recent publications

• academic article

  • Savas, J. N., Ribeiro, L. F., Wierda, K. D., Wright, R., DeNardo-Wilke, L. A., Rice, H. C., Chamma, I., Wang, Y. Z., Zemla, R., Lavallee-Adam, M., Vennekens, K. M., O'Sullivan, M. L., et al. The sorting receptor SorCS1 regulates trafficking of neurexin and AMPA receptors Neuron  2015 87:764-780  DOI:10.1016/j.neuron.2015.08.007  PMID:26291160  PMCID:PMC4692362
  • de Wit, J., O'Sullivan, M. L., Savas, J. N., Condomitti, G., Caccese, M. C., Vennekens, K. M., Yates, J. R., Ghosh, A. Unbiased discovery of glypican as a receptor for LRRTM4 in regulating excitatory synapse development Neuron  2013 79:696-711  DOI:10.1016/j.neuron.2013.06.049  PMID:23911103  PMCID:PMC4003527
  • O'Sullivan, M. L., de Wit, J., Savas, J. N., Comoletti, D., Otto-Hitt, S., Yates III, J. R., Ghosh, A. FLRT proteins are endogenous latrophilin ligands and regulate excitatory synapse development Neuron  2012 73:903-910  DOI:10.1016/j.neuron.2012.01.018  PMID:22405201  PMCID:PMC3326387
  • de Wit, J., Sylwestrak, E., O'Sullivan, M. L., Otto, S., Tiglio, K., Savas, J. N., Yates, J. R., Comoletti, D., Taylor, P., Ghosh, A. LRRTM2 interacts with Neurexin1 and regulates excitatory synapse formation Neuron  2009 64:799-806  DOI:10.1016/j.neuron.2009.12.019  PMID:20064388  PMCID:PMC2829666
  • van der Pluijm, I., Garinis, G. A., Brandt, R. M. C., Gorgels, Tgmf, Wijnhoven, S. W., Diderich, K. E. M., de Wit, J., Mitchell, J. R., van Oostrom, C., Beems, R., Niedernhofer, L. J., Velasco, S., et al. Impaired genome maintenance suppresses the growth hormone-insulin-like growth factor 1 axis in mice with cockayne syndrome PLoS Biology  2007 5:23-38  DOI:10.1371/journal.pbio.0050002  PMID:17326724  PMCID:PMC1698505
  • Niedernhofer, L. J., Odijk, H., Budzowska, M., van Drunen, E., Maas, A., Theil, A. F., de Wit, J., Jaspers, N. G. J., Beverloo, H. B., Hoeijmakers, J. H. J., Kanaar, R. The structure-specific endonuclease ercc1-xpf is required to resolve DNA interstrand cross-link-induced double-strand breaks Molecular and Cellular Biology  2004 24:5776-5787  DOI:10.1128/mcb.24.13.5776-5787.2004  PMID:15199134
  • Niedernhofer, L. J., Essers, J., Weeda, G., Beverloo, B., de Wit, J., Muijtjens, M., Odijk, H., Hoeijmakers, J. H. J., Kanaar, R. The structure-specific endonuclease ercc1-xpf is required for targeted gene replacement in embryonic stem cells EMBO Journal  2001 20:6540-6549  DOI:10.1093/emboj/20.22.6540  PMID:11707424  PMCID:PMC125716