related to degree

• Michaudel, Quentin, Ph.D. in Organic Chemistry, Scripps Research 2010 - 2015

authors

• Michaudel, Quentin
• Thevenet, D.
• Baran, Phil

publication date

• 2012

journal

• Journal of the American Chemical Society  Journal

abstract

• Intermolecular Ritter-type C-H amination of unactivated sp(3) carbons has been developed. This new reaction proceeds under mild conditions using readily available reagents and an inexpensive source of nitrogen (acetonitrile). A broad scope of substrates can be aminated with this method since many functional groups are tolerated. This reaction also allows for the direct, innate C-H amination of a variety of hydrocarbons such as cyclohexane without the need of prefunctionalization or installation of a directing group.

subject areas

• Alcohols
• Amides
• Amination
• Amines
• Hydrocarbons
• Ketones
• Molecular Structure
• Stereoisomerism

PubMed Central ID

• PMC3277284

International Standard Serial Number (ISSN)

• 0002-7863

Digital Object Identifier (DOI)

• 10.1021/ja212020b

PubMed ID

• 22276612

start page

• 2547

end page

• 2550

volume

• 134

issue

• 5