Journal of the American Chemical Society
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Overview
articles
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11-step total synthesis of teleocidins B-1-6-4.
141:1494-1497.
2019
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A designed small molecule inhibitor of a non-coding RNA sensitizes HER2 negative cancers to herceptin.
141:2960-2974.
2019
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A radical approach to anionic chemistry: synthesis of ketones, alcohols, and amines.
141:6726-6739.
2019
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Allyl-nickel catalysis enables carbonyl dehydrogenation and oxidative cycloalkenylation of ketones.
141:5669-5674.
2019
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An efficient modular one-pot synthesis of heparin-based anticoagulant idraparinux.
141:10309-10314.
2019
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Analysis of protein-protein interaction in a single live cell by using a FRET system based on genetic code expansion technology.
141:4273-4281.
2019
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Asymmetric total synthesis of arcutinidine, arcutinine, and arcutine.
141:13718-13723.
2019
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Characterization and crystal structure of a nonheme diiron monooxygenase involved in platensimycin and platencin biosynthesis.
141:12406-12412.
2019
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Chemical interventions for the opioid crisis: key advances and remaining challenges.
141:1798-1806.
2019
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Concise total synthesis of herqulines B and C.
141:29-32.
2019
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Controlled cationic polymerization: single-component initiation under ambient conditions.
141:10605-10609.
2019
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Convergent total synthesis of principinol D, a rearranged kaurane diterpenoid.
141:8088-8092.
2019
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Cryptic and stereospecific hydroxylation, oxidation, and reduction in platensimycin and platencin biosynthesis.
141:4043-4050.
2019
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Development of a terpene feedstock-based oxidative synthetic approach to the illicium sesquiterpenes.
141:3083-3099.
2019
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Direct carbon isotope exchange through decarboxylative carboxylation.
141:774-779.
2019
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Electrochemically driven, Ni-catalyzed aryl amination: scope, mechanism, and applications.
141:6392-6402.
2019
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Enantioselective synthesis of azamerone.
141:2867-2871.
2019
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Expanding reactivity in DNA-encoded library synthesis via reversible binding of DNA to an inert quaternary ammonium support.
141:9998-10006.
2019
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General synthetic approach for the Laurencia family of natural products empowered by a potentially biomimetic ring expansion.
141:7776-7788.
2019
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Hydroalkylation of olefins to form quaternary carbons.
141:7709-7714.
2019
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Impact of stereo- and regiochemistry on energetic materials.
141:12531-12535.
2019
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Monoclonal antibodies for combating synthetic opioid intoxication.
141:10489-10503.
2019
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Natural products in the "marketplace": Interfacing synthesis and biology.
141:3332-3346.
2019
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Nickel-catalyzed enantioselective hydroarylation and hydroalkenylation of styrenes.
141:3395-3399.
2019
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Oligosaccharide synthesis and translational innovation.
141:3735-3754.
2019
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Optimization of replication, transcription, and translation in a semi-synthetic organism.
141:10644-10653.
2019
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Rh(III)-catalyzed meta-C-H alkenylation with alkynes.
141:76-79.
2019
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Sequential functionalization of meta-C-H and ipso-C-O bonds of phenols.
141:1903-1907.
2019
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Synthesis of sialidase-resistant oligosaccharide and antibody glycoform containing α2,6-linked 3Fax-Neu5Ac.
141:6484-6488.
2019
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Targeting RNA with small molecules to capture opportunities at the intersection of chemistry, biology, and medicine.
141:6776-6790.
2019
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The total synthesis of chalcitrin.
141:4515-4520.
2019
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Total synthesis of (+)-arborisidine.
141:7715-7720.
2019
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Total synthesis of (+)-granatumine A and related bislactone limonoid alkaloids via a pyran to pyridine interconversion.
141:9191-9196.
2019
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Total synthesis of paspaline A and emindole PB enabled by computational augmentation of a transform-guided retrosynthetic strategy.
141:1479-1483.
2019
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"Inverse drug discovery" strategy to identify proteins that are targeted by latent electrophiles as exemplified by aryl fluorosulfates.
140:200-210.
2018
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A tool for the import of natural and unnatural nucleoside triphosphates into bacteria.
140:1447-1454.
2018
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An oxetane-based polyketide surrogate To probe substrate binding in a polyketide synthase.
140:4961-4964.
2018
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Analyte-driven disassembly and turn-on fluorescent sensing in competitive biological media.
140:3500-3504.
2018
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Bacterial genome containing chimeric DNA-RNA sequences.
140:11464-11473.
2018
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Branch-selective addition of unactivated olefins into imines and aldehydes.
140:16976-16981.
2018
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C(alkenyl)-H activation via six-membered palladacycles: catalytic 1,3-diene synthesis.
140:5805-5813.
2018
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Catalytic carbo- and aminoboration of alkenyl carbonyl compounds via five- and six-membered palladacycles.
140:3223-3227.
2018
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Catalytic regio- and enantioselective haloazidation of allylic alcohols.
140:15646-15650.
2018
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Catalytically active single-chain polymeric nanoparticles: exploring their functions in complex biological media.
140:3423-3433.
2018
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Controlled formation and binding selectivity of discrete oligo(methyl methacrylate) stereocomplexes.
140:1945-1951.
2018
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Copper-catalyzed electrochemical C-H amination of arenes with secondary amines.
140:11487-11494.
2018
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Copper-catalyzed vinylogous aerobic oxidation of unsaturated compounds with air.
140:5300-5310.
2018
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Cytochrome P450-catalyzed hydroxylation initiating ether formation in platensimycin biosynthesis.
140:12349-12353.
2018
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Design of a DNA-programmed plasminogen activator.
140:15516-15524.
2018
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Diprovocims: A new and exceptionally potent class of toll-like receptor agonists.
140:14440-14454.
2018
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Direct access to versatile electrophiles via catalytic oxidative cyanation of alkenes.
140:8069-8073.
2018
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Discovery and characterization of 1-aminocyclopropane-1-carboxylic acid synthase of bacterial origin.
140:16957-16961.
2018
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Divergent synthesis of pyrone diterpenes via radical cross coupling.
140:7462-7465.
2018
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Enantioselective synthesis of pyrroloindolines via noncovalent stabilization of indole radical cations and applications to the synthesis of alkaloid natural products.
140:3394-3402.
2018
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Enantioselective γ-C(sp3)-H activation of alkyl amines via Pd(II)/Pd(0) catalysis.
140:5322-5325.
2018
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Engineering improved antiphosphotyrosine antibodies based on an immunoconvergent binding motif.
140:16615-16624.
2018
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Enhancing protein stability with genetically encoded noncanonical amino acids.
140:15997-16000.
2018
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Extrinsic tryptophans as NMR probes of allosteric coupling in membrane proteins: application to the A2A adenosine receptor.
140:8228-8235.
2018
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Functional replacement of histidine in proteins to generate noncanonical amino acid dependent organisms.
140:3829-3832.
2018
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Iron-nickel dual-catalysis: a new engine for olefin functionalization and the formation of quaternary centers.
140:11317-11324.
2018
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Ligand-enabled β-C(sp3)-H olefination of free carboxylic acids.
140:10363-10367.
2018
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Ligand-enabled γ-C(sp3)-H activation of ketones.
140:3564-3568.
2018
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Macrocyclization of interferon-poly(α-amino acid) conjugates significantly improves the tumor retention, penetration, and antitumor efficacy.
140:1170-1178.
2018
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Mechanism of the Ullmann biaryl ether synthesis catalyzed by complexes of anionic ligands: Evidence for the reaction of iodoarenes with ligated anionic Cu-I intermediates.
140:793-806.
2018
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Mechanistic interrogation of Co/Ni-dual catalyzed hydroarylation.
140:12056-12068.
2018
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Mechanistic investigation and multiplexing of liposome-assisted metabolic glycan labeling.
140:3592-3602.
2018
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Mixed explicit-implicit solvation approach for modeling of alkane complexation in water-soluble self-assembled capsules.
140:12527-12537.
2018
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Modulation of fluorescent protein chromophores to detect protein aggregation with turn-on fluorescence.
140:7381-7384.
2018
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Natural product total synthesis: as exciting as ever and here to stay.
140:4751-4755.
2018
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Ni-catalyzed regioselective alkylarylation of vinylarenes via C(sp3)–C(sp3)/C(sp3)–C(sp2) bond formation and mechanistic studies.
140:9801-9805.
2018
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Ni-catalyzed regioselective β,δ-diarylation of unactivated olefins in ketimines via ligand-enabled contraction of transient nickellacycles: rapid access to remotely diarylated ketones.
140:7782-7786.
2018
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Nickel-catalyzed 1,2-diarylation of simple alkenyl amides.
140:17878-17883.
2018
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Nickel-catalyzed dearomative trans-1,2-carboamination.
140:4503-4507.
2018
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Osmolytes and protein-protein interactions.
140:7441-7444.
2018
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Overcoming the limitations of γ, and δ-C-H arylation of amines through ligand development.
140:17884-17894.
2018
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Pd(II)-catalyzed enantioselective C(sp(3))-H arylation of free carboxylic acids.
140:6545-6549.
2018
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Progress toward a semi-synthetic organism with an unrestricted expanded genetic alphabet.
140:16115-16123.
2018
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Promysalin elicits species-selective inhibition of pseudomonas aeruginosa by targeting succinate dehydrogenase.
140:1774-1782.
2018
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Remote C-H hydroxylation by an α-ketoglutarate-dependent dioxygenase enables efficient chemoenzymatic synthesis of manzacidin C and proline analogs.
140:1165-1169.
2018
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Reprograming the replisome of a semisynthetic organism for the expansion of the genetic alphabet.
140:758-765.
2018
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Rhodium-catalyzed B-H bond insertion reactions of unstabilized diazo compounds generated in situ from tosylhydrazones.
140:10663-10668.
2018
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Scalable access to arylomycins via C-H functionalization logic.
140:2072-2075.
2018
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Slow dynamics of tryptophan-water networks in proteins.
140:675-682.
2018
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Small molecule targeted recruitment of a nuclease to RNA.
140:6741-6744.
2018
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SuFEx click chemistry enabled late-stage drug functionalization.
140:2919-2925.
2018
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Synergistic bimetallic Ni/Ag and Ni/Cu catalysis for regioselective γ,δ-diarylation of alkenyl ketimines: addressing β-H elimination by in situ generation of cationic Ni(II) catalysts.
140:15586-15590.
2018
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Synthesis and mechanochemical activation of ladderene-norbornene block copolymers.
140:12388-12391.
2018
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Total Synthesis of Septedine and 7-Deoxyseptedine.
140:9025-9029.
2018
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Total synthesis of (-)-xylogranatopyridine B via a palladium-catalyzed oxidative stannylation of enones.
140:2062-2066.
2018
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Total synthesis of aplysiasecosterol A.
140:9211-9218.
2018
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Total synthesis of hybridaphniphylline B.
140:4227-4231.
2018
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Total synthesis of the caged indole alkaloid arboridinine enabled by aza-Prins and metal-mediated cyclizations.
140:919-925.
2018
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Total synthesis, biological evaluation, and target identification of rare Abies sesquiterpenoids.
140:17465-17473.
2018
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Unprecedented role of hybrid N-glycans as ligands for HIV-1 broadly neutralizing antibodies.
140:5202-5210.
2018
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A role for Pd(IV) in catalytic enantioselective C-H functionalization with monoprotected amino acid ligands under mild conditions.
139:9238-9245.
2017
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Antimicrobials inspired by nonribosomal peptide synthetase gene clusters.
139:1404-1407.
2017
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Assembly of the limonoid architecture by a divergent approach: total synthesis of (±)-andirolide N via (±)-8α-hydroxycarapin.
139:631-634.
2017
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CD22 ligands on a natural N-glycan scaffold efficiently deliver toxins to B-lymphoma cells.
139:12450-12458.
2017
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Catalytic B-H bond insertion reactions using alkynes as carbene precursors.
139:3784-3789.
2017
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Catalytic intermolecular carboamination of unactivated alkenes via directed aminopalladation.
139:11261-11270.
2017
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Chemical stabilization of unnatural nucleotide triphosphates for the in vivo expansion of the genetic alphabet.
139:2464-2467.
2017
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Chemically controlled epigenome editing through an inducible dCas9 system.
139:11337-11340.
2017
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Co-assembly of peptide amphiphiles and lipids into supramolecular nanostructures driven by anion-π interactions.
139:7823-7830.
2017
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Concurrent modulation of quantum dot photoluminescence using a combination of charge transfer and Forster resonance energy transfer: competitive quenching and multiplexed biosensing modality.
139:363-372.
2017
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Copper-catalyzed dicarbofunctionalization of unactivated olefins by tandem cyclization/cross-coupling.
139:5700-5703.
2017
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Covalent capture of aligned self-assembling nanofibers.
139:8044-8050.
2017
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Covalent modulators of the vacuolar ATPase.
139:639-642.
2017
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Critical analysis of rate constants and turnover frequency in nucleic acid-templated reactions: reaching terminal velocity.
139:1444-1447.
2017
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Crystal-phase transitions and photocatalysis in supramolecular scaffolds.
139:6120-6127.
2017
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Cu(II)-catalyzed ortho-selective aminomethylation of phenols.
139:12390-12393.
2017
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Cyanine conformational restraint in the far-red range.
139:12406-12409.
2017
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Defining the structural basis for allosteric product release from E. coli dihydrofolate reductase using NMR relaxation dispersion.
139:11233-11240.
2017
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Design of benzoxathiazin-3-one 1,1-dioxides as a new class of irreversible serine hydrolase inhibitors: Discovery of a uniquely selective PNPLA4 inhibitor.
139:7052-7061.
2017
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Development of a clinically viable heroin vaccine.
139:8601-8611.
2017
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Diverse ortho-C(sp(2))-H functionalization of benzaldehydes using transient directing groups.
139:888-896.
2017
-
Diverse redoxome reactivity profiles of carbon nucleophiles.
139:5588-5595.
2017
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Dynamic ligand exchange as a mechanistic probe in Pd-catalyzed enantioselective C-H functionalization reactions using monoprotected amino acid ligands.
139:18500-18503.
2017
-
Efficient liver targeting by polyvalent display of a compact ligand for the asialoglycoprotein receptor.
139:3528-3536.
2017
-
Enantioselective chemical syntheses of the furanosteroids (-)-viridin and (-)-viridiol.
139:6819-6822.
2017
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Enantiospecific solvolytic functionalization of bromochlorides.
139:13562-13569.
2017
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Enantiospecific total synthesis of the highly strained (-)-presilphiperfolan-8-ol via a Pd-catalyzed tandem cyclization.
139:5007-5010.
2017
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Engineering bifunctional antibodies with constant region fusion architectures.
139:18607-18615.
2017
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Experimental and computational development of a conformationally flexible template for the meta-C-H functionalization of benzoic acids.
139:10702-10714.
2017
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Fe-catalyzed C-C bond construction from olefins via radicals.
139:2484-2503.
2017
-
Fluorescence turn-on sensing of DNA duplex formation by a tricyclic cytidine analogue.
139:1372-1375.
2017
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Frustrated Lewis acid/Brønsted base catalysts for direct enantioselective α-amination of carbonyl compounds.
139:95-98.
2017
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Generation of an orthogonal protein-protein interface with a noncanonical amino acid.
139:5728-5731.
2017
-
Genetically encoded fluorescent probe for detecting sirtuins in living cells.
139:12350-12353.
2017
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Glutamine amide flip elicits long distance allosteric responses in the LOV protein vivid.
139:2972-2980.
2017
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Heterogeneous-backbone foldamer mimics of zinc finger tertiary structure.
139:7931-7938.
2017
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Highly versatile β-C(sp3)-H iodination of ketones using a practical auxiliary.
139:12394-12397.
2017
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In vivo structure-activity relationships and optimization of an unnatural base pair for replication in a semi-synthetic organism.
139:11427-11433.
2017
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Investigation of trimethyllysine binding by the HP1 chromodomain via unnatural amino acid mutagenesis.
139:17253-17256.
2017
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Isolable and readily handled halophosphonium pre-reagents for hydro- and deuteriohalogenation.
139:6329-6337.
2017
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Isomer-specific hydrogen bonding as a design principle for bidirectionally quantitative and redshifted hemithioindigo photoswitches.
139:10956-10959.
2017
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Ligand-enabled Pd(II)-catalyzed bromination and iodination of C(sp3)-H bonds.
139:5724-5727.
2017
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Ligand-enabled meta-selective C-H arylation of nosyl-protected phenethylamines, benzylamines, and 2-aryl anilines.
139:417-425.
2017
-
Mechanistic insight into the photocontrolled cationic polymerization of vinyl ethers.
139:15530-15538.
2017
-
Metal ions effectively ablate the action of Botulinum neurotoxin A.
139:7264-7272.
2017
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Modular, scalable synthesis of group A streptogramin antibiotics.
139:13304-13307.
2017
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Ni-catalyzed regioselective 1,2-dicarbofunctionalization of olefins by intercepting Heck intermediates as imine-stabilized transient metallacycles.
139:10653-10656.
2017
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Nickel-catalyzed β,γ-dicarbofunctionalization of alkenyl carbonyl compounds via conjunctive cross-coupling.
139:10657-10660.
2017
-
Palladium(II)-catalyzed directed anti-hydrochlorination of unactivated alkynes with HCl.
139:5183-5193.
2017
-
Palladium-catalyzed C(sp(3))-H oxygenation via electrochemical oxidation.
139:3293-3298.
2017
-
Palladium-catalyzed dearomative syn-1,4-carboamination.
139:17787-17790.
2017
-
Pd(II)-catalyzed enantioselective C(sp(3))-H borylation.
139:3344-3347.
2017
-
Peptide macrocyclization inspired by non-ribosomal imine natural products.
139:5233-5241.
2017
-
Photocontrolled interconversion of cationic and radical polymerizations.
139:10665-10668.
2017
-
Polymerase chain transcription: exponential synthesis of RNA and modified RNA.
139:9949-9954.
2017
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Potassium tert-butoxide-catalyzed dehydrogenative C-H silylation of heteroaromatics: A combined experimental and computational mechanistic study.
139:6867-6879.
2017
-
Programmable assembly of peptide amphiphile via noncovalent-to-covalent bond conversion.
139:8995-9000.
2017
-
Quantum chemical modeling of cycloaddition reaction in a self-assembled capsule.
139:15494-15503.
2017
-
Recombinant macrocyclic lanthipeptides incorporating non-canonical amino acids.
139:11646-11649.
2017
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Regulating miRNA-21 biogenesis by bifunctional small molecules.
139:4987-4990.
2017
-
Residues comprising the enhanced aromatic sequon influence protein N-glycosylation efficiency.
139:12947-12955.
2017
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Rh(III)-catalyzed meta-C-H olefination directed by a nitrile template.
139:2200-2203.
2017
-
Scalable, electrochemical oxidation of unactivated C-H bonds.
139:7448-7451.
2017
-
Selection of 2'-fluoro-modified aptamers with optimized properties.
139:2892-2895.
2017
-
Small molecule inhibition of microRNA-210 reprograms an oncogenic hypoxic circuit.
139:3446-3455.
2017
-
Small molecule recognition triggers secondary and tertiary interactions in DNA folding and hammerhead ribozyme catalysis.
139:9815-9818.
2017
-
Stereochemistry of endogenous palmitic acid ester of 9-hydroxystearic acid and relevance of absolute configuration to regulation.
139:4943-4947.
2017
-
Stereocontrolled synthesis of kalihinol C.
139:3647-3650.
2017
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Stolonidiol: Synthesis, target identification, and mechanism for choline acetyltransferase activation.
139:5865-5869.
2017
-
Strain-release heteroatom functionalization: Development, scope, and stereospecificity.
139:3209-3226.
2017
-
Strained cyclic disulfides enable cellular uptake by reacting with the transferrin receptor.
139:231-238.
2017
-
Structure-activity relationship and molecular mechanics reveal the importance of ring entropy in the biosynthesis and activity of a natural product.
139:2541-2544.
2017
-
Supramolecular "Trojan Horse" for nuclear delivery of dual anticancer drugs.
139:2876-2879.
2017
-
Supramolecular metal-coordination polymers, nets, and frameworks from synthetic coiled-coil peptides.
139:2212-2215.
2017
-
Synthesis of (+)-pancratistatins via catalytic desymmetrization of benzene.
139:15656-15659.
2017
-
Synthesis of (-)-11-O-debenzoyltashironin: neurotrophic sesquiterpenes cause hyperexcitation.
139:9637-9644.
2017
-
Synthesis of Z- or E-trisubstituted allylic alcohols and ethers by kinetically controlled cross-metathesis with a Ru catechothiolate complex.
139:15640-15643.
2017
-
The origins of dramatic differences in five-membered vs six-membered chelation of Pd(II) on efficiency of C(sp3)-H bond activation.
139:8514-8521.
2017
-
Total syntheses of (-)-majucin and (-)-jiadifenoxolane A, complex majucin-type illicium sesquiterpenes.
139:17783-17786.
2017
-
Total syntheses of scaparvins B, C, and D enabled by a Key C-H functionalization.
139:18428-18431.
2017
-
Total synthesis and stereochemical assignment of delavatine A: Rh-catalyzed asymmetric hydrogenation of indene-type tetrasubstituted olefins and kinetic resolution through Pd catalyzed triflamide-directed C-H olefination.
139:5558-5567.
2017
-
Total synthesis of (±)-berkeleyone A.
139:1790-1793.
2017
-
Total synthesis of longeracinphyllin A.
139:14893-14896.
2017
-
Tridentate directing groups stabilize 6-membered palladacycles in catalytic alkene hydrofunctionalization.
139:15576-15579.
2017
-
Versatile alkylation of (hetero)aryl iodides with ketones via β-C(sp3)-H activation.
139:16080-16083.
2017
-
Water dynamics from the surface to the interior of a supramolecular nanostructure.
139:8915-8921.
2017
-
11-step total synthesis of (-)-maoecrystal V.
138:9425-9428.
2016
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11-step total synthesis of araiosamines.
138:14234-14237.
2016
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11-step total synthesis of pallambins C and D.
138:7536-7539.
2016
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A carbohydrate-derived splice modulator.
138:5063-5068.
2016
-
A versatile and scalable strategy to discrete oligomers.
138:6306-6310.
2016
-
Activation of cell-penetrating peptides with Ionpair-π interactions and fluorophiles.
138:11264-11271.
