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Journal of the American Chemical Society

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articles

  • Enhancement of a Heroin Vaccine through Hapten Deuteration.  142:13294-13298. 2020
  • Pd(II)-Catalyzed Enantioselective γ-C(sp 3)-H Functionalizations of Free Cyclopropylmethylamines.  142:12015-12019. 2020
  • Synthesis of (-)-Picrotoxinin by Late-Stage Strong Bond Activation.  142:11376-11381. 2020
  • Semisynthesis of a Bacterium with Non-canonical Cell-Wall Cross-Links.  142:10910-10913. 2020
  • Sulfur(VI) Fluoride Exchange (SuFEx)-Enabled High-Throughput Medicinal Chemistry.  142:10899-10904. 2020
  • Achieving Site-Selectivity for C-H Activation Processes Based on Distance and Geometry: A Carpenter's Approach.  142:10571-10591. 2020
  • Catalytic α-Hydroarylation of Acrylates and Acrylamides via an Interrupted Hydrodehalogenation Reaction.  142:10477-10484. 2020
  • Two-Phase Synthesis of Taxol.  142:10526-10533. 2020
  • 2-Sulfonylpyridines as Tunable, Cysteine-Reactive Electrophiles.  142:8972-8979. 2020
  • Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect Splicing.  142:8706-8727. 2020
  • Total Synthesis of (-)-Maximiscin.  142:8608-8613. 2020
  • Targeted Degradation of the Oncogenic MicroRNA 17-92 Cluster by Structure-Targeting Ligands.  142:6970-6982. 2020
  • Ligand-Enabled Monoselective β-C(sp 3)-H Acyloxylation of Free Carboxylic Acids Using a Practical Oxidant.  142:6769-6776. 2020
  • Chalcogen Bonding and Hydrophobic Effects Force Molecules into Small Spaces.  142:5876-5883. 2020
  • Enantiodivergent Formation of C-P Bonds: Synthesis of P-Chiral Phosphines and Methylphosphonate Oligonucleotides.  142:5785-5792. 2020
  • Iridium(I)-Catalyzed α-C(sp 3)-H Alkylation of Saturated Azacycles.  142:5117-5125. 2020
  • Trisaccharide Sulfate and Its Sulfonamide as an Effective Substrate and Inhibitor of Human Endo-O-sulfatase-1.  142:5282-5292. 2020
  • Isotopically directed symmetry breaking and enantioenrichment in attrition-enhanced deracemization.  142:3873-3879. 2020
  • δ-C-H mono- and dihalogenation of alcohols.  142:2766-2770. 2020
  • Nanopore sequencing of an expanded genetic alphabet reveals high-fidelity replication of a predominantly hydrophobic unnatural base pair.  142:2110-2114. 2020
  • Radical reactions in cavitands unveil the effects of affinity on dynamic supramolecular systems.  142:2396-2403. 2020
  • Selection of aptamers with large hydrophobic 2'-substituents.  142:2125-2128. 2020
  • Next-Generation Total Synthesis of Vancomycin.  142:16039-16050. 2020
  • Palladium-Catalyzed 3+2 Cycloaddition via Twofold 1,3-C(sp(3))-H Activation.  142:16552-16556. 2020
  • Serine-Selective Bioconjugation.  142:17236-17242. 2020
  • Total Synthesis of Tagetitoxin.  142:13683-13688. 2020
  • Progress toward eukaryotic semisynthetic organisms: translation of unnatural codons.  141:20166-20170. 2019
  • Total synthesis and stereochemical assignment of streptide.  141:17361-17369. 2019
  • Understanding the activity and enantioselectivity of acetyl-protected aminoethyl quinoline ligands in palladium-catalyzed β-C(sp3)-H bond arylation reactions.  141:16726-16733. 2019
  • Coupling of DNA circuit and templated reactions for quadratic amplification and release of functional molecules.  141:16288-16295. 2019
  • Hemilabile benzyl ether enables γ-C(sp3)-H carbonylation and olefination of alcohols.  141:15494-15497. 2019
  • Catalytic deuterium incorporation within metabolically stable β-amino C-H bonds of drug molecules.  141:14570-14575. 2019
  • Single-atom fluorescence switch: a general approach toward visible-light-activated dyes for biological imaging.  141:14699-14706. 2019
  • meta C-H arylation of electron-rich arenes: reversing the conventional site selectivity.  141:14870-14877. 2019
  • A sulfonamide sialoside analogue for targeting siglec-8 and -F on immune cells.  141:14032-14037. 2019
  • Consequence of hapten stereochemistry: an efficacious methamphetamine vaccine.  141:14089-14092. 2019
  • O-GlcNAc engineering of GPCR peptide-agonists improves their stability and in vivo activity.  141:14210-14219. 2019
  • Triarylaminium radical cation promoted coupling of catharanthine with vindoline: diastereospecific synthesis of anhydrovinblastine and reaction scope.  141:14349-14355. 2019
  • Asymmetric total synthesis of arcutinidine, arcutinine, and arcutine.  141:13718-13723. 2019
  • Toward a synthetic yeast endosymbiont with a minimal genome.  141:13799-13802. 2019
  • The role of protein thermodynamics and primary structure in fibrillogenesis of variable domains from immunoglobulin light chains.  141:13562-13571. 2019
  • Impact of stereo- and regiochemistry on energetic materials.  141:12531-12535. 2019
  • Characterization and crystal structure of a nonheme diiron monooxygenase involved in platensimycin and platencin biosynthesis.  141:12406-12412. 2019
  • Enantioselective synthesis of α-allyl amino esters via hydrogen-bond-donor catalysis.  141:11414-11419. 2019
  • Programmable artificial cells using histamine-responsive synthetic riboswitch.  141:11103-11114. 2019
  • Controlled cationic polymerization: single-component initiation under ambient conditions.  141:10605-10609. 2019
  • Optimization of replication, transcription, and translation in a semi-synthetic organism.  141:10644-10653. 2019
  • An efficient modular one-pot synthesis of heparin-based anticoagulant idraparinux.  141:10309-10314. 2019
  • Monoclonal antibodies for combating synthetic opioid intoxication.  141:10489-10503. 2019
  • Synthesis of (+/-)-idarubicinone via global functionalization of tetracene.  141:10193-10198. 2019
  • Expanding reactivity in DNA-encoded library synthesis via reversible binding of DNA to an inert quaternary ammonium support.  141:9998-10006. 2019
  • Chemo-, regio-, diastereo-, and enantioselective palladium allylic alkylation of 1,3-dioxaboroles as synthetic equivalents of α-hydroxyketones.  141:9521-9526. 2019
  • A chlorine-atom-controlled terminal-epoxide-initiated bicyclization cascade enables a synthesis of the potent cytotoxins haterumaimides J and K.  141:9202-9206. 2019
  • Direct intermolecular anti-Markovnikov hydroazidation of unactivated olefins.  141:9415-9421. 2019
  • Total synthesis of (+)-granatumine A and related bislactone limonoid alkaloids via a pyran to pyridine interconversion.  141:9191-9196. 2019
  • Discovery of FAHFA-containing triacylglycerols and their metabolic regulation.  141:8798-8806. 2019
  • Ipomoeassin F binds Sec61α to inhibit protein translocation.  141:8450-8461. 2019
  • Convergent total synthesis of principinol D, a rearranged kaurane diterpenoid.  141:8088-8092. 2019
  • General synthetic approach for the Laurencia family of natural products empowered by a potentially biomimetic ring expansion.  141:7776-7788. 2019
  • Hydroalkylation of olefins to form quaternary carbons.  141:7709-7714. 2019
  • Total synthesis of (+)-arborisidine.  141:7715-7720. 2019
  • Targeting RNA with small molecules to capture opportunities at the intersection of chemistry, biology, and medicine.  141:6776-6790. 2019
  • A radical approach to anionic chemistry: synthesis of ketones, alcohols, and amines.  141:6726-6739. 2019
  • Synthesis of sialidase-resistant oligosaccharide and antibody glycoform containing α2,6-linked 3Fax-Neu5Ac.  141:6484-6488. 2019
  • Electrochemically driven, Ni-catalyzed aryl amination: scope, mechanism, and applications.  141:6392-6402. 2019
  • Identification of the Formycin A biosynthetic gene cluster from streptomyces kaniharaensis illustrates the interplay between biological pyrazolopyrimidine formation and de novo purine biosynthesis.  141:6127-6131. 2019
  • Allyl-nickel catalysis enables carbonyl dehydrogenation and oxidative cycloalkenylation of ketones.  141:5669-5674. 2019
  • The total synthesis of chalcitrin.  141:4515-4520. 2019
  • Analysis of protein-protein interaction in a single live cell by using a FRET system based on genetic code expansion technology.  141:4273-4281. 2019
  • Enantioselective Conia-ene-type cyclizations of alkynyl ketones through cooperative action of B(C6F5)(3), N-alkylamine and a Zn-based catalyst.  141:4199-4203. 2019
  • Cryptic and stereospecific hydroxylation, oxidation, and reduction in platensimycin and platencin biosynthesis.  141:4043-4050. 2019
  • Oligosaccharide synthesis and translational innovation.  141:3735-3754. 2019
  • Natural products in the "marketplace": Interfacing synthesis and biology.  141:3332-3346. 2019
  • Nickel-catalyzed enantioselective hydroarylation and hydroalkenylation of styrenes.  141:3395-3399. 2019
  • A designed small molecule inhibitor of a non-coding RNA sensitizes HER2 negative cancers to herceptin.  141:2960-2974. 2019
  • Development of a terpene feedstock-based oxidative synthetic approach to the illicium sesquiterpenes.  141:3083-3099. 2019
  • Enantioselective synthesis of azamerone.  141:2867-2871. 2019
  • Chemical interventions for the opioid crisis: key advances and remaining challenges.  141:1798-1806. 2019
  • Sequential functionalization of meta-C-H and ipso-C-O bonds of phenols.  141:1903-1907. 2019
  • 11-step total synthesis of teleocidins B-1-6-4.  141:1494-1497. 2019
  • Total synthesis of paspaline A and emindole PB enabled by computational augmentation of a transform-guided retrosynthetic strategy.  141:1479-1483. 2019
  • Direct carbon isotope exchange through decarboxylative carboxylation.  141:774-779. 2019
  • Benzimidazoles as metal-free and recyclable hydrides for CO2 reduction to formate.  141:272-280. 2019
  • Concise total synthesis of herqulines B and C.  141:29-32. 2019
  • Enantioselective synthesis of isocarbostyril alkaloids and analogs using catalytic dearomative functionalization of benzene.  141:657-670. 2019
  • Palladium-catalyzed dearomative syn-1,4-diamination.  141:163-167. 2019
  • Rh(III)-catalyzed meta-C-H alkenylation with alkynes.  141:76-79. 2019
  • Nickel-catalyzed 1,2-diarylation of simple alkenyl amides.  140:17878-17883. 2018
  • Overcoming the limitations of γ, and δ-C-H arylation of amines through ligand development.  140:17884-17894. 2018
  • Total synthesis, biological evaluation, and target identification of rare Abies sesquiterpenoids.  140:17465-17473. 2018
  • Branch-selective addition of unactivated olefins into imines and aldehydes.  140:16976-16981. 2018
  • Discovery and characterization of 1-aminocyclopropane-1-carboxylic acid synthase of bacterial origin.  140:16957-16961. 2018
  • Engineering improved antiphosphotyrosine antibodies based on an immunoconvergent binding motif.  140:16615-16624. 2018
  • Enhancing protein stability with genetically encoded noncanonical amino acids.  140:15997-16000. 2018
  • Progress toward a semi-synthetic organism with an unrestricted expanded genetic alphabet.  140:16115-16123. 2018
  • Catalytic regio- and enantioselective haloazidation of allylic alcohols.  140:15646-15650. 2018
  • Synergistic bimetallic Ni/Ag and Ni/Cu catalysis for regioselective γ,δ-diarylation of alkenyl ketimines: addressing β-H elimination by in situ generation of cationic Ni(II) catalysts.  140:15586-15590. 2018
  • Design of a DNA-programmed plasminogen activator.  140:15516-15524. 2018
  • Diprovocims: A new and exceptionally potent class of toll-like receptor agonists.  140:14440-14454. 2018
  • Dynamic and responsive DNA-like polymers.  140:13594-13598. 2018
  • Cytochrome P450-catalyzed hydroxylation initiating ether formation in platensimycin biosynthesis.  140:12349-12353. 2018
  • Mixed explicit-implicit solvation approach for modeling of alkane complexation in water-soluble self-assembled capsules.  140:12527-12537. 2018
  • Synthesis and mechanochemical activation of ladderene-norbornene block copolymers.  140:12388-12391. 2018
  • Mechanistic interrogation of Co/Ni-dual catalyzed hydroarylation.  140:12056-12068. 2018
  • Secondary photocrosslinking of click hydrogels to probe myoblast mechanotransduction in three dimensions.  140:11585-11588. 2018
  • Bacterial genome containing chimeric DNA-RNA sequences.  140:11464-11473. 2018
  • Copper-catalyzed electrochemical C-H amination of arenes with secondary amines.  140:11487-11494. 2018
  • Iron-nickel dual-catalysis: a new engine for olefin functionalization and the formation of quaternary centers.  140:11317-11324. 2018
  • Rhodium-catalyzed B-H bond insertion reactions of unstabilized diazo compounds generated in situ from tosylhydrazones.  140:10663-10668. 2018
  • C-H functionalization of amines via alkene-derived nucleophiles through cooperative action of chiral and achiral lewis acid catalysts: applications in enantioselective synthesis.  140:10593-10601. 2018
  • Enantioselective synthesis of oseltamivir phosphate (Tamiflu) via the iron-catalyzed stereoselective olefin diazidation.  140:10619-10626. 2018
  • Ligand-enabled β-C(sp3)-H olefination of free carboxylic acids.  140:10363-10367. 2018
  • Ni-catalyzed regioselective alkylarylation of vinylarenes via C(sp3)–C(sp3)/C(sp3)–C(sp2) bond formation and mechanistic studies.  140:9801-9805. 2018
  • Total Synthesis of Septedine and 7-Deoxyseptedine.  140:9025-9029. 2018
  • Total synthesis of aplysiasecosterol A.  140:9211-9218. 2018
  • Direct access to versatile electrophiles via catalytic oxidative cyanation of alkenes.  140:8069-8073. 2018
  • Extrinsic tryptophans as NMR probes of allosteric coupling in membrane proteins: application to the A2A adenosine receptor.  140:8228-8235. 2018
  • Ni-catalyzed regioselective β,δ-diarylation of unactivated olefins in ketimines via ligand-enabled contraction of transient nickellacycles: rapid access to remotely diarylated ketones.  140:7782-7786. 2018
  • Divergent synthesis of pyrone diterpenes via radical cross coupling.  140:7462-7465. 2018
  • Modulation of fluorescent protein chromophores to detect protein aggregation with turn-on fluorescence.  140:7381-7384. 2018
  • Osmolytes and protein-protein interactions.  140:7441-7444. 2018
  • Small molecule targeted recruitment of a nuclease to RNA.  140:6741-6744. 2018
  • Pd(II)-catalyzed enantioselective C(sp(3))-H arylation of free carboxylic acids.  140:6545-6549. 2018
  • C(alkenyl)-H activation via six-membered palladacycles: catalytic 1,3-diene synthesis.  140:5805-5813. 2018
  • Enantioselective γ-C(sp3)-H activation of alkyl amines via Pd(II)/Pd(0) catalysis.  140:5322-5325. 2018
  • An oxetane-based polyketide surrogate To probe substrate binding in a polyketide synthase.  140:4961-4964. 2018
  • Copper-catalyzed vinylogous aerobic oxidation of unsaturated compounds with air.  140:5300-5310. 2018
  • Unprecedented role of hybrid N-glycans as ligands for HIV-1 broadly neutralizing antibodies.  140:5202-5210. 2018
  • Natural product total synthesis: as exciting as ever and here to stay.  140:4751-4755. 2018
  • Nickel-catalyzed dearomative trans-1,2-carboamination.  140:4503-4507. 2018
  • Total synthesis of hybridaphniphylline B.  140:4227-4231. 2018
  • Functional replacement of histidine in proteins to generate noncanonical amino acid dependent organisms.  140:3829-3832. 2018
  • Analyte-driven disassembly and turn-on fluorescent sensing in competitive biological media.  140:3500-3504. 2018
  • Ligand-enabled γ-C(sp3)-H activation of ketones.  140:3564-3568. 2018
  • Mechanistic investigation and multiplexing of liposome-assisted metabolic glycan labeling.  140:3592-3602. 2018
  • Catalytic carbo- and aminoboration of alkenyl carbonyl compounds via five- and six-membered palladacycles.  140:3223-3227. 2018
  • Catalytically active single-chain polymeric nanoparticles: exploring their functions in complex biological media.  140:3423-3433. 2018
  • Enantioselective synthesis of pyrroloindolines via noncovalent stabilization of indole radical cations and applications to the synthesis of alkaloid natural products.  140:3394-3402. 2018
  • SuFEx click chemistry enabled late-stage drug functionalization.  140:2919-2925. 2018
  • Scalable access to arylomycins via C-H functionalization logic.  140:2072-2075. 2018
  • Total synthesis of (-)-xylogranatopyridine B via a palladium-catalyzed oxidative stannylation of enones.  140:2062-2066. 2018
  • Controlled formation and binding selectivity of discrete oligo(methyl methacrylate) stereocomplexes.  140:1945-1951. 2018
  • Promysalin elicits species-selective inhibition of pseudomonas aeruginosa by targeting succinate dehydrogenase.  140:1774-1782. 2018
  • A tool for the import of natural and unnatural nucleoside triphosphates into bacteria.  140:1447-1454. 2018
  • Macrocyclization of interferon-poly(α-amino acid) conjugates significantly improves the tumor retention, penetration, and antitumor efficacy.  140:1170-1178. 2018
  • Total synthesis of the caged indole alkaloid arboridinine enabled by aza-Prins and metal-mediated cyclizations.  140:919-925. 2018
  • Mechanism of the Ullmann biaryl ether synthesis catalyzed by complexes of anionic ligands: Evidence for the reaction of iodoarenes with ligated anionic Cu-I intermediates.  140:793-806. 2018
  • Reprograming the replisome of a semisynthetic organism for the expansion of the genetic alphabet.  140:758-765. 2018
  • Slow dynamics of tryptophan-water networks in proteins.  140:675-682. 2018
  • "Inverse drug discovery" strategy to identify proteins that are targeted by latent electrophiles as exemplified by aryl fluorosulfates.  140:200-210. 2018
  • Remote C-H hydroxylation by an α-ketoglutarate-dependent dioxygenase enables efficient chemoenzymatic synthesis of manzacidin C and proline analogs.  140:1165-1169. 2018
  • Dynamic ligand exchange as a mechanistic probe in Pd-catalyzed enantioselective C-H functionalization reactions using monoprotected amino acid ligands.  139:18500-18503. 2017
  • Engineering bifunctional antibodies with constant region fusion architectures.  139:18607-18615. 2017
  • Total syntheses of scaparvins B, C, and D enabled by a Key C-H functionalization.  139:18428-18431. 2017
  • Palladium-catalyzed dearomative syn-1,4-carboamination.  139:17787-17790. 2017
  • Total syntheses of (-)-majucin and (-)-jiadifenoxolane A, complex majucin-type illicium sesquiterpenes.  139:17783-17786. 2017
  • Investigation of trimethyllysine binding by the HP1 chromodomain via unnatural amino acid mutagenesis.  139:17253-17256. 2017
  • Versatile alkylation of (hetero)aryl iodides with ketones via β-C(sp3)-H activation.  139:16080-16083. 2017
  • Synthesis of (+)-pancratistatins via catalytic desymmetrization of benzene.  139:15656-15659. 2017
  • Synthesis of Z- or E-trisubstituted allylic alcohols and ethers by kinetically controlled cross-metathesis with a Ru catechothiolate complex.  139:15640-15643. 2017
  • Tridentate directing groups stabilize 6-membered palladacycles in catalytic alkene hydrofunctionalization.  139:15576-15579. 2017
  • Mechanistic insight into the photocontrolled cationic polymerization of vinyl ethers.  139:15530-15538. 2017
  • Quantum chemical modeling of cycloaddition reaction in a self-assembled capsule.  139:15494-15503. 2017
  • Total synthesis of longeracinphyllin A.  139:14893-14896. 2017
  • Enantiospecific solvolytic functionalization of bromochlorides.  139:13562-13569. 2017
  • Modular, scalable synthesis of group A streptogramin antibiotics.  139:13304-13307. 2017
  • Residues comprising the enhanced aromatic sequon influence protein N-glycosylation efficiency.  139:12947-12955. 2017
  • CD22 ligands on a natural N-glycan scaffold efficiently deliver toxins to B-lymphoma cells.  139:12450-12458. 2017
  • Cu(II)-catalyzed ortho-selective aminomethylation of phenols.  139:12390-12393. 2017
  • Cyanine conformational restraint in the far-red range.  139:12406-12409. 2017
  • Genetically encoded fluorescent probe for detecting sirtuins in living cells.  139:12350-12353. 2017
  • Highly versatile β-C(sp3)-H iodination of ketones using a practical auxiliary.  139:12394-12397. 2017
  • Recombinant macrocyclic lanthipeptides incorporating non-canonical amino acids.  139:11646-11649. 2017
  • Chemically controlled epigenome editing through an inducible dCas9 system.  139:11337-11340. 2017
  • In vivo structure-activity relationships and optimization of an unnatural base pair for replication in a semi-synthetic organism.  139:11427-11433. 2017
  • Catalytic intermolecular carboamination of unactivated alkenes via directed aminopalladation.  139:11261-11270. 2017
  • Defining the structural basis for allosteric product release from E. coli dihydrofolate reductase using NMR relaxation dispersion.  139:11233-11240. 2017
  • Isomer-specific hydrogen bonding as a design principle for bidirectionally quantitative and redshifted hemithioindigo photoswitches.  139:10956-10959. 2017
  • Experimental and computational development of a conformationally flexible template for the meta-C-H functionalization of benzoic acids.  139:10702-10714. 2017
  • Ni-catalyzed regioselective 1,2-dicarbofunctionalization of olefins by intercepting Heck intermediates as imine-stabilized transient metallacycles.  139:10653-10656. 2017
  • Nickel-catalyzed β,γ-dicarbofunctionalization of alkenyl carbonyl compounds via conjunctive cross-coupling.  139:10657-10660. 2017
  • Photocontrolled interconversion of cationic and radical polymerizations.  139:10665-10668. 2017
  • Polymerase chain transcription: exponential synthesis of RNA and modified RNA.  139:9949-9954. 2017
  • Small molecule recognition triggers secondary and tertiary interactions in DNA folding and hammerhead ribozyme catalysis.  139:9815-9818. 2017
  • Synthesis of (-)-11-O-debenzoyltashironin: neurotrophic sesquiterpenes cause hyperexcitation.  139:9637-9644. 2017
  • A role for Pd(IV) in catalytic enantioselective C-H functionalization with monoprotected amino acid ligands under mild conditions.  139:9238-9245. 2017
  • Programmable assembly of peptide amphiphile via noncovalent-to-covalent bond conversion.  139:8995-9000. 2017
  • Water dynamics from the surface to the interior of a supramolecular nanostructure.  139:8915-8921. 2017
  • Development of a clinically viable heroin vaccine.  139:8601-8611. 2017
  • The origins of dramatic differences in five-membered vs six-membered chelation of Pd(II) on efficiency of C(sp3)-H bond activation.  139:8514-8521. 2017
  • Co-assembly of peptide amphiphiles and lipids into supramolecular nanostructures driven by anion-π interactions.  139:7823-7830. 2017
  • Covalent capture of aligned self-assembling nanofibers.  139:8044-8050. 2017
  • Heterogeneous-backbone foldamer mimics of zinc finger tertiary structure.  139:7931-7938. 2017
  • Scalable, electrochemical oxidation of unactivated C-H bonds.  139:7448-7451. 2017
  • Metal ions effectively ablate the action of Botulinum neurotoxin A.  139:7264-7272. 2017
  • Design of benzoxathiazin-3-one 1,1-dioxides as a new class of irreversible serine hydrolase inhibitors: Discovery of a uniquely selective PNPLA4 inhibitor.  139:7052-7061. 2017
  • Enantioselective chemical syntheses of the furanosteroids (-)-viridin and (-)-viridiol.  139:6819-6822. 2017
  • Potassium tert-butoxide-catalyzed dehydrogenative C-H silylation of heteroaromatics: A combined experimental and computational mechanistic study.  139:6867-6879. 2017
  • Isolable and readily handled halophosphonium pre-reagents for hydro- and deuteriohalogenation.  139:6329-6337. 2017
  • Crystal-phase transitions and photocatalysis in supramolecular scaffolds.  139:6120-6127. 2017
  • Copper-catalyzed dicarbofunctionalization of unactivated olefins by tandem cyclization/cross-coupling.  139:5700-5703. 2017
  • Generation of an orthogonal protein-protein interface with a noncanonical amino acid.  139:5728-5731. 2017
  • Ligand-enabled Pd(II)-catalyzed bromination and iodination of C(sp3)-H bonds.  139:5724-5727. 2017
  • Stolonidiol: Synthesis, target identification, and mechanism for choline acetyltransferase activation.  139:5865-5869. 2017
  • Diverse redoxome reactivity profiles of carbon nucleophiles.  139:5588-5595. 2017
  • Total synthesis and stereochemical assignment of delavatine A: Rh-catalyzed asymmetric hydrogenation of indene-type tetrasubstituted olefins and kinetic resolution through Pd catalyzed triflamide-directed C-H olefination.  139:5558-5567. 2017
  • Enantiospecific total synthesis of the highly strained (-)-presilphiperfolan-8-ol via a Pd-catalyzed tandem cyclization.  139:5007-5010. 2017
  • Palladium(II)-catalyzed directed anti-hydrochlorination of unactivated alkynes with HCl.  139:5183-5193. 2017
  • Peptide macrocyclization inspired by non-ribosomal imine natural products.  139:5233-5241. 2017
  • Regulating miRNA-21 biogenesis by bifunctional small molecules.  139:4987-4990. 2017
  • Stereochemistry of endogenous palmitic acid ester of 9-hydroxystearic acid and relevance of absolute configuration to regulation.  139:4943-4947. 2017
  • Catalytic B-H bond insertion reactions using alkynes as carbene precursors.  139:3784-3789. 2017
  • Stereocontrolled synthesis of kalihinol C.  139:3647-3650. 2017
  • Efficient liver targeting by polyvalent display of a compact ligand for the asialoglycoprotein receptor.  139:3528-3536. 2017
  • Pd(II)-catalyzed enantioselective C(sp(3))-H borylation.  139:3344-3347. 2017
  • Small molecule inhibition of microRNA-210 reprograms an oncogenic hypoxic circuit.  139:3446-3455. 2017
  • Glutamine amide flip elicits long distance allosteric responses in the LOV protein vivid.  139:2972-2980. 2017
  • Palladium-catalyzed C(sp(3))-H oxygenation via electrochemical oxidation.  139:3293-3298. 2017
  • Selection of 2'-fluoro-modified aptamers with optimized properties.  139:2892-2895. 2017
  • Strain-release heteroatom functionalization: Development, scope, and stereospecificity.  139:3209-3226. 2017
  • Supramolecular "Trojan Horse" for nuclear delivery of dual anticancer drugs.  139:2876-2879. 2017
  • Structure-activity relationship and molecular mechanics reveal the importance of ring entropy in the biosynthesis and activity of a natural product.  139:2541-2544. 2017
  • Chemical stabilization of unnatural nucleotide triphosphates for the in vivo expansion of the genetic alphabet.  139:2464-2467. 2017
  • Fe-catalyzed C-C bond construction from olefins via radicals.  139:2484-2503. 2017
  • Rh(III)-catalyzed meta-C-H olefination directed by a nitrile template.  139:2200-2203. 2017
  • Supramolecular metal-coordination polymers, nets, and frameworks from synthetic coiled-coil peptides.  139:2212-2215. 2017
  • Total synthesis of (±)-berkeleyone A.  139:1790-1793. 2017
  • Antimicrobials inspired by nonribosomal peptide synthetase gene clusters.  139:1404-1407. 2017
  • Critical analysis of rate constants and turnover frequency in nucleic acid-templated reactions: reaching terminal velocity.  139:1444-1447. 2017
  • Fluorescence turn-on sensing of DNA duplex formation by a tricyclic cytidine analogue.  139:1372-1375. 2017
  • Assembly of the limonoid architecture by a divergent approach: total synthesis of (±)-andirolide N via (±)-8α-hydroxycarapin.  139:631-634. 2017
  • Covalent modulators of the vacuolar ATPase.  139:639-642. 2017
  • Diverse ortho-C(sp(2))-H functionalization of benzaldehydes using transient directing groups.  139:888-896. 2017
  • Concurrent modulation of quantum dot photoluminescence using a combination of charge transfer and Forster resonance energy transfer: competitive quenching and multiplexed biosensing modality.  139:363-372. 2017
  • Frustrated Lewis acid/Brønsted base catalysts for direct enantioselective α-amination of carbonyl compounds.  139:95-98. 2017
  • Ligand-enabled meta-selective C-H arylation of nosyl-protected phenethylamines, benzylamines, and 2-aryl anilines.  139:417-425. 2017
  • Strained cyclic disulfides enable cellular uptake by reacting with the transferrin receptor.  139:231-238. 2017
  • Biosynthetic origin of the ether ring in platensimycin.  138:16711-16721. 2016
  • Oxidative entry into the illicium sesquiterpenes: enantiospecific synthesis of (+)-pseudoanisatin.  138:16616-16619. 2016
  • Cucurbit 7 uril-tetramethylrhodamine conjugate for direct sensing and cellular imaging.  138:16549-16552. 2016
  • Chemical synthesis and self-assembly of a ladderane phospholipid.  138:15845-15848. 2016
  • Metabolically labile fumarate esters impart kinetic selectivity to irreversible inhibitors.  138:15841-15844. 2016
  • Cationic polymerization of vinyl ethers controlled by visible light.  138:15535-15538. 2016
  • Total syntheses of aflavazole and 14-hydroxyaflavinine.  138:15555-15558. 2016
  • β,γ-vicinal dicarbofunctionalization of alkenyl carbonyl compounds via directed nucleopalladation.  138:15122-15125. 2016
  • Annulative methods enable a total synthesis of the complex meroterpene berkeleyone A.  138:14868-14871. 2016
  • Ligand promoted meta-C-H chlorination of anilines and phenols.  138:14876-14879. 2016
  • Catalytic, regioselective hydrocarbofunctionalization of unactivated alkenes with diverse C-H nucleophiles.  138:14705-14712. 2016
  • Pd-catalyzed γ-C(sp(3))-H arylation of free amines using a transient directing group.  138:14554-14557. 2016
  • 11-step total synthesis of araiosamines.  138:14234-14237. 2016
  • Replacement of 2 '-deoxycytidine by 2 '-deoxycytidine analogues in the E. coli genome.  138:14230-14233. 2016
  • Ligand-promoted meta-C-H amination and alkynylation.  138:14092-14099. 2016
  • Z-Selective cross-metathesis and homodimerization of 3E-1,3-dienes: reaction optimization, computational analysis, and synthetic applications.  138:14039-14046. 2016
  • Chemical proteomic profiling of human methyltransferases.  138:13335-13343. 2016
  • Hydrogen-bonded homoleptic fluoride-diarylurea complexes: structure, reactivity, and coordinating power.  138:13314-13325. 2016
  • Analysis of Loops that Mediate Protein-Protein Interactions and Translation into Submicromolar Inhibitors.  138:12876-12884. 2016
  • Branch-selective hydroarylation: iodoarene-olefin cross-coupling.  138:12779-12782. 2016
  • Evolutionary gain of alanine mischarging to noncognate tRNAs with a G4:U69 base pair.  138:12948-12955. 2016
  • Palladium(II)-catalyzed regioselective syn-hydroarylation of disubstituted alkynes using a removable directing group.  138:13076-13081. 2016
  • Radicals: reactive intermediates with translational potential.  138:12692-12714. 2016
  • Catalysis of heterocyclic azadiene cycloaddition reactions by solvent hydrogen bonding: concise total synthesis of methoxatin.  138:12408-12413. 2016
  • Discovery of enzymatic targets of transcriptional activators via in vivo covalent chemical capture.  138:12629-12635. 2016
  • Identification of mechanism-based inactivation in P450-catalyzed cyclopropanation facilitates engineering of improved enzymes.  138:12527-12533. 2016
  • Extended-charge-transfer excitons in crystalline supramolecular photocatalytic scaffolds.  138:11762-11774. 2016
  • Activation of cell-penetrating peptides with Ionpair-π interactions and fluorophiles.  138:11264-11271. 2016
  • Iron(II)-catalyzed intermolecular aminofluorination of unfunctionalized olefins using fluoride ion.  138:11360-11367. 2016
  • Redox-active esters in Fe-catalyzed C-C coupling.  138:11132-11135. 2016
  • Macrocyclization of folded diamines in cavitands.  138:10846-10848. 2016
  • Structure of the ent-copalyl diphosphate synthase PtmT2 from streptomyces platensis CB00739, a bacterial type II diterpene synthase.  138:10905-10915. 2016
  • Finding our way in the dark proteome.  138:9730-9742. 2016
  • 11-step total synthesis of (-)-maoecrystal V.  138:9425-9428. 2016
  • HtrA1 proteolysis of ApoE in vitro is allele selective.  138:9473-9478. 2016
  • Ligand-promoted meta-C-H arylation of anilines, phenols, and heterocycles.  138:9269-9276. 2016
  • Structural analysis of human Argonaute-2 bound to a modified siRNA guide.  138:8694-8697. 2016
  • Structure-guided control of siRNA off-target effects.  138:8667-8669. 2016
  • Synthesis of a potent vinblastine: rationally designed added benign complexity.  138:8376-8379. 2016
  • Streamlined total synthesis of uncialamycin and its application to the synthesis of designed analogues for biological investigations.  138:8235-8246. 2016
  • 11-step total synthesis of pallambins C and D.  138:7536-7539. 2016
  • Cavitands as chaperones for monofunctional and ring-forming reactions in water.  138:7512-7515. 2016
  • Kinetic resolution of benzylamines via palladium(II)-catalyzed C-H cross-coupling.  138:7796-7800. 2016
  • The dependence of carbohydrate-aromatic interaction strengths on the structure of the carbohydrate.  138:7636-7648. 2016
  • Arylfluorosulfates inactivate intracellular lipid binding protein(s) through chemoselective SuFEx reaction with a binding site Tyr residue.  138:7353-7364. 2016
  • Replacement of Thymidine by a Modified Base in the Escherichia coli Genome.  138:7272-7275. 2016
  • Synthesis of (+)-7,20-diisocyanoadociane and liver -stage antiplasmodial activity of the isocyanoterpene class.  138:7268-7271. 2016
  • In situ catalyst modification in atom transfer radical reactions with ruthenium benzylidene complexes.  138:7171-7177. 2016
  • Methionine ligand interaction in a blue copper protein characterized by site-selective infrared spectroscopy.  138:7187-7193. 2016
  • Synthesis and biological investigation of Δ12-prostaglandin J3 (Δ12-PGJ3) analogues and related compounds.  138:6550-6560. 2016
  • A versatile and scalable strategy to discrete oligomers.  138:6306-6310. 2016
  • Chemical tools to monitor and manipulate adaptive immune responses.  138:6076-6094. 2016
  • Directed, regiocontrolled hydroamination of unactivated alkenes via protodepalladation.  138:5805-5808. 2016
  • Diverted total synthesis of promysalin analogs demonstrates that an iron-binding motif is responsible for its narrow-spectrum antibacterial activity.  138:5833-5836. 2016
  • Cellular protection of SNAP-25 against botulinum neurotoxin/A: inhibition of thioredoxin reductase through a suicide substrate mechanism.  138:5568-5575. 2016
  • A carbohydrate-derived splice modulator.  138:5063-5068. 2016
  • Catalytic enantioselective dihalogenation and the selective synthesis of (-)-deschloromytilipin A and (-)-danicalipin A.  138:5150-5158. 2016
  • Ph(i-PrO)SiH2: An exceptional reductant for metal-catalyzed hydrogen atom transfers.  138:4962-4971. 2016
  • Single hydrogen bond donation from flavin N-5 to proximal asparagine ensures FAD reduction in DNA photolyase.  138:4368-4376. 2016
  • Asymmetric total syntheses of aspidodasycarpine, lonicerine, and the proposed structure of lanciferine.  138:3982-3985. 2016
  • Trapping of the enoyl-acyl carrier protein reductase-acyl carrier protein interaction.  138:3962-3965. 2016
  • Capturing unknown substrates via in situ formation of tightly bound bisubstrate adducts: S-adenosyl-vinthionine as a functional probe for AdoMet-dependent methyltransferases.  138:2877-2880. 2016
  • Pd-catalyzed α-selective C-H functionalization of olefins: en route to 4-Imino-β-lactams.  138:2146-2149. 2016
  • Practical Ni-catalyzed aryl-alkyl cross-coupling of secondary redox-active esters.  138:2174-2177. 2016
  • Ligand-enabled γ-C(sp(3))-H olefination of amines: en route to pyrrolidines.  138:2055-2059. 2016
  • Steric and dynamic parameters influencing in situ cycloadditions to form triazole inhibitors with crystalline acetylcholinesterase.  138:1611-1621. 2016
  • Amide α,β-dehydrogenation using allyl-palladium catalysis and a hindered monodentate anilide.  138:1166-1169. 2016
  • Discovery of pyrophosphate diesters as tunable, soluble, and bioorthogonal linkers for site-specific antibody-drug conjugates.  138:1430-1445. 2016
  • Resolution of site-specific conformational heterogeneity in proline-rich molecular recognition by Src homology 3 domains.  138:1130-1133. 2016
  • Tilted magnetic levitation enables measurement of the complete range of densities of materials with low magnetic permeability.  138:1252-1257. 2016
