recent publications
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academic article
- Yung, Y. C., Mutoh, T., Lin, M. E., Noguchi, K., Rivera, R. R., Choi, J. W., Kingsbury, M. A., Chun, J. Lysophosphatidic acid signaling may initiate fetal hydrocephalus Science Translational Medicine 2011 3:99ra87 DOI:10.1126/scitranslmed.3002095 PMID:21900594 PMCID:PMC3653407
- Rehen, S. K., Kingsbury, M. A., Almeida, B. S. V., Herr, D. R., Peterson, S., Chun, J. A new method of embryonic culture for assessing global changes in brain organization Journal of Neuroscience Methods 2006 158:100-108 DOI:10.1016/j.jneumeth.2006.05.025 PMID:16824613
- Kingsbury, M. A., Yung, Y. C., Peterson, S. E., Westra, J. W., Chun, J. Aneuploidy in the normal and diseased brain Cellular and Molecular Life Sciences 2006 63:2626-2641 DOI:10.1007/s00018-006-6169-5 PMID:16952055
- Kingsbury, M. A., Friedman, B., McConnell, M. J., Rehen, S. K., Yang, A. H., Kaushal, D., Chun, J. Aneuploid neurons are functionally active and integrated into brain circuitry Proceedings of the National Academy of Sciences of the United States of America 2005 102:6143-6147 DOI:10.1073/pnas.0408171102 PMID:15837924 PMCID:PMC1087909
- Rehen, S. K., Yung, Y. C., McCreight, M. P., Kaushal, D., Yang, A. H., Almeida, B. S. V., Kingsbury, M. A., Cabral, K. M. S., McConnell, M. J., Anliker, B., Fontanoz, M., Chun, J. Constitutional aneuploidy in the normal human brain Journal of Neuroscience 2005 25:2176-2180 DOI:10.1523/jneurosci.4560-04.2005 PMID:15745943
- McConnell, M. J., Kaushal, D., Yang, A. H., Kingsbury, M. A., Rehen, S. K., Treuner, K., Helton, R., Annas, E. G., Chun, J., Barlow, C. Failed clearance of aneuploid embryonic neural progenitor cells leads to excess aneuploidy in the Atm-deficient but not the Trp53-deficient adult cerebral cortex Journal of Neuroscience 2004 24:8090-8096 DOI:10.1523/jneurosci.2263-04.2004 PMID:15371510
- Kingsbury, M. A., Rehen, S. K., Ye, X., Chun, J. Genetics and cell biology of lysophosphatidic acid receptor-mediated signaling during cortical neurogenesis Journal of Cellular Biochemistry 2004 92:1004-1012 DOI:10.1002/jcb.20061 PMID:15258921
- Kingsbury, M. A., Rehen, S. K., Contos, J. J. A., Higgins, C. M., Chun, J. Non-proliferative effects of lysophosphatidic acid enhance cortical growth and folding Nature Neuroscience 2003 6:1292-1299 DOI:10.1038/nn1157 PMID:14625558
- Yang, A. H., Kaushal, D., Rehen, S. K., Kriedt, K., Kingsbury, M. A., McConnell, M. J., Chun, J. Chromosome segregation defects contribute to aneuploidy in normal neural progenitor cells Journal of Neuroscience 2003 23:10454-10462 PMID:14614104
- Kaushal, D., Contos, J. J. A., Treuner, K., Yang, A. H., Kingsbury, M. A., Rehen, S. K., McConnell, M. J., Okabe, M., Barlow, C., Chun, J. Alteration of gene expression by chromosome loss in the postnatal mouse brain Journal of Neuroscience 2003 23:5599-5606 PMID:12843262
- Ye, X. Q., Ishii, I., Kingsbury, M. A., Chun, J. Lysophosphatidic acid as a novel cell survival/apoptotic factor Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids 2002 1585:108-113 DOI:10.1016/s1388-1981(02)00330-x PMID:12531543
- Ye, X. Q., Fukushima, N., Kingsbury, M. A., Chun, J. Lysophosphatidic acid in neural signaling Neuroreport 2002 13:2169-2175 DOI:10.1097/01.wnr.0000044217.09266.2d PMID:12488791
- Contos, J. J. A., Ishii, I., Fukushima, N., Kingsbury, M. A., Ye, X. Q., Kawamura, S., Brown, J. H., Chun, J. Characterization of lpa(2) (edg4) and lpa(1)/lpa(2) (edg2/edg4) lysophosphatidic acid receptor knockout mice: Signaling deficits without obvious phenotypic abnormality attributable to lpa(2) Molecular and Cellular Biology 2002 22:6921-6929 DOI:10.1128/mcb.22.19.6921-6929.2002 PMID:12215548
- Ishii, I., Ye, X. Q., Friedman, B., Kawamura, S., Contos, J. J. A., Kingsbury, M. A., Yang, A. H., Zhang, G. F., Brown, J. H., Chun, J. Marked perinatal lethality and cellular signaling deficits in mice null for the two sphingosine 1-phosphate (S1p) receptors, S1p(2)/LP(B2)/EDG-5 and S1P(3)/LP(B3)/EDG-3 Journal of Biological Chemistry 2002 277:25152-25159 DOI:10.1074/jbc.M200137200 PMID:12006579
- Fukushima, N., Weiner, J. A., Kaushal, D., Contos, J. J. A., Rehen, S. K., Kingsbury, M. A., Kim, K. Y., Chun, J. Lysophosphatidic acid influences the morphology and motility of young, postmitotic cortical neurons Molecular and Cellular Neuroscience 2002 20:271-282 DOI:10.1006/mcne.2002.1123 PMID:12093159
- Rehen, S. K., McConnell, M. J., Kaushal, D., Kingsbury, M. A., Yang, A. H., Chun, J. Chromosomal variation in neurons of the developing and adult mammalian nervous system Proceedings of the National Academy of Sciences of the United States of America 2001 98:13361-13366 DOI:10.1073/pnas.231487398 PMID:11698687 PMCID:PMC60876
- Ishii, I., Friedman, B., Ye, X. Q., Kawamura, S., McGiffert, C., Contos, J. J. A., Kingsbury, M. A., Zhang, G. F., Brown, J. H., Chun, J. Selective loss of sphingosine 1-phosphate signaling with no obvious phenotypic abnormality in mice lacking its G protein-coupled receptor, lPB3/EDG-3 Journal of Biological Chemistry 2001 276:33697-33704 DOI:10.1074/jbc.M104441200 PMID:11443127