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Refined crystallographic structure of pseudomonas aeruginosa exotoxin a and its implications for the molecular mechanism of toxicity

Academic Article
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  • Research
  • Identity
  • Additional Document Info
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Overview

authors

  • Wedekind, J. E.
  • Trame, C. B.
  • Dorywalska, M.
  • Koehl, P.
  • Raschke, T. M.
  • McKee, M.
  • FitzGerald, D.
  • Collier, R. J.
  • McKay, Dianne

publication date

  • December 2001

journal

  • Journal of Molecular Biology  Journal

subject areas

  • ADP Ribose Transferases
  • Amino Acid Sequence
  • Bacterial Toxins
  • Binding Sites
  • Computer Simulation
  • Crystallization
  • Crystallography, X-Ray
  • Exotoxins
  • Furin
  • Hydrogen Bonding
  • Hydrogen-Ion Concentration
  • Ligands
  • Models, Molecular
  • Mutation
  • Pliability
  • Protein Structure, Secondary
  • Protein Structure, Tertiary
  • Pseudomonas aeruginosa
  • Sequence Alignment
  • Static Electricity
  • Structure-Activity Relationship
  • Subtilisins
  • Virulence Factors
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Research

keywords

  • Pseudomonas aeruginosa toxicity
  • crystal structure
  • exotoxin
  • furin
  • pH-induced conformational change
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Identity

International Standard Serial Number (ISSN)

  • 0022-2836

Digital Object Identifier (DOI)

  • 10.1006/jmbi.2001.5195

PubMed ID

  • 11734000
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Additional Document Info

start page

  • 823

end page

  • 837

volume

  • 314

issue

  • 4

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