recent publications

• academic article

  • Liu, Y., Goswami, R. K., Liu, C., Sinha, S. C. Chemically programmed bispecific antibody targeting legumain protease and avß3 integrin mediates strong antitumor effects Molecular Pharmaceutics  2015 12:2544-2550  DOI:10.1021/acs.molpharmaceut.5b00257  PMID:26024761
  • Goswami, R. K., Liu, Y., Liu, C., Lerner, R. A., Sinha, S. C. Synthesis and evaluation of the aldolase antibody-derived chemical-antibodies targeting α5β1 integrin Molecular Pharmaceutics  2013 10:538-543  DOI:10.1021/mp3004463  PMID:23102054  PMCID:PMC3596504
  • Goswami, R. K., Bajjuri, K. M., Forsyth, J. S., Das, S., Hassenpflug, W., Huang, Z. Z., Lerner, R. A., Felding-Habermann, B., Sinhe, S. C. Chemically programmed antibodies targeting multiple alpha(v) integrins and their effects on tumor-related functions in vitro Bioconjugate Chemistry  2011 22:1535-1544  DOI:10.1021/bc2000879  PMID:21774545  PMCID:PMC3277862
  • Gavrilyuk, J. I., Wuellner, U., Salahuddin, S., Goswami, R. K., Sinha, S. C., Barbas, C. F. An efficient chemical approach to bispecific antibodies and antibodies of high valency Bioorganic & Medicinal Chemistry Letters  2009 19:3716-3720  DOI:10.1016/j.bmcl.2009.05.047  PMID:19497743  PMCID:PMC2743550
  • Goswami, R. K., Huang, Z. Z., Forsyth, J. S., Felding-Habermann, B., Sinha, S. C. Multiple catalytic aldolase antibodies suitable for chemical programming Bioorganic & Medicinal Chemistry Letters  2009 19:3821-3824  DOI:10.1016/j.bmcl.2009.04.041  PMID:19428247  PMCID:PMC2923540