recent publications

• academic article

  • del Rincon, S. V., Widschwendter, M., Sun, D., Ekholm-Reed, S., Tat, J., Teixeira, L. K., Ellederova, Z., Grolieres, E., Reed, S. I., Spruck, C. Cks overexpression enhances chemotherapeutic efficacy by overriding DNA damage checkpoints Oncogene  2015 34:1961-1967  DOI:10.1038/onc.2014.137  PMID:24858038  PMCID:PMC4245389
  • Akhoondi, S., Sun, D., von der Lehr, N., Apostolidou, S., Klotz, K., Maljukova, A., Cepeda, D., Fiegl, H., Dofou, D., Marth, C., Mueller-Holzner, E., Corcoran, M., et al. Fbxw7/hcdc4 is a general tumor suppressor in human cancer Cancer Research  2007 67:9006-9012  DOI:10.1158/0008-5472.can-07-1320  PMID:17909001
  • Keller, U. B., Old, J. B., Dorsey, F. C., Nilsson, J. A., Nilsson, L., MacLean, K. H., Chung, L., Yang, C. Y., Spruck, C., Boyd, K., Reed, S. I., Cleveland, J. L. Myc targets cks1 to provoke the suppression of p27(kip1), proliferation and lymphomagenesis EMBO Journal  2007 26:2562-2574  DOI:10.1038/sj.emboj.7601691  PMID:17464290  PMCID:PMC1868903
  • Spruck, C., Sun, D., Fiegl, H., Marth, C., Mueller-Holzner, E., Goebel, G., Widschwendter, M., Reed, S. I. Detection of low molecular weight derivatives of cyclin e1 is a function of cyclin e1 protein levels in breast cancer Cancer Research  2006 66:7355-7360  DOI:10.1158/0008-5472.can-05-3240  PMID:16849587
  • Spruck, C., Strohmaier, H., Watson, M., Smith, A. P. L., Ryan, A., Krek, W., Reed, S. I. A cdk-independent function of mammalian cks1: Targeting of scfskp2 to the cdk inhibitor p27(kip1) Molecular Cell  2001 7:639-650  DOI:10.1016/s1097-2765(01)00210-6  PMID:11463388