2016
-
Amide α,β-dehydrogenation using allyl-palladium catalysis and a hindered monodentate anilide.
138:1166-1169.
2016
-
An evolved orthogonal enzyme/cofactor pair.
138:12451-12458.
2016
-
Analysis of Loops that Mediate Protein-Protein Interactions and Translation into Submicromolar Inhibitors.
138:12876-12884.
2016
-
Annulative methods enable a total synthesis of the complex meroterpene berkeleyone A.
138:14868-14871.
2016
-
Arylfluorosulfates inactivate intracellular lipid binding protein(s) through chemoselective SuFEx reaction with a binding site Tyr residue.
138:7353-7364.
2016
-
Asymmetric total syntheses of aspidodasycarpine, lonicerine, and the proposed structure of lanciferine.
138:3982-3985.
2016
-
Biosynthetic origin of the ether ring in platensimycin.
138:16711-16721.
2016
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Branch-selective hydroarylation: iodoarene-olefin cross-coupling.
138:12779-12782.
2016
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Capturing unknown substrates via in situ formation of tightly bound bisubstrate adducts: S-adenosyl-vinthionine as a functional probe for AdoMet-dependent methyltransferases.
138:2877-2880.
2016
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Catalysis of heterocyclic azadiene cycloaddition reactions by solvent hydrogen bonding: concise total synthesis of methoxatin.
138:12408-12413.
2016
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Catalytic enantioselective dihalogenation and the selective synthesis of (-)-deschloromytilipin A and (-)-danicalipin A.
138:5150-5158.
2016
-
Catalytic, regioselective hydrocarbofunctionalization of unactivated alkenes with diverse C-H nucleophiles.
138:14705-14712.
2016
-
Cationic polymerization of vinyl ethers controlled by visible light.
138:15535-15538.
2016
-
Cavitands as chaperones for monofunctional and ring-forming reactions in water.
138:7512-7515.
2016
-
Cellular protection of SNAP-25 against botulinum neurotoxin/A: inhibition of thioredoxin reductase through a suicide substrate mechanism.
138:5568-5575.
2016
-
Chemical proteomic profiling of human methyltransferases.
138:13335-13343.
2016
-
Chemical synthesis and self-assembly of a ladderane phospholipid.
138:15845-15848.
2016
-
Chemical tools to monitor and manipulate adaptive immune responses.
138:6076-6094.
2016
-
Cucurbit 7 uril-tetramethylrhodamine conjugate for direct sensing and cellular imaging.
138:16549-16552.
2016
-
Directed, regiocontrolled hydroamination of unactivated alkenes via protodepalladation.
138:5805-5808.
2016
-
Discovery of enzymatic targets of transcriptional activators via in vivo covalent chemical capture.
138:12629-12635.
2016
-
Discovery of pyrophosphate diesters as tunable, soluble, and bioorthogonal linkers for site-specific antibody-drug conjugates.
138:1430-1445.
2016
-
Diverted total synthesis of promysalin analogs demonstrates that an iron-binding motif is responsible for its narrow-spectrum antibacterial activity.
138:5833-5836.
2016
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Evolutionary gain of alanine mischarging to noncognate tRNAs with a G4:U69 base pair.
138:12948-12955.
2016
-
Extended-charge-transfer excitons in crystalline supramolecular photocatalytic scaffolds.
138:11762-11774.
2016
-
Finding our way in the dark proteome.
138:9730-9742.
2016
-
HtrA1 proteolysis of ApoE in vitro is allele selective.
138:9473-9478.
2016
-
Hydrogen-bonded homoleptic fluoride-diarylurea complexes: structure, reactivity, and coordinating power.
138:13314-13325.
2016
-
Identification of mechanism-based inactivation in P450-catalyzed cyclopropanation facilitates engineering of improved enzymes.
138:12527-12533.
2016
-
In situ catalyst modification in atom transfer radical reactions with ruthenium benzylidene complexes.
138:7171-7177.
2016
-
Iron(II)-catalyzed intermolecular aminofluorination of unfunctionalized olefins using fluoride ion.
138:11360-11367.
2016
-
Kinetic resolution of benzylamines via palladium(II)-catalyzed C-H cross-coupling.
138:7796-7800.
2016
-
Ligand promoted meta-C-H chlorination of anilines and phenols.
138:14876-14879.
2016
-
Ligand-enabled γ-C(sp(3))-H olefination of amines: en route to pyrrolidines.
138:2055-2059.
2016
-
Ligand-promoted meta-C-H amination and alkynylation.
138:14092-14099.
2016
-
Ligand-promoted meta-C-H arylation of anilines, phenols, and heterocycles.
138:9269-9276.
2016
-
Macrocyclization of folded diamines in cavitands.
138:10846-10848.
2016
-
Metabolically labile fumarate esters impart kinetic selectivity to irreversible inhibitors.
138:15841-15844.
2016
-
Methionine ligand interaction in a blue copper protein characterized by site-selective infrared spectroscopy.
138:7187-7193.
2016
-
Oxidative entry into the illicium sesquiterpenes: enantiospecific synthesis of (+)-pseudoanisatin.
138:16616-16619.
2016
-
Palladium(II)-catalyzed regioselective syn-hydroarylation of disubstituted alkynes using a removable directing group.
138:13076-13081.
2016
-
Pd-catalyzed α-selective C-H functionalization of olefins: en route to 4-Imino-β-lactams.
138:2146-2149.
2016
-
Pd-catalyzed γ-C(sp(3))-H arylation of free amines using a transient directing group.
138:14554-14557.
2016
-
Ph(i-PrO)SiH2: An exceptional reductant for metal-catalyzed hydrogen atom transfers.
138:4962-4971.
2016
-
Practical Ni-catalyzed aryl-alkyl cross-coupling of secondary redox-active esters.
138:2174-2177.
2016
-
Radicals: reactive intermediates with translational potential.
138:12692-12714.
2016
-
Redox-active esters in Fe-catalyzed C-C coupling.
138:11132-11135.
2016
-
Replacement of 2 '-deoxycytidine by 2 '-deoxycytidine analogues in the E. coli genome.
138:14230-14233.
2016
-
Replacement of Thymidine by a Modified Base in the Escherichia coli Genome.
138:7272-7275.
2016
-
Resolution of site-specific conformational heterogeneity in proline-rich molecular recognition by Src homology 3 domains.
138:1130-1133.
2016
-
Silent encoding of chemical post-translational modifications in phage-displayed libraries.
138:32-35.
2016
-
Single hydrogen bond donation from flavin N-5 to proximal asparagine ensures FAD reduction in DNA photolyase.
138:4368-4376.
2016
-
Site-selective aliphatic C-H chlorination using N-chloroamides enables a synthesis of chlorolissoclimide.
138:696-702.
2016
-
Steric and dynamic parameters influencing in situ cycloadditions to form triazole inhibitors with crystalline acetylcholinesterase.
138:1611-1621.
2016
-
Streamlined total synthesis of uncialamycin and its application to the synthesis of designed analogues for biological investigations.
138:8235-8246.
2016
-
Structural analysis of human Argonaute-2 bound to a modified siRNA guide.
138:8694-8697.
2016
-
Structure of the ent-copalyl diphosphate synthase PtmT2 from streptomyces platensis CB00739, a bacterial type II diterpene synthase.
138:10905-10915.
2016
-
Structure-guided control of siRNA off-target effects.
138:8667-8669.
2016
-
Synthesis and biological investigation of Δ12-prostaglandin J3 (Δ12-PGJ3) analogues and related compounds.
138:6550-6560.
2016
-
Synthesis of (+)-7,20-diisocyanoadociane and liver -stage antiplasmodial activity of the isocyanoterpene class.
138:7268-7271.
2016
-
Synthesis of a potent vinblastine: rationally designed added benign complexity.
138:8376-8379.
2016
-
The dependence of carbohydrate-aromatic interaction strengths on the structure of the carbohydrate.
138:7636-7648.
2016
-
Tilted magnetic levitation enables measurement of the complete range of densities of materials with low magnetic permeability.
138:1252-1257.
2016
-
Total syntheses of aflavazole and 14-hydroxyaflavinine.
138:15555-15558.
2016
-
Trapping of the enoyl-acyl carrier protein reductase-acyl carrier protein interaction.
138:3962-3965.
2016
-
Z-Selective cross-metathesis and homodimerization of 3E-1,3-dienes: reaction optimization, computational analysis, and synthetic applications.
138:14039-14046.
2016
-
β,γ-vicinal dicarbofunctionalization of alkenyl carbonyl compounds via directed nucleopalladation.
138:15122-15125.
2016
-
A fluorinated ligand enables room-temperature and regioselective Pd-catalyzed fluorination of aryl triflates and bromides.
137:13433-13438.
2015
-
A general approach to sequence-controlled polymers using macrocyclic ring opening metathesis polymerization.
137:8038-8041.
2015
-
A synthesis of alsmaphorazine B demonstrates the chemical feasibility of a new biogenetic hypothesis.
137:7306-7309.
2015
-
Biochemical establishment and characterization of EncM's Flavin-N5-oxide cofactor.
137:8078-8085.
2015
-
CalFluors: A universal motif for fluorogenic azide probes across the visible spectrum.
137:7145-7151.
2015
-
Catalytic chemo-, regio-, and enantioselective bromochlorination of allylic alcohols.
137:3795-3798.
2015
-
Computational and experimental investigations of the formal dyotropic rearrangements of Himbert arene/allene cycloadducts.
137:6956-6964.
2015
-
Controlling the architecture, coordination, and reactivity of nanoparticle coating utilizing an amino acid central scaffold.
137:16084-16097.
2015
-
Cooperative loading and release behavior of a metal-organic receptor.
137:1770-1773.
2015
-
Drug-triggered and cross-linked self-assembling nanofibrous hydrogels.
137:4823-4830.
2015
-
Epoxide hydrolase-lasalocid a structure provides mechanistic insight into polyether natural product biosynthesis.
137:86-89.
2015
-
Genetically encoded fragment-based discovery of glycopeptide ligands for carbohydrate-binding proteins.
137:5248-5251.
2015
-
Highly selective synthesis of halomon, plocamenone, and isoplocamenone.
137:12784-12787.
2015
-
Iridium-catalyzed enantioselective allylic substitution of enol silanes from vinylogous esters and amides.
137:13972-13979.
2015
-
Modular synthetic platform for the construction of functional single-chain polymeric nanoparticles: from aqueous catalysis to photosensitization.
137:13096-13105.
2015
-
Palladium-catalyzed α,β-dehydrogenation of esters and nitriles.
137:5875-5878.
2015
-
Parahydrogen-induced polarization by pairwise replacement catalysis on Pt and Ir nanoparticles.
137:1938-1946.
2015
-
Peptide ligation and RNA cleavage via an abiotic template interface..
137:3751-3754.
2015
-
Sequence-specific, nanomolar peptide binding via cucurbit[8]uril-induced folding and inclusion of neighboring side chains.
137:3663-3669.
2015
-
Specific inhibition of microRNA processing using L-RNA aptamers.
137:16032-16037.
2015
-
Structural elucidation and synthesis of eudistidine A: an unusual polycyclic marine alkaloid that blocks interaction of the protein binding domains of p300 and HIF-1α.
137:5569-5575.
2015
-
Structure and substrate sequestration in the pyoluteorin type II peptidyl carrier protein PltL.
137:11546-11549.
2015
-
Supramolecular packing controls H-2 photocatalysis in chromophore amphiphile hydrogels.
137:15241-15246.
2015
-
Synthesis and potent antimalarial activity of kalihinol B.
137:4912-4915.
2015
-
Synthetic polymer hybridization with DNA and RNA directs nanoparticle loading, silencing delivery, and aptamer function.
137:8920-8923.
2015
-
Systematic evaluation of bioorthogonal reactions in live cells with clickable Halo Tag ligands: implications for intracellular imaging.
137:11461-11475.
2015
-
Total synthesis and biological investigation of (-)-promysalin.
137:7314-7317.
2015
-
Total synthesis of Epoxyeujindole A.
137:13764-13767.
2015
-
Total synthesis of hyperforin.
137:10516-10519.
2015
-
A deep cavitand templates lactam formation in water.
137:14582-14585.
2015
-
A fluorogenic aryl fluorosulfate for intraorganellar transthyretin imaging in living cells and in Caenorhabditis elegans.
137:7404-7414.
2015
-
A new strategy for smoking cessation: characterization of a bacterial enzyme for the degradation of nicotine.
137:10136-10139.
2015
-
A reversible and highly selective inhibitor of the proteasomal ubiquitin receptor rpn13 is toxic to multiple myeloma cells.
137:6312-6319.
2015
-
An anti-B cell maturation antigen bispecific antibody for multiple myeloma.
137:5288-5291.
2015
-
An immunosuppressive antibody-drug conjugate.
137:3229-3232.
2015
-
Chemical protein synthesis using a second-generation N-acylurea linker for the preparation of peptide-thioester precursors.
137:7197-7209.
2015
-
Cofactor-mediated conformational dynamics promote product release from Escherichia coli dihydrofolate reductase via an allosteric pathway.
137:9459-9468.
2015
-
Development of a concise synthesis of ouabagenin and hydroxylated corticosteroid analogues.
137:1330-1340.
2015
-
Fluorescence turn-on folding sensor to monitor proteome stress in live cells.
137:11303-11311.
2015
-
Highly selective, reversible inhibitor identified by comparative chemoproteomics modulates diacylglycerol lipase activity in neurons.
137:8851-8857.
2015
-
Hydromethylation of unactivated olefins.
137:8046-8049.
2015
-
Inhibition of non-ATG translational events in cells via covalent small molecules targeting RNA.
137:5336-5345.
2015
-
Kinetic profiling of catalytic organic reactions as a mechanistic tool.
137:10852-10866.
2015
-
Ligand-enabled cross-coupling of C(sp(3))-H bonds with arylsilanes.
137:4618-4621.
2015
-
Ligand-enabled meta-C-H alkylation and arylation using a modified norbornene.
137:11574-11577.
2015
-
Ligand-enabled stereoselective β-C(sp(3))-H fluorination: Synthesis of unnatural enantiopure anti-β-fluoro-α-amino acids.
137:7067-7070.
2015
-
Ligand-enabled β-C-H arylation of α-amino acids using a simple and practical auxiliary.
137:3338-3351.
2015
-
Mechanistic details of Pd(II)-catalyzed C-H iodination with molecular I-2: oxidative addition vs electrophilic cleavage.
137:9022-9031.
2015
-
Mechanistic rationalization of unusual sigmoidal kinetic profiles in the Machetti-De Sarlo cycloaddition reaction.
137:2386-2391.
2015
-
Modular degradable hydrogels based on thiol-reactive oxanorbornadiene linkers.
137:4984-4987.
2015
-
Mono-oxidation of bidentate bis-phosphines in catalyst activation: kinetic and mechanistic studies of a Pd/xantphos-catalyzed C-H functionalization.
137:13272-13281.
2015
-
Monoselective o-C-H functionalizations of mandelic acid and α-phenylglycine.
137:9877-9884.
2015
-
Origins of initiation rate differences in ruthenium olefin metathesis catalysts containing chelating benzylidenes.
137:5782-5792.
2015
-
Palladium(II)-catalyzed highly enantioselective C-H arylation of cyclopropylmethylamines.
137:2042-2046.
2015
-
Pd(II)-catalyzed C-H functionalizations directed by distal weakly coordinating functional groups.
137:4391-4397.
2015
-
Photoligation of an amphiphilic polymer with mixed coordination provides compact and reactive quantum dots.
137:5438-5451.
2015
-
Practical Pd(II)-catalyzed C-H alkylation with epoxides: one-step syntheses of 3,4-dihydroisocoumarins.
137:10950-10953.
2015
-
Rational design of antibody protease inhibitors.
137:4042-4045.
2015
-
Rational ligand design for the arylation of hindered primary amines guided by reaction progress kinetic analysis.
137:3085-3092.
2015
-
Redirection of genetically engineered CAR-T cells using bifunctional small molecules.
137:2832-2835.
2015
-
Scalable C-H oxidation with copper: synthesis of polyoxypregnanes.
137:13776-13779.
2015
-
Synthesis and biological evaluation of dimeric furanoid macroheterocycles: discovery of new anticancer agents.
137:4766-4770.
2015
-
Total syntheses and initial evaluation of [?[C(-S)NH]Tpg(4)]vancomycin, [?[C(-NH)NH]Tpg(4)]vancomycin, [?[CH2NH]Tpg(4)]vancomycin, and their (4-Chlorobiphenyl)methyl derivatives: synergistic binding pocket and peripheral modifications for the glycopeptide antibiotics.
137:3693-3704.
2015
-
Total synthesis of verruculogen and fumitremorgin a enabled by ligand-controlled C-H borylation.
137:10160-10163.
2015
-
UV and sunlight driven photoligation of quantum dots: understanding the photochemical transformation of the ligands.
137:2704-2714.
2015
-
α-Arylation of saturated azacycles and N-methylamines via palladium(II)-catalyzed C(sp(3))-H coupling.
137:11876-11879.
2015
-
γ,δ,ε-C(sp(3))-H functionalization through directed radical H-abstraction.
137:5871-5874.
2015
-
A near-IR uncaging strategy based on cyanine photochemistry.
136:14153-14159.
2014
-
A potent α/β-peptide analogue of GLP-1 with prolonged action in vivo.
136:12848-12851.
2014
-
Asymmetric Mannich synthesis of α-amino esters by anion-binding catalysis.
136:12872-12875.
2014
-
Bifacial peptide nucleic acid as an allosteric switch for aptamer and ribozyme function.
136:7265-7268.
2014
-
Characterization of native protein complexes using ultraviolet photodissociation mass spectrometry.
136:12920-12928.
2014
-
Concerted versus stepwise mechanism in thymidylate synthase.
136:9850-9853.
2014
-
Criteria for selecting PEGylation sites on proteins for higher thermodynamic and proteolytic stability.
136:17547-17560.
2014
-
Data-driven synthesis of proteolysis-resistant peptide hormones.
136:17710-17713.
2014
-
Diastereo- and enantioselective iridium-catalyzed allylation of cyclic ketone enolates: synergetic effect of ligands and barium enolates.
136:15825-15828.
2014
-
Enhancing the specificity of recombinase-mediated genome engineering through dimer interface redesign.
136:5047-5056.
2014
-
Epitope discovery for a synthetic polymer nanoparticle: a new strategy for developing a peptide tag.
136:1194-1197.
2014
-
Formal carbene insertion into C-C bond: Rh(I)-catalyzed reaction of benzocyclobutenols with diazoesters.
136:3013-3015.
2014
-
Four-step synthesis of the antimalarial cardamom peroxide via an oxygen stitching strategy.
136:5287-5290.
2014
-
Glycocalyx remodeling with proteoglycan mimetics promotes neural specification in embryonic stem cells.
136:10565-10568.
2014
-
Intramolecular [3 + 2] cyclocondensations of alkenes with indolidenes and indolidenium cations.
136:15138-15141.
2014
-
Iridium-catalyzed enantioselective allyl-alkene coupling.
136:3006-3009.
2014
-
Iron(II)-catalyzed intermolecular amino-oxygenation of olefins through the N-O bond cleavage of functionalized hydroxylamines.
136:13186-13189.
2014
-
Long-range ordering of highly charged self-assembled nanofilaments.
136:14377-14380.
2014
-
Modeling linear and cyclic PKS intermediates through atom replacement.
136:16792-16799.
2014
-
Monitoring native p38α:MK2/3 complexes via trans delivery of an ATP acyl phosphate probe.
136:4664-4669.
2014
-
Multifunctional π-expanded macrocyclic oligothiophene 6-mers and related macrocyclic oligomers.
136:2389-2396.
2014
-
Palladium-catalyzed intramolecular asymmetric C-H functionalization/cyclization reaction of metallocenes: an efficient approach toward the synthesis of planar chiral metallocene compounds.
136:4472-4475.
2014
-
Rapid, hydrolytically stable modification of aldehyde-terminated proteins and phage libraries.
136:8149-8152.
2014
-
Rational design of a non-canonical "sticky-ended" collagen triple helix.
136:7535-7538.
2014
-
Rectification in tunneling junctions: 2,2'-bipyridyl-terminated n-alkanethiolates.
136:17155-17162.
2014
-
Self-assembly of fiber-forming collagen mimetic peptides controlled by triple-helical nucleation.
136:14417-14424.
2014
-
Stereodivergent α-allylation of linear aldehydes with dual iridium and amine catalysis.
136:3020-3023.
2014
-
Synthesis of angularly substituted trans-fused hydroindanes by convergent coupling of acyclic precursors.
136:8209-8212.
2014
-
Tapping a bacterial enzymatic pathway for the preparation and manipulation of synthetic nanomaterials.
136:17378-17381.
2014
-
Total synthesis of halichondrin A, the missing member in the halichondrin class of natural products.
136:5171-5176.
2014
-
Total synthesis of rubriflordilactone A.
136:16477-16480.
2014
-
Total synthesis of taiwaniadducts B, C, and D.
136:8185-8188.
2014
-
A genetically encoded aza-Michael acceptor for covalent cross-linking of protein-receptor complexes.
136:8411-8417.
2014
-
A mechanistic change results in 100 times faster CH functionalization for ethane versus methane by a homogeneous Pt catalyst.
136:10085-10094.
2014
-
A mild, ferrocene-catalyzed C-H imidation of (hetero)arenes.
136:5279-5282.
2014
-
A practical and catalytic reductive olefin coupling.
136:1304-1307.
2014
-
A strategy for complex dimer formation when biomimicry fails: total synthesis of ten coccinellid alkaloids.
136:9743-9753.
2014
-
A unified approach to ent-atisane diterpenes and related alkaloids: synthesis of (-)-methyl atisenoate, (-)-isoatisine, and the hetidine skeleton.
136:12592-12595.
2014
-
Alkyl groups fold to fit within a water-soluble cavitand.
136:5264-5266.
2014
-
Axinellamines as broad-spectrum antibacterial agents: scalable synthesis and biology.
136:15403-15413.
2014
-
C-H methylation of heteroarenes inspired by radical SAM methyl transferase.
136:4853-4856.
2014
-
Cu(II)-mediated C-H amidation and amination of arenes: exceptional compatibility with heterocycles.
136:3354-3357.
2014
-
Cu(II)-mediated ortho C-H alkynylation of (hetero)arenes with terminal alkynes.
136:11590-11593.
