recent publications

• academic article

  • Schuh, A. L., Hanna, M., Quinney, K., Wang, L., Sarkeshik, A., Yates III, J. R., Audhya, A. The VPS-20 subunit of the endosomal sorting complex ESCRT-III exhibits an open conformation in the absence of upstream activation Biochemical Journal  2015 466:625-637  DOI:10.1042/bj20141202  PMID:25588614  PMCID:PMC4384658
  • Castaneda, J., Genzor, P., van der Heijden, G. W., Sarkeshik, A., Yates III, J. R., Ingolia, N. T., Bortvin, A. Reduced pachytene piRNAs and translation underlie spermiogenic arrest in Maelstrom mutant mice EMBO Journal  2014 33:1999-2019  DOI:10.15252/embj.201386855  PMID:25063675  PMCID:PMC4195769
  • Huang, T. Y., Michael, S., Xu, T., Sarkeshik, A., Moresco, J. J., Yates, J. R., 3rd, Masliah, E., Bokoch, G. M., DerMardirossian, C. A novel Rac1 GAP splice variant relays poly-Ub accumulation signals to mediate Rac1 inactivation Molecular Biology of the Cell  2013 24:194-209  DOI:10.1091/mbc.E12-07-0565  PMID:23223568  PMCID:PMC3564530
  • Zhang, S. F., Zhou, Y. J., Sarkeshik, A., Yates, J. R., Thomson, T. M., Zhang, Z. T., Lee, E. Y. C., Lee, Mywt Identification of RNF8 as a ubiquitin ligase involved in targeting the p12 subunit of DNA polymerase δ for degradation in response to DNA damage Journal of Biological Chemistry  2013 288:2941-2950  DOI:10.1074/jbc.M112.423392  PMID:23233665  PMCID:PMC3561517
  • Mayers, J. R., Wang, L., Pramanik, J., Johnson, A., Sarkeshik, A., Wang, Y., Saengsawang, W., Yates, J. R., Audhya, A. Regulation of ubiquitin-dependent cargo sorting by multiple endocytic adaptors at the plasma membrane Proceedings of the National Academy of Sciences of the United States of America  2013 110:11857-11862  DOI:10.1073/pnas.1302918110  PMID:23818590  PMCID:PMC3718112
  • Ma, C. H., Cui, H., Hajra, S., Rowley, P. A., Fekete, C., Sarkeshik, A., Ghosh, S. K., Yates, J. R., Jayaram, M. Temporal sequence and cell cycle cues in the assembly of host factors at the yeast 2 micron plasmid partitioning locus Nucleic Acids Research  2013 41:2340-2353  DOI:10.1093/nar/gks1338  PMID:23275556  PMCID:PMC3575823
  • Aoki, T., Sarkeshik, A., Yates, J., Schedl, P. Elba, a novel developmentally regulated chromatin boundary factor is a hetero-tripartite DNA binding complex Elife  2012 1:e00171  DOI:10.7554/eLife.00171  PMID:23240086  PMCID:PMC3510454
  • Bargaje, R., Gupta, S., Sarkeshik, A., Park, R., Xu, T., Sarkar, M., Halimani, M., Roy, S. S., Yates, J., Pillai, B. Identification of novel targets for miR-29a using miRNA proteomics PLoS One  2012 7:e43243  DOI:10.1371/journal.pone.0043243  PMID:22952654  PMCID:PMC3428309
  • Shia, W. J., Okumura, A. J., Yan, M., Sarkeshik, A., Lo, M. C., Matsuura, S., Komeno, Y., Zhao, X., Nimer, S. D., Yates III, J. R., Zhang, D. E. PRMT1 interacts with AML1-ETO to promote its transcriptional activation and progenitor cell proliferative potential Blood  2012 119:4953-4962  DOI:10.1182/blood-2011-04-347476  PMID:22498736  PMCID:PMC3367897
  • Marvin, M. C., Clauder-Munster, S., Walker, S. C., Sarkeshik, A., Yates, J. R., Steinmetz, L. M., Engelke, D. R. Accumulation of noncoding RNA due to an RNase P defect in Saccharomyces cerevisiae RNA-a Publication of the RNA Society  2011 17:1441-1450  DOI:10.1261/rna.2737511  PMID:21665995  PMCID:PMC3153969
  • Paramasivam, M., Sarkeshik, A., Yates, J. R., Fernandes, M. J. G., McCollum, D. Angiomotin family proteins are novel activators of the LATS2 kinase tumor suppressor Molecular Biology of the Cell  2011 22:3725-3733  DOI:10.1091/mbc.E11-04-0300  PMID:21832154  PMCID:PMC3183025