  • Site-selective aliphatic C-H chlorination using N-chloroamides enables a synthesis of chlorolissoclimide.  138:696-702. 2016
  • Silent encoding of chemical post-translational modifications in phage-displayed libraries.  138:32-35. 2016
  • An evolved orthogonal enzyme/cofactor pair.  138:12451-12458. 2016
  • Controlling the architecture, coordination, and reactivity of nanoparticle coating utilizing an amino acid central scaffold.  137:16084-16097. 2015
  • Specific inhibition of microRNA processing using L-RNA aptamers.  137:16032-16037. 2015
  • Supramolecular packing controls H-2 photocatalysis in chromophore amphiphile hydrogels.  137:15241-15246. 2015
  • A deep cavitand templates lactam formation in water.  137:14582-14585. 2015
  • Iridium-catalyzed enantioselective allylic substitution of enol silanes from vinylogous esters and amides.  137:13972-13979. 2015
  • Scalable C-H oxidation with copper: synthesis of polyoxypregnanes.  137:13776-13779. 2015
  • Total synthesis of Epoxyeujindole A.  137:13764-13767. 2015
  • A fluorinated ligand enables room-temperature and regioselective Pd-catalyzed fluorination of aryl triflates and bromides.  137:13433-13438. 2015
  • Mono-oxidation of bidentate bis-phosphines in catalyst activation: kinetic and mechanistic studies of a Pd/xantphos-catalyzed C-H functionalization.  137:13272-13281. 2015
  • Highly selective synthesis of halomon, plocamenone, and isoplocamenone.  137:12784-12787. 2015
  • Modular synthetic platform for the construction of functional single-chain polymeric nanoparticles: from aqueous catalysis to photosensitization.  137:13096-13105. 2015
  • α-Arylation of saturated azacycles and N-methylamines via palladium(II)-catalyzed C(sp(3))-H coupling.  137:11876-11879. 2015
  • Ligand-enabled meta-C-H alkylation and arylation using a modified norbornene.  137:11574-11577. 2015
  • Structure and substrate sequestration in the pyoluteorin type II peptidyl carrier protein PltL.  137:11546-11549. 2015
  • Fluorescence turn-on folding sensor to monitor proteome stress in live cells.  137:11303-11311. 2015
  • Systematic evaluation of bioorthogonal reactions in live cells with clickable Halo Tag ligands: implications for intracellular imaging.  137:11461-11475. 2015
  • Kinetic profiling of catalytic organic reactions as a mechanistic tool.  137:10852-10866. 2015
  • Practical Pd(II)-catalyzed C-H alkylation with epoxides: one-step syntheses of 3,4-dihydroisocoumarins.  137:10950-10953. 2015
  • Total synthesis of hyperforin.  137:10516-10519. 2015
  • Total synthesis of verruculogen and fumitremorgin a enabled by ligand-controlled C-H borylation.  137:10160-10163. 2015
  • Monoselective o-C-H functionalizations of mandelic acid and α-phenylglycine.  137:9877-9884. 2015
  • Cofactor-mediated conformational dynamics promote product release from Escherichia coli dihydrofolate reductase via an allosteric pathway.  137:9459-9468. 2015
  • Mechanistic details of Pd(II)-catalyzed C-H iodination with molecular I-2: oxidative addition vs electrophilic cleavage.  137:9022-9031. 2015
  • Synthetic polymer hybridization with DNA and RNA directs nanoparticle loading, silencing delivery, and aptamer function.  137:8920-8923. 2015
  • Highly selective, reversible inhibitor identified by comparative chemoproteomics modulates diacylglycerol lipase activity in neurons.  137:8851-8857. 2015
  • A general approach to sequence-controlled polymers using macrocyclic ring opening metathesis polymerization.  137:8038-8041. 2015
  • Biochemical establishment and characterization of EncM's Flavin-N5-oxide cofactor.  137:8078-8085. 2015
  • Hydromethylation of unactivated olefins.  137:8046-8049. 2015
  • A fluorogenic aryl fluorosulfate for intraorganellar transthyretin imaging in living cells and in Caenorhabditis elegans.  137:7404-7414. 2015
  • A synthesis of alsmaphorazine B demonstrates the chemical feasibility of a new biogenetic hypothesis.  137:7306-7309. 2015
  • Total synthesis and biological investigation of (-)-promysalin.  137:7314-7317. 2015
  • CalFluors: A universal motif for fluorogenic azide probes across the visible spectrum.  137:7145-7151. 2015
  • Chemical protein synthesis using a second-generation N-acylurea linker for the preparation of peptide-thioester precursors.  137:7197-7209. 2015
  • Ligand-enabled stereoselective β-C(sp(3))-H fluorination: Synthesis of unnatural enantiopure anti-β-fluoro-α-amino acids.  137:7067-7070. 2015
  • Computational and experimental investigations of the formal dyotropic rearrangements of Himbert arene/allene cycloadducts.  137:6956-6964. 2015
  • A reversible and highly selective inhibitor of the proteasomal ubiquitin receptor rpn13 is toxic to multiple myeloma cells.  137:6312-6319. 2015
  • Palladium-catalyzed α,β-dehydrogenation of esters and nitriles.  137:5875-5878. 2015
  • γ,δ,ε-C(sp(3))-H functionalization through directed radical H-abstraction.  137:5871-5874. 2015
  • Origins of initiation rate differences in ruthenium olefin metathesis catalysts containing chelating benzylidenes.  137:5782-5792. 2015
  • An anti-B cell maturation antigen bispecific antibody for multiple myeloma.  137:5288-5291. 2015
  • Genetically encoded fragment-based discovery of glycopeptide ligands for carbohydrate-binding proteins.  137:5248-5251. 2015
  • Inhibition of non-ATG translational events in cells via covalent small molecules targeting RNA.  137:5336-5345. 2015
  • Photoligation of an amphiphilic polymer with mixed coordination provides compact and reactive quantum dots.  137:5438-5451. 2015
  • Structural elucidation and synthesis of eudistidine A: an unusual polycyclic marine alkaloid that blocks interaction of the protein binding domains of p300 and HIF-1α.  137:5569-5575. 2015
  • Modular degradable hydrogels based on thiol-reactive oxanorbornadiene linkers.  137:4984-4987. 2015
  • Synthesis and potent antimalarial activity of kalihinol B.  137:4912-4915. 2015
  • Drug-triggered and cross-linked self-assembling nanofibrous hydrogels.  137:4823-4830. 2015
  • Ligand-enabled cross-coupling of C(sp(3))-H bonds with arylsilanes.  137:4618-4621. 2015
  • Synthesis and biological evaluation of dimeric furanoid macroheterocycles: discovery of new anticancer agents.  137:4766-4770. 2015
  • Pd(II)-catalyzed C-H functionalizations directed by distal weakly coordinating functional groups.  137:4391-4397. 2015
  • Rational design of antibody protease inhibitors.  137:4042-4045. 2015
  • Catalytic chemo-, regio-, and enantioselective bromochlorination of allylic alcohols.  137:3795-3798. 2015
  • Peptide ligation and RNA cleavage via an abiotic template interface..  137:3751-3754. 2015
  • Sequence-specific, nanomolar peptide binding via cucurbit[8]uril-induced folding and inclusion of neighboring side chains.  137:3663-3669. 2015
  • Total syntheses and initial evaluation of [?[C(-S)NH]Tpg(4)]vancomycin, [?[C(-NH)NH]Tpg(4)]vancomycin, [?[CH2NH]Tpg(4)]vancomycin, and their (4-Chlorobiphenyl)methyl derivatives: synergistic binding pocket and peripheral modifications for the glycopeptide antibiotics.  137:3693-3704. 2015
  • Ligand-enabled β-C-H arylation of α-amino acids using a simple and practical auxiliary.  137:3338-3351. 2015
  • Rational ligand design for the arylation of hindered primary amines guided by reaction progress kinetic analysis.  137:3085-3092. 2015
  • Redirection of genetically engineered CAR-T cells using bifunctional small molecules.  137:2832-2835. 2015
  • UV and sunlight driven photoligation of quantum dots: understanding the photochemical transformation of the ligands.  137:2704-2714. 2015
  • Mechanistic rationalization of unusual sigmoidal kinetic profiles in the Machetti-De Sarlo cycloaddition reaction.  137:2386-2391. 2015
  • Cooperative loading and release behavior of a metal-organic receptor.  137:1770-1773. 2015
  • Palladium(II)-catalyzed highly enantioselective C-H arylation of cyclopropylmethylamines.  137:2042-2046. 2015
  • Parahydrogen-induced polarization by pairwise replacement catalysis on Pt and Ir nanoparticles.  137:1938-1946. 2015
  • Development of a concise synthesis of ouabagenin and hydroxylated corticosteroid analogues.  137:1330-1340. 2015
  • Epoxide hydrolase-lasalocid a structure provides mechanistic insight into polyether natural product biosynthesis.  137:86-89. 2015
  • A new strategy for smoking cessation: characterization of a bacterial enzyme for the degradation of nicotine.  137:10136-10139. 2015
  • An immunosuppressive antibody-drug conjugate.  137:3229-3232. 2015
  • Data-driven synthesis of proteolysis-resistant peptide hormones.  136:17710-17713. 2014
  • Rectification in tunneling junctions: 2,2'-bipyridyl-terminated n-alkanethiolates.  136:17155-17162. 2014
  • Criteria for selecting PEGylation sites on proteins for higher thermodynamic and proteolytic stability.  136:17547-17560. 2014
  • Tapping a bacterial enzymatic pathway for the preparation and manipulation of synthetic nanomaterials.  136:17378-17381. 2014
  • Modeling linear and cyclic PKS intermediates through atom replacement.  136:16792-16799. 2014
  • Simple, chemoselective, catalytic olefin isomerization.  136:16788-16791. 2014
  • Total synthesis of rubriflordilactone A.  136:16477-16480. 2014
  • Synthesis and biological evaluation of QRSTUVWXYZA' domains of maitotoxin.  136:16444-16451. 2014
  • Diastereo- and enantioselective iridium-catalyzed allylation of cyclic ketone enolates: synergetic effect of ligands and barium enolates.  136:15825-15828. 2014
  • Selective electrocatalytic oxidation of a re-methyl complex to methanol by a surface-bound Ru(II) polypyridyl catalyst.  136:15845-15848. 2014
  • Axinellamines as broad-spectrum antibacterial agents: scalable synthesis and biology.  136:15403-15413. 2014
  • Intramolecular [3 + 2] cyclocondensations of alkenes with indolidenes and indolidenium cations.  136:15138-15141. 2014
  • Long-range ordering of highly charged self-assembled nanofilaments.  136:14377-14380. 2014
  • Self-assembly of fiber-forming collagen mimetic peptides controlled by triple-helical nucleation.  136:14417-14424. 2014
  • A near-IR uncaging strategy based on cyanine photochemistry.  136:14153-14159. 2014
  • Evidence of an unusual N-H…N hydrogen bond in proteins.  136:13474-13477. 2014
  • Total synthesis of Psi C(=NH)NH Tpg(4) vancomycin and its ((4)-chlorobiphenyl)methyl derivative: impact of peripheral modifications on vancomycin analogues redesigned for dual D-Ala-D-Ala and D-Ala-D-Lac binding.  136:13522-13525. 2014
  • De novo-designed enzymes as small-molecule-regulated fluorescence imaging tags and fluorescent reporters.  136:13102-13105. 2014
  • Iron(II)-catalyzed intermolecular amino-oxygenation of olefins through the N-O bond cleavage of functionalized hydroxylamines.  136:13186-13189. 2014
  • Ligand-promoted alkylation of C(sp(3))-H and C(sp(2))-H bonds.  136:13194-13197. 2014
  • A potent α/β-peptide analogue of GLP-1 with prolonged action in vivo.  136:12848-12851. 2014
  • Asymmetric Mannich synthesis of α-amino esters by anion-binding catalysis.  136:12872-12875. 2014
  • Characterization of native protein complexes using ultraviolet photodissociation mass spectrometry.  136:12920-12928. 2014
  • A unified approach to ent-atisane diterpenes and related alkaloids: synthesis of (-)-methyl atisenoate, (-)-isoatisine, and the hetidine skeleton.  136:12592-12595. 2014
  • Total synthesis of viridicatumtoxin B and analogues thereof: strategy evolution, structural revision, and biological evaluation.  136:12137-12160. 2014
  • Cu(II)-mediated ortho C-H alkynylation of (hetero)arenes with terminal alkynes.  136:11590-11593. 2014
  • Tet-mediated formation of 5-hydroxymethylcytosine in RNA.  136:11582-11585. 2014
  • Glycocalyx remodeling with proteoglycan mimetics promotes neural specification in embryonic stem cells.  136:10565-10568. 2014
  • Mapping the protein interaction landscape for fully functionalized small-molecule probes in human cells.  136:10777-10782. 2014
  • Pd(II)-catalyzed meta-C-H olefination, arylation, and acetoxylation of indolines using a U-shaped template.  136:10807-10813. 2014
  • Rational design of CXCR4 specific antibodies with elongated CDRs.  136:10557-10560. 2014
  • A mechanistic change results in 100 times faster CH functionalization for ethane versus methane by a homogeneous Pt catalyst.  136:10085-10094. 2014
  • Concerted versus stepwise mechanism in thymidylate synthase.  136:9850-9853. 2014
  • A strategy for complex dimer formation when biomimicry fails: total synthesis of ten coccinellid alkaloids.  136:9743-9753. 2014
  • A genetically encoded aza-Michael acceptor for covalent cross-linking of protein-receptor complexes.  136:8411-8417. 2014
  • Rapid, hydrolytically stable modification of aldehyde-terminated proteins and phage libraries.  136:8149-8152. 2014
  • Selective monooxidation of light alkanes using chloride and iodate.  136:8393-8401. 2014
  • Synthesis of angularly substituted trans-fused hydroindanes by convergent coupling of acyclic precursors.  136:8209-8212. 2014
  • Total synthesis of taiwaniadducts B, C, and D.  136:8185-8188. 2014
  • Palladium(II)-catalyzed enantioselective C(sp(3))-H activation using a chiral hydroxamic acid ligand.  136:8138-8142. 2014
  • Rational design of a non-canonical "sticky-ended" collagen triple helix.  136:7535-7538. 2014
  • Bifacial peptide nucleic acid as an allosteric switch for aptamer and ribozyme function.  136:7265-7268. 2014
  • Palau'chlor: a practical and reactive chlorinating reagent.  136:6908-6911. 2014
  • Molecular rotors as conditionally fluorescent labels for rapid detection of biomolecular interactions.  136:6159-6162. 2014
  • Development of a concise synthesis of (+)-ingenol.  136:5799-5810. 2014
  • Spontaneous prebiotic formation of a beta-ribofuranoside that self-assembles with a complementary heterocycle.  136:5640-5646. 2014
  • Total synthesis of dixiamycin B by electrochemical oxidation.  136:5571-5574. 2014
  • A mild, ferrocene-catalyzed C-H imidation of (hetero)arenes.  136:5279-5282. 2014
  • Alkyl groups fold to fit within a water-soluble cavitand.  136:5264-5266. 2014
  • Four-step synthesis of the antimalarial cardamom peroxide via an oxygen stitching strategy.  136:5287-5290. 2014
  • Ligand-enabled gamma-C-H olefination and carbonylation: construction of beta-quaternary carbon centers.  136:5267-5270. 2014
  • C-H methylation of heteroarenes inspired by radical SAM methyl transferase.  136:4853-4856. 2014
  • Enhancing the specificity of recombinase-mediated genome engineering through dimer interface redesign.  136:5047-5056. 2014
  • Total synthesis of halichondrin A, the missing member in the halichondrin class of natural products.  136:5171-5176. 2014
  • Two-phase synthesis of (-)-taxuyunnanine D.  136:4909-4912. 2014
  • Monitoring native p38α:MK2/3 complexes via trans delivery of an ATP acyl phosphate probe.  136:4664-4669. 2014
  • Palladium-catalyzed intramolecular asymmetric C-H functionalization/cyclization reaction of metallocenes: an efficient approach toward the synthesis of planar chiral metallocene compounds.  136:4472-4475. 2014
  • Cu(II)-mediated C-H amidation and amination of arenes: exceptional compatibility with heterocycles.  136:3354-3357. 2014
  • Formal carbene insertion into C-C bond: Rh(I)-catalyzed reaction of benzocyclobutenols with diazoesters.  136:3013-3015. 2014
  • Iridium-catalyzed enantioselective allyl-alkene coupling.  136:3006-3009. 2014
  • Stereodivergent α-allylation of linear aldehydes with dual iridium and amine catalysis.  136:3020-3023. 2014
  • Total syntheses of (-)-kopsifoline D and (-)-deoxoapodine: divergent total synthesis via late-stage key strategic bond formation.  136:3312-3317. 2014
  • Multifunctional π-expanded macrocyclic oligothiophene 6-mers and related macrocyclic oligomers.  136:2389-2396. 2014
  • Remodeling natural products: chemistry and serine hydrolase activity of a rocaglate-derived beta-lactone.  136:2659-2664. 2014
  • Quantitative analysis of rRNA modifications using stable isotope labeling and mass spectrometry.  136:2058-2069. 2014
  • Total syntheses of (-)-pyrimidoblamic acid and P-3A.  136:2119-2125. 2014
  • A practical and catalytic reductive olefin coupling.  136:1304-1307. 2014
  • Epitope discovery for a synthetic polymer nanoparticle: a new strategy for developing a peptide tag.  136:1194-1197. 2014
  • Simple, chemoselective hydrogenation with thermodynamic stereocontrol.  136:1300-1303. 2014
  • Natural-like replication of an unnatural base pair for the expansion of the genetic alphabet and biotechnology applications.  136:826-829. 2014
  • Role of N-acyl amino acid ligands in Pd(II)-catalyzed remote C-H activation of tethered arenes.  136:894-897. 2014
  • Determinants of regioselective hydroxylation in the fungal polysaccharide monooxygenases.  136:562-565. 2014
  • Palladium-catalyzed meta-selective C-H bond activation with a nitrile-containing template: computational study on mechanism and origins of selectivity.  136:344-355. 2014
  • Stereoselective 1,3-insertions of rhodium(II) azavinyl carbenes.  136:195-202. 2014
  • Site-selective C(sp3)-H functionalization of di-, tri-, and tetrapeptides at the N-terminus.  136:16940-16946. 2014
  • The designability of protein switches by chemical rescue of structure: mechanisms of inactivation and reactivation.  135:18840-18849. 2013
  • Structural insights into DNA replication without hydrogen bonds.  135:18637-18643. 2013
  • Synthesis of biologically active N- and O-linked glycans with multisialylated poly-N-acetyllactosamine extensions using P. damsela α2-6 sialyltransferase.  135:18280-18283. 2013
  • Cross-coupling of remote meta-C-H bonds directed by a U-shaped template.  135:18056-18059. 2013
  • Hydrogen-bonded capsules in water.  135:18064-18066. 2013
  • Stilbene vinyl sulfonamides as fluorogenic sensors of and traceless covalent kinetic stabilizers of transthyretin that prevent amyloidogenesis.  135:17869-17880. 2013
  • Computation and experiment reveal that the ring-rearrangement metathesis of Himbert cycloadducts can be subject to kinetic or thermodynamic control.  135:17585-17594. 2013
  • Ligand-accelerated ortho-C-H alkylation of arylcarboxylic acids using alkyl boron reagents.  135:17508-17513. 2013
  • Chemoproteomic discovery of cysteine-containing human short open reading frames.  135:16750-16753. 2013
  • Residue-dependent adsorption of model oligopeptides on gold.  135:15040-15052. 2013
  • Using reduced catalysts for oxidation reactions: mechanistic studies of the "Periana-Catalytica" system for CH4 oxidation.  135:14644-14658. 2013
  • Understanding the reactivity of Pd(0)/PR3-catalyzed intermolecular C(sp(3))-H bond arylation.  135:14206-14214. 2013
  • Amplified halogen bonding in a small space.  135:13672-13675. 2013
  • Site-specific antibody-polymer conjugates for siRNA delivery.  135:13885-13891. 2013
  • Binding of a structured D-RNA molecule by an L-RNA aptamer.  135:13290-13293. 2013
  • Computational design of an unnatural amino acid dependent metalloprotein with atomic level accuracy.  135:13393-13399. 2013
  • Mimicry of high-density lipoprotein: functional peptide-lipid nanoparticles based on multivalent peptide constructs.  135:13414-13424. 2013
  • Palladium-catalyzed carbene migratory insertion using conjugated ene-yne-ketones as carbene precursors.  135:13502-13511. 2013
  • Production of tartrates by cyanide-mediated dimerization of glyoxylate: a potential abiotic pathway to the citric acid cycle.  135:13440-13445. 2013
  • Targeted disruption of transcriptional regulators in Chaetomium globosum activates biosynthetic pathways and reveals transcriptional regulator-like behavior of aureonitol.  135:13446-13455. 2013
  • Bioconjugation by native chemical tagging of C-H bonds.  135:12994-12997. 2013
  • Catalytic enantioselective dibromination of allylic alcohols.  135:12960-12963. 2013
  • A genetically encoded fluorescent probe in mammalian cells.  135:12540-12543. 2013
  • Complete protein characterization using top-down mass spectrometry and ultraviolet photodissociation.  135:12646-12651. 2013
  • Protein-like tertiary folding behavior from heterogeneous backbones.  135:12528-12531. 2013
  • Selective detection and inhibition of active caspase-3 in cells with optimized peptides.  135:12869-12876. 2013
  • Cyclopentannulation of conjugated enones using a vinyldiazomethane-based reagent.  135:12188-12191. 2013
  • Radical-based regioselective C-H functionalization of electron-deficient heteroarenes: scope, tunability, and predictability.  135:12122-12134. 2013
  • Ultrafast structural dynamics inside planar phospholipid multibilayer model cell membranes measured with 2D IR spectroscopy.  135:11063-11074. 2013
  • Structural and thermodynamic basis of (+)-α-pinene binding to human cytochrome P450 2B6.  135:10433-10440. 2013
  • Development of a high-throughput screen and its use in the discovery of Streptococcus pneumoniae immunoglobulin A1 protease inhibitors.  135:10014-10017. 2013
  • Mutational analysis of 48G7 reveals that somatic hypermutation affects both antibody stability and binding affinity.  135:9980-9983. 2013
  • Engineering hydrophobic protein-carbohydrate interactions to fine-tune monoclonal antibodies.  135:9723-9732. 2013
  • Structural and energetic basis of carbohydrate-aromatic packing interactions in proteins.  135:9877-9884. 2013
  • Enantioselective synthesis of (Z)- and (E)-2-methyl-1,5-anti-pentenediols via an allene hydroboration-double-allylboration reaction sequence.  135:9512-9517. 2013
  • Pd(II)-catalyzed phosphorylation of aryl C-H bonds.  135:9322-9325. 2013
  • Pd-catalyzed chemoselective Catellani ortho-arylation of iodopyrroles: rapid total synthesis of rhazinal.  135:9318-9321. 2013
  • Sulfonyl 3-alkynyl pantetheinamides as mechanism-based cross-linkers of acyl carrier protein dehydratase.  135:8846-8849. 2013
  • Broadly applicable methodology for the rapid and dosable small molecule-mediated regulation of transcription factors in human cells.  135:8129-8132. 2013
  • Mechanistic insights into the LsrK kinase required for autoinducer-2 quorum sensing activation.  135:7827-7830. 2013
  • Pd(II)-catalyzed ortho- or meta-C-H olefination of phenol derivatives.  135:7567-7571. 2013
  • Structure and flexibility of nanoscale protein cages designed by symmetric self-assembly.  135:7738-7743. 2013
  • Toward the molecular mechanism(s) by which EGCG treatment remodels mature amyloid fibrils.  135:7503-7510. 2013
  • 2-Bromopalmitate analogues as activity-based probes to explore palmitoyl acyltransferases.  135:7082-7085. 2013
  • Combinatorial generation of complexity by redox enzymes in the chaetoglobosin A biosynthesis.  135:7371-7377. 2013
  • Studies on the Himbert intramolecular arene/allene Diels-Alder cycloaddition. Mechanistic studies and expansion of scope to all-carbon tethers.  135:7339-7348. 2013
  • Enantioselective redox-relay oxidative Heck arylations of acyclic alkenyl alcohols using boronic acids.  135:6830-6833. 2013
  • Sequential C-H functionalization reactions for the enantioselective synthesis of highly functionalized 2,3-dihydrobenzofurans.  135:6774-6777. 2013
  • Diced electrophoresis gel assay for screening enzymes with specified activities.  135:6002-6005. 2013
  • Hydroxyproline-free single composition ABC collagen heterotrimer.  135:6014-6017. 2013
  • Metabolic perturbation of an essential pathway: evaluation of a glycine precursor of coenzyme A.  135:5962-5965. 2013
  • Rational design of fatty acid amide hydrolase inhibitors that act by covalently bonding to two active site residues.  135:6289-6299. 2013
  • Room temperature phosphorescence of metal-free organic materials in amorphous polymer matrices.  135:6325-6329. 2013
  • Aromatic sulfonyl fluorides covalently kinetically stabilize transthyretin to prevent amyloidogenesis while affording a fluorescent conjugate.  135:5656-5668. 2013
  • Enantio- and diastereoselective synthesis of N-acetyl dihydrotetrafibricin methyl ester.  135:5340-5343. 2013
  • Expanding the scope of replicable unnatural DNA: Stepwise optimization of a predominantly hydrophobic base pair 2013
  • A GTP affinity probe for proteomics highlights flexibility in purine nucleotide selectivity.  135:4676-4679. 2013
  • Dynamics of site switching in DNA polymerase.  135:4735-4742. 2013
  • Rhodium-catalyzed conversion of furans to highly functionalized pyrroles.  135:4716-4718. 2013
  • Transannulation of 1-sulfonyl-1,2,3-triazoles with heterocumulenes.  135:4652-4655. 2013
  • A dynamic structural model of expanded RNA CAG repeats: A refined X-ray structure and computational investigations using molecular dynamics and umbrella sampling simulations.  135:3528-3538. 2013
  • Iron(II)-catalyzed intramolecular aminohydroxylation of olefins with functionalized hydroxylamines.  135:3343-3346. 2013
  • Palladium(0)-catalyzed alkynylation of C(sp3)-H bonds.  135:3387-3390. 2013
  • Modulating cocaine vaccine potency through hapten fluorination.  135:2971-2974. 2013
  • Catalytic hydrotrifluoromethylation of unactivated alkenes.  135:2505-2508. 2013
  • Post-polyketide synthase steps in iso-migrastatin biosynthesis, featuring tailoring enzymes with broad substrate specificity.  135:2489-2492. 2013
  • Productive chemical interaction between a bacterial microcolony couple is enhanced by periodic relocation.  135:2242-2247. 2013
  • The revolution and evolution of shotgun proteomics for large-scale proteome analysis.  135:1629-1640. 2013
  • A Pd(0)-mediated indole (macro)cyclization reaction.  135:1600-1606. 2013
  • Pd(II)-catalyzed enantioselective C-H activation/C-O bond formation: synthesis of chiral benzofuranones.  135:1236-1239. 2013
  • Synthesis of (-)-neothiobinupharidine.  135:1209-1212. 2013
  • Iridium-catalyzed enantioselective allylic vinylation.  135:994-997. 2013
  • Self-assembled antibody multimers through peptide nucleic acid conjugation.  135:340-346. 2013
  • Pd(II)-catalyzed C-H iodination using molecular I2 as the sole oxidant.  135:10326-10329. 2013
  • Pd-catalyzed enantioselective C-H iodination: asymmetric synthesis of chiral diarylmethylamines.  135:16344-16347. 2013
  • Small-molecule inducer of β cell proliferation identified by high-throughput screening.  135:1669-1672. 2013
  • "Donor-two-acceptor" dye design: a distinct gateway to NIR fluorescence.  134:20412-20420. 2012
  • Computational design of an α-gliadin peptidase.  134:20513-20520. 2012
  • Iridium-catalyzed enantioselective polyene cyclization.  134:20276-20278. 2012
  • C-C bond formation via copper-catalyzed conjugate addition reactions to enones in water at room temperature..  134:19985-19988. 2012
  • Contact de-electrification of electrostatically charged polymers.  134:20151-20159. 2012
  • Photoreductive uncaging of fluorophore in response to protein oligomers by templated reaction in vitro and in cellulo.  134:20013-20016. 2012
  • Azurin as a protein scaffold for a low-coordinate nonheme iron site with a small-molecule binding pocket.  134:19746-19757. 2012
  • Investigating the dearomative rearrangement of biaryl phosphine-ligated Pd(II) complexes.  134:19922-19934. 2012
  • Synthesis of a potent antimalarial amphilectene.  134:19604-19606. 2012
  • Incorporation of disulfide containing protein modules into multivalent antigenic conjugates: Generation of antibodies against the thrombin-sensitive region of murine protein S.  134:19318-19321. 2012
  • The glmS ribozyme cofactor is a general acid-base catalyst.  134:19043-19049. 2012
  • Ligand-enabled methylene C(sp3)-H bond activation with a Pd(II) catalyst.  134:18570-18572. 2012
  • A tetradentate ligand for the enantioselective Ti(IV)-promoted oxidation of sulfides to sulfoxides: origin of enantioselectivity.  134:17354-17357. 2012
  • Chemical and structural analysis of an antibody folding intermediate trapped during glycan biosynthesis.  134:17554-17563. 2012
  • Concise synthetic approaches for the Laurencia family: formal total syntheses of (±)-laurefucin and (±)-E- and (±)-Z-pinnatifidenyne.  134:17714-17721. 2012
  • Guest-induced, selective formation of isomeric capsules with imperfect walls.  134:17498-17501. 2012
  • Seeing citrulline: Development of a phenylglyoxal-based probe to visualize protein citrullination.  134:17015-17018. 2012
  • Synthesis and biological evaluation of epidithio-, epitetrathio-, and bis-(methylthio)diketopiperazines: synthetic methodology, enantioselective total synthesis of epicoccin G, 8,8'-epi-ent-rostratin B, gliotoxin, gliotoxin G, emethallicin E, and haematocin and discovery of new antiviral and antimalarial agents.  134:17320-17332. 2012
  • Macromolecular crowding and protein stability.  134:16614-16618. 2012
  • Photoinduced phase transfer of luminescent quantum dots to polar and aqueous media..  134:16370-16378. 2012
  • Design strategies for the sequence-based mimicry of side-chain display in protein β-sheets by α/β-peptides.  134:15906-15913. 2012
  • In silica-aided design of a glycan ligand of sialoadhesin for in vivo targeting of macrophages.  134:15696-15699. 2012
  • Stereoselective synthesis of S-linked α(2→8) and α(2→8)/α(2→9) hexasialic acids.  134:16074-16079. 2012
  • Synthesis of alkaloid (-)-205b via stereoselective reductive cross-coupling and intramolecular 3+2 cycloaddition.  134:15237-15240. 2012
  • Arylation of rhodium(II) azavinyl carbenes with boronic acids.  134:14670-14673. 2012
  • Direct arylation/alkylation/magnesiation of benzyl alcohols in the presence of Grignard reagents via Ni-, Fe-, or Co-catalyzed sp3 C-O bond activation.  134:14638-14641. 2012
  • Molecular encapsulation in pyrogallolarene hexamers under nonequilibrium conditions.  134:15000-15009. 2012
  • Self-assembly of highly ordered peptide amphiphile metalloporphyrin arrays.  134:14646-14649. 2012
  • Understanding reactivity and stereoselectivity in palladium-catalyzed diastereoselective sp3 C-H bond activation: intermediate characterization and computational studies.  134:14118-14126. 2012
  • C4-alkoxy-hpd: A potent class of synthetic modulators surpassing nature in al-2 quorum sensing.  134:13562-13564. 2012
  • Fe(III)/NaBH4-mediated free radical hydrofluorination of unactivated alkenes.  134:13588-13591. 2012
  • A designer bleomycin with significantly improved DNA cleavage activity.  134:13501-13509. 2012
  • New insights into the mechanism and an expanded scope of the Fe(III)-mediated vinblastine coupling reaction.  134:13240-13243. 2012
  • Pasteur's tweezers revisited: on the mechanism of attrition-enhanced deracemization and resolution of chiral conglomerate solids.  134:12629-12636. 2012
  • Conformational dynamics and stability of HP35 studied with 2D IR vibrational echoes.  134:12118-12124. 2012
  • Encapsulation of ion pairs in extended, self-assembled structures.  134:11971-11973. 2012
  • Pd(II)-catalyzed ortho trifluoromethylation of arenes and insights into the coordination mode of acidic amide directing groups.  134:11948-11951. 2012
  • Antibody-free reading of the histone code using a simple chemical sensor array.  134:11674-11680. 2012
  • Single-molecule Förster resonance energy transfer reveals an innate fidelity checkpoint in DNA polymerase I.  134:11261-11268. 2012
  • Confirming target engagement for reversible inhibitors in vivo by kinetically tuned activity-based probes.  134:10345-10348. 2012
  • Fully functionalized small-molecule probes for integrated phenotypic screening and target identification.  134:10385-10388. 2012
  • Generation of thiocillin ring size variants by prepeptide gene replacement and in vivo processing by Bacillus cereus.  134:10313-10316. 2012
  • Designing allosteric control into enzymes by chemical rescue of structure.  134:10055-10060. 2012
  • Synthesis of bispecific antibodies using genetically encoded unnatural amino acids.  134:9918-9921. 2012
  • Alpha-glycosylation by d-glucosamine-derived donors: Synthesis of heparosan and heparin analogues that interact with mycobacterial heparin-binding hemagglutinin.  134:8988-8995. 2012
  • Silver(I)-promoted conversion of thioamides to amidines: divergent synthesis of a key series of vancomycin aglycon residue 4 amidines that clarify binding behavior to model ligands.  134:8790-8793. 2012
  • Scalable, divergent synthesis of meroterpenoids via "borono-sclareolide".  134:8432-8435. 2012
  • Alkane lengths determine encapsulation rates and equilibria.  134:8070-8073. 2012
  • An endoglycosidase with alternative glycan specificity allows broadened glycoprotein remodelling.  134:8030-8033. 2012
  • Ligand-dependent exponential amplification of a self-replicating L-RNA enzyme.  134:8050-8053. 2012
  • Total syntheses of anominine and tubingensin a.  134:8078-8081. 2012
  • Enhancement of α-helix mimicry by an α/β-peptide foldamer via incorporation of a dense ionic side-chain array.  134:7317-7320. 2012
  • Generation of candidate ligands for nicotinic acetylcholine receptors via in situ click chemistry with a soluble acetylcholine binding protein template.  134:6732-6740. 2012
  • Degradable conjugates from oxanorbornadiene reagents.  134:6491-6497. 2012
  • Competitive activity-based protein profiling identifies aza-β-lactams as a versatile chemotype for serine hydrolase inhibition.  134:5068-5071. 2012
  • Acyl and silyl group effects in reactivity-based one-pot glycosylation: Synthesis of embryonic stem cell surface carbohydrates lc(4) and iv(2)fuc-lc(4).  134:4549-4552. 2012
  • Design of a bioactive small molecule that targets the myotonic dystrophy type 1 RNA via an RNA motif-ligand database and chemical similarity searching.  134:4731-4742. 2012
  • Mechanistic rationalization of unusual kinetics in Pd-catalyzed C-H olefination.  134:4600-4606. 2012
  • A chemical approach for cell-specific targeting of nanomaterials: Small-molecule-initiated misfolding of nanoparticle corona proteins.  134:4100-4103. 2012
  • Conformations and fluorescence of encapsulated stilbene.  134:4346-4354. 2012
  • Trapping of an intermediate in the reaction catalyzed by flavin-dependent thymidylate synthase.  134:4442-4448. 2012
  • Highly stereoselective synthesis of anti,anti-dipropionate stereotriads: a solution to the long-standing problem of challenging mismatched double asymmetric crotylboration reactions.  134:3925-3931. 2012
  • Quantitative analysis of multisite protein-ligand interactions by NMR: binding of intrinsically disordered p53 transactivation subdomains with the TAZ2 domain of CBP.  134:3792-3803. 2012
  • Exploratory experiments on the chemistry of the "glyoxylate scenario": Formation of ketosugars from dihydroxyfumarate.  134:3577-3589. 2012
  • Selective stabilization of self-assembled hydrogen-bonded molecular capsules through pi-pi interactions.  134:2914-2917. 2012
  • Asymmetric synthesis of dihydroindanes by convergent alkoxide-directed metallacycle-mediated bond formation.  134:2766-2774. 2012
  • Intermolecular Ritter-type C-H amination of unactivated sp3 carbons.  134:2547-2550. 2012
  • Rhodium(II)-catalyzed asymmetric sulfur(VI) reduction of diazo sulfonylamidines.  134:2477-2480. 2012
  • A stereoselective hydroamination transform to access polysubstituted indolizidines.  134:2012-2015. 2012
  • Glycomimetic ligands for the human asialoglycoprotein receptor.  134:1978-1981. 2012
  • A new reagent for direct difluoromethylation.  134:1494-1497. 2012
  • Key mechanistic features of enantioselective c-h bond activation reactions catalyzed by (chiral mono-n-protected amino acid)-pd(ii) complexes.  134:1690-1698. 2012
  • Quantum dots as simultaneous acceptors and donors in time-gated Förster resonance energy transfer relays: characterization and biosensing.  134:1876-1891. 2012
  • Rational design of single-composition ABC collagen heterotrimers.  134:1430-1433. 2012
  • Dehydratase-specific probes for fatty acid and polyketide synthases.  134:769-772. 2012
  • Discrete assembly of synthetic peptide-DNA triplex structures from polyvalent melamine-thymine bifacial recognition.  134:832-835. 2012
