On the role of DNA synthesis in avian tumor virus infection

Academic Article

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Overview

authors

• Duesberg, P. H.
• Vogt, Peter K.

publication date

• 1969

journal

• Proceedings of the National Academy of Sciences of the United States of America  Journal

abstract

• Preinfection of chick embryo fibroblasts with an avian tumor virus does not eliminate the requirement of early DNA synthesis for other avian tumor viruses superinfecting the same cells several days after the primary inoculum. The function served by the early DNA in avian tumor virus infection either fails to persist into late infection or is genetically specific for each viral type.

subject areas

• Animals
• Avian Leukosis Virus
• Avian Sarcoma Viruses
• Centrifugation, Density Gradient
• Chick Embryo
• Cytarabine
• Cytopathogenic Effect, Viral
• DNA, Viral
• Depression, Chemical
• Fibroblasts
• Satellite Viruses
• Thymidine
• Virus Replication

Identity

PubMed Central ID

• PMC223325

International Standard Serial Number (ISSN)

• 0027-8424

Digital Object Identifier (DOI)

• 10.1073/pnas.64.3.939

PubMed ID

• 4313334

Additional Document Info

start page

• 939

end page

• 946

volume

• 64

issue

• 3