recent publications

• academic article

  • Reyes, V. M., Greasley, S. E., Stura, E. A., Beardsley, G. P., Wilson, I. A. Crystallization and preliminary crystallographic investigations of avian 5-aminoimidazole-4-carboxamide ribonucleotide transformylase-inosine monophosphate cyclohydrolase expressed in escherichia coli Acta Crystallographica Section D-Biological Crystallography  2000 56:1051-1054  DOI:10.1107/s0907444900007800  PMID:10944351
  • Prasad, G. S., Stura, E. A., Elder, J. H., Stout, C. D. Structures of feline immunodeficiency virus dutp pyrophosphatase and its nucleotide complexes in three crystal forms Acta Crystallographica Section D-Biological Crystallography  2000 56:1100-1109  DOI:10.1107/s0907444900009197  PMID:10957629
  • Stanfield, R. L., Cabezas, E., Satterthwait, A. C., Stura, E. A., Profy, A. T., Wilson, I. A. Dual conformations for the hiv-1 gp120 v3 loop in complexes with different neutralizing fabs Structure with Folding & Design  1999 7:131-142  DOI:10.1016/s0969-2126(99)80020-3  PMID:10368281
  • Livnah, O., Johnson, D. L., Stura, E. A., Farrell, F. X., Barbone, F. P., You, Y., Liu, K. D., Goldsmith, M. A., He, W., Krause, C. D., Pestka, S., Jolliffe, L. K., et al. An antagonist peptide epo receptor complex suggests that receptor dimerization is not sufficient for activation Nature Structural Biology  1998 5:993-1004  DOI:10.1038/2965  PMID:9808045
  • Heine, A., Stura, E. A., Yli-Kauhaluoma, J. T., Gao, C., Deng, Q. L., Beno, B. R., Houk, K. N., Janda, K. D., Wilson, I. A. An antibody exo Diels-Alderase inhibitor complex at 1.95 Å resolution Science  1998 279:1934-1940  DOI:10.1126/science.279.5358.1934  PMID:9506943
  • Scott, C. A., Garcia, K. C., Stura, E. A., Peterson, P. A., Wilson, I. A., Teyton, L. Engineering protein for X-ray crystallography: the murine major histocompatibility complex class II molecule I-A(d) Protein Science  1998 7:413-418  DOI:10.1002/pro.5560070222  PMID:9521118  PMCID:PMC2143914
  • Johnson, D. L., Farrell, F. X., Barbone, F. P., McMahon, F. J., Tullai, J., Hoey, K., Livnah, O., Wrighton, N. C., Middleton, S. A., Loughney, D. A., Stura, E. A., Dower, W. J., et al. Identification of a 13 amino acid peptide mimetic of erythropoietin and description of amino acids critical for the mimetic activity of emp1 Biochemistry  1998 37:3699-3710  DOI:10.1021/bi971956y  PMID:9521688
  • Stout, C. D., Stura, E. A., McRee, D. E. Structure of azotobacter vinelandii 7fe ferredoxin at 1.35 Å resolution and determination of the fe-s bonds with 0.01 Å accuracy Journal of Molecular Biology  1998 278:629-639  DOI:10.1006/jmbi.1998.1732  PMID:9600844
  • Huang, M. D., Syed, R., Stura, E. A., Stone, M. J., Stefanko, R. S., Ruf, W., Edgington, T. S., Wilson, I. A. The mechanism of an inhibitory antibody on TF-initiated blood coagulation revealed by the crystal structures of human tissue factor, Fab 5G9 and TF.G9 complex Journal of Molecular Biology  1998 275:873-894  DOI:10.1006/jmbi.1997.1512  PMID:9480775
  • Zeng, Z. H., Castano, A. R., Segelke, B. W., Stura, E. A., Peterson, P. A., Wilson, I. A. Crystal structure of mouse cd1: An mhc-like fold with a large hydrophobic binding groove Science  1997 277:339-345  DOI:10.1126/science.277.5324.339  PMID:9219685
  • Barbas, C. F., Heine, A., Zhong, G. F., Hoffmann, T., Gramatikova, S., Bjornestedt, R., List, B., Anderson, J., Stura, E. A., Wilson, I. A., Lerner, R. A. Immune versus natural selection: Antibody aldolases with enzymic rates but broader scope Science  1997 278:2085-2092  DOI:10.1126/science.278.5346.2085  PMID:9405338