2014
-
De novo-designed enzymes as small-molecule-regulated fluorescence imaging tags and fluorescent reporters.
136:13102-13105.
2014
-
Determinants of regioselective hydroxylation in the fungal polysaccharide monooxygenases.
136:562-565.
2014
-
Development of a concise synthesis of (+)-ingenol.
136:5799-5810.
2014
-
Evidence of an unusual N-H…N hydrogen bond in proteins.
136:13474-13477.
2014
-
Ligand-enabled gamma-C-H olefination and carbonylation: construction of beta-quaternary carbon centers.
136:5267-5270.
2014
-
Ligand-promoted alkylation of C(sp(3))-H and C(sp(2))-H bonds.
136:13194-13197.
2014
-
Mapping the protein interaction landscape for fully functionalized small-molecule probes in human cells.
136:10777-10782.
2014
-
Molecular rotors as conditionally fluorescent labels for rapid detection of biomolecular interactions.
136:6159-6162.
2014
-
Natural-like replication of an unnatural base pair for the expansion of the genetic alphabet and biotechnology applications.
136:826-829.
2014
-
Palau'chlor: a practical and reactive chlorinating reagent.
136:6908-6911.
2014
-
Palladium(II)-catalyzed enantioselective C(sp(3))-H activation using a chiral hydroxamic acid ligand.
136:8138-8142.
2014
-
Palladium-catalyzed meta-selective C-H bond activation with a nitrile-containing template: computational study on mechanism and origins of selectivity.
136:344-355.
2014
-
Pd(II)-catalyzed meta-C-H olefination, arylation, and acetoxylation of indolines using a U-shaped template.
136:10807-10813.
2014
-
Quantitative analysis of rRNA modifications using stable isotope labeling and mass spectrometry.
136:2058-2069.
2014
-
Rational design of CXCR4 specific antibodies with elongated CDRs.
136:10557-10560.
2014
-
Remodeling natural products: chemistry and serine hydrolase activity of a rocaglate-derived beta-lactone.
136:2659-2664.
2014
-
Role of N-acyl amino acid ligands in Pd(II)-catalyzed remote C-H activation of tethered arenes.
136:894-897.
2014
-
Selective electrocatalytic oxidation of a re-methyl complex to methanol by a surface-bound Ru(II) polypyridyl catalyst.
136:15845-15848.
2014
-
Selective monooxidation of light alkanes using chloride and iodate.
136:8393-8401.
2014
-
Simple, chemoselective hydrogenation with thermodynamic stereocontrol.
136:1300-1303.
2014
-
Simple, chemoselective, catalytic olefin isomerization.
136:16788-16791.
2014
-
Site-selective C(sp3)-H functionalization of di-, tri-, and tetrapeptides at the N-terminus.
136:16940-16946.
2014
-
Spontaneous prebiotic formation of a beta-ribofuranoside that self-assembles with a complementary heterocycle.
136:5640-5646.
2014
-
Stereoselective 1,3-insertions of rhodium(II) azavinyl carbenes.
136:195-202.
2014
-
Synthesis and biological evaluation of QRSTUVWXYZA' domains of maitotoxin.
136:16444-16451.
2014
-
Tet-mediated formation of 5-hydroxymethylcytosine in RNA.
136:11582-11585.
2014
-
Total syntheses of (-)-kopsifoline D and (-)-deoxoapodine: divergent total synthesis via late-stage key strategic bond formation.
136:3312-3317.
2014
-
Total syntheses of (-)-pyrimidoblamic acid and P-3A.
136:2119-2125.
2014
-
Total synthesis of Psi C(=NH)NH Tpg(4) vancomycin and its ((4)-chlorobiphenyl)methyl derivative: impact of peripheral modifications on vancomycin analogues redesigned for dual D-Ala-D-Ala and D-Ala-D-Lac binding.
136:13522-13525.
2014
-
Total synthesis of dixiamycin B by electrochemical oxidation.
136:5571-5574.
2014
-
Total synthesis of viridicatumtoxin B and analogues thereof: strategy evolution, structural revision, and biological evaluation.
136:12137-12160.
2014
-
Two-phase synthesis of (-)-taxuyunnanine D.
136:4909-4912.
2014
-
2-Bromopalmitate analogues as activity-based probes to explore palmitoyl acyltransferases.
135:7082-7085.
2013
-
Catalytic enantioselective dibromination of allylic alcohols.
135:12960-12963.
2013
-
Chemoproteomic discovery of cysteine-containing human short open reading frames.
135:16750-16753.
2013
-
Combinatorial generation of complexity by redox enzymes in the chaetoglobosin A biosynthesis.
135:7371-7377.
2013
-
Complete protein characterization using top-down mass spectrometry and ultraviolet photodissociation.
135:12646-12651.
2013
-
Computation and experiment reveal that the ring-rearrangement metathesis of Himbert cycloadducts can be subject to kinetic or thermodynamic control.
135:17585-17594.
2013
-
Computational design of an unnatural amino acid dependent metalloprotein with atomic level accuracy.
135:13393-13399.
2013
-
Cyclopentannulation of conjugated enones using a vinyldiazomethane-based reagent.
135:12188-12191.
2013
-
Enantioselective redox-relay oxidative Heck arylations of acyclic alkenyl alcohols using boronic acids.
135:6830-6833.
2013
-
Engineering hydrophobic protein-carbohydrate interactions to fine-tune monoclonal antibodies.
135:9723-9732.
2013
-
Hydroxyproline-free single composition ABC collagen heterotrimer.
135:6014-6017.
2013
-
Iridium-catalyzed enantioselective allylic vinylation.
135:994-997.
2013
-
Iron(II)-catalyzed intramolecular aminohydroxylation of olefins with functionalized hydroxylamines.
135:3343-3346.
2013
-
Metabolic perturbation of an essential pathway: evaluation of a glycine precursor of coenzyme A.
135:5962-5965.
2013
-
Palladium-catalyzed carbene migratory insertion using conjugated ene-yne-ketones as carbene precursors.
135:13502-13511.
2013
-
Pd-catalyzed chemoselective Catellani ortho-arylation of iodopyrroles: rapid total synthesis of rhazinal.
135:9318-9321.
2013
-
Productive chemical interaction between a bacterial microcolony couple is enhanced by periodic relocation.
135:2242-2247.
2013
-
Protein-like tertiary folding behavior from heterogeneous backbones.
135:12528-12531.
2013
-
Residue-dependent adsorption of model oligopeptides on gold.
135:15040-15052.
2013
-
Rhodium-catalyzed conversion of furans to highly functionalized pyrroles.
135:4716-4718.
2013
-
Room temperature phosphorescence of metal-free organic materials in amorphous polymer matrices.
135:6325-6329.
2013
-
Studies on the Himbert intramolecular arene/allene Diels-Alder cycloaddition. Mechanistic studies and expansion of scope to all-carbon tethers.
135:7339-7348.
2013
-
Sulfonyl 3-alkynyl pantetheinamides as mechanism-based cross-linkers of acyl carrier protein dehydratase.
135:8846-8849.
2013
-
Targeted disruption of transcriptional regulators in Chaetomium globosum activates biosynthetic pathways and reveals transcriptional regulator-like behavior of aureonitol.
135:13446-13455.
2013
-
The designability of protein switches by chemical rescue of structure: mechanisms of inactivation and reactivation.
135:18840-18849.
2013
-
Ultrafast structural dynamics inside planar phospholipid multibilayer model cell membranes measured with 2D IR spectroscopy.
135:11063-11074.
2013
-
A GTP affinity probe for proteomics highlights flexibility in purine nucleotide selectivity.
135:4676-4679.
2013
-
A Pd(0)-mediated indole (macro)cyclization reaction.
135:1600-1606.
2013
-
A dynamic structural model of expanded RNA CAG repeats: A refined X-ray structure and computational investigations using molecular dynamics and umbrella sampling simulations.
135:3528-3538.
2013
-
A genetically encoded fluorescent probe in mammalian cells.
135:12540-12543.
2013
-
Amplified halogen bonding in a small space.
135:13672-13675.
2013
-
Aromatic sulfonyl fluorides covalently kinetically stabilize transthyretin to prevent amyloidogenesis while affording a fluorescent conjugate.
135:5656-5668.
2013
-
Binding of a structured D-RNA molecule by an L-RNA aptamer.
135:13290-13293.
2013
-
Bioconjugation by native chemical tagging of C-H bonds.
135:12994-12997.
2013
-
Broadly applicable methodology for the rapid and dosable small molecule-mediated regulation of transcription factors in human cells.
135:8129-8132.
2013
-
Catalytic hydrotrifluoromethylation of unactivated alkenes.
135:2505-2508.
2013
-
Cross-coupling of remote meta-C-H bonds directed by a U-shaped template.
135:18056-18059.
2013
-
Development of a high-throughput screen and its use in the discovery of Streptococcus pneumoniae immunoglobulin A1 protease inhibitors.
135:10014-10017.
2013
-
Diced electrophoresis gel assay for screening enzymes with specified activities.
135:6002-6005.
2013
-
Dynamics of site switching in DNA polymerase.
135:4735-4742.
2013
-
Enantio- and diastereoselective synthesis of N-acetyl dihydrotetrafibricin methyl ester.
135:5340-5343.
2013
-
Enantioselective synthesis of (Z)- and (E)-2-methyl-1,5-anti-pentenediols via an allene hydroboration-double-allylboration reaction sequence.
135:9512-9517.
2013
-
Expanding the scope of replicable unnatural DNA: Stepwise optimization of a predominantly hydrophobic base pair
2013
-
Hydrogen-bonded capsules in water.
135:18064-18066.
2013
-
Ligand-accelerated ortho-C-H alkylation of arylcarboxylic acids using alkyl boron reagents.
135:17508-17513.
2013
-
Mechanistic insights into the LsrK kinase required for autoinducer-2 quorum sensing activation.
135:7827-7830.
2013
-
Mimicry of high-density lipoprotein: functional peptide-lipid nanoparticles based on multivalent peptide constructs.
135:13414-13424.
2013
-
Modulating cocaine vaccine potency through hapten fluorination.
135:2971-2974.
2013
-
Mutational analysis of 48G7 reveals that somatic hypermutation affects both antibody stability and binding affinity.
135:9980-9983.
2013
-
Palladium(0)-catalyzed alkynylation of C(sp3)-H bonds.
135:3387-3390.
2013
-
Pd(II)-catalyzed C-H iodination using molecular I2 as the sole oxidant.
135:10326-10329.
2013
-
Pd(II)-catalyzed enantioselective C-H activation/C-O bond formation: synthesis of chiral benzofuranones.
135:1236-1239.
2013
-
Pd(II)-catalyzed ortho- or meta-C-H olefination of phenol derivatives.
135:7567-7571.
2013
-
Pd(II)-catalyzed phosphorylation of aryl C-H bonds.
135:9322-9325.
2013
-
Pd-catalyzed enantioselective C-H iodination: asymmetric synthesis of chiral diarylmethylamines.
135:16344-16347.
2013
-
Post-polyketide synthase steps in iso-migrastatin biosynthesis, featuring tailoring enzymes with broad substrate specificity.
135:2489-2492.
2013
-
Production of tartrates by cyanide-mediated dimerization of glyoxylate: a potential abiotic pathway to the citric acid cycle.
135:13440-13445.
2013
-
Radical-based regioselective C-H functionalization of electron-deficient heteroarenes: scope, tunability, and predictability.
135:12122-12134.
2013
-
Rational design of fatty acid amide hydrolase inhibitors that act by covalently bonding to two active site residues.
135:6289-6299.
2013
-
Selective detection and inhibition of active caspase-3 in cells with optimized peptides.
135:12869-12876.
2013
-
Self-assembled antibody multimers through peptide nucleic acid conjugation.
135:340-346.
2013
-
Sequential C-H functionalization reactions for the enantioselective synthesis of highly functionalized 2,3-dihydrobenzofurans.
135:6774-6777.
2013
-
Site-specific antibody-polymer conjugates for siRNA delivery.
135:13885-13891.
2013
-
Small-molecule inducer of β cell proliferation identified by high-throughput screening.
135:1669-1672.
2013
-
Stilbene vinyl sulfonamides as fluorogenic sensors of and traceless covalent kinetic stabilizers of transthyretin that prevent amyloidogenesis.
135:17869-17880.
2013
-
Structural and energetic basis of carbohydrate-aromatic packing interactions in proteins.
135:9877-9884.
2013
-
Structural and thermodynamic basis of (+)-α-pinene binding to human cytochrome P450 2B6.
135:10433-10440.
2013
-
Structural insights into DNA replication without hydrogen bonds.
135:18637-18643.
2013
-
Structure and flexibility of nanoscale protein cages designed by symmetric self-assembly.
135:7738-7743.
2013
-
Synthesis of (-)-neothiobinupharidine.
135:1209-1212.
2013
-
Synthesis of biologically active N- and O-linked glycans with multisialylated poly-N-acetyllactosamine extensions using P. damsela α2-6 sialyltransferase.
135:18280-18283.
2013
-
The revolution and evolution of shotgun proteomics for large-scale proteome analysis.
135:1629-1640.
2013
-
Toward the molecular mechanism(s) by which EGCG treatment remodels mature amyloid fibrils.
135:7503-7510.
2013
-
Transannulation of 1-sulfonyl-1,2,3-triazoles with heterocumulenes.
135:4652-4655.
2013
-
Understanding the reactivity of Pd(0)/PR3-catalyzed intermolecular C(sp(3))-H bond arylation.
135:14206-14214.
2013
-
Using reduced catalysts for oxidation reactions: mechanistic studies of the "Periana-Catalytica" system for CH4 oxidation.
135:14644-14658.
2013
-
"Donor-two-acceptor" dye design: a distinct gateway to NIR fluorescence.
134:20412-20420.
2012
-
A tetradentate ligand for the enantioselective Ti(IV)-promoted oxidation of sulfides to sulfoxides: origin of enantioselectivity.
134:17354-17357.
2012
-
An endoglycosidase with alternative glycan specificity allows broadened glycoprotein remodelling.
134:8030-8033.
2012
-
Antibody-free reading of the histone code using a simple chemical sensor array.
134:11674-11680.
2012
-
Azurin as a protein scaffold for a low-coordinate nonheme iron site with a small-molecule binding pocket.
134:19746-19757.
2012
-
C-C bond formation via copper-catalyzed conjugate addition reactions to enones in water at room temperature..
134:19985-19988.
2012
-
Computational design of an α-gliadin peptidase.
134:20513-20520.
2012
-
Conformational dynamics and stability of HP35 studied with 2D IR vibrational echoes.
134:12118-12124.
2012
-
Contact de-electrification of electrostatically charged polymers.
134:20151-20159.
2012
-
Dehydratase-specific probes for fatty acid and polyketide synthases.
134:769-772.
2012
-
Design strategies for the sequence-based mimicry of side-chain display in protein β-sheets by α/β-peptides.
134:15906-15913.
2012
-
Designing allosteric control into enzymes by chemical rescue of structure.
134:10055-10060.
2012
-
Direct arylation/alkylation/magnesiation of benzyl alcohols in the presence of Grignard reagents via Ni-, Fe-, or Co-catalyzed sp3 C-O bond activation.
134:14638-14641.
2012
-
Discrete assembly of synthetic peptide-DNA triplex structures from polyvalent melamine-thymine bifacial recognition.
134:832-835.
2012
-
Enhancement of α-helix mimicry by an α/β-peptide foldamer via incorporation of a dense ionic side-chain array.
134:7317-7320.
2012
-
Evaluation of diverse α/β-backbone patterns for functional α-helix mimicry: analogues of the Bim BH3 domain.
134:315-323.
2012
-
Generation of thiocillin ring size variants by prepeptide gene replacement and in vivo processing by Bacillus cereus.
134:10313-10316.
2012
-
Improved ruthenium catalysts for Z-selective olefin metathesis.
134:693-699.
2012
-
Investigating the dearomative rearrangement of biaryl phosphine-ligated Pd(II) complexes.
134:19922-19934.
2012
-
Iridium-catalyzed enantioselective polyene cyclization.
134:20276-20278.
2012
-
Macromolecular crowding and protein stability.
134:16614-16618.
2012
-
Molecular encapsulation in pyrogallolarene hexamers under nonequilibrium conditions.
134:15000-15009.
2012
-
Photoinduced phase transfer of luminescent quantum dots to polar and aqueous media..
134:16370-16378.
2012
-
Photoreductive uncaging of fluorophore in response to protein oligomers by templated reaction in vitro and in cellulo.
134:20013-20016.
2012
-
Rational design of single-composition ABC collagen heterotrimers.
134:1430-1433.
2012
-
Self-assembly of highly ordered peptide amphiphile metalloporphyrin arrays.
134:14646-14649.
2012
-
Stereoselective synthesis of S-linked α(2→8) and α(2→8)/α(2→9) hexasialic acids.
134:16074-16079.
2012
-
Total synthesis of (-)-fusarisetin A and reassignment of the absolute configuration of its natural counterpart.
134:920-923.
2012
-
A chemical approach for cell-specific targeting of nanomaterials: Small-molecule-initiated misfolding of nanoparticle corona proteins.
134:4100-4103.
2012
-
A designer bleomycin with significantly improved DNA cleavage activity.
134:13501-13509.
2012
-
A new reagent for direct difluoromethylation.
134:1494-1497.
2012
-
A stereoselective hydroamination transform to access polysubstituted indolizidines.
134:2012-2015.
2012
-
Acyl and silyl group effects in reactivity-based one-pot glycosylation: Synthesis of embryonic stem cell surface carbohydrates lc(4) and iv(2)fuc-lc(4).
134:4549-4552.
2012
-
Alkane lengths determine encapsulation rates and equilibria.
134:8070-8073.
2012
-
Alpha-glycosylation by d-glucosamine-derived donors: Synthesis of heparosan and heparin analogues that interact with mycobacterial heparin-binding hemagglutinin.
134:8988-8995.
2012
-
Arylation of rhodium(II) azavinyl carbenes with boronic acids.
134:14670-14673.
2012
-
Asymmetric synthesis of dihydroindanes by convergent alkoxide-directed metallacycle-mediated bond formation.
134:2766-2774.
2012
-
C4-alkoxy-hpd: A potent class of synthetic modulators surpassing nature in al-2 quorum sensing.
134:13562-13564.
2012
-
Chemical and structural analysis of an antibody folding intermediate trapped during glycan biosynthesis.
134:17554-17563.
2012
-
Competitive activity-based protein profiling identifies aza-β-lactams as a versatile chemotype for serine hydrolase inhibition.
134:5068-5071.
2012
-
Concise synthetic approaches for the Laurencia family: formal total syntheses of (±)-laurefucin and (±)-E- and (±)-Z-pinnatifidenyne.
134:17714-17721.
2012
-
Confirming target engagement for reversible inhibitors in vivo by kinetically tuned activity-based probes.
134:10345-10348.
2012
-
Conformations and fluorescence of encapsulated stilbene.
134:4346-4354.
2012
-
Curtin-Hammett paradigm for stereocontrol in organocatalysis by diarylprolinol ether catalysts.
134:6741-6750.
2012
-
Degradable conjugates from oxanorbornadiene reagents.
134:6491-6497.
2012
-
Design of a bioactive small molecule that targets the myotonic dystrophy type 1 RNA via an RNA motif-ligand database and chemical similarity searching.
134:4731-4742.
2012
-
Enantioselective synthesis of anti- and syn-homopropargyl alcohols via chiral Brønsted acid catalyzed asymmetric allenylboration reactions.
134:10947-10952.
2012
-
Encapsulation of ion pairs in extended, self-assembled structures.
134:11971-11973.
2012
-
Exploratory experiments on the chemistry of the "glyoxylate scenario": Formation of ketosugars from dihydroxyfumarate.
134:3577-3589.
2012
-
Fe(III)/NaBH4-mediated free radical hydrofluorination of unactivated alkenes.
134:13588-13591.
2012
-
Fully functionalized small-molecule probes for integrated phenotypic screening and target identification.
134:10385-10388.
2012
-
Generation of candidate ligands for nicotinic acetylcholine receptors via in situ click chemistry with a soluble acetylcholine binding protein template.
134:6732-6740.
2012
-
Glycomimetic ligands for the human asialoglycoprotein receptor.
134:1978-1981.
2012
-
Guest-induced, selective formation of isomeric capsules with imperfect walls.
134:17498-17501.
2012
-
Highly stereoselective synthesis of anti,anti-dipropionate stereotriads: a solution to the long-standing problem of challenging mismatched double asymmetric crotylboration reactions.
134:3925-3931.
2012
-
In silica-aided design of a glycan ligand of sialoadhesin for in vivo targeting of macrophages.
134:15696-15699.
2012
-
Incorporation of disulfide containing protein modules into multivalent antigenic conjugates: Generation of antibodies against the thrombin-sensitive region of murine protein S.
134:19318-19321.
2012
-
Intermolecular Ritter-type C-H amination of unactivated sp3 carbons.
134:2547-2550.
2012
-
Key mechanistic features of enantioselective c-h bond activation reactions catalyzed by (chiral mono-n-protected amino acid)-pd(ii) complexes.
134:1690-1698.
2012
-
Ligand-dependent exponential amplification of a self-replicating L-RNA enzyme.
134:8050-8053.
2012
-
Ligand-enabled methylene C(sp3)-H bond activation with a Pd(II) catalyst.
134:18570-18572.
2012
-
Mechanistic rationalization of unusual kinetics in Pd-catalyzed C-H olefination.
134:4600-4606.
2012
-
New insights into the mechanism and an expanded scope of the Fe(III)-mediated vinblastine coupling reaction.
134:13240-13243.
2012
-
Oxidative cleavage of cellulose by fungal copper-dependent polysaccharide monooxygenases.
134:890-892.
2012
-
Pasteur's tweezers revisited: on the mechanism of attrition-enhanced deracemization and resolution of chiral conglomerate solids.
134:12629-12636.
2012
-
Pd(II)-catalyzed ortho trifluoromethylation of arenes and insights into the coordination mode of acidic amide directing groups.
134:11948-11951.
2012
-
Pd-catalyzed oxidative ortho-c-h borylation of arenes.
134:134-137.
2012
-
Quantitative analysis of multisite protein-ligand interactions by NMR: binding of intrinsically disordered p53 transactivation subdomains with the TAZ2 domain of CBP.
134:3792-3803.
2012
-
Quantum dots as simultaneous acceptors and donors in time-gated Förster resonance energy transfer relays: characterization and biosensing.
