recent publications

• academic article

  • Roth, D. M., Hutt, D. M., Tong, J., Bouchecareilh, M., Wang, N., Seeley, T., Dekkers, J. F., Beekman, J. M., Garza, D., Drew, L., Masliah, E., Morimoto, R. I., et al. Modulation of the maladaptive stress response to manage diseases of protein folding PLoS Biology  2014 12  DOI:10.1371/journal.pbio.1001998  PMID:25406061  PMCID:PMC4236052
  • Ryno, L. M., Genereux, J. C., Naito, T., Morimoto, R. I., Powers, E. T., Shoulders, M. D., Wiseman, R. L. Characterizing the altered cellular proteome induced by the stress-independent activation of heat shock factor 1 ACS Chemical Biology  2014 9:1273-1283  DOI:10.1021/cb500062n  PMID:24689980  PMCID:PMC4076015
  • Balch, W. E., Sznajder, J. I., Budinger, S., Finley, D., Laposky, A. D., Cuervo, A. M., Benjamin, I. J., Barreiro, E., Morimoto, R. I., Postow, L., Weissman, A. M., Gail, D., et al. Malfolded protein structure and proteostasis in lung diseases American Journal of Respiratory and Critical Care Medicine  2014 189:96-103  DOI:10.1164/rccm.201306-1164WS  PMID:24033344  PMCID:PMC3919126
  • Calamini, B., Silva, M. C., Madoux, F., Hutt, D. M., Khanna, S., Chalfant, M. A., Saldanha, S. A., Hodder, P., Tait, B. D., Garza, D., Balch, W. E., Morimoto, R. I. Small-molecule proteostasis regulators for protein conformational diseases Nature Chemical Biology  2012 8:185-196  DOI:10.1038/nchembio.763  PMID:22198733  PMCID:PMC3262058
  • Powers, E. T., Morimoto, R. I., Dillin, A., Kelly, J. W., Balch, W. E. Biological and chemical approaches to diseases of proteostasis deficiency Annual Review of Biochemistry  2009 78:959-991  DOI:10.1146/annurev.biochem.052308.114844  PMID:19298183
  • Balch, W. E., Morimoto, R. I., Dillin, A., Kelly, J. W. Adapting proteostasis for disease intervention Science  2008 319:916-919  DOI:10.1126/science.1141448  PMID:18276881