  • He, M., Gani, M., Livnah, O., Stura, E. A., Beale, D., Coley, J., Wilson, I. A., Taussig, M. J. Sequence, specificity and crystallization of an oestrone-3-glucuronide antibody (3910) Immunology  1997 90:632-639  DOI:10.1046/j.1365-2567.1997.00099.x  PMID:9176119
  • Garcia, K. C., Tallquist, M. D., Pease, L. R., Brunmark, A., Scott, C. A., Degano, M., Stura, E. A., Peterson, P. A., Wilson, I. A., Teyton, L. αβ T cell receptor interactions with syngeneic and allogeneic ligands: affinity measurements and crystallization Proceedings of the National Academy of Sciences of the United States of America  1997 94:13838-13843  DOI:10.1073/pnas.94.25.13838  PMID:9391114  PMCID:PMC28394
  • Prasad, G. S., McRee, D. E., Stura, E. A., Levitt, D. G., Lee, H. C., Stout, C. D. Crystal structure of aplysia adp ribosyl cyclase, a homologue of the bifunctional ectozyme cd38 Nature Structural Biology  1996 3:957-964  DOI:10.1038/nsb1196-957  PMID:8901875
  • Prasad, G. S., Stura, E. A., McRee, D. E., Laco, G. S., HasselkusLight, C., Elder, J. H., Stout, C. D. Crystal structure of dutp pyrophosphatase from feline immunodeficiency virus Protein Science  1996 5:2429-2437  DOI:10.1002/pro.5560051205  PMID:8976551  PMCID:PMC2143329
  • Stura, E. A., Ruf, W., Wilson, I. A. Crystallization and preliminary crystallographic data for a ternary complex between tissue factor, factor viia and a bpti-derived inhibitor Journal of Crystal Growth  1996 168:260-269  DOI:10.1016/0022-0248(96)00329-6
  • Livnah, O., Stura, E. A., Johnson, D. L., Middleton, S. A., Mulcahy, L. S., Wrighton, N. C., Dower, W. J., Jolliffe, L. K., Wilson, I. A. Functional mimicry of a protein hormone by a peptide agonist: The epo receptor complex at 2.8 Å Science  1996 273:464-471  DOI:10.1126/science.273.5274.464  PMID:8662530
  • Schalk, I., Zeng, K., Wu, S. K., Stura, E. A., Matteson, J., Huang, M. D., Tandon, A., Wilson, I. A., Balch, W. E. Structure and mutational analysis of Rab GDP-dissociation inhibitor Nature  1996 381:42-48  DOI:10.1038/381042a0  PMID:8609986
  • Fremont, D. H., Stura, E. A., Matsumura, M., Peterson, P. A., Wilson, I. A. Crystal-structure of an h-2k(b)-ovalbumin peptide complex reveals the interplay of primary and secondary anchor positions in the major histocompatibility complex binding groove Proceedings of the National Academy of Sciences of the United States of America  1995 92:2479-2483  DOI:10.1073/pnas.92.7.2479  PMID:7708669
  • Stura, E. A., Ghosh, S., Garciajunceda, E., Chen, L. R., Wong, C. H., Wilson, I. A. Crystallization and preliminary crystallographic data for class-i deoxyribose-5-phosphate aldolase from escherichia-coli - an application of reverse screening Proteins-Structure Function and Genetics  1995 22:67-72  DOI:10.1002/prot.340220110  PMID:7675789
  • Klein, C., Chen, P., Arevalo, J. H., Stura, E. A., Marolewski, A., Warren, M. S., Benkovic, S. J., Wilson, I. A. Towards structure-based drug design - crystal-structure of a multisubstrate adduct complex of glycinamide ribonucleotide transformylase at 1.96 Å resolution Journal of Molecular Biology  1995 249:153-175  DOI:10.1006/jmbi.1995.0286  PMID:7776369
  • Diller, T. C., Shaw, A., Stura, E. A., Vacquier, V. D., Stout, C. D. Acid ph crystallization of the basic protein lysin from the spermatozoa of red abalone (haliotis rufescens) Acta Crystallographica Section D-Biological Crystallography  1994 50:620-626  DOI:10.1107/s0907444993013356  PMID:15299426
