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Cortistatin a is a high-affinity ligand of protein kinases rock, cdk8, and cdk11

Academic Article
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Overview

authors

  • Cee, V. J.
  • Chen, D. Y. K.
  • Lee, M. R.
  • Nicolaou, K.C.

publication date

  • 2009

journal

  • Angewandte Chemie-International Edition  Journal

subject areas

  • Animals
  • Binding Sites
  • Cell Line
  • Computer Simulation
  • Crystallography, X-Ray
  • Cyclin-Dependent Kinase 8
  • Cyclin-Dependent Kinases
  • High-Throughput Screening Assays
  • Humans
  • Isoquinolines
  • Ligands
  • Polycyclic Compounds
  • Porifera
  • Protein Structure, Tertiary
  • rho-Associated Kinases
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Research

keywords

  • CDK
  • ROCK
  • angiogenesis
  • cortistatin A
  • kinases
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Identity

International Standard Serial Number (ISSN)

  • 1433-7851

Digital Object Identifier (DOI)

  • 10.1002/anie.200904778

PubMed ID

  • 19844931
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Additional Document Info

start page

  • 8952

end page

  • 8957

volume

  • 48

issue

  • 47

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