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Analytical Chemistry

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articles

  • Enhanced in-Source Fragmentation Annotation Enables Novel Data Independent Acquisition and Autonomous METLIN Molecular Identification.  92:6051-6059. 2020
  • EThcD and 213 nm UVPD for top-down analysis of bovine seminal plasma proteoforms on electrophoretic and chromatographic time frames.  92:2979-2987. 2020
  • Improving proteomics data reproducibility with a dual-search strategy.  92:1697-1701. 2020
  • Comparative Analysis of Cleavage Specificities of Immobilized Porcine Pepsin and Nepenthesin II under Hydrogen/Deuterium Exchange Conditions.  92:11018-11028. 2020
  • PASS-DIA: A Data-Independent Acquisition Approach for Discovery Studies.  92:14466-14475. 2020
  • Autonomous METLIN-guided in-source fragment annotation for untargeted metabolomics.  91:3246-3253. 2019
  • Residue-specific conformational heterogeneity of proline-rich sequences uncovered via infrared spectroscopy.  90:14355-14362. 2018
  • Reply to comment on METLIN: A technology platform for identifying knowns and unknowns.  90:13128-13129. 2018
  • Epi-detected hyperspectral stimulated raman scattering microscopy for label-free molecular subtyping of glioblastomas.  90:10249-10255. 2018
  • Autonomous multimodal metabolomics data integration for comprehensive pathway analysis and systems biology.  90:8396-8403. 2018
  • Faster protocol for endogenous fatty acid esters of hydroxy fatty acid (FAHFA) measurements.  90:5358-5365. 2018
  • METLIN: A technology platform for identifying knowns and unknowns.  90:3156-3164. 2018
  • Correlative light-electron microscopy of lipid-encapsulated Fluorescent nanodiamonds for nanometric localization of cell surface antigens.  90:1566-1571. 2018
  • Annotation: A computational solution for streamlining metabolomics analysis.  90:480-489. 2018
  • Integrated, continuous emulsion creamer.  89:13227-13234. 2017
  • Exposome-scale investigations guided by global metabolomics, pathway analysis, and cognitive computing.  89:11505-11513. 2017
  • Morphology-driven control of metabolite selectivity using nanostructure-initiator mass spectrometry.  89:6521-6526. 2017
  • Evaluation of p-(C-13,N-15-cyano)phenylalanine as an extended time scale 2D IR probe of proteins.  89:5254-5260. 2017
  • Data streaming for metabolomics: accelerating data processing and analysis from days to minutes.  89:1254-1259. 2017
  • Aqueous two-phase system rehydration of antibody-polymer microarrays enables convenient compartmentalized multiplex immunoassays.  88:11328-11334. 2016
  • Smartphone analytics: mobilizing the lab into the cloud for omicscale analyses.  88:9753-9758. 2016
  • Profiling reactive metabolites via chemical trapping and targeted mass spectrometry.  88:6658-6661. 2016
  • Site-specific characterization of cytochrome P450cam conformations by infrared spectroscopy.  88:6598-6606. 2016
  • Two-site evaluation of the repeatability and precision of an automated dual-column hydrogen/deuterium exchange mass spectrometry platform.  88:6607-6614. 2016
  • Improved identification and analysis of small open reading frame encoded polypeptides.  88:3967-3975. 2016
  • Supramolecular affinity chromatography for methylation-targeted proteomics.  88:3697-3703. 2016
  • hvSABR: photochemical dose-response bead screening in droplets.  88:2904-2911. 2016
  • Discovery in droplets.  88:339. 2016
  • Extracting accurate precursor information for tandem mass spectra by raw converter.  87:11361-11367. 2015
  • Temperature Dependence of CN and SCN IR absorptions facilitates their interpretation and use as probes of proteins.  87:11561-11567. 2015
  • Thermal degradation of small molecules: a global metabolomic investigation.  87:10935-10941. 2015
  • Triomics analysis of imatinib-treated myeloma cells connects kinase inhibition to RNA processing and decreased lipid biosynthesis.  87:10995-11006. 2015
