recent publications

• academic article

  • Mazzucato, M., Cozzi, M. R., Battiston, M., Jandrot-Perrus, M., Mongiat, M., Marchese, P., Kunicki, T. J., Ruggeri, Z. M., De Marco, L. Distinct spatio-temporal Ca(2+) signaling elicited by integrin alpha 2 beta 1 and glycoprotein VI under flow Blood  2009 114:2793-2801  DOI:10.1182/blood-2008-12-193490  PMID:19622836  PMCID:PMC2756134
  • Mazzucato, M., Cozzi, M. R., Pradella, P., Ruggeri, Z. M., De Marco, L. Distinct roles of ADP receptors in von Willebrand factor-mediated platelet signaling and activation under high flow Blood  2004 104:3221-3227  DOI:10.1182/blood-2004-03-1145  PMID:15284110
  • Kasirer-Friede, A., Cozzi, M. R., Mazzucato, M., De Marco, L., Ruggeri, Z. M., Shattil, S. J. Signaling through GP Ib-IX-V activates alpha IIb beta 3 independently of other receptors Blood  2004 103:3403-3411  DOI:10.1182/blood-2003-10-3664  PMID:14726383
  • Mazzucato, M., Pradella, P., Cozzi, M. R., De Marco, L., Ruggeri, Z. M. Sequential cytoplasmic calcium signals in a 2-stage platelet activation process induced by the glycoprotein Ib alpha mechanoreceptor Blood  2002 100:2793-2800  DOI:10.1182/blood-2002-02-0514  PMID:12351387
  • Mazzucato, M., De Marco, L., Masotti, A., Pradella, P., Bahou, W. F., Ruggeri, Z. M. Characterization of the initial alpha-thrombin interaction with glycoprotein Ib alpha in relation to platelet activation Journal of Biological Chemistry  1998 273:1880-1887  DOI:10.1074/jbc.273.4.1880  PMID:9442020
  • Marchese, P., Murata, M., Mazzucato, M., Pradella, P., Demarco, L., Ware, J., Ruggeri, Z. M. Identification of three tyrosine residues of glycoprotein Ib alpha with distinct roles in von Willebrand factor and alpha-thrombin binding Journal of Biological Chemistry  1995 270:9571-9578  PMID:7721887
  • Demarco, L., Mazzucato, M., Masotti, A., Ruggeri, Z. M. Localization and characterization of an alpha-thrombin-binding site on platelet glycoprotein Ib alpha Journal of Biological Chemistry  1994 269:6478-6484  PMID:8119999
  • Ware, J., Russell, S. R., Marchese, P., Murata, M., Mazzucato, M., Demarco, L., Ruggeri, Z. M. Point mutation in a leucine-rich repeat of platelet glycoprotein Ib alpha resulting in the Bernard-Soulier syndrome Journal of Clinical Investigation  1993 92:1213-1220  DOI:10.1172/jci116692  PMID:7690774  PMCID:PMC288260
  • Demarco, L., Mazzucato, M., Masotti, A., Fenton, J. W., Ruggeri, Z. M. Function of glycoprotein Ib alpha in platelet activation induced by alpha-thrombin Journal of Biological Chemistry  1991 266:23776-23783  PMID:1748654
  • Demarco, L., Mazzucato, M., Fabris, F., Deroia, D., Coser, P., Girolami, A., Vicente, V., Ruggeri, Z. M. Variant Bernard-Soulier syndrome type bolzano. A congenital bleeding disorder due to a structural and functional abnormality of the platelet glycoprotein Ib-IX complex Journal of Clinical Investigation  1990 86:25-31  DOI:10.1172/jci114692  PMID:1694864  PMCID:PMC296685
  • Demarco, L., Mazzucato, M., Deroia, D., Casonato, A., Federici, A. B., Girolami, A., Ruggeri, Z. M. Distinct abnormalities in the interaction of purified types IIA and IIB von Willebrand factor with the two platelet binding sites, glycoprotein complexes Ib-IX and IIb-IIIa Journal of Clinical Investigation  1990 86:785-792  DOI:10.1172/jci114775  PMID:2394830  PMCID:PMC296793
  • Casonato, A., Demarco, L., Mazzucato, M., Deangelis, V., Deroia, D., Fabris, F., Ruggeri, Z. M., Girolami, A. A new congenital platelet abnormality characterized by spontaneous platelet aggregation, enhanced von Willebrand factor platelet interaction, and the presence of all von Willebrand factor multimers in plasma Blood  1989 74:2028-2033  PMID:2804346