recent publications
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academic article
- Liu, Y., Goswami, R. K., Liu, C., Sinha, S. C. Chemically programmed bispecific antibody targeting legumain protease and avß3 integrin mediates strong antitumor effects Molecular Pharmaceutics 2015 12:2544-2550 DOI:10.1021/acs.molpharmaceut.5b00257 PMID:26024761
- Goswami, R. K., Liu, Y., Liu, C., Lerner, R. A., Sinha, S. C. Synthesis and evaluation of the aldolase antibody-derived chemical-antibodies targeting α5β1 integrin Molecular Pharmaceutics 2013 10:538-543 DOI:10.1021/mp3004463 PMID:23102054 PMCID:PMC3596504
- Goswami, R. K., Bajjuri, K. M., Forsyth, J. S., Das, S., Hassenpflug, W., Huang, Z. Z., Lerner, R. A., Felding-Habermann, B., Sinhe, S. C. Chemically programmed antibodies targeting multiple alpha(v) integrins and their effects on tumor-related functions in vitro Bioconjugate Chemistry 2011 22:1535-1544 DOI:10.1021/bc2000879 PMID:21774545 PMCID:PMC3277862
- Gavrilyuk, J. I., Wuellner, U., Salahuddin, S., Goswami, R. K., Sinha, S. C., Barbas, C. F. An efficient chemical approach to bispecific antibodies and antibodies of high valency Bioorganic & Medicinal Chemistry Letters 2009 19:3716-3720 DOI:10.1016/j.bmcl.2009.05.047 PMID:19497743 PMCID:PMC2743550
- Goswami, R. K., Huang, Z. Z., Forsyth, J. S., Felding-Habermann, B., Sinha, S. C. Multiple catalytic aldolase antibodies suitable for chemical programming Bioorganic & Medicinal Chemistry Letters 2009 19:3821-3824 DOI:10.1016/j.bmcl.2009.04.041 PMID:19428247 PMCID:PMC2923540