  • Oxidative cleavage of cellulose by fungal copper-dependent polysaccharide monooxygenases.  134:890-892. 2012
  • Three-component coupling sequence for the regiospecific synthesis of substituted pyridines.  134:1352-1356. 2012
  • Total synthesis of (-)-fusarisetin A and reassignment of the absolute configuration of its natural counterpart.  134:920-923. 2012
  • Total synthesis of [Psi[C(═S)NH]Tpg4]vancomycin aglycon, [Psi[C(═NH)NH]Tpg4]vancomycin aglycon, and related key compounds: reengineering vancomycin for dual D-Ala-D-Ala and D-Ala-D-Lac binding.  134:1284-1297. 2012
  • Evaluation of diverse α/β-backbone patterns for functional α-helix mimicry: analogues of the Bim BH3 domain.  134:315-323. 2012
  • Improved ruthenium catalysts for Z-selective olefin metathesis.  134:693-699. 2012
  • Pd-catalyzed oxidative ortho-c-h borylation of arenes.  134:134-137. 2012
  • Ribosomal route to small-molecule diversity.  134:418-425. 2012
  • Curtin-Hammett paradigm for stereocontrol in organocatalysis by diarylprolinol ether catalysts.  134:6741-6750. 2012
  • Enantioselective synthesis of anti- and syn-homopropargyl alcohols via chiral Brønsted acid catalyzed asymmetric allenylboration reactions.  134:10947-10952. 2012
  • Organocatalytic, enantioselective intramolecular [6+2] cycloaddition reaction for the formation of tricyclopentanoids and insight on its mechanism from a computational study.  133:20175-20185. 2011
  • A carbohydrate-conjugated deep cavitand permits observation of caviplexes in human serum.  133:19653-19655. 2011
  • Pd(II)-catalyzed enantioselective C-H activation of cyclopropanes.  133:19598-19601. 2011
  • Self-assembling small molecules form nanofibrils that bind procaspase-3 to promote activation.  133:19630-19633. 2011
  • Site-specific labeling of DNA and rna using an efficiently replicated and transcribed class of unnatural base pairs.  133:19878-19888. 2011
  • Ligand-promoted c3-selective arylation of pyridines with pd catalysts: Gram-scale synthesis of (+/-)-preclamol.  133:19090-19093. 2011
  • Total synthesis and structural revision of the piperarborenines via sequential cyclobutane C-H arylation.  133:19076-19079. 2011
  • An active-site guanine participates in glmS ribozyme catalysis in its protonated state.  133:18388-18396. 2011
  • Evidence for in situ catalyst modification during the Pd-catalyzed conversion of aryl triflates to aryl fluorides.  133:18106-18109. 2011
  • Iterative in situ click chemistry assembles a branched capture agent and allosteric inhibitor for akt1.  133:18280-18288. 2011
  • Ligand-accelerated cross-coupling of C(sp2)-H bonds with arylboron reagents.  133:18183-18193. 2011
  • Nucleic acid-templated energy transfer leading to a photorelease reaction and its application to a system displaying a nonlinear response.  133:18110-18113. 2011
  • Synthesis and stereochemical determination of complestatin A and B (neuroprotectin A and B).  133:18495-18502. 2011
  • A practical synthesis of zanamivir phosphonate congeners with potent anti-influenza activity.  133:17959-17965. 2011
  • Synthesis and characterization of the arylomycin lipoglycopeptide antibiotics and the crystallographic analysis of their complex with signal peptidase.  133:17869-17877. 2011
  • Activation of a water-soluble resorcinarene cavitand at the water-phosphocholine micelle interface.  133:17473-17478. 2011
  • Discovery of a protein-metabolite interaction between unsaturated fatty acids and the nuclear receptor Nur77 using a metabolomics approach.  133:17168-17171. 2011
  • Divergent synthesis and chemical reactivity of bicyclic lactone fragments of complex rearranged spongian diterpenes.  133:17494-17503. 2011
  • Theoretical study of hydrogen bonding in homodimers and heterodimers of amide, boronic acid, and carboxylic acid, free and in encapsulation complexes.  133:16977-16985. 2011
  • Atp-stimulated, DNA-mediated redox signaling by xpd, a DNA repair and transcription helicase.  133:16378-16381. 2011
  • Enantioselective total synthesis of aplyviolene.  133:16425-16427. 2011
  • Potent and selective inhibitors of glutathione S-transferase omega 1 that impair cancer drug resistance.  133:16605-16616. 2011
  • Self-assembly and orientation of hydrogen-bonded oligothiophene polymorphs at liquid-membrane-liquid interfaces.  133:16486-16494. 2011
  • Total synthesis and biological evaluation of pederin, psymberin, and highly potent analogs.  133:16668-16679. 2011
  • Translational diffusion of macromolecular assemblies measured using transverse-relaxation-optimized pulsed field gradient NMR.  133:16354-16357. 2011
  • A general strategy for the stereocontrolled preparation of diverse 8- and 9-membered Laurencia-type bromoethers.  133:15898-15901. 2011
  • A multivalent probe for AI-2 quorum-sensing receptors.  133:15934-15937. 2011
  • Incorporation of fluorotyrosines into ribonucleotide reductase using an evolved, polyspecific aminoacyl-tRNA synthetase.  133:15942-15945. 2011
  • Dual catalysis in enantioselective oxidopyrylium-based [5 + 2] cycloadditions.  133:14578-14581. 2011
  • Enantioselective total syntheses of (-)-palau'amine, (-)-axinellamines, and (-)-massadines.  133:14710-14726. 2011
  • A redesigned vancomycin engineered for dual D-Ala-D-ala And D-Ala-D-Lac binding exhibits potent antimicrobial activity against vancomycin-resistant bacteria.  133:13946-13949. 2011
  • Pd(ii)-catalyzed para-selective c-h arylation of monosubstituted arenes.  133:13864-13867. 2011
  • Scalable, stereocontrolled total syntheses of (±)-axinellamines A and B.  133:13922-13925. 2011
  • Synthesis and characterization of a series of highly fluorogenic substrates for glutathione transferases, a general strategy.  133:14109-14119. 2011
  • Lyotropic liquid crystals formed from ACHC-rich β-peptides.  133:13604-13613. 2011
  • Highly efficient hydrogen-bonding catalysis of the diels-alder reaction of 3-vinylindoles and methyleneindolinones provides carbazolespirooxindole skeletons.  133:12354-12357. 2011
  • Inverse electron demand Diels-Alder reactions of 1,2,3-triazines: Pronounced substituent effects on reactivity and cycloaddition scope.  133:12285-12292. 2011
  • A substrate-free activity-based protein profiling screen for the discovery of selective PREPL inhibitors.  133:11665-11674. 2011
  • Bent alkanes in a new thiourea-containing capsule.  133:10682-10684. 2011
  • Catalytic asymmetric C-H insertions of rhodium(II) azavinyl carbenes.  133:10352-10355. 2011
  • Spatiotemporal multicolor labeling of individual cells using peptide-functionalized quantum dots and mixed delivery techniques.  133:10482-10489. 2011
  • Broad distribution of energetically important contacts across an extended protein interface.  133:10038-10041. 2011
  • Defining the rna internal loops preferred by benzimidazole derivatives via 2D combinatorial screening and computational analysis.  133:10111-10118. 2011
  • Design, synthesis, and validation of a β-turn mimetic library targeting protein-protein and peptide-receptor interactions.  133:10184-10194. 2011
  • Convergent and stereodivergent synthesis of complex 1-aza-7-oxabicyclo 2.2.1 heptanes.  133:9216-9219. 2011
  • Functional virus-based polymer-protein nanoparticles by atom transfer radical polymerization.  133:9242-9245. 2011
  • Multifunctional compact zwitterionic ligands for preparing robust biocompatible semiconductor quantum dots and gold nanoparticles.  133:9480-9496. 2011
  • A concise, stereocontrolled total synthesis of rippertenol.  133:8850-8853. 2011
  • Mechanistic rationalization of organocatalyzed conjugate addition of linear aldehydes to nitro-olefins.  133:8822-8825. 2011
  • Molecular recognition of insulin by a synthetic receptor.  133:8810-8813. 2011
  • Enantioselective dichlorination of allylic alcohols.  133:8134-8137. 2011
  • Total synthesis of epicoccin G.  133:8150-8153. 2011
  • Pd-catalyzed intermolecular C-H amination with alkylamines.  133:7652-7655. 2011
  • Scalable synthesis of cortistatin A and related structures.  133:8014-8027. 2011
  • Divergent c-h functionalizations directed by sulfonamide pharmacophores: Late-stage diversification as a tool for drug discovery.  133:7222-7228. 2011
  • Ligand-promoted c-3 selective c-h olefination of pyridines with pd catalysts.  133:6964-6967. 2011
  • Impact of distinct chemical structures for the development of a methamphetamine vaccine.  133:6587-6595. 2011
  • Temperature dependent equilibrium native to unfolded protein dynamics and properties observed with IR absorption and 2D IR vibrational echo experiments.  133:6681-6691. 2011
  • Addressing the stereochemistry of complex organic molecules by density functional theory-NMR: vannusal B in retrospective.  133:6072-6077. 2011
  • Enantioconvergent hydroboration of a racemic allene: enantioselective synthesis of (E)-δ-stannyl-anti-homoallylic alcohols via aldehyde crotylboration.  133:5744-5747. 2011
  • Highly convergent total synthesis of (+)-lithospermic acid via a late-stage intermolecular C-H olefination.  133:5767-5769. 2011
  • Monoalkylglycerol ether lipids promote adipogenesis.  133:5178-5181. 2011
  • Positive and negative design leads to compositional control in AAB collagen heterotrimers.  133:5432-5443. 2011
  • Core-structure-motivated design of a phosphine-catalyzed 3+2 cycloaddition reaction: Enantioselective syntheses of spirocyclopenteneoxindoles.  133:4672-4675. 2011
  • Hairpin folding behavior of mixed α/β-peptides in aqueous solution.  133:4246-4249. 2011
  • Fluoride-mediated capture of a noncovalent bound state of a reversible covalent enzyme inhibitor: X-ray crystallographic analysis of an exceptionally potent α-ketoheterocycle inhibitor of fatty acid amide hydrolase.  133:4092-4100. 2011
  • Protein dynamics in cytochrome P450 molecular recognition and substrate specificity using 2D IR vibrational echo spectroscopy.  133:3995-4004. 2011
  • Synthesis and molecular modeling provide insight into a Pseudomonas aeruginosa quorum sensing conundrum.  133:3840-3842. 2011
  • Unraveling the mechanism of cascade reactions of zincke aldehydes.  133:3895-3905. 2011
  • Practical C-H functionalization of quinones with boronic acids.  133:3292-3295. 2011
  • Synthesis of a trimeric gp120 epitope mimic conjugated to a t-helper peptide to improve antigenicity.  133:3230-3233. 2011
  • An isothermal system that couples ligand-dependent catalysis to ligand-independent exponential amplification.  133:3191-3197. 2011
  • Stepwise synthesis of giant unilamellar vesicles on a microfluidic assembly line.  133:2798-2800. 2011
  • Combinatorially inducible RNA interference triggered by chemically modified oligonucleotides.  133:2783-2788. 2011
  • Light-induced conformational change and product release in DNA repair by (6-4) photolyase.  133:2183-2191. 2011
  • Development of proneurogenic, neuroprotective small molecules.  133:1428-1437. 2011
  • Metal-substituted protein MRI contrast agents engineered for enhanced relaxivity and ligand sensitivity.  133:649-651. 2011
  • Enzymatic de novo pyrimidine nucleotide synthesis.  133:297-304. 2011
  • Synthesis of the wxyza ' domain of maitotoxin.  133:220-226. 2011
  • Total synthesis of the Bacteroides fragilis zwitterionic polysaccharide A1 repeating unit.  133:102-107. 2011
  • Boronic acid hydrogen bonding in encapsulation complexes.  133:9689-9691. 2011
  • Core-clickable peg-branch-azide bivalent-bottle-brush polymers by romp: Grafting-through and clicking-to.  133:559-566. 2011
  • Synthesis of the C′D′E′F′ domain of maitotoxin.  133:214-219. 2011
  • Self-assembled quantum dot-sensitized multivalent DNA photonic wires.  132:18177-18190. 2010
  • Pd(II)-catalyzed carbonylation of C(sp3)-H bonds: a new entry to 1,4-dicarbonyl compounds.  132:17378-17380. 2010
  • Nosa catalyzing carboxyl-terminal amide formation in nosiheptide maturation via an enamine dealkylation on the serine-extended precursor peptide.  132:16324-16326. 2010
  • A stilbene that binds selectively to transthyretin in cells and remains dark until it undergoes a chemoselective reaction to create a bright blue fluorescent conjugate.  132:16043-16051. 2010
  • Context-dependent effects of asparagine glycosylation on Pin WW folding kinetics and thermodynamics.  132:15359-15367. 2010
  • Unusual inverse temperature dependence on reaction rate in the asymmetric autocatalytic alkylation of pyrimidyl aldehydes.  132:15104-15107. 2010
  • Differential receptor binding affinities of influenza hemagglutinins on glycan arrays.  132:14849-14856. 2010
  • Tailored ligand acceleration of the Cu-catalyzed azide-alkyne cycloaddition reaction: practical and mechanistic implications.  132:14570-14576. 2010
  • Ligand-accelerated C-H activation reactions: evidence for a switch of mechanism.  132:14137-14151. 2010
  • Simple reagents for direct halonium-induced polyene cyclizations.  132:14303-14314. 2010
  • Selective recognition and extraction of the uranyl ion.  132:13572-13574. 2010
  • Synthesis and characterization of a cyclobutane duocarmycin derivative incorporating the 1,2,10,11-tetrahydro-9H-cyclobuta[c]benzo[e]indol-4-one (CbBI) alkylation subunit.  132:13936-13940. 2010
  • A bacteriophage-based platform for rapid trace detection of proteases.  132:13126-13128. 2010
  • Asymmetric total synthesis of vindorosine, vindoline, and key vinblastine analogues.  132:13533-13544. 2010
  • Direct C-H arylation of electron-deficient heterocycles with arylboronic acids.  132:13194-13196. 2010
  • Glycan array on aluminum oxide-coated glass slides through phosphonate chemistry.  132:13371-13380. 2010
  • Nickel-catalyzed alkenylative cross-coupling reaction of alkyl sulfides.  132:13117-13119. 2010
  • Mri detection of vegfr2 in vivo using a low molecular weight peptoid-(gd)(8)-dendron for targeting.  132:12829-12831. 2010
  • Acceleration of nucleophilic ch activation by strongly basic solvents.  132:12542-12545. 2010
  • Enediyne antitumor antibiotic maduropeptin biosynthesis featuring a c-methyltransferase that acts on a coa-tethered aromatic substrate.  132:12534-12536. 2010
  • Pd(ii)-catalyzed hydroxyl-directed c-h activation/c-o cyclization: Expedient construction of dihydrobenzofurans.  132:12203-12205. 2010
  • Structural consequences of β-amino acid preorganization in a self-assembling α/β-peptide: fundamental studies of foldameric helix bundles.  132:12378-12387. 2010
  • Conserved binding mode of human beta(2) adrenergic receptor inverse agonists and antagonist revealed by X-ray crystallography.  132:11443-11445. 2010
  • Nitric oxide synthase stabilizes the tetrahydrobiopterin cofactor radical by controlling its protonation state.  132:11812-11823. 2010
  • Total synthesis of lehualide b by allylic alcohol-alkyne reductive cross-coupling.  132:11422-11424. 2010
  • Mechanism of the enantioselective oxidation of racemic secondary alcohols catalyzed by chiral Mn(III)-salen complexes.  132:11165-11170. 2010
  • Total synthesis of sporolide B and 9-epi-sporolide B.  132:11350-11363. 2010
  • Iron-catalyzed Suzuki-Miyaura coupling of alkyl halides.  132:10674-10676. 2010
  • Rapid visualization and large-scale profiling of bacterial lipoproteins with chemical reporters.  132:10628-10629. 2010
  • Molecular analysis of carbohydrate-antibody interactions: case study using a Bacillus anthracis tetrasaccharide..  132:10239-10241. 2010
  • Pd-catalyzed O-arylation of ethyl acetohydroximate: synthesis of O-arylhydroxylamines and substituted benzofurans.  132:9990-9991. 2010
  • Rapid covalent ligation of fluorescent peptides to water solubilized quantum dots.  132:10027-10033. 2010
  • Supramolecular control of fluorescence through reversible encapsulation.  132:9984-9985. 2010
  • Chemoselective reductive cross-coupling of 1,5-diene-3-ols with alkynes: A facile entry to stereodefined skipped trienes.  132:9576-9578. 2010
  • Multidentate poly(ethylene glycol) ligands provide colloidal stability to semiconductor and metallic nanocrystals in extreme conditions.  132:9804-9813. 2010
  • Synthesis of the QRSTU domain of maitotoxin and its 85-epi- and 86-epi-diastereoisomers.  132:9900-9907. 2010
  • Gold-catalyzed three-component coupling: oxidative oxyarylation of alkenes.  132:8885-8887. 2010
  • Intramolecular 1+2 and 3+2 cycloaddition reactions of cyclopropenone ketals.  132:8527-8529. 2010
  • Total synthesis and evaluation of a key series of C5-substituted vinblastine derivatives.  132:8489-8495. 2010
  • Total synthesis of enantiopure phalarine via a stereospecific Pictet-Spengler reaction: traceless transfer of chirality from L-tryptophan.  132:8506-8512. 2010
  • Enantioselective synthesis of (E)-delta-stannyl homoallylic alcohols via aldehyde allylboration using alpha-stannylallylboranes generated by allene hydroboration followed by a highly diastereoselective 1,3-boratropic shift.  132:7881-7883. 2010
  • Total synthesis of englerin a.  132:8219-8222. 2010
  • Polyketide assembly by alkene-alkyne reductive cross-coupling: Spiroketals through the union of homoallylic alcohols.  132:7602-7604. 2010
  • Total synthesis of complestatin: development of a Pd(0)-mediated indole annulation for macrocyclization.  132:7776-7783. 2010
  • Unusual reversal of enantioselectivity in the proline-mediated alpha-amination of aldehydes induced by tertiary amine additives.  132:7598-7899. 2010
  • Recognition of the ring-opened state of proliferating cell nuclear antigen by replication factor c promotes eukaryotic clamp-loading.  132:7372-7378. 2010
  • Total synthesis and biological evaluation of the resveratrol-derived polyphenol natural products hopeanol and hopeahainol a.  132:7540-7548. 2010
  • Scalable total syntheses of N-linked tryptamine dimers by direct indole-aniline coupling: Psychotrimine and kapakahines B and F.  132:7119-7137. 2010
  • Total synthesis and structural revision of vannusals A and B: synthesis of the originally assigned structure of vannusal B.  132:7138-7152. 2010
  • Total synthesis and structural revision of vannusals A and B: synthesis of the true structures of vannusals A and B.  132:7153-7176. 2010
  • Functional characterization of ttnd and ttnf, unveiling new insights into tautomycetin biosynthesis.  132:6663-6671. 2010
  • Synthesis of the ABCDEFG ring system of maitotoxin.  132:6855-6861. 2010
  • Dimeric quinidine-catalyzed enantioselective aminooxygenation of oxindoles: An organocatalytic approach to 3-hydroxyoxindole derivatives.  132:5574-5575. 2010
  • Pd(II)-catalyzed hydroxyl-directed C-H olefination enabled by monoprotected amino acid ligands.  132:5916-5921. 2010
  • Ru-porphyrin protein scaffolds for sensing o(2).  132:5582-5583. 2010
  • Pterin-centered radical as a mechanistic probe of the second step of nitric oxide synthase.  132:5105-5113. 2010
  • Total synthesis of (+/-)- and (-)-actinophyllic acid.  132:4894-4906. 2010
  • Expanding the chemistry of DNA for in vitro selection.  132:4141-4151. 2010
  • Bioorthogonal chemical reporters for monitoring protein acetylation.  132:3640-3641. 2010
  • Enzyme-catalyzed transfer of a ketone group from an S-adenosylmethionine analogue: a tool for the functional analysis of methyltransferases.  132:3642-3643. 2010
  • Expanding the dipeptidyl peptidase 4-regulated peptidome via an optimized peptidomics platform.  132:3819-3830. 2010
  • Pd(II)-catalyzed olefination of sp(3) C-H bonds.  132:3680-3681. 2010
  • Pd(ii)-catalyzed ortho-trifluoromethylation of arenes using tfa as a promoter.  132:3648-3649. 2010
  • Total synthesis of echinopines a and b.  132:3815-3818. 2010
  • Activity-based probes that target functional subclasses of phospholipases in proteomes.  132:3264-3265. 2010
  • Selective assembly of a high stability AAB collagen heterotrimer.  132:3242-3243. 2010
  • Botulinum neurotoxin a protease: Discovery of natural product exosite inhibitors.  132:2868-2869. 2010
  • Self-assembling multidomain peptide hydrogels: designed susceptibility to enzymatic cleavage allows enhanced cell migration and spreading.  132:3217-3223. 2010
  • Total synthesis of (+)-fendleridine (aspidoalbidine) and (+)-1-acetylaspidoalbidine.  132:3009-3012. 2010
  • A concise enantioselective synthesis of the chlorosulfolipid malhamensilipin A.  132:2542-2543. 2010
  • Easy access to a family of polymer catalysts from modular star polymers.  132:2570-2572. 2010
  • Synthesis and reactivity of rhodium(ii) n-triflyl azavinyl carbenes.  132:2510-2511. 2010
  • Total synthesis, assignment of the relative and absolute stereochemistry, and structural reassignment of phostriecin (aka Sultriecin).  132:2157-2159. 2010
  • Visualizing the reaction coordinate of an O-GlcNAc hydrolase.  132:1807-1809. 2010
  • Tyrosine bioconjugation through aqueous ene-type reactions: A click-like reaction for tyrosine.  132:1523-1525. 2010
  • A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity.  132:1359-1370. 2010
  • Total synthesis of the antimitotic bicyclic peptide celogentin C.  132:1159-1171. 2010
  • Pd(II)-catalyzed enantioselective C-H olefination of diphenylacetic acids.  132:460-461. 2010
  • Synthetic applications of Pd(II)-catalyzed C-H carboxylation and mechanistic insights: expedient routes to anthranilic acids, oxazolinones, and quinazolinones.  132:686-693. 2010
  • Cu(I)-amido complexes in the Ullmann reaction: reactions of Cu(I)-amido complexes with iodoarenes with and without autocatalysis by CuI.  132:15860-15863. 2010
  • Asymmetric total synthesis of vindoline.  132:3685-3687. 2010
  • Biocompatible copper(I) catalysts for in vivo imaging of glycans.  132:16893-16899. 2010
  • Modulating heme redox potential through protein-induced porphyrin distortion.  132:12794-12795. 2010
  • Direct observation of an enamine intermediate in amine catalysis.  131:18206-18207. 2009
  • NMR characterization of membrane protein-detergent micelle solutions by use of microcoil equipment.  131:18450-18456. 2009
  • Rhodium-catalyzed enantioselective cyclopropanation of olefins with N-sulfonyl 1,2,3-triazoles.  131:18034-18035. 2009
  • A convergent stereoselective synthesis of quinolizidines and indolizidines: Chemoselective coupling of 2-hydroxymethyl-substituted allylic silanes with imines.  131:17548-17549. 2009
  • Buckyballs meet viral nanoparticles: Candidates for biomedicine.  131:17093-17095. 2009
  • Controlling the specificity of modularly assembled small molecules for RNA via ligand module spacing: Targeting the RNAs that cause myotonic muscular dystrophy.  131:17464-17472. 2009
  • Product protection, the key to developing high performance methane selective oxidation catalysts.  131:17110-17115. 2009
  • Total synthesis of vinigrol.  131:17066-17067. 2009
  • Lipid membrane adhesion and fusion driven by designed, minimally multivalent hydrogen-bonding lipids.  131:16919-16926. 2009
  • Total synthesis of platensimycin and related natural products.  131:16905-16918. 2009
  • An antibody-recruiting small molecule that targets HIV gp120.  131:16392-+. 2009
  • Characterization of the sgcf epoxide hydrolase supporting an (r)-vicinal diol intermediate for enediyne antitumor antibiotic c-1027 biosynthesis.  131:16410-16417. 2009
  • Tandem application of virtual screening and NMR experiments in the discovery of brand new DNA quadruplex groove binders.  131:16336-16337. 2009
  • Total synthesis of chloropeptin II (complestatin) and chloropeptin I.  131:16036-16038. 2009
  • Revisiting AI-2 quorum sensing inhibitors: Direct comparison of alkyl-DPD analogues and a natural product fimbrolide.  131:15584-15585. 2009
  • Total syntheses of (+/-)-platencin and (-)-platencin.  131:15909-15917. 2009
  • Ring-closing metathesis of allylsilanes/electrophilic desilylation to prepare exo-methylidenecycloalkanes. Short syntheses of teucladiol and poitediol.  131:15090-15091. 2009
  • Enantioselective synthesis of 2-methyl-1,2-syn- and 2-methyl-1,2-anti-3-butenediols via allene hydroboration-aldehyde allylboration reaction sequences.  131:14602-14603. 2009
  • PCR with an expanded genetic alphabet.  131:14620-14621. 2009
  • Pd(ii)-catalyzed hydroxylation of arenes with 1 atm of o(2) or air.  131:14654-14655. 2009
  • Total synthesis and biological evaluation of (+)- and (-)-bisanthraquinone antibiotic BE-43472B and related compounds.  131:14812-14826. 2009
  • Defining the mode of action of tetramic acid antibacterials derived from Pseudomonas aeruginosa quorum sensing signals.  131:14473-14479. 2009
  • EPR and ENDOR characterization of the reactive intermediates in the generation of NO by cryoreduced oxy-nitric oxide synthase from Geobacillus stearothermophilus.  131:14493-14507. 2009
  • Enzymatic synthesis and structural characterization of 13C, 15N-poly(ADP-ribose).  131:14571-14578. 2009
  • Stereoselective synthesis of gamma-substituted (Z)-allylic boranes via kinetically controlled hydroboration of allenes with 10-TMS-9-borabicyclo[3.3.2]decane.  131:14174-14175. 2009
  • Conditional RNA interference mediated by allosteric ribozyme.  131:13906-13907. 2009
  • Microfluidic device for single-molecule experiments with enhanced photostability.  131:13610-13612. 2009
  • Organocatalytic synthesis of spiro[pyrrolidin-3,3'-oxindoles] with high enantiopurity and structural diversity.  131:13819-13825. 2009
  • "Too small, too big, and just right" - optical sensing of molecular conformations in self-assembled capsules.  131:13190-13191. 2009
  • Probing synergy between two catalytic strategies in the glycoside hydrolase O-GlcNAcase using multiple linear free energy relationships.  131:13415-13422. 2009
  • Genetic incorporation of a small, environmentally sensitive, fluorescent probe into proteins in Saccharomyces cerevisiae.  131:12921-12923. 2009
  • Synthesis at the interface of chemistry and biology.  131:12497-12515. 2009
  • Buckled membranes in mixed-valence ionic amphiphile vesicles.  131:12030-12031. 2009
  • Relaxation dynamics of Pseudomonas aeruginosa Re(I)(CO)3(alpha-diimine)(HisX)(+) (X = 83, 107, 109, 124, 126)Cu(II) azurins.  131:11788-11800. 2009
  • Transition-state charge transfer reveals electrophilic, ambiphilic, and nucleophilic carbon-hydrogen bond activation.  131:11686-11688. 2009
  • Pd(II)-catalyzed amination of C-H bonds using single-electron or two-electron oxidants.  131:10806-10807. 2009
  • A suite of activity-based probes for human cytochrome P450 enzymes.  131:10692-10700. 2009
  • Binding and inactivation mechanism of a humanized fatty acid amide hydrolase by alpha-ketoheterocycle inhibitors revealed from cocrystal structures.  131:10497-10506. 2009
  • Total synthesis and biological evaluation of cortistatins a and j and analogues thereof.  131:10587-10597. 2009
  • An α/β-peptide helix bundle with a pure β3-amino acid core and a distinctive quaternary structure.  131:9860-9861. 2009
  • Pd(0)/PR(3)-catalzed intermolecular arylation of sp(3) C-H bonds.  131:9886-9887. 2009
  • Thiol-selective fluorogenic probes for labeling and release.  131:9986-9994. 2009
  • Evolution of proteins with genetically encoded "chemical warheads".  131:9616-9617. 2009
  • Possible origin of electronic effects in rh(i)-catalyzed enantioselective hydrogenation.  131:9604-9605. 2009
  • Rational design of ligands targeting triplet repeating transcripts that cause RNA dominant disease: Application to myotonic muscular dystrophy type 1 and spinocerebellar ataxia type 3.  131:9767-9779. 2009
  • Probing the dynamics of the p1 helix within the tetrahymena group i intron.  131:9571-9578. 2009
  • Consecutive intramolecular hydroamination/asymmetric transfer hydrogenation under relay catalysis of an achiral gold complex/chiral Bronsted acid binary system.  131:9182-+. 2009
  • Escherichia coli allows efficient modular incorporation of newly isolated quinomycin biosynthetic enzyme into echinomycin biosynthetic pathway for rational design and synthesis of potent antibiotic unnatural natural product.  131:9347-9353. 2009
  • Scalable total synthesis and biological evaluation of haouamine a and its atropisomer.  131:9172-9173. 2009
  • Universal translators for nucleic acid diagnosis.  131:9368-9377. 2009
  • Thiourea-catalyzed highly enantio- and diastereoselective additions of oxindoles to nitroolefins: Application to the formal synthesis of (+)-physostigmine.  131:8758-8759. 2009
  • Concise synthesis of iminocyclitols via petasis-type aminocyclization.  131:8352-8353. 2009
  • Complex polycyclic lactams from pericyclic cascade reactions of Zincke aldehydes.  131:7546-7547. 2009
  • Relative stereochemistry determination and synthesis of the major chlorosulfolipid from Ochromonas danica.  131:7570-7572. 2009
  • Mixing and matching detergents for membrane protein NMR structure determination.  131:7320-7326. 2009
  • Probing the folding transition state structure of the villin headpiece subdomain via side chain and backbone mutagenesis.  131:7470-7476. 2009
  • Recognition and organocatalysis with a synthetic cavitand receptor.  131:7402-7410. 2009
  • Bifunctional acyltransferase/decarboxylase lnmk as the missing link for beta-alkylation in polyketide biosynthesis.  131:6900-6901. 2009
  • Prediction of the rotational tumbling time for proteins with disordered segments.  131:6814-6821. 2009
  • Total synthesis of (-)-acutumine.  131:6674-6675. 2009
  • Enantiospecific total syntheses of kapakahines B and F.  131:6360-6361. 2009
  • Imaging of mRNA in live cells using nucleic acid-templated reduction of azidorhodamine probes.  131:6492-6497. 2009
  • Direct observation of ligand dynamics in cytochrome c.  131:6054-6055. 2009
  • A short and efficient synthesis of (-)-7-methylomuralide, a potent proteasome inhibitor.  131:5746-5747. 2009
  • Direct observation of structural heterogeneity in a β-sheet.  131:5726-5727. 2009
  • Enantioselective total synthesis of (-)-napyradiomycin A1 via asymmetric chlorination of an isolated olefin.  131:5744-5745. 2009
  • Selective toxin sequestrants for the treatment of bacterial infections.  131:5760-5762. 2009
  • Design, synthesis, and evaluation of an α-helix mimetic library targeting protein-protein interactions.  131:5564-5572. 2009
  • Toward homogeneous erythropoietin: chemical synthesis of the Ala1-Gly28 glycopeptide domain by "alanine" ligation.  131:5438-5443. 2009
  • Identification of an overabundant cholesterol precursor in hepatitis B virus replicating cells by untargeted lipid metabolite profiling.  131:5030-5031. 2009
  • Pd(ii)-catalyzed olefination of electron-deficient arenes using 2,6-dialkylpyridine ligands.  131:5072-5074. 2009
  • Transcription of an expanded genetic alphabet.  131:5046-5047. 2009
  • Chiral Brønsted acid-catalyzed enantioselective alpha-hydroxylation of beta-dicarbonyl compounds.  131:4562-4563. 2009
  • Total synthesis of vinblastine, vincristine, related natural products, and key structural analogues.  131:4904-4916. 2009
  • Efficient access to the core of the Strychnos, Aspidosperma and Iboga alkaloids. A short synthesis of norfluorocurarine.  131:3472-3473. 2009
  • New synthetic technologies for the construction of heterocycles and tryptamines.  131:3690-3699. 2009
  • Discovery of inhibitors of aberrant gene transcription from libraries of DNA binding molecules: Inhibition of LEF-1-mediated gene transcription and oncogenic transformation.  131:3342-3348. 2009
  • Stereoselective synthesis and osteogenic activity of subglutinols A and B.  131:3192-3194. 2009
  • Synthesis of S-linked alpha(2-->9) octasialic acid via exclusive alpha S-glycosidic bond formation.  131:3138-3139. 2009
  • Design, synthesis, biological evaluation, and structural characterization of potent histone deacetylase inhibitors based on cyclic alpha/beta-tetrapeptide architectures.  131:3033-3041. 2009
  • Genetic incorporation of a metal-ion chelating amino acid into proteins as a biophysical probe.  131:2481-2483. 2009
  • Invariant polymorphism in virus capsid assembly.  131:2606-2614. 2009
  • Oxy-functionalization of nucleophilic rhenium(I) metal carbon bonds catalyzed by selenium(IV).  131:2466-2468. 2009
  • Pseudo-capsule assemblies characterized by (19)f NMR techniques.  131:2440-2441. 2009
  • In vitro imaging and in vivo liver targeting with carbohydrate capped quantum dots.  131:2110-2112. 2009
  • Explorations into neolignan biosynthesis: concise total syntheses of helicterin B, helisorin, and helisterculin A from a common intermediate.  131:1745-1752. 2009
  • Total synthesis of diverse carbogenic complexity within the resveratrol class from a common building block.  131:1753-1765. 2009
  • Lactimidomycin, iso-migrastatin and related glutarimide-containing 12-membered macrolides are extremely potent inhibitors of cell migration.  131:1370-1371. 2009
  • Total synthesis and structure elucidation of (+)-phorbasin c.  131:1392-1393. 2009
  • Boron nitride nanotubes are noncytotoxic and can be functionalized for interaction with proteins and cells.  131:890-891. 2009
  • Total synthesis and evaluation of iso-duocarmycin SA and iso-yatakemycin.  131:1187-1194. 2009
  • Identification of a new endogenous metabolite and the characterization of its protein interactions through an immobilization approach.  131:378-386. 2009
  • The second step of the nitric oxide synthase reaction: Evidence for ferric-peroxo as the active oxidant.  131:297-305. 2009
  • Enantioselective intramolecular Friedel−Crafts-type α-arylation of aldehydes.  131:2086-2087. 2009
  • Optimization of an unnatural base pair toward natural-like replication.  131:3246-3252. 2009
  • Versatile Pd(OTf)2 x 2 H2O-catalyzed ortho-fluorination using NMP as a promoter.  131:7520-7521. 2009
  • A general and efficient method for the site-specific dual-labeling of proteins for single molecule fluorescence resonance energy transfer.  130:17664-17665. 2008
  • Enantiospecific total synthesis of the hapalindoles, fischerindoles, and welwitindolinones via a redox economic approach.  130:17938-17954. 2008
  • Versatile Pd(II)-catalyzed C-H activation/aryl-aryl coupling of benzoic and phenyl acetic acids.  130:17676-17677. 2008
  • Conversion of allylic alcohols to stereodefined trisubstituted alkenes: A complementary process to the claisen rearrangement.  130:16870-16872. 2008
  • Self-assembling peptide coatings designed for highly luminescent suspension of single-walled carbon nanotubes.  130:17134-17140. 2008
  • An additional spirocyclization for duocarmycin SA.  130:16521-16523. 2008
  • Application of affinity selection/mass spectrometry to determine the structural isomer of parnafungins responsible for binding polyadenosine polymerase.  130:16704-16710. 2008
  • Interactions between redox complexes and semiconductor quantum dots coupled via a peptide bridge.  130:16745-16756. 2008
  • Total syntheses of (+/-)-massadine and massadine chloride.  130:16490-16491. 2008
  • Engineering complex riboswitch regulation by dual genetic selection.  130:16310-16315. 2008
  • Total syntheses of (+)-tedanolide and (+)-13-deoxytedanolide.  130:16407-16416. 2008
  • Targeting large kinase active site with rigid, bulky octahedral ruthenium complexes.  130:15764-5. 2008
  • Evolution of solid phase homochirality for a proteinogenic amino acid.  130:15274-15275. 2008
  • A concise asymmetric total synthesis of aspidophytine.  130:14942-14943. 2008
  • Rhodium-catalyzed transannulation of 1,2,3-triazoles with nitriles.  130:14972-14974. 2008
  • The structure of a TNA-TNA complex in solution: NMR study of the octamer duplex derived from alpha-(L)-threofuranosyl-(3 '-2 ')-CGAATTCG.  130:15105-15115. 2008
  • Toward a chemical mechanism of proton pumping by the B-type cytochrome c oxidases: application of density functional theory to cytochrome ba(3) of Thermus thermophilus.  130:15002-15021. 2008
  • Intra- and intermembrane pairwise molecular recognition between synthetic hydrogen-bonding phospholipids.  130:14456-14458. 2008
  • Unnatural substrate repertoire of a, b, and x family DNA polymerases.  130:14872-14882. 2008
  • A global metabolite profiling approach to identify protein-metabolite interactions.  130:14111-14113. 2008