134:1876-1891.
2012
-
Rhodium(II)-catalyzed asymmetric sulfur(VI) reduction of diazo sulfonylamidines.
134:2477-2480.
2012
-
Ribosomal route to small-molecule diversity.
134:418-425.
2012
-
Scalable, divergent synthesis of meroterpenoids via "borono-sclareolide".
134:8432-8435.
2012
-
Seeing citrulline: Development of a phenylglyoxal-based probe to visualize protein citrullination.
134:17015-17018.
2012
-
Selective stabilization of self-assembled hydrogen-bonded molecular capsules through pi-pi interactions.
134:2914-2917.
2012
-
Silver(I)-promoted conversion of thioamides to amidines: divergent synthesis of a key series of vancomycin aglycon residue 4 amidines that clarify binding behavior to model ligands.
134:8790-8793.
2012
-
Single-molecule Förster resonance energy transfer reveals an innate fidelity checkpoint in DNA polymerase I.
134:11261-11268.
2012
-
Synthesis and biological evaluation of epidithio-, epitetrathio-, and bis-(methylthio)diketopiperazines: synthetic methodology, enantioselective total synthesis of epicoccin G, 8,8'-epi-ent-rostratin B, gliotoxin, gliotoxin G, emethallicin E, and haematocin and discovery of new antiviral and antimalarial agents.
134:17320-17332.
2012
-
Synthesis of a potent antimalarial amphilectene.
134:19604-19606.
2012
-
Synthesis of alkaloid (-)-205b via stereoselective reductive cross-coupling and intramolecular 3+2 cycloaddition.
134:15237-15240.
2012
-
Synthesis of bispecific antibodies using genetically encoded unnatural amino acids.
134:9918-9921.
2012
-
The glmS ribozyme cofactor is a general acid-base catalyst.
134:19043-19049.
2012
-
Three-component coupling sequence for the regiospecific synthesis of substituted pyridines.
134:1352-1356.
2012
-
Total syntheses of anominine and tubingensin a.
134:8078-8081.
2012
-
Total synthesis of [Psi[C(═S)NH]Tpg4]vancomycin aglycon, [Psi[C(═NH)NH]Tpg4]vancomycin aglycon, and related key compounds: reengineering vancomycin for dual D-Ala-D-Ala and D-Ala-D-Lac binding.
134:1284-1297.
2012
-
Trapping of an intermediate in the reaction catalyzed by flavin-dependent thymidylate synthase.
134:4442-4448.
2012
-
Understanding reactivity and stereoselectivity in palladium-catalyzed diastereoselective sp3 C-H bond activation: intermediate characterization and computational studies.
134:14118-14126.
2012
-
Broad distribution of energetically important contacts across an extended protein interface.
133:10038-10041.
2011
-
Combinatorially inducible RNA interference triggered by chemically modified oligonucleotides.
133:2783-2788.
2011
-
Development of proneurogenic, neuroprotective small molecules.
133:1428-1437.
2011
-
Discovery of a protein-metabolite interaction between unsaturated fatty acids and the nuclear receptor Nur77 using a metabolomics approach.
133:17168-17171.
2011
-
Divergent synthesis and chemical reactivity of bicyclic lactone fragments of complex rearranged spongian diterpenes.
133:17494-17503.
2011
-
Dual catalysis in enantioselective oxidopyrylium-based [5 + 2] cycloadditions.
133:14578-14581.
2011
-
Enantioselective total synthesis of aplyviolene.
133:16425-16427.
2011
-
Evidence for in situ catalyst modification during the Pd-catalyzed conversion of aryl triflates to aryl fluorides.
133:18106-18109.
2011
-
Hairpin folding behavior of mixed α/β-peptides in aqueous solution.
133:4246-4249.
2011
-
Lyotropic liquid crystals formed from ACHC-rich β-peptides.
133:13604-13613.
2011
-
Metal-substituted protein MRI contrast agents engineered for enhanced relaxivity and ligand sensitivity.
133:649-651.
2011
-
Molecular recognition of insulin by a synthetic receptor.
133:8810-8813.
2011
-
Monoalkylglycerol ether lipids promote adipogenesis.
133:5178-5181.
2011
-
Nucleic acid-templated energy transfer leading to a photorelease reaction and its application to a system displaying a nonlinear response.
133:18110-18113.
2011
-
Positive and negative design leads to compositional control in AAB collagen heterotrimers.
133:5432-5443.
2011
-
Protein dynamics in cytochrome P450 molecular recognition and substrate specificity using 2D IR vibrational echo spectroscopy.
133:3995-4004.
2011
-
Self-assembly and orientation of hydrogen-bonded oligothiophene polymorphs at liquid-membrane-liquid interfaces.
133:16486-16494.
2011
-
Synthesis and characterization of a series of highly fluorogenic substrates for glutathione transferases, a general strategy.
133:14109-14119.
2011
-
Temperature dependent equilibrium native to unfolded protein dynamics and properties observed with IR absorption and 2D IR vibrational echo experiments.
133:6681-6691.
2011
-
Total synthesis and biological evaluation of pederin, psymberin, and highly potent analogs.
133:16668-16679.
2011
-
Total synthesis of the Bacteroides fragilis zwitterionic polysaccharide A1 repeating unit.
133:102-107.
2011
-
Unraveling the mechanism of cascade reactions of zincke aldehydes.
133:3895-3905.
2011
-
A carbohydrate-conjugated deep cavitand permits observation of caviplexes in human serum.
133:19653-19655.
2011
-
A concise, stereocontrolled total synthesis of rippertenol.
133:8850-8853.
2011
-
A general strategy for the stereocontrolled preparation of diverse 8- and 9-membered Laurencia-type bromoethers.
133:15898-15901.
2011
-
A multivalent probe for AI-2 quorum-sensing receptors.
133:15934-15937.
2011
-
A practical synthesis of zanamivir phosphonate congeners with potent anti-influenza activity.
133:17959-17965.
2011
-
A redesigned vancomycin engineered for dual D-Ala-D-ala And D-Ala-D-Lac binding exhibits potent antimicrobial activity against vancomycin-resistant bacteria.
133:13946-13949.
2011
-
A substrate-free activity-based protein profiling screen for the discovery of selective PREPL inhibitors.
133:11665-11674.
2011
-
Activation of a water-soluble resorcinarene cavitand at the water-phosphocholine micelle interface.
133:17473-17478.
2011
-
Addressing the stereochemistry of complex organic molecules by density functional theory-NMR: vannusal B in retrospective.
133:6072-6077.
2011
-
An active-site guanine participates in glmS ribozyme catalysis in its protonated state.
133:18388-18396.
2011
-
An isothermal system that couples ligand-dependent catalysis to ligand-independent exponential amplification.
133:3191-3197.
2011
-
Atp-stimulated, DNA-mediated redox signaling by xpd, a DNA repair and transcription helicase.
133:16378-16381.
2011
-
Bent alkanes in a new thiourea-containing capsule.
133:10682-10684.
2011
-
Boronic acid hydrogen bonding in encapsulation complexes.
133:9689-9691.
2011
-
Catalytic asymmetric C-H insertions of rhodium(II) azavinyl carbenes.
133:10352-10355.
2011
-
Convergent and stereodivergent synthesis of complex 1-aza-7-oxabicyclo 2.2.1 heptanes.
133:9216-9219.
2011
-
Core-clickable peg-branch-azide bivalent-bottle-brush polymers by romp: Grafting-through and clicking-to.
133:559-566.
2011
-
Core-structure-motivated design of a phosphine-catalyzed 3+2 cycloaddition reaction: Enantioselective syntheses of spirocyclopenteneoxindoles.
133:4672-4675.
2011
-
Defining the rna internal loops preferred by benzimidazole derivatives via 2D combinatorial screening and computational analysis.
133:10111-10118.
2011
-
Design, synthesis, and validation of a β-turn mimetic library targeting protein-protein and peptide-receptor interactions.
133:10184-10194.
2011
-
Divergent c-h functionalizations directed by sulfonamide pharmacophores: Late-stage diversification as a tool for drug discovery.
133:7222-7228.
2011
-
Enantioconvergent hydroboration of a racemic allene: enantioselective synthesis of (E)-δ-stannyl-anti-homoallylic alcohols via aldehyde crotylboration.
133:5744-5747.
2011
-
Enantioselective dichlorination of allylic alcohols.
133:8134-8137.
2011
-
Enantioselective total syntheses of (-)-palau'amine, (-)-axinellamines, and (-)-massadines.
133:14710-14726.
2011
-
Enzymatic de novo pyrimidine nucleotide synthesis.
133:297-304.
2011
-
Fluoride-mediated capture of a noncovalent bound state of a reversible covalent enzyme inhibitor: X-ray crystallographic analysis of an exceptionally potent α-ketoheterocycle inhibitor of fatty acid amide hydrolase.
133:4092-4100.
2011
-
Functional virus-based polymer-protein nanoparticles by atom transfer radical polymerization.
133:9242-9245.
2011
-
Highly convergent total synthesis of (+)-lithospermic acid via a late-stage intermolecular C-H olefination.
133:5767-5769.
2011
-
Highly efficient hydrogen-bonding catalysis of the diels-alder reaction of 3-vinylindoles and methyleneindolinones provides carbazolespirooxindole skeletons.
133:12354-12357.
2011
-
Impact of distinct chemical structures for the development of a methamphetamine vaccine.
133:6587-6595.
2011
-
Incorporation of fluorotyrosines into ribonucleotide reductase using an evolved, polyspecific aminoacyl-tRNA synthetase.
133:15942-15945.
2011
-
Inverse electron demand Diels-Alder reactions of 1,2,3-triazines: Pronounced substituent effects on reactivity and cycloaddition scope.
133:12285-12292.
2011
-
Iterative in situ click chemistry assembles a branched capture agent and allosteric inhibitor for akt1.
133:18280-18288.
2011
-
Ligand-accelerated cross-coupling of C(sp2)-H bonds with arylboron reagents.
133:18183-18193.
2011
-
Ligand-promoted c-3 selective c-h olefination of pyridines with pd catalysts.
133:6964-6967.
2011
-
Ligand-promoted c3-selective arylation of pyridines with pd catalysts: Gram-scale synthesis of (+/-)-preclamol.
133:19090-19093.
2011
-
Light-induced conformational change and product release in DNA repair by (6-4) photolyase.
133:2183-2191.
2011
-
Mechanistic rationalization of organocatalyzed conjugate addition of linear aldehydes to nitro-olefins.
133:8822-8825.
2011
-
Multifunctional compact zwitterionic ligands for preparing robust biocompatible semiconductor quantum dots and gold nanoparticles.
133:9480-9496.
2011
-
Organocatalytic, enantioselective intramolecular [6+2] cycloaddition reaction for the formation of tricyclopentanoids and insight on its mechanism from a computational study.
133:20175-20185.
2011
-
Pd(II)-catalyzed enantioselective C-H activation of cyclopropanes.
133:19598-19601.
2011
-
Pd(ii)-catalyzed para-selective c-h arylation of monosubstituted arenes.
133:13864-13867.
2011
-
Pd-catalyzed intermolecular C-H amination with alkylamines.
133:7652-7655.
2011
-
Potent and selective inhibitors of glutathione S-transferase omega 1 that impair cancer drug resistance.
133:16605-16616.
2011
-
Practical C-H functionalization of quinones with boronic acids.
133:3292-3295.
2011
-
Scalable synthesis of cortistatin A and related structures.
133:8014-8027.
2011
-
Scalable, stereocontrolled total syntheses of (±)-axinellamines A and B.
133:13922-13925.
2011
-
Self-assembling small molecules form nanofibrils that bind procaspase-3 to promote activation.
133:19630-19633.
2011
-
Site-specific labeling of DNA and rna using an efficiently replicated and transcribed class of unnatural base pairs.
133:19878-19888.
2011
-
Spatiotemporal multicolor labeling of individual cells using peptide-functionalized quantum dots and mixed delivery techniques.
133:10482-10489.
2011
-
Stepwise synthesis of giant unilamellar vesicles on a microfluidic assembly line.
133:2798-2800.
2011
-
Synthesis and characterization of the arylomycin lipoglycopeptide antibiotics and the crystallographic analysis of their complex with signal peptidase.
133:17869-17877.
2011
-
Synthesis and molecular modeling provide insight into a Pseudomonas aeruginosa quorum sensing conundrum.
133:3840-3842.
2011
-
Synthesis and stereochemical determination of complestatin A and B (neuroprotectin A and B).
133:18495-18502.
2011
-
Synthesis of a trimeric gp120 epitope mimic conjugated to a t-helper peptide to improve antigenicity.
133:3230-3233.
2011
-
Synthesis of the C′D′E′F′ domain of maitotoxin.
133:214-219.
2011
-
Synthesis of the wxyza ' domain of maitotoxin.
133:220-226.
2011
-
Theoretical study of hydrogen bonding in homodimers and heterodimers of amide, boronic acid, and carboxylic acid, free and in encapsulation complexes.
133:16977-16985.
2011
-
Total synthesis and structural revision of the piperarborenines via sequential cyclobutane C-H arylation.
133:19076-19079.
2011
-
Total synthesis of epicoccin G.
133:8150-8153.
2011
-
Translational diffusion of macromolecular assemblies measured using transverse-relaxation-optimized pulsed field gradient NMR.
133:16354-16357.
2011
-
A concise enantioselective synthesis of the chlorosulfolipid malhamensilipin A.
132:2542-2543.
2010
-
Bioorthogonal chemical reporters for monitoring protein acetylation.
132:3640-3641.
2010
-
Cu(I)-amido complexes in the Ullmann reaction: reactions of Cu(I)-amido complexes with iodoarenes with and without autocatalysis by CuI.
132:15860-15863.
2010
-
Easy access to a family of polymer catalysts from modular star polymers.
132:2570-2572.
2010
-
Enzyme-catalyzed transfer of a ketone group from an S-adenosylmethionine analogue: a tool for the functional analysis of methyltransferases.
132:3642-3643.
2010
-
Expanding the chemistry of DNA for in vitro selection.
132:4141-4151.
2010
-
Expanding the dipeptidyl peptidase 4-regulated peptidome via an optimized peptidomics platform.
132:3819-3830.
2010
-
Gold-catalyzed three-component coupling: oxidative oxyarylation of alkenes.
132:8885-8887.
2010
-
Iron-catalyzed Suzuki-Miyaura coupling of alkyl halides.
132:10674-10676.
2010
-
Mechanism of the enantioselective oxidation of racemic secondary alcohols catalyzed by chiral Mn(III)-salen complexes.
132:11165-11170.
2010
-
Molecular analysis of carbohydrate-antibody interactions: case study using a Bacillus anthracis tetrasaccharide..
132:10239-10241.
2010
-
Nickel-catalyzed alkenylative cross-coupling reaction of alkyl sulfides.
132:13117-13119.
2010
-
Pd-catalyzed O-arylation of ethyl acetohydroximate: synthesis of O-arylhydroxylamines and substituted benzofurans.
132:9990-9991.
2010
-
Rapid visualization and large-scale profiling of bacterial lipoproteins with chemical reporters.
132:10628-10629.
2010
-
Selective assembly of a high stability AAB collagen heterotrimer.
132:3242-3243.
2010
-
Self-assembling multidomain peptide hydrogels: designed susceptibility to enzymatic cleavage allows enhanced cell migration and spreading.
132:3217-3223.
2010
-
Structural consequences of β-amino acid preorganization in a self-assembling α/β-peptide: fundamental studies of foldameric helix bundles.
132:12378-12387.
2010
-
Total synthesis of (+/-)- and (-)-actinophyllic acid.
132:4894-4906.
2010
-
Total synthesis of enantiopure phalarine via a stereospecific Pictet-Spengler reaction: traceless transfer of chirality from L-tryptophan.
132:8506-8512.
2010
-
Total synthesis of the antimitotic bicyclic peptide celogentin C.
132:1159-1171.
2010
-
A bacteriophage-based platform for rapid trace detection of proteases.
132:13126-13128.
2010
-
A stilbene that binds selectively to transthyretin in cells and remains dark until it undergoes a chemoselective reaction to create a bright blue fluorescent conjugate.
132:16043-16051.
2010
-
A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity.
132:1359-1370.
2010
-
Acceleration of nucleophilic ch activation by strongly basic solvents.
132:12542-12545.
2010
-
Activity-based probes that target functional subclasses of phospholipases in proteomes.
132:3264-3265.
2010
-
Asymmetric total synthesis of vindoline.
132:3685-3687.
2010
-
Asymmetric total synthesis of vindorosine, vindoline, and key vinblastine analogues.
132:13533-13544.
2010
-
Biocompatible copper(I) catalysts for in vivo imaging of glycans.
132:16893-16899.
2010
-
Botulinum neurotoxin a protease: Discovery of natural product exosite inhibitors.
132:2868-2869.
2010
-
Chemoselective reductive cross-coupling of 1,5-diene-3-ols with alkynes: A facile entry to stereodefined skipped trienes.
132:9576-9578.
2010
-
Conserved binding mode of human beta(2) adrenergic receptor inverse agonists and antagonist revealed by X-ray crystallography.
132:11443-11445.
2010
-
Context-dependent effects of asparagine glycosylation on Pin WW folding kinetics and thermodynamics.
132:15359-15367.
2010
-
Differential receptor binding affinities of influenza hemagglutinins on glycan arrays.
132:14849-14856.
2010
-
Dimeric quinidine-catalyzed enantioselective aminooxygenation of oxindoles: An organocatalytic approach to 3-hydroxyoxindole derivatives.
132:5574-5575.
2010
-
Direct C-H arylation of electron-deficient heterocycles with arylboronic acids.
132:13194-13196.
2010
-
Enantioselective synthesis of (E)-delta-stannyl homoallylic alcohols via aldehyde allylboration using alpha-stannylallylboranes generated by allene hydroboration followed by a highly diastereoselective 1,3-boratropic shift.
132:7881-7883.
2010
-
Enediyne antitumor antibiotic maduropeptin biosynthesis featuring a c-methyltransferase that acts on a coa-tethered aromatic substrate.
132:12534-12536.
2010
-
Functional characterization of ttnd and ttnf, unveiling new insights into tautomycetin biosynthesis.
132:6663-6671.
2010
-
Glycan array on aluminum oxide-coated glass slides through phosphonate chemistry.
132:13371-13380.
2010
-
Intramolecular 1+2 and 3+2 cycloaddition reactions of cyclopropenone ketals.
132:8527-8529.
2010
-
Ligand-accelerated C-H activation reactions: evidence for a switch of mechanism.
132:14137-14151.
2010
-
Modulating heme redox potential through protein-induced porphyrin distortion.
132:12794-12795.
2010
-
Mri detection of vegfr2 in vivo using a low molecular weight peptoid-(gd)(8)-dendron for targeting.
132:12829-12831.
2010
-
Multidentate poly(ethylene glycol) ligands provide colloidal stability to semiconductor and metallic nanocrystals in extreme conditions.
132:9804-9813.
2010
-
Nitric oxide synthase stabilizes the tetrahydrobiopterin cofactor radical by controlling its protonation state.
132:11812-11823.
2010
-
Nosa catalyzing carboxyl-terminal amide formation in nosiheptide maturation via an enamine dealkylation on the serine-extended precursor peptide.
132:16324-16326.
2010
-
Pd(II)-catalyzed carbonylation of C(sp3)-H bonds: a new entry to 1,4-dicarbonyl compounds.
132:17378-17380.
2010
-
Pd(II)-catalyzed enantioselective C-H olefination of diphenylacetic acids.
132:460-461.
2010
-
Pd(II)-catalyzed hydroxyl-directed C-H olefination enabled by monoprotected amino acid ligands.
132:5916-5921.
2010
-
Pd(II)-catalyzed olefination of sp(3) C-H bonds.
132:3680-3681.
2010
-
Pd(ii)-catalyzed hydroxyl-directed c-h activation/c-o cyclization: Expedient construction of dihydrobenzofurans.
132:12203-12205.
2010
-
Pd(ii)-catalyzed ortho-trifluoromethylation of arenes using tfa as a promoter.
132:3648-3649.
2010
-
Polyketide assembly by alkene-alkyne reductive cross-coupling: Spiroketals through the union of homoallylic alcohols.
132:7602-7604.
2010
-
Pterin-centered radical as a mechanistic probe of the second step of nitric oxide synthase.
132:5105-5113.
2010
-
Rapid covalent ligation of fluorescent peptides to water solubilized quantum dots.
132:10027-10033.
2010
-
Recognition of the ring-opened state of proliferating cell nuclear antigen by replication factor c promotes eukaryotic clamp-loading.
132:7372-7378.
2010
-
Ru-porphyrin protein scaffolds for sensing o(2).
132:5582-5583.
2010
-
Scalable total syntheses of N-linked tryptamine dimers by direct indole-aniline coupling: Psychotrimine and kapakahines B and F.
132:7119-7137.
2010
-
Selective recognition and extraction of the uranyl ion.
132:13572-13574.
2010
-
Self-assembled quantum dot-sensitized multivalent DNA photonic wires.
132:18177-18190.
2010
-
Simple reagents for direct halonium-induced polyene cyclizations.
132:14303-14314.
2010
-
Supramolecular control of fluorescence through reversible encapsulation.
132:9984-9985.
2010
-
Synthesis and characterization of a cyclobutane duocarmycin derivative incorporating the 1,2,10,11-tetrahydro-9H-cyclobuta[c]benzo[e]indol-4-one (CbBI) alkylation subunit.
132:13936-13940.
2010
-
Synthesis and reactivity of rhodium(ii) n-triflyl azavinyl carbenes.
132:2510-2511.
2010
-
Synthesis of the ABCDEFG ring system of maitotoxin.
132:6855-6861.
2010
-
Synthesis of the QRSTU domain of maitotoxin and its 85-epi- and 86-epi-diastereoisomers.
132:9900-9907.
2010
-
Synthetic applications of Pd(II)-catalyzed C-H carboxylation and mechanistic insights: expedient routes to anthranilic acids, oxazolinones, and quinazolinones.
132:686-693.
2010
-
Tailored ligand acceleration of the Cu-catalyzed azide-alkyne cycloaddition reaction: practical and mechanistic implications.
132:14570-14576.
2010
-
Total synthesis and biological evaluation of the resveratrol-derived polyphenol natural products hopeanol and hopeahainol a.
132:7540-7548.
2010
-
Total synthesis and evaluation of a key series of C5-substituted vinblastine derivatives.