  • Online analysis of single cyanobacteria and algae cells under nitrogen-limited conditions using aerosol time-of-flight mass spectrometry.  87:8039-8046. 2015
  • Simultaneous quantification of methylated cytidine and adenosine in cellular and tissue RNA by Nano-Flow liquid chromatography-tandem mass spectrometry coupled with the stable isotope-dilution method.  87:7653-7659. 2015
  • When good intentions go awry: modification of a recombinant monoclonal antibody in chemically Defined Cell Culture by Xylosone, an Oxidative Product of Ascorbic Acid.  87:7529-7534. 2015
  • Efficient mapping of sulfated glycotopes by negative ion mode nanoLC-MS/MS-based sulfoglycomic analysis of permethylated glycans.  87:6380-6388. 2015
  • Differential isotopic enrichment to facilitate characterization of asymmetric multimeric proteins using hydrogen/deuterium exchange mass spectrometry.  87:4015-4022. 2015
  • Autonomous metabolomics for rapid metabolite identification in global profiling.  87:884-891. 2015
  • Bioinformatics: the next frontier of metabolomics.  87:147-156. 2015
  • Sheathless capillary electrophoresis-tandem mass spectrometry for top-down characterization of Pyrococcus furiosus proteins on a proteome scale.  86:11006-11012. 2014
  • isoMETLIN: a database for isotope-based metabolomics.  86:9358-9361. 2014
  • Discovery of a chemical modification by citric acid in a recombinant monoclonal antibody.  86:8932-8936. 2014
  • Interactive XCMS Online: simplifying advanced metabolomic data processing and subsequent statistical analyses.  86:6931-6939. 2014
  • Rapid enumeration of phage in monodisperse emulsions.  86:5642-5648. 2014
  • Discovery and characterization of a photo-oxidative histidine-histidine cross-link in IgG1 antibody utilizing (18)O-labeling and mass spectrometry.  86:4940-4948. 2014
  • Microfluidic bead suspension hopper.  86:5039-5044. 2014
  • Label-free direct visual analysis of hydrolytic enzyme activity using aqueous two-phase system droplet phase transitions.  86:4052-4057. 2014
  • Phosphoproteomics.  86:1313. 2014
  • Arginine modifications by methylglyoxal: discovery in a recombinant monoclonal antibody and contribution to acidic species.  85:11401-11409. 2013
  • Quantitative proteomics.  85:8881. 2013
  • BAD-lectins: boronic acid-decorated lectins with enhanced binding affinity for the selective enrichment of glycoproteins.  85:8268-8276. 2013
  • Preprogrammed, parallel on-chip immunoassay using system-level capillarity control.  85:6902-6907. 2013
  • Toward 'omic scale metabolite profiling: a dual separation-mass spectrometry approach for coverage of lipid and central carbon metabolism.  85:6876-6884. 2013
  • Discovery of undefined protein cross-linking chemistry: a comprehensive methodology utilizing 18-O-labeling and mass spectrometry.  85:5900-5908. 2013
  • Microfluidic amperometric sensor for analysis of nitric oxide in whole blood.  85:6066-6072. 2013
  • Microscale determination of aqueous two phase system binodals by droplet dehydration in oil.  85:5213-5218. 2013
  • Toward implementation of quorum sensing autoinducers as biomarkers for infectious disease states.  85:3355-62. 2013
  • Integrated proteomic analysis of major isoaspartyl-containing proteins in the urine of wild type and protein L-isoaspartate O-methyltransferase-deficient mice.  85:2423-2430. 2013
  • A view from above: Cloud plots to visualize global metabolomic data.  85:798-804. 2013
  • Top down proteomics.  85:6151. 2013
  • Improving the comprehensiveness and sensitivity of sheath less capillary electrophoresis-tandem mass spectrometry for proteomic analysis.  84:8505-8513. 2012
  • XCMS Online: a web-based platform to process untargeted metabolomic data.  84:5035-5039. 2012
  • Constant flow-driven microfluidic oscillator for different duty cycles.  84:1152-1156. 2012
