recent publications

• academic article

  • Madani, N., Schon, A., Princiotto, A. M., LaLonde, J. M., Courter, J. R., Soeta, T., Ng, D., Wang, L. P., Brower, E. T., Xiang, S. H., Do Kwon, Y., Huang, C. C., et al. Small-molecule cd4 mimics interact with a highly conserved pocket on hiv-1 gp120 Structure  2008 16:1689-1701  DOI:10.1016/j.str.2008.09.005  PMID:19000821  PMCID:PMC2597202
  • Huang, C. C., Lam, S. N., Acharya, P., Tang, M., Xiang, S. H., Hussan, S. S. U., Stanfield, R. L., Robinson, J., Sodroski, J., Wilson, I. A., Wyatt, R., Bewley, C. A., et al. Structures of the ccr5 n terminus and of a tyrosine-sulfated antibody with hiv-1 gp120 and cd4 Science  2007 317:1930-1934  DOI:10.1126/science.1145373  PMID:17901336  PMCID:PMC2278242
  • Dey, B., Pancera, M., Svehla, K., Shu, Y., Xiang, S. H., Vainshtein, J., Li, Y. X., Sodroski, J., Kwong, P. D., Mascola, J. R., Wyatt, R. Characterization of human immunodeficiency virus type 1 monomeric and trimeric gp120 glycoproteins stabilized in the cd4-bound state: Antigenicity, biophysics, and immunogenicity Journal of Virology  2007 81:5579-5593  DOI:10.1128/jvi.02500-06  PMID:17360741
  • Zhou, T. Q., Xu, L., Dey, B., Hessell, A. J., Van Ryk, D., Xiang, S. H., Yang, X., Zhang, M. Y., Zwick, M. B., Arthos, J., Burton, D. R., Dimitrov, D. S., et al. Structural definition of a conserved neutralization epitope on HIV-1 gp120 Nature  2007 445:732-737  DOI:10.1038/nature05580  PMID:17301785  PMCID:PMC2584968
  • Xiang, S. H., Farzan, M., Si, Z. H., Madani, N., Wang, L., Rosenberg, E., Robinson, J., Sodroski, J. Functional mimicry of a human immunodeficiency virus type 1 coreceptor by a neutralizing monoclonal antibody Journal of Virology  2005 79:6068-6077  DOI:10.1128/jvi.79.10.6068-6077.2005  PMID:15857992
  • Xiang, S. H., Kwong, P. D., Gupta, R., Rizzuto, C. D., Casper, D. J., Wyatt, R., Wang, L. P., Hendrickson, W. A., Doyle, M. L., Sodroski, J. Mutagenic stabilization and/or disruption of a cd4-bound state reveals distinct conformations of the human immunodeficiency virus type 1 gp120 envelope glycoprotein Journal of Virology  2002 76:9888-9899  DOI:10.1128/jvi.76.19.9888-9899.2002  PMID:12208966