recent publications
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academic article
- Reyes, V. M., Greasley, S. E., Stura, E. A., Beardsley, G. P., Wilson, I. A. Crystallization and preliminary crystallographic investigations of avian 5-aminoimidazole-4-carboxamide ribonucleotide transformylase-inosine monophosphate cyclohydrolase expressed in escherichia coli Acta Crystallographica Section D-Biological Crystallography 2000 56:1051-1054 DOI:10.1107/s0907444900007800 PMID:10944351
- Prasad, G. S., Stura, E. A., Elder, J. H., Stout, C. D. Structures of feline immunodeficiency virus dutp pyrophosphatase and its nucleotide complexes in three crystal forms Acta Crystallographica Section D-Biological Crystallography 2000 56:1100-1109 DOI:10.1107/s0907444900009197 PMID:10957629
- Stanfield, R. L., Cabezas, E., Satterthwait, A. C., Stura, E. A., Profy, A. T., Wilson, I. A. Dual conformations for the hiv-1 gp120 v3 loop in complexes with different neutralizing fabs Structure with Folding & Design 1999 7:131-142 DOI:10.1016/s0969-2126(99)80020-3 PMID:10368281
- Livnah, O., Johnson, D. L., Stura, E. A., Farrell, F. X., Barbone, F. P., You, Y., Liu, K. D., Goldsmith, M. A., He, W., Krause, C. D., Pestka, S., Jolliffe, L. K., et al. An antagonist peptide epo receptor complex suggests that receptor dimerization is not sufficient for activation Nature Structural Biology 1998 5:993-1004 DOI:10.1038/2965 PMID:9808045
- Heine, A., Stura, E. A., Yli-Kauhaluoma, J. T., Gao, C., Deng, Q. L., Beno, B. R., Houk, K. N., Janda, K. D., Wilson, I. A. An antibody exo Diels-Alderase inhibitor complex at 1.95 Å resolution Science 1998 279:1934-1940 DOI:10.1126/science.279.5358.1934 PMID:9506943
- Scott, C. A., Garcia, K. C., Stura, E. A., Peterson, P. A., Wilson, I. A., Teyton, L. Engineering protein for X-ray crystallography: the murine major histocompatibility complex class II molecule I-A(d) Protein Science 1998 7:413-418 DOI:10.1002/pro.5560070222 PMID:9521118 PMCID:PMC2143914
- Johnson, D. L., Farrell, F. X., Barbone, F. P., McMahon, F. J., Tullai, J., Hoey, K., Livnah, O., Wrighton, N. C., Middleton, S. A., Loughney, D. A., Stura, E. A., Dower, W. J., et al. Identification of a 13 amino acid peptide mimetic of erythropoietin and description of amino acids critical for the mimetic activity of emp1 Biochemistry 1998 37:3699-3710 DOI:10.1021/bi971956y PMID:9521688
- Stout, C. D., Stura, E. A., McRee, D. E. Structure of azotobacter vinelandii 7fe ferredoxin at 1.35 Å resolution and determination of the fe-s bonds with 0.01 Å accuracy Journal of Molecular Biology 1998 278:629-639 DOI:10.1006/jmbi.1998.1732 PMID:9600844
- Huang, M. D., Syed, R., Stura, E. A., Stone, M. J., Stefanko, R. S., Ruf, W., Edgington, T. S., Wilson, I. A. The mechanism of an inhibitory antibody on TF-initiated blood coagulation revealed by the crystal structures of human tissue factor, Fab 5G9 and TF.G9 complex Journal of Molecular Biology 1998 275:873-894 DOI:10.1006/jmbi.1997.1512 PMID:9480775
- Zeng, Z. H., Castano, A. R., Segelke, B. W., Stura, E. A., Peterson, P. A., Wilson, I. A. Crystal structure of mouse cd1: An mhc-like fold with a large hydrophobic binding groove Science 1997 277:339-345 DOI:10.1126/science.277.5324.339 PMID:9219685
- Barbas, C. F., Heine, A., Zhong, G. F., Hoffmann, T., Gramatikova, S., Bjornestedt, R., List, B., Anderson, J., Stura, E. A., Wilson, I. A., Lerner, R. A. Immune versus natural selection: Antibody aldolases with enzymic rates but broader scope Science 1997 278:2085-2092 DOI:10.1126/science.278.5346.2085 PMID:9405338