  • Protein isoaspartate methyltransferase-mediated 18-O-labeling of isoaspartic acid for mass spectrometry analysis.  84:1056-1062. 2012
  • Iron oxide nanomatrix facilitating metal ionization in matrix-assisted laser desorption/ionization mass spectrometry.  83:9337-9343. 2011
  • Viral Quantitative Capillary Electrophoresis for Counting Intact Viruses.  83:5431-5435. 2011
  • Expanding coverage of the metabolome for global metabolite profiling.  83:2152-2161. 2011
  • Characterization of differences between blood sample matrices in untargeted metabolomics.  83:1040-1047. 2011
  • metaXCMS: second-order analysis of untargeted metabolomics data.  83:696-700. 2011
  • Nanostructure-initiator mass spectrometry metabolite analysis and imaging.  83:2-7. 2011
  • Multiplexed spectral signature detection for microfluidic color-coded bioparticle flow.  82:9506-9512. 2010
  • Analysis of isoaspartic acid by selective proteolysis with Asp-N and electron transfer dissociation mass spectrometry.  82:7485-7491. 2010
  • Native capillary isoelectric focusing for the separation of protein complex isoforms and subcomplexes.  82:6643-6651. 2010
  • Quantitation of the ribosomal protein autoregulatory network using mass spectrometry.  82:5038-5045. 2010
  • Combined immunocapture and laser desorption/ionization mass spectrometry on porous silicon.  82:4201-4208. 2010
  • Patterned electrode-based amperometric gas sensor for direct nitric oxide detection within microfluidic devices.  82:3300-3305. 2010
  • Fabrication of two-layered channel system with embedded electrodes to measure resistance across epithelial and endothelial barriers.  82:2505-2511. 2010
  • Development of an aptamer beacon for detection of interferon-gamma.  82:1851-1857. 2010
  • Dynamics of the beta(2)-adrenergic g-protein coupled receptor revealed by hydrogen-deuterium exchange.  82:1100-1108. 2010
  • Incorporation of the fluorescent ribonucleotide analogue tCTP by T7 RNA polymerase.  82:1082-1089. 2010
  • Nonlinear optical imaging of integral membrane protein crystals in lipidic mesophases.  82:491-497. 2010
  • Detection of carbohydrates and steroids by cation-enhanced nanostructure-initiator mass spectrometry (NIMS) for biofluid analysis and tissue imaging.  82:121-128. 2010
  • Chemical methods for the detection of protein N-homocysteinylation via selective reactions with aldehydes.  81:9065-9071. 2009
  • Fabrication of oriented antibody-conjugated magnetic nanoprobes and their immunoaffinity application.  81:8774-8782. 2009
  • High density labeling of polymerase chain reaction products with the fluorescent base analogue tCo.  81:9079-9085. 2009
  • Variability analysis of human plasma and cerebral spinal fluid reveals statistical significance of changes in mass spectrometry-based metabolomics data.  81:8538-8544. 2009
  • Iron oxide/gold core/shell nanoparticles for ultrasensitive detection of carbohydrate-protein interactions.  81:7750-7756. 2009
  • High-resolution temperature-concentration diagram of α-synuclein conformation obtained from a single Förster resonance energy transfer image in a microfluidic device.  81:6929-6935. 2009
  • Measurement of monovalent and polyvalent carbohydrate-lectin binding by back-scattering interferometry.  81:4889-4897. 2009
  • Multiplex charge-transfer interactions between quantum dots and peptide-bridged ruthenium complexes.  81:4831-4839. 2009
  • Hard top soft bottom microfluidic devices for cell culture and chemical analysis.  81:3714-3722. 2009
  • Nanostructure initiator mass spectrometry: Tissue imaging and direct biofluid analysis.  81:2969-2975. 2009
  • Charge prediction machine: tool for inferring precursor charge states of electron transfer dissociation tandem mass spectra.  81:1996-2003. 2009
  • Gas chromatographic separation of isotopic molecules using a cavitand-impregnated ionic liquid stationary phase.  81:1244-1254. 2009
  • Quantitative ESI-TOF analysis of macromolecular assembly kinetics.  80:9379-9386. 2008