  • Sansing, H. A., Sarkeshik, A., Yates, J. R., Patel, V., Gutkind, J. S., Yamada, K. M., Berrier, A. L. Integrin alpha beta 1, alpha(v)beta, alpha(6)beta effectors p130Cas, Src and talin regulate carcinoma invasion and chemoresistance Biochemical and Biophysical Research Communications  2011 406:171-176  DOI:10.1016/j.bbrc.2011.01.109  PMID:21291860  PMCID:PMC3102534
  • Bonner, M. K., Poole, D. S., Xu, T., Sarkeshik, A., Yates, J. R., Skop, A. R. Mitotic spindle proteomics in Chinese hamster ovary cells PLoS One  2011 6:e20489  DOI:10.1371/journal.pone.0020489  PMID:21647379  PMCID:PMC3103581
  • Schuh, A. L., Hegermann, J., Sarkeshik, A., Mayers, J. R., Schwarze, K., Yates, J. R., Eimer, S., Audhya, A., Witte, K. TFG-1 function in protein secretion and oncogenesis Nature Cell Biology  2011 13:550-558  DOI:10.1038/ncb2225  PMID:21478858  PMCID:PMC3311221
  • Wong, L. C., Costa, A., McLeod, I., Sarkeshik, A., Yates, J., Kyin, S., Perlman, D., Schedl, P. The functioning of the Drosophila CPEB protein Orb is regulated by phosphorylation and requires casein kinase 2 activity PLoS One  2011 6:e24355  DOI:10.1371/journal.pone.0024355  PMID:21949709  PMCID:PMC3176278
  • Nishimura, N., Sarkeshik, A., Nito, K., Park, S. Y., Wang, A., Carvalho, P. C., Lee, S., Caddell, D. F., Cutler, S. R., Chory, J., Yates, J. R., Schroeder, J. I. PYR/PYL/RCAR family members are major in vivo ABI1 protein phosphatase 2C-interacting proteins in Arabidopsis Plant Journal  2010 61:290-299  DOI:10.1111/j.1365-313X.2009.04054.x  PMID:19874541  PMCID:PMC2807913
  • Michelot, A., Costanzo, M., Sarkeshik, A., Boone, C., Yates, J. R., Drubin, D. G. Reconstitution and protein composition analysis of endocytic actin patches Current Biology  2010 20:1890-1899  DOI:10.1016/j.cub.2010.10.016  PMID:21035341  PMCID:PMC2998891
  • Hutson, S. L., Mui, E., Kinsley, K., Witola, W. H., Behnke, M. S., El Bissati, K., Muench, S. P., Rohrman, B., Liu, S. R., Wollmann, R., Ogata, Y., Sarkeshik, A., et al. T. gondii RP promoters & knockdown reveal molecular pathways associated with proliferation and cell-cycle arrest PLoS One  2010 5:e14057  DOI:10.1371/journal.pone.0014057  PMID:21124925  PMCID:PMC2989910
  • Curtis, C. D., Thorngren, D. L., Ziegler, Y. S., Sarkeshik, A., Yates, J. R., Nardulli, A. M. Apurinic/apyrimidinic endonuclease 1 alters estrogen receptor activity and estrogen-responsive gene expression Molecular Endocrinology  2009 23:1346-1359  DOI:10.1210/me.2009-0093  PMID:19460860  PMCID:PMC2737565
  • Shi, Y. S., Di Giammartino, D. C., Taylor, D., Sarkeshik, A., Rice, W. J., Yates, J. R., Frank, J., Manley, J. L. Molecular architecture of the human pre-mRNA 3' processing complex Molecular Cell  2009 33:365-376  DOI:10.1016/j.molcel.2008.12.028  PMID:19217410  PMCID:PMC2946185
  • Choi, S. H., Peli-Gulli, M. P., McLeod, I., Sarkeshik, A., Yates, J. R., Simanis, V., McCollum, D. Phosphorylation state defines discrete roles for monopolin in chromosome attachment and spindle elongation Current Biology  2009 19:985-995  DOI:10.1016/j.cub.2009.05.042  PMID:19523829  PMCID:PMC2726783
  • Amako, Y., Sarkeshik, A., Hotta, H., Yates, J., Siddiqui, A. Role of oxysterol binding protein in hepatitis C virus infection Journal of Virology  2009 83:9237-9246  DOI:10.1128/jvi.00958-09  PMID:19570870  PMCID:PMC2738263
  • Diop, S. B., Bertaux, K., Vasanthi, D., Sarkeshik, A., Goirand, B., Aragnol, D., Tolwinski, N. S., Cole, M. D., Pradel, J., Yates, J. R., Mishra, R. K., Graba, Y., et al. Reptin and Pontin function antagonistically with PcG and TrxG complexes to mediate Hox gene control EMBO Reports  2008 9:260-266  DOI:10.1038/embor.2008.8  PMID:18259215  PMCID:PMC2267392