- He, M., Gani, M., Livnah, O., Stura, E. A., Beale, D., Coley, J., Wilson, I. A., Taussig, M. J. Sequence, specificity and crystallization of an oestrone-3-glucuronide antibody (3910) Immunology 1997 90:632-639 DOI:10.1046/j.1365-2567.1997.00099.x PMID:9176119
- Garcia, K. C., Tallquist, M. D., Pease, L. R., Brunmark, A., Scott, C. A., Degano, M., Stura, E. A., Peterson, P. A., Wilson, I. A., Teyton, L. αβ T cell receptor interactions with syngeneic and allogeneic ligands: affinity measurements and crystallization Proceedings of the National Academy of Sciences of the United States of America 1997 94:13838-13843 DOI:10.1073/pnas.94.25.13838 PMID:9391114 PMCID:PMC28394
- Prasad, G. S., McRee, D. E., Stura, E. A., Levitt, D. G., Lee, H. C., Stout, C. D. Crystal structure of aplysia adp ribosyl cyclase, a homologue of the bifunctional ectozyme cd38 Nature Structural Biology 1996 3:957-964 DOI:10.1038/nsb1196-957 PMID:8901875
- Prasad, G. S., Stura, E. A., McRee, D. E., Laco, G. S., HasselkusLight, C., Elder, J. H., Stout, C. D. Crystal structure of dutp pyrophosphatase from feline immunodeficiency virus Protein Science 1996 5:2429-2437 DOI:10.1002/pro.5560051205 PMID:8976551 PMCID:PMC2143329
- Stura, E. A., Ruf, W., Wilson, I. A. Crystallization and preliminary crystallographic data for a ternary complex between tissue factor, factor viia and a bpti-derived inhibitor Journal of Crystal Growth 1996 168:260-269 DOI:10.1016/0022-0248(96)00329-6
- Livnah, O., Stura, E. A., Johnson, D. L., Middleton, S. A., Mulcahy, L. S., Wrighton, N. C., Dower, W. J., Jolliffe, L. K., Wilson, I. A. Functional mimicry of a protein hormone by a peptide agonist: The epo receptor complex at 2.8 Å Science 1996 273:464-471 DOI:10.1126/science.273.5274.464 PMID:8662530
- Schalk, I., Zeng, K., Wu, S. K., Stura, E. A., Matteson, J., Huang, M. D., Tandon, A., Wilson, I. A., Balch, W. E. Structure and mutational analysis of Rab GDP-dissociation inhibitor Nature 1996 381:42-48 DOI:10.1038/381042a0 PMID:8609986
- Fremont, D. H., Stura, E. A., Matsumura, M., Peterson, P. A., Wilson, I. A. Crystal-structure of an h-2k(b)-ovalbumin peptide complex reveals the interplay of primary and secondary anchor positions in the major histocompatibility complex binding groove Proceedings of the National Academy of Sciences of the United States of America 1995 92:2479-2483 DOI:10.1073/pnas.92.7.2479 PMID:7708669
- Stura, E. A., Ghosh, S., Garciajunceda, E., Chen, L. R., Wong, C. H., Wilson, I. A. Crystallization and preliminary crystallographic data for class-i deoxyribose-5-phosphate aldolase from escherichia-coli - an application of reverse screening Proteins-Structure Function and Genetics 1995 22:67-72 DOI:10.1002/prot.340220110 PMID:7675789
- Klein, C., Chen, P., Arevalo, J. H., Stura, E. A., Marolewski, A., Warren, M. S., Benkovic, S. J., Wilson, I. A. Towards structure-based drug design - crystal-structure of a multisubstrate adduct complex of glycinamide ribonucleotide transformylase at 1.96 Å resolution Journal of Molecular Biology 1995 249:153-175 DOI:10.1006/jmbi.1995.0286 PMID:7776369
- Diller, T. C., Shaw, A., Stura, E. A., Vacquier, V. D., Stout, C. D. Acid ph crystallization of the basic protein lysin from the spermatozoa of red abalone (haliotis rufescens) Acta Crystallographica Section D-Biological Crystallography 1994 50:620-626 DOI:10.1107/s0907444993013356 PMID:15299426