  • Comparisons of mass spectrometry compatible surfactants for global analysis of the mammalian brain proteome.  80:8694-8701. 2008
  • Multidimensional lc separations in shotgun proteomics.  80:7187-7193. 2008
  • Multiplexed immunoassay: quantitation and profiling of serum biomarkers using magnetic nanoprobes and MALDI-TOF MS.  80:6159-6167. 2008
  • XCMS2: Processing tandem mass spectrometry data for metabolite identification and structural characterization.  80:6382-6389. 2008
  • Electromechanical properties of pressure-actuated poly(dimethylsiloxane) microfluidic push-down valves.  80:6110-6113. 2008
  • Biarsenical-tetracysteine motif as a fluorescent tag for detection in capillary electrophoresis.  80:5358-5366. 2008
  • Desorption ionization of biomolecules on metals.  80:5203-5210. 2008
  • Quantitative analysis of isotope distributions in proteomic mass spectrometry using least-squares Fourier transform convolution.  80:4906-4917. 2008
  • Chemo-enzymatic detection of protein isoaspartate using protein Isoaspartate methyltransferase and hydrazine trapping.  80:3882-3889. 2008
  • Improving protein identification sensitivity by combining MS and MS/MS information for shotgun proteomics using LTQ-Orbitrap high mass accuracy data.  80:2018-2025. 2008
  • Partial acetylation of lysine residues improves intraprotein cross-linking.  80:951-960. 2008
  • Multiple ionization mass spectrometry strategy used to reveal the complexity of metabolomics.  80:421-429. 2008
  • RCADiA: simple automation platform for comparative multidimensional protein identification technology.  79:6410-6418. 2007
  • Optimizing TiO2-based phosphopeptide enrichment for automated multidimensional liquid chromatography coupled to tandem mass spectrometry.  79:4666-4673. 2007
  • Shotgun analysis of integral membrane proteins facilitated by elevated temperature.  79:4613-4620. 2007
  • Anion and cation mixed-bed ion exchange for enhanced multidimensional separations of peptides and phosphopeptides.  79:3623-3634. 2007
  • Functionalized magnetic nanoparticles for small-molecule isolation, identification, and quantification.  79:3401-3408. 2007
  • Leakage-free bonding of porous membranes into layered microfluidic array systems.  79:3504-3508. 2007
  • Relative quantification of stable isotope labeled peptides using a linear ion trap-Orbitrap hybrid mass spectrometer.  79:3056-3064. 2007
  • Automatic validation of phosphopeptide identifications from tandem mass spectra.  79:1301-1310. 2007
  • Gravity-driven microfluidic particle sorting device with hydrodynamic separation amplification.  79:1369-1376. 2007
  • Characterization and resolution of evaporation-mediated osmolality shifts that constrain microfluidic cell culture in poly(dimethylsiloxane) devices.  79:1126-1134. 2007
  • Microfluidic serial dilution circuit.  78:7522-7527. 2006
  • Automated ultra-high-pressure multidimensional protein identification technology (UHP-MudPIT) for improved peptide identification of proteomic samples.  78:5109-5118. 2006
  • Nonlinear data alignment for uplc-ms and hplc-ms based metabolomics: Quantitative analysis of endogenous and exogenous metabolites in human serum.  78:3289-3295. 2006
  • Application of capture-recapture models to estimation of protein count in MudPIT experiments.  78:3203-3207. 2006
  • Cross-correlation algorithm for calculation of peptide molecular weight from tandem mass spectra.  78:1921-1929. 2006
  • Probing protein ligand interactions by automated hydrogen/deuterium exchange mass spectrometry.  78:1005-1014. 2006
  • Solvent-dependent metabolite distribution, clustering, and protein extraction for serum profiling with mass spectrometry.  78:743-752. 2006
  • Xcms: Processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching, and identification.  78:779-787. 2006
  • Performance of a linear ion trap-Orbitrap hybrid for peptide analysis.  78:493-500. 2006
