recent publications

• academic article

  • Matsubara, Y., Kato, T., Kashimada, K., Tanaka, H., Zhi, Z., Ichinose, S., Mizutani, S., Morio, T., Chiba, T., Ito, Y., Saga, Y., Takada, S., et al. TALEN-mediated gene disruption on Y chromosome reveals critical role of EIF2S3Y in mouse spermatogenesis Stem Cells and Development  2015 24:1164-1170  DOI:10.1089/scd.2014.0466  PMID:25579647  PMCID:PMC4425228
  • Otabe, K., Nakahara, H., Hasegawa, A., Matsukawa, T., Ayabe, F., Onizuka, N., Inui, M., Takada, S., Ito, Y., Sekiya, I., Muneta, T., Lotz, M., et al. Transcription factor Mohawk controls tenogenic differentiation of bone marrow mesenchymal stem cells in vitro and in vivo Journal of Orthopaedic Research  2015 33:1-8  DOI:10.1002/jor.22750  PMID:25312837  PMCID:PMC4294629
  • Hart, J. R., Garner, A. L., Yu, J., Ito, Y., Sun, M. H., Ueno, L., Rhee, J. K., Baksh, M. M., Stefan, E., Hartl, M., Bister, K., Vogt, P. K., et al. Inhibitor of MYC identified in a Krohnke pyridine library Proceedings of the National Academy of Sciences of the United States of America  2014 111:12556-12561  DOI:10.1073/pnas.1319488111  PMID:25114221  PMCID:PMC4151726
  • Onizuka, N., Ito, Y., Inagawa, M., Nakahara, H., Takada, S., Lotz, M., Toyama, Y., Asahara, H. The Mohawk homeobox transcription factor regulates the differentiation of tendons and volar plates Journal of Orthopaedic Science  2014 19:172-180  DOI:10.1007/s00776-013-0485-z  PMID:24166359  PMCID:PMC3943675
  • Takada, S., Sato, T., Ito, Y., Yamashita, S., Kato, T., Kawasumi, M., Kanai-Azuma, M., Igarashi, A., Kato, T., Tamano, M., Asahara, H. Targeted gene deletion of miRNAs in mice by TALEN system PLoS One  2013 8:e76004  DOI:10.1371/journal.pone.0076004  PMID:24146809  PMCID:PMC3797721
  • Nakahara, H., Hasegawa, A., Otabe, K., Ayabe, F., Matsukawa, T., Onizuka, N., Ito, Y., Ozaki, T., Lotz, M. K., Asahara, H. Transcription factor Mohawk and the pathogenesis of human anterior cruciate ligament degradation Arthritis and Rheumatism  2013 65:2081-2089  DOI:10.1002/art.38020  PMID:23686683  PMCID:PMC3840305
  • Watanabe, T., Oyama, T., Asada, M., Harada, D., Ito, Y., Inagawa, M., Suzuki, Y., Sugano, S., Katsube, K., Karsenty, G., Komori, T., Kitagawa, M., et al. MAML1 enhances the transcriptional activity of Runx2 and plays a role in bone development PLoS Genetics  2013 9:e1003132  DOI:10.1371/journal.pgen.1003132  PMID:23326237  PMCID:PMC3542067
  • Ito, Y., Kayama, T., Asahara, H. A systems approach and skeletal myogenesis Comparative and Functional Genomics  2012 759407  DOI:10.1155/2012/759407  PMID:22991503  PMCID:PMC3443578
  • Pejchal, R., Doores, K. J., Walker, L. M., Khayat, R., Huang, P. S., Wang, S. K., Stanfield, R. L., Julien, J. P., Ramos, A., Crispin, M., Depetris, R., Katpally, U., et al. A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield Science  2011 334:1097-1103  DOI:10.1126/science.1213256  PMID:21998254  PMCID:PMC3280215
  • Ito, Y., Toriuchi, N., Yoshitaka, T., Ueno-Kudoh, H., Sato, T., Yokoyama, S., Nishida, K., Akimoto, T., Takahashi, M., Miyaki, S., Asahara, H. The Mohawk homeobox gene is a critical regulator of tendon differentiation Proceedings of the National Academy of Sciences of the United States of America  2010 107:10538-10542  DOI:10.1073/pnas.1000525107  PMID:20498044  PMCID:PMC2890854
  • Miyaki, S., Sato, T., Inoue, A., Otsuki, S., Ito, Y., Yokoyama, S., Kato, Y., Takemoto, F., Nakasa, T., Yamashita, S., Takada, S., Lotz, M. K., et al. MicroRNA-140 plays dual roles in both cartilage development and homeostasis Genes & Development  2010 24:1173-1185  DOI:10.1101/gad.1915510  PMID:20466812  PMCID:PMC2878654
  • Higashiyama, R., Miyaki, S., Yamashita, S., Yoshitaka, T., Lindman, G., Ito, Y., Sasho, T., Takahashi, K., Lotz, M., Asahara, H. Correlation between MMP-13 and HDAC7 expression in human knee osteoarthritis Modern Rheumatology  2010 20:11-17  DOI:10.1007/s10165-009-0224-7  PMID:19784544  PMCID:PMC2818344
  • Yokoyama, S., Ito, Y., Ueno-Kudoh, H., Shimizu, H., Uchibe, K., Albini, S., Mitsuoka, K., Miyaki, S., Kiso, M., Nagai, A., Hikata, T., Osada, T., et al. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58 Developmental Cell  2009 17:836-848  DOI:10.1016/j.devcel.2009.10.011  PMID:20059953  PMCID:PMC3110151
  • Aubin, Y., Ito, Y., Paulson, J. C., Prestegard, J. H. Structure and dynamics of the sialic-acid moiety of g(m3)-ganglioside at the surface of a magnetically oriented membrane Biochemistry  1993 32:13405-13413  DOI:10.1021/bi00212a005  PMID:8257677
  • Ito, Y., Paulson, J. C. Combined use of trans-sialidase and sialyltransferase for enzymatic-synthesis of alpha-neuac2-- 3-beta-gal-or Journal of the American Chemical Society  1993 115:7862-7863  DOI:10.1021/ja00070a036
  • Morgan, I. M., Asano, M., Havarstein, L. S., Ishikawa, H., Hiiragi, T., Ito, Y., Vogt, P. K. Amino-acid substitutions modulate the effect of jun on transformation, transcriptional activation and DNA-replication Oncogene  1993 8:1135-1140  PMID:8479738
  • Ito, Y., Gaudino, J. J., Paulson, J. C. Synthesis of bioactive sialosides Pure and Applied Chemistry  1993 65:753-762  DOI:10.1351/pac199365040753
  • Ito, Y., Paulson, J. C. A novel strategy for synthesis of ganglioside-gm3 using an enzymatically produced sialoside glycosyl donor Journal of the American Chemical Society  1993 115:1603-1605  DOI:10.1021/ja00057a071
  • Reed, L. A., Ito, Y., Masamune, S., Sharpless, K. B. Synthesis of saccharides and related polyhydroxylated natural-products .4. Alpha-d-c-glycopyranoside and beta-d-c-glycopyranoside (2,6-dialkyl-substituted tetrahydropyrans) Journal of the American Chemical Society  1982 104:6468-6470  DOI:10.1021/ja00387a062