- Churchill, M. E. A., Stura, E. A., Pinilla, C., Appel, J. R., Houghten, R. A., Kono, D. H., Balderas, R. S., Fieser, G. G., Schulzegahmen, U., Wilson, I. A. Crystal-structure of a peptide complex of antiinfluenza peptide antibody-Fab-26/9 - comparison of 2 different antibodies bound to the same peptide antigen Journal of Molecular Biology 1994 241:534-556 DOI:10.1006/jmbi.1994.1530 PMID:7520084
- Ghiara, J. B., Stura, E. A., Stanfield, R. L., Profy, A. T., Wilson, I. A. Crystal-structure of the principal neutralization site of hiv-1 Science 1994 264:82-85 DOI:10.1126/science.7511253 PMID:7511253
- Schalk, I. J., Stura, E. A., Matteson, J., Wilson, I. A., Balch, W. E. Crystallization and preliminary crystallographic data for rab guanine-nucleotide dissociation inhibitor (rabgdi) from bovine brain Journal of Molecular Biology 1994 244:469-473 DOI:10.1006/jmbi.1994.1744 PMID:7990134
- Haynes, M. R., Stura, E. A., Hilvert, D., Wilson, I. A. Crystallization and preliminary structural studies of a chorismate mutase catalytic antibody complexed with a transition-state analog Proteins-Structure Function and Genetics 1994 18:198-200 DOI:10.1002/prot.340180211 PMID:8159668
- Wilson, I. A., Stanfield, R. L., Jewell, D. A., Ghiara, J. B., Fremont, D. H., Stura, E. A. Immune recognition of viral-antigens Infectious Agents and Disease-Reviews Issues and Commentary 1994 3:155-162 PMID:7812653
- Stura, E. A., Satterthwait, A. C., Calvo, J. C., Kaslow, D. C., Wilson, I. A. Reverse screening Acta Crystallographica Section D-Biological Crystallography 1994 50:448-455 DOI:10.1107/s0907444994001794 PMID:15299400
- Haynes, M. R., Stura, E. A., Hilvert, D., Wilson, I. A. Routes to catalysis - structure of a catalytic antibody and comparison with its natural counterpart Science 1994 263:646-652 DOI:10.1126/science.8303271 PMID:8303271
- Arevalo, J. H., Hassig, C. A., Stura, E. A., Sims, M. J., Taussig, M. J., Wilson, I. A. Structural-analysis of antibody specificity - detailed comparison of 5 fab'-steroid complexes Journal of Molecular Biology 1994 241:663-690 DOI:10.1006/jmbi.1994.1543 PMID:8071992
- Rini, J. M., Stanfield, R. L., Stura, E. A., Salinas, P. A., Profy, A. T., Wilson, I. A. Crystal-structure of a human-immunodeficiency-virus type-1 neutralizing antibody, 50.1, in complex with its v3 loop peptide antigen Proceedings of the National Academy of Sciences of the United States of America 1993 90:6325-6329 DOI:10.1073/pnas.90.13.6325 PMID:8327513
- Arevalo, J. H., Stura, E. A., Taussig, M. J., Wilson, I. A. Three-dimensional structure of an anti-steroid Fab' and progesterone-Fab' complex Journal of Molecular Biology 1993 231:103-118 DOI:10.1006/jmbi.1993.1260 PMID:8496956
- Chen, P., Schulzegahmen, U., Stura, E. A., Inglese, J., Johnson, D. L., Marolewski, A., Benkovic, S. J., Wilson, I. A. Crystal-structure of glycinamide ribonucleotide transformylase from escherichia-coli at 3.0 Å resolution - a target enzyme for chemotherapy Journal of Molecular Biology 1992 227:283-292 DOI:10.1016/0022-2836(92)90698-j PMID:1522592
- Fremont, D. H., Matsumura, M., Stura, E. A., Peterson, P. A., Wilson, I. A. Crystal-structures of 2 viral peptides in complex with murine mhc class-i h-2k(b) Science 1992 257:919-927 DOI:10.1126/science.1323877 PMID:1323877