132:8489-8495.
2010
-
Total synthesis and structural revision of vannusals A and B: synthesis of the originally assigned structure of vannusal B.
132:7138-7152.
2010
-
Total synthesis and structural revision of vannusals A and B: synthesis of the true structures of vannusals A and B.
132:7153-7176.
2010
-
Total synthesis of (+)-fendleridine (aspidoalbidine) and (+)-1-acetylaspidoalbidine.
132:3009-3012.
2010
-
Total synthesis of complestatin: development of a Pd(0)-mediated indole annulation for macrocyclization.
132:7776-7783.
2010
-
Total synthesis of echinopines a and b.
132:3815-3818.
2010
-
Total synthesis of englerin a.
132:8219-8222.
2010
-
Total synthesis of lehualide b by allylic alcohol-alkyne reductive cross-coupling.
132:11422-11424.
2010
-
Total synthesis of sporolide B and 9-epi-sporolide B.
132:11350-11363.
2010
-
Total synthesis, assignment of the relative and absolute stereochemistry, and structural reassignment of phostriecin (aka Sultriecin).
132:2157-2159.
2010
-
Tyrosine bioconjugation through aqueous ene-type reactions: A click-like reaction for tyrosine.
132:1523-1525.
2010
-
Unusual inverse temperature dependence on reaction rate in the asymmetric autocatalytic alkylation of pyrimidyl aldehydes.
132:15104-15107.
2010
-
Unusual reversal of enantioselectivity in the proline-mediated alpha-amination of aldehydes induced by tertiary amine additives.
132:7598-7899.
2010
-
Visualizing the reaction coordinate of an O-GlcNAc hydrolase.
132:1807-1809.
2010
-
An antibody-recruiting small molecule that targets HIV gp120.
131:16392-+.
2009
-
An α/β-peptide helix bundle with a pure β3-amino acid core and a distinctive quaternary structure.
131:9860-9861.
2009
-
Buckled membranes in mixed-valence ionic amphiphile vesicles.
131:12030-12031.
2009
-
Chiral Brønsted acid-catalyzed enantioselective alpha-hydroxylation of beta-dicarbonyl compounds.
131:4562-4563.
2009
-
Complex polycyclic lactams from pericyclic cascade reactions of Zincke aldehydes.
131:7546-7547.
2009
-
Conditional RNA interference mediated by allosteric ribozyme.
131:13906-13907.
2009
-
Consecutive intramolecular hydroamination/asymmetric transfer hydrogenation under relay catalysis of an achiral gold complex/chiral Bronsted acid binary system.
131:9182-+.
2009
-
EPR and ENDOR characterization of the reactive intermediates in the generation of NO by cryoreduced oxy-nitric oxide synthase from Geobacillus stearothermophilus.
131:14493-14507.
2009
-
Efficient access to the core of the Strychnos, Aspidosperma and Iboga alkaloids. A short synthesis of norfluorocurarine.
131:3472-3473.
2009
-
Escherichia coli allows efficient modular incorporation of newly isolated quinomycin biosynthetic enzyme into echinomycin biosynthetic pathway for rational design and synthesis of potent antibiotic unnatural natural product.
131:9347-9353.
2009
-
Identification of an overabundant cholesterol precursor in hepatitis B virus replicating cells by untargeted lipid metabolite profiling.
131:5030-5031.
2009
-
Imaging of mRNA in live cells using nucleic acid-templated reduction of azidorhodamine probes.
131:6492-6497.
2009
-
In vitro imaging and in vivo liver targeting with carbohydrate capped quantum dots.
131:2110-2112.
2009
-
Lipid membrane adhesion and fusion driven by designed, minimally multivalent hydrogen-bonding lipids.
131:16919-16926.
2009
-
Organocatalytic synthesis of spiro[pyrrolidin-3,3'-oxindoles] with high enantiopurity and structural diversity.
131:13819-13825.
2009
-
Relative stereochemistry determination and synthesis of the major chlorosulfolipid from Ochromonas danica.
131:7570-7572.
2009
-
Relaxation dynamics of Pseudomonas aeruginosa Re(I)(CO)3(alpha-diimine)(HisX)(+) (X = 83, 107, 109, 124, 126)Cu(II) azurins.
131:11788-11800.
2009
-
Ring-closing metathesis of allylsilanes/electrophilic desilylation to prepare exo-methylidenecycloalkanes. Short syntheses of teucladiol and poitediol.
131:15090-15091.
2009
-
Stereoselective synthesis and osteogenic activity of subglutinols A and B.
131:3192-3194.
2009
-
Synthesis of S-linked alpha(2-->9) octasialic acid via exclusive alpha S-glycosidic bond formation.
131:3138-3139.
2009
-
Total synthesis of (-)-acutumine.
131:6674-6675.
2009
-
Toward homogeneous erythropoietin: chemical synthesis of the Ala1-Gly28 glycopeptide domain by "alanine" ligation.
131:5438-5443.
2009
-
"Too small, too big, and just right" - optical sensing of molecular conformations in self-assembled capsules.
131:13190-13191.
2009
-
A convergent stereoselective synthesis of quinolizidines and indolizidines: Chemoselective coupling of 2-hydroxymethyl-substituted allylic silanes with imines.
131:17548-17549.
2009
-
A short and efficient synthesis of (-)-7-methylomuralide, a potent proteasome inhibitor.
131:5746-5747.
2009
-
A suite of activity-based probes for human cytochrome P450 enzymes.
131:10692-10700.
2009
-
Bifunctional acyltransferase/decarboxylase lnmk as the missing link for beta-alkylation in polyketide biosynthesis.
131:6900-6901.
2009
-
Binding and inactivation mechanism of a humanized fatty acid amide hydrolase by alpha-ketoheterocycle inhibitors revealed from cocrystal structures.
131:10497-10506.
2009
-
Boron nitride nanotubes are noncytotoxic and can be functionalized for interaction with proteins and cells.
131:890-891.
2009
-
Buckyballs meet viral nanoparticles: Candidates for biomedicine.
131:17093-17095.
2009
-
Characterization of the sgcf epoxide hydrolase supporting an (r)-vicinal diol intermediate for enediyne antitumor antibiotic c-1027 biosynthesis.
131:16410-16417.
2009
-
Concise synthesis of iminocyclitols via petasis-type aminocyclization.
131:8352-8353.
2009
-
Controlling the specificity of modularly assembled small molecules for RNA via ligand module spacing: Targeting the RNAs that cause myotonic muscular dystrophy.
131:17464-17472.
2009
-
Defining the mode of action of tetramic acid antibacterials derived from Pseudomonas aeruginosa quorum sensing signals.
131:14473-14479.
2009
-
Design, synthesis, and evaluation of an α-helix mimetic library targeting protein-protein interactions.
131:5564-5572.
2009
-
Design, synthesis, biological evaluation, and structural characterization of potent histone deacetylase inhibitors based on cyclic alpha/beta-tetrapeptide architectures.
131:3033-3041.
2009
-
Direct observation of an enamine intermediate in amine catalysis.
131:18206-18207.
2009
-
Direct observation of ligand dynamics in cytochrome c.
131:6054-6055.
2009
-
Direct observation of structural heterogeneity in a β-sheet.
131:5726-5727.
2009
-
Discovery of inhibitors of aberrant gene transcription from libraries of DNA binding molecules: Inhibition of LEF-1-mediated gene transcription and oncogenic transformation.
131:3342-3348.
2009
-
Enantioselective intramolecular Friedel−Crafts-type α-arylation of aldehydes.
131:2086-2087.
2009
-
Enantioselective synthesis of 2-methyl-1,2-syn- and 2-methyl-1,2-anti-3-butenediols via allene hydroboration-aldehyde allylboration reaction sequences.
131:14602-14603.
2009
-
Enantioselective total synthesis of (-)-napyradiomycin A1 via asymmetric chlorination of an isolated olefin.
131:5744-5745.
2009
-
Enantiospecific total syntheses of kapakahines B and F.
131:6360-6361.
2009
-
Enzymatic synthesis and structural characterization of 13C, 15N-poly(ADP-ribose).
131:14571-14578.
2009
-
Evolution of proteins with genetically encoded "chemical warheads".
131:9616-9617.
2009
-
Explorations into neolignan biosynthesis: concise total syntheses of helicterin B, helisorin, and helisterculin A from a common intermediate.
131:1745-1752.
2009
-
Genetic incorporation of a metal-ion chelating amino acid into proteins as a biophysical probe.
131:2481-2483.
2009
-
Genetic incorporation of a small, environmentally sensitive, fluorescent probe into proteins in Saccharomyces cerevisiae.
131:12921-12923.
2009
-
Identification of a new endogenous metabolite and the characterization of its protein interactions through an immobilization approach.
131:378-386.
2009
-
Invariant polymorphism in virus capsid assembly.
131:2606-2614.
2009
-
Lactimidomycin, iso-migrastatin and related glutarimide-containing 12-membered macrolides are extremely potent inhibitors of cell migration.
131:1370-1371.
2009
-
Microfluidic device for single-molecule experiments with enhanced photostability.
131:13610-13612.
2009
-
Mixing and matching detergents for membrane protein NMR structure determination.
131:7320-7326.
2009
-
NMR characterization of membrane protein-detergent micelle solutions by use of microcoil equipment.
131:18450-18456.
2009
-
New synthetic technologies for the construction of heterocycles and tryptamines.
131:3690-3699.
2009
-
Optimization of an unnatural base pair toward natural-like replication.
131:3246-3252.
2009
-
Oxy-functionalization of nucleophilic rhenium(I) metal carbon bonds catalyzed by selenium(IV).
131:2466-2468.
2009
-
PCR with an expanded genetic alphabet.
131:14620-14621.
2009
-
Pd(0)/PR(3)-catalzed intermolecular arylation of sp(3) C-H bonds.
131:9886-9887.
2009
-
Pd(II)-catalyzed amination of C-H bonds using single-electron or two-electron oxidants.
131:10806-10807.
2009
-
Pd(ii)-catalyzed hydroxylation of arenes with 1 atm of o(2) or air.
131:14654-14655.
2009
-
Pd(ii)-catalyzed olefination of electron-deficient arenes using 2,6-dialkylpyridine ligands.
131:5072-5074.
2009
-
Possible origin of electronic effects in rh(i)-catalyzed enantioselective hydrogenation.
131:9604-9605.
2009
-
Prediction of the rotational tumbling time for proteins with disordered segments.
131:6814-6821.
2009
-
Probing synergy between two catalytic strategies in the glycoside hydrolase O-GlcNAcase using multiple linear free energy relationships.
131:13415-13422.
2009
-
Probing the dynamics of the p1 helix within the tetrahymena group i intron.
131:9571-9578.
2009
-
Probing the folding transition state structure of the villin headpiece subdomain via side chain and backbone mutagenesis.
131:7470-7476.
2009
-
Product protection, the key to developing high performance methane selective oxidation catalysts.
131:17110-17115.
2009
-
Pseudo-capsule assemblies characterized by (19)f NMR techniques.
131:2440-2441.
2009
-
Rational design of ligands targeting triplet repeating transcripts that cause RNA dominant disease: Application to myotonic muscular dystrophy type 1 and spinocerebellar ataxia type 3.
131:9767-9779.
2009
-
Recognition and organocatalysis with a synthetic cavitand receptor.
131:7402-7410.
2009
-
Revisiting AI-2 quorum sensing inhibitors: Direct comparison of alkyl-DPD analogues and a natural product fimbrolide.
131:15584-15585.
2009
-
Rhodium-catalyzed enantioselective cyclopropanation of olefins with N-sulfonyl 1,2,3-triazoles.
131:18034-18035.
2009
-
Scalable total synthesis and biological evaluation of haouamine a and its atropisomer.
131:9172-9173.
2009
-
Selective toxin sequestrants for the treatment of bacterial infections.
131:5760-5762.
2009
-
Stereoselective synthesis of gamma-substituted (Z)-allylic boranes via kinetically controlled hydroboration of allenes with 10-TMS-9-borabicyclo[3.3.2]decane.
131:14174-14175.
2009
-
Synthesis at the interface of chemistry and biology.
131:12497-12515.
2009
-
Tandem application of virtual screening and NMR experiments in the discovery of brand new DNA quadruplex groove binders.
131:16336-16337.
2009
-
The second step of the nitric oxide synthase reaction: Evidence for ferric-peroxo as the active oxidant.
131:297-305.
2009
-
Thiol-selective fluorogenic probes for labeling and release.
131:9986-9994.
2009
-
Thiourea-catalyzed highly enantio- and diastereoselective additions of oxindoles to nitroolefins: Application to the formal synthesis of (+)-physostigmine.
131:8758-8759.
2009
-
Total syntheses of (+/-)-platencin and (-)-platencin.
131:15909-15917.
2009
-
Total synthesis and biological evaluation of (+)- and (-)-bisanthraquinone antibiotic BE-43472B and related compounds.
131:14812-14826.
2009
-
Total synthesis and biological evaluation of cortistatins a and j and analogues thereof.
131:10587-10597.
2009
-
Total synthesis and evaluation of iso-duocarmycin SA and iso-yatakemycin.
131:1187-1194.
2009
-
Total synthesis and structure elucidation of (+)-phorbasin c.
131:1392-1393.
2009
-
Total synthesis of chloropeptin II (complestatin) and chloropeptin I.
131:16036-16038.
2009
-
Total synthesis of diverse carbogenic complexity within the resveratrol class from a common building block.
131:1753-1765.
2009
-
Total synthesis of platensimycin and related natural products.
131:16905-16918.
2009
-
Total synthesis of vinblastine, vincristine, related natural products, and key structural analogues.
131:4904-4916.
2009
-
Total synthesis of vinigrol.
131:17066-17067.
2009
-
Transcription of an expanded genetic alphabet.
131:5046-5047.
2009
-
Transition-state charge transfer reveals electrophilic, ambiphilic, and nucleophilic carbon-hydrogen bond activation.
131:11686-11688.
2009
-
Universal translators for nucleic acid diagnosis.
131:9368-9377.
2009
-
Versatile Pd(OTf)2 x 2 H2O-catalyzed ortho-fluorination using NMP as a promoter.
131:7520-7521.
2009
-
A global metabolite profiling approach to identify protein-metabolite interactions.
130:14111-14113.
2008
-
A templating approach for monodisperse self-assembled organic nanostructures.
130:2742-2743.
2008
-
Analysis of the cryptophycin P450 epoxidase reveals substrate tolerance and cooperativity.
130:5492-5498.
2008
-
Application of affinity selection/mass spectrometry to determine the structural isomer of parnafungins responsible for binding polyadenosine polymerase.
130:16704-16710.
2008
-
Enantioselective total syntheses of nankakurines A and B: confirmation of structure and establishment of absolute configuration.
130:11297-11299.
2008
-
Engineering complex riboswitch regulation by dual genetic selection.
130:16310-16315.
2008
-
Fluorescent profiling of modular biosynthetic enzymes by complementary metabolic and activity based probes.
130:5443-5445.
2008
-
Functional determinants of a synthetic vesicle fusion system.
130:6196-6205.
2008
-
Genetically encoding protein oxidative damage.
130:4028-4033.
2008
-
Intra- and intermembrane pairwise molecular recognition between synthetic hydrogen-bonding phospholipids.
130:14456-14458.
2008
-
Minimally cationic cell-permeable miniature proteins via α-helical arginine display.
130:2948-2949.
2008
-
Origins of enhanced proton transport in the Y7F mutant of human carbonic anhydrase II.
130:11399-11408.
2008
-
Self-assembling peptide coatings designed for highly luminescent suspension of single-walled carbon nanotubes.
130:17134-17140.
2008
-
Self-assembly of α-helical coiled coil nanofibers.
130:13691-13695.
2008
-
Solution phase measurement of both weak sigma and C-H center dot center dot center dot X- hydrogen bonding interactions in synthetic anion receptors.
130:10895-10897.
2008
-
Stereocontrolled synthesis of Z-dienes via an unexpected pericyclic cascade rearrangement of 5-amino-2,4-pentadienals.
130:7560-7561.
2008
-
Stereoselective dichlorination of allylic alcohol derivatives to access key stereochemical arrays of the chlorosulfolipids.
130:12514-12518.
2008
-
Synthetic collagen heterotrimers: structural mimics of wild-type and mutant collagen type I.
130:7509-7515.
2008
-
Time-resolved dimerization of a PAS-LOV protein measured with photocoupled small angle X-ray scattering.
130:12226-12227.
2008
-
Total synthesis and molecular target of largazole, a histone deacetylase inhibitor.
130:8455-8459.
2008
-
Total synthesis of (+/-)-actinophyllic acid.
130:7568-7569.
2008
-
1,3-diol synthesis via controlled, radical-mediated C-H functionalization.
130:7247-7249.
2008
-
A concise asymmetric total synthesis of aspidophytine.
130:14942-14943.
2008
-
A general and efficient method for the site-specific dual-labeling of proteins for single molecule fluorescence resonance energy transfer.
130:17664-17665.
2008
-
A peptoid "antibody surrogate" that antagonizes VEGF receptor 2 activity.
130:5744-5752.
2008
-
A single-molecule nanopore device detects DNA polymerase activity with single-nucleotide resolution.
130:818-820.
2008
-
An additional spirocyclization for duocarmycin SA.
130:16521-16523.
2008
-
An expedient asymmetric synthesis of platencin.
130:11292-11293.
2008
-
An unexpected switch in the modulation of AI-2-based quorum sensing discovered through synthetic 4,5-dihydroxy-2,3-pentanedione analogues.
130:9200-9201.
2008
-
Bifunctional CD22 ligands use multimeric immunoglobulins as protein scaffolds in assembly of immune complexes on B cells.
130:7736-7745.
2008
-
Biosynthesis of a site-specific DNA cleaving protein.
130:13194-13195.
2008
-
Carbon-deuterium bonds as probes of dihydrofolate reductase.
130:6597-6603.
2008
-
Catalysis of 3-pyrrolidinecarboxylic acid and related pyrrolidine derivatives in enantioselective anti-mannich-type reactions: Importance of the 3-acid group on pyrrolidine for stereocontrol.
130:875-886.
2008
-
Characterization of the two-component, fad-dependent monooxygenase sgcc that requires carrier protein-tethered substrates for the biosynthesis of the enediyne antitumor antibiotic c-1027.
130:6616-6623.
2008
-
Chemical synthesis and biological evaluation of palmerolide a analogues.
130:10019-10023.
2008
-
Chemical synthesis of a glycoprotein having an intact human complex-type sialyloligosaccharide under the Boc and Fmoc synthetic strategies.
130:501-510.
2008
-
Chemical synthesis of the GHIJKLMNO ring system of maitotoxin.
130:7466-7476.
2008
-
Conversion of allylic alcohols to stereodefined trisubstituted alkenes: A complementary process to the claisen rearrangement.
130:16870-16872.
2008
-
Design, synthesis, and biological evaluation of platensimycin analogues with varying degrees of molecular complexity.
130:13110-13119.
2008
-
Direct coupling of catharanthine and vindoline to provide vinblastine: Total synthesis of (+)- and ent-(-)-vinblastine.
130:420-421.
2008
-
Discovery, characterization, and optimization of an unnatural base pair for expansion of the genetic alphabet.
130:2336-2343.
2008
-
Emergence of a single solid chiral state from a nearly racemic amino acid derivative.
130:1158-1159.
2008
-
Enantiospecific total synthesis of the hapalindoles, fischerindoles, and welwitindolinones via a redox economic approach.
130:17938-17954.
2008
-
Evolution of solid phase homochirality for a proteinogenic amino acid.
130:15274-15275.
2008
-
In situ generation of a bisubstrate analogue for protein arginine methyltransferase 1.
130:4574-4575.
2008
-
In vivo incorporation of unnatural amino acids to probe structure, dynamics, and ligand binding in a large protein by nuclear magnetic resonance spectroscopy.
130:9268-9281.
2008
-
Influence of remote asymmetric centers in reversible encapsulation complexes.
130:2450-2451.
2008
-
Interactions between redox complexes and semiconductor quantum dots coupled via a peptide bridge.
130:16745-16756.
2008
-
Intermolecular enolate heterocoupling: Scope, mechanism, and application.
130:11546-11560.
2008
-
Microscale NMR screening of new detergents for membrane protein structural biology.
130:7357-7363.
2008
-
On-virus construction of polyvalent glycan ligands for cell-surface receptors.
130:4578-4579.
2008
-
Optimization of activity-based probes for proteomic profiling of histone deacetylase complexes.
130:2184-2194.
2008
-
Organocatalysis in a synthetic receptor with an inwardly directed carboxylic acid.
130:5658-5659.
2008
-
Pd(II)-catalyzed cross-coupling of sp3 C-H Bonds with sp2 and sp3 boronic acids using air as the oxidant.
130:7190-7191.
2008
-
Plasma clearance of bacteriophage Qβ particles as a function of surface charge.
130:1328-1334.
2008
-
Quantitative microarray analysis of intact glycolipid-CD1d interaction and correlation with cell-based cytokine production.
130:12348-12354.
2008
-
Reaction of carboxylic acids and isonitriles in small spaces.
130:7810-7811.
2008
-
Reaction of isonitriles with carboxylic acids in a cavitand: Observation of elusive isoimide intermediates.
130:11850-11851.
2008
-
Rhodium-catalyzed transannulation of 1,2,3-triazoles with nitriles.
130:14972-14974.
2008
-
Ruthenium-catalyzed azide-alkyne cycloaddition: scope and mechanism.
130:8923-8930.
2008
-
Selecting folded proteins from a library of secondary structural elements.
130:176-185.
2008
-
Sialoside analogue arrays for rapid identification of high affinity siglec ligands.
130:6680-6681.
2008
-
Stability, dynamics, and selectivity in the assembly of hydrogen-bonded hexameric capsules.
130:2344-2350.
2008
-
Sugar-assisted glycopeptide ligation with complex oligosaccharides: Scope and limitations.
130:11945-11952.
2008
-
Synthesis of (+)-cortistatin A.
130:7241-7243.
2008
-
Synthesis of 1,2- and 1,3-dicarboxylic acids via Pd(II)-catalyzed carboxylation of aryl and vinyl C-H bonds.
130:14082-14083.
2008
-
Synthesis of β-, γ-, and δ-Lactams via Pd(II)-catalyzed C−H activation reaction.
130:14058-14059.
2008
-
Targeting large kinase active site with rigid, bulky octahedral ruthenium complexes.
