recent publications

• academic article

  • Pancera, M., Shahzad-ul-Hussan, S., Doria-Rose, N. A., McLellan, J. S., Bailer, R. T., Dai, K., Loesgen, S., Louder, M. K., Staupe, R. P., Yang, Y., Zhang, B., Parks, R., et al. Structural basis for diverse N-glycan recognition by HIV-1-neutralizing V1-V2-directed antibody PG16 Nature Structural & Molecular Biology  2013 20:804-813  DOI:10.1038/nsmb.2600  PMID:23708607  PMCID:PMC4046252
  • Kwon, Y. D., Finzi, A., Wu, X., Dogo-Isonagie, C., Lee, L. K., Moore, L. R., Schmidt, S. D., Stuckey, J., Yang, Y., Zhou, T., Zhu, J., Vicic, D. A., et al. Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops Proceedings of the National Academy of Sciences of the United States of America  2012 109:5663-5668  DOI:10.1073/pnas.1112391109  PMID:22451932  PMCID:PMC3326499
  • McLellan, J. S., Pancera, M., Carrico, C., Gorman, J., Julien, J. P., Khayat, R., Louder, R., Pejchal, R., Sastry, M., Dai, K. F., O'Dell, S., Patel, N., et al. Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9 Nature  2011 480:336-343  DOI:10.1038/nature10696  PMID:22113616  PMCID:PMC3406929
  • Lam, S. N., Acharya, P., Wyatt, R., Kwong, P. D., Bewley, C. A. Tyrosine-sulfate isosteres of ccr5 n-terminus as tools for studying hiv-1 entry Bioorganic & Medicinal Chemistry  2008 16:10113-10120  DOI:10.1016/j.bmc.2008.10.005  PMID:18952441  PMCID:PMC2650494
  • Nelson, J. D., Kinkead, H., Brunel, F. M., Leaman, D., Jensen, R., Louis, J. M., Maruyama, T., Bewley, C. A., Bowdish, K., Clore, G. M., Dawson, P. E., Frederickson, S., et al. Antibody elicited against the gp41 N-heptad repeat (NHR) coiled-coil can neutralize HIV-1 with modest potency but non-neutralizing antibodies also bind to NHR mimetics Virology  2008 377:170-183  DOI:10.1016/j.virol.2008.04.005  PMID:18499210  PMCID:PMC2493441
  • Huang, C. C., Lam, S. N., Acharya, P., Tang, M., Xiang, S. H., Hussan, S. S. U., Stanfield, R. L., Robinson, J., Sodroski, J., Wilson, I. A., Wyatt, R., Bewley, C. A., et al. Structures of the ccr5 n terminus and of a tyrosine-sulfated antibody with hiv-1 gp120 and cd4 Science  2007 317:1930-1934  DOI:10.1126/science.1145373  PMID:17901336  PMCID:PMC2278242
  • Nicholas, G. M., Eckman, L. L., Ray, S., Hughes, R. O., Pfefferkorn, J. A., Barluenga, S., Nicolaou, K. C., Bewley, C. A. Bromotyrosine-derived natural and synthetic products as inhibitors of mycothiol-S-conjugate amidase Bioorganic & Medicinal Chemistry Letters  2002 12:2487-2490  DOI:10.1016/s0960-894x(02)00385-2  PMID:12161164