- Stura, E. A., Matsumura, M., Fremont, D. H., Saito, Y., Peterson, P. A., Wilson, I. A. Crystallization of murine major histocompatibility complex class-i h-2kb with single peptides Journal of Molecular Biology 1992 228:975-982 DOI:10.1016/0022-2836(92)90881-j PMID:1469730
- Stura, E. A., Chen, P., Wilmot, C. M., Arevalo, J. H., Wilson, I. A. Crystallization studies of glycosylated and unglycosylated human recombinant interleukin-2 Proteins-Structure Function and Genetics 1992 12:24-30 DOI:10.1002/prot.340120104 PMID:1553380
- Stura, E. A., Stanfield, R. L., Fieser, G. G., Silver, S., Roguska, M., Hincapie, L. M., Simmerman, H. K. B., Profy, A. T., Wilson, I. A. Crystallization, sequence, and preliminary crystallographic data for an antipeptide-fab-50.1 and peptide complexes with the principal neutralizing determinant of hiv-1 gp120 Proteins-Structure Function and Genetics 1992 14:499-508 DOI:10.1002/prot.340140410 PMID:1438187
- Ruf, W., Stura, E. A., Lapolla, R. J., Syed, R., Edgington, T. S., Wilson, I. A. Purification, sequence and crystallization of an antitissue factor fab and its use for the crystallization of tissue factor Journal of Crystal Growth 1992 122:253-264 DOI:10.1016/0022-0248(92)90254-g
- Stura, E. A., Nemerow, G. R., Wilson, I. A. Strategies in the crystallization of glycoproteins and protein complexes Journal of Crystal Growth 1992 122:273-285 DOI:10.1016/0022-0248(92)90256-i
- Stura, E. A., Wilson, I. A. Applications of the streak seeding technique in protein crystallization Journal of Crystal Growth 1991 110:270-282 DOI:10.1016/0022-0248(91)90896-d
- Wilson, I. A., Stanfield, R. L., Rini, J. M., Arevalo, J. H., Schulzegahmen, U., Fremont, D. H., Stura, E. A. Structural aspects of antibodies and antibody-antigen complexes Ciba Foundation Symposia 1991 159:13-39 PMID:1959445
- Wilson, I. A., Rini, J. M., Fremont, D. H., Fieser, G. G., Stura, E. A. X-ray crystallographic analysis of free and antigen-complexed fab fragments to investigate structural basis of immune recognition Methods in Enzymology 1991 203:153-176 DOI:10.1016/0076-6879(91)03009-6 PMID:1762555
- Lambert, G., Stura, E. A., Wilson, I. A. Crystallization and preliminary-x-ray diffraction studies of a complex between interleukin-2 and a soluble form of the p55 component of the high-affinity interleukin-2 receptor Journal of Biological Chemistry 1989 264:12730-12736 PMID:2787321
- Stura, E. A., Stanfield, R. L., Fieser, T. M., Balderas, R. S., Smith, L. R., Lerner, R. A., Wilson, I. A. Preliminary crystallographic data and primary sequence for anti-peptide fab' b13i2 and its complex with the c-helix peptide from myohemerythrin Journal of Biological Chemistry 1989 264:15721-15725 PMID:2504725
- Stura, E. A., Johnson, D. L., Inglese, J., Smith, J. M., Benkovic, S. J., Wilson, I. A. Preliminary crystallographic investigations of glycinamide ribonucleotide transformylase Journal of Biological Chemistry 1989 264:9703-9706 PMID:2656702
- Schulzegahmen, U., Rini, J. M., Arevalo, J., Stura, E. A., Kenten, J. H., Wilson, I. A. Preliminary crystallographic data, primary sequence, and binding data for an anti-peptide fab and its complex with a synthetic peptide from influenza-virus hemagglutinin Journal of Biological Chemistry 1988 263:17100-17105 PMID:3182835
- Stura, E. A., Arevalo, J. H., Feinstein, A., Heap, R. B., Taussig, M. J., Wilson, I. A. Analysis of an antiprogesterone antibody - variable crystal morphology of the fab' and steroid fab' complexes Immunology 1987 62:511-521 PMID:3123368 PMCID:PMC1454165