130:15764-5.
2008
-
The role of tandem acyl carrier protein domains in polyunsaturated fatty acid biosynthesis.
130:6336-6337.
2008
-
The structure of a TNA-TNA complex in solution: NMR study of the octamer duplex derived from alpha-(L)-threofuranosyl-(3 '-2 ')-CGAATTCG.
130:15105-15115.
2008
-
Total syntheses of (+)-tedanolide and (+)-13-deoxytedanolide.
130:16407-16416.
2008
-
Total syntheses of (+/-)-massadine and massadine chloride.
130:16490-16491.
2008
-
Total synthesis of (+)-superstolide A.
130:2722-2723.
2008
-
Total synthesis of (+/-)-psychotrimine.
130:10886-10887.
2008
-
Total synthesis of biologically active natural products.
130:6654-6656.
2008
-
Total synthesis of chlorofusin, its seven chromophore diastereomers, and key partial structures.
130:12355-12369.
2008
-
Total synthesis of the originally proposed and revised structures of palmerolide a and isomers thereof.
130:3633-3644.
2008
-
Total synthesis, revised structure, and biological evaluation of biyouyanagin A and analogues thereof.
130:11114-11121.
2008
-
Toward a chemical mechanism of proton pumping by the B-type cytochrome c oxidases: application of density functional theory to cytochrome ba(3) of Thermus thermophilus.
130:15002-15021.
2008
-
Two-dimensional combinatorial screening identifies specific aminoglycoside - RNA internal loop partners.
130:11185-11194.
2008
-
Unnatural substrate repertoire of a, b, and x family DNA polymerases.
130:14872-14882.
2008
-
Versatile Pd(II)-catalyzed C-H activation/aryl-aryl coupling of benzoic and phenyl acetic acids.
130:17676-17677.
2008
-
A new mechanism for benzopyrone formation in aromatic polyketide biosynthesis.
129:9304-9305.
2007
-
Biophysical and structural characterization of a robust octameric β-peptide bundle.
129:14746-14751.
2007
-
Biophysical characterization of a β-peptide bundle: Comparison to natural proteins.
129:5344-5345.
2007
-
Design and synthesis of a BODIPY-alpha-tocopherol adduct for use as an off/on fluorescent antioxidant indicator.
129:1842-1843.
2007
-
Design of a functional membrane protein by engineering a heme-binding site in glycophorin A.
129:512-518.
2007
-
Different apolipoproteins impact nanolipoprotein particle formation.
129:14348-14354.
2007
-
Discrete heterogeneous quaternary structure formed by α/β-peptide foldamers and α-peptides.
129:6376-6377.
2007
-
Gold-catalyzed deoxygenated cyclization of cis-2,4-dien-1-als with regioselective addition of two nucleophiles. One-pot synthesis of highly functionalized cyclopentene framework.
129:3798-3799.
2007
-
Helix bundle quaternary structure from α/β-peptide foldamers.
129:4178-4180.
2007
-
High-resolution structure of a β-peptide bundle.
129:1532-1533.
2007
-
Highly selective Diels-Alder reactions of directly connected enyne dienophiles.
129:645-657.
2007
-
Intrinsically cell-permeable miniature proteins based on a minimal cationic PPII motif.
129:14578-14579.
2007
-
Practical synthesis of enantiomerically pure β2)-amino acids via proline-catalyzed diastereoselective aminomethylation of aldehydes.
129:6050-6055.
2007
-
Prediction of the 3D structure and dynamics of human DP G-protein coupled receptor bound to an agonist and an antagonist.
129:10720-10731.
2007
-
Reactivation of the p53 tumor suppressor pathway by a stapled p53 peptide.
129:2456-2457.
2007
-
Reengineering a natural riboswitch by dual genetic selection.
129:13814-13815.
2007
-
Self-assembled heterotrimeric collagen triple helices directed through electrostatic interactions.
129:2683-2690.
2007
-
Self-assembly of multidomain peptides: Balancing molecular frustration controls conformation and nanostructure.
129:12468-12472.
2007
-
Sila Morita-Baylis-Hillman reaction of cyclopropenes.
129:14868-14869.
2007
-
Surprisingly high stability of collagen ABC heterotrimer: Evaluation of side chain charge pairs.
129:15034-15041.
2007
-
Tethering small molecules to a phage display library: discovery of a selective bivalent inhibitor of protein kinase A.
129:13812-13813.
2007
-
The hydrophobic effect drives the recognition of hydrocarbons by an anionic metal-ligand cluster.
129:12094-12095.
2007
-
8-Azaguanine reporter of purine ionization states in structured RNAs.
129:3426-3432.
2007
-
A functional proteomic strategy to discover inhibitors for uncharacterized hydrolases.
129:9594-9595.
2007
-
A unique class of duocarmycin and CC-1065 analogues subject to reductive activation.
129:15391-15397.
2007
-
Alanine scan of [L-Dap2]ramoplanin A2 aglycon: Assessment of the importance of each residue.
129:8747-8755.
2007
-
Analysis of PUGNAc and NAG-thiazoline as transition state analogues for human O-GlcNAcase: mechanistic and structural insights into inhibitor selectivity and transition state poise.
129:635-644.
2007
-
Anomeric reactivity-based one-pot synthesis of heparin-like oligosaccharides.
129:12795-12800.
2007
-
Antibody-catalyzed oxidation of delta(9)-tetrahydrocannabinol.
129:3698-3702.
2007
-
Assembly and exchange of resorcinarene capsules monitored by fluorescence resonance energy transfer.
129:3818-3819.
2007
-
Benzimidazole and related ligands for Cu-catalyzed azide-alkyne cycloaddition.
129:12696-12704.
2007
-
Bifunctional catalysis of proton transfer at an antibody active site.
129:460-461.
2007
-
Biomimetic catalysis of intermodular aminoacyl transfer.
129:748-749.
2007
-
Cavitands with introverted functionality stabilize tetrahedral intermediates.
129:15639-15643.
2007
-
Characterization of NcsB2 as a promiscuous naphthoic acid/coenzyme A ligase integral to the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin.
129:7728-7729.
2007
-
Characterization of the maduropeptin biosynthetic gene cluster from actinomadura madurae atcc 39144 supporting a unifying paradigm for enediyne biosynthesis.
129:13082-13094.
2007
-
Clarification of the role of water in proline-mediated aldol reactions.
129:15100-15101.
2007
-
Contrasting two- and three-dimensional crystal properties of isomeric dialkyl phthalates.
129:15211-15217.
2007
-
Crystal structure of a biosynthetic sulfo-hirudin complexed to thrombin.
129:10648-10649.
2007
-
D-fructose-6-phosphate aldolase-catalyzed one-pot synthesis of iminocyclitols.
129:14811-14817.
2007
-
Design and synthesis of c5 methylated l-arginine analogues as active site probes for nitric oxide synthase.
129:12563-12570.
2007
-
Detection of reactive tetrahedral intermediates in a deep cavitand with an introverted functionality.
129:15330-15339.
2007
-
Direct catalytic asymmetric synthesis of anti-1,2-amino alcohols and syn-1,2-diols through organocatalytic anti-mannich and syn-aldol reactions.
129:288-289.
2007
-
Efforts toward expansion of the genetic alphabet: structure and replication of unnatural base pairs.
129:10466-10473.
2007
-
Emergence of solution-phase homochirality via crystal engineering of amino acids.
129:7657-7660.
2007
-
Enrichment tags for enhanced-resolution profiling of the polar metabolome.
129:15780-15782.
2007
-
Extended sugar-assisted glycopeptide ligations: Development, scope, and applications.
129:13527-13536.
2007
-
Extraction of hydrophobic species into a water-soluble synthetic receptor.
129:13464-13473.
2007
-
Fourier transform infrared characterization of a cu-b-nitrosyl complex in cytochrome ba3 from thermus thermophilus: Relevance to no reductase activity in heme-copper terminal oxidases.
129:14952-14958.
2007
-
Functional and mechanistic analyses of biomimetic aminoacyl transfer reactions in de novo designed coiled coil peptides via rational active site engineering.
129:2959-2966.
2007
-
Guest recognition with micelle-bound cavitands.
129:9773-9779.
2007
-
Identification of a peptoid inhibitor of the proteasome 19S regulatory particle.
129:7750-7751.
2007
-
In vivo site-specific DNA methylation with a designed sequence-enabled DNA methylase.
129:8676-8677.
2007
-
Label transfer chemistry for the characterization of protein-protein interactions.
129:12348-12349.
2007
-
Ligand-accelerated Cu-catalyzed azide-alkyne cycloaddition: a mechanistic report.
129:12705-12712.
2007
-
Methylrhenium trioxide revisited: mechanisms for nonredox oxygen insertion in an M-CH3 bond.
129:15794-15804.
2007
-
Minor groove hydrogen bonds and the replication of unnatural base pairs.
129:5551-5557.
2007
-
Modular multi-level circuits from immobilized DNA-based logic gates.
129:14875-14879.
2007
-
Palladium-catalyzed methylation and arylation of sp2 and sp3 C-H bonds in simple carboxylic acids.
129:3510-3511.
2007
-
Periodate-triggered cross-linking reveals Sug2/Rpt4 as the molecular target of a peptoid inhibitor of the 19S proteasome regulatory particle.
129:12936-12937.
2007
-
Quantitative analysis of carbohydrate-protein interactions using glycan microarrays: Determination of surface and solution dissociation constants.
129:11177-11184.
2007
-
Quantitative evaluation of the relative cell permeability of peptoids and peptides.
129:1508-1509.
2007
-
Rational design, synthesis, and evaluation of key analogues of CC-1065 and the duocarmycins.
129:14092-14099.
2007
-
Regio- and stereoselective cross-coupling of substituted olefins and imines. A convergent stereoselective synthesis of saturated 1,5-aminoalcohols and substituted piperidines.
129:7514-7516.
2007
-
Regiospecific chlorination of (s)-ss-tyrosyl-s-carrier protein catalyzed by sgcc3 in the biosynthesis of the enediyne antitumor antibiotic c-1027.
129:12432-12438.
2007
-
Remarkable loop flexibility in avian influenza N1 and its implications for antiviral drug design.
129:7764-7765.
2007
-
Rhenium(vii) oxide catalyzed heteroacylative ring-opening dimerization of tetrahydrofuran.
129:1246-1253.
2007
-
Scope and mechanism of direct indole and pyrrole couplings adjacent to carbonyl compounds: Total synthesis of acremoauxin A and oxazinin 3.
129:12857-12869.
2007
-
Self-assembly dynamics of a cylindrical capsule monitored by fluorescence resonance energy transfer.
129:8818-8824.
2007
-
Sequence-specific resonance assignment of soluble nonglobular proteins by 7D APSY-NMR Spectroscopy.
129:10823-10828.
2007
-
Site-specific insertion of 3-aminotyrosine into subunit α2 of E. coli ribonucleotide reductase: direct evidence for involvement of Y(730) and Y(731) in radical propagation.
129:15060-15071.
2007
-
Solution NMR studies of the maturation intermediates of a 13 MDa viral capsid.
129:7867-7876.
2007
-
Structural and initial biological analysis of synthetic arylomycin A(2).
129:15830-15838.
2007
-
Sugar-assisted ligation in glycoprotein synthesis.
129:7690-7701.
2007
-
Synthesis of 5-fluoropyrimidine nucleotides as sensitive NMR probes of RNA structure.
129:14911-14921.
2007
-
Synthesis of potent bicyclic bisarylimidazole c-jun N-terminal kinase inhibitors by catalytic C-H bond activation.
129:490-491.
2007
-
Synthesis of substituted 1,4-dienes by direct alkylation of allylic alcohols.
129:15112-15113.
2007
-
Synthesis of tamiflu and its phosphonate congeners possessing potent anti-influenza activity.
129:11892-11893.
2007
-
Systematic exploration of the structural features of yatakemycin impacting DNA alkylation and biological activity.
129:10858-10869.
2007
-
Tailored glycoproteomics and glycan site mapping using saccharide-selective bioorthogonal probes.
129:7266-7267.
2007
-
Tailoring relaxation dispersion experiments for fast-associating protein complexes.
129:13406-13407.
2007
-
The case of the missing ring: Radical cleavage of a carbon-carbon bond and implications for gfp chromophore biosynthesis.
129:3118-3126.
2007
-
The mechanism of mio-based aminomutases in beta-amino acid biosynthesis.
129:15744-15745.
2007
-
Total syntheses of 2,2 '-epi-cytoskyrin a, rugulosin, and the alleged structure of rugulin.
129:4001-4013.
2007
-
Total synthesis and antibacterial properties of carbaplatensimycin.
129:14850-14851.
2007
-
Total synthesis of abyssomicin c, atrop-abyssomicin c, and abyssomicin d: Implications for natural origins of atrop-abyssomicin c.
129:429-440.
2007
-
Total synthesis of dimeric pyrrole-imidazole alkaloids: Sceptrin, ageliferin, nagelamide e, oxysceptrin, nakamuric acid, and the axinellamine carbon skeleton.
129:4762-4775.
2007
-
Total synthesis of kinamycins C, F, and J.
129:10356-10357.
2007
-
Total synthesis of marinomycins A-C and of their monomeric counterparts monomarinomycin A and iso-monomarinomycin A.
129:1760-1768.
2007
-
Total synthesis, stereochemical reassignment, and absolute configuration of chlorofusin.
129:9860-9861.
2007
-
A simple γ-backbone modification preorganizes peptide nucleic acid into a helical structure.
128:10258-10267.
2006
-
An α-helical peptidomimetic inhibitor of the HIV-1 Rev-RRE interaction.
128:3496-3497.
2006
-
Circumventing the problems caused by protein diversity in microarrays: Implications for protein interaction networks.
128:13668-13669.
2006
-
Convergent, enantioselective syntheses of guanacastepenes A and E featuring a selective cyclobutane fragmentation.
128:7025-7035.
2006
-
Cyclic peptide helices: A hybrid beta-hairpin/beta-helical supersecondary structure.
128:10650-10651.
2006
-
Direct nucleophilic acylation of nitroalkenes promoted by a fluoride anion/thiourea combination.
128:4932-4933.
2006
-
Enantioselective TADMAP-catalyzed carboxyl migration reactions for the synthesis of stereogenic quaternary carbon.
128:925-934.
2006
-
Excited-state dynamics of structurally characterized [Re-I(CO)(3)(phen)(HisX)](+) (X=83,109) Pseudomonas aeruginosa azurins in aqueous solution.
128:4365-4370.
2006
-
Membrane activation: selective vesicle fusion via small molecule recognition.
128:14430-14431.
2006
-
Non-uniformly sampled double-TROSY hNcaNH experiments for NMR sequential assignments of large proteins.
128:5757-5763.
2006
-
Self-assembly of peptide-amphiphile nanofibers: The roles of hydrogen bonding and amphiphilic packing.
128:7291-7298.
2006
-
Solvent isotope effects on interfacial protein electron transfer in crystals and electrode films.
128:2346-2355.
2006
-
Synthesis and evaluation of bioorthogonal pantetheine analogues for in vivo protein modification.
128:12174-12184.
2006
-
Synthesis of taiwaniaquinoids via Nazarov triflation.
128:11022-11023.
2006
-
Uncovering quantitative protein interaction networks for mouse PDZ domains using protein microarrays.
128:5913-5922.
2006
-
"Click" chemistry in a supramolecular environment: stabilization of organogels by copper(I)-catalyzed azide-alkyne [3 + 2] cycloaddition.
128:6056-6057.
2006
-
3-pyrrolidinecarboxylic acid for direct catalytic asymmetric anti-Mannich-type reactions of unmodified ketones.
128:9630-9631.
2006
-
A fluoroacetamidine-based inactivator of protein arginine deiminase 4: Design, synthesis, and in vitro and in vivo evaluation.
128:1092-1093.
2006
-
A genetically encoded fluorescent amino acid.
128:8738-8739.
2006
-
A genetically encoded infrared probe.
128:13984-13985.
2006
-
A reversible reaction inside a self-assembled capsule.
128:9308-9309.
2006
-
A synthetic mimic of protein inner space: Buried polar interactions in a deep water-soluble host.
128:15366-15367.
2006
-
Activity-based protein profiling reagents for protein arginine deiminase 4 (pad4): Synthesis and in vitro evaluation of a fluorescently labeled probe.
128:14468-14469.
2006
-
Amide-to-E-olefin versus amide-to-ester backbone H-bond perturbations: evaluating the O-O repulsion for extracting H-bond energies.
128:15948-15949.
2006
-
Amino acid dependent formation of phosphate anhydrides in water mediated by carbonyl sulfide.
128:20-21.
2006
-
An alkoxide-directed carbometalation of internal alkynes.
128:2764-2765.
2006
-
An efficiently extended class of unnatural base pairs.
128:6780-6781.
2006
-
Antibody interference with N-acyl homoserine lactone-mediated bacterial quorum sensing.
128:2802-2803.
2006
-
Asymmetric total synthesis of (+)- and ent-(-)-yatakemycin and duocarmycin SA: evaluation of yatakemycin key partial structures and its unnatural enantiomer.
128:15683-15696.
2006
-
Carboxylic solvents and O-donor ligand effects on CH activation by Pt(II).
128:7404-7405.
2006
-
Cavitands with revolving doors regulate binding selectivities and rates in water.
128:3894-3895.
2006
-
Chemistry of periodate-mediated cross-linking of 3,4-dihydroxylphenylalanine-containing molecules to proteins.
128:15228-15235.
2006
-
Coiled molecules in spring loaded devices.
128:15038-15039.
2006
-
Concise total syntheses of palominol, dolabellatrienone, beta-araneosene, and isoedunol via an enantioselective Diels-Alder macrobicyclization.
128:740-742.
2006
-
Cu(ii)-catalyzed functionalizations of aryl c-h bonds using o-2 as an oxidant.
128:6790-6791.
2006
-
Delineation of a fundamental alpha-ketoheterocycle substituent effect for use in the design of enzyme inhibitors.
128:14004-14005.
2006
-
Diastereoselective Diels-Alder reactions of N-sulfonyl-1-aza-1,3-butadienes with optically active enol ethers: An asymmetric variant of the 1-azadiene Diels-Alder reaction.
128:2587-2593.
2006
-
Direct and high resolution characterization of cytochrome c equilibrium folding.
128:14232-14233.
2006
-
Direct asymmetric anti-mannich-type reactions catalyzed by a designed amino acid.
128:1040-1041.
2006
-
Discovery of EGFR selective 4,6-disubstituted pyrimidines from a combinatorial kinase-directed heterocycle library.
128:2182-2183.
2006
-
Efforts toward developing direct probes of protein dynamics.
128:6028-6029.
2006
-
Enantioselective total synthesis of avrainvillamide and the stephacidins.
128:8678-8693.
2006
-
Expanded capsules with reversibly added spacers.
128:5314-5315.
2006
-
Facile functionalization of a metal carbon bond by O-atom transfer.
128:9018-9019.
2006
-
Fluorescent sensors for organophosphorus nerve agent mimics.
128:4500-4501.
2006
-
Fluorescent signal amplification of carbocyanine dyes using engineered viral nanoparticles.
128:5184-5189.
2006
-
Infrared line shape of an alpha-carbon deuterium-labeled amino acid.
128:13334-13335.
2006
-
Intramolecular Diels-Alder/1,3-dipolar cycloaddition cascade of 1,3,4-oxadiazoles.
128:10589-10595.
2006
-
Measurement of long-range 1H-19F scalar coupling constants and their glycosidic torsion dependence in 5-fluoropyrimidine-substituted RNA.
128:5851-5858.
2006
-
Mechanistic implications of pseudo zero order kinetics in kinetic resolutions.
128:7450-7451.
2006
-
Molecular organization of cholesterol in unsaturated phosphatidylethanolamines: X-ray diffraction and solid state h-2 NMR reveal differences with phosphatidylcholines.
128:5375-5383.
2006
-
New RNA labeling methods offer dramatic sensitivity enhancements in 2H NMR relaxation spectra.
128:9346-9347.
2006
-
Nucleophilic catalysis of hydrazone formation and transimination: implications for dynamic covalent chemistry.
128:15602-15603.
2006
-
Optimization of unnatural base pair packing for polymerase recognition.
128:6369-6375.
2006
-
Organocatalytic direct asymmetric aldol reactions in water.
128:734-735.
2006
-
Organocatalytic direct michael reaction of ketones and aldehydes with beta-nitrostyrene in brine.
128:4966-4967.
2006
-
Palladium-catalyzed alkylation of aryl c-h bonds with sp(3) organotin reagents using benzoquinone as a crucial promoter.
128:78-79.
2006
-
Palladium-catalyzed alkylation of sp(2) and sp(3) c-h bonds with methylboroxine and alkylboronic acids: Two distinct c-h activation pathways.
128:12634-12635.
2006
-
Physical controls on directed virus assembly at nanoscale chemical templates.
128:10801-10807.
2006
-
Redox-coupled dynamics and folding in cytochrome c.
128:7909-7915.
2006
-
Reevaluation of the mechanism of the amination of aryl halides catalyzed by BINAP-ligated palladium complexes.
128:3584-3591.
2006
-
Rieske protein from thermus thermophilus: N-15 NMR titration study demonstrates the role of iron-ligated histidines in the ph dependence of the reduction potential.
128:10672-10673.
2006
-
Sensitive and selective detection of nitric oxide using an h-nox domain.
128:10022-10023.
2006
-
Structural evidence for an enolate intermediate in gfp fluorophore biosynthesis.
128:3166-3168.
2006
-
Structure-based discovery of glycolipids for CD1d-mediated NKT cell activation: Tuning the adjuvant versus immunosuppression activity.
128:9022-9023.
2006
-
Sugar-assisted glycopeptide ligation.
128:5626-5627.
2006
-
Sugar-assisted ligation of N-linked glycopeptides with broad sequence tolerance at the ligation junction.
128:15026-15033.
2006
-
Superactivation of the botulinum neurotoxin serotype A light chain metalloprotease: A new wrinkle in botulinum neurotoxin.
128:4176-4177.
2006
-
Synthesis of degradable model networks via atrp and click chemistry.
128:6564-6565.
2006
-
Synthetic seleno-glutaredoxin 3 analogues are highly reducing oxidoreductases with enhanced catalytic efficiency.
128:16684-16691.
2006
-
The bifunctional glyceryl transferase/phosphatase ozmb belonging to the had superfamily that diverts 1,3-bisphosphoglycerate into polyketide biosynthesis.