  • Synthesis of 1,2- and 1,3-dicarboxylic acids via Pd(II)-catalyzed carboxylation of aryl and vinyl C-H bonds.  130:14082-14083. 2008
  • Synthesis of β-, γ-, and δ-Lactams via Pd(II)-catalyzed C−H activation reaction.  130:14058-14059. 2008
  • Self-assembly of α-helical coiled coil nanofibers.  130:13691-13695. 2008
  • Biosynthesis of a site-specific DNA cleaving protein.  130:13194-13195. 2008
  • Design, synthesis, and biological evaluation of platensimycin analogues with varying degrees of molecular complexity.  130:13110-13119. 2008
  • Quantitative microarray analysis of intact glycolipid-CD1d interaction and correlation with cell-based cytokine production.  130:12348-12354. 2008
  • Stereoselective dichlorination of allylic alcohol derivatives to access key stereochemical arrays of the chlorosulfolipids.  130:12514-12518. 2008
  • Time-resolved dimerization of a PAS-LOV protein measured with photocoupled small angle X-ray scattering.  130:12226-12227. 2008
  • Total synthesis of chlorofusin, its seven chromophore diastereomers, and key partial structures.  130:12355-12369. 2008
  • Reaction of isonitriles with carboxylic acids in a cavitand: Observation of elusive isoimide intermediates.  130:11850-11851. 2008
  • Sugar-assisted glycopeptide ligation with complex oligosaccharides: Scope and limitations.  130:11945-11952. 2008
  • Enantioselective total syntheses of nankakurines A and B: confirmation of structure and establishment of absolute configuration.  130:11297-11299. 2008
  • Intermolecular enolate heterocoupling: Scope, mechanism, and application.  130:11546-11560. 2008
  • Origins of enhanced proton transport in the Y7F mutant of human carbonic anhydrase II.  130:11399-11408. 2008
  • Solution phase measurement of both weak sigma and C-H center dot center dot center dot X- hydrogen bonding interactions in synthetic anion receptors.  130:10895-10897. 2008
  • Total synthesis of (+/-)-psychotrimine.  130:10886-10887. 2008
  • Total synthesis, revised structure, and biological evaluation of biyouyanagin A and analogues thereof.  130:11114-11121. 2008
  • Two-dimensional combinatorial screening identifies specific aminoglycoside - RNA internal loop partners.  130:11185-11194. 2008
  • Chemical synthesis and biological evaluation of palmerolide a analogues.  130:10019-10023. 2008
  • An unexpected switch in the modulation of AI-2-based quorum sensing discovered through synthetic 4,5-dihydroxy-2,3-pentanedione analogues.  130:9200-9201. 2008
  • In vivo incorporation of unnatural amino acids to probe structure, dynamics, and ligand binding in a large protein by nuclear magnetic resonance spectroscopy.  130:9268-9281. 2008
  • Total synthesis and molecular target of largazole, a histone deacetylase inhibitor.  130:8455-8459. 2008
  • Reaction of carboxylic acids and isonitriles in small spaces.  130:7810-7811. 2008
  • Bifunctional CD22 ligands use multimeric immunoglobulins as protein scaffolds in assembly of immune complexes on B cells.  130:7736-7745. 2008
  • Stereocontrolled synthesis of Z-dienes via an unexpected pericyclic cascade rearrangement of 5-amino-2,4-pentadienals.  130:7560-7561. 2008
  • Total synthesis of (+/-)-actinophyllic acid.  130:7568-7569. 2008
  • 1,3-diol synthesis via controlled, radical-mediated C-H functionalization.  130:7247-7249. 2008
  • Chemical synthesis of the GHIJKLMNO ring system of maitotoxin.  130:7466-7476. 2008
  • Microscale NMR screening of new detergents for membrane protein structural biology.  130:7357-7363. 2008
  • Synthesis of (+)-cortistatin A.  130:7241-7243. 2008
  • Synthetic collagen heterotrimers: structural mimics of wild-type and mutant collagen type I.  130:7509-7515. 2008
  • Sialoside analogue arrays for rapid identification of high affinity siglec ligands.  130:6680-6681. 2008
  • Total synthesis of biologically active natural products.  130:6654-6656. 2008
  • Carbon-deuterium bonds as probes of dihydrofolate reductase.  130:6597-6603. 2008
  • Characterization of the two-component, fad-dependent monooxygenase sgcc that requires carrier protein-tethered substrates for the biosynthesis of the enediyne antitumor antibiotic c-1027.  130:6616-6623. 2008
  • The role of tandem acyl carrier protein domains in polyunsaturated fatty acid biosynthesis.  130:6336-6337. 2008
  • Functional determinants of a synthetic vesicle fusion system.  130:6196-6205. 2008
  • A peptoid "antibody surrogate" that antagonizes VEGF receptor 2 activity.  130:5744-5752. 2008
  • Organocatalysis in a synthetic receptor with an inwardly directed carboxylic acid.  130:5658-5659. 2008
  • Analysis of the cryptophycin P450 epoxidase reveals substrate tolerance and cooperativity.  130:5492-5498. 2008
  • Fluorescent profiling of modular biosynthetic enzymes by complementary metabolic and activity based probes.  130:5443-5445. 2008
  • In situ generation of a bisubstrate analogue for protein arginine methyltransferase 1.  130:4574-4575. 2008
  • On-virus construction of polyvalent glycan ligands for cell-surface receptors.  130:4578-4579. 2008
  • Genetically encoding protein oxidative damage.  130:4028-4033. 2008
  • Total synthesis of the originally proposed and revised structures of palmerolide a and isomers thereof.  130:3633-3644. 2008
  • Minimally cationic cell-permeable miniature proteins via α-helical arginine display.  130:2948-2949. 2008
  • A templating approach for monodisperse self-assembled organic nanostructures.  130:2742-2743. 2008
  • Total synthesis of (+)-superstolide A.  130:2722-2723. 2008
  • Influence of remote asymmetric centers in reversible encapsulation complexes.  130:2450-2451. 2008
  • Discovery, characterization, and optimization of an unnatural base pair for expansion of the genetic alphabet.  130:2336-2343. 2008
  • Optimization of activity-based probes for proteomic profiling of histone deacetylase complexes.  130:2184-2194. 2008
  • Stability, dynamics, and selectivity in the assembly of hydrogen-bonded hexameric capsules.  130:2344-2350. 2008
  • Emergence of a single solid chiral state from a nearly racemic amino acid derivative.  130:1158-1159. 2008
  • Plasma clearance of bacteriophage Qβ particles as a function of surface charge.  130:1328-1334. 2008
  • A single-molecule nanopore device detects DNA polymerase activity with single-nucleotide resolution.  130:818-820. 2008
  • Catalysis of 3-pyrrolidinecarboxylic acid and related pyrrolidine derivatives in enantioselective anti-mannich-type reactions: Importance of the 3-acid group on pyrrolidine for stereocontrol.  130:875-886. 2008
  • Chemical synthesis of a glycoprotein having an intact human complex-type sialyloligosaccharide under the Boc and Fmoc synthetic strategies.  130:501-510. 2008
  • Direct coupling of catharanthine and vindoline to provide vinblastine: Total synthesis of (+)- and ent-(-)-vinblastine.  130:420-421. 2008
  • Selecting folded proteins from a library of secondary structural elements.  130:176-185. 2008
  • An expedient asymmetric synthesis of platencin.  130:11292-11293. 2008
  • Pd(II)-catalyzed cross-coupling of sp3 C-H Bonds with sp2 and sp3 boronic acids using air as the oxidant.  130:7190-7191. 2008
  • Ruthenium-catalyzed azide-alkyne cycloaddition: scope and mechanism.  130:8923-8930. 2008
  • Enrichment tags for enhanced-resolution profiling of the polar metabolome.  129:15780-15782. 2007
  • Methylrhenium trioxide revisited: mechanisms for nonredox oxygen insertion in an M-CH3 bond.  129:15794-15804. 2007
  • Structural and initial biological analysis of synthetic arylomycin A(2).  129:15830-15838. 2007
  • The mechanism of mio-based aminomutases in beta-amino acid biosynthesis.  129:15744-15745. 2007
  • Cavitands with introverted functionality stabilize tetrahedral intermediates.  129:15639-15643. 2007
  • A unique class of duocarmycin and CC-1065 analogues subject to reductive activation.  129:15391-15397. 2007
  • Clarification of the role of water in proline-mediated aldol reactions.  129:15100-15101. 2007
  • Contrasting two- and three-dimensional crystal properties of isomeric dialkyl phthalates.  129:15211-15217. 2007
  • Detection of reactive tetrahedral intermediates in a deep cavitand with an introverted functionality.  129:15330-15339. 2007
  • Synthesis of substituted 1,4-dienes by direct alkylation of allylic alcohols.  129:15112-15113. 2007
  • Fourier transform infrared characterization of a cu-b-nitrosyl complex in cytochrome ba3 from thermus thermophilus: Relevance to no reductase activity in heme-copper terminal oxidases.  129:14952-14958. 2007
  • Modular multi-level circuits from immobilized DNA-based logic gates.  129:14875-14879. 2007
  • Sila Morita-Baylis-Hillman reaction of cyclopropenes.  129:14868-14869. 2007
  • Site-specific insertion of 3-aminotyrosine into subunit α2 of E. coli ribonucleotide reductase: direct evidence for involvement of Y(730) and Y(731) in radical propagation.  129:15060-15071. 2007
  • Surprisingly high stability of collagen ABC heterotrimer: Evaluation of side chain charge pairs.  129:15034-15041. 2007
  • Synthesis of 5-fluoropyrimidine nucleotides as sensitive NMR probes of RNA structure.  129:14911-14921. 2007
  • Total synthesis and antibacterial properties of carbaplatensimycin.  129:14850-14851. 2007
  • Biophysical and structural characterization of a robust octameric β-peptide bundle.  129:14746-14751. 2007
  • D-fructose-6-phosphate aldolase-catalyzed one-pot synthesis of iminocyclitols.  129:14811-14817. 2007
  • Intrinsically cell-permeable miniature proteins based on a minimal cationic PPII motif.  129:14578-14579. 2007
  • Different apolipoproteins impact nanolipoprotein particle formation.  129:14348-14354. 2007
  • Rational design, synthesis, and evaluation of key analogues of CC-1065 and the duocarmycins.  129:14092-14099. 2007
  • Reengineering a natural riboswitch by dual genetic selection.  129:13814-13815. 2007
  • Tethering small molecules to a phage display library: discovery of a selective bivalent inhibitor of protein kinase A.  129:13812-13813. 2007
  • Extended sugar-assisted glycopeptide ligations: Development, scope, and applications.  129:13527-13536. 2007
  • Extraction of hydrophobic species into a water-soluble synthetic receptor.  129:13464-13473. 2007
  • Tailoring relaxation dispersion experiments for fast-associating protein complexes.  129:13406-13407. 2007
  • Characterization of the maduropeptin biosynthetic gene cluster from actinomadura madurae atcc 39144 supporting a unifying paradigm for enediyne biosynthesis.  129:13082-13094. 2007
  • Periodate-triggered cross-linking reveals Sug2/Rpt4 as the molecular target of a peptoid inhibitor of the 19S proteasome regulatory particle.  129:12936-12937. 2007
  • Anomeric reactivity-based one-pot synthesis of heparin-like oligosaccharides.  129:12795-12800. 2007
  • Benzimidazole and related ligands for Cu-catalyzed azide-alkyne cycloaddition.  129:12696-12704. 2007
  • Ligand-accelerated Cu-catalyzed azide-alkyne cycloaddition: a mechanistic report.  129:12705-12712. 2007
  • Scope and mechanism of direct indole and pyrrole couplings adjacent to carbonyl compounds: Total synthesis of acremoauxin A and oxazinin 3.  129:12857-12869. 2007
  • Design and synthesis of c5 methylated l-arginine analogues as active site probes for nitric oxide synthase.  129:12563-12570. 2007
  • Label transfer chemistry for the characterization of protein-protein interactions.  129:12348-12349. 2007
  • Regiospecific chlorination of (s)-ss-tyrosyl-s-carrier protein catalyzed by sgcc3 in the biosynthesis of the enediyne antitumor antibiotic c-1027.  129:12432-12438. 2007
  • Self-assembly of multidomain peptides: Balancing molecular frustration controls conformation and nanostructure.  129:12468-12472. 2007
  • The hydrophobic effect drives the recognition of hydrocarbons by an anionic metal-ligand cluster.  129:12094-12095. 2007
  • Synthesis of tamiflu and its phosphonate congeners possessing potent anti-influenza activity.  129:11892-11893. 2007
  • Quantitative analysis of carbohydrate-protein interactions using glycan microarrays: Determination of surface and solution dissociation constants.  129:11177-11184. 2007
  • Crystal structure of a biosynthetic sulfo-hirudin complexed to thrombin.  129:10648-10649. 2007
  • Prediction of the 3D structure and dynamics of human DP G-protein coupled receptor bound to an agonist and an antagonist.  129:10720-10731. 2007
  • Sequence-specific resonance assignment of soluble nonglobular proteins by 7D APSY-NMR Spectroscopy.  129:10823-10828. 2007
  • Systematic exploration of the structural features of yatakemycin impacting DNA alkylation and biological activity.  129:10858-10869. 2007
  • Efforts toward expansion of the genetic alphabet: structure and replication of unnatural base pairs.  129:10466-10473. 2007
  • Total synthesis of kinamycins C, F, and J.  129:10356-10357. 2007
  • Total synthesis, stereochemical reassignment, and absolute configuration of chlorofusin.  129:9860-9861. 2007
  • A functional proteomic strategy to discover inhibitors for uncharacterized hydrolases.  129:9594-9595. 2007
  • Guest recognition with micelle-bound cavitands.  129:9773-9779. 2007
  • A new mechanism for benzopyrone formation in aromatic polyketide biosynthesis.  129:9304-9305. 2007
  • Alanine scan of [L-Dap2]ramoplanin A2 aglycon:  Assessment of the importance of each residue.  129:8747-8755. 2007
  • In vivo site-specific DNA methylation with a designed sequence-enabled DNA methylase.  129:8676-8677. 2007
  • Self-assembly dynamics of a cylindrical capsule monitored by fluorescence resonance energy transfer.  129:8818-8824. 2007
  • Characterization of NcsB2 as a promiscuous naphthoic acid/coenzyme A ligase integral to the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin.  129:7728-7729. 2007
  • Identification of a peptoid inhibitor of the proteasome 19S regulatory particle.  129:7750-7751. 2007
  • Remarkable loop flexibility in avian influenza N1 and its implications for antiviral drug design.  129:7764-7765. 2007
  • Solution NMR studies of the maturation intermediates of a 13 MDa viral capsid.  129:7867-7876. 2007
  • Emergence of solution-phase homochirality via crystal engineering of amino acids.  129:7657-7660. 2007
  • Regio- and stereoselective cross-coupling of substituted olefins and imines. A convergent stereoselective synthesis of saturated 1,5-aminoalcohols and substituted piperidines.  129:7514-7516. 2007
  • Sugar-assisted ligation in glycoprotein synthesis.  129:7690-7701. 2007
  • Tailored glycoproteomics and glycan site mapping using saccharide-selective bioorthogonal probes.  129:7266-7267. 2007
  • Discrete heterogeneous quaternary structure formed by α/β-peptide foldamers and α-peptides.  129:6376-6377. 2007
  • Practical synthesis of enantiomerically pure β2)-amino acids via proline-catalyzed diastereoselective aminomethylation of aldehydes.  129:6050-6055. 2007
  • Biophysical characterization of a β-peptide bundle: Comparison to natural proteins.  129:5344-5345. 2007
  • Minor groove hydrogen bonds and the replication of unnatural base pairs.  129:5551-5557. 2007
  • Total synthesis of dimeric pyrrole-imidazole alkaloids: Sceptrin, ageliferin, nagelamide e, oxysceptrin, nakamuric acid, and the axinellamine carbon skeleton.  129:4762-4775. 2007
  • Helix bundle quaternary structure from α/β-peptide foldamers.  129:4178-4180. 2007
  • Assembly and exchange of resorcinarene capsules monitored by fluorescence resonance energy transfer.  129:3818-3819. 2007
  • Gold-catalyzed deoxygenated cyclization of cis-2,4-dien-1-als with regioselective addition of two nucleophiles. One-pot synthesis of highly functionalized cyclopentene framework.  129:3798-3799. 2007
  • Total syntheses of 2,2 '-epi-cytoskyrin a, rugulosin, and the alleged structure of rugulin.  129:4001-4013. 2007
  • Antibody-catalyzed oxidation of delta(9)-tetrahydrocannabinol.  129:3698-3702. 2007
  • Palladium-catalyzed methylation and arylation of sp2 and sp3 C-H bonds in simple carboxylic acids.  129:3510-3511. 2007
  • 8-Azaguanine reporter of purine ionization states in structured RNAs.  129:3426-3432. 2007
  • The case of the missing ring: Radical cleavage of a carbon-carbon bond and implications for gfp chromophore biosynthesis.  129:3118-3126. 2007
  • Functional and mechanistic analyses of biomimetic aminoacyl transfer reactions in de novo designed coiled coil peptides via rational active site engineering.  129:2959-2966. 2007
  • Design and synthesis of a BODIPY-alpha-tocopherol adduct for use as an off/on fluorescent antioxidant indicator.  129:1842-1843. 2007
  • High-resolution structure of a β-peptide bundle.  129:1532-1533. 2007
  • Quantitative evaluation of the relative cell permeability of peptoids and peptides.  129:1508-1509. 2007
  • Total synthesis of marinomycins A-C and of their monomeric counterparts monomarinomycin A and iso-monomarinomycin A.  129:1760-1768. 2007
  • Rhenium(vii) oxide catalyzed heteroacylative ring-opening dimerization of tetrahydrofuran.  129:1246-1253. 2007
  • Biomimetic catalysis of intermodular aminoacyl transfer.  129:748-749. 2007
  • Analysis of PUGNAc and NAG-thiazoline as transition state analogues for human O-GlcNAcase: mechanistic and structural insights into inhibitor selectivity and transition state poise.  129:635-644. 2007
  • Bifunctional catalysis of proton transfer at an antibody active site.  129:460-461. 2007
  • Design of a functional membrane protein by engineering a heme-binding site in glycophorin A.  129:512-518. 2007
  • Highly selective Diels-Alder reactions of directly connected enyne dienophiles.  129:645-657. 2007
  • Synthesis of potent bicyclic bisarylimidazole c-jun N-terminal kinase inhibitors by catalytic C-H bond activation.  129:490-491. 2007
  • Direct catalytic asymmetric synthesis of anti-1,2-amino alcohols and syn-1,2-diols through organocatalytic anti-mannich and syn-aldol reactions.  129:288-289. 2007
  • Total synthesis of abyssomicin c, atrop-abyssomicin c, and abyssomicin d: Implications for natural origins of atrop-abyssomicin c.  129:429-440. 2007
  • Reactivation of the p53 tumor suppressor pathway by a stapled p53 peptide.  129:2456-2457. 2007
  • Self-assembled heterotrimeric collagen triple helices directed through electrostatic interactions.  129:2683-2690. 2007
  • Synthetic seleno-glutaredoxin 3 analogues are highly reducing oxidoreductases with enhanced catalytic efficiency.  128:16684-16691. 2006
  • The two-state issue in the mixed-valence binuclear cu-a center in cytochrome c oxidase and n2o reductase.  128:16452-16453. 2006
  • Total synthesis and evaluation of cytostatin, its C10-C11 diastereomers, and additional key analogues: Impact on PP2A inhibition.  128:16720-16732. 2006
  • Amide-to-E-olefin versus amide-to-ester backbone H-bond perturbations: evaluating the O-O repulsion for extracting H-bond energies.  128:15948-15949. 2006
  • Total synthesis of amphidinolide E.  128:15960-15961. 2006
  • Asymmetric total synthesis of (+)- and ent-(-)-yatakemycin and duocarmycin SA: evaluation of yatakemycin key partial structures and its unnatural enantiomer.  128:15683-15696. 2006
  • Nucleophilic catalysis of hydrazone formation and transimination: implications for dynamic covalent chemistry.  128:15602-15603. 2006
  • A synthetic mimic of protein inner space: Buried polar interactions in a deep water-soluble host.  128:15366-15367. 2006
  • Unexpected acetylcholinesterase activity of cocaine esterases.  128:15364-15365. 2006
  • Chemistry of periodate-mediated cross-linking of 3,4-dihydroxylphenylalanine-containing molecules to proteins.  128:15228-15235. 2006
  • Coiled molecules in spring loaded devices.  128:15038-15039. 2006
  • Sugar-assisted ligation of N-linked glycopeptides with broad sequence tolerance at the ligation junction.  128:15026-15033. 2006
  • Activity-based protein profiling reagents for protein arginine deiminase 4 (pad4): Synthesis and in vitro evaluation of a fluorescently labeled probe.  128:14468-14469. 2006
  • Membrane activation: selective vesicle fusion via small molecule recognition.  128:14430-14431. 2006
  • Direct and high resolution characterization of cytochrome c equilibrium folding.  128:14232-14233. 2006
  • A genetically encoded infrared probe.  128:13984-13985. 2006
  • Delineation of a fundamental alpha-ketoheterocycle substituent effect for use in the design of enzyme inhibitors.  128:14004-14005. 2006
  • Total synthesis of (+/-)-chartelline C.  128:14028-14029. 2006
  • Circumventing the problems caused by protein diversity in microarrays: Implications for protein interaction networks.  128:13668-13669. 2006
  • Infrared line shape of an alpha-carbon deuterium-labeled amino acid.  128:13334-13335. 2006
  • Palladium-catalyzed alkylation of sp(2) and sp(3) c-h bonds with methylboroxine and alkylboronic acids: Two distinct c-h activation pathways.  128:12634-12635. 2006
  • Synthesis and evaluation of bioorthogonal pantetheine analogues for in vivo protein modification.  128:12174-12184. 2006
  • Total synthesis of piericidin A1 and B1 and key analogues.  128:11799-11807. 2006
  • Synthesis of taiwaniaquinoids via Nazarov triflation.  128:11022-11023. 2006
  • Cyclic peptide helices: A hybrid beta-hairpin/beta-helical supersecondary structure.  128:10650-10651. 2006
  • Physical controls on directed virus assembly at nanoscale chemical templates.  128:10801-10807. 2006
  • Rieske protein from thermus thermophilus: N-15 NMR titration study demonstrates the role of iron-ligated histidines in the ph dependence of the reduction potential.  128:10672-10673. 2006
  • Intramolecular Diels-Alder/1,3-dipolar cycloaddition cascade of 1,3,4-oxadiazoles.  128:10589-10595. 2006
  • The bifunctional glyceryl transferase/phosphatase ozmb belonging to the had superfamily that diverts 1,3-bisphosphoglycerate into polyketide biosynthesis.  128:10386-10387. 2006
  • Total synthesis of (-)- and ent-(+)-vindoline and related alkaloids.  128:10596-10612. 2006
  • A simple γ-backbone modification preorganizes peptide nucleic acid into a helical structure.  128:10258-10267. 2006
  • Sensitive and selective detection of nitric oxide using an h-nox domain.  128:10022-10023. 2006
  • 3-pyrrolidinecarboxylic acid for direct catalytic asymmetric anti-Mannich-type reactions of unmodified ketones.  128:9630-9631. 2006
  • The putative endocannabinoid transport blocker LY2183240 is a potent inhibitor of FAAH and several other brain serine hydrolases.  128:9699-9704. 2006
  • A reversible reaction inside a self-assembled capsule.  128:9308-9309. 2006
  • New RNA labeling methods offer dramatic sensitivity enhancements in 2H NMR relaxation spectra.  128:9346-9347. 2006
  • Facile functionalization of a metal carbon bond by O-atom transfer.  128:9018-9019. 2006
  • Structure-based discovery of glycolipids for CD1d-mediated NKT cell activation: Tuning the adjuvant versus immunosuppression activity.  128:9022-9023. 2006
  • A genetically encoded fluorescent amino acid.  128:8738-8739. 2006
  • Enantioselective total synthesis of avrainvillamide and the stephacidins.  128:8678-8693. 2006
  • Redox-coupled dynamics and folding in cytochrome c.  128:7909-7915. 2006
  • Carboxylic solvents and O-donor ligand effects on CH activation by Pt(II).  128:7404-7405. 2006
  • Mechanistic implications of pseudo zero order kinetics in kinetic resolutions.  128:7450-7451. 2006
  • Self-assembly of peptide-amphiphile nanofibers: The roles of hydrogen bonding and amphiphilic packing.  128:7291-7298. 2006
  • An efficiently extended class of unnatural base pairs.  128:6780-6781. 2006
  • Convergent, enantioselective syntheses of guanacastepenes A and E featuring a selective cyclobutane fragmentation.  128:7025-7035. 2006
  • Cu(ii)-catalyzed functionalizations of aryl c-h bonds using o-2 as an oxidant.  128:6790-6791. 2006
  • Synthesis of degradable model networks via atrp and click chemistry.  128:6564-6565. 2006
  • Optimization of unnatural base pair packing for polymerase recognition.  128:6369-6375. 2006
  • "Click" chemistry in a supramolecular environment: stabilization of organogels by copper(I)-catalyzed azide-alkyne [3 + 2] cycloaddition.  128:6056-6057. 2006
  • Efforts toward developing direct probes of protein dynamics.  128:6028-6029. 2006
  • Measurement of long-range 1H-19F scalar coupling constants and their glycosidic torsion dependence in 5-fluoropyrimidine-substituted RNA.  128:5851-5858. 2006
  • Non-uniformly sampled double-TROSY hNcaNH experiments for NMR sequential assignments of large proteins.  128:5757-5763. 2006
  • Sugar-assisted glycopeptide ligation.  128:5626-5627. 2006
  • Uncovering quantitative protein interaction networks for mouse PDZ domains using protein microarrays.  128:5913-5922. 2006
  • Expanded capsules with reversibly added spacers.  128:5314-5315. 2006
  • Molecular organization of cholesterol in unsaturated phosphatidylethanolamines: X-ray diffraction and solid state h-2 NMR reveal differences with phosphatidylcholines.  128:5375-5383. 2006
  • Direct nucleophilic acylation of nitroalkenes promoted by a fluoride anion/thiourea combination.  128:4932-4933. 2006
  • Fluorescent signal amplification of carbocyanine dyes using engineered viral nanoparticles.  128:5184-5189. 2006
  • Fluorescent sensors for organophosphorus nerve agent mimics.  128:4500-4501. 2006
  • The genetic incorporation of a distance probe into proteins in Escherichia coli.  128:4572-4573. 2006
  • Understanding GFP posttranslational chemistry: Structures of designed variants that achieve backbone fragmentation, hydrolysis, and decarboxylation.  128:4685-4693. 2006
  • Excited-state dynamics of structurally characterized [Re-I(CO)(3)(phen)(HisX)](+) (X=83,109) Pseudomonas aeruginosa azurins in aqueous solution.  128:4365-4370. 2006
  • Superactivation of the botulinum neurotoxin serotype A light chain metalloprotease: A new wrinkle in botulinum neurotoxin.  128:4176-4177. 2006
  • Total synthesis and biological evaluation of halipeptins a and d and analogues.  128:4460-4470. 2006
  • Cavitands with revolving doors regulate binding selectivities and rates in water.  128:3894-3895. 2006
  • Total synthesis of (+/-)-haouamine A.  128:3908-3909. 2006
  • An α-helical peptidomimetic inhibitor of the HIV-1 Rev-RRE interaction.  128:3496-3497. 2006
  • Reevaluation of the mechanism of the amination of aryl halides catalyzed by BINAP-ligated palladium complexes.  128:3584-3591. 2006
  • Structural evidence for an enolate intermediate in gfp fluorophore biosynthesis.  128:3166-3168. 2006
  • An alkoxide-directed carbometalation of internal alkynes.  128:2764-2765. 2006
  • Antibody interference with N-acyl homoserine lactone-mediated bacterial quorum sensing.  128:2802-2803. 2006
  • Total synthesis and evaluation of [Ψ[CH(2)NH]Tpg(4)]vancomycin aglycon: reengineering vancomycin for dual D-Ala-D-Ala and D-Ala-D-Lac binding.  128:2885-2892. 2006
  • Total synthesis and structural elucidation of azaspiracid-1. Final assignment and total synthesis of the correct structure of azaspiracid-1.  128:2859-2872. 2006
  • Diastereoselective Diels-Alder reactions of N-sulfonyl-1-aza-1,3-butadienes with optically active enol ethers: An asymmetric variant of the 1-azadiene Diels-Alder reaction.  128:2587-2593. 2006
  • Discovery of EGFR selective 4,6-disubstituted pyrimidines from a combinatorial kinase-directed heterocycle library.  128:2182-2183. 2006
  • Solvent isotope effects on interfacial protein electron transfer in crystals and electrode films.  128:2346-2355. 2006
  • Total synthesis and structural elucidation of azaspiracid-1. Construction of key building blocks for originally proposed structure.  128:2244-2257. 2006
  • Total synthesis and structural elucidation of azaspiracid-1. Synthesis-based analysis of originally proposed structures and indication of their non-identity to the natural product.  128:2258-2267. 2006
  • A fluoroacetamidine-based inactivator of protein arginine deiminase 4: Design, synthesis, and in vitro and in vivo evaluation.  128:1092-1093. 2006
  • Direct asymmetric anti-mannich-type reactions catalyzed by a designed amino acid.  128:1040-1041. 2006
  • Concise total syntheses of palominol, dolabellatrienone, beta-araneosene, and isoedunol via an enantioselective Diels-Alder macrobicyclization.  128:740-742. 2006
  • Enantioselective TADMAP-catalyzed carboxyl migration reactions for the synthesis of stereogenic quaternary carbon.  128:925-934. 2006
  • Organocatalytic direct asymmetric aldol reactions in water.  128:734-735. 2006
  • The incorporation of a photoisomerizable amino acid into proteins in E. coli.  128:388-389. 2006
  • Amino acid dependent formation of phosphate anhydrides in water mediated by carbonyl sulfide.  128:20-21. 2006
  • Palladium-catalyzed alkylation of aryl c-h bonds with sp(3) organotin reagents using benzoquinone as a crucial promoter.  128:78-79. 2006
  • Organocatalytic direct michael reaction of ketones and aldehydes with beta-nitrostyrene in brine.  128:4966-4967. 2006
  • Elucidation of fatty acid amide hydrolase inhibition by potent alpha-ketoheterocycle derivatives from Monte Carlo simulations.  127:17377-17384. 2005
  • Importance of tensor asymmetry for the analysis of (2)H NMR spectra from deuterated aromatic rings.  127:17488-17493. 2005
  • O-GlcNAcase catalyzes cleavage of thioglycosides without general acid catalysis.  127:17202-17203. 2005
  • Remarkable phosphine-effect on the intramolecular aldol reactions of unsaturated 1,5-diketones: highly regioselective synthesis of cross-conjugated dienones.  127:16778-16779. 2005
  • Cloning, sequencing, analysis, and heterologous expression of the fredericamycin biosynthetic gene cluster from streptomyces griseus.  127:16442-16452. 2005
  • Cysteine-derived organocatalyst in a highly enantioselective intramolecular Michael reaction.  127:16028-16029. 2005
  • Cysteine-derived organocatalyst in a highly enantioselective intramolecular michael reaction.  127:16028-16029. 2005
  • Ruthenium-catalyzed cycloaddition of alkynes and organic azides.  127:15998-15999. 2005
  • Active site structure of class I ribonucleotide reductase intermediate X: a density functional theory analysis of structure, energetics, and spectroscopy.  127:15778-15790. 2005
  • Total synthesis of piericidin A1 and B1.  127:15704-15705. 2005
  • Differential solvation and tautomer stability of a model base pair within the minor and major grooves of DNA.  127:15612-15617. 2005
  • E-olefin dipeptide isostere incorporation into a polypeptide backbone enables hydrogen bond perturbation: probing the requirements for Alzheimer's amyloidogenesis.  127:15366-15367. 2005
  • Enantioselective total syntheses of welwitindolinone A and fischerindoles I and G.  127:15394-15396. 2005
  • Discovery of a biologically active thiostrepton fragment.  127:15042-15044. 2005
  • Structural characterization of a p-acetylphenylalanyl aminoacyl-tRNA synthetase.  127:14976-14977. 2005
  • CH activation with an O-donor iridium-methoxo complex.  127:14172-14173. 2005
  • The allylic azide rearrangement: achieving selectivity.  127:13444-13445. 2005
  • Antibody-catalyzed asymmetric intramolecular michael addition of aldehydes and ketones to yield the disfavored cis-product.  127:13104-13105. 2005
  • Conformational substates modulate hydride transfer in dihydrofolate reductase.  127:12997-13006. 2005
  • Polymerase evolution: Efforts toward expansion of the genetic code.  127:12470-12471. 2005
  • Deep cavitands provide organized solvation of reactions.  127:11904-11905. 2005
  • Determination of the packing mode of the coiled-coil domain of cGMP-Dependent protein kinase I alpha in solution using charge-predicted dipolar couplings.  127:11918-11919. 2005
  • Iso-migrastatin congeners from streptomyces platensis and generation of a glutarimide polyketide library featuring the dorrigocin, lactimidomycin, migrastatin, and nk30424 scaffolds.  127:11930-11931. 2005
  • Biosynthesis of the beta-amino acid moiety of the enediyne antitumor antibiotic c-1027 featuring beta-amino acyl-s-carrier protein intermediates.  127:11594-11595. 2005
  • A deep cavitand provides a structured environment for the menschutkin reaction.  127:11222-11223. 2005
  • In vivo reporter labeling of proteins via metabolic delivery of coenzyme A analogues.  127:11234-11235. 2005
  • Redox couples of inducible nitric oxide synthase.  127:11212-11213. 2005
  • Synthesis, structure, and reactivity of O-donor Ir(III) complexes: C-H activation studies with benzene.  127:11372-11389. 2005
  • Total synthesis of asimicin via highly stereoselective [3 + 2] annulation reactions of substituted allylsilanes.  127:10818-10819. 2005
  • Total synthesis of thiostrepton. Assembly of key building blocks and completion of the synthesis.  127:11176-11183. 2005
  • Total synthesis of thiostrepton. Retrosynthetic analysis and construction of key building blocks.  127:11159-11175. 2005
  • Total synthesis of ningalin D.  127:10767-10770. 2005
  • Why are BINOL-based monophosphites such efficient ligands in Rh-catalyzed asymmetric olefin hydrogenation?.  127:10305-10313. 2005
  • A tandem orthogonal proteolysis strategy for high-content chemical proteomics.  127:10018-10019. 2005
  • Toward cocaine esterase therapeutics.  127:10016-10017. 2005
  • (4,2)D projection-reconstruction experiments for protein backbone assignment: application to human carbonic anhydrase II and calbindin D(28K).  127:8785-8795. 2005
  • The total synthesis of coleophomones B, C, and D.  127:8872-8888. 2005
  • A potent transactivation domain mimic with activity in living cells.  127:8254-8255. 2005
  • Controlling the morphology of cross beta-sheet assemblies by rational design.  127:8562-8570. 2005
  • Design, synthesis, and biological evaluation of HSP90 inhibitors based on conformational analysis of radicicol and its analogues.  127:6999-7004. 2005
  • In situ selection of lead compounds by click chemistry: Target-guided optimization of acetylcholinesterase inhibitors.  127:6686-6692. 2005
  • Potent and selective structure-based dibenzofuran inhibitors of transthyretin amyloidogenesis: Kinetic stabilization of the native state.  127:6662-6671. 2005
  • Biomimetic synthesis of antimalarial naphthoquinones.  127:6276-6283. 2005
  • Total synthesis of (+)-13-deoxytedanolide.  127:6186-6187. 2005
  • Tuning the enantioselective N-acetylation of racemic amines: A spectacular salt effect.  127:6138-6139. 2005
  • A designed synthetic analogue of 4-OT is specific for a non-natural substrate.  127:5862-5868. 2005
  • Experimental evidence for chair-like transition states in aldol reactions of methyl ketone lithium enolates: stereoselective synthesis and utilization of a deuterium-labeled enolate as a probe of reaction stereochemistry.  127:5770-5771. 2005
  • Kinetic stabilization of an oligomeric protein by a single ligand binding event.  127:5540-5551. 2005
  • Rhodopsin reconstituted into a planar-supported lipid bilayer retains photoactivity after cross-linking polymerization of lipid monomers.  127:5320-5321. 2005
  • Virus crystals as nanocomposite scaffolds.  127:5274-5275. 2005
  • Luminescent ruthenium(II)- and rhenium(I)-diimine wires bind nitric oxide synthase.  127:5169-5173. 2005
  • Tryptophan side chain electrostatic interactions determine edge-to-face vs parallel-displaced tryptophan side chain geometries in the designed β-hairpin "trpzip2".  127:4668-4674. 2005
  • The role of chelating diamine ligands in the goldberg reaction: a kinetic study on the copper-catalyzed amidation of aryl iodides.  127:4120-4121. 2005
  • A pentenyl dianion-based strategy for convergent synthesis of ene-1,5-diols.  127:3694-3695. 2005
  • Parallel biomolecular computation on surfaces with advanced finite automata.  127:3935-3943. 2005
  • Fluorescent cocaine probes: A tool for the selection and engineering of therapeutic antibodies.  127:2477-2484. 2005
