphan receptor, human estrogen related receptor-2 - the carboxyl-terminal extension to the zinc-finger region is unstructured in the free form of the protein Journal of Biological Chemistry  1997 272:18038-18043  DOI:10.1074/jbc.272.29.18038  PMID:9218433
    • Lee, M. S., Sem, D. S., Kliewer, S. A., Provencal, J., Evans, R. M., Wright, P. E. Nmr assignments and secondary structure of the retinoid-x receptor-alpha DNA-binding domain - evidence for the novel c-terminal helix European Journal of Biochemistry  1994 224:639-650  DOI:10.1111/j.1432-1033.1994.00639.x  PMID:7925381
    • Lee, M. S., Kliewer, S. A., Provencal, J., Wright, P. E., Evans, R. M. Structure of the retinoid-x receptor-alpha DNA-binding domain - a helix required for homodimeric DNA-binding Science  1993 260:1117-1121  DOI:10.1126/science.8388124  PMID:8388124

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