  • Central limit theorem as an approximation for intensity-based scoring function.  78:89-95. 2006
  • Surfactant-enhanced desorption/ionization on silicon mass spectrometry.  78:272-278. 2006
  • Measurement of the isotope enrichment of stable isotope-labeled proteins using high-resolution mass spectra of peptides.  77:7646-7653. 2005
  • Combined top-down and bottom-up mass spectrometric approach to characterization of biomarkers for renal disease.  77:7163-7171. 2005
  • Nanoprobe-based affinity mass spectrometry for selected protein profiling in human plasma.  77:5990-5997. 2005
  • Computer-controlled microcirculatory support system for endothelial cell culture and shearing.  77:3993-3999. 2005
  • Desorption/ionization on silicon nanowires.  77:1641-1646. 2005
  • Sparsely cross-linked "nanogel" matrixes as fluid, mechanically stabilized polymer networks for high-throughput microchannel DNA sequencing.  76:5249-5256. 2004
  • Metabolic labeling of mammalian organisms with stable isotopes for quantitative proteomic analysis.  76:4951-4959. 2004
  • High sensitivity and analyte capture with desorption/ionization mass spectrometry on silylated porous silicon.  76:4484-4489. 2004
  • A model for random sampling and estimation of relative protein abundance in shotgun proteomics.  76:4193-4201. 2004
  • Impact of ion trap tandem mass spectra variability on the identification of peptides.  76:2928-2937. 2004
  • Statistical models for protein validation using tandem mass spectral data and protein amino acid sequence databases.  76:1664-1671. 2004
  • Influence of basic residue content on fragment ion peak intensities in low-energy collision-induced dissociation spectra of peptides.  76:1243-1248. 2004
  • A correlation algorithm for the automated quantitative analysis of shotgun proteomics data.  75:6912-6921. 2003
  • GutenTag: high-throughput sequence tagging via an empirically derived fragmentation model.  75:6415-6421. 2003
  • Integrated hydrogenated amorphous Si photodiode detector for microfluidic bioanalytical devices.  75:5300-5305. 2003
  • Quantitative analysis with desorption/ionization on silicon mass spectrometry using electrospray deposition.  75:5475-5479. 2003
  • Reproducibility of quantitative proteomic analyses of complex biological mixtures by multidimensional protein identification technology.  75:5054-5061. 2003
  • A hypergeometric probability model for protein identification and validation using tandem mass spectral data and protein sequence databases.  75:3792-3798. 2003
  • Combined electron capture and infrared multiphoton dissociation for multistage ms/ms in a fourier transform ion cyclotron resonance mass spectrometer.  75:3256-3262. 2003
  • Desorption/ionization on silicon time-of-flight/time-of-flight mass spectrometry.  75:2504-2506. 2003
  • Similarity among tandem mass spectra from proteomic experiments: detection, significance, and utility.  75:2470-2477. 2003
  • Cleavage N-terminal to proline: analysis of a database of peptide tandem mass spectra.  75:1963-1971. 2003
  • Passively driven integrated microfluidic system for separation of motile sperm.  75:1671-1675. 2003
  • Statistical characterization of ion trap tandem mass spectra from doubly charged tryptic peptides.  75:1155-1163. 2003
  • Effect of signal interference from dosing excipients on pharmacokinetic screening of drug candidates by liquid chromatography/mass spectrometry.  74:6305-6313. 2002
  • Probability-based validation of protein identifications using a modified SEQUEST algorithm.  74:5593-5599. 2002
  • Microchip bioprocessor for integrated nanovolume sample purification and DNA sequencing.  74:5092-5098. 2002
  • Automated affinity capture-release of biotin-containing conjugates using a lab-on-valve apparatus coupled to UV/visible and electrospray ionization mass spectrometry.  74:4702-4708. 2002