  • Migrastatin and dorrigocins are shunt metabolites of iso-migrastatin.  127:1622-1623. 2005
  • Decomposition of triacetone triperoxide is an entropic explosion.  127:1146-1159. 2005
  • A dimerization "switch" in the internalization mechanism of a cell-penetrating peptide.  127:538-539. 2005
  • Copper(I)-catalyzed synthesis of azoles. DFT study predicts unprecedented reactivity and intermediates.  127:210-216. 2005
  • Origin of selectivity in the antibody 20f10-catalyzed yang cyclization.  127:132-145. 2005
  • Toward assessing the position-dependent contributions of backbone hydrogen bonding to β-sheet folding thermodynamics employing amide-to-ester perturbations.  126:16762-16771. 2004
  • A precipitator for the detection of thiophilic metals in aqua.  126:16582-16586. 2004
  • Catalysis by a synthetic receptor sealed at one end and functionalized at the other.  126:16280-16281. 2004
  • Porphyrin distortion during affinity maturation of a ferrochelatase antibody, monitored by resonance Raman spectroscopy.  126:16361-16367. 2004
  • Probing the active catalyst in product-accelerated proline-mediated reactions.  126:16312-16313. 2004
  • A phage display system with unnatural amino acids.  126:15962-15963. 2004
  • Microarray platform for profiling enzyme activities in complex proteomes.  126:15640-15641. 2004
  • Heterocyclic peptide backbone modifications in an α-helical coiled coil.  126:15366-15367. 2004
  • Development of a functionalized xenon biosensor.  126:15287-15294. 2004
  • Metal-assisted assembly and stabilization of collagen-like triple helices.  126:15030-15031. 2004
  • Enantioselective formal hydration of α,β-unsaturated imides by Al-catalyzed conjugate addition of oxime nucleophiles.  126:14724-14725. 2004
  • A genetically encoded photocaged amino acid.  126:14306-14307. 2004
  • Optimization of interstrand hydrophobic packing interactions within unnatural DNA base pairs.  126:14419-14427. 2004
  • Hydrogen-bonded encapsulation complexes in protic solvents.  126:14149-14156. 2004
  • Palladium-catalyzed synthesis of N-aryl-2-benzylindolines via tandem arylation of 2-allylaniline: control of selectivity through in situ catalyst modification.  126:13906-13907. 2004
  • Effects of lipid chain lengths in alpha-galactosylceramides on cytokine release by natural killer T cells.  126:13602-13603. 2004
  • Detection of bacteria with carbohydrate-functionalized fluorescent polymers.  126:13343-13346. 2004
  • Helical folding of alkanes in a self-assembled, cylindrical capsule.  126:13512-13518. 2004
  • Electrostatic interactions dominate the catalytic contribution of Arg39 in 4-oxalocrotonate tautomerase.  126:12726-12727. 2004
  • In situ click chemistry: Enzyme inhibitors made to their own specifications.  126:12809-12818. 2004
  • Mechanically regulated rotation of a guest in a nanoscale host.  126:12728-12729. 2004
  • On the role of the conserved aspartate in the hydrolysis of the phosphocysteine intermediate of the low molecular weight tyrosine phosphatase.  126:12677-12684. 2004
  • Enzymatic synthesis and 19F NMR studies of 2-fluoroadenine-substituted RNA.  126:11776-11777. 2004
  • In situ catalyst improvement in the proline-mediated alpha-amination of aldehydes.  126:11770-11771. 2004
  • Oligothiophene isocyanides for platinum-based molecular electronic applications.  126:11796-11797. 2004
  • The effect of mutation on RNA Diels-Alderases.  126:11843-11851. 2004
  • Equilibrium isotope effects as a probe of nonbonding attractions.  126:11428-11429. 2004
  • Immunological consequences of methamphetamine protein glycation.  126:11446-11447. 2004
  • Mechanistic analysis of hydroarylation catalysts.  126:11658-11665. 2004
  • Periodate-triggered cross-linking of dopa-containing peptide-protein complexes.  126:11442-11443. 2004
  • Boolean logic functions of a synthetic peptide network.  126:11140-11141. 2004
  • Electron transfer between cytochrome c and cytochome c peroxidase in single crystals.  126:10836-10837. 2004
  • Studies toward diazonamide A: Initial synthetic forays directed toward the originally proposed structure.  126:10162-10173. 2004
  • Selective derivatization and sequestration of ribose from a prebiotic mix.  126:9578-9583. 2004
  • A powerful selection assay for mixture libraries of DNA alkylating agents.  126:9194-9195. 2004
  • Discovery and characterization of catalysts for azide-alkyne cycloaddition by fluorescence quenching.  126:9152-9153. 2004
  • Total synthesis of formamicin.  126:9307-9317. 2004
  • Single molecule solvation and its effects on tautomeric equilibria in a self-assembled capsule.  126:8956-8960. 2004
  • Covalent display of oligosaccharide arrays in microtiter plates.  126:8640-8641. 2004
  • Evidence for a post-translational modification, aspartyl aldehyde, in a photosynthetic membrane protein.  126:8399-8405. 2004
  • Structural mining: self-consistent design on flexible protein-peptide docking and transferable binding affinity potential.  126:8515-8528. 2004
  • Total synthesis, structure revision, and absolute configuration of (+)-yatakemycin.  126:8396-8398. 2004
  • Nonspecific medium effects versus specific group positioning in the antibody and albumin catalysis of the base-promoted ring-opening reactions of benzisoxazoles.  126:8197-8205. 2004
  • Isotopomer encapsulation in a cylindrical molecular capsule: A probe for understanding noncovalent isotope effects on a molecular level.  126:7738-7739. 2004
  • NMR structure of a cyclic polyamide-DNA complex.  126:7958-7966. 2004
  • A functionalized, deep cavitand catalyzes the aminolysis of a choline derivative.  126:7424-7425. 2004
  • Direct coupling of indoles with carbonyl compounds: Short, enantioselective, gram-scale synthetic entry into the hapalindole and fischerindole alkaloid families.  126:7450-7451. 2004
  • Dissecting ramoplanin: mechanistic analysis of synthetic ramoplanin analogues as a guide to the design of improved antibiotics.  126:7462-7463. 2004
  • Precursor-directed biosynthesis of epothilone in Escherichia coli.  126:7436-7437. 2004
  • Efforts to expand the genetic alphabet: Identification of a replicable unnatural DNA self-pair.  126:6923-6931. 2004
  • A new method for the stereoselective synthesis of α- and β-glycosylamines using the burgess reagent.  126:6234-6235. 2004
  • Steric and magnetic asymmetry distinguished by encapsulation.  126:6216-6217. 2004
  • Designing sequence to control protein function in an EF-hand protein.  126:5990-5998. 2004
  • Antisymmetric exchange in 2fe-2s (1+) clusters: Epr of the rieske protein from thermus thermophilus at ph 14.  126:5338-5339. 2004
  • Biomimetically inspired total synthesis and structure activity relationships of 1-o-methyllateriflorone. 6 pi electrocyclizations in organic synthesis.  126:5493-5501. 2004
  • o-Iodoxybenzoic acid (IBX) as a viable reagent in the manipulation of nitrogen- and sulfur-containing substrates: scope, generality, and mechanism of IBX-mediated amine oxidations and dithiane deprotections.  126:5192-5201. 2004
  • Inhibition of the proteolytic activity of anthrax lethal factor by aminoglycosides.  126:4774-4775. 2004
  • Photolithographic synthesis of peptoids.  126:4088-4089. 2004
  • Total synthesis of the ristocetin aglycon.  126:4310-4317. 2004
  • Design and use of fluorogenic aldehydes for monitoring the progress of aldehyde transformations.  126:3692-3693. 2004
  • Short total synthesis of (+/-)-sceptrin.  126:3726-3727. 2004
  • A high-resolution probe of protein folding.  126:3384-3385. 2004
  • A catalysis-based selection for peroxidase antibodies with increased activity.  126:3006-3007. 2004
  • Kinetically stable complexes in water: The role of hydration and hydrophobicity.  126:2870-2876. 2004
  • Kinetics and thermodynamics of hexameric capsule formation.  126:2939-2943. 2004
  • Calculating the electron paramagnetic resonance parameters of exchange coupled transition metal complexes using broken symmetry density functional theory: application to a MnIII/MnIV model compound.  126:2613-2622. 2004
  • Cyclic amidine sugars as transition-state analogue inhibitors of glycosidases: Potent competitive inhibitors of mannosidases.  126:1971-1979. 2004
  • Expanding the substrate repertoire of a DNA polymerase by directed evolution.  126:1748-1754. 2004
  • Small molecules that induce cardiomyogenesis in embryonic stem cells.  126:1590-1591. 2004
  • Mapping enzyme active sites in complex proteomes.  126:1363-1368. 2004
  • Mechanistic investigation leads to a synthetic improvement in the hydrolytic kinetic resolution of terminal epoxides.  126:1360-1362. 2004
  • Total synthesis and examination of three key analogues of ramoplanin: a lipoglycodepsipeptide with potent antibiotic activity.  126:1041-1043. 2004
  • Dedifferentiation of lineage-committed cells by a small molecule.  126:410-411. 2004
  • Total synthesis of hamigerans and analogues thereof. Photochemical generation and diels-alder trapping of hydroxy-o-quinodimethanes.  126:613-627. 2004
  • Total synthesis of hybocarpone and analogues thereof. A facile dimerization of naphthazarins to pentacyclic systems.  126:607-612. 2004
  • Establishing the parabolic relationship between reactivity and activity for derivatives and analogues of the duocarmycin and CC-1065 alkylation subunits.  126:80-81. 2004
  • Mechanism of homogeneous Ir(III) catalyzed regioselective arylation of olefins.  126:352-363. 2004
  • Chemistry and biology of diazonamide A: First total synthesis and confirmation of the true structure.  126:12888-12896. 2004
  • Chemistry and biology of diazonamide A: Second total synthesis and biological investigations.  126:12897-12906. 2004
  • Studies toward diazonamide A: Development of a hetero-pinacol macrocyclization cascade for the construction of the bis-macrocyclic framework of the originally proposed structure.  126:10174-10182. 2004
  • Application of NMR SHAPES screening to an RNA target.  125:15724-15725. 2003
  • Fundamental role of the fostriecin unsaturated lactone and implications for selective protein phosphatase inhibition.  125:15694-15695. 2003
  • Catalysis of the photo-Fries reaction: Antibody-mediated stabilization of high energy states.  125:15395-15401. 2003
  • Total synthesis of apoptolidin: Completion of the synthesis and analogue synthesis and evaluation.  125:15443-15454. 2003
  • Total synthesis of apoptolidin: Construction of enantiomerically pure fragments.  125:15433-15442. 2003
  • Mechanism of the glutathione transferase-catalyzed conversion of antitumor 2-crotonyloxymethyl-2-cycloalkenones to GSH adducts.  125:15049-15058. 2003
  • Reactivity and molecular recognition: Amine methylation by an introverted ester.  125:14682-14683. 2003
  • Reversible switching of high-speed air-liquid two-phase flows using electrowetting-assisted flow-pattern change.  125:14678-14679. 2003
  • Site-specific incorporation of a redox-active amino acid into proteins.  125:14662-14663. 2003
  • Alkane C-H activation and catalysis by an O-donor ligated iridium complex.  125:14292-14293. 2003
  • Spectroscopy and reactivity of a photogenerated tryptophan radical in a structurally defined protein environment.  125:14220-14221. 2003
  • Individual solvent/solute interactions through social isomerism.  125:13981-13983. 2003
  • Insights into the origin of high activity and stability of catalysts derived from bulky, electron-rich monophosphinobiaryl ligands in the Pd-catalyzed C-N bond formation.  125:13978-13980. 2003
  • Isolation of protein ligands from large peptoid libraries.  125:13995-14004. 2003
  • Synthesis and characterization of potent bivalent amyloidosis inhibitors that bind prior to transthyretin tetramerization.  125:13404-13414. 2003
  • Structure of antibacterial peptide microcin J25: a 21-residue lariat protoknot.  125:12382-12383. 2003
  • Understanding the mechanism of H(+)-induced demetalation as a design strategy for robust iron(III) peroxide-activating catalysts.  125:12378-12379. 2003
  • A selective irreversible inhibitor targeting a PDZ protein interaction domain.  125:12074-12075. 2003
  • Combined experimental/theoretical refinement of indole ring geometry using deuterium magnetic resonance and ab initio calculations.  125:12268-12276. 2003
  • Adding amino acids with novel reactivity to the genetic code of Saccharomyces cerevisiae.  125:11782-11783. 2003
  • DNA alkylation properties of yatakemycin.  125:10971-10976. 2003
  • Why is tetrazole formation by addition of azide to organic nitriles catalyzed by zinc(II) salts?.  125:9983-9987. 2003
  • A potent and highly selective inhibitor of human α-1,3-fucosyltransferase via click chemistry.  125:9588-9589. 2003
  • Determinants of unnatural nucleobase stability and polymerase recognition.  125:9638-9646. 2003
  • Mixed-element capture agents: A simple strategy for the construction of synthetic, high-affinity protein capture ligands.  125:9550-9551. 2003
  • Theoretical examination of Mg(2+)-mediated hydrolysis of a phosphodiester linkage as proposed for the hammerhead ribozyme.  125:9861-9867. 2003
  • A heterocyclic peptide nanotube.  125:9372-9376. 2003
  • Partitioning the loss in vancomycin binding affinity for D-Ala-D-Lac into lost H-bond and repulsive lone pair contributions.  125:9314-9315. 2003
  • Kinetic evidence for a tetrameric transition state in the asymmetric autocatalytic alkylation of pyrimidyl aldehydes.  125:8978-8979. 2003
  • Fluorescent detection of carbon-carbon bond formation.  125:8523-8528. 2003
  • Photoisomerization and proton transfer in photoactive yellow protein.  125:8186-8194. 2003
  • Structural, spectroscopic, and redox consequences of central ligand in the FeMoco of nitrogenase: a density functional theoretical study.  125:8377-8383. 2003
  • A bifunctional molecule that displays context-dependent cellular activity.  125:7575-7580. 2003
  • A new strategy for improved nicotine vaccines using conformationally constrained haptens.  125:7164-7165. 2003
  • Self-assembly combining two bioactive peptide-amphiphile molecules into nanofibers by electrostatic attraction.  125:7146-7147. 2003
  • Fabrication of assembled virus nanostructures on templates of chemoselective linkers formed by scanning probe nanolithography.  125:6848-6849. 2003
  • Novel selective inhibitors of the interaction of individual nuclear hormone receptors with a mutually shared steroid receptor coactivator 2.  125:6852-6853. 2003
  • Symmetry and bonding in metalloporphyrins. A modern implementation for the bonding analyses of five- and six-coordinate high-spin iron(III)-porphyrin complexes through density functional calculation and NMR spectroscopy.  125:6774-6783. 2003
  • A novel 4-methylideneimidazole-5-one-containing tyrosine aminomutase in enediyne antitumor antibiotic c-1027 biosynthesis.  125:6062-6063. 2003
  • Asymmetric environments in encapsulation complexes.  125:6239-6243. 2003
  • The effect of minor-groove hydrogen-bond acceptors and donors on the stability and replication of four unnatural base pairs.  125:6134-6139. 2003
  • Short, enantioselective total synthesis of okaramine n.  125:5628-5629. 2003
  • Theoretical calculations of carbon-oxygen bond dissociation enthalpies of peroxyl radicals formed in the autoxidation of lipids.  125:5801-5810. 2003
  • An enantioselective synthesis of FR182877 provides a chemical rationalization of its structure and affords multigram quantities of its direct precursor.  125:5393-5407. 2003
  • Activity-based protein profiling in vivo using a copper(i)-catalyzed azide-alkyne 3+2 cycloaddition.  125:4686-4687. 2003
  • Hybridization-based unquenching of DNA hairpins on au surfaces: prototypical "molecular beacon" biosensors.  125:4012-4013. 2003
  • Adsorption of beta-hairpin peptides on the surface of water: A neutron reflection study.  125:3751-3757. 2003
  • Assembly of resorcinarene capsules in wet solvents.  125:3432-3433. 2003
  • Epothilone C macrolactonization and hydrolysis are catalyzed by the isolated thioesterase domain of epothilone polyketide synthase.  125:3428-3429. 2003
  • A mild, catalytic, and highly selective method for the oxidation of alpha,beta-enones to 1,4-enediones.  125:3232-3233. 2003
  • Bioconjugation by copper(I)-catalyzed azide-alkyne [3 + 2] cycloaddition.  125:3192-3193. 2003
  • A copper-catalyzed C-N bond formation involving sp-hybridized carbons. A direct entry to chiral ynamides via N-alkynylation of amides.  125:2368-2369. 2003
  • Experimental determination of the absolute enantioselectivity of an anti body-catalyzed Diels-Alder reaction and theoretical explorations of the origins of stereoselectivity.  125:2489-2506. 2003
  • Synthesis and activity of ruthenium alkylidene complexes coordinated with phosphine and N-heterocyclic carbene ligands.  125:2546-2558. 2003
  • A method for the generation of glycoprotein mimetics.  125:1702-1703. 2003
  • Density functional and reduction potential calculations of Fe4S4 clusters.  125:1923-1936. 2003
  • Total synthesis of the ramoplanin a2 and ramoplanose aglycon.  125:1877-1887. 2003
  • Generation of a bacterium with a 21 amino acid genetic code.  125:935-939. 2003
  • Small-molecule switches for zinc finger transcription factors.  125:612-613. 2003
  • DNA detection and signal amplification via an engineered allosteric enzyme.  125:344-345. 2003
  • DNA-based photonic logic gates: AND, NAND, and INHIBIT.  125:346-347. 2003
  • A potent and highly selective sulfotransferase inhibitor.  124:14524-14525. 2002
  • A small molecule with osteogenesis-inducing activity in multipotent mesenchymal progenitor cells.  124:14520-14521. 2002
  • Enzymatic phosphorylation of unnatural nucleosides.  124:14626-14630. 2002
  • Synthesis of sugar arrays in microtiter plate.  124:14397-14402. 2002
  • A synthetic receptor for choline and carnitine.  124:14014-14016. 2002
  • Mechanistic insights into the Pd(BINAP)-catalyzed amination of aryl bromides: kinetic studies under synthetically relevant conditions.  124:14104-14114. 2002
  • A novel silver(I)-mediated DNA base pair.  124:13684-13685. 2002
  • Crystal structure of a B-form DNA duplex containing (L)-alpha-threofuranosyl (3 '-> 2 ') nucleosides: A four-carbon sugar is easily accommodated into the backbone of DNA.  124:13716-13721. 2002
  • Enantioselective synthesis of 1,5-anti- and 1,5-syn-diols using a highly diastereoselective one-pot double allylboration reaction sequence.  124:13644-13645. 2002
  • Rationalization of anomalous nonlinear effects in the alkylation of substituted benzaldehydes.  124:13652-13653. 2002
  • Membraneless vanadium redox fuel cell using laminar flow.  124:12930-12931. 2002
  • Phage-display selection of a human single-chain fv antibody highly specific for melanoma and breast cancer cells using a chemoenzymatically synthesized G(M3)-carbohydrate antigen.  124:12439-12446. 2002
  • RNA-cleaving DNA enzymes with altered regio- or enantioselectivity.  124:12499-12506. 2002
  • Mechanisms of tetrazole formation by addition of azide to nitriles.  124:12210-12216. 2002
  • Social isomers in encapsulation complexes.  124:12074-12075. 2002
  • Solution NMR techniques for large molecular and supramolecular structures.  124:12144-12153. 2002
  • Synthesis of a negatively charged dibenzofuran-based beta-turn mimetic and its incorporation into the WW miniprotein-enhanced solubility without a loss of thermodynamic stability.  124:11900-11907. 2002
  • Intramolecular Diels-Alder and tandem intramolecular Diels-Alder/1,3-dipolar cycloaddition reactions of 1,3,4-oxadiazoles.  124:11292-11294. 2002
  • Synthesis and DNA binding properties of iminodiacetic acid-linked polyamides: characterization of cooperative extended 2 : 1 side-by-side parallel binding.  124:10676-10682. 2002
  • The chemistry of amine-azide interconversion: Catalytic diazotransfer and regioselective azide reduction.  124:10773-10778. 2002
  • The origin of diastereofacial control in allylboration reactions using tartrate ester derived allylboronates: attractive interactions between the Lewis acid coordinated aldehyde carbonyl group and an ester carbonyl oxygen.  124:10692-10697. 2002
  • Atropselective macrocyclization of diaryl ether ring systems: Application to the synthesis of vancomycin model systems.  124:10451-10455. 2002
  • Callipeltoside A: total synthesis, assignment of the absolute and relative configuration, and evaluation of synthetic analogues.  124:10396-10415. 2002
  • Fluorescent probes for cytochrome p450 structural characterization and inhibitor screening.  124:10254-10255. 2002
  • Metal-switching and self-inclusion of functional cavitands.  124:10349-10358. 2002
  • Density functional study of the mechanism of a tyrosine phosphatase: I. Intermediate formation.  124:10225-10235. 2002
  • Modulating ion channel properties of transmembrane peptide nanotubes through heteromeric supramolecular assemblies.  124:10004-10005. 2002
  • Contribution of aromatic interactions to alpha-helix stability.  124:9751-9755. 2002
  • Addition of p-azido-L-phenylaianine to the genetic code of Escherichia coli.  124:9026-9027. 2002
  • Cell-wall engineering of living bacteria.  124:9018-9019. 2002
  • An NMR study of the rates of single-molecule exchange in a cylindrical host capsule.  124:8780-8781. 2002
  • A short synthetic route to (+)-austamide, (+)-deoxyisoaustamide, and (+)-hydratoaustamide from a common precursor by a novel palladium-mediated indole -> dihydroindoloazocine cyclization.  124:7904-7905. 2002
  • Total synthesis of (-)-bafilomycin A(1).  124:6981-6990. 2002
  • Tpptme(h)(2): Why is there h/d scrambling of the methyl group but not methane loss?.  124:7041-7054. 2002
  • A structural model for the high-valent intermediate Q of methane monooxygenase from broken-symmetry density functional and electrostatics calculations.  124:5890-5894. 2002
  • Efficient chemoenzymatic synthesis of o-linked sialyl oligosaccharides.  124:5739-5746. 2002
  • Novel chemistry of alpha-tosyloxy ketones: Applications to the solution- and solid-phase synthesis of privileged heterocycle and enediyne libraries.  124:5718-5728. 2002
  • Solution-phase parallel synthesis of a pharmacophore library of hun-7293 analogues: a general chemical mutagenesis approach to defining structure-function properties of naturally occurring cyclic (depsi)peptides.  124:5431-5440. 2002
  • Template-directed self-assembly of 10-mu m-sized hexagonal plates.  124:5419-5426. 2002
  • Total synthesis of the ramoplanin a2 and ramoplanose aglycon.  124:5288-5290. 2002
  • A parallel approach to the discovery of carrier delivery vehicles to enhance antigen immunogenicity.  124:4946-4947. 2002
  • The effect of backbone cyclization on the thermodynamics of beta-sheet unfolding: Stability optimization of the PINWW domain.  124:4980-4986. 2002
  • A synthesis of (+)-FR182877, featuring tandem transannular Diels-Alder reactions inspired by a postulated biogenesis.  124:4552-4553. 2002
  • Binding modes for the first coupled electron and proton addition to FeMoco of nitrogenase.  124:4546-4547. 2002
  • Extending synthetic access to proteins with a removable acyl transfer auxiliary.  124:4642-4646. 2002
  • A modular assembly strategy for improving the substrate specificity of small catalytic peptides.  124:3510-3511. 2002
  • Magnetic resonance imaging detects a specific peptide-protein binding event.  124:3514-3515. 2002
  • Ruthenium-mediated cycloaromatization of acyclic enediynes and dienynes at ambient temperature.  124:3506-3507. 2002
  • Solid-phase synthesis of oligosaccharides and on-resin quantitative monitoring using gated decoupling c-13 NMR.  124:3591-3599. 2002
  • Structural chemistry of a green fluorescent protein zn biosensor.  124:3522-3524. 2002
  • Synthesis, properties, and reactivity of cocaine benzoylthio ester possessing the cocaine absolute configuration.  124:3661-3668. 2002
  • Aqueous aldol catalysis by a nicotine metabolite.  124:3220-3221. 2002
  • Water-stabilized cavitands.  124:2854-2855. 2002
  • The vinylogous intramolecular Morita-Baylis-Hillman reaction: synthesis of functionalized cyclopentenes and cyclohexenes with trialkylphosphines as nucleophilic catalysts.  124:2404-2405. 2002
  • Hairpin versus extended DNA binding of a substituted beta-alanine linked polyamide.  124:2148-2152. 2002
  • Iodine(V) reagents in organic synthesis. Part 1. Synthesis of polycyclic heterocycles via Dess-Martin periodinane-mediated cascade cyclization: Generality, scope, and mechanism of the reaction.  124:2212-2220. 2002
  • Iodine(V) reagents in organic synthesis. Part 2. Access to complex molecular architectures via Dess-Martin periodinane-generated o-imidoquinones.  124:2221-2232. 2002
  • Iodine(V) reagents in organic synthesis. Part 3. New routes to heterocyclic compounds via o-iodoxybenzoic acid-mediated cyclizations: Generality, scope, and mechanism.  124:2233-2244. 2002
  • Iodine(V) reagents in organic synthesis. Part 4. O-iodoxybenzoic acid as a chemospecific tool for single electron transfer-based oxidation processes.  124:2245-2258. 2002
  • Total synthesis of the CP-molecules (CP-263,114 and CP-225,917, phomoidrides B and A). 1. Racemic and asymmetric synthesis of bicyclo 4.3.1 key building blocks.  124:2183-2189. 2002
  • Total synthesis of the CP-molecules (CP-263,114 and CP-225,917, phomoidrides B and A). 2. Model studies for the construction of key structural elements and first-generation strategy.  124:2190-2201. 2002
  • Total synthesis of the CP-molecules (CP-263,114 and CP-225,917, phomoidrides B and A). 3. Completion and synthesis of advanced analogues.  124:2202-2211. 2002
  • A highly enantioselective amino acid-catalyzed route to functionalized alpha-amino acids.  124:1842-1843. 2002
  • A highly enantioselective route to either enantiomer of both alpha- and beta-amino acid derivatives.  124:1866-1867. 2002
  • Adding L-3-(2-naphthyl)alanine to the genetic code of E. coli.  124:1836-1837. 2002
  • Protein dynamics and cytochrome c: Correlations between ligand vibrations and redox activity.  124:1846-1847. 2002
  • The synthesis and biological characterization of a ceramide library.  124:1856-1857. 2002
  • Toward synthetic transcription activators: Recruitment of transcription factors to DNA by a pna-peptide chimera.  124:1838-1839. 2002
  • A combinatorial scaffold approach toward kinase-directed heterocycle libraries.  124:1594-1596. 2002
  • Stability and selectivity of unnatural DNA with five-membered-ring nucleobase analogues.  124:1222-1226. 2002
  • Erythropoietin mimetics derived from solution phase combinatorial libraries.  124:544-555. 2002
  • Design of three-dimensional, millimeter-scale models for molecular folding.  124:18-19. 2002
  • An enzyme library approach to biocatalysis: development of nitrilases for enantioselective production of carboxylic acid derivatives.  124:9024-9025. 2002
  • Tppt(iv)me(h)(2) forms a sigma-ch4 complex that is kinetically resistant to methane liberation.  124:3226-3228. 2002
  • FeMo cofactor of nitrogenase: a density functional study of states M(N), M(OX), M(R), and M(I).  123:12392-12410. 2001
  • Structure of a copper-mediated base pair in DNA.  123:12364-12367. 2001
  • "Flexiball" toolkit: A modular approach to self-assembling capsules.  123:11519-11533. 2001
  • Design of allele-specific protein methyltransferase inhibitors.  123:11608-11613. 2001
  • Electron tunneling in single crystals of Pseudomonas aeruginosa azurins.  123:11623-11631. 2001
  • Substrate recognition and selection by the initiation module PheATE of gramicidin S synthetase.  123:11208-11218. 2001
  • Concise asymmetric syntheses of radicicol and monocillin I.  123:10903-10908. 2001
  • Microbial glycosyltransferases for carbohydrate synthesis: Alpha-2,3-sialyltransferase from neisseria gonorrheae.  123:10909-10918. 2001
  • A self-folding metallocavitand.  123:9929-9934. 2001
  • Origins of asymmetric amplification in autocatalytic alkylzinc additions.  123:10103-10104. 2001
  • An efficient chemoenzymatic strategy for the synthesis of wild-type and vancomycin-resistant bacterial cell-wall precursors: UDP-N-acetylmuramyl-peptides.  123:9916-9917. 2001
  • Complete thermodynamic characterization of reduction and protonation of the bc(1)-type rieske 2fe-2s center of thermus thermophilus.  123:9906-9907. 2001
  • Chemical synthesis and biological evaluation of cis- and trans-12,13-cyclopropyl and 12,13-cyclobutyl epothilones and related pyridine side chain analogues.  123:9313-9323. 2001
  • Metal cation complexation and activation of reversed CPyi analogues of CC-1065 and duocarmycin SA: Partitioning the effects of binding and catalysis.  123:9299-9306. 2001
  • Total synthesis of deschlorocallipeltoside A.  123:9449-9450. 2001
  • Asymmetric total synthesis of ent-(-)-roseophilin: Assignment of absolute configuration.  123:8515-8519. 2001
  • Synthesis and catalytic antibody functionalization of dendrimers.  123:8248-8259. 2001
  • Three-dimensional self-assembly of complex, millimeter-scale structures through capillary bonding.  123:8119-8120. 2001
  • Self-assembly of 10-mu m-sized objects into ordered three-dimensional arrays.  123:7677-7682. 2001
  • Efforts toward expansion of the genetic alphabet: replication of DNA with three base pairs.  123:7439-7440. 2001
  • A simple, high-resolution method for establishing DNA binding affinity and sequence selectivity.  123:5878-5891. 2001
  • Amino acid catalyzed direct asymmetric aldol reactions: A bioorganic approach to catalytic asymmetric carbon-carbon bond-forming reactions.  123:5260-5267. 2001
  • Chiral softballs: Synthesis and molecular recognition properties.  123:5213-5220. 2001
  • Incorporating beta-turns and a turn mimetic out of context in loop 1 of the WW domain affords cooperatively folded beta-sheets.  123:5206-5212. 2001
  • Cavitand-porphyrins.  123:4659-4669. 2001
  • Observation of unusual kinetics in Heck reactions of aryl halides: the role of non-steady-state catalyst concentration.  123:4621-4622. 2001
  • Tautomerization dynamics of a model base pair in DNA.  123:4613-4614. 2001
  • Monitoring the conformational fluctuations of DNA hairpins using single-pair fluorescence resonance energy transfer.  123:4295-4303. 2001
  • Total synthesis of fostriecin (CI-920).  123:4161-4167. 2001
  • Conversion of enediynes into quinones by antibody catalysis and in aqueous buffers: Implications for an alternative enediynes therapeutic mechanism.  123:3607-3608. 2001
  • Cloning and heterologous expression of the macrotetrolide biosynthetic gene cluster revealed a novel polyketide synthase that lacks an acyl carrier protein.  123:3385-3386. 2001
  • Modulating artificial membrane morphology: Ph-induced chromatic transition and nanostructural transformation of a bolaamphiphilic conjugated polymer from blue helical ribbons to red nanofibers.  123:3205-3213. 2001
  • Residual dipolar coupling TOCSY for direct through space correlations of base protons and phosphorus nuclei in RNA.  123:3395-3396. 2001
  • Properties of photogenerated tryptophan and tyrosyl radicals in structurally characterized proteins containing rhenium(I) tricarbonyl diimines.  123:3181-3182. 2001
  • Selective oxidation at carbon adjacent to aromatic systems with IBX.  123:3183-3185. 2001
  • Sequence-dependent correction of random coil NMR chemical shifts.  123:2970-2978. 2001
  • Direct observation of protein vibrations by selective incorporation of spectroscopically observable carbon-deuterium bonds in cytochrome c.  123:2426-2427. 2001
  • A de novo designed peptide ligase: A mechanistic investigation.  123:1797-1803. 2001
  • First and second generation total synthesis of the teicoplanin aglycon.  123:1862-1871. 2001
  • Kinetic studies of heck coupling reactions using palladacycle catalysts: Experimental and kinetic modeling of the role of dimer species.  123:1848-1855. 2001
  • High-temperature protein mass mapping using a thermophilic protease.  123:1774-1775. 2001
  • An inhibitor of the interaction of thyroid hormone receptor beta and glucocorticoid interacting protein 1.  123:1525-1526. 2001
  • Identification of a novel class of small-molecule antiangiogenic agents through the screening of combinatorial libraries which function by inhibiting the binding and localization of proteinase MMP2 to integrin alpha(V)beta(3).  123:1280-1288. 2001
  • C-13,c-13 - and c-13,h-1 -trosy in a triple resonance experiment for ribose-base and intrabase correlations in nucleic acids.  123:658-664. 2001
  • Chromatographic purification of soluble single-walled carbon nanotubes (s-SWNTs).  123:733-734. 2001
  • Kinetic resolution using enantioimpure catalysts: mechanistic considerations of complex rate laws.  123:545-553. 2001
  • Medium-dependent self-assembly of an amphiphilic peptide: Direct observation of peptide phase domains at the air-water interface.  123:775-776. 2001
  • Synthesis of peptides and proteins without cysteine residues by native chemical ligation combined with desulfurization.  123:526-533. 2001
  • Total syntheses of thiocoraline and be-22179 and assessment of their DNA binding and biological properties.  123:561-568. 2001
  • Conformational analysis of a flexible oligosaccharide using residual dipolar couplings.  123:485-492. 2001
  • Design, synthesis, and characterization of 4-ester CI2, a model for backbone hydrogen bonding in protein α-helices.  122:12079-12082. 2000
  • Total synthesis of the rubrolone aglycon.  122:12169-12173. 2000
  • Cyclic peptides as molecular adapters for a pore-forming protein.  122:11757-11766. 2000
  • Structural basis for BABIM inhibition of botulinum neurotoxin type B protease.  122:11268-11269. 2000
  • Chemically reactive immunogens lead to functional convergence of the immune response.  122:10743-10753. 2000
  • Emergent conformational preferences of a self-assembling small molecule: Structure and dynamics in a tetrameric capsule.  122:10991-10996. 2000
  • A novel copper-mediated DNA base pair.  122:10714-10715. 2000
  • Titanium and zirconium et2c2b4h4-metal-phosphine complexes: Synthesis, characterization, and ethylene polymerization activity.  122:10573-10580. 2000
  • A phototautomerizable model DNA base pair.  122:9917-9920. 2000
  • Natural product-like combinatorial libraries based on privileged structures. 1. General principles and solid-phase synthesis of benzopyrans.  122:9939-9953. 2000
  • Natural product-like combinatorial libraries based on privileged structures. 2. Construction of a 10 000-membered benzopyran library by directed split-and-pool chemistry using nanokans and optical encoding.  122:9954-9967. 2000
  • Natural product-like combinatorial libraries based on privileged structures. 3. The "libraries from libraries" principle for diversity enhancement of benzopyran libraries.  122:9968-9976. 2000
  • Novel solution- and solid-phase chemistry of α-sulfonated ketones applicable to combinatorial chemistry.  122:10246-10248. 2000
  • Thermal atropisomerism of teicoplanin aglycon derivatives: Preparation of the P,P,P and M,P,P atropisomers of the teicoplanin aglycon via selective equilibration of the DE ring system.  122:10047-10055. 2000
  • Expanded calix[4]arene tetraurea capsules.  122:9868-9869. 2000
  • New molecular vessels: Synthesis and chiroselective recognition.  122:9628-9630. 2000
  • A concise synthesis of (-)-hispidospermidin guided by a postulated biogenesis.  122:9556-9557. 2000
  • Self-folding cavitands of nanoscale dimensions.  122:8880-8889. 2000
  • Rational design of an unnatural base pair with increased kinetic selectivity.  122:8803-8804. 2000
  • Surveying for surfaces that resist the adsorption of proteins.  122:8303-8304. 2000
  • Detection and mechanistic studies of multicomponent assembly by fluorescence resonance energy transfer.  122:7876-7882. 2000
  • Chiral space in a unimolecular capsule.  122:7811-7812. 2000
  • Efforts toward expansion of the genetic alphabet: optimization of interbase hydrophobic interactions.  122:7621-7632. 2000
