recent publications

• academic article

  • Yin, Y., Zhou, H., Liu, X., Chen, H., Wu, F., Zhang, H., Tao, R., Cheng, F., Feng, Y. A metal-free and recyclable synthesis of benzothiazoles using thiourea as a sulfur surrogate Tetrahedron Letters  2015 56:1709-1712  DOI:10.1016/j.tetlet.2015.02.054
  • Du, S. X., Xu, L., Zhang, W. G., Tang, S., Boenig, R. I., Chen, H., Mariano, E. B., Zwick, M. B., Parren, Pwhi, Burton, D. R., Wrin, T., Petropoulos, C. J., et al. A directed molecular evolution approach to improved immunogenicity of the hiv-1 envelope glycoprotein PLoS One  2011 6:e20927  DOI:10.1371/journal.pone.0020927  PMID:21738594  PMCID:PMC3126809
  • Nakamaru-Ogiso, E., Kao, M. C., Chen, H., Sinha, S. C., Yagi, T., Ohnishi, T. The membrane subunit nuol(nd5) is involved in the indirect proton pumping mechanism of escherichia coli complex i Journal of Biological Chemistry  2010 285:39070-39078  DOI:10.1074/jbc.M110.157826  PMID:20826797  PMCID:PMC2998099
  • Chan, C. S., Chen, H., Bradley, A., Dragatsis, I., Rosenmund, C., Davis, R. L. α8-integrins are required for hippocampal long-term potentiation but not for hippocampal-dependent learning Genes Brain and Behavior  2010 9:402-410  DOI:10.1111/j.1601-183X.2010.00569.x  PMID:20132319  PMCID:PMC2925190
  • Gonzalez, R., Jennings, L. L., Knuth, M., Orth, A. P., Klock, H. E., Ou, W., Feuerhelm, J., Hull, M. V., Koesema, E., Wang, Y. P., Zhang, J., Wu, C. L., et al. Screening the mammalian extracellular proteome for regulators of embryonic human stem cell pluripotency Proceedings of the National Academy of Sciences of the United States of America  2010 107:3552-3557  DOI:10.1073/pnas.0914019107  PMID:20133595  PMCID:PMC2840467
  • Adler, J. T., Cook, M., Luo, Y. G., Pitt, S. C., Ju, J. H., Li, W. L., Shen, B., Kunnimalaiyaan, M., Chen, H. Tautomycetin and tautomycin suppress the growth of medullary thyroid cancer cells via inhibition of glycogen synthase kinase-3 beta Molecular Cancer Therapeutics  2009 8:914-920  DOI:10.1158/1535-7163.mct-08-0712  PMID:19372564  PMCID:PMC2670470
  • Pinchot, S. N., Adler, J. T., Luo, Y. G., Ju, J. H., Li, W. L., Shen, B., Kunnimalaiyaan, M., Chen, H. Tautomycin suppresses growth and neuroendocrine hormone markers in carcinoid cells through activation of the raf-1 pathway American Journal of Surgery  2009 197:313-318  DOI:10.1016/j.amjsurg.2008.10.007  PMID:19245907  PMCID:PMC2664746
  • Borevitz, J. O., Hazen, S. P., Michael, T. P., Morris, G. P., Baxter, I. R., Hu, T. T., Chen, H., Werner, J. D., Nordborg, M., Salf, D. E., Kay, S. A., Chory, J., et al. Genome-wide patterns of single-feature polymorphism in Arabidopsis thaliana Proceedings of the National Academy of Sciences of the United States of America  2007 104:12057-12062  DOI:10.1073/pnas.0705323104  PMID:17626786  PMCID:PMC1914337
  • Roush, W. R., Chen, H., Reilly, M. L. Studies on the synthesis of kijanolide: synthesis of an advanced seco-acid intermediate Heterocycles  2002 58:259-282  DOI:10.3987/COM-02-S(M)17
  • Frank, S. A., Chen, H., Kunz, R. K., Schnaderbeck, M. J., Roush, W. R. Use of thallium(I) ethoxide in Suzuki cross coupling reactions Organic Letters  2000 2:2691-2694  DOI:10.1021/ol0062446  PMID:10990429