128:10386-10387.
2006
-
The genetic incorporation of a distance probe into proteins in Escherichia coli.
128:4572-4573.
2006
-
The incorporation of a photoisomerizable amino acid into proteins in E. coli.
128:388-389.
2006
-
The putative endocannabinoid transport blocker LY2183240 is a potent inhibitor of FAAH and several other brain serine hydrolases.
128:9699-9704.
2006
-
The two-state issue in the mixed-valence binuclear cu-a center in cytochrome c oxidase and n2o reductase.
128:16452-16453.
2006
-
Total synthesis and biological evaluation of halipeptins a and d and analogues.
128:4460-4470.
2006
-
Total synthesis and evaluation of [Ψ[CH(2)NH]Tpg(4)]vancomycin aglycon: reengineering vancomycin for dual D-Ala-D-Ala and D-Ala-D-Lac binding.
128:2885-2892.
2006
-
Total synthesis and evaluation of cytostatin, its C10-C11 diastereomers, and additional key analogues: Impact on PP2A inhibition.
128:16720-16732.
2006
-
Total synthesis and structural elucidation of azaspiracid-1. Construction of key building blocks for originally proposed structure.
128:2244-2257.
2006
-
Total synthesis and structural elucidation of azaspiracid-1. Final assignment and total synthesis of the correct structure of azaspiracid-1.
128:2859-2872.
2006
-
Total synthesis and structural elucidation of azaspiracid-1. Synthesis-based analysis of originally proposed structures and indication of their non-identity to the natural product.
128:2258-2267.
2006
-
Total synthesis of (+/-)-chartelline C.
128:14028-14029.
2006
-
Total synthesis of (+/-)-haouamine A.
128:3908-3909.
2006
-
Total synthesis of (-)- and ent-(+)-vindoline and related alkaloids.
128:10596-10612.
2006
-
Total synthesis of amphidinolide E.
128:15960-15961.
2006
-
Total synthesis of piericidin A1 and B1 and key analogues.
128:11799-11807.
2006
-
Understanding GFP posttranslational chemistry: Structures of designed variants that achieve backbone fragmentation, hydrolysis, and decarboxylation.
128:4685-4693.
2006
-
Unexpected acetylcholinesterase activity of cocaine esterases.
128:15364-15365.
2006
-
Biomimetic synthesis of antimalarial naphthoquinones.
127:6276-6283.
2005
-
Conformational substates modulate hydride transfer in dihydrofolate reductase.
127:12997-13006.
2005
-
Design, synthesis, and biological evaluation of HSP90 inhibitors based on conformational analysis of radicicol and its analogues.
127:6999-7004.
2005
-
Determination of the packing mode of the coiled-coil domain of cGMP-Dependent protein kinase I alpha in solution using charge-predicted dipolar couplings.
127:11918-11919.
2005
-
Importance of tensor asymmetry for the analysis of (2)H NMR spectra from deuterated aromatic rings.
127:17488-17493.
2005
-
In vivo reporter labeling of proteins via metabolic delivery of coenzyme A analogues.
127:11234-11235.
2005
-
Rhodopsin reconstituted into a planar-supported lipid bilayer retains photoactivity after cross-linking polymerization of lipid monomers.
127:5320-5321.
2005
-
Tryptophan side chain electrostatic interactions determine edge-to-face vs parallel-displaced tryptophan side chain geometries in the designed β-hairpin "trpzip2".
127:4668-4674.
2005
-
(4,2)D projection-reconstruction experiments for protein backbone assignment: application to human carbonic anhydrase II and calbindin D(28K).
127:8785-8795.
2005
-
A deep cavitand provides a structured environment for the menschutkin reaction.
127:11222-11223.
2005
-
A designed synthetic analogue of 4-OT is specific for a non-natural substrate.
127:5862-5868.
2005
-
A dimerization "switch" in the internalization mechanism of a cell-penetrating peptide.
127:538-539.
2005
-
A pentenyl dianion-based strategy for convergent synthesis of ene-1,5-diols.
127:3694-3695.
2005
-
A potent transactivation domain mimic with activity in living cells.
127:8254-8255.
2005
-
A tandem orthogonal proteolysis strategy for high-content chemical proteomics.
127:10018-10019.
2005
-
Active site structure of class I ribonucleotide reductase intermediate X: a density functional theory analysis of structure, energetics, and spectroscopy.
127:15778-15790.
2005
-
Antibody-catalyzed asymmetric intramolecular michael addition of aldehydes and ketones to yield the disfavored cis-product.
127:13104-13105.
2005
-
Biosynthesis of the beta-amino acid moiety of the enediyne antitumor antibiotic c-1027 featuring beta-amino acyl-s-carrier protein intermediates.
127:11594-11595.
2005
-
CH activation with an O-donor iridium-methoxo complex.
127:14172-14173.
2005
-
Cloning, sequencing, analysis, and heterologous expression of the fredericamycin biosynthetic gene cluster from streptomyces griseus.
127:16442-16452.
2005
-
Controlling the morphology of cross beta-sheet assemblies by rational design.
127:8562-8570.
2005
-
Copper(I)-catalyzed synthesis of azoles. DFT study predicts unprecedented reactivity and intermediates.
127:210-216.
2005
-
Cysteine-derived organocatalyst in a highly enantioselective intramolecular Michael reaction.
127:16028-16029.
2005
-
Cysteine-derived organocatalyst in a highly enantioselective intramolecular michael reaction.
127:16028-16029.
2005
-
Decomposition of triacetone triperoxide is an entropic explosion.
127:1146-1159.
2005
-
Deep cavitands provide organized solvation of reactions.
127:11904-11905.
2005
-
Differential solvation and tautomer stability of a model base pair within the minor and major grooves of DNA.
127:15612-15617.
2005
-
Discovery of a biologically active thiostrepton fragment.
127:15042-15044.
2005
-
E-olefin dipeptide isostere incorporation into a polypeptide backbone enables hydrogen bond perturbation: probing the requirements for Alzheimer's amyloidogenesis.
127:15366-15367.
2005
-
Elucidation of fatty acid amide hydrolase inhibition by potent alpha-ketoheterocycle derivatives from Monte Carlo simulations.
127:17377-17384.
2005
-
Enantioselective total syntheses of welwitindolinone A and fischerindoles I and G.
127:15394-15396.
2005
-
Experimental evidence for chair-like transition states in aldol reactions of methyl ketone lithium enolates: stereoselective synthesis and utilization of a deuterium-labeled enolate as a probe of reaction stereochemistry.
127:5770-5771.
2005
-
Fluorescent cocaine probes: A tool for the selection and engineering of therapeutic antibodies.
127:2477-2484.
2005
-
In situ selection of lead compounds by click chemistry: Target-guided optimization of acetylcholinesterase inhibitors.
127:6686-6692.
2005
-
Iso-migrastatin congeners from streptomyces platensis and generation of a glutarimide polyketide library featuring the dorrigocin, lactimidomycin, migrastatin, and nk30424 scaffolds.
127:11930-11931.
2005
-
Kinetic stabilization of an oligomeric protein by a single ligand binding event.
127:5540-5551.
2005
-
Luminescent ruthenium(II)- and rhenium(I)-diimine wires bind nitric oxide synthase.
127:5169-5173.
2005
-
Migrastatin and dorrigocins are shunt metabolites of iso-migrastatin.
127:1622-1623.
2005
-
O-GlcNAcase catalyzes cleavage of thioglycosides without general acid catalysis.
127:17202-17203.
2005
-
Origin of selectivity in the antibody 20f10-catalyzed yang cyclization.
127:132-145.
2005
-
Parallel biomolecular computation on surfaces with advanced finite automata.
127:3935-3943.
2005
-
Polymerase evolution: Efforts toward expansion of the genetic code.
127:12470-12471.
2005
-
Potent and selective structure-based dibenzofuran inhibitors of transthyretin amyloidogenesis: Kinetic stabilization of the native state.
127:6662-6671.
2005
-
Redox couples of inducible nitric oxide synthase.
127:11212-11213.
2005
-
Remarkable phosphine-effect on the intramolecular aldol reactions of unsaturated 1,5-diketones: highly regioselective synthesis of cross-conjugated dienones.
127:16778-16779.
2005
-
Ruthenium-catalyzed cycloaddition of alkynes and organic azides.
127:15998-15999.
2005
-
Structural characterization of a p-acetylphenylalanyl aminoacyl-tRNA synthetase.
127:14976-14977.
2005
-
Synthesis, structure, and reactivity of O-donor Ir(III) complexes: C-H activation studies with benzene.
127:11372-11389.
2005
-
The allylic azide rearrangement: achieving selectivity.
127:13444-13445.
2005
-
The role of chelating diamine ligands in the goldberg reaction: a kinetic study on the copper-catalyzed amidation of aryl iodides.
127:4120-4121.
2005
-
The total synthesis of coleophomones B, C, and D.
127:8872-8888.
2005
-
Total synthesis of (+)-13-deoxytedanolide.
127:6186-6187.
2005
-
Total synthesis of asimicin via highly stereoselective [3 + 2] annulation reactions of substituted allylsilanes.
127:10818-10819.
2005
-
Total synthesis of ningalin D.
127:10767-10770.
2005
-
Total synthesis of piericidin A1 and B1.
127:15704-15705.
2005
-
Total synthesis of thiostrepton. Assembly of key building blocks and completion of the synthesis.
127:11176-11183.
2005
-
Total synthesis of thiostrepton. Retrosynthetic analysis and construction of key building blocks.
127:11159-11175.
2005
-
Toward cocaine esterase therapeutics.
127:10016-10017.
2005
-
Tuning the enantioselective N-acetylation of racemic amines: A spectacular salt effect.
127:6138-6139.
2005
-
Virus crystals as nanocomposite scaffolds.
127:5274-5275.
2005
-
Why are BINOL-based monophosphites such efficient ligands in Rh-catalyzed asymmetric olefin hydrogenation?.
127:10305-10313.
2005
-
Designing sequence to control protein function in an EF-hand protein.
126:5990-5998.
2004
-
Electron transfer between cytochrome c and cytochome c peroxidase in single crystals.
126:10836-10837.
2004
-
Enantioselective formal hydration of α,β-unsaturated imides by Al-catalyzed conjugate addition of oxime nucleophiles.
126:14724-14725.
2004
-
Metal-assisted assembly and stabilization of collagen-like triple helices.
126:15030-15031.
2004
-
NMR structure of a cyclic polyamide-DNA complex.
126:7958-7966.
2004
-
Nonspecific medium effects versus specific group positioning in the antibody and albumin catalysis of the base-promoted ring-opening reactions of benzisoxazoles.
126:8197-8205.
2004
-
Oligothiophene isocyanides for platinum-based molecular electronic applications.
126:11796-11797.
2004
-
Palladium-catalyzed synthesis of N-aryl-2-benzylindolines via tandem arylation of 2-allylaniline: control of selectivity through in situ catalyst modification.
126:13906-13907.
2004
-
Precursor-directed biosynthesis of epothilone in Escherichia coli.
126:7436-7437.
2004
-
Structural mining: self-consistent design on flexible protein-peptide docking and transferable binding affinity potential.
126:8515-8528.
2004
-
The effect of mutation on RNA Diels-Alderases.
126:11843-11851.
2004
-
A catalysis-based selection for peroxidase antibodies with increased activity.
126:3006-3007.
2004
-
A functionalized, deep cavitand catalyzes the aminolysis of a choline derivative.
126:7424-7425.
2004
-
A genetically encoded photocaged amino acid.
126:14306-14307.
2004
-
A high-resolution probe of protein folding.
126:3384-3385.
2004
-
A new method for the stereoselective synthesis of α- and β-glycosylamines using the burgess reagent.
126:6234-6235.
2004
-
A phage display system with unnatural amino acids.
126:15962-15963.
2004
-
A powerful selection assay for mixture libraries of DNA alkylating agents.
126:9194-9195.
2004
-
A precipitator for the detection of thiophilic metals in aqua.
126:16582-16586.
2004
-
Antisymmetric exchange in 2fe-2s (1+) clusters: Epr of the rieske protein from thermus thermophilus at ph 14.
126:5338-5339.
2004
-
Biomimetically inspired total synthesis and structure activity relationships of 1-o-methyllateriflorone. 6 pi electrocyclizations in organic synthesis.
126:5493-5501.
2004
-
Boolean logic functions of a synthetic peptide network.
126:11140-11141.
2004
-
Calculating the electron paramagnetic resonance parameters of exchange coupled transition metal complexes using broken symmetry density functional theory: application to a MnIII/MnIV model compound.
126:2613-2622.
2004
-
Catalysis by a synthetic receptor sealed at one end and functionalized at the other.
126:16280-16281.
2004
-
Chemistry and biology of diazonamide A: First total synthesis and confirmation of the true structure.
126:12888-12896.
2004
-
Chemistry and biology of diazonamide A: Second total synthesis and biological investigations.
126:12897-12906.
2004
-
Covalent display of oligosaccharide arrays in microtiter plates.
126:8640-8641.
2004
-
Cyclic amidine sugars as transition-state analogue inhibitors of glycosidases: Potent competitive inhibitors of mannosidases.
126:1971-1979.
2004
-
Dedifferentiation of lineage-committed cells by a small molecule.
126:410-411.
2004
-
Design and use of fluorogenic aldehydes for monitoring the progress of aldehyde transformations.
126:3692-3693.
2004
-
Detection of bacteria with carbohydrate-functionalized fluorescent polymers.
126:13343-13346.
2004
-
Development of a functionalized xenon biosensor.
126:15287-15294.
2004
-
Direct coupling of indoles with carbonyl compounds: Short, enantioselective, gram-scale synthetic entry into the hapalindole and fischerindole alkaloid families.
126:7450-7451.
2004
-
Discovery and characterization of catalysts for azide-alkyne cycloaddition by fluorescence quenching.
126:9152-9153.
2004
-
Dissecting ramoplanin: mechanistic analysis of synthetic ramoplanin analogues as a guide to the design of improved antibiotics.
126:7462-7463.
2004
-
Effects of lipid chain lengths in alpha-galactosylceramides on cytokine release by natural killer T cells.
126:13602-13603.
2004
-
Efforts to expand the genetic alphabet: Identification of a replicable unnatural DNA self-pair.
126:6923-6931.
2004
-
Electrostatic interactions dominate the catalytic contribution of Arg39 in 4-oxalocrotonate tautomerase.
126:12726-12727.
2004
-
Enzymatic synthesis and 19F NMR studies of 2-fluoroadenine-substituted RNA.
126:11776-11777.
2004
-
Equilibrium isotope effects as a probe of nonbonding attractions.
126:11428-11429.
2004
-
Establishing the parabolic relationship between reactivity and activity for derivatives and analogues of the duocarmycin and CC-1065 alkylation subunits.
126:80-81.
2004
-
Evidence for a post-translational modification, aspartyl aldehyde, in a photosynthetic membrane protein.
126:8399-8405.
2004
-
Expanding the substrate repertoire of a DNA polymerase by directed evolution.
126:1748-1754.
2004
-
Helical folding of alkanes in a self-assembled, cylindrical capsule.
126:13512-13518.
2004
-
Heterocyclic peptide backbone modifications in an α-helical coiled coil.
126:15366-15367.
2004
-
Hydrogen-bonded encapsulation complexes in protic solvents.
126:14149-14156.
2004
-
Immunological consequences of methamphetamine protein glycation.
126:11446-11447.
2004
-
In situ catalyst improvement in the proline-mediated alpha-amination of aldehydes.
126:11770-11771.
2004
-
In situ click chemistry: Enzyme inhibitors made to their own specifications.
126:12809-12818.
2004
-
Inhibition of the proteolytic activity of anthrax lethal factor by aminoglycosides.
126:4774-4775.
2004
-
Isotopomer encapsulation in a cylindrical molecular capsule: A probe for understanding noncovalent isotope effects on a molecular level.
126:7738-7739.
2004
-
Kinetically stable complexes in water: The role of hydration and hydrophobicity.
126:2870-2876.
2004
-
Kinetics and thermodynamics of hexameric capsule formation.
126:2939-2943.
2004
-
Mapping enzyme active sites in complex proteomes.
126:1363-1368.
2004
-
Mechanically regulated rotation of a guest in a nanoscale host.
126:12728-12729.
2004
-
Mechanism of homogeneous Ir(III) catalyzed regioselective arylation of olefins.
126:352-363.
2004
-
Mechanistic analysis of hydroarylation catalysts.
126:11658-11665.
2004
-
Mechanistic investigation leads to a synthetic improvement in the hydrolytic kinetic resolution of terminal epoxides.
126:1360-1362.
2004
-
Microarray platform for profiling enzyme activities in complex proteomes.
126:15640-15641.
2004
-
On the role of the conserved aspartate in the hydrolysis of the phosphocysteine intermediate of the low molecular weight tyrosine phosphatase.
126:12677-12684.
2004
-
Optimization of interstrand hydrophobic packing interactions within unnatural DNA base pairs.
126:14419-14427.
2004
-
Periodate-triggered cross-linking of dopa-containing peptide-protein complexes.
126:11442-11443.
2004
-
Photolithographic synthesis of peptoids.
126:4088-4089.
2004
-
Porphyrin distortion during affinity maturation of a ferrochelatase antibody, monitored by resonance Raman spectroscopy.
126:16361-16367.
2004
-
Probing the active catalyst in product-accelerated proline-mediated reactions.
126:16312-16313.
2004
-
Selective derivatization and sequestration of ribose from a prebiotic mix.
126:9578-9583.
2004
-
Short total synthesis of (+/-)-sceptrin.
126:3726-3727.
2004
-
Single molecule solvation and its effects on tautomeric equilibria in a self-assembled capsule.
126:8956-8960.
2004
-
Small molecules that induce cardiomyogenesis in embryonic stem cells.
126:1590-1591.
2004
-
Steric and magnetic asymmetry distinguished by encapsulation.
126:6216-6217.
2004
-
Studies toward diazonamide A: Development of a hetero-pinacol macrocyclization cascade for the construction of the bis-macrocyclic framework of the originally proposed structure.
126:10174-10182.
2004
-
Studies toward diazonamide A: Initial synthetic forays directed toward the originally proposed structure.
126:10162-10173.
2004
-
Total synthesis and examination of three key analogues of ramoplanin: a lipoglycodepsipeptide with potent antibiotic activity.
126:1041-1043.
2004
-
Total synthesis of formamicin.
126:9307-9317.
2004
-
Total synthesis of hamigerans and analogues thereof. Photochemical generation and diels-alder trapping of hydroxy-o-quinodimethanes.
126:613-627.
2004
-
Total synthesis of hybocarpone and analogues thereof. A facile dimerization of naphthazarins to pentacyclic systems.
126:607-612.
2004
-
Total synthesis of the ristocetin aglycon.
126:4310-4317.
2004
-
Total synthesis, structure revision, and absolute configuration of (+)-yatakemycin.
126:8396-8398.
2004
-
Toward assessing the position-dependent contributions of backbone hydrogen bonding to β-sheet folding thermodynamics employing amide-to-ester perturbations.
126:16762-16771.
2004
-
o-Iodoxybenzoic acid (IBX) as a viable reagent in the manipulation of nitrogen- and sulfur-containing substrates: scope, generality, and mechanism of IBX-mediated amine oxidations and dithiane deprotections.
126:5192-5201.
2004
-
A bifunctional molecule that displays context-dependent cellular activity.
125:7575-7580.
2003
-
A copper-catalyzed C-N bond formation involving sp-hybridized carbons. A direct entry to chiral ynamides via N-alkynylation of amides.
125:2368-2369.
2003
-
A selective irreversible inhibitor targeting a PDZ protein interaction domain.
125:12074-12075.
2003
-
An enantioselective synthesis of FR182877 provides a chemical rationalization of its structure and affords multigram quantities of its direct precursor.
125:5393-5407.
2003
-
Combined experimental/theoretical refinement of indole ring geometry using deuterium magnetic resonance and ab initio calculations.
125:12268-12276.
2003
-
Epothilone C macrolactonization and hydrolysis are catalyzed by the isolated thioesterase domain of epothilone polyketide synthase.
125:3428-3429.
2003
-
Mechanism of the glutathione transferase-catalyzed conversion of antitumor 2-crotonyloxymethyl-2-cycloalkenones to GSH adducts.
125:15049-15058.
2003
-
Novel selective inhibitors of the interaction of individual nuclear hormone receptors with a mutually shared steroid receptor coactivator 2.
125:6852-6853.
2003
-
Reversible switching of high-speed air-liquid two-phase flows using electrowetting-assisted flow-pattern change.
125:14678-14679.
2003
-
Self-assembly combining two bioactive peptide-amphiphile molecules into nanofibers by electrostatic attraction.
125:7146-7147.
2003
-
Spectroscopy and reactivity of a photogenerated tryptophan radical in a structurally defined protein environment.
125:14220-14221.
2003
-
Synthesis and activity of ruthenium alkylidene complexes coordinated with phosphine and N-heterocyclic carbene ligands.
125:2546-2558.
2003
-
Theoretical calculations of carbon-oxygen bond dissociation enthalpies of peroxyl radicals formed in the autoxidation of lipids.
125:5801-5810.
2003
-
Understanding the mechanism of H(+)-induced demetalation as a design strategy for robust iron(III) peroxide-activating catalysts.
125:12378-12379.
2003
-
A heterocyclic peptide nanotube.
125:9372-9376.
2003
-
A method for the generation of glycoprotein mimetics.
125:1702-1703.
2003
-
A mild, catalytic, and highly selective method for the oxidation of alpha,beta-enones to 1,4-enediones.
125:3232-3233.
2003
-
A new strategy for improved nicotine vaccines using conformationally constrained haptens.
125:7164-7165.
2003
-
A novel 4-methylideneimidazole-5-one-containing tyrosine aminomutase in enediyne antitumor antibiotic c-1027 biosynthesis.
125:6062-6063.
2003
-
A potent and highly selective inhibitor of human α-1,3-fucosyltransferase via click chemistry.
125:9588-9589.
2003
-
Activity-based protein profiling in vivo using a copper(i)-catalyzed azide-alkyne 3+2 cycloaddition.
125:4686-4687.
2003
-
Adding amino acids with novel reactivity to the genetic code of Saccharomyces cerevisiae.
125:11782-11783.
2003
-
Adsorption of beta-hairpin peptides on the surface of water: A neutron reflection study.
125:3751-3757.