  • A new method for the one-step synthesis of alpha,beta-unsaturated carbonyl systems from saturated alcohols and carbonyl compounds.  122:7596-7597. 2000
  • Highly enantioselective palladium(ii)-catalyzed cyclization of (z)-4 '-acetoxy-2 '-butenyl 2-alkynoates: An efficient synthesis of optically active gamma-butyrolactones.  122:7604-7605. 2000
  • Nmr assignment and secondary structure determination of an octameric 110 kda protein using trosy in triple resonance experiments.  122:7543-7548. 2000
  • Anti-markovnikov olefin arylation catalyzed by an iridium complex.  122:7414-7415. 2000
  • Total synthesis of the teicoplanin aglycon.  122:7416-7417. 2000
  • Polymer-supported (Salen)Mn catalysts for asymmetric epoxidation: A comparison between soluble and insoluble matrices.  122:6929-6934. 2000
  • Total synthesis of distamycin A and 2640 analogues: A solution-phase combinatorial approach to the discovery of new, bioactive DNA binding agents and development of a rapid, high-throughput screen for determining relative DNA binding affinity or DNA binding sequence selectivity.  122:6382-6394. 2000
  • A new method of in situ activation for a novel class of DNA alkylating agents: tunable metal cation complexation and activation.  122:6325-6326. 2000
  • A highly stereoselective synthesis of the landomycin A hexasaccharide unit.  122:6124-6125. 2000
  • Intein-mediated synthesis of proteins containing carbohydrates and other molecular probes.  122:5421-5428. 2000
  • Protofilaments, filaments, ribbons, and fibrils from peptidomimetic self-assembly: Implications for amyloid fibril formation and materials science.  122:5262-5277. 2000
  • Design of bifunctional antibiotics that target bacterial rRNA and inhibit resistance-causing enzymes.  122:5230-5231. 2000
  • A new functional suppressor tRNA/aminoacyl-tRNA synthetase pair for the in vivo incorporation of unnatural amino acids into proteins.  122:5010-5011. 2000
  • Reconstructing aldolase antibodies to alter their substrate specificity and turnover.  122:4835-4836. 2000
  • Synthesis and assembly of self-complementary cavitands.  122:4573-4582. 2000
  • Chemoenzymatic synthesis of a PSGL-1 N-terminal glycopeptide containing tyrosine sulfate and α-O-linked sialyl Lewis X.  122:4241-4242. 2000
  • Diversity and selection in self-assembled tetrameric capsules.  122:4251-4252. 2000
  • Total synthesis of the novel immunosuppressant sanglifehrin a.  122:3830-3838. 2000
  • A highly efficient method for site-specific modification of unprotected peptides after chemical synthesis.  122:3567-3573. 2000
  • Efforts toward the expansion of the genetic alphabet: information storage and replication with unnatural hydrophobic base pairs.  122:3274-3287. 2000
  • Antibody-catalysis of a bimolecular asymmetric 1,3-dipolar cycloaddition reaction.  122:3244-3245. 2000
  • Biomimetic total synthesis of bisorbicillinol, bisorbibutenolide, trichodimerol, and designed analogues of the bisorbicillinoids.  122:3071-3079. 2000
  • Carbene complexes in the synthesis of complex natural products: total synthesis of the calphostins.  122:3224-3225. 2000
  • A novel strategy for the solid-phase synthesis of substituted indolines.  122:2966-2967. 2000
  • Total syntheses of thiocoraline and be-22179: Establishment of relative and absolute stereochemistry.  122:2956-2957. 2000
  • Molecular dynamics simulations of nucleic acids with a generalized born solvation model.  122:2489-2498. 2000
  • RNA cleavage by a DNA enzyme with extended chemical functionality.  122:2433-2439. 2000
  • Proline-catalyzed direct asymmetric aldol reactions.  122:2395-2396. 2000
  • Structure-based design of N-phenyl phenoxazine transthyretin amyloid fibril inhibitors.  122:2178-2192. 2000
  • RNA Diels-Alderases: relationships between unique sequences and catalytic function.  122:1015-1021. 2000
  • Tyrosine sulfation on a psgl-1 glycopeptide influences the reactivity of glycosyltransferases responsible for synthesis of the attached o-glycan.  122:742-743. 2000
  • Antibodies mimic natural oxidosqualene-cyclase action in steroid ring a formation.  122:40-45. 2000
  • First synthesis of a bidesmosidic triterpene saponin by a highly efficient procedure.  121:12196-12197. 1999
  • Photoinduced protein cross-linking mediated by palladium porphyrins.  121:11896-11897. 1999
  • Sequence selectivity of 3-hydroxypyrrole/pyrrole ring pairings in the DNA minor groove.  121:11621-11629. 1999
  • Efforts toward expansion of the genetic alphabet: DNA polymerase recognition of a highly stable, self-fairing hydrophobic base.  121:11585-11586. 1999
  • Total synthesis and comparative evaluation of luzopeptin A-C and quinoxapeptin A-C.  121:11375-11383. 1999
  • Kinetically stable caviplexes in water.  121:11253-11254. 1999
  • Transfer of chiral information through molecular assembly.  121:11156-11163. 1999
  • Catalytically distinct antibodies prepared by the reactive immunization versus transition state analogue hapten manifolds.  121:10461-10467. 1999
  • Chiral microenvironments in self-assembled capsules.  121:10281-10285. 1999
  • Selective antibody-catalyzed solvolysis of endo-2-norbornyl mesylate.  121:10227-10228. 1999
  • Antibody-metalloporphyrin catalytic assembly mimics natural oxidation enzymes.  121:8978-8982. 1999
  • A model for hydride transfer in thymidylate synthase based on unnatural amino acid mutagenesis.  121:7965-7966. 1999
  • Nitrogen-halogen intermolecular forces in solution.  121:7973-7974. 1999
  • Printing small molecules as microarrays and detecting protein-ligand interactions en masse.  121:7967-7968. 1999
  • A catalytic enantioselective route to hydroxy-substituted quaternary carbon centers: Resolution of tertiary aldols with a catalytic antibody.  121:7283-7291. 1999
  • Encapsulation of ion-molecule complexes: Second-sphere supramolecular chemistry.  121:7455-7456. 1999
  • Self-complementary cavitands.  121:7459-7460. 1999
  • Structural dynamics in the guanylate cyclase heme pocket after co photolysis.  121:7397-7400. 1999
  • Self-assembling peptidomimetic monolayer nucleates oriented CdS nanocrystals.  121:7266-7267. 1999
  • Design and synthesis of new aminoglycoside antibiotics containing neamine as an optimal core structure: Correlation of antibiotic activity with in vitro inhibition of translation.  121:6527-6541. 1999
  • Signaling of escherichia coli enterotoxin on supramolecular redox bilayer vesicles.  121:6767-6768. 1999
  • Selection of human metalloantibodies from a combinatorial phage single-chain antibody library.  121:6517-6518. 1999
  • Conformationally assisted protein ligation using C-terminal thioester peptides.  121:6332-6333. 1999
  • Total synthesis of HUN-7293.  121:6197-6205. 1999
  • Binding-induced activation of DNA alkylation by duocarmycin SA: Insights from the structure of an indole derivative-DNA adduct.  121:5645-5652. 1999
  • The allyl leaving group approach to tricoordinate silyl, germyl, and stannyl cations.  121:5001-5008. 1999
  • Stereochemical relationships between encapsulated molecules.  121:4928-4929. 1999
  • Investigating molecular recognition by mass spectrometry: Characterization of calixarene-based self-assembling capsule hosts with charged guests.  121:4568-4579. 1999
  • Lipoic acid biosynthesis: Lipa is an iron-sulfur protein.  121:4706-4707. 1999
  • Synthesis of the fully functionalized bicyclic core of garsubellin A.  121:4724-4725. 1999
  • Characteristics of an RNA Diels-Alderase active site.  121:3614-3617. 1999
  • A highly stereoselective synthesis of 2-deoxy-beta-glycosides using 2-deoxy-2-iodo-glucopyranosyl acetate donors.  121:3541-3542. 1999
  • Diastereoselective total synthesis of the vancomycin aglycon with ordered atropisomer equilibrations.  121:3226-3227. 1999
  • Structural study on O-glycopeptides: Glycosylation-induced conformational changes of O-GlcNAc, O-LacNAc, O-Sialyl-LacNAc, and O-Sialyl-Lewis-X peptides of the mucin domain of madcam-1.  121:2409-2417. 1999
  • Total synthesis of phomazarin.  121:2471-2477. 1999
  • Characterization of self-assembling encapsulation complexes in the gas phase and solution.  121:2133-2138. 1999
  • Proton-transfer polymerization: A new approach to hyperbranched polymers.  121:2313-2314. 1999
  • C-13 NMR flux ratio analysis of escherichia coli central carbon metabolism in microaerobic bioprocesses.  121:1407-1408. 1999
  • Crystalline cyclic peptide nanotubes at interfaces.  121:1186-1191. 1999
  • Cycle polyamide motif for recognition of the minor groove of DNA.  121:1121-1129. 1999
  • Development of a new type of protease inhibitors, efficacious against FIV and HIV variants.  121:1145-1155. 1999
  • Total synthesis of luzopeptins A-C.  121:1098-1099. 1999
  • De novo design of protein function: Predictable structure-function relationships in synthetic redox proteins.  121:858-859. 1999
  • Programmable one-pot oligosaccharide synthesis.  121:734-753. 1999
  • Trosy-type triple-resonance experiments for sequential NMR assignments of large proteins.  121:844-848. 1999
  • Affinity and specificity of multiple hydroxypyrrole/pyrrole ring pairings for coded recognition of DNA.  121:260-261. 1999
  • Total syntheses of ningalin A, lamellarin O, lukianol A, and permethyl storniamide A utilizing heterocyclic azadiene Diels-Alder reactions.  121:54-62. 1999
  • Total synthesis of olivomycin A.  121:1990-1991. 1999
  • Total synthesis of the vancomycin aglycon.  121:10004-10011. 1999
  • Kinetic implications of nonlinear effects in asymmetric synthesis.  120:13349-13353. 1998
  • A synthetic retrotransition (backward reading) sequence of the right-handed three-helix bundle domain (10-53) of protein a shows similarity in conformation as predicted by computation.  120:13042-13045. 1998
  • A light-activated antibody catalyst.  120:12783-12790. 1998
  • Self-folding cavitands.  120:12216-12225. 1998
  • Macroporous p-type silicon fabry-perot layers. Fabrication, characterization, and applications in biosensing.  120:12108-12116. 1998
  • Critical role of the linking amide in CC-1065 and the duocarmycins: implications on the source of DNA alkylation catalysis.  120:11554-11557. 1998
  • Glycosylation of threonine of the repeating unit of RNA polymerase II with beta-linked N-acetylglucosame leads to a turnlike structure.  120:11567-11575. 1998
  • Total synthesis of mucocin.  120:11279-11284. 1998
  • Solid and solution phase synthesis and biological evaluation of combinatorial sarcodictyin libraries.  120:10814-10826. 1998
  • Vinyl sulfonate esters and vinyl sulfonamides: potent, irreversible inhibitors of cysteine proteases.  120:10994-10995. 1998
  • Snar cyclizations to form cyclic peptidomimetics of beta-turns.  120:10768-10769. 1998
  • Soluble supports tailored for organic synthesis: Parallel polymer synthesis via sequential normal/living free radical processes.  120:9481-9495. 1998
  • A systematic evaluation of the bleomycin A(2) L-threonine side chain: its role in preorganization of a compact conformation implicated in sequence-selective DNA cleavage.  120:9139-9148. 1998
  • Definition of the effect and role of the bleomycin A(2) valerate substituents: preorganization of a rigid, compact conformation implicated in sequence-selective DNA cleavage.  120:9149-9158. 1998
  • Cylindrical beta-sheet peptide assemblies.  120:8949-8962. 1998
  • Subtle functional interactions in the RNA minor groove at a nonessential base pair.  120:9110-9111. 1998
  • Thermal atropisomerism of aglucovancomycin derivatives: preparation of (M,M,M)- and (P,M,M)-aglucovancomycins.  120:8920-8926. 1998
  • Total synthesis of eleutherobin and eleuthosides A and B.  120:8674-8680. 1998
  • Total synthesis of sarcodictyins A and B.  120:8661-8673. 1998
  • A library approach to the discovery of small molecules that recognize rna: Use of a 1,3-hydroxyamine motif as core.  120:8319-8327. 1998
  • Synthesis and screening of linear and cyclic oligocarbamate libraries. Discovery of high affinity ligands for gpiib/iiia.  120:7706-7718. 1998
  • Enantioselective total synthesis of (-)-chlorothricolide via the tandem inter- and intramolecular Diels-Alder reaction of a hexaenoate intermediate.  120:7411-7419. 1998
  • Multistep convergent solution-phase combinatorial synthesis and deletion synthesis deconvolution.  120:7220-7225. 1998
  • Self-assembled molecular capsule catalyzes a Diels-Alder reaction.  120:7389-7390. 1998
  • Solution structure of the complex between the head-to-tail dimer of calicheamicin gamma(i)(1) oligosaccharide and a DNA duplex containing d(acct) and d(tcct) high-affinity binding sites.  120:7183-7191. 1998
  • Structure of the michaelis complex of an efficient antibody acyl transferase determined by transferred nuclear overhauser enhancement spectroscopy.  120:7395-7396. 1998
  • Assembly of oligosaccharide libraries with a designed building block and an efficient orthogonal protection-deprotection strategy.  120:7137-7138. 1998
  • Bispheric coordinative structuring in a zinc finger protein: NMR analysis of a point mutant of the carboxy terminal LIM domain of quail cysteine and glycine rich protein CRP2.  120:7127-7128. 1998
  • Energetic analysis of an engineered cation-π interaction in Staphylococcal nuclease.  120:7135-7136. 1998
  • Bromine-catalyzed aziridination of olefins. A rare example of atom-transfer redox catalysis by a main group element.  120:6844-6845. 1998
  • Synthesis of the first 2',6 bridged penams.  120:6846-6847. 1998
  • Aliphatic/aromatic amino acid pairings for polyamide recognition in the minor groove of DNA.  120:6219-6226. 1998
  • Transverse relaxation-optimized spectroscopy (trosy) for NMR studies of aromatic spin systems in c-13-labeled proteins.  120:6394-6400. 1998
  • Dynamics of assembly and guest exchange in the tennis ball.  120:6193-6194. 1998
  • Segmental isotope labeling for protein NMR using peptide splicing.  120:5591-5592. 1998
  • Mechanistic studies of an antibody-catalyzed elimination reaction.  120:5160-5167. 1998
  • "Deep-cavity" resorcinarenes dimerize through hydrogen bonding and self-inclusion.  120:4977-4981. 1998
  • Convergent functional groups: Intramolecular acyl transfer through a 34-membered ring.  120:5120-5121. 1998
  • Solid phase synthesis of macrocycles by an intramolecular ketophosphonate reaction. Synthesis of a (dl)-muscone library.  120:5132-5133. 1998
  • Oriented self-assembly of cyclic peptide nanotubes in lipid membranes.  120:4417-4424. 1998
  • Total synthesis of goniocin and cyclogoniodenin t. Unique biosynthetic implications.  120:4017-4018. 1998
  • Diels-Alder reactions through reversible encapsulation.  120:3650-3656. 1998
  • Formation of discrete, functional assemblies and informational polymers through the hydrogen-bonding preferences of calixarene aryl and sulfonyl tetraureas.  120:3657-3663. 1998
  • Noncovalent assembly of microhelix recognition by a class II tRNA synthetase.  120:3269-3270. 1998
  • Aldolase antibodies of remarkable scope.  120:2768-2779. 1998
  • Cofactor-induced refinement of catalytic antibody activity: A metal-specific allosteric effect.  120:2963-2964. 1998
  • Direct selection for catalysis from combinatorial antibody libraries using a boronic acid probe: Primary amide bond hydrolysis.  120:2211-2217. 1998
  • NMR studies of Co.deglycoBleomycin A2 green and its complex with d(CCAGGCCTGG).  120:2239-2250. 1998
  • Mechanistic studies of an antibody-catalyzed pericyclic rearrangement.  120:1945-1958. 1998
  • Probing the specificity of aminoglycoside ribosomal rna interactions with designed synthetic analogs.  120:1965-1978. 1998
  • Solution- and solid-phase synthesis of n-protected glycopeptide esters of the benzyl type as substrates for subtilisin-catalyzed glycopeptide couplings.  120:1979-1989. 1998
  • From styrenes to enantiopure alpha-arylglycines in two steps.  120:1207-1217. 1998
  • Total synthesis of nothapodytine B and (-)-mappicine.  120:1218-1222. 1998
  • Measurement of deoxyribose (3)j(hh) scalar couplings reveals protein binding-induced changes in the sugar puckers of the DNA.  120:821-822. 1998
  • Self-assembling cyclic beta(3)-peptide nanotubes as artificial transmembrane ion channels.  120:651-656. 1998
  • Structural rules governing self-assembly emerge from new molecular capsules.  120:819-820. 1998
  • Analysis of the role of the active site tyrosine in human glutathione transferase A1-1 by unnatural amino acid mutagenesis.  120:451-452. 1998
  • Trapping of the C5 methylene intermediate in thymidylate synthase.  120:449-450. 1998
  • Assessment of the role of the bleomycin A(2) pyrimidoblamic acid C4 amino group.  120:53-65. 1998
  • Chiral capsules. 1. Softballs with asymmetric surfaces bind camphor derivatives.  120:66-69. 1998
  • Rules of stereoselectivity in tandem oxidative polycyclization reaction with rhenium(vii) oxides.  120:9076-9077. 1998
  • Mathematical models of nonlinear effects in asymmetric catalysis: new insights based on the role of reaction rate.  119:12934-12939. 1997
  • Analysis of backbone hydrogen bonding in a beta-turn of Staphylococcal nuclease.  119:12667-12668. 1997
  • Chiral capsules: asymmetric binding in calixarene-based dimers.  119:12671-12672. 1997
  • Preparation of specifically deuterated and 13C-labeled RNA for NMR studies using enzymatic synthesis.  119:12100-12108. 1997
  • Rhodium-catalyzed intramolecular silylformylation of alkenes.  119:12416-12417. 1997
  • A new method for the synthesis of fluoro-carbohydrates and glycosides using selectfluor.  119:11743-11746. 1997
  • Enzymatic synthesis of beta-hydroxy-alpha-amino acids based on recombinant d- and l-threonine aldolases.  119:11734-11742. 1997
  • Tandem oxidative cyclization with rhenium oxide. Total synthesis of 17,18-bisepi-goniocin.  119:12014-12015. 1997
  • Ring inversion dynamics of encapsulated cyclohexane.  119:11701-11702. 1997
  • Bis(trimethylsilyl) peroxide extends the range of oxorhenium catalysts for olefin epoxidation.  119:11536-11537. 1997
  • Density functional study on the electronic structures of model peroxidase compounds I and II.  119:11442-11451. 1997
  • Diffusion-limited size-selective ion sensing based on sam-supported peptide nanotubes.  119:11306-11312. 1997
  • Synthesis of the tricyclic core of eleutherobin and sarcodictyins and total synthesis of sarcodictyin a.  119:11353-11354. 1997
  • Total synthesis of (+)-damavaricin D.  119:11331-11332. 1997
  • Mechanism of inactivation of neuronal nitric oxide synthase by n-omega-allyl-l-arginine.  119:10888-10902. 1997
  • Reactive immunization strategy generates antibodies with high catalytic proficiencies.  119:10251-10252. 1997
  • Total syntheses of epothilones a and b.  119:10073-10092. 1997
  • Experimental and theoretical kinetic isotope effects for asymmetric dihydroxylation. Evidence supporting a rate-limiting ''(3+2)'' cycloaddition.  119:9907-9908. 1997
  • Intramolecular hydrogen bonding controls the exchange rates of guests in a cavitand.  119:9911-9912. 1997
  • Measurement of (3)j(c2'p) scalar couplings in a 17 kda protein complex with c-13,n-15-labeled DNA distinguishes the b-i and b-ii phosphate conformations of the DNA.  119:9901-9902. 1997
  • Chemoenzymatic solution- and solid-phase synthesis of o-glycopeptides of the mucin domain of madcam-1. A general route to o-lacnac, o-sialyl-lacnac, and o-sialyl-lewis-x peptides.  119:8766-8776. 1997
  • New synthetic technology for the stereocontrolled construction of 1,1'-disaccharides and 1,1':1'',2-trisaccharides. Synthesis of the fg ring system of everninomicin 13,384-1.  119:9057-9058. 1997
  • Variation in strength of an unconventional C-H to O hydrogen bond in an engineered protein cavity.  119:9083-9084. 1997
  • Synthesis of prostaglandin E-2 methyl ester on a soluble-polymer support for the construction of prostanoid libraries.  119:8724-8725. 1997
  • 3D 15N−13C−13C chemical shift correlation spectroscopy in rotating solids.  119:8540-8546. 1997
  • Chemoenzymatic preparation of novel cyclic imine sugars and rapid biological activity evaluation using electrospray mass spectrometry and kinetic analysis.  119:8146-8151. 1997
  • Small molecules as structural and functional mimics of sialyl Lewis X tetrasaccharide in selectin inhibition: A remarkable enhancement of inhibition by additional negative charge and/or hydrophobic group.  119:8152-8158. 1997
  • Synthesis and cation-mediated electronic interactions of two novel classes of porphyrin-fullerene hybrids.  119:8363-8364. 1997
  • Antibody-catalyzed enantioselective robinson annulation.  119:8131-8132. 1997
  • Methods for the chemical synthesis and readout of self-encoded arrays of polypeptide analogues.  119:7917-7927. 1997
  • New synthetic technology for the construction of 9-membered ring cyclic ethers. Construction of the EFGH ring skeleton of brevetoxin a.  119:8105-8106. 1997
  • The olefin metathesis approach to epothilone a and its analogues.  119:7960-7973. 1997
  • Total syntheses of epothilones A and B via a macrolactonization-based strategy.  119:7974-7991. 1997
  • Recognition of seven base pair sequences in the minor groove of DNA by ten-ring pyrrole-imidazole polyamide hairpins.  119:7636-7644. 1997
  • Highly selective Lewis acid catalyzed Diels-Alder reactions of acyclic (Z)-1,3-dienes.  119:7402-7403. 1997
  • Mutational analysis of backbone hydrogen bonds in Staphylococcal nuclease.  119:7151-7152. 1997
  • Formation of bridge-methylated decalins by antibody-catalyzed tandem cationic cyclization.  119:5993-5998. 1997
  • Highly efficient epoxidation of olefins using aqueous h2o2 and catalytic methyltrioxorhenium/pyridine: Pyridine-mediated ligand acceleration.  119:6189-6190. 1997
  • X-ray absorption studies on the mixed-valence and fully reduced forms of the soluble cu-a domains of cytochrome c oxidase.  119:6135-6143. 1997
  • Palladium-catalyzed functionalization of lactones via their cyclic ketene acetal phosphates. Efficient new synthetic technology for the construction of medium and large cyclic ethers.  119:5467-5468. 1997
  • First evidence that the mechanism of catalytic hydrogenation with homogeneous palladium and rhodium catalysts is strongly influenced by substrate polarity.  119:5257-5258. 1997
  • Computational study of the role of solvation effects in reverse turn formation in the tetrapeptides APGD and APGN.  119:4964-4971. 1997
  • Duocarmycin SA shortened, simplified, and extended agents: A systematic examination of the role of the DNA binding subunit.  119:4977-4986. 1997
  • Reversed and sandwiched analogs of duocarmycin SA: Establishment of the origin of the sequence-selective alkylation of DNA and new insights into the source of catalysis.  119:4987-4998. 1997
  • Modulation of reactivity in native chemical ligation through the use of thiol additives.  119:4325-4329. 1997
  • A pentacoordinate oxorhenium(V) metallochelate elicits antibody catalysts for phosphodiester cleavage.  119:4088-4089. 1997
  • Deconvolution of combinatorial oligonucleotide libraries by electrospray ionization tandem mass spectrometry.  119:3861-3867. 1997
  • Exploitation of subtilisin bpn' as catalyst for the synthesis of peptides containing noncoded amino acids, peptide mimetics and peptide conjugates.  119:3942-3947. 1997
  • Deuterium relaxation in a uniformly n-15-labeled homeodomain and its DNA complex.  119:3842-3843. 1997
  • Direct observation of aminoglycoside-RNA interactions by surface plasmon resonance.  119:3641-3648. 1997
  • An antibody-catalyzed selenoxide elimination.  119:3623-3624. 1997
  • Highly efficient ring closure of aromatic dialdehydes to macrocyclic allenes.  119:3429-3433. 1997
  • New synthetic technology for the synthesis of aryl ethers: Construction of c-o-d and d-o-e ring model systems of vancomycin.  119:3421-3422. 1997
  • Enzymatic glycoprotein synthesis: Preparation of ribonuclease glycoforms via enzymatic glycopeptide condensation and glycosylation.  119:2114-2118. 1997
  • Toward an understanding of the high enantioselectivity in the osmium-catalyzed asymmetric dihydroxylation .4. Electronic effects in amine-accelerated osmylations.  119:1840-1858. 1997
  • A permutation test for stabilization of polypeptide helices by sequence-dependent side chain interactions: Characterization of a helix initiation site within the myohemerythrin sequence 76-87.  119:1153-1154. 1997
  • Influenza neuraminidase inhibitors possessing a novel hydrophobic interaction in the enzyme active site: Design, synthesis, and structural analysis of carbocyclic sialic acid analogues with potent anti-influenza activity.  119:681-690. 1997
  • A general and highly efficient solid phase synthesis of oligosaccharides. Total synthesis of a heptasaccharide phytoalexin elicitor (HPE).  119:449-450. 1997
  • Total synthesis of (+)-duocarmycin A, epi-(+)-duocarmycin A and their unnatural enantiomers: assessment of chemical and biological properties.  119:311-325. 1997
  • Synthesis and assembly of new molecular hosts: solvation and the energetics of encapsulation.  119:77-85. 1997
  • Antibody catalysis of b(ac)2 aryl carbamate ester hydrolysis: A highly disfavored chemical process.  119:2315-2316. 1997
  • A new class of pentacoordinate ribonuclease inhibitors: Synthesis, characterization, and inhibition studies of ribonucleoside and anhydropentofuranose oxorhenium(V) complexes.  118:12521-12527. 1996
  • Copying nature's mechanism for the decarboxylation of β-keto acids into catalytic antibodies by reactive immunization.  118:11720-11724. 1996
  • An antibody-catalyzed 2,3-elimination reaction.  118:11686-11687. 1996
  • Antibody catalyzed terpenoid cyclization.  118:11654-11655. 1996
  • Diffusion filters for separation of solvent-protein and protein-protein nuclear overhauser effects (hydra).  118:11629-11634. 1996
  • The cua center of a soluble domain from thermus cytochrome ba(3). An NMR investigation of the paramagnetic protein.  118:11658-11659. 1996
  • Collagen-based structures containing the peptoid residue n-isobutylglycine (nleu) .6. Conformational analysis of gly-pro-nleu sequences by h-1 NMR, cd, and molecular modeling.  118:10725-10732. 1996
  • Collagen-like triple helices incorporating peptoid residues.  118:10928-10929. 1996
  • Acetyl-terminated and template-assembled collagen-based polypeptides composed of gly-pro-hyp sequences .2. Synthesis and conformational analysis by circular dichroism, ultraviolet absorbance, and optical rotation.  118:10351-10358. 1996
  • Acetyl-terminated and template-assembled collagen-based polypeptides composed of gly-pro-hyp sequences .3. Conformational analysis by h-1-NMR and molecular modeling studies.  118:10359-10364. 1996
  • An olefin metathesis based strategy for the construction of the JKL, OPQ, and UVW ring systems of maitotoxin.  118:10335-10336. 1996
  • Rapid combinatorial synthesis of aminoglycoside antibiotic mimetics: Use of a polyethylene glycol-linked amine and a neamine-derived aldehyde in multiple component condensation as a strategy for the discovery of new inhibitors of the hiv rna rev responsive element.  118:10150-10155. 1996
  • Solid-phase synthesis of 6-deoxyoligosaccharides.  118:9998-9999. 1996
  • Tetramethoxy calix[4]arenes revisited: conformational control through self-assembly.  118:10002-10003. 1996
  • Rational design and synthesis of a 1,1-linked disaccharide that is 5 times as active as sialyl lewis x in binding to e-selectin.  118:9265-9270. 1996
  • A re-examination of two linear pentapeptides claimed to be serine protease mimics.  118:8787-8790. 1996
  • Solution structure of the head-to-head dimer of calicheamicin oligosaccharide domain and d(cgtaggatatcctacg)(2).  118:8817-8824. 1996
  • Synthesis, X-ray structure, and properties of fluorocyclopropane analogs of the duocarmycins incorporating the 9,9-difluoro-1,2,9,9a-tetrahydrocyclopropa c benzo e indol-4-one (F2CBI) alkylation subunit.  118:8860-8870. 1996
  • Distal pocket polarity in the unusual ligand binding site of soluble guanylate cyclase: implications for the control of .NO binding.  118:8769-8770. 1996
  • Energetics of a low barrier hydrogen bond in nonpolar solvents.  118:8575-8579. 1996
  • Preparation of specifically deuterated RNA for NMR studies using a combination of chemical and enzymatic synthesis.  118:7929-7940. 1996
  • Site-specific protein modification using a ketone handle.  118:8150-8151. 1996
  • Useful information from axial peak magnetization in projected NMR experiments.  118:8146-8147. 1996
  • Enzymatic/chemical synthesis and biological evaluation of seven-membered iminocyclitols.  118:7647-7652. 1996
  • Synergistic inhibition of human alpha-1,3-fucosyltransferase v.  118:7653-7662. 1996
  • Soluble polymer-bound ligand-accelerated catalysis: Asymmetric dihydroxylation.  118:7632-7633. 1996
  • Studies on the synthesis of nargenicin A(1): highly stereoselective synthesis of the complete carbon framework via the transannular Diels-Alder reaction of an 18-membered macrolide.  118:7502-7512. 1996
  • A structure-based library approach to kinase inhibitors.  118:7430-7431. 1996
  • Porphyrin metalation catalyzed by a small RNA molecule.  118:7012-7013. 1996
  • Synthesis of sialyl Lewis X mimetics and related structures using the glycosyl phosphite methodology and evaluation of E-selectin inhibition.  118:6826-6840. 1996
  • A 2,3'-substituted biphenyl-based amino acid facilitates the formation of a monomeric beta-hairpin-like structure in aqueous solution at elevated temperature.  118:5836-5845. 1996
  • Antibody-catalyzed retro-aldol reaction.  118:6078-6079. 1996
  • Extending the applicability of native chemical ligation.  118:5891-5896. 1996
  • Inhibition of oleamide hydrolase catalyzed hydrolysis of the endogenous sleep-inducing lipid cis-9-octadecenamide.  118:5938-5945. 1996
  • Antibodies with thiol-S-transferase activity.  118:5474-5475. 1996
  • Probing protein/protein interactions with mass spectrometry and isotopic labeling: Analysis of the p21/cdk2 complex.  118:5320-5321. 1996
  • A template-induced incipient collagen-like triple-helical structure.  118:5156-5157. 1996
  • Cyclic guanidino-sugars with low pKa as transition-state analog inhibitors of glycosidases: Neutral instead of charged species are the active forms.  118:4227-4234. 1996
  • An antibody-catalyzed isomerization reaction.  118:3811-3817. 1996
  • A nitroxyl synthase catalytic antibody.  118:3550-3555. 1996
  • Electrostatic catalysis of the Claisen rearrangement: Probing the role of Glu78 in Bacillus subtilis chorismate mutase by genetic selection.  118:3069-3070. 1996
  • Nature of the potential energy surfaces for the SN1 reaction: A picosecond kinetic study of homolysis and heterolysis for diphenylmethyl chlorides.  118:2992-2997. 1996
  • Total synthesis of swinholide a.  118:3059-3060. 1996
  • Azatides: Solution and liquid phase syntheses of a new peptidomimetic.  118:2539-2544. 1996
  • Novel solution phase strategy for the synthesis of chemical libraries containing small organic molecules.  118:2567-2573. 1996
  • DNA carbohydrate interactions. Specific binding of head-to-head and head-to-tail dimers of the calicheamicin oligosaccharide to duplex DNA.  118:2303-2304. 1996
  • Enantioselective total synthesis of (+)-duocarmycin A, epi-(+)-duocarmycin a, and their unnatural enantiomers.  118:2301-2302. 1996
  • Generalized dipeptidomimetic template: solution phase parallel synthesis of combinatorial libraries.  118:2109-2110. 1996
  • (-)-Sandramycin: total synthesis and characterization of DNA binding properties.  118:1629-1644. 1996
  • A weak calcium binding site in subtilisin BPN' has a dramatic effect on protein stability.  118:1645-1650. 1996
  • Analysis of active site residues in Escherichia coli chorismate mutase by site-directed mutagenesis.  118:1789-1790. 1996
  • Mutagenesis study of active site residues in chorismate mutase from Bacillus subtilis.  118:1787-1788. 1996
  • A re-examination of pressure effects on enantioselectivity in asymmetric catalytic hydrogenation.  118:1348-1353. 1996
  • Olefin metathesis in cyclic ether formation. Direct conversion of olefinic esters to cyclic enol ethers with tebbe-type reagents.  118:1565-1566. 1996
  • Homocarbonates as substrates for the enantioselective enzymatic protection of amines.  118:712-713. 1996
  • Structure determination of an endogenous sleep-inducing lipid, cis-9-octadecenamide (oleamide): A synthetic approach to the chemical analysis of trace quantities of a natural product.  118:580-590. 1996
  • Self-assembling peptide nanotubes.  118:43-50. 1996
  • Toward an understanding of the high enantioselectivity in the osmium-catalyzed asymmetric dihydroxylation .3. New insights into isomeric forms of the putative osmaoxetane intermediate.  118:35-42. 1996
  • Catalytic antibodies with peptidyl-prolyl cis-trans isomerase activity.  118:5496-5497. 1996
  • Synthesis and self-assembly of pseudo-spherical homo- and heterodimeric capsules.  117:12733-12745. 1995
  • Observation of a RuCl2((S)-((-))-tol-binap) (2).N(C2H5)(3)-catalyzed isomerization-hydrogenation network.  117:12647-12648. 1995
  • Total synthesis of granditropone, grandirubrine, imerubrine, and isoimerubrine.  117:12452-12459. 1995
  • Supramolecular design by covalent capture - design of a peptide cylinder via hydrogen-bond-promoted intermolecular olefin metathesis.  117:12364-12365. 1995
  • Selectivity in the inhibition of HIV and FIV protease - inhibitory and mechanistic studies of pyrrolidine-containing alpha-keto amide and hydroxyethylamine core structures.  117:11867-11878. 1995
  • Total synthesis of natural and ent-fredericamycin-a.  117:11839-11849. 1995
  • DNA alkylation properties of CC-1065 and duocarmycin analogs incorporating the 2,3,10,10a-tetrahydrocyclopropa d benzo f quinol-5-one alkylation subunit - identification of subtle structural features that contribute to the regioselectivity of the adenine N3 alkylation reaction.  117:11647-11655. 1995
  • Total synthesis of brevetoxin-b .1. First generation strategies and new approaches to oxepane systems.  117:10227-10238. 1995
  • Total synthesis of brevetoxin-b .2. 2nd generation strategies and construction of the dioxepane region defg.  117:10239-10251. 1995
  • Total synthesis of brevetoxin-b .3. Final strategy and completion.  117:10252-10263. 1995
  • 3(10) helixes in peptides and proteins as studied by modified Zimm-Bragg theory.  117:10098-10103. 1995
  • Metal-catalyzed dehydropolymerization of secondary stannanes to high-molecular-weight polystannanes.  117:9931-9940. 1995
  • Probing the structural determinants of a catalytic RNA with isomerase activity.  117:10145-10146. 1995
  • Antibody catalysis of multistep reactions - an aldol addition followed by a disfavored elimination.  117:9383-9387. 1995
  • Analysis of hydrogen bonding strengths in proteins using unnatural amino acids.  117:9361-9362. 1995
  • Shape and stereoselective cyclopropanation of alkenes catalyzed by iron porphyrins.  117:9194-9199. 1995
  • Structure and dynamics of self-assembling peptide nanotubes and the channel-mediated water organization and self-diffusion - a molecular-dynamics study.  117:9151-9158. 1995
  • Acyl transfer versus catalysis with avidin.  117:8482-8483. 1995
  • An organometallic diradical cycloaromatization reaction.  117:8045-8046. 1995
  • Enzymatic-synthesis and regeneration of 3'-phosphoadenosine 5'-phosphosulfate (PAPS) for regioselective sulfation of oligosaccharides.  117:8031-8032. 1995
  • Sequential 3-substrate and 4-substrate aldol reactions catalyzed by aldolases.  117:7585-7591. 1995
  • Key synthetic analogs of bleomycin A(2) that directly address the effect and role of the disaccharide - demannosylbleomycin A(2) and alpha-D-mannopyranosyldeglycobleomycin A(2).  117:7344-7356. 1995
  • N-desmethyl derivatives of deoxybouvardin and RA-VII: synthesis and evaluation.  117:7364-7378. 1995
  • Solution-phase conformational studies of the cyclic peptide RA-VII: lithium-chloride perturbation of the conformational equilibria.  117:7357-7363. 1995
