recent publications
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academic article
- Cheng, B. Y. H., Ortiz-Riano, E., de la Torre, J. C., Martinez-Sobrido, L. Arenavirus genome rearrangement for the development of live attenuated vaccines Journal of Virology 2015 89:7373-7384 DOI:10.1128/jvi.00307-15 PMID:25972555 PMCID:PMC4473541
- Pythoud, C., Rothenberger, S., Martinez-Sobrido, L., de la Torre, J. C., Kunz, S. Lymphocytic choriomeningitis virus differentially affects the virus-induced type I interferon response and mitochondrial apoptosis mediated by RIG-I/MAVS Journal of Virology 2015 89:6240-6250 DOI:10.1128/jvi.00610-15 PMID:25833049
- Cheng, B. Y. H., Ortiz-Riano, E., Nogales, A., de la Torre, J. C., Martinez-Sobrido, L. Development of live-attenuated arenavirus vaccines based on codon deoptimization Journal of Virology 2015 89:3523-3533 DOI:10.1128/jvi.03401-14 PMID:25589652
- Ortiz-Riano, E., Ngo, N., Devito, S., Eggink, D., Munger, J., Shaw, M. L., de la Torre, J. C., Martinez-Sobrido, L. Inhibition of arenavirus by A3, a pyrimidine biosynthesis inhibitor Journal of Virology 2014 88:878-889 DOI:10.1128/jvi.02275-13 PMID:24198417 PMCID:PMC3911634
- Ortiz-Riano, E., Cheng, B. Y. H., de la Torre, J. C., Martinez-Sobrido, L. Arenavirus reverse genetics for vaccine development Journal of General Virology 2013 94:1175-1188 DOI:10.1099/vir.0.051102-0 PMID:23364194 PMCID:PMC3709625
- Ortiz-Riano, E., Cheng, B. Y. H., de la Torre, J. C., Martinez-Sobrido, L. D471G mutation in LCMV-NP affects its ability to self-associate and results in a dominant negative effect in viral RNA synthesis Viruses-Basel 2012 4:2137-2161 DOI:10.3390/v4102137 PMID:23202457 PMCID:PMC3497045
- Pythoud, C., Rodrigo, Wwsi, Pasqual, G., Rothenberger, S., Martinez-Sobrido, L., de la Torre, J. C., Kunz, S. Arenavirus nucleoprotein targets interferon regulatory factor-activating kinase IKK epsilon Journal of Virology 2012 86:7728-7738 DOI:10.1128/jvi.00187-12 PMID:22532683 PMCID:PMC3421673
- Rodrigo, Wwsi, Ortiz-Riano, E., Pythoud, C., Kunz, S., de la Torre, J. C., Martinez-Sobrido, L. Arenavirus nucleoproteins prevent activation of nuclear factor kappa b Journal of Virology 2012 86:8185-8197 DOI:10.1128/jvi.07240-11 PMID:22623788 PMCID:PMC3421694
- Ortiz-Riano, E., Cheng, B. Y. H., de la Torre, J. C., Martinez-Sobrido, L. Self-association of lymphocytic choriomeningitis virus nucleoprotein is mediated by its N-terminal region and is not required for its anti-interferon function Journal of Virology 2012 86:3307-3317 DOI:10.1128/jvi.05503-11 PMID:22258244 PMCID:PMC3302321
- Ortiz-Riano, E., Cheng, B. Y. H., de la Torre, J. C., Martinez-Sobrido, L. The C-terminal region of lymphocytic choriomeningitis virus nucleoprotein contains distinct and segregable functional domains involved in NP-Z interaction and counteraction of the type I interferon response Journal of Virology 2011 85:13038-13048 DOI:10.1128/jvi.05834-11 PMID:21976642 PMCID:PMC3233175
- Rodrigo, Wwsi, de la Torre, J. C., Martinez-Sobrido, L. Use of single-cycle infectious lymphocytic choriomeningitis virus to study hemorrhagic fever arenaviruses Journal of Virology 2011 85:1684-1695 DOI:10.1128/jvi.02229-10 PMID:21123370 PMCID:PMC3028880
- Borrow, P., Martinez-Sobrido, L., de la Torre, J. C. Inhibition of the type I interferon antiviral response during arenavirus infection Viruses-Basel 2010 2:2443-2480 DOI:10.3390/v2112443 PMID:21994626 PMCID:PMC3185579
- Martinez-Sobrido, L., Emonet, S., Giannakas, P., Cubitt, B., Garcia-Sastre, A., de la Torre, J. C. Identification of amino acid residues critical for the anti-interferon activity of the nucleoprotein of the prototypic arenavirus lymphocytic choriomeningitis virus Journal of Virology 2009 83:11330-11340 DOI:10.1128/jvi.00763-09 PMID:19710144 PMCID:PMC2772779
- Martinez-Sobrido, L., Giannakas, P., Cubitt, B., Garcia-Sastre, A., de la Torre, J. C. Differential inhibition of type I interferon induction by arenavirus nucleoproteins Journal of Virology 2007 81:12696-12703 DOI:10.1128/jvi.00882-07 PMID:17804508
- Martinez-Sobrido, L., Zuniga, E. I., Rosario, D., Garcia-Sastre, A., de la Torre, J. C. Inhibition of the type I interferon response by the nucleoprotein of the prototypic arenavirus lymphocytic choriomeningitis virus Journal of Virology 2006 80:9192-9199 DOI:10.1128/jvi.00555-06 PMID:16940530
- Cardenas, W. B., Loo, Y. M., Gale, M., Hartman, A. L., Kimberlin, C. R., Martinez-Sobrido, L., Saphire, E. O., Basler, C. F. Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling Journal of Virology 2006 80:5168-5178 DOI:10.1128/jvi.02199-05 PMID:16698997