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Intramolecular ion-pair prodrugs of zanamivir and guanidino-oseltamivir

Academic Article
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Overview

authors

  • Liu, K. C.
  • Lee, Pauline
  • Wang, S. Y.
  • Cheng, Y. S. E.
  • Fang, J. M.
  • Wong, Chi-Huey

publication date

  • August 2011

journal

  • Bioorganic & Medicinal Chemistry  Journal

subject areas

  • Administration, Oral
  • Antiviral Agents
  • Carbon Dioxide
  • Cell Line
  • Drug Evaluation, Preclinical
  • Enzyme Inhibitors
  • Esters
  • Guanidine
  • Humans
  • Hydrophobic and Hydrophilic Interactions
  • Influenza A virus
  • Influenza, Human
  • Ions
  • Molecular Structure
  • Naphthols
  • Neuraminidase
  • Oseltamivir
  • Prodrugs
  • Zanamivir
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Research

keywords

  • Influenza
  • Intramolecular ion-pair
  • Neuraminidase inhibitor
  • Prodrug
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Identity

International Standard Serial Number (ISSN)

  • 0968-0896

Digital Object Identifier (DOI)

  • 10.1016/j.bmc.2011.06.080

PubMed ID

  • 21778065
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Additional Document Info

start page

  • 4796

end page

  • 4802

volume

  • 19

issue

  • 16

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