recent publications

• academic article

  • Kang, Y., Zhou, X. E., Gao, X., He, Y., Liu, W., Ishchenko, A., Barty, A., Sathish, D., Yefanov, O., Han, G. W., Xu, Q., de Waal, P. W., et al. Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser Nature  2015 523:561-567  DOI:10.1038/nature14656  PMID:26200343  PMCID:PMC4521999
  • Park, D. J., Dudas, G., Wohl, S., Goba, A., Whitmer, S. L. M., Andersen, K. G., Sealfon, R. S., Ladner, J. T., Kugelman, J. R., Matranga, C. B., Winnicki, S. M., Qu, J., et al. Ebola virus epidemiology, transmission, and evolution during seven months in Sierra Leone Cell  2015 161:1516-1526  DOI:10.1016/j.cell.2015.06.007  PMID:26091036  PMCID:PMC4503805
  • Liu, T., Zhang, Y., Liu, Y., Wang, Y., Jia, H., Kang, M., Luo, X., Caballero, D., Gonzalez, J., Sherwood, L., Nunez, V., Wang, D., et al. Functional human antibody CDR fusions as long-acting therapeutic endocrine agonists Proceedings of the National Academy of Sciences of the United States of America  2015 112:1356-1361  DOI:10.1073/pnas.1423668112  PMID:25605877  PMCID:PMC4321239
  • Nogly, P., James, D., Wang, D., White, T. A., Zatsepin, N., Shilova, A., Nelson, G., Liu, H., Johansson, L., Heymann, M., Jaeger, K., Metz, M., et al. Lipidic cubic phase serial millisecond crystallography using synchrotron radiation IUCrJ  2015 2:168-176  DOI:10.1107/s2052252514026487  PMID:25866654
  • Kim, M. S., Ma, J. S. Y., Yun, H., Cao, Y., Kim, J. Y., Chi, V., Wang, D., Woods, A., Sherwood, L., Caballero, D., Gonzalez, J., Schultz, P. G., et al. Redirection of genetically engineered CAR-T cells using bifunctional small molecules Journal of the American Chemical Society  2015 137:2832-2835  DOI:10.1021/jacs.5b00106  PMID:25692571
  • Fenalti, G., Zatsepin, N. A., Betti, C., Giguere, P., Han, G. W., Ishchenko, A., Liu, W., Guillemyn, K., Zhang, H., James, D., Wang, D., Weierstall, U., et al. Structural basis for bifunctional peptide recognition at human delta-opioid receptor Nature Structural & Molecular Biology  2015 22:265-268  DOI:10.1038/nsmb.2965  PMID:25686086  PMCID:PMC4351130
  • Zhang, Y., Goswami, D., Wang, D., Wang, T. S. A., Sen, S., Magliery, T. J., Griffin, P. R., Wang, F., Schultz, P. G. An antibody with a variable-region coiled-coil "knob" domain Angewandte Chemie-International Edition  2014 53:132-135  DOI:10.1002/anie.201307939  PMID:24254636  PMCID:PMC3926434
  • Han, C., Song, Y., Xiao, H., Wang, D., Franc, N. C., Jan, L. Y., Jan, Y. N. Epidermal cells are the primary phagocytes in the fragmentation and clearance of degenerating dendrites in Drosophila Neuron  2014 81:544-560  DOI:10.1016/j.neuron.2013.11.021  PMID:24412417  PMCID:PMC3995171
  • Weierstall, U., James, D., Wang, C., White, T. A., Wang, D., Liu, W., Spence, J. C. H., Doak, R. B., Nelson, G., Fromme, P., Fromme, R., Grotjohann, I., et al. Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography Nature Communications  2014 5:3309  DOI:10.1038/ncomms4309  PMID:24525480  PMCID:PMC4061911
  • Zong, N., Ping, P., Lau, E., Choi, H. J. H., Ng, D. C. M., Meyer, D., Fang, C., Li, H., Wang, D., Zelaya, I. M., Yates III, J. R., Lam, M. P. Y. Lysine ubiquitination and acetylation of human cardiac 20S proteasomes Proteomics Clinical Applications  2014 8:590-594  DOI:10.1002/prca.201400029  PMID:24957502
  • Wang, L., Limbo, O., Fei, J., Chen, L., Kim, B., Luo, J., Chong, J., Conaway, R. C., Conaway, J. W., Ranish, J. A., Kadonaga, J. T., Russell, P., et al. Regulation of the Rhp26(ERCC6/CSB) chromatin remodeler by a novel conserved leucine latch motif Proceedings of the National Academy of Sciences of the United States of America  2014 111:18566-18571  DOI:10.1073/pnas.1420227112  PMID:25512493  PMCID:PMC4284531
  • Liu, W., Wacker, D., Gati, C., Han, G. W., James, D., Wang, D., Nelson, G., Weierstall, U., Katritch, V., Barty, A., Zatsepin, N. A., Li, D., et al. Serial femtosecond crystallography of G protein-coupled receptors Science  2013 342:1521-1524  DOI:10.1126/science.1244142  PMID:24357322  PMCID:PMC3902108
  • Lu, H., Wang, D., Kazane, S., Javahishvili, T., Tian, F., Song, F., Sellers, A., Barnett, B., Schultz, P. G. Site-specific antibody-polymer conjugates for siRNA delivery Journal of the American Chemical Society  2013 135:13885-13891  DOI:10.1021/ja4059525  PMID:23924037  PMCID:PMC3955097
  • Wang, D., Nasto, L. A., Roughley, P., Leme, A. S., Houghton, A. M., Usas, A., Sowa, G., Lee, J., Niedernhofer, L., Shapiro, S., Kang, J., Vo, N. Spine degeneration in a murine model of chronic human tobacco smokers Osteoarthritis and Cartilage  2012 20:896-905  DOI:10.1016/j.joca.2012.04.010  PMID:22531458  PMCID:PMC3389285
