recent publications
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academic article
- Hamilton-Williams, E. E., Rainbow, D. B., Cheung, J., Christensen, M., Lyons, P. A., Peterson, L. B., Steward, C. A., Sherman, L. A., Wicker, L. S. Fine mapping of type 1 diabetes regions Idd9.1 and Idd9.2 reveals genetic complexity Mammalian Genome 2013 24:358-375 DOI:10.1007/s00335-013-9466-y PMID:23934554 PMCID:PMC3824839
- Lin, X., Hamilton-Williams, E. E., Rainbow, D. B., Hunter, K. M., Dai, Y. D., Cheung, J., Peterson, L. B., Wicker, L. S., Sherman, L. A. Genetic interactions among Idd3, Idd5.1, Idd5.2, and Idd5.3 protective loci in the nonobese diabetic mouse model of type 1 diabetes Journal of Immunology 2013 190:3109-3120 DOI:10.4049/jimmunol.1203422 PMID:23427248 PMCID:PMC3608810
- Maine, C. J., Hamilton-Williams, E. E., Cheung, J., Stanford, S. M., Bottini, N., Wicker, L. S., Sherman, L. A. PTPN22 alters the development of regulatory T cells in the thymus Journal of Immunology 2012 188:5267-5275 DOI:10.4049/jimmunol.1200150 PMID:22539785 PMCID:PMC3358490
- Hamilton-Williams, E. E., Cheung, J., Rainbow, D. B., Hunter, K. M., Wicker, L. S., Sherman, L. A. Cellular mechanisms of restored β-cell tolerance mediated by protective alleles of Idd3 and Idd5 Diabetes 2012 61:166-174 DOI:10.2337/db11-0790 PMID:22106155 PMCID:PMC3237671
- Hamilton-Williams, E. E., Wong, S. B. J., Martinez, X., Rainbow, D. B., Hunter, K. M., Wicker, L. S., Sherman, L. A. Idd9.2 and Idd9.3 protective alleles function in CD4+ T-cells and nonlymphoid cells to prevent expansion of pathogenic islet-specific CD8+ T-cells Diabetes 2010 59:1478-1486 DOI:10.2337/db09-1801 PMID:20299469 PMCID:PMC2874709
- Hamilton-Williams, E. E., Martinez, X., Clark, J., Howlett, S., Hunter, K. M., Rainbow, D. B., Wen, L., Shlomchik, M. J., Katz, J. D., Beilhack, G. F., Wicker, L. S., Sherman, L. A. Expression of diabetes-associated genes by dendritic cells and CD4 T cells drives the loss of tolerance in nonobese diabetic mice Journal of Immunology 2009 183:1533-1541 DOI:10.4049/jimmunol.0900428 PMID:19592648 PMCID:PMC2733871
- Dai, Y. D., Marrero, I. G., Gros, P., Zaghouani, H., Wicker, L. S., Sercarz, E. E. Slc11a1 enhances the autoimmune diabetogenic T-cell response by altering processing and presentation of pancreatic islet antigens Diabetes 2009 58:156-164 DOI:10.2337/db07-1608 PMID:18984740 PMCID:PMC2606865
- Mattner, J., Savage, P. B., Leung, P., Oertelt, S. S., Wang, V., Trivedi, O., Scanlon, S. T., Pendem, K., Teyton, L., Hart, J., Ridgway, W. M., Wicker, L. S., et al. Liver autoimmunity triggered by microbial activation of natural killer T cells Cell Host & Microbe 2008 3:304-315 DOI:10.1016/j.chom.2008.03.009 PMID:18474357 PMCID:PMC2453520
- Hamilton-Williams, E. E., Martinez, X., Lyman, M., Hunter, K., Wicker, L. S., Sherman, L. A. The use of Idd congenic mice to identify checkpoints of peripheral tolerance to islet antigen Annals of the New York Academy of Sciences 2007 1103:118-127 DOI:10.1196/annals.1394.003 PMID:17376833
- Martinez, X., Kreuwel, H. T. C., Redmond, W. L., Trenney, R., Hunter, K., Rosen, H., Sarvetnick, N., Wicker, L. S., Sherman, L. A. CD8+ T cell tolerance in nonobese diabetic mice is restored by insulin-dependent diabetes resistance alleles Journal of Immunology 2005 175:1677-1685 PMID:16034108
- McAleer, M. A., Reifsnyder, P., Palmer, S. M., Prochazka, M., Love, J. M., Copeman, J. B., Powell, E. E., Rodrigues, N. R., Prins, J. B., Serreze, D. V., Delarato, N. H., Wicker, L. S., et al. Crosses of nod mice with the related non strain - a polygenic model for iddm Diabetes 1995 44:1186-1195 DOI:10.2337/diabetes.44.10.1186 PMID:7556956