recent publications

• academic article

  • Pedro-Rosa, L., Buckner, F. S., Ranade, R. M., Eberhart, C., Madoux, F., Gillespie, J. R., Koh, C. Y., Brown, S., Lohse, J., Verlinde, C. L. M., Fan, E., Bannister, T., et al. Identification of potent inhibitors of the Trypanosoma brucei methionyl-tRNA synthetase via high-throughput orthogonal screening Journal of Biomolecular Screening  2015 20:122-130  DOI:10.1177/1087057114548832  PMID:25163684  PMCID:PMC4378865
  • Izard, T., Aevarsson, A., Allen, M. D., Westphal, A. H., Perham, R. N., de Kok, A., Hol, W. G. J. Principles of quasi-equivalence and Euclidean geometry govern the assembly of cubic and dodecahedral cores of pyruvate dehydrogenase complexes Proceedings of the National Academy of Sciences of the United States of America  1999 96:1240-1245  DOI:10.1073/pnas.96.4.1240  PMID:9990008
  • Bernstein, B. E., Williams, D. M., Bressi, J. C., Kuhn, P., Gelb, M. H., Blackburn, G. M., Hol, W. G. J. A bisubstrate analog induces unexpected conformational changes in phosphoglycerate kinase from trypanosoma brucei Journal of Molecular Biology  1998 279:1137-1148  DOI:10.1006/jmbi.1998.1835  PMID:9642090
  • Redinbo, M. R., Stewart, L., Kuhn, P., Champoux, J. J., Hol, W. G. J. Crystal structures of human topoisomerase i in covalent and noncovalent complexes with DNA Science  1998 279:1504-1513  DOI:10.1126/science.279.5356.1504  PMID:9488644
  • Izard, T., Sarfaty, S., Westphal, A., DeKok, A., Hol, W. G. J. Improvement of diffraction quality upon rehydration of dehydrated icosahedral Enterococcus faecalis pyruvate dehydrogenase core crystals Protein Science  1997 6:913-915  DOI:10.1002/pro.5560060419  PMID:9098902  PMCID:PMC2144755