2003
-
Alkane C-H activation and catalysis by an O-donor ligated iridium complex.
125:14292-14293.
2003
-
Application of NMR SHAPES screening to an RNA target.
125:15724-15725.
2003
-
Assembly of resorcinarene capsules in wet solvents.
125:3432-3433.
2003
-
Asymmetric environments in encapsulation complexes.
125:6239-6243.
2003
-
Bioconjugation by copper(I)-catalyzed azide-alkyne [3 + 2] cycloaddition.
125:3192-3193.
2003
-
Catalysis of the photo-Fries reaction: Antibody-mediated stabilization of high energy states.
125:15395-15401.
2003
-
DNA alkylation properties of yatakemycin.
125:10971-10976.
2003
-
DNA detection and signal amplification via an engineered allosteric enzyme.
125:344-345.
2003
-
DNA-based photonic logic gates: AND, NAND, and INHIBIT.
125:346-347.
2003
-
Density functional and reduction potential calculations of Fe4S4 clusters.
125:1923-1936.
2003
-
Determinants of unnatural nucleobase stability and polymerase recognition.
125:9638-9646.
2003
-
Experimental determination of the absolute enantioselectivity of an anti body-catalyzed Diels-Alder reaction and theoretical explorations of the origins of stereoselectivity.
125:2489-2506.
2003
-
Fabrication of assembled virus nanostructures on templates of chemoselective linkers formed by scanning probe nanolithography.
125:6848-6849.
2003
-
Fluorescent detection of carbon-carbon bond formation.
125:8523-8528.
2003
-
Fundamental role of the fostriecin unsaturated lactone and implications for selective protein phosphatase inhibition.
125:15694-15695.
2003
-
Generation of a bacterium with a 21 amino acid genetic code.
125:935-939.
2003
-
Hybridization-based unquenching of DNA hairpins on au surfaces: prototypical "molecular beacon" biosensors.
125:4012-4013.
2003
-
Individual solvent/solute interactions through social isomerism.
125:13981-13983.
2003
-
Insights into the origin of high activity and stability of catalysts derived from bulky, electron-rich monophosphinobiaryl ligands in the Pd-catalyzed C-N bond formation.
125:13978-13980.
2003
-
Isolation of protein ligands from large peptoid libraries.
125:13995-14004.
2003
-
Kinetic evidence for a tetrameric transition state in the asymmetric autocatalytic alkylation of pyrimidyl aldehydes.
125:8978-8979.
2003
-
Mixed-element capture agents: A simple strategy for the construction of synthetic, high-affinity protein capture ligands.
125:9550-9551.
2003
-
Partitioning the loss in vancomycin binding affinity for D-Ala-D-Lac into lost H-bond and repulsive lone pair contributions.
125:9314-9315.
2003
-
Photoisomerization and proton transfer in photoactive yellow protein.
125:8186-8194.
2003
-
Reactivity and molecular recognition: Amine methylation by an introverted ester.
125:14682-14683.
2003
-
Short, enantioselective total synthesis of okaramine n.
125:5628-5629.
2003
-
Site-specific incorporation of a redox-active amino acid into proteins.
125:14662-14663.
2003
-
Small-molecule switches for zinc finger transcription factors.
125:612-613.
2003
-
Structural, spectroscopic, and redox consequences of central ligand in the FeMoco of nitrogenase: a density functional theoretical study.
125:8377-8383.
2003
-
Structure of antibacterial peptide microcin J25: a 21-residue lariat protoknot.
125:12382-12383.
2003
-
Symmetry and bonding in metalloporphyrins. A modern implementation for the bonding analyses of five- and six-coordinate high-spin iron(III)-porphyrin complexes through density functional calculation and NMR spectroscopy.
125:6774-6783.
2003
-
Synthesis and characterization of potent bivalent amyloidosis inhibitors that bind prior to transthyretin tetramerization.
125:13404-13414.
2003
-
The effect of minor-groove hydrogen-bond acceptors and donors on the stability and replication of four unnatural base pairs.
125:6134-6139.
2003
-
Theoretical examination of Mg(2+)-mediated hydrolysis of a phosphodiester linkage as proposed for the hammerhead ribozyme.
125:9861-9867.
2003
-
Total synthesis of apoptolidin: Completion of the synthesis and analogue synthesis and evaluation.
125:15443-15454.
2003
-
Total synthesis of apoptolidin: Construction of enantiomerically pure fragments.
125:15433-15442.
2003
-
Total synthesis of the ramoplanin a2 and ramoplanose aglycon.
125:1877-1887.
2003
-
Why is tetrazole formation by addition of azide to organic nitriles catalyzed by zinc(II) salts?.
125:9983-9987.
2003
-
A synthesis of (+)-FR182877, featuring tandem transannular Diels-Alder reactions inspired by a postulated biogenesis.
124:4552-4553.
2002
-
An enzyme library approach to biocatalysis: development of nitrilases for enantioselective production of carboxylic acid derivatives.
124:9024-9025.
2002
-
Callipeltoside A: total synthesis, assignment of the absolute and relative configuration, and evaluation of synthetic analogues.
124:10396-10415.
2002
-
Contribution of aromatic interactions to alpha-helix stability.
124:9751-9755.
2002
-
Design of three-dimensional, millimeter-scale models for molecular folding.
124:18-19.
2002
-
Membraneless vanadium redox fuel cell using laminar flow.
124:12930-12931.
2002
-
Ruthenium-mediated cycloaromatization of acyclic enediynes and dienynes at ambient temperature.
124:3506-3507.
2002
-
Template-directed self-assembly of 10-mu m-sized hexagonal plates.
124:5419-5426.
2002
-
A combinatorial scaffold approach toward kinase-directed heterocycle libraries.
124:1594-1596.
2002
-
A highly enantioselective amino acid-catalyzed route to functionalized alpha-amino acids.
124:1842-1843.
2002
-
A highly enantioselective route to either enantiomer of both alpha- and beta-amino acid derivatives.
124:1866-1867.
2002
-
A modular assembly strategy for improving the substrate specificity of small catalytic peptides.
124:3510-3511.
2002
-
A novel silver(I)-mediated DNA base pair.
124:13684-13685.
2002
-
A parallel approach to the discovery of carrier delivery vehicles to enhance antigen immunogenicity.
124:4946-4947.
2002
-
A potent and highly selective sulfotransferase inhibitor.
124:14524-14525.
2002
-
A short synthetic route to (+)-austamide, (+)-deoxyisoaustamide, and (+)-hydratoaustamide from a common precursor by a novel palladium-mediated indole -> dihydroindoloazocine cyclization.
124:7904-7905.
2002
-
A small molecule with osteogenesis-inducing activity in multipotent mesenchymal progenitor cells.
124:14520-14521.
2002
-
A structural model for the high-valent intermediate Q of methane monooxygenase from broken-symmetry density functional and electrostatics calculations.
124:5890-5894.
2002
-
A synthetic receptor for choline and carnitine.
124:14014-14016.
2002
-
Adding L-3-(2-naphthyl)alanine to the genetic code of E. coli.
124:1836-1837.
2002
-
Addition of p-azido-L-phenylaianine to the genetic code of Escherichia coli.
124:9026-9027.
2002
-
An NMR study of the rates of single-molecule exchange in a cylindrical host capsule.
124:8780-8781.
2002
-
Aqueous aldol catalysis by a nicotine metabolite.
124:3220-3221.
2002
-
Atropselective macrocyclization of diaryl ether ring systems: Application to the synthesis of vancomycin model systems.
124:10451-10455.
2002
-
Binding modes for the first coupled electron and proton addition to FeMoco of nitrogenase.
124:4546-4547.
2002
-
Cell-wall engineering of living bacteria.
124:9018-9019.
2002
-
Crystal structure of a B-form DNA duplex containing (L)-alpha-threofuranosyl (3 '-> 2 ') nucleosides: A four-carbon sugar is easily accommodated into the backbone of DNA.
124:13716-13721.
2002
-
Density functional study of the mechanism of a tyrosine phosphatase: I. Intermediate formation.
124:10225-10235.
2002
-
Efficient chemoenzymatic synthesis of o-linked sialyl oligosaccharides.
124:5739-5746.
2002
-
Enantioselective synthesis of 1,5-anti- and 1,5-syn-diols using a highly diastereoselective one-pot double allylboration reaction sequence.
124:13644-13645.
2002
-
Enzymatic phosphorylation of unnatural nucleosides.
124:14626-14630.
2002
-
Erythropoietin mimetics derived from solution phase combinatorial libraries.
124:544-555.
2002
-
Extending synthetic access to proteins with a removable acyl transfer auxiliary.
124:4642-4646.
2002
-
Fluorescent probes for cytochrome p450 structural characterization and inhibitor screening.
124:10254-10255.
2002
-
Hairpin versus extended DNA binding of a substituted beta-alanine linked polyamide.
124:2148-2152.
2002
-
Intramolecular Diels-Alder and tandem intramolecular Diels-Alder/1,3-dipolar cycloaddition reactions of 1,3,4-oxadiazoles.
124:11292-11294.
2002
-
Iodine(V) reagents in organic synthesis. Part 1. Synthesis of polycyclic heterocycles via Dess-Martin periodinane-mediated cascade cyclization: Generality, scope, and mechanism of the reaction.
124:2212-2220.
2002
-
Iodine(V) reagents in organic synthesis. Part 2. Access to complex molecular architectures via Dess-Martin periodinane-generated o-imidoquinones.
124:2221-2232.
2002
-
Iodine(V) reagents in organic synthesis. Part 3. New routes to heterocyclic compounds via o-iodoxybenzoic acid-mediated cyclizations: Generality, scope, and mechanism.
124:2233-2244.
2002
-
Iodine(V) reagents in organic synthesis. Part 4. O-iodoxybenzoic acid as a chemospecific tool for single electron transfer-based oxidation processes.
124:2245-2258.
2002
-
Magnetic resonance imaging detects a specific peptide-protein binding event.
124:3514-3515.
2002
-
Mechanisms of tetrazole formation by addition of azide to nitriles.
124:12210-12216.
2002
-
Mechanistic insights into the Pd(BINAP)-catalyzed amination of aryl bromides: kinetic studies under synthetically relevant conditions.
124:14104-14114.
2002
-
Metal-switching and self-inclusion of functional cavitands.
124:10349-10358.
2002
-
Modulating ion channel properties of transmembrane peptide nanotubes through heteromeric supramolecular assemblies.
124:10004-10005.
2002
-
Novel chemistry of alpha-tosyloxy ketones: Applications to the solution- and solid-phase synthesis of privileged heterocycle and enediyne libraries.
124:5718-5728.
2002
-
Phage-display selection of a human single-chain fv antibody highly specific for melanoma and breast cancer cells using a chemoenzymatically synthesized G(M3)-carbohydrate antigen.
124:12439-12446.
2002
-
Protein dynamics and cytochrome c: Correlations between ligand vibrations and redox activity.
124:1846-1847.
2002
-
RNA-cleaving DNA enzymes with altered regio- or enantioselectivity.
124:12499-12506.
2002
-
Rationalization of anomalous nonlinear effects in the alkylation of substituted benzaldehydes.
124:13652-13653.
2002
-
Social isomers in encapsulation complexes.
124:12074-12075.
2002
-
Solid-phase synthesis of oligosaccharides and on-resin quantitative monitoring using gated decoupling c-13 NMR.
124:3591-3599.
2002
-
Solution NMR techniques for large molecular and supramolecular structures.
124:12144-12153.
2002
-
Solution-phase parallel synthesis of a pharmacophore library of hun-7293 analogues: a general chemical mutagenesis approach to defining structure-function properties of naturally occurring cyclic (depsi)peptides.
124:5431-5440.
2002
-
Stability and selectivity of unnatural DNA with five-membered-ring nucleobase analogues.
124:1222-1226.
2002
-
Structural chemistry of a green fluorescent protein zn biosensor.
124:3522-3524.
2002
-
Synthesis and DNA binding properties of iminodiacetic acid-linked polyamides: characterization of cooperative extended 2 : 1 side-by-side parallel binding.
124:10676-10682.
2002
-
Synthesis of a negatively charged dibenzofuran-based beta-turn mimetic and its incorporation into the WW miniprotein-enhanced solubility without a loss of thermodynamic stability.
124:11900-11907.
2002
-
Synthesis of sugar arrays in microtiter plate.
124:14397-14402.
2002
-
Synthesis, properties, and reactivity of cocaine benzoylthio ester possessing the cocaine absolute configuration.
124:3661-3668.
2002
-
The chemistry of amine-azide interconversion: Catalytic diazotransfer and regioselective azide reduction.
124:10773-10778.
2002
-
The effect of backbone cyclization on the thermodynamics of beta-sheet unfolding: Stability optimization of the PINWW domain.
124:4980-4986.
2002
-
The origin of diastereofacial control in allylboration reactions using tartrate ester derived allylboronates: attractive interactions between the Lewis acid coordinated aldehyde carbonyl group and an ester carbonyl oxygen.
124:10692-10697.
2002
-
The synthesis and biological characterization of a ceramide library.
124:1856-1857.
2002
-
The vinylogous intramolecular Morita-Baylis-Hillman reaction: synthesis of functionalized cyclopentenes and cyclohexenes with trialkylphosphines as nucleophilic catalysts.
124:2404-2405.
2002
-
Total synthesis of (-)-bafilomycin A(1).
124:6981-6990.
2002
-
Total synthesis of the CP-molecules (CP-263,114 and CP-225,917, phomoidrides B and A). 1. Racemic and asymmetric synthesis of bicyclo 4.3.1 key building blocks.
124:2183-2189.
2002
-
Total synthesis of the CP-molecules (CP-263,114 and CP-225,917, phomoidrides B and A). 2. Model studies for the construction of key structural elements and first-generation strategy.
124:2190-2201.
2002
-
Total synthesis of the CP-molecules (CP-263,114 and CP-225,917, phomoidrides B and A). 3. Completion and synthesis of advanced analogues.
124:2202-2211.
2002
-
Total synthesis of the ramoplanin a2 and ramoplanose aglycon.
124:5288-5290.
2002
-
Toward synthetic transcription activators: Recruitment of transcription factors to DNA by a pna-peptide chimera.
124:1838-1839.
2002
-
Tppt(iv)me(h)(2) forms a sigma-ch4 complex that is kinetically resistant to methane liberation.
124:3226-3228.
2002
-
Tpptme(h)(2): Why is there h/d scrambling of the methyl group but not methane loss?.
124:7041-7054.
2002
-
Water-stabilized cavitands.
124:2854-2855.
2002
-
An inhibitor of the interaction of thyroid hormone receptor beta and glucocorticoid interacting protein 1.
123:1525-1526.
2001
-
Chromatographic purification of soluble single-walled carbon nanotubes (s-SWNTs).
123:733-734.
2001
-
Concise asymmetric syntheses of radicicol and monocillin I.
123:10903-10908.
2001
-
Conformational analysis of a flexible oligosaccharide using residual dipolar couplings.
123:485-492.
2001
-
Electron tunneling in single crystals of Pseudomonas aeruginosa azurins.
123:11623-11631.
2001
-
Properties of photogenerated tryptophan and tyrosyl radicals in structurally characterized proteins containing rhenium(I) tricarbonyl diimines.
123:3181-3182.
2001
-
Self-assembly of 10-mu m-sized objects into ordered three-dimensional arrays.
123:7677-7682.
2001
-
Substrate recognition and selection by the initiation module PheATE of gramicidin S synthetase.
123:11208-11218.
2001
-
Three-dimensional self-assembly of complex, millimeter-scale structures through capillary bonding.
123:8119-8120.
2001
-
Total synthesis of deschlorocallipeltoside A.
123:9449-9450.
2001
-
"Flexiball" toolkit: A modular approach to self-assembling capsules.
123:11519-11533.
2001
-
A de novo designed peptide ligase: A mechanistic investigation.
123:1797-1803.
2001
-
A self-folding metallocavitand.
123:9929-9934.
2001
-
A simple, high-resolution method for establishing DNA binding affinity and sequence selectivity.
123:5878-5891.
2001
-
Amino acid catalyzed direct asymmetric aldol reactions: A bioorganic approach to catalytic asymmetric carbon-carbon bond-forming reactions.
123:5260-5267.
2001
-
An efficient chemoenzymatic strategy for the synthesis of wild-type and vancomycin-resistant bacterial cell-wall precursors: UDP-N-acetylmuramyl-peptides.
123:9916-9917.
2001
-
Asymmetric total synthesis of ent-(-)-roseophilin: Assignment of absolute configuration.
123:8515-8519.
2001
-
C-13,c-13 - and c-13,h-1 -trosy in a triple resonance experiment for ribose-base and intrabase correlations in nucleic acids.
123:658-664.
2001
-
Cavitand-porphyrins.
123:4659-4669.
2001
-
Chemical synthesis and biological evaluation of cis- and trans-12,13-cyclopropyl and 12,13-cyclobutyl epothilones and related pyridine side chain analogues.
123:9313-9323.
2001
-
Chiral softballs: Synthesis and molecular recognition properties.
123:5213-5220.
2001
-
Cloning and heterologous expression of the macrotetrolide biosynthetic gene cluster revealed a novel polyketide synthase that lacks an acyl carrier protein.
123:3385-3386.
2001
-
Complete thermodynamic characterization of reduction and protonation of the bc(1)-type rieske 2fe-2s center of thermus thermophilus.
123:9906-9907.
2001
-
Conversion of enediynes into quinones by antibody catalysis and in aqueous buffers: Implications for an alternative enediynes therapeutic mechanism.
123:3607-3608.
2001
-
Design of allele-specific protein methyltransferase inhibitors.
123:11608-11613.
2001
-
Direct observation of protein vibrations by selective incorporation of spectroscopically observable carbon-deuterium bonds in cytochrome c.
123:2426-2427.
2001
-
Efforts toward expansion of the genetic alphabet: replication of DNA with three base pairs.
123:7439-7440.
2001
-
FeMo cofactor of nitrogenase: a density functional study of states M(N), M(OX), M(R), and M(I).
123:12392-12410.
2001
-
First and second generation total synthesis of the teicoplanin aglycon.
123:1862-1871.
2001
-
High-temperature protein mass mapping using a thermophilic protease.
123:1774-1775.
2001
-
Identification of a novel class of small-molecule antiangiogenic agents through the screening of combinatorial libraries which function by inhibiting the binding and localization of proteinase MMP2 to integrin alpha(V)beta(3).
123:1280-1288.
2001
-
Incorporating beta-turns and a turn mimetic out of context in loop 1 of the WW domain affords cooperatively folded beta-sheets.
123:5206-5212.
2001
-
Kinetic resolution using enantioimpure catalysts: mechanistic considerations of complex rate laws.
123:545-553.
2001
-
Kinetic studies of heck coupling reactions using palladacycle catalysts: Experimental and kinetic modeling of the role of dimer species.
123:1848-1855.
2001
-
Medium-dependent self-assembly of an amphiphilic peptide: Direct observation of peptide phase domains at the air-water interface.
123:775-776.
2001
-
Metal cation complexation and activation of reversed CPyi analogues of CC-1065 and duocarmycin SA: Partitioning the effects of binding and catalysis.
123:9299-9306.
2001
-
Microbial glycosyltransferases for carbohydrate synthesis: Alpha-2,3-sialyltransferase from neisseria gonorrheae.
123:10909-10918.
2001
-
Modulating artificial membrane morphology: Ph-induced chromatic transition and nanostructural transformation of a bolaamphiphilic conjugated polymer from blue helical ribbons to red nanofibers.
123:3205-3213.
2001
-
Monitoring the conformational fluctuations of DNA hairpins using single-pair fluorescence resonance energy transfer.
123:4295-4303.
2001
-
Observation of unusual kinetics in Heck reactions of aryl halides: the role of non-steady-state catalyst concentration.
123:4621-4622.
2001
-
Origins of asymmetric amplification in autocatalytic alkylzinc additions.
123:10103-10104.
2001
-
Residual dipolar coupling TOCSY for direct through space correlations of base protons and phosphorus nuclei in RNA.
123:3395-3396.
2001
-
Selective oxidation at carbon adjacent to aromatic systems with IBX.
123:3183-3185.
2001
-
Sequence-dependent correction of random coil NMR chemical shifts.
123:2970-2978.
2001
-
Structure of a copper-mediated base pair in DNA.
123:12364-12367.
2001
-
Synthesis and catalytic antibody functionalization of dendrimers.
123:8248-8259.
2001
-
Synthesis of peptides and proteins without cysteine residues by native chemical ligation combined with desulfurization.
123:526-533.
2001
-
Tautomerization dynamics of a model base pair in DNA.
123:4613-4614.
2001
-
Total syntheses of thiocoraline and be-22179 and assessment of their DNA binding and biological properties.
123:561-568.
2001
-
Total synthesis of fostriecin (CI-920).
123:4161-4167.
2001
-
A concise synthesis of (-)-hispidospermidin guided by a postulated biogenesis.
122:9556-9557.
2000
-
Carbene complexes in the synthesis of complex natural products: total synthesis of the calphostins.
122:3224-3225.
2000
-
Molecular dynamics simulations of nucleic acids with a generalized born solvation model.
122:2489-2498.
2000
-
RNA Diels-Alderases: relationships between unique sequences and catalytic function.
122:1015-1021.
2000
-
Surveying for surfaces that resist the adsorption of proteins.
122:8303-8304.
2000
-
A highly efficient method for site-specific modification of unprotected peptides after chemical synthesis.
122:3567-3573.
2000
-
A highly stereoselective synthesis of the landomycin A hexasaccharide unit.
122:6124-6125.
2000
-
A new functional suppressor tRNA/aminoacyl-tRNA synthetase pair for the in vivo incorporation of unnatural amino acids into proteins.
122:5010-5011.
2000
-
A new method for the one-step synthesis of alpha,beta-unsaturated carbonyl systems from saturated alcohols and carbonyl compounds.
122:7596-7597.
2000
-
A new method of in situ activation for a novel class of DNA alkylating agents: tunable metal cation complexation and activation.
122:6325-6326.
2000
-
A novel copper-mediated DNA base pair.
122:10714-10715.
2000
-
A novel strategy for the solid-phase synthesis of substituted indolines.
122:2966-2967.
2000
-
A phototautomerizable model DNA base pair.
122:9917-9920.
2000
-
Anti-markovnikov olefin arylation catalyzed by an iridium complex.
122:7414-7415.
2000
-
Antibodies mimic natural oxidosqualