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High resolution solution structure of a DNA duplex alkylated by the antitumor agent duocarmycin SA

Academic Article
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Overview

related to degree

  • Smith, Jarrod Anson, Ph.D. in Biology, Scripps Research 1992 - 1999

authors

  • Eis, P. S.
  • Smith, Jarrod Anson
  • Rydzewski, J. M.
  • Case, David A.
  • Boger, Dale
  • Chazin, Walter J.

publication date

  • September 1997

journal

  • Journal of Molecular Biology  Journal

subject areas

  • Antineoplastic Agents, Alkylating
  • Binding Sites
  • DNA
  • Indoles
  • Ligands
  • Magnetic Resonance Spectroscopy
  • Models, Molecular
  • Nucleic Acid Conformation
  • Pyrroles
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Research

keywords

  • DNA alkylation
  • DNA minor groove binding
  • NMR
  • duocarmycin
  • shape-dependent catalysis
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Identity

International Standard Serial Number (ISSN)

  • 0022-2836

Digital Object Identifier (DOI)

  • 10.1006/jmbi.1997.1223

PubMed ID

  • 9299351
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Additional Document Info

start page

  • 237

end page

  • 252

volume

  • 272

issue

  • 2

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