recent publications

• academic article

  • Yung, Y. C., Mutoh, T., Lin, M. E., Noguchi, K., Rivera, R. R., Choi, J. W., Kingsbury, M. A., Chun, J. Lysophosphatidic acid signaling may initiate fetal hydrocephalus Science Translational Medicine  2011 3:99ra87  DOI:10.1126/scitranslmed.3002095  PMID:21900594  PMCID:PMC3653407
  • Rehen, S. K., Kingsbury, M. A., Almeida, B. S. V., Herr, D. R., Peterson, S., Chun, J. A new method of embryonic culture for assessing global changes in brain organization Journal of Neuroscience Methods  2006 158:100-108  DOI:10.1016/j.jneumeth.2006.05.025  PMID:16824613
  • Kingsbury, M. A., Yung, Y. C., Peterson, S. E., Westra, J. W., Chun, J. Aneuploidy in the normal and diseased brain Cellular and Molecular Life Sciences  2006 63:2626-2641  DOI:10.1007/s00018-006-6169-5  PMID:16952055
  • Kingsbury, M. A., Friedman, B., McConnell, M. J., Rehen, S. K., Yang, A. H., Kaushal, D., Chun, J. Aneuploid neurons are functionally active and integrated into brain circuitry Proceedings of the National Academy of Sciences of the United States of America  2005 102:6143-6147  DOI:10.1073/pnas.0408171102  PMID:15837924  PMCID:PMC1087909
  • Rehen, S. K., Yung, Y. C., McCreight, M. P., Kaushal, D., Yang, A. H., Almeida, B. S. V., Kingsbury, M. A., Cabral, K. M. S., McConnell, M. J., Anliker, B., Fontanoz, M., Chun, J. Constitutional aneuploidy in the normal human brain Journal of Neuroscience  2005 25:2176-2180  DOI:10.1523/jneurosci.4560-04.2005  PMID:15745943
  • McConnell, M. J., Kaushal, D., Yang, A. H., Kingsbury, M. A., Rehen, S. K., Treuner, K., Helton, R., Annas, E. G., Chun, J., Barlow, C. Failed clearance of aneuploid embryonic neural progenitor cells leads to excess aneuploidy in the Atm-deficient but not the Trp53-deficient adult cerebral cortex Journal of Neuroscience  2004 24:8090-8096  DOI:10.1523/jneurosci.2263-04.2004  PMID:15371510
  • Kingsbury, M. A., Rehen, S. K., Ye, X., Chun, J. Genetics and cell biology of lysophosphatidic acid receptor-mediated signaling during cortical neurogenesis Journal of Cellular Biochemistry  2004 92:1004-1012  DOI:10.1002/jcb.20061  PMID:15258921
  • Kaushal, D., Contos, J. J. A., Treuner, K., Yang, A. H., Kingsbury, M. A., Rehen, S. K., McConnell, M. J., Okabe, M., Barlow, C., Chun, J. Alteration of gene expression by chromosome loss in the postnatal mouse brain Journal of Neuroscience  2003 23:5599-5606  PMID:12843262
  • Yang, A. H., Kaushal, D., Rehen, S. K., Kriedt, K., Kingsbury, M. A., McConnell, M. J., Chun, J. Chromosome segregation defects contribute to aneuploidy in normal neural progenitor cells Journal of Neuroscience  2003 23:10454-10462  PMID:14614104
  • Kingsbury, M. A., Rehen, S. K., Contos, J. J. A., Higgins, C. M., Chun, J. Non-proliferative effects of lysophosphatidic acid enhance cortical growth and folding Nature Neuroscience  2003 6:1292-1299  DOI:10.1038/nn1157  PMID:14625558
  • Contos, J. J. A., Ishii, I., Fukushima, N., Kingsbury, M. A., Ye, X. Q., Kawamura, S., Brown, J. H., Chun, J. Characterization of lpa(2) (edg4) and lpa(1)/lpa(2) (edg2/edg4) lysophosphatidic acid receptor knockout mice: Signaling deficits without obvious phenotypic abnormality attributable to lpa(2) Molecular and Cellular Biology  2002 22:6921-6929  DOI:10.1128/mcb.22.19.6921-6929.2002  PMID:12215548
  • Ye, X. Q., Ishii, I., Kingsbury, M. A., Chun, J. Lysophosphatidic acid as a novel cell survival/apoptotic factor Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids  2002 1585:108-113  DOI:10.1016/s1388-1981(02)00330-x  PMID:12531543
  • Ye, X. Q., Fukushima, N., Kingsbury, M. A., Chun, J. Lysophosphatidic acid in neural signaling Neuroreport  2002 13:2169-2175  DOI:10.1097/01.wnr.0000044217.09266.2d  PMID:12488791
  • Fukushima, N., Weiner, J. A., Kaushal, D., Contos, J. J. A., Rehen, S. K., Kingsbury, M. A., Kim, K. Y., Chun, J. Lysophosphatidic acid influences the morphology and motility of young, postmitotic cortical neurons Molecular and Cellular Neuroscience  2002 20:271-282  DOI:10.1006/mcne.2002.1123  PMID:12093159
  • Ishii, I., Ye, X. Q., Friedman, B., Kawamura, S., Contos, J. J. A., Kingsbury, M. A., Yang, A. H., Zhang, G. F., Brown, J. H., Chun, J. Marked perinatal lethality and cellular signaling deficits in mice null for the two sphingosine 1-phosphate (S1p) receptors, S1p(2)/LP(B2)/EDG-5 and S1P(3)/LP(B3)/EDG-3 Journal of Biological Chemistry  2002 277:25152-25159  DOI:10.1074/jbc.M200137200  PMID:12006579
  • Rehen, S. K., McConnell, M. J., Kaushal, D., Kingsbury, M. A., Yang, A. H., Chun, J. Chromosomal variation in neurons of the developing and adult mammalian nervous system Proceedings of the National Academy of Sciences of the United States of America  2001 98:13361-13366  DOI:10.1073/pnas.231487398  PMID:11698687  PMCID:PMC60876
  • Ishii, I., Friedman, B., Ye, X. Q., Kawamura, S., McGiffert, C., Contos, J. J. A., Kingsbury, M. A., Zhang, G. F., Brown, J. H., Chun, J. Selective loss of sphingosine 1-phosphate signaling with no obvious phenotypic abnormality in mice lacking its G protein-coupled receptor, lPB3/EDG-3 Journal of Biological Chemistry  2001 276:33697-33704  DOI:10.1074/jbc.M104441200  PMID:11443127