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Effect of abciximab on the pattern of reperfusion in patients with acute myocardial infarction treated with primary angioplasty

Academic Article
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Overview

authors

  • Brener, S. J.
  • Barr, L. A.
  • Burchenal, J. E. B.
  • Wolski, K. E.
  • Effron, M. B.
  • Topol, Eric
  • Investigators, Rapport

publication date

  • September 1999

journal

  • American Journal of Cardiology  Journal

abstract

  • We investigated the effect of platelet fibrinogen receptor blockade on infarct size after primary angioplasty. Abciximab significantly reduced the time-to-peak creatine kinase without affecting enzymatic infarct size, suggesting a beneficial effect on the pattern and speed of reperfusion.

subject areas

  • Aged
  • Angioplasty, Balloon, Coronary
  • Antibodies, Monoclonal
  • Coronary Angiography
  • Creatine Kinase
  • Dose-Response Relationship, Drug
  • Drug Administration Schedule
  • Female
  • Humans
  • Immunoglobulin Fab Fragments
  • Infusions, Intravenous
  • Male
  • Middle Aged
  • Myocardial Infarction
  • Myocardial Reperfusion Injury
  • Platelet Aggregation Inhibitors
  • Recurrence
  • Retreatment
  • Treatment Outcome
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Identity

International Standard Serial Number (ISSN)

  • 0002-9149

Digital Object Identifier (DOI)

  • 10.1016/s0002-9149(99)00421-x

PubMed ID

  • 10498145
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Additional Document Info

start page

  • 728

end page

  • 730

volume

  • 84

issue

  • 6

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