  • Synthesis and evaluation of the fully functionalized bleomycin A(2) metal-binding domain-containing the 2-O-(3-O-carbamoyl-alpha-D-mannopyranosyl)-alpha-L-gulopyranosyl disaccharide.  117:7338-7343. 1995
  • The streptomyces-glaucescens tcmkl polyketide synthase and tcmn polyketide cyclase genes govern the size and shape of aromatic polyketides.  117:6811-6821. 1995
  • Enzymatic-synthesis of hyaluronic-acid with regeneration of sugar nucleotides.  117:5869-5870. 1995
  • Spectroscopic studies on the designed metal-binding sites of the 43c9 single-chain antibody.  117:5627-5634. 1995
  • Mechanistic studies of antibody-catalyzed pyrimidine dimer photocleavage.  117:5453-5461. 1995
  • Design and synthesis of sialyl-Lewis X mimetics.  117:5395-5396. 1995
  • Studies on the mechanism of action of isoniazid and ethionamide in the chemotherapy of tuberculosis.  117:5009-5010. 1995
  • Catalytic antibodies in organic-synthesis - asymmetric-synthesis of (-)-alpha-multistriatin.  117:3653-3654. 1995
  • Recombinant 2-deoxyribose-5-phosphate aldolase in organic-synthesis - use of sequential 2-substrate and 3-substrate aldol reactions.  117:3333-3339. 1995
  • Remarkable ability of different antibody catalysts to control and diversify the product outcome of cationic cyclization reactions.  117:3308-3309. 1995
  • Sequential one-pot aldol reactions catalyzed by 2-deoxyribose-5-phosphate aldolase and fructose-1,6-diphosphate aldolase.  117:2947-2948. 1995
  • Chemical synthesis and biological evaluation of c-2 taxoids.  117:2409-2420. 1995
  • Oxepane synthesis along a disfavored pathway - the rerouting of a chemical-reaction using a catalytic antibody.  117:2659-2660. 1995
  • Synthesis and efficacy of square planar copper complexes designed to nucleate beta-sheet structure.  117:2533-2546. 1995
  • An antibody-catalyzed nucleophilic-substitution reaction at a primary carbon that appears to proceed by an ionization mechanism.  117:2367-2368. 1995
  • Convergent functional groups. 16. Hydrolysis of phosphate triesters by a novel cleft. Influence of binding on overall rate acceleration.  117:2210-2213. 1995
  • Mechanism of lithium dialkylamide-mediated ketone and imine deprotonations - an mndo study of monomer and open dimer pathways.  117:2166-2178. 1995
  • Studies on the synthesis of aureolic acid antibiotics: highly stereoselective synthesis of aryl 2-deoxy-beta-glycosides via the Mitsunobu reaction and synthesis of the olivomycin A-B disaccharide.  117:2236-2250. 1995
  • The potential application of catalytic antibodies to protecting group removal - catalytic antibodies with broad substrate tolerance.  117:2123-2127. 1995
  • Chemical ligation of cysteine-containing peptides: synthesis of a 22 kDa tethered dimer of HIV-1 protease.  117:1881-1887. 1995
  • Peptidomimetic host that binds a peptide guest affording a beta-sheet structure that subsequently self-assembles. A simple receptor mimic.  117:1655-1656. 1995
  • Combined osmium rhenium approach to synthesis of naturally-occurring polyethers.  117:1447-1448. 1995
  • Macrocyclic peptide inhibitors of serine proteases - convergent total synthesis of cyclotheonamide-a and cyclotheonamide-b via a late-stage primary amine intermediate - study of thrombin inhibition under diverse conditions.  117:1225-1239. 1995
  • Second definitive test of proposed models for the origin of the CC-1065 and duocarmycin DNA alkylation selectivity.  117:1443-1444. 1995
  • A remarkably stable transition-metal benzyne complex - synthesis and structure of cp(pme(3))(eta(2)-c6h4)ta(et(2)c(2)b(4)h(4))(1).  117:1163-1164. 1995
  • Linear free-energy analysis of hydrogen-bonding in proteins.  117:1157-1158. 1995
  • Total synthesis of brevetoxin-b .1. Cdefg framework.  117:1171-1172. 1995
  • Total synthesis of brevetoxin-b .2. Completion.  117:1173-1174. 1995
  • Total synthesis of taxol .1. Retrosynthesis, degradation, and reconstitution.  117:624-633. 1995
  • Total synthesis of taxol .3. Formation of taxols abc ring skeleton.  117:645-652. 1995
  • Total synthesis of taxol .4. The final stages and completion of the synthesis.  117:653-659. 1995
  • Control of self-assembly and reversible encapsulation of xenon in a self-assembling dimer by acid-base chemistry.  117:85-88. 1995
  • Ligand recognition by e-selectin - synthesis, inhibitory activity, and conformational-analysis of bivalent sialyl-lewis-x analogs.  117:66-79. 1995
  • Anti-metallocene antibodies: A new approach to enantioselective catalysis of the Diels-Alder reaction.  117:7041-7047. 1995
  • Base-analog-induced aminoacylation of an RNA helix by a tRNA synthetase.  117:7253-7254. 1995
  • Total synthesis of taxol .2. Construction of a-ring and c-ring intermediates and initial attempts to construct the abc ring-system.  117:634-644. 1995
  • Density-functional Poisson-Boltzmann calculations of redox potentials for iron-sulfur clusters.  116:11898-11914. 1994
  • Differential side chain hydration in a linear peptide containing a type VI turn.  116:12051-12052. 1994
  • Design, synthesis, and evaluation of CC-1065 and duocarmycin analogs incorporating the 2,3,10,10a-tetrahydro-1H-cyclopropa d benzo f quinol-5-one (CBQ) alkylation subunit - identification and structural origin of subtle stereoelectronic features that govern reactivity and regioselectivity.  116:11335-11348. 1994
  • Intracomplex catalysis of acylation reactions.  116:11592-11593. 1994
  • Solution-phase and solid-phase synthesis of inhibitors of helicobacter-pylori attachment and e-selectin-mediated leukocyte adhesion.  116:11315-11322. 1994
  • Total synthesis of crystalline (+/-)-fredericamycin A. Use of radical spirocyclization.  116:11275-11286. 1994
  • Evidence for a cyclic mechanism in (eta(3)-allyl)palladium chemistry - promotion of beta-hydride elimination by unsaturated organometallics.  116:11151-11152. 1994
  • Intramolecular benzannulation reactions of chromium siloxycarbene complexes - regiochemical control and the xenochemical effect of alkyne additives.  116:10921-10933. 1994
  • Channel-mediated transport of glucose across lipid bilayers.  116:10785-10786. 1994
  • Role of geometrical factors in template effects.  116:10296-10297. 1994
  • Lithium dialkylamide mixed aggregation - an NMR spectroscopic study of the influence of hexamethylphosphoramide (hmpa).  116:9198-9202. 1994
  • Lithium dialkylamide mixed aggregation - mndo computational study of salt and solvent dependencies.  116:9187-9197. 1994
  • Total synthesis of truncated brevetoxin-b afghijk.  116:9371-9372. 1994
  • New evidence for template effects in a self-replicating system.  116:8823-8824. 1994
  • Sequence-corrected n-15 random coil chemical-shifts.  116:8466-8469. 1994
  • Total synthesis of bouvardin, O-methylbouvardin, and O-methyl-N-9-desmethylbouvardin.  116:8544-8556. 1994
  • Toward an understanding of the high enantioselectivity in the osmium-catalyzed asymmetric dihydroxylation .2. A qualitative molecular mechanics approach.  116:8470-8478. 1994
  • [(Z)-gamma-[(Diisopropylidene-alpha-D-mannopyranosyl)oxy]allyl]tributylstannane: a new chiral reagent for the asymmetric alpha-hydroxyallylation of aldehydes.  116:8536-8543. 1994
  • CBI-TMI - synthesis and evaluation of a key analog of the duocarmycins - validation of a direct relationship between chemical solvolytic stability and cytotoxic potency and confirmation of the structural features responsible for the distinguishing behavior of enantiomeric pairs of agents.  116:7996-8006. 1994
  • Investigation of medium effects in a family of decarboxylase antibodies.  116:7959-7963. 1994
  • Nmr order parameters of biomolecules - a new analytical representation and application to the gaussian axial fluctuation model.  116:8426-8427. 1994
  • Total synthesis of balanol.  116:8402-8403. 1994
  • Unprecedented asymmetric aldol reactions with 3 aldehyde substrates catalyzed by 2-deoxyribose-5-phosphate aldolase.  116:8422-8423. 1994
  • Binding of hapten to a single chain catalytic antibody demonstrated by electrospray mass spectrometry.  116:7937-7938. 1994
  • Mechanistic studies of the oxidation of isoniazid by the catalase peroxidase from Mycobacterium tuberculosis.  116:7425-7426. 1994
  • Engineering subtilisin for peptide coupling - studies on the effects of counterions and site-specific modifications on the stability and specificity of the enzyme.  116:6521-6530. 1994
  • A new route to deoxythiosugars based on aldolases.  116:6191-6194. 1994
  • Chemical and structural comparison of N-BOC-CBQ and N-BOC-CBI - identification and structural origin of an unappreciated but productive stability of the CC-1065 and duocarmycin SA alkylation subunits.  116:6461-6462. 1994
  • Enantioselective total synthesis of (-)-chlorothricolide.  116:6457-6458. 1994
  • Monitoring catalytic activity by immunoassay: implications for screening.  116:6101-6106. 1994
  • Crossing extreme mechanistic barriers by antibody catalysis: Syn elimination to a cis olefin.  116:6013-6014. 1994
  • Nanoscale tubular ensembles with specified internal diameters - design of a self-assembled nanotube with a 13 Å pore.  116:6011-6012. 1994
  • Total synthesis of bleomycin A(2) and related agents .4. Synthesis of the disaccharide subunit - 2-O-(3-O-carbamoyl-alpha-D-mannopyranosyl)-L-gulopyranose and completion of the total synthesis of bleomycin a(2).  116:5647-5656. 1994
  • Total synthesis of bleomycin-A(2) and related agents .1. Synthesis and DNA-binding properties of the extended C-terminus - tripeptide-S, tetrapeptide-S, pentapeptide-S, and related agents.  116:5607-5618. 1994
  • Total synthesis of bleomycin-A(2) and related agents .2. Synthesis of (-)-pyrimidoblamic acid, epi-(+)-pyrimidoblamic acid, (+)-desacetamidopyrimidoblamic acid, and (-)-descarboxamidopyrimidoblamic acid.  116:5619-5630. 1994
  • Total synthesis of bleomycin-A(2) and related agents .3. Synthesis and comparative-evaluation of deglycobleomycin-A(2), epideglycobleomycin-A(2), deglycobleomycin-A(1), and desacetamidodeglycobleomycin, descarboxamidodeglycobleomycin, desmethyldeglycobleomycin, and desimidazolyldeglycobleomycin-A(2).  116:5631-5646. 1994
  • Convergent functional groups. 15. Studies of large and rigid molecular clefts.  116:5145-5149. 1994
  • Role of the CC-1065 and duocarmycin N-2 substituent - validation of a direct relationship between solvolysis chemical-stability and in-vitro biological potency.  116:5523-5524. 1994
  • Synthesis, structure, and reactivity of (mu-oxo)bis(mu-carboxylato)diiron(III) complexes of a dinucleating dicarboxylate ligand, stable models for non-heme diiron protein cores.  116:5196-5205. 1994
  • Transport of adenine mononucleoside and dinucleoside monophosphates across liquid membranes and extraction of oligonucleotides with synthetic carriers.  116:5501-5502. 1994
  • Chemical probe for glycosidic conformation in telomeric DNAs.  116:4479-4480. 1994
  • Carbohydrate minor-groove interactions in the binding of calicheamicin gamma-1(i) to duplex DNA.  116:3709-3715. 1994
  • Hydrophobic cluster formation is necessary for dibenzofuran-based amino acids to function as beta-sheet nucleators.  116:3988-4005. 1994
  • Interaction of calicheamicin with duplex DNA - role of the oligosaccharide domain and identification of multiple binding modes.  116:3697-3708. 1994
  • Mechanistic studies of an antibody-catalyzed elimination reaction.  116:2261-2270. 1994
  • An antibody-catalyzed oxy-Cope rearrangement.  116:2211-2212. 1994
  • An efficient antibody-catalyzed oxygenation reaction.  116:2167-2168. 1994
  • Antibody-catalyzed prodrug activation.  116:2165-2166. 1994
  • Application of eta4-diene iron tricarbonyl complexes in acyclic stereocontrol: asymmetric synthesis of the as-indacene unit of ikarugamycin (a formal total synthesis).  116:2151-2152. 1994
  • Recognition of DNA by synthetic antibodies.  116:2161-2162. 1994
  • Synthesis of novel taxoids.  116:1591-1592. 1994
  • Toward an understanding of the high enantioselectivity in the osmium-catalyzed asymmetric dihydroxylation (ad) .1. Kinetics.  116:1278-1291. 1994
  • A novel and efficient synthesis of neolacto series gangliosides 3'-nlm(1) and 6'nlm(1).  116:1149-1150. 1994
  • Solid-phase chemical-enzymatic synthesis of glycopeptides and oligosaccharides.  116:1135-1136. 1994
  • Stereoselective antibody-catalyzed oxime formation.  116:1145-1146. 1994
  • Antibody-catalyzed activation of unfunctionalized olefins for highly enantioselective asymmetric epoxidation.  116:803-804. 1994
  • Synthesis of carbohydrates via tandem use of the osmium-catalyzed asymmetric dihydroxylation and enzyme-catalyzed aldol addition-reactions.  116:558-561. 1994
  • Creation of a novel biosensor for zinc(II).  116:415-416. 1994
  • Total syntheses of (+)-p-3a, epi-(-)-p-3a, and (-)-desacetamido p-3a.  116:82-92. 1994
  • (+)- and ent-(-)-duocarmycin SA and (+)- and ent-(-)-N-BOC-DSA DNA alkylation properties - alkylation site models that accommodate the offset AT-rich adenine N3 alkylation selectivity of the enantiomeric agents.  116:1635-1656. 1994
  • Self-replicating molecules: a second generation.  116:8877-8884. 1994
  • Water-soluble receptors for cyclic-AMP and their use for evaluating phosphate-guanidinium interactions.  116:3279-3284. 1994
  • De-novo design and synthesis of somatostatin nonpeptide peptidomimetics utilizing beta-d-glucose as a novel scaffolding.  115:12550-12568. 1993
  • The origin of high enantioselectivity in the dihydroxylation of olefins using osmium tetraoxide and cinchona alkaloid catalysts.  115:12226-12227. 1993
  • (-)-sandramycin - total synthesis and preliminary DNA-binding properties.  115:11624-11625. 1993
  • D, l- and meso-isochrysohermidin - total synthesis and interstrand DNA cross-linking.  115:11418-11425. 1993
  • Total synthesis of (+)-piperazinomycin.  115:11426-11433. 1993
  • Synthesis of phospholipid inhibitor conjugates by enzymatic transphosphatidylation with phospholipase-d.  115:10487-10491. 1993
  • Total synthesis of streptonigrone.  115:10733-10741. 1993
  • Reversibility of the duocarmycin-A and SA DNA alkylation reaction.  115:9872-9873. 1993
  • Synthetic methods for the implementation of encoded combinatorial chemistry.  115:9812-9813. 1993
  • Reduced dimensionality in triple-resonance NMR experiments.  115:9307-9308. 1993
  • Total synthesis and preliminary evaluation of (+)-duocarmycin and ent-(-)-duocarmycin SA.  115:9025-9036. 1993
  • Total synthesis of sulfated le(x) and le(a)-type oligosaccharide selectin ligands.  115:8843-8844. 1993
  • Catalytic asymmetric dihydroxylation of tetrasubstituted olefins.  115:8463-8464. 1993
  • Molecular design, chemical synthesis, kinetic-studies, calculations, and biological studies of novel enediynes equipped with triggering, detection, and deactivating devices - model dynemicin-a epoxide and cis-diol systems.  115:7944-7953. 1993
  • Singlet oxygen oxidation of bipyrroles - total synthesis of d,l-isochrysohermidin and meso-isochrysohermidin.  115:8457-8458. 1993
  • The energetic advantage of 5-exo versus 6-endo epoxide openings - a preference overwhelmed by antibody catalysis.  115:8453-8454. 1993
  • Combined use of trans-sialidase and sialyltransferase for enzymatic-synthesis of alpha-neuac2-- 3-beta-gal-or.  115:7862-7863. 1993
  • Kinetic resolution of racemic olefins via asymmetric dihydroxylation.  115:7864-7865. 1993
  • Total synthesis of calicheamicin-gamma-1(i) .1. Synthesis of the oligosaccharide fragment.  115:7593-7611. 1993
  • Total synthesis of calicheamicin-gamma-1(i) .2. Development of an enantioselective route to (-)-calicheamicinone.  115:7612-7624. 1993
  • Total synthesis of calicheamicin-gamma-1(i) .3. The final stages.  115:7625-7635. 1993
  • Convenient total synthesis of a 4-helix TASP molecule by chemoselective ligation.  115:7263-7266. 1993
  • Ligand recognition by e-selectin - analysis of conformation and activity of synthetic monomeric and bivalent sialyl lewis-x analogs.  115:7549-7550. 1993
  • A dramatic ligand effect on the relative reactivities of substituted alkenes with osmium-tetroxide.  115:7047-7048. 1993
  • Characterization of amino-acid side-chain dynamics in a zinc-finger peptide using c-13 NMR-spectroscopy and time-resolved fluorescence spectroscopy.  115:6333-6345. 1993
  • Determination of local ligand conformations in slowly tumbling proteins by homonuclear 2d and 3d NMR - application to heme propionates in leghemoglobin.  115:6238-6246. 1993
  • Enzymatic-synthesis of N-linked and O-linked glycopeptides.  115:5893-5901. 1993
  • Probing the role of lysine 16 in Ras p(21) protein with unnatural amino acids.  115:6414-6415. 1993
  • A highly specific metal-activated catalytic antibody.  115:4906-4907. 1993
  • Antibody-catalyzed enantioselective epoxide hydrolysis.  115:4893-4894. 1993
  • Engineering metal coordination sites into the antibody light-chain.  115:4449-4456. 1993
  • Total synthesis of naturally-occurring acetogenins - solamin and reticulatacin.  115:4891-4892. 1993
  • Antibody-catalyzed hydrolysis of enol ethers.  115:3909-3917. 1993
  • Protein biosynthesis with conformationally restricted amino acids.  115:4359-4360. 1993
  • Total synthesis of rapamycin.  115:4419-4420. 1993
  • Convergent functional groups. 13. High-affinity complexation of adenosine derivatives within induced binding pockets.  115:3548-3557. 1993
  • Design, synthesis, and partial characterization of water-soluble beta-sheets stabilized by a dibenzofuran-based amino acid.  115:3790-3791. 1993
  • Structure of lithium hexamethyldisilazide (lihmds) in the presence of hexamethylphosphoramide (hmpa) - spectroscopic and computational studies of monomers, dimers, and triple ions.  115:3475-3483. 1993
  • Total synthesis of cycloisodityrosine, RA-VII, deoxybouvardin, and N29-desmethyl-RA-VII - identification of the pharmacophore and reversal of the subunit functional roles.  115:3420-3430. 1993
  • Total synthesis of hemibrevetoxin-b and (7a-alpha)-epi-hemibrevetoxin-b.  115:3558-3575. 1993
  • Correlating hydration shell structure with amino acid hydrophobicity.  115:3336-3337. 1993
  • Evidence of ca2+-dependent carbohydrate association through ion spray mass-spectrometry.  115:2877-2881. 1993
  • A catalytic antibody model for plp-dependent decarboxylases.  115:2515-2516. 1993
  • Application of the steric directing group strategy to the stereoselective synthesis of the octahydronaphthalene substructure of kijanolide and tetronolide.  115:2268-2278. 1993
  • Synthesis and use of glycosyl phosphites - an effective route to glycosyl phosphates, sugar nucleotides, and glycosides.  115:2260-2267. 1993
  • Identification of the active catalyst in the rhodium porphyrin-mediated cyclopropanation of alkenes.  115:1656-1660. 1993
  • A novel strategy for synthesis of ganglioside-gm3 using an enzymatically produced sialoside glycosyl donor.  115:1603-1605. 1993
  • Nmr1 detection of hydration water in the intermolecular interface of a protein-DNA complex.  115:1189-1190. 1993
  • Isolation and structure determination of 2-amino-2-deoxyisochorismate - an intermediate in the biosynthesis of anthranilate.  115:816-817. 1993
  • Molecular recognition in water: new receptors for adenine derivatives.  115:797-798. 1993
  • Synthesis of 3-deoxy-d-manno-2-octulosonic acid (kdo) and its analogs based on kdo aldolase-catalyzed reactions.  115:413-421. 1993
  • Catalytic antibodies from combinatorial libraries.  115:357-358. 1993
  • Detection of 2 histidyl ligands to cu-a of cytochrome-oxidase by 35-ghz endor - n-14,15 and cu-63,65 endor studies of the cu-a site in bovine heart cytochrome-aa(3) and cytochrome-caa(3) and cytochrome-ba(3) from thermus-thermophilus.  115:10888-10894. 1993
  • Unusual stereoselectivity in sialic-acid aldolase-catalyzed aldol condensations - synthesis of both enantiomers of high-carbon monosaccharides.  114:10138-10145. 1992
  • Total synthesis of (+)-duocarmycin SA.  114:10056-10058. 1992
  • Chemical-enzymatic synthesis and conformational-analysis of sialyl lewis-x and derivatives.  114:9283-9298. 1992
  • Functional analogs of CC-1065 and the duocarmycins incorporating the 9A-(chloromethyl)-1,2,9,9a-tetrahydrocyclopropa c benz e indol-4-one (C2BI) alkylation subunit - synthesis and preliminary DNA alkylation studies.  114:9318-9327. 1992
  • Redox-controlled bergman cycloaromatizations - designed enediynes with DNA-cleaving properties and antitumor-activity.  114:9279-9282. 1992
  • Molecular design and chemical synthesis of potent enediynes .1. Dynemicin model systems equipped with n-tethered triggering devices.  114:8890-8907. 1992
  • Molecular design and chemical synthesis of potent enediynes .2. Dynemicin model systems equipped with c-3 triggering devices and evidence for quinone methide formation in the mechanism of action of dynemicin-a.  114:8908-8921. 1992
  • Nonpeptidal peptidomimetics with a beta-d-glucose scaffolding - a partial somatostatin agonist bearing a close structural relationship to a potent, selective substance-p antagonist.  114:9217-9218. 1992
  • Beta-sialyl phosphite and phosphoramidite - synthesis and application to the chemoenzymatic synthesis of cmp-sialic acid and sialyl oligosaccharides.  114:8748-8750. 1992
  • Cluster sialoside inhibitors for influenza-virus - synthesis, NMR, and biological studies.  114:8363-8375. 1992
  • Intramolecular benzannulation reactions of manganese carbene complexes.  114:8735-8736. 1992
  • Organotransition-metal metallacarboranes .26. Carborane ligands in organometallic chemistry - a new class of fischer carbene complexes.  114:8733-8735. 1992
  • Total synthesis of the nodrm-iv factors, the rhizobium nodulation signals.  114:8701-8702. 1992
  • A dibenzofuran-based amino acid designed to nucleate antiparallel beta-sheet structure: evidence for intramolecular hydrogen-bond formation.  114:8316-8318. 1992
  • A transition-state model for the rhodium porphyrin-catalyzed cyclopropanation of alkenes by diazo esters.  114:8336-8338. 1992
  • Remarkable regioselectivity in the chemical glycosylation of glycal acceptors - a concise solution to the synthesis of sialyl-lewis-x glycal.  114:8329-8331. 1992
  • Site-specific isotopic labeling of proteins for NMR studies.  114:7959-7961. 1992
  • Total synthesis of hemibrevetoxin-b.  114:7935-7936. 1992
  • Catalytic asymmetric dihydroxylation of cis-disubstituted olefins.  114:7568-7570. 1992
  • DNA carbohydrate interactions - specific binding of the calicheamicin-gamma-1i oligosaccharide with duplex DNA.  114:7555-7557. 1992
  • Design, synthesis, and study of simple monocyclic conjugated enediynes - the 10-membered ring enediyne moiety of the enediyne anticancer antibiotics.  114:7360-7371. 1992
  • Psi PO2-CH2N+ , a new amide bond replacement - potent, slow-binding inhibition of the HIV protease.  114:7604-7606. 1992
  • Selective asymmetric dihydroxylation of dienes.  114:7570-7571. 1992
  • A new chiral auxiliary for asymmetric thermal reactions: high stereocontrol in radical addition, allylation, and annulation reactions.  114:7007-7018. 1992
  • Polypeptide hydration in mixed-solvents at low-temperatures.  114:7093-7095. 1992
  • Specificity, inhibition, and synthetic utility of a recombinant human alpha-1,3-fucosyl-transferase.  114:7321-7322. 1992
  • An antibody-catalyzed dehydration reaction.  114:6573-6574. 1992
  • Novel tight-binding inhibitors of leukotriene-a(4) hydrolase.  114:6552-6553. 1992
  • LCAO X alpha calculation of the magnetic exchange interactions in a Mn(IV)Mn(III)3 cubane complex: relevance to the water oxidation center of photosystem II.  114:6109-6119. 1992
  • DNA alkylation properties of enhanced functional analogs of cc-1065 incorporating the 1,2,9,9a-tetrahydrocyclopropa 1,2-c benz 1,2-e indol-4-one (cbi) alkylation subunit.  114:5487-5496. 1992
  • Conformational studies of sialyl lewis-x in aqueous-solution.  114:5452-5454. 1992
  • Structure and reactivity of lithium diisopropylamide in the presence of n,n,n',n'-tetramethylethylenediamine.  114:5100-5110. 1992
  • Synthetic replicators and extrabiotic chemistry.  114:4529-4532. 1992
  • Defining hydrophobicity: probing the structure of solute-induced hydration shells by Fourier transform infrared spectroscopy.  114:4336-4339. 1992
  • Design of an artificial 4-helix bundle metalloprotein via a novel ruthenium(ii)-assisted self-assembly process.  114:4000-4002. 1992
  • Direct observation of a ternary complex between the dimeric enzyme HIV-1 protease and a substrate-based inhibitor.  114:3992-3993. 1992
  • Overproduction of cmp-sialic acid synthetase for organic-synthesis.  114:3901-3910. 1992
  • Substituent effects on an antibody-catalyzed hydrolysis of phenyl-esters - further evidence for an acyl-antibody intermediate.  114:3528-3534. 1992
  • Enantioselective total synthesis of (-)-calicheamicinone.  114:3134-3136. 1992
  • Total synthesis of sialyl dimeric lex.  114:3126-3128. 1992
  • Determination of structures of solvated lithium dialkylamides by semiempirical (mndo) methods - comparison of theory and experiment.  114:2112-2121. 1992
  • Highly enantioselective protonation catalyzed by an antibody.  114:2257-2258. 1992
  • A chromogenic assay for screening large antibody libraries.  114:1486-1487. 1992
  • A new approach toward the inhibition of ribonucleases - a water-stable ribonucleoside technetium chelate.  114:1488-1489. 1992
  • A convergent approach to protein design - metal ion-assisted spontaneous self-assembly of a polypeptide into a triple-helix bundle protein.  114:825-831. 1992
  • Deoxyribose-5-phosphate aldolase as a catalyst in asymmetric aldol condensation.  114:741-748. 1992
  • Stereospecific antibody-catalyzed reduction of an alpha-keto amide.  114:780-781. 1992
  • Spectroscopic studies of a transcriptional activation peptide.  114:362-363. 1992
  • Novel enediynes equipped with triggering and detection devices - isolation of cis-diol models of the dynemicin-a cascade.  113:9878-9880. 1991
  • A synthetic receptor for dinucleotides.  113:9424-9425. 1991
  • Antibody-catalyzed hydrolysis of phosphate monoesters.  113:9397-9398. 1991
  • Engineering protein specificity: gene manipulation with semisynthetic nucleases.  113:9398-9400. 1991
  • General-approach to the synthesis of short alpha-helical peptides.  113:9391-9392. 1991
  • Sigmoidal growth in a self-replicating system.  113:9422-9423. 1991
  • Kinetic studies and modeling of a self-replicating system.  113:8831-8839. 1991
  • Enantiofacial protonation by catalytic antibodies.  113:8528-8529. 1991
  • Probing the acceptor specificity of beta-1,4-galactosyltransferase for the development of enzymatic-synthesis of novel oligosaccharides.  113:8137-8145. 1991
  • A complete change of stereoselectivity in sialic-acid aldolase reactions - a novel synthetic route to the kdo type of 9-carbon-l sugars.  113:7816-7818. 1991
  • Asymmetric induction via a catalytic antibody.  113:7763-7764. 1991
  • Antibody-catalyzed bimolecular imine formation.  113:6670-6672. 1991
  • Isolation and characterization of the duocarmycin adenine DNA adduct.  113:6645-6649. 1991
  • Palladium-mediated stereocontrolled reductive amination of azido sugars prepared from enzymatic aldol condensation - a general-approach to the synthesis of deoxy aza sugars.  113:6678-6680. 1991
  • A highly efficient multienzyme system for the one-step synthesis of a sialyl trisaccharide - insitu generation of sialic-acid and n-acetyllactosamine coupled with regeneration of udp-glucose, udp-galactose, and cmp-sialic acid.  113:6300-6302. 1991
  • Enzyme-catalyzed aldol condensation for asymmetric-synthesis of azasugars - synthesis, evaluation, and modeling of glycosidase inhibitors.  113:6187-6196. 1991
  • New chiral auxiliary for asymmetric thermal reactions: high regio- and beta-stereoselectivity in asymmetric radical addition reactions to mixed fumarimides.  113:5918-5920. 1991
  • On the structure of lithium 2,2,6,6-tetramethylpiperidide (litmp) and lithium diisopropylamide (lda) in the presence of hexamethylphosphoramide (hmpa) - structure-dependent distribution of cyclic and open dimers, ion triplets, and monomers.  113:5751-5757. 1991
  • Pseudomonas-oleovorans monooxygenase catalyzed asymmetric epoxidation of allyl alcohol derivatives and hydroxylation of a hypersensitive radical probe with the radical ring-opening rate exceeding the oxygen rebound rate.  113:5878-5880. 1991
  • Synthesis of cluster sialoside inhibitors for influenza-virus.  113:5865-5866. 1991
  • Antibody bait and switch catalysis - a survey of antigens capable of inducing abzymes with acyl-transfer properties.  113:5427-5434. 1991
  • New molecular complements to imides. Complexation of thymine derivatives.  113:5125-5127. 1991
  • Enzyme-catalyzed synthesis of sialyl oligosaccharide with insitu regeneration of cmp-sialic acid.  113:4698-4700. 1991
  • Intramolecular motions of a zinc finger DNA-binding domain from xfin characterized by proton-detected natural abundance c-12 heteronuclear NMR-spectroscopy.  113:4371-4380. 1991
  • Proton proton overhauser effects of receptor-bound cyclosporine-a observed with the use of a heteronuclear-resolved half-filter experiment.  113:4676-4678. 1991
  • Kinetic-studies of superoxide dismutases - properties of the manganese-containing protein from thermus-thermophilus.  113:4069-4076. 1991
  • Proton-exchange with internal water-molecules in the protein bpti in aqueous-solution.  113:4363-4364. 1991
  • Total synthesis of (+/-)-cis-trikentrin-A and (+/-)-trans-trikentrin-A - Diels-Alder reactions of heteroaromatic azadienes.  113:4230-4234. 1991
  • (+)-CC-1065 DNA alkylation - key studies demonstrating a noncovalent binding selectivity contribution to the alkylation selectivity.  113:3980-3983. 1991
  • Synthesis and chemistry of dynemicin-a models.  113:3106-3114. 1991
  • (+)-CC-1065 DNA alkylation - observation of an unexpected relationship between cyclopropane electrophile reactivity and the intensity of DNA alkylation.  113:2779-2780. 1991
  • A general and efficient route for chemical aminoacylation of transfer RNAs.  113:2722-2729. 1991
  • Construction of a light-activated protein by unnatural amino acid mutagenesis.  113:2758-2760. 1991
  • Active-site-directed modification of subtilisin.  113:2259-2263. 1991
  • An antibody-catalyzed cis trans isomerization reaction.  113:2319-2321. 1991
  • Soft stereoelectronic effects at carboxyl oxygen.  113:2247-2253. 1991
  • Inverse electron demand Diels-Alder reactions of N-sulfonyl alpha,beta-unsaturated imines - a general-approach to implementation of the 4-pi participation of 1-aza-1,3-butadienes in Diels-Alder reactions.  113:1713-1729. 1991
  • Redirecting the immune response: ligand-mediated immunogenicity.  113:1861-1862. 1991
  • Convergent functional groups create a microenvironment for enolization catalysis.  113:1453-1454. 1991
  • Total synthesis of deoxybouvardin and RA-VII - macrocyclization via an intramolecular Ullmann reaction.  113:1427-1429. 1991
  • Engineering subtilisin for reaction in dimethylformamide.  113:683-684. 1991
  • Epoxyquinones from 2,5-dihydroxyacetanilide - opposite facial specificity in the epoxidation by enzymes from streptomyces ll-c10037 and streptomyces mpp 3051.  113:684-686. 1991
  • Catalytic antibodies with acyl-transfer capabilities - mechanistic and kinetic investigations.  113:291-297. 1991
  • Convergent functional groups. 10. Molecular recognition of neutral substrates.  113:201-209. 1991
  • Mechanism of asymmetric epoxidation .1. Kinetics.  113:106-113. 1991
  • Mechanism of asymmetric epoxidation .2. Catalyst structure.  113:113-126. 1991
  • Peptide architecture - design of stable alpha-helical metallopeptides via a novel exchange-inert ruiii complex.  112:9633-9635. 1990
  • High-efficiency synthesis of sialyloligosaccharides and sialoglycopeptides.  112:9308-9309. 1990
  • Peroxidase activity of an antibody heme complex.  112:9414-9415. 1990
  • Convergent functional groups. 9. Complexation in new molecular clefts.  112:8902-8906. 1990
  • Duocarmycin pyrindamycin DNA alkylation properties and identification, synthesis, and evaluation of agents incorporating the pharmacophore of the duocarmycin pyrindamycin alkylation subunit - identification of the CC-1065-duocarmycin common pharmacophore.  112:8961-8971. 1990
  • Immobilized catalytic antibodies in aqueous and organic-solvents.  112:8886-8888. 1990
  • Use of a double-half-filter in 2-dimensional 1h nuclear-magnetic-resonance studies of receptor-bound cyclosporine.  112:9015-9016. 1990
  • Convergent functional groups. 8. Flexible model receptors for adenine derivatives.  112:8408-8414. 1990
  • Specific deuteration strategy for enhancing direct nuclear overhauser effects in high-molecular-weight complexes.  112:8183-8185. 1990
  • Total synthesis of the oligosaccharide fragment of calicheamicin gamma-1i.  112:8193-8195. 1990
  • DNA cleavage and antitumor-activity of designed molecules with conjugated phosphine oxide-allene-ene-yne functionalities.  112:7825-7826. 1990
  • An antibody-catalyzed bimolecular Diels-Alder reaction.  112:7430-7431. 1990
  • Synthesis of dynemicin-a models.  112:7416-7418. 1990
  • Acyclic diastereoselective synthesis using tartrate ester modified crotylboronates: double asymmetric reactions with alpha-methyl chiral aldehydes and synthesis of the C19-C29 segment of rifamycin S.  112:6348-6359. 1990
  • Asymmetric-synthesis using diisopropyl tartrate modified (E)-crotylboronates and (Z)-crotylboronates: preparation of the chiral crotylboronates and reactions with achiral aldehydes.  112:6339-6348. 1990
  • Synthesis of medium-sized ring ethers from thionolactones - applications to polyether synthesis.  112:6263-6276. 1990
  • Molecular recognition. Asymmetric complexation of diketopiperazines.  112:6144-6145. 1990
  • Enzymes as synthetic catalysts - mechanistic and active-site considerations of natural and modified chymotrypsin.  112:5313-5320. 1990
  • Synthesis of n-(phenylsulfonyl)-CI, N-((tert-butyloxy)carbonyl)-CI, CI-CDPI1, and CI-CDPI2 - CC-1065 functional analogs incorporating the parent 1,2,7,7a-tetrahydrocycloprop 1,2-c indol-4-one (CI) left-hand subunit.  112:5230-5240. 1990
  • Novel stereocontrolled synthesis of the nonacene ring-system of brevetoxin-a - conformational reactivity effects in 9-membered rings.  112:4988-4989. 1990
  • Site-specific cleavage of duplex DNA with a lambda-repressor Staphylococcal nuclease hybrid.  112:4579-4580. 1990
  • Intramolecular acyl radical alkene addition-reactions - macrocyclization reactions.  112:4008-4011. 1990
  • Novel strategy for the construction of the oligosaccharide fragment of calicheamicin-gamma-1-alpha-i - synthesis of the abc skeleton.  112:4085-4086. 1990
  • Tandem free-radical alkene addition-reactions of acyl radicals.  112:4003-4008. 1990
  • New nuclear-magnetic-resonance experiment for measurements of the vicinal coupling-constants 3jhn-alpha in proteins.  112:3663-3665. 1990
  • New synthetic strategies for the construction of medium-size cyclic ethers - stereocontrolled synthesis of the bcd ring framework of brevetoxin-a.  112:3696-3697. 1990
  • Stereoelectronic effects in cyclization reactions.  112:3685-3686. 1990
  • Total synthesis of the tumor-associated le(x) family of glycosphingolipids.  112:3693-3695. 1990
  • A new strategy for selective protein cleavage.  112:3249-3250. 1990
  • Bridging of macrodithionolactones to bicyclic systems - synthesis and modeling of oxapolycyclic frameworks.  112:3040-3054. 1990
  • Dithiatopazine and related systems - synthesis, chemistry, x-ray crystallographic analysis and calculations.  112:3029-3039. 1990
  • Exchange of amide protons. Effect of intramolecular hydrogen bonding.  112:3122-3125. 1990
  • Relative hydrogen-bonding affinities of imides and lactams.  112:3215-3217. 1990
  • Deoxyribose-5-phosphate aldolase as a synthetic catalyst.  112:2013-2014. 1990
  • Secondary structure nucleation in peptides - transition-metal ion stabilized alpha-helices.  112:1630-1632. 1990