  • Churchill, M. E. A., Stura, E. A., Pinilla, C., Appel, J. R., Houghten, R. A., Kono, D. H., Balderas, R. S., Fieser, G. G., Schulzegahmen, U., Wilson, I. A. Crystal-structure of a peptide complex of antiinfluenza peptide antibody-Fab-26/9 - comparison of 2 different antibodies bound to the same peptide antigen Journal of Molecular Biology  1994 241:534-556  DOI:10.1006/jmbi.1994.1530  PMID:7520084
  • Ghiara, J. B., Stura, E. A., Stanfield, R. L., Profy, A. T., Wilson, I. A. Crystal-structure of the principal neutralization site of hiv-1 Science  1994 264:82-85  DOI:10.1126/science.7511253  PMID:7511253
  • Schalk, I. J., Stura, E. A., Matteson, J., Wilson, I. A., Balch, W. E. Crystallization and preliminary crystallographic data for rab guanine-nucleotide dissociation inhibitor (rabgdi) from bovine brain Journal of Molecular Biology  1994 244:469-473  DOI:10.1006/jmbi.1994.1744  PMID:7990134
  • Haynes, M. R., Stura, E. A., Hilvert, D., Wilson, I. A. Crystallization and preliminary structural studies of a chorismate mutase catalytic antibody complexed with a transition-state analog Proteins-Structure Function and Genetics  1994 18:198-200  DOI:10.1002/prot.340180211  PMID:8159668
  • Wilson, I. A., Stanfield, R. L., Jewell, D. A., Ghiara, J. B., Fremont, D. H., Stura, E. A. Immune recognition of viral-antigens Infectious Agents and Disease-Reviews Issues and Commentary  1994 3:155-162  PMID:7812653
  • Stura, E. A., Satterthwait, A. C., Calvo, J. C., Kaslow, D. C., Wilson, I. A. Reverse screening Acta Crystallographica Section D-Biological Crystallography  1994 50:448-455  DOI:10.1107/s0907444994001794  PMID:15299400
  • Haynes, M. R., Stura, E. A., Hilvert, D., Wilson, I. A. Routes to catalysis - structure of a catalytic antibody and comparison with its natural counterpart Science  1994 263:646-652  DOI:10.1126/science.8303271  PMID:8303271
  • Arevalo, J. H., Hassig, C. A., Stura, E. A., Sims, M. J., Taussig, M. J., Wilson, I. A. Structural-analysis of antibody specificity - detailed comparison of 5 fab'-steroid complexes Journal of Molecular Biology  1994 241:663-690  DOI:10.1006/jmbi.1994.1543  PMID:8071992
  • Rini, J. M., Stanfield, R. L., Stura, E. A., Salinas, P. A., Profy, A. T., Wilson, I. A. Crystal-structure of a human-immunodeficiency-virus type-1 neutralizing antibody, 50.1, in complex with its v3 loop peptide antigen Proceedings of the National Academy of Sciences of the United States of America  1993 90:6325-6329  DOI:10.1073/pnas.90.13.6325  PMID:8327513
  • Arevalo, J. H., Stura, E. A., Taussig, M. J., Wilson, I. A. Three-dimensional structure of an anti-steroid Fab' and progesterone-Fab' complex Journal of Molecular Biology  1993 231:103-118  DOI:10.1006/jmbi.1993.1260  PMID:8496956
  • Chen, P., Schulzegahmen, U., Stura, E. A., Inglese, J., Johnson, D. L., Marolewski, A., Benkovic, S. J., Wilson, I. A. Crystal-structure of glycinamide ribonucleotide transformylase from escherichia-coli at 3.0 Å resolution - a target enzyme for chemotherapy Journal of Molecular Biology  1992 227:283-292  DOI:10.1016/0022-2836(92)90698-j  PMID:1522592
  • Fremont, D. H., Matsumura, M., Stura, E. A., Peterson, P. A., Wilson, I. A. Crystal-structures of 2 viral peptides in complex with murine mhc class-i h-2k(b) Science  1992 257:919-927  DOI:10.1126/science.1323877  PMID:1323877
