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Sequence-specific h-1, c-13 and n-15 assignment of the tmp-resistant dihydrofolate reductase mutant dhfr(f98y) in the ternary complex with tmp and nadph

Academic Article
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Overview

authors

  • Altmann, S.
  • Labhardt, A. M.
  • Senn, H.
  • Wuthrich, Kurt

publication date

  • 1997

journal

  • Journal of Biomolecular NMR  Journal

subject areas

  • Folic Acid Antagonists
  • Magnetic Resonance Spectroscopy
  • Mutation
  • NADP
  • Protein Conformation
  • Staphylococcus aureus
  • Tetrahydrofolate Dehydrogenase
  • Trimethoprim
  • Trimethoprim Resistance
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Research

keywords

  • NMR assignments
  • antibiotics resistance
  • dihydrofolate reductase
  • drug design
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Identity

International Standard Serial Number (ISSN)

  • 0925-2738

Digital Object Identifier (DOI)

  • 10.1023/a:1018315131994

PubMed ID

  • 9255948
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Additional Document Info

start page

  • 445

end page

  • 446

volume

  • 9

issue

  • 4

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