  • A self-replicating system.  112:1249-1250. 1990
  • Bait and switch strategy for obtaining catalytic antibodies with acyl-transfer capabilities.  112:1274-1275. 1990
  • Enzymes in organic synthesis: use of subtilisin and a highly stable mutant derived from multiple site-specific mutations.  112:945-953. 1990
  • Synthesis and evaluation of aborted and extended CC-1065 functional analogs - (+)-CPI-PDE-1, and (-)-CPI-PDE-1, (+)-CPI-PDE-1, and (-)-CPI-CDPI1, and (+/-)-CPI-PDE-i1, (+)-CPI-PDE-i1, and (-)-CPI-CDPI3 - preparation of key partial structures and definition of an additional functional-role of the CC-1065 central and right-hand subunits.  112:4623-4632. 1990
  • New chiral auxiliaries for thermal cycloadditions.  111:9238-9240. 1989
  • Aminolysis of benzoyl fluorides in water.  111:8479-8484. 1989
  • Mechanism of solvolysis of substituted benzoyl halides.  111:8470-8479. 1989
  • Sequence-selective hydrolysis of duplex DNA by an oligonucleotide-directed nuclease.  111:8523-8525. 1989
  • Conformational study of cinchona alkaloids - a combined NMR, molecular mechanics, and x-ray approach.  111:8069-8076. 1989
  • Biosynthesis of antibiotic ll-c10037-alpha - the steps beyond 3-hydroxyanthranilic acid.  111:7932-7938. 1989
  • Free-radical cyclizations - application to the total synthesis of dl-pleurotin and dl-dihydropleurotin acid.  111:7507-7519. 1989
  • Synthesis of the abc ring-system of brevetoxin-b.  111:6666-6675. 1989
  • Synthesis of the brevetoxin-b ijk ring-system.  111:6682-6690. 1989
  • Synthesis of the fg ring-system of brevetoxin-b.  111:6676-6682. 1989
  • Total synthesis and evaluation of (+/-)-N-(tert-butyloxycarbonyl)-CBI, (+/-)-CBI-CDPI1, and (+/-)-CBI-CDPI2 - CC-1065 functional agents incorporating the equivalent 1,2,9,9a-tetrahydrocycloprop 1,2-c benz 1,2-e indol-4-one (CBI) left-hand subunit.  111:6461-6463. 1989
  • Stereospecific hydrolysis of alkyl esters by antibodies.  111:5961-5962. 1989
  • Activation of 6-endo over 5-exo hydroxy epoxide openings - stereoselective and ring selective synthesis of tetrahydrofuran and tetrahydropyran systems.  111:5330-5334. 1989
  • Activation of 7-endo over 6-exo epoxide openings - synthesis of oxepane and tetrahydropyran systems.  111:5335-5340. 1989
  • Cyclizations of hydroxy dithioketals - new synthetic technology for the construction of oxocenes and related medium-ring systems.  111:5321-5330. 1989
  • 1,1'-carbonylbis(3-methylimidazolium) triflate: an efficient reagent for aminoacylations.  111:4856-4859. 1989
  • Intramolecular catalysis of enolization: a probe for stereoelectronic effects at carboxyl oxygen.  111:4503-4505. 1989
  • Automated stereospecific h-1-NMR assignments and their impact on the precision of protein-structure determinations in solution.  111:3997-4004. 1989
  • Synthetic studies on the dioxepane region of brevetoxin-b - new synthetic technology for the construction of oxepanes and synthesis of a model for the cdef ring skeleton of brevetoxin-b.  111:4136-4137. 1989
  • Use of a recombinant bacterial fructose-1,6-diphosphate aldolase in aldol reactions - preparative syntheses of 1-deoxynojirimycin, 1-deoxymannojirimycin, 1,4-dideoxy-1,4-imino-d-arabinitol, and fagomine.  111:3924-3927. 1989
  • Neutron-diffraction structure-analysis of a hexanuclear copper hydrido complex, h6cu6 p(para-tolyl)3 6 - an unexpected finding.  111:3472-3473. 1989
  • A highly stereoselective synthesis of (+)-olivin, the aglycon of olivomycin A.  111:2984-2995. 1989
  • Metalloselective anti-porphyrin monoclonal-antibodies.  111:2344-2346. 1989
  • A semisynthetic catalytic antibody.  111:1929-1931. 1989
  • N-h bond length determinations and implications for the gramicidin channel conformation and dynamics from n-15-h-1 dipolar interactions.  111:1910-1912. 1989
  • Studies of protein hydration in aqueous-solution by direct NMR observation of individual protein-bound water-molecules.  111:1871-1875. 1989
  • A general-solution to implementing the 4-p participation of 1-aza-1,3-butadienes in Diels-Alder reactions - inverse electron demand Diels-Alder reactions of alpha,beta-unsaturated n-benzenesulfonyl imines.  111:1517-1519. 1989
  • A mechanistic insight leads to a greatly improved osmium-catalyzed asymmetric dihydroxylation process.  111:1123-1125. 1989
  • Molecular recognition with convergent functional groups. 6. Synthetic and structural studies with a model receptor for nucleic acid components.  111:1082-1090. 1989
  • Molecular recognition with convergent functional groups. 7. Energetics of adenine binding with model receptors.  111:1090-1094. 1989
  • Kinetic role of the alkaloid ligands in asymmetric catalytic dihydroxylation.  111:737-739. 1989
  • Experimental-observation of orientational dispersion in the peptide backbone of the gramicidin cation channel.  111:400-401. 1989
  • Synthesis and characterization of the "chiral wall" porphyrin: a chemically robust ligand for metal-catalyzed asymmetric epoxidations.  111:9116-9117. 1989
  • Antibody catalysis in reverse micelles.  110:8713-8714. 1988
  • A practical and enantioselective synthesis of glycosphingolipids and related-compounds - total synthesis of globotriaosylceramide (gb3).  110:7910-7912. 1988
  • Clean tocsy for h-1 spin system-identification in macromolecules.  110:7870-7872. 1988
  • Photosensitized cleavage of a thymine dimer by an antibody.  110:7888-7890. 1988
  • Vicinal diol cyclic sulfates - like epoxides only more reactive.  110:7538-7539. 1988
  • Allosteric cooperativity and transport: studies in a circulating system.  110:7140-7143. 1988
  • DNA cleavage by a synthetic mimic of the calicheamicin esperamicin class of antibiotics.  110:7247-7248. 1988
  • Lipase-catalyzed irreversible transesterifications using enol esters as acylating reagents - preparative enantioselective and regioselective syntheses of alcohols, glycerol derivatives, sugars, and organometallics.  110:7200-7205. 1988
  • A hybrid sequence-selective ribonuclease S.  110:6592-6594. 1988
  • Enzymes in carbohydrate synthesis - n-acetylneuraminic acid aldolase catalyzed-reactions and preparation of n-acetyl-2-deoxy-d-neuraminic acid-derivatives.  110:6481-6486. 1988
  • Molecular recognition: multipoint contacts with new sizes and shapes.  110:6575-6577. 1988
  • Stereoelectronic effects and the active site of the serine proteases.  110:5908-5909. 1988
  • A new class of chelating agents.  110:5192-5193. 1988
  • A search for peptide ligase: cosolvent-mediated conversion of proteases to esterases for irreversible synthesis of peptides.  110:5162-5166. 1988
  • An antibody-catalyzed Claisen rearrangement.  110:4841-4842. 1988
  • Antibody catalysis of bimolecular amide formation.  110:4835-4837. 1988
  • Chemistry of amphotericin-b - degradation studies and preparation of amphoteronolide-b.  110:4660-4672. 1988
  • Cyclic conjugated enediynes related to calicheamicins and esperamicins - calculations, synthesis, and properties.  110:4866-4868. 1988
  • Novel chemistry of dithiatopazine.  110:4868-4869. 1988
  • Total synthesis of (+/-)-n-2-(phenylsulfonyl)-cpi, (+/-)-cc-1065, (+)-cc-1065, ent-(-)-cc-1065, and the precise, functional agents (+/-)-cpi-cdpi2, (+)-cpi-cdpi2, and (-)-cpi-cdpi2 (+/-)-(3br-star,4as-star)-deoxy-cc-1065, (+)-(3br,4as)-deoxy-cc-1065, and (-)-(3bs,4ar)-deoxy-cc-1065.  110:4796-4807. 1988
  • Total synthesis of amphotericin-b .3. The final stages.  110:4696-4705. 1988
  • Total synthesis of amphoteronolide-b and amphotericin-b .1. Strategy and stereocontrolled construction of key building-blocks.  110:4672-4685. 1988
  • Total synthesis of amphoteronolide-b and amphotericin-b .2. Total synthesis of amphoteronolide-b.  110:4685-4696. 1988
  • Total synthesis of linear polyprenoids .3. Syntheses of ubiquinones via palladium-catalyzed oligomerization of monoterpene monomers.  110:4356-4362. 1988
  • N,N'-dibenzyl-N,N'-ethylenetartramide: a rationally designed chiral auxiliary for the allylboration reaction.  110:3979-3982. 1988
  • Modification of proteases to esterases for peptide-synthesis - methylchymotrypsin.  110:3709-3710. 1988
  • Aluminum dichloride and dibromide - preparation, spectroscopic (including matrix-isolation) study, reactions, and role (together with alkyl(aryl)aluminum monohalides) in the preparation of organo-aluminum compounds.  110:3231-3238. 1988
  • Molecular recognition: hydrogen bonding and aromatic stacking converge to bind cytosine derivatives.  110:3327-3328. 1988
  • Heteronuclear filters for two-dimensional h-1-NMR - identification of the metal-bound amino-acids in metallothionein and observation of small heteronuclear long-range couplings.  110:2388-2393. 1988
  • Antibody catalysis approaching the activity of enzymes.  110:2282-2286. 1988
  • Asymmetric dihydroxylation via ligand-accelerated catalysis.  110:1968-1970. 1988
  • Site-selective cleavage of RNA by a hybrid enzyme.  110:1614-1615. 1988
  • Broken symmetry analysis of spin coupling in iron sulfur clusters.  110:1001-1005. 1988
  • Convergent functional groups. 5. Ternary complexes in the molecular recognition of beta-arylethylamines.  110:923-927. 1988
  • Convergent functional groups: catalysis of hemiacetal cleavage in a synthetic molecular cleft.  110:983-984. 1988
  • Total synthesis of (+)-CC-1065 and ent-(-)-CC-1065.  110:1321-1323. 1988
  • A highly stereoselective total synthesis of the natural enantiomer of olivin.  109:7575-7577. 1987
  • Molecular recognition: Watson-Crick, Hoogsteen, and bifurcated hydrogen bonding in a model for adenine recognition.  109:6866-6867. 1987
  • Kinetic-studies on 1-1 electron-transfer reactions involving blue copper proteins .15. The reactivity of anabaena-variabilis plastocyanin with inorganic complexes and related NMR-studies.  109:6443-6449. 1987
  • Catalytic asymmetric epoxidation and kinetic resolution - modified procedures including insitu derivatization.  109:5765-5780. 1987
  • Triphenylsilyl perchlorate revisited: silicon-29 and chlorine-35 NMR spectroscopy and x-ray crystallography showing covalent nature in both solution and the solid state. Difficulties in observing long-lived silyl cations in the condensed state.  109:5123-5126. 1987
  • Molecular recognition: hydrogen bonding and stacking interactions stabilize a model for nucleic acid structure.  109:5033-5035. 1987
  • Molecular recognition: new shapes for asymmetric microenvironments.  109:4119-4120. 1987
  • Dithiatopazine - the 1st stable 1,2-dithietane.  109:3801-3802. 1987
  • Molecular recognition: size and shape specificity in the binding of dicarboxylic acids.  109:3474-3475. 1987
  • Inhibition of the hydrolysis of para-(dimethylamino)benzoyl fluoride by potassium fluoride.  109:3160-3161. 1987
  • Diels-alder reactions of heterocyclic azadienes - total synthesis of pde-i, pde-ii, and pde-i dimer methyl-ester.  109:2717-2727. 1987
  • Convergent functional groups. 3. A molecular cleft recognizes substrates of complementary size, shape, and functionality.  109:2426-2431. 1987
  • Convergent functional groups. 4. Recognition and transport of amino acids across a liquid membrane.  109:2432-2434. 1987
  • Nucleophilic additions to thionolactones - new synthetic technology for the construction of medium-ring and large-ring ethers.  109:2504-2506. 1987
  • Catalytic antibodies.  109:2174-2176. 1987
  • Stereocontrolled construction of key building-blocks for the total synthesis of amphoteronolide-b and amphotericin-b.  109:2205-2208. 1987
  • Resonance raman-spectra of the 2fe-2s clusters of the rieske protein from thermus and phthalate dioxygenase from pseudomonas.  109:1559-1561. 1987
  • Site-selective observation of nuclear overhauser effects in proteins via isotopic labeling.  109:1591-1593. 1987
  • Protein-structure and interactions by combined use of sequential NMR assignments and isotope labeling.  109:1090-1092. 1987
  • Unexpected diversity in the coordination chemistry of tartrate esters with titanium(iv).  109:1279-1282. 1987
  • Applications of tartrate ester modified allylic boronates in organic-synthesis: an efficient, highly stereoselective synthesis of the C19-C29 segment of rifamycin S.  109:953-955. 1987
  • Total synthesis of amphotericin-b.  109:2821-2822. 1987
  • Total synthesis of amphoteronolide-b.  109:2208-2210. 1987
  • Enzymatic aldol condensation isomerization as a route to unusual sugar-derivatives.  108:7812-7818. 1986
  • Regioselective phosphoranylation and cyclodehydration of triols with diethoxytriphenylphosphorane.  108:7681-7685. 1986
  • C-C activation of organic small ring compounds by rearrangement of cycloalkylhydridorhodium complexes to rhodacycloalkanes - synthesis of metallacyclobutanes, including one with a tertiary M-C bond, by nucleophilic-addition to p-allyl complexes.  108:7346-7355. 1986
  • Highly chemoselective palladium-catalyzed conjugate reduction of alpha,beta-unsaturated carbonyl-compounds with silicon hydrides and zinc-chloride cocatalyst.  108:7314-7325. 1986
  • Isomerization of the hydridoalkylrhodium complexes formed on oxidative addition of rhodium to alkane C-H bonds - evidence for the intermediacy of h-2-alkane complexes.  108:7332-7346. 1986
  • Bridging of macrocycles to bicycles - new synthetic technology for the construction of cis-fused and trans-fused oxopolycyclic systems.  108:6800-6802. 1986
  • Multiple-quantum-filtered two-dimensional correlated NMR-spectroscopy of proteins.  108:6482-6492. 1986
  • Thermal-reactions of cyclopropenone ketals - application of the cycloaddition reactions of delocalized singlet vinylcarbenes - 3-carbon 1,1-dipoles 1,3-dipoles - an alternative synthesis of deacetamidocolchiceine - formal total synthesis of colchicine.  108:6713-6719. 1986
  • Thermal-reactions of cyclopropenone ketals - key mechanistic features and scope of the cycloaddition reactions of delocalized singlet vinylcarbenes - 3-carbon 1,1-dipoles 1,3-dipoles.  108:6695-6713. 1986
  • Enzyme-catalyzed regioselective deacylation of protected sugars in carbohydrate synthesis.  108:6421-6422. 1986
  • Simplification of two-dimensional h-1-NMR spectra using an x-filter.  108:6162-6167. 1986
  • Convergent functional groups provide a measure of stereoelectronic effects at carboxyl oxygen.  108:6068-6069. 1986
  • Molecular recognition: ionic and aromatic stacking interactions bind complementary functional groups in a molecular cleft.  108:5637-5638. 1986
  • Slow complexation rates of crown ethers: what's taking so long?.  108:5011-5012. 1986
  • Organic-synthesis with enzymes .3. Tbadh-catalyzed reduction of chloro ketones - total synthesis of (+)-(s,s)-(cis-6-methyltetrahydropyran-2-yl)acetic acid - a civet constituent.  108:3474-3480. 1986
  • Stereochemistry of the reactions of substituted allylboronates with chiral aldehydes: factors influencing aldehyde diastereofacial selectivity.  108:3422-3434. 1986
  • Oxygenation of styrene by cytochrome-p-450 model system - a mechanistic study.  108:2588-2594. 1986
  • New synthetic technology for the construction of oxocenes.  108:2468-2469. 1986
  • Stereospecific 1,2-migrations in carbohydrates - stereocontrolled synthesis of alpha-2-deoxyglycoside beta-2-deoxyglycoside.  108:2466-2467. 1986
  • Combined chemical and enzymatic-synthesis of sialyloligosaccharides and characterization by 500-mhz h-1 and c-13 NMR-spectroscopy.  108:2068-2080. 1986
  • Diisopropyl tartrate modified (E)-crotylboronates: highly enantioselective propionate (E)-enolate equivalents.  108:294-296. 1986
  • Thermostable enzymes in organic-synthesis .2. Asymmetric reduction of ketones with alcohol-dehydrogenase from thermoanaerobium-brockii.  108:162-169. 1986
  • Chemo-, regio-, and diastereoselective alkylation via Lewis acid promoted substitutions of sulfones.  108:1098-1100. 1986
  • Diastereoselective and enantioselective aldehyde addition-reactions of 2-allyl-1,3,2-dioxaborolane-4,5-dicarboxylic esters, a useful class of tartrate ester modified allylboronates.  107:8186-8190. 1985
  • Allosteric effects in organic chemistry: binding cooperativity in a model for subunit interactions.  107:7481-7487. 1985
  • Binding forces and catalysis. The use of bipyridyl-metal chelation to enhance reaction rates.  107:7487-7493. 1985
  • Convergent functional groups: synthetic and structural studies.  107:7476-7481. 1985
  • Diethoxytriphenylphosphorane: a mild, regioselective cyclodehydrating reagent for conversion of diols to cyclic ethers. Stereochemistry, synthetic utility, and scope.  107:5210-5219. 1985
  • Enzymatic vs fermentative synthesis - thermostable glucose-dehydrogenase catalyzed regeneration of nad(p)h for use in enzymatic-synthesis.  107:4028-4031. 1985
  • Enzymatic-synthesis of unusual sugars - galactose-oxidase catalyzed stereospecific oxidation of polyols.  107:2997-2999. 1985
  • Epoxidation of olefins by cytochrome-p-450 model compounds - kinetics and stereochemistry of oxygen atom transfer and origin of shape selectivity.  107:2000-2005. 1985
  • Exchange of 2-spin order in nuclear magnetic-resonance - separation of exchange and cross-relaxation processes.  107:6440-6446. 1985
  • Inverse electron demand Diels-Alder reactions of heterocyclic azadienes - formal total synthesis of streptonigrin.  107:5745-5754. 1985
  • Mechanism of oxygen atom transfer from high valent iron porphyrins to olefins - implications to the biological epoxidation of olefins by cytochrome-p-450.  107:4343-4345. 1985
  • Models for ferredoxins: electronic structures of iron-sulfur clusters with one, two, and four iron atoms.  107:3418-3426. 1985
  • Molecular recognition: three-point binding leads to a selective receptor for aromatic amino acids.  107:6738-6739. 1985
  • Polypeptide metal cluster connectivities in metallothionein-2 by novel h-1-cd-113 heteronuclear two-dimensional NMR experiments.  107:6847-6851. 1985
  • Steady-state kinetic-studies of superoxide dismutases - properties of the iron containing protein from escherichia-coli.  107:3295-3304. 1985
  • Stereocontrolled total synthesis of lipoxins-a.  107:7515-7518. 1985
  • Stereospecific synthesis of rhynchosporosides - a family of fungal metabolites causing scald disease in barley and other grasses.  107:5556-5558. 1985
  • Synthetic receptors: size and shape-recognition within a molecular cleft.  107:6736-6738. 1985
  • Total synthesis of elfamycins - aurodox and efrotomycin .1. Strategy and construction of key intermediates.  107:1691-1694. 1985
  • Total synthesis of elfamycins - aurodox and efrotomycin .2. Coupling of key intermediates and completion of the synthesis.  107:1695-1698. 1985
  • Trichothecene metabolism studies: isolation and structure determination of 15-​acetyl-​3α-​(1'β-​D-​glucopyranosiduronyl)​scirpen-​3,​4β,​15-​triol.  107:3354-3355. 1985
  • A general and stereocontrolled total synthesis of leukotriene-b4 and analogs.  106:3548-3551. 1984
  • Crystal-structures of 2 titanium tartrate asymmetric epoxidation catalysts.  106:6430-6431. 1984
  • Effective, thermal 3-carbon + 2-carbon cycloaddition for cyclopentenone formation - formal 1,3-dipolar cycloaddition of cyclopropenone ketals.  106:805-807. 1984
  • Electronic structure, magnetic properties, ESR, and optical spectra for 2-Fe ferredoxin models by LCAO-X alpha valence bond theory.  106:2316-2327. 1984
  • Epoxidations with selective peracids.  106:1170-1171. 1984
  • Practical synthesis of oligosaccharides - partial synthesis of avermectin-b1a.  106:4189-4192. 1984
  • Rapid intramolecular rearrangement of a hydridocyclopropylrhodium complex to a rhodacyclobutane - independent synthesis of the metallacycle by addition of hydride to the central carbon-atom of a cationic rhodium p-allyl complex.  106:7272-7273. 1984
  • Sulfones as chemical chameleons. Cyclization via 1,1-dipole synthons.  106:7260-7261. 1984
  • Synthesis of ergot alkaloids from tryptophan.  106:1813-1819. 1984
  • Total synthesis of (-)-ptilocaulin.  106:721-723. 1984
  • Total synthesis of 5(s),15(s)-dihydroxy-6,13-trans-8,11-cis-eicosatetraenoic acid (5,15-dihete) and 8(s),15(s)-dihydroxy-5,11-cis-9,13-trans-eicosatetraenoic acid (8,15-dihete) - 2 novel metabolites of arachidonic-acid.  106:5734-5736. 1984
  • A mild and general-method for the synthesis of o-glycosides.  105:2430-2434. 1983
  • Allosteric effects: an on-off switch.  105:6668-6670. 1983
  • Allosteric effects: structural and thermodynamic origins of binding in cooperativity in a subunit model.  105:6759-6760. 1983
  • Enzyme-catalyzed organic-synthesis - regeneration of deuterated nicotinamide cofactors for use in large-scale enzymatic-synthesis of deuterated substances.  105:5012-5014. 1983
  • Hydrogen-bond length and h-1-NMR chemical-shifts in proteins.  105:5948-5949. 1983
  • Preparation of a mixture of nucleoside triphosphates from yeast rna - use in enzymatic-synthesis requiring nucleoside triphosphate regeneration and conversion to nucleoside diphosphate sugars.  105:115-117. 1983
  • Resonance raman-spectroscopic evidence for a common 3fe-4s structure among proteins containing 3-iron centers.  105:6671-6678. 1983
  • Sequence-specific double-strand cleavage of DNA by bis(EDTA-distamycin.Fe(II) ) and EDTA-bis(distamycin).Fe(II).  105:7748-7750. 1983
  • Sequential assignments for the h-1 and p-31 atoms in the backbone of oligonucleotides by two-dimensional nuclear magnetic-resonance.  105:1652-1653. 1983
  • The mechanism of fe-edta catalyzed superoxide dismutation.  105:5290-5300. 1983
  • Total synthesis of (+/-)-verrucarol.  105:1058-1060. 1983
  • Carbohydrates in organic-synthesis - synthesis of 16-membered-ring macrolide antibiotics .5. Total synthesis of o-mycinosyltylonolide - synthesis of key intermediates.  104:2027-2029. 1982
  • Carbohydrates in organic-synthesis - synthesis of 16-membered-ring macrolide antibiotics .6. Total synthesis of o-mycinosyltylonolide - coupling of key intermediates and macrocyclization.  104:2030-2031. 1982
  • Design and synthesis of a sequence-specific DNA cleaving molecule. (Distamycin-EDTA)iron(II).  104:6861-6863. 1982
  • Direct studies of 1,1-diazenes. Syntheses, infrared and electronic spectra, and kinetics of the thermal decomposition of N-(2,2,6,6-tetramethylpiperidyl)nitrene and N-(2,2,5,5-tetramethylpyrrolidyl)nitrene.  104:766-773. 1982
  • Enzyme-catalyzed transhydrogenation between nicotinamide cofactors and its application in organic-synthesis.  104:3542-3544. 1982
  • General-method for determining absolute-configurations of acyclic allylic alcohols.  104:3775-3776. 1982
  • Photochemistry of 1,1-diazenes. Direct and sensitized photolyses of N-(2,2,5,5-tetramethylpyrrolidyl)nitrene, dl-N-(2,5-diethyl-2,5-dimethylpyrrolidyl)nitrene, and N-(2,2,6,6-tetramethylpiperidyl)nitrene.  104:6660-6668. 1982
  • Soret-excited resonance raman-spectrum of (carbon monoxy)leghemoglobin - assignment of nu-fe-co.  104:626-627. 1982
  • Stereochemical aspects of the intramolecular Diels-Alder reactions of deca-2,7,9-trienoate esters. 3. Thermal, Lewis acid-catalyzed, and asymmetric cyclizations.  104:2269-2283. 1982
  • Synthesis of saccharides and related polyhydroxylated natural-products .3. Efficient conversion of 2,3-erythro-aldoses to 2,3-threo-aldoses.  104:3515-3516. 1982
  • Synthesis of saccharides and related polyhydroxylated natural-products .4. Alpha-d-c-glycopyranoside and beta-d-c-glycopyranoside (2,6-dialkyl-substituted tetrahydropyrans).  104:6468-6470. 1982
  • The endiandric acid cascade - electrocyclizations in organic-synthesis .1. Stepwise, stereocontrolled total synthesis of endiandric acid-a and acid-b.  104:5555-5557. 1982
  • The endiandric acid cascade - electrocyclizations in organic-synthesis .2. Stepwise, stereocontrolled total synthesis of endiandric acids-c-acid-g.  104:5557-5558. 1982
  • The endiandric acid cascade - electrocyclizations in organic-synthesis .3. Biomimetic approach to endiandric acids-a-acid-g - synthesis of precursors.  104:5558-5560. 1982
  • The endiandric acid cascade - electrocyclizations in organic-synthesis .4. Biomimetic approach to endiandric acids-a-acid-g - total synthesis and thermal studies.  104:5560-5562. 1982
  • The mechanism of specific acylation of the active-site of alpha-chymotrypsin by n-acylimidazoles.  104:3569-3576. 1982
  • Asymmetric epoxidation provides shortest routes to 4 chiral epoxy alcohols which are key intermediates in syntheses of methymycin, erythromycin, leukotriene c-1, and disparlure.  103:464-465. 1981
  • Buildup rates of the nuclear overhauser effect measured by two-dimensional proton magnetic-resonance spectroscopy - implications for studies of protein conformation.  103:3654-3658. 1981
  • Enzyme-catalyzed organic-synthesis - nad(p)h cofactor regeneration by using glucose-6-phosphate and the glucose-6-phosphate-dehydrogenase from leuconostoc-mesenteroides.  103:4890-4899. 1981
  • Enzyme-catalyzed organic-synthesis - nad(p)h regeneration using dihydrogen and the hydrogenase from methanobacterium-thermoautotrophicum.  103:6227-6228. 1981
  • Epoxy alcohol rearrangements - hydroxyl-mediated delivery of lewis acid promoters.  103:462-464. 1981
  • Intramolecular Diels-Alder reactions: the angularly methylated trans-perhydroindan ring system.  103:6696-6704. 1981
  • Kinetic resolution of racemic allylic alcohols by enantioselective epoxidation - a route to substances of absolute enantiomeric purity.  103:6237-6240. 1981
  • Magnetic studies and the crystal and molecular-structure of enh2 v(hedta-h) 2.2h2o - a novel di-mu-alcoxy-bridged dimer of 7-coordinate v(iii).  103:5511-5517. 1981
  • Organoselenium-based synthesis of oxygen-containing prostacyclins.  103:3480-3485. 1981
  • Organoselenium-based synthesis of sulfur-containing prostacyclins.  103:3486-3497. 1981
  • Photochemistry of a 1,1-diazene, N-(2,2,5,5-tetramethylpyrrolidinyl)nitrene.  103:1563-1564. 1981
  • Studies on the total synthesis of chlorothricolide: stereochemical aspects of the intramolecular Diels-Alder reactions of methyl undeca-2,8,10-trienoates.  103:5200-5211. 1981
  • Synthesis of (5z)-6,9-thiaprostacyclins and (5e)-6,9-thiaprostacyclins.  103:3472-3480. 1981
  • Synthesis of 16-membered-ring macrolide antibiotics .3. Carbomycin-b and leucomycin-a3 - retrosynthetic studies.  103:1222-1224. 1981
  • Synthesis of 16-membered-ring marcolide antibiotics .4. Carbomycin-b and leucomycin-a3 - total synthesis of cyclic key intermediate.  103:1224-1226. 1981
  • Total synthesis of ionophore antibiotic x-14547a .1. Enantioselective synthesis of the tetrahydropyran and tetrahydroindan building-blocks.  103:6967-6969. 1981
  • Total synthesis of ionophore antibiotic x-14547a .2. Coupling of the tetrahydropyran and tetrahydroindan systems and construction of the butadienyl and ketopyrrole moieties.  103:6969-6971. 1981
  • Allosteric effects. Remote control of ion transport selectivity.  102:4853-4854. 1980
  • Asymmetric induction in the reaction of osmium-tetroxide with olefins.  102:4263-4265. 1980
  • Carbocyclic thromboxane-a2.  102:1404-1409. 1980
  • Does substrate rather than protein provide the catalyst for alpha-proton abstraction in aldolase.  102:3923-3927. 1980
  • Electronic structure of 2-Fe ferredoxin models by X alpha valence bond theory.  102:4279-4282. 1980
  • Olefin epoxidation with alpha-substituted hydroperoxides.  102:5602-5605. 1980
  • On binding in subunit systems.  102:7398-7400. 1980
  • Phenylselenoetherification - a highly efficient cyclization process for the synthesis of o-heterocycles and s-heterocycles.  102:3784-3793. 1980
  • Practical enzymatic syntheses of ribulose 1,5-bisphosphate and ribose 5-phosphate.  102:7938-7939. 1980
  • Synthesis and direct spectroscopic observation of N-(2,2,5,5-tetramethylpyrrolidyl)nitrene: comparison of 5-membered and 6-membered cyclic 1,1-dialkyldiazenes.  102:878-880. 1980
  • The first practical method for asymmetric epoxidation.  102:5974-5976. 1980
  • Total synthesis of (+/-)-dendrobine.  102:1390-1404. 1980
  • Total synthesis of (+/-)-zoapatanol.  102:6611-6612. 1980
  • Total synthesis of rugulovasines.  102:5426-5427. 1980
  • 6,9-pyridazaprostacyclin and derivatives: the first "aromatic" prostacyclins.  101:766-768. 1979
  • Allosteric effects in organic chemistry. Site-specific binding.  101:4333-4337. 1979
  • On the rate of site-site interactions in functionalized polystyrenes.  101:737. 1979
  • Phenylselenolactonization and phenylsulfenolactonization - 2 highly efficient and synthetically useful cyclization procedures.  101:3884-3892. 1979
  • Selective naked-cluster cryophotochemistry and SCF-X alpha-SW calculations for Cu2 and Ag2.  101:3504-3511. 1979
  • Chemistry of singlet oxygen. 29. A specific three-phase "Kautsky test" for singlet oxygen.  100:7770-7771. 1978
  • Dynamics of tautomerization of formycin.  100:3957-3958. 1978
  • On binding to transition states and ground states: remote catalysis.  100:4315-4316. 1978
  • Organoselenium-induced ring closures - sulfur-containing prostacyclins - stereoselective synthesis of cyclic alpha,beta-unsaturated sulfoxides, sulfones, and sulfides and synthesis of 6,9-sulfoxa-5(e)-and-5(z)-prostacyclin, 6,9-sulfo-5(e)-and-5(z)-prostacyclin, 6,9-sulfo-6alpha-and-6beta-4(e)-isoprostacyclin, and 6,9-thiaprostacycline.  100:2567-2570. 1978
  • Osmium-catalyzed vicinal oxyamination of olefins by n-chloro-n-argentocarbamates.  100:3596-3598. 1978
  • Steric steering with supported palladium catalysts.  100:7779-7781. 1978
  • The first d0 metallooxaziridines. Amination of olefins.  100:7061-7063. 1978
  • The three-phase test: intermediates in phosphate transfer reactions.  100:8113-8117. 1978
  • Total synthesis of (+/-)-dendrobine.  100:3599-3601. 1978
  • Total synthesis of erythromycins .3. Stereoselective routes to intermediates corresponding to c(1) to c(9) and c(10) to c(13) fragments of erythronolide-b.  100:4618-4620. 1978
  • Total synthesis of erythromycins .4. Total synthesis of erythronolide-b.  100:4620-4622. 1978
  • Transient proton-proton overhauser effects in horse ferrocytochrome-c.  100:7094-7096. 1978
  • 6,9-thiaprostacyclin. A stable and biologically potent analogue of prostacyclin (PGI2).  99:7736-7738. 1977
  • Allylic oxidation of olefins by catalytic and stoichiometric selenium dioxide with tert-butyl hydroperoxide.  99:5526-5528. 1977
  • Catalysis of superoxide dismutation by iron-ethylenediaminetetraacetic acid complexes - mechanism of reaction and evidence for direct formation of an iron(iii)-ethylenediaminetetraacetic acid peroxo complex from reaction of superoxide with "iron(ii)-ethylenediaminetetraacetic acid.  99:5220-5222. 1977
  • Chiral hydroxamic acids as ligands in vanadium catalyzed asymmetric epoxidation of allylic alcohols by tert-butyl hydroperoxide.  99:1990-1992. 1977
  • Chromyl chloride oxidations of olefins - possible role of organometallic intermediates in oxidations of olefins by oxo transition-metal species.  99:3120-3128. 1977
  • Organic chemistry on the solid phase. Site-site interactions on functionalized polystyrene.  99:625-626. 1977
  • Phenylselenolactonization - extremely mild and synthetically useful cyclization process.  99:3185-3187. 1977
  • Synthesis of dioxobis(tert-alkylimido)osmium(viii) and oxotris(tert-alkylimido)osmium(viii) complexes - stereospecific vicinal diamination of olefins.  99:3420-3426. 1977
  • Allylic amination of olefins and acetylenes by imido selenium-compounds.  98:269-271. 1976
  • Osmium catalyzed vicinal hydroxylation of olefins by tert-butyl hydroperoxide under alkaline conditions.  98:1986-1987. 1976
  • Selenium dioxide oxidation of ketones and aldehydes - evidence for intermediacy of beta-ketoseleninic acids.  98:300-301. 1976
  • Kinetics and equilibria of reaction of pyridoxal 5'-phosphate with ethylenediamine to form schiff-bases and cyclic geminal diamines - evidence for kinetically competent geminal diamine intermediates in transimination sequences.  97:6530-6539. 1975
  • New probes for the study of acylation reactions.  97:4407-4408. 1975
  • Oxidation of alcohols to aldehydes by reagents derived from chromyl chloride.  97:5927-5928. 1975
  • The three phase test for reaction intermediates. Evidence for monomeric metaphosphate.  97:3221-3222. 1975
  • The three-phase test for reaction intermediates. Metaphosphates.  97:1591-1592. 1975
  • The three-phase test for reaction intermediates. Nucleophilic catalysis and elimination reactions.  97:454-455. 1975
  • Three-phase test. Detection of free cyclobutadiene.  97:3453-3456. 1975
  • Efficient and mild lactonization method for synthesis of macrolides.  96:5614-5616. 1974
  • Intermolecular proton-transfer reaction between base and phosphate moieties of mononucleotides in solution.  96:2609-2611. 1974
  • Mechanism of the carbodiimide reaction. II. Peptide synthesis on the solid phase.  96:1606-1607. 1974
  • The three-phase test for reactive intermediates. Cyclobutadiene.  96:7112-7114. 1974
  • An improved method for the study of reaction intermediates. The mechanism of peptide synthesis mediated by carbodiimides.  95:4052-4053. 1973
  • Diastereomeric monocyclic diallenes. Synthesis and properties of the diastereomeric 3,4,9,10-cyclododecatetraene-1,7-diones and 3,4,10,11-cyclotetradecatetraene-1,8-diones.  95:4582-4592. 1973
  • Electrophilic and nucleophilic organoselenium reagents. New routes to alpha, beta-unsaturated carbonyl compounds.  95:6137-6139. 1973
  • High stereo- and regioselectivities in the transition metal catalyzed epoxidations of olefinic alcohols by tert-butyl hydroperoxide.  95:6136-6137. 1973
  • Reorientational correlation-functions obtained from Raman line shapes.  95:1391-1398. 1973
  • Selenium dioxide oxidations of olefins - trapping of allylic seleninic acid intermediate as a seleninolactone.  95:7917-7919. 1973
  • Lower valent tungsten halides. New class of reagents for deoxygenation of organic molecules.  94:6538-6540. 1972
  • Mechanism of epoxidation of olefins by covalent peroxides of molybdenum(vi).  94:295-296. 1972
  • Selenium dioxide oxidation of olefins. Evidence for intermediacy of allylseleninic acids.  94:7154-7155. 1972
  • Permanganate in acetic anhydride. Alpha-diketones directly from olefins.  93:3303-3304. 1971
  • D,l-malabaricanediol. The first cyclic natural product derived from squalene in a nonenzymic process.  92:6999-7001. 1970
  • Magnetic resonance and mass spectrum of pi-cyclopentadienyl-pi-cycloheptatrienylvanadium. Mass spectral rearrangement to bis(benzene)vanadium.  92:5100-5104. 1970
  • Peptide racemization mechanism. A kinetic isotope effect as a means of distinguishing enolization from oxazolone formation.  92:5792-5793. 1970
  • Racemization during peptide couplings using the mixed anhydride, N-hydroxysuccinimide ester, 8-hydroxyquinoline ester, and acyl azide methods.  92:4756-4757. 1970
  • Mechanism of the titanium-promoted deoxygenative coupling of allyl and benzyl alcohols to hydrocarbons.  91:1552-1554. 1969
  • Terpene terminal epoxides. Skeletal rearrangement accompanying bicyclization of squalene 2,3-oxide.  91:1848-1849. 1969
  • Enzymic cyclization of 15-norsqualene 2,3-oxide.  90:3284-3286. 1968
  • One-step synthesis of 1,5-dienes involving reductive coupling of allyl alcohols.  90:209-210. 1968
  • An investigation of water-urea and water-urea-polyethylene glycol interactions.  89:442-446. 1967
  • Biological activities of some terminally modified squalene and squalene 2,3-oxide analogs.  89:3920-3922. 1967
  • Dipole moments in relation to configuration of polypeptide chains.  89:6807-6813. 1967
  • Enzymic cyclization of trans,trans,trans-18,19-dehydrosqualene 2,3-oxide.  89:7150-7151. 1967
  • Equilibrium measurements of the binding of cytidine 3'-phosphate to ribonuclease.  87:4665-4669. 1965
  • Purification and characterization of sheep prolactin.  83:3717-3719. 1961
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Identity

International Standard Serial Number (ISSN)

  • 0002-7863

Electronic International Standard Serial Number (EISSN)

  • 1520-5126

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