  • Stura, E. A., Matsumura, M., Fremont, D. H., Saito, Y., Peterson, P. A., Wilson, I. A. Crystallization of murine major histocompatibility complex class-i h-2kb with single peptides Journal of Molecular Biology  1992 228:975-982  DOI:10.1016/0022-2836(92)90881-j  PMID:1469730
  • Stura, E. A., Chen, P., Wilmot, C. M., Arevalo, J. H., Wilson, I. A. Crystallization studies of glycosylated and unglycosylated human recombinant interleukin-2 Proteins-Structure Function and Genetics  1992 12:24-30  DOI:10.1002/prot.340120104  PMID:1553380
  • Stura, E. A., Stanfield, R. L., Fieser, G. G., Silver, S., Roguska, M., Hincapie, L. M., Simmerman, H. K. B., Profy, A. T., Wilson, I. A. Crystallization, sequence, and preliminary crystallographic data for an antipeptide-fab-50.1 and peptide complexes with the principal neutralizing determinant of hiv-1 gp120 Proteins-Structure Function and Genetics  1992 14:499-508  DOI:10.1002/prot.340140410  PMID:1438187
  • Ruf, W., Stura, E. A., Lapolla, R. J., Syed, R., Edgington, T. S., Wilson, I. A. Purification, sequence and crystallization of an antitissue factor fab and its use for the crystallization of tissue factor Journal of Crystal Growth  1992 122:253-264  DOI:10.1016/0022-0248(92)90254-g
  • Stura, E. A., Nemerow, G. R., Wilson, I. A. Strategies in the crystallization of glycoproteins and protein complexes Journal of Crystal Growth  1992 122:273-285  DOI:10.1016/0022-0248(92)90256-i
  • Stura, E. A., Wilson, I. A. Applications of the streak seeding technique in protein crystallization Journal of Crystal Growth  1991 110:270-282  DOI:10.1016/0022-0248(91)90896-d
  • Wilson, I. A., Stanfield, R. L., Rini, J. M., Arevalo, J. H., Schulzegahmen, U., Fremont, D. H., Stura, E. A. Structural aspects of antibodies and antibody-antigen complexes Ciba Foundation Symposia  1991 159:13-39  PMID:1959445
  • Wilson, I. A., Rini, J. M., Fremont, D. H., Fieser, G. G., Stura, E. A. X-ray crystallographic analysis of free and antigen-complexed fab fragments to investigate structural basis of immune recognition Methods in Enzymology  1991 203:153-176  DOI:10.1016/0076-6879(91)03009-6  PMID:1762555
  • Lambert, G., Stura, E. A., Wilson, I. A. Crystallization and preliminary-x-ray diffraction studies of a complex between interleukin-2 and a soluble form of the p55 component of the high-affinity interleukin-2 receptor Journal of Biological Chemistry  1989 264:12730-12736  PMID:2787321
  • Stura, E. A., Stanfield, R. L., Fieser, T. M., Balderas, R. S., Smith, L. R., Lerner, R. A., Wilson, I. A. Preliminary crystallographic data and primary sequence for anti-peptide fab' b13i2 and its complex with the c-helix peptide from myohemerythrin Journal of Biological Chemistry  1989 264:15721-15725  PMID:2504725
  • Stura, E. A., Johnson, D. L., Inglese, J., Smith, J. M., Benkovic, S. J., Wilson, I. A. Preliminary crystallographic investigations of glycinamide ribonucleotide transformylase Journal of Biological Chemistry  1989 264:9703-9706  PMID:2656702
  • Schulzegahmen, U., Rini, J. M., Arevalo, J., Stura, E. A., Kenten, J. H., Wilson, I. A. Preliminary crystallographic data, primary sequence, and binding data for an anti-peptide fab and its complex with a synthetic peptide from influenza-virus hemagglutinin Journal of Biological Chemistry  1988 263:17100-17105  PMID:3182835
  • Stura, E. A., Arevalo, J. H., Feinstein, A., Heap, R. B., Taussig, M. J., Wilson, I. A. Analysis of an antiprogesterone antibody - variable crystal morphology of the fab' and steroid fab' complexes Immunology  1987 62:511-521  PMID:3123368  PMCID:PMC1454165