  • Processing complex mixtures of intact proteins for direct analysis by mass spectrometry.  74:2923-2929. 2002
  • Analysis of quantitative proteomic data generated via multidimensional protein identification technology.  74:1650-1657. 2002
  • Improvement in the apparent mass resolution of oligonucleotides by using 12C/14N-enriched samples.  74:226-231. 2002
  • An automated multidimensional protein identification technology for shotgun proteomics.  73:5683-5690. 2001
  • Porous silicon as a versatile platform for laser desorption/ionization mass spectrometry.  73:612-619. 2001
  • MS for identification of single nucleotide polymorphisms and MS/MS for discrimination of isomeric PCR products.  72:4033-4040. 2000
  • Equilibrium and kinetic measurements of muscarinic receptor antagonism on living cells using bead injection spectroscopy.  72:3109-3115. 2000
  • Turn geometry for minimizing band broadening in microfabricated capillary electrophoresis channels.  72:3030-3037. 2000
  • Amperometric detection of escherichia coli heat labile enterotoxin by redox diacetylenic vesicles on a sol-gel thin film electrode.  72:1611-1617. 2000
  • Automated identification of amino acid sequence variations in proteins by HPLC/microspray tandem mass spectrometry.  72:757-763. 2000
  • Detection of oxygen consumption of cultured adherent cells by bead injection spectroscopy.  71:5248-5252. 1999
  • Identification of proteins in complexes by solid phase microextraction multistep elution capillary electrophoresis tandem mass spectrometry.  71:2270-2278. 1999
  • Nanoelectrospray mass spectrometry and precursor ion monitoring for quantitative steroid analysis and attomole sensitivity.  71:2358-2363. 1999
  • Cellular applications of a sensitive and selective fiber optic nitric oxide biosensor based on a dye-labeled heme domain of soluble guanylate cyclase.  71:2071-2075. 1999
  • Hydrodynamics and mass transfer of the coaxial jet mixer in flow injection analysis.  71:2199-2204. 1999
  • From flow injection to bead injection.  71:257A-263A. 1999
  • A flow injection renewable surface technique for cell-based drug discovery functional assays.  71:1160-1166. 1999
  • Optimization of high-speed DNA sequencing on microfabricated capillary electrophoresis channels.  71:566-573. 1999
  • Method to compare collision-induced dissociation spectra of peptides: potential for library searching and subtractive analysis.  70:3557-3565. 1998
  • An automated maldi mass spectrometry approach for optimizing cyclosporin extraction and quantitation.  69:3767-3771. 1997
  • Direct analysis and identification of proteins in mixtures by LC/MS/MS and database searching at the low-femtomole level.  69:767-776. 1997
  • Mining genomes with MS.  68:534A-540A. 1996
  • Mixture analysis using a quadrupole mass filter quadrupole ion trap mass spectrometer.  68:659-667. 1996
  • Mining genomes: correlating tandem mass spectra of modified and unmodified peptides to sequences in nucleotide databases.  67:3202-3210. 1995
  • A coaxial jet mixer for rapid kinetic analysis in flow injection and flow injection cytometry.  67:2743-2749. 1995
  • Characterization of the complexity of small-molecule libraries by electrospray ionization mass spectrometry.  67:2906-2915. 1995
  • Method to correlate tandem mass spectra of modified peptides to amino acid sequences in the protein database.  67:1426-1436. 1995
  • Molecular-biology at atomic resolution. The structure of an insect virus and its functional implications.  61:1341A-1350A. 1989
  • Tandem quadrupole-Fourier transform mass spectrometry of oligopeptides.  57:2728-2733. 1985
  • Adaptation of oxygen flask method for ashing of cellulosic materials.  35:1558-1559. 1963
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Identity

International Standard Serial Number (ISSN)

  • 0003-2700

Electronic International Standard Serial Number (EISSN)

  • 1520-6882

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