recent publications

• academic article

  • Hamilton-Williams, E. E., Rainbow, D. B., Cheung, J., Christensen, M., Lyons, P. A., Peterson, L. B., Steward, C. A., Sherman, L. A., Wicker, L. S. Fine mapping of type 1 diabetes regions Idd9.1 and Idd9.2 reveals genetic complexity Mammalian Genome  2013 24:358-375  DOI:10.1007/s00335-013-9466-y  PMID:23934554  PMCID:PMC3824839
  • Lin, X., Hamilton-Williams, E. E., Rainbow, D. B., Hunter, K. M., Dai, Y. D., Cheung, J., Peterson, L. B., Wicker, L. S., Sherman, L. A. Genetic interactions among Idd3, Idd5.1, Idd5.2, and Idd5.3 protective loci in the nonobese diabetic mouse model of type 1 diabetes Journal of Immunology  2013 190:3109-3120  DOI:10.4049/jimmunol.1203422  PMID:23427248  PMCID:PMC3608810
  • Hamilton-Williams, E. E., Cheung, J., Rainbow, D. B., Hunter, K. M., Wicker, L. S., Sherman, L. A. Cellular mechanisms of restored β-cell tolerance mediated by protective alleles of Idd3 and Idd5 Diabetes  2012 61:166-174  DOI:10.2337/db11-0790  PMID:22106155  PMCID:PMC3237671
  • Maine, C. J., Hamilton-Williams, E. E., Cheung, J., Stanford, S. M., Bottini, N., Wicker, L. S., Sherman, L. A. PTPN22 alters the development of regulatory T cells in the thymus Journal of Immunology  2012 188:5267-5275  DOI:10.4049/jimmunol.1200150  PMID:22539785  PMCID:PMC3358490
  • Hamilton-Williams, E. E., Wong, S. B. J., Martinez, X., Rainbow, D. B., Hunter, K. M., Wicker, L. S., Sherman, L. A. Idd9.2 and Idd9.3 protective alleles function in CD4+ T-cells and nonlymphoid cells to prevent expansion of pathogenic islet-specific CD8+ T-cells Diabetes  2010 59:1478-1486  DOI:10.2337/db09-1801  PMID:20299469  PMCID:PMC2874709
  • Hamilton-Williams, E. E., Martinez, X., Clark, J., Howlett, S., Hunter, K. M., Rainbow, D. B., Wen, L., Shlomchik, M. J., Katz, J. D., Beilhack, G. F., Wicker, L. S., Sherman, L. A. Expression of diabetes-associated genes by dendritic cells and CD4 T cells drives the loss of tolerance in nonobese diabetic mice Journal of Immunology  2009 183:1533-1541  DOI:10.4049/jimmunol.0900428  PMID:19592648  PMCID:PMC2733871
  • Dai, Y. D., Marrero, I. G., Gros, P., Zaghouani, H., Wicker, L. S., Sercarz, E. E. Slc11a1 enhances the autoimmune diabetogenic T-cell response by altering processing and presentation of pancreatic islet antigens Diabetes  2009 58:156-164  DOI:10.2337/db07-1608  PMID:18984740  PMCID:PMC2606865
  • Mattner, J., Savage, P. B., Leung, P., Oertelt, S. S., Wang, V., Trivedi, O., Scanlon, S. T., Pendem, K., Teyton, L., Hart, J., Ridgway, W. M., Wicker, L. S., et al. Liver autoimmunity triggered by microbial activation of natural killer T cells Cell Host & Microbe  2008 3:304-315  DOI:10.1016/j.chom.2008.03.009  PMID:18474357  PMCID:PMC2453520
  • Hamilton-Williams, E. E., Martinez, X., Lyman, M., Hunter, K., Wicker, L. S., Sherman, L. A. The use of Idd congenic mice to identify checkpoints of peripheral tolerance to islet antigen Annals of the New York Academy of Sciences  2007 1103:118-127  DOI:10.1196/annals.1394.003  PMID:17376833
  • Martinez, X., Kreuwel, H. T. C., Redmond, W. L., Trenney, R., Hunter, K., Rosen, H., Sarvetnick, N., Wicker, L. S., Sherman, L. A. CD8+ T cell tolerance in nonobese diabetic mice is restored by insulin-dependent diabetes resistance alleles Journal of Immunology  2005 175:1677-1685  PMID:16034108
  • McAleer, M. A., Reifsnyder, P., Palmer, S. M., Prochazka, M., Love, J. M., Copeman, J. B., Powell, E. E., Rodrigues, N. R., Prins, J. B., Serreze, D. V., Delarato, N. H., Wicker, L. S., et al. Crosses of nod mice with the related non strain - a polygenic model for iddm Diabetes  1995 44:1186-1195  DOI:10.2337/diabetes.44.10.1186  PMID:7556956