recent publications
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academic article
- Pedro-Rosa, L., Buckner, F. S., Ranade, R. M., Eberhart, C., Madoux, F., Gillespie, J. R., Koh, C. Y., Brown, S., Lohse, J., Verlinde, C. L. M., Fan, E., Bannister, T., et al. Identification of potent inhibitors of the Trypanosoma brucei methionyl-tRNA synthetase via high-throughput orthogonal screening Journal of Biomolecular Screening 2015 20:122-130 DOI:10.1177/1087057114548832 PMID:25163684 PMCID:PMC4378865
- Izard, T., Aevarsson, A., Allen, M. D., Westphal, A. H., Perham, R. N., de Kok, A., Hol, W. G. J. Principles of quasi-equivalence and Euclidean geometry govern the assembly of cubic and dodecahedral cores of pyruvate dehydrogenase complexes Proceedings of the National Academy of Sciences of the United States of America 1999 96:1240-1245 DOI:10.1073/pnas.96.4.1240 PMID:9990008
- Bernstein, B. E., Williams, D. M., Bressi, J. C., Kuhn, P., Gelb, M. H., Blackburn, G. M., Hol, W. G. J. A bisubstrate analog induces unexpected conformational changes in phosphoglycerate kinase from trypanosoma brucei Journal of Molecular Biology 1998 279:1137-1148 DOI:10.1006/jmbi.1998.1835 PMID:9642090
- Redinbo, M. R., Stewart, L., Kuhn, P., Champoux, J. J., Hol, W. G. J. Crystal structures of human topoisomerase i in covalent and noncovalent complexes with DNA Science 1998 279:1504-1513 DOI:10.1126/science.279.5356.1504 PMID:9488644
- Izard, T., Sarfaty, S., Westphal, A., DeKok, A., Hol, W. G. J. Improvement of diffraction quality upon rehydration of dehydrated icosahedral Enterococcus faecalis pyruvate dehydrogenase core crystals Protein Science 1997 6:913-915 DOI:10.1002/pro.5560060419 PMID:9098902 PMCID:PMC2144755