  • Wang, D., Vo, N. V., Sowa, G. A., Hartman, R. A., Ngo, K., Choe, S. R., Witt, W. T., Dong, Q., Lee, J. Y., Niedernhofer, L. J., Kang, J. D. Bupivacaine decreases cell viability and matrix protein synthesis in an intervertebral disc organ model system Spine Journal  2011 11:139-146  DOI:10.1016/j.spinee.2010.11.017  PMID:21296298  PMCID:PMC3056334
  • Vo, N., Seo, H. Y., Robinson, A., Sowa, G., Bentley, D., Taylor, L., Studer, R., Usas, A., Huard, J., Alber, S., Watkins, S. C., Lee, J., et al. Accelerated aging of intervertebral discs in a mouse model of progeria Journal of Orthopaedic Research  2010 28:1600-1607  DOI:10.1002/jor.21153  PMID:20973062  PMCID:PMC3477798
  • Johnson, A. D., Gong, Y., Wang, D., Langaee, T. Y., Shin, J., Cooper-DeHoff, R. M., Schork, N. J., Binkley, P., Pepine, C. J., Johnson, J. A., Sadee, W. Promoter polymorphisms in ace (angiotensin i-converting enzyme) associated with clinical outcomes in hypertension Clinical Pharmacology & Therapeutics  2009 85:36-44  DOI:10.1038/clpt.2008.194  PMID:18946466  PMCID:PMC2709290
  • Wilkinson, M. D., Senger, M., Kawas, E., Bruskiewich, R., Gouzy, J., Noirot, C., Bardou, P., Ng, A., Haase, D., Saiz, E. D., Wang, D., Gibbons, F., et al. Interoperability with Moby 1.0: it's better than sharing your toothbrush Briefings in Bioinformatics  2008 9:220-231  DOI:10.1093/bib/bbn003  PMID:18238804
  • Yeamans, C., Wang, D., Paz-Priel, I., Torbett, B. E., Tenen, D. G., Friedman, A. D. C/EBPalpha binds and activates the PU.1 distal enhancer to induce monocyte lineage commitment Blood  2007 110:3136-3142  DOI:10.1182/blood-2007-03-080291  PMID:17671233  PMCID:PMC2200910
  • Beitelshees, A. L., Gong, Y., Wang, D., Schork, N. J., Cooper-DeHoff, R. M., Langaee, T. Y., Shriver, M. D., Sadee, W., Knot, H. J., Pepine, C. J., Johnson, J. A., Investigators, Invest Kcnmb1 genotype influences response to verapamil sir and adverse outcomes in the international verapamil sr/trandolapril study (invest) Pharmacogenetics and Genomics  2007 17:719-729  DOI:10.1097/FPC.0b013e32810f2e3c  PMID:17700361  PMCID:PMC2713584
  • Takagi, Y., Masuda, C. A., Chang, W. H., Komori, H., Wang, D., Hunter, T., Joazeiro, C. A. P., Kornberg, R. D. Ubiquitin ligase activity of tfiih and the transcriptional response to DNA damage Molecular Cell  2005 18:237-243  DOI:10.1016/j.molcel.2005.03.007  PMID:15837426
  • Brandenberger, R., Schmidt, A., Linton, J., Wang, D., Backus, C., Denda, S., Muller, U., Reichardt, L. F. Identification and characterization of a novel extracellular matrix protein nephronectin that is associated with integrin alpha 8 beta 1 in the embryonic kidney Journal of Cell Biology  2001 154:447-458  DOI:10.1083/jcb.200103069  PMID:11470831  PMCID:PMC2150762
  • Xu, B., Gottschalk, W., Chow, A., Wilson, R. I., Schnell, E., Zang, K., Wang, D., Nicoll, R. A., Lu, B., Reichardt, L. F. The role of brain-derived neurotrophic factor receptors in the mature hippocampus: modulation of long-term potentiation through a presynaptic mechanism involving TrkB Journal of Neuroscience  2000 20:6888-6897  PMID:10995833  PMCID:PMC2711895
  • Lin, S. W., Kochendoerfer, G. G., Carroll, K. S., Wang, D., Mathies, R. A., Sakmar, T. P. Mechanisms of spectral tuning in blue cone visual pigments. Visible and raman spectroscopy of blue-shifted rhodopsin mutants Journal of Biological Chemistry  1998 273:24583-24591  DOI:10.1074/jbc.273.38.24583  PMID:9733753
  • Schroder, U., Cider, L., Schoon, N. H., Baltanas, M. A., Blackmond, D. G., Datye, A. K., Conner, W. C., Hightower, J. W., Guo, X. X., Wang, D. An in-situ radioactive-tracer technique for studying adsorption-desorption dynamics on a working catalyst Studies in Surface Science and Catalysis  1993 75:643-657
  • Marinelli, Tblw, Vleeming, J. H., Ponec, V., Wang, D., Blackmond, D. G., Arntz, D., Jannes, G., Kunimori, K., Rochester, C. H. Reactions of multifunctional organic-compounds - hydrogenation of acrolein on modified pt-catalysts Studies in Surface Science and Catalysis  1993 75:1211-1222
  • Lin, S. D., Vannice, M. A., Herrmann, J. M., Wang, D., Apestequia, C., Duprez, D., Figueras, F., Conner, W. C., Kiperman, S. L., Hall, W. K., Blackmond, D. G., Grunert, W., et al. Toluene hydrogenation over supported platinum catalysts Studies in Surface Science and Catalysis  1993 75:861-874