  • Schleim, K. D., Jacks, T., Cunningham, P., Feeney, W., Frazier, E. G., Niebauer, G. W., Zhang, D., Chen, H., Smith, R. G., Hickey, G. Increases in circulating insulin-like growth factor I levels by the oral growth hormone secretagogue MK-0677 in the beagle are dependent upon pituitary mediation Endocrinology  1999 140:1552-1558  DOI:10.1210/en.140.4.1552  PMID:10098487
  • Scheidt, K. A., Chen, H., Follows, B. C., Chemler, S. R., Coffey, D. S., Roush, W. R. Tris(dimethylamino)sulfonium difluorotrimethylsilicate, a mild reagent for the removal of silicon protecting groups Journal of Organic Chemistry  1998 63:6436-6437  DOI:10.1021/jo981215i
  • Foster, M. H., Liu, Q. G., Chen, H., Nemazee, D., Cooperstone, B. G. Anti-laminin reactivity and glomerular immune deposition by in vitro recombinant antibodies Autoimmunity  1997 26:231-243  DOI:10.3109/08916939709008029  PMID:9543184
  • Jacks, T., Smith, R., Judith, F., Schleim, K., Frazier, E., Chen, H., Krupa, D., Hora, D., Nargund, R., Patchett, A., Hickey, G. MK-0677, a potent, novel, orally active growth hormone (GH) secretagogue: GH, insulin-like growth factor I, and other hormonal responses in Beagles Endocrinology  1996 137:5284-5289  DOI:10.1210/en.137.12.5284  PMID:8940347
  • Chang, C. H., Rickes, E. L., McGuire, L., Frazier, E., Chen, H., Barakat, K., Nargund, R., Patchett, A., Smith, R. G., Hickey, G. J. Growth hormone (GH) and insulin-like growth factor I responses after treatments with an orally active GH secretagogue L-163,255 in swine Endocrinology  1996 137:4851-4856  DOI:10.1210/en.137.11.4851  PMID:8895356
  • Hickey, G. J., Drisko, J., Faidley, T., Chang, C., Anderson, L. L., Nicolich, S., McGuire, L., Rickes, E., Krupa, D., Feeney, W., Friscino, B., Cunningham, P., et al. Mediation by the central nervous system is critical to the in vivo activity of the GH secretagogue L-692,585 Journal of Endocrinology  1996 148:371-380  DOI:10.1677/joe.0.1480371  PMID:8699151
  • Jacks, T., Hickey, G., Judith, F., Taylor, J., Chen, H., Krupa, D., Feeney, W., Schoen, W., Ok, D., Fisher, M., Wyvratt, M., Smith, R. Effects of acute and repeated intravenous administration of L-692,585, a novel non-peptidyl growth hormone secretagogue, on plasma growth hormone, IGF-1, ACTH, cortisol, prolactin, insulin, and thyroxine levels in beagles Journal of Endocrinology  1994 143:399-406  DOI:10.1677/joe.0.1430399  PMID:7830002
  • Ogino, Y., Chen, H., Manoury, E., Shibata, T., Beller, M., Lubben, D., Sharpless, K. B. A ligand structure-enantioselectivity relationship for the osmium-catalyzed asymmetric dihydroxylation of olefins Tetrahedron Letters  1991 32:5761-5764  DOI:10.1016/s0040-4039(00)93549-4
  • Ogino, Y., Chen, H., Kwong, H. L., Sharpless, K. B. On the timing of hydrolysis reoxidation in the osmium-catalyzed asymmetric dihydroxylation of olefins using potassium ferricyanide as the reoxidant Tetrahedron Letters  1991 32:3965-3968  DOI:10.1016/0040-4039(91)80601-2
  • Dilella, A. G., Hope, D. A., Chen, H., Trumbauer, M., Schwartz, R. J., Smith, R. G. Utility of firefly luciferase as a reporter gene for promoter activity in transgenic mice Nucleic Acids Research  1988 16:4159-4159  DOI:10.1093/nar/16.9.4159  PMID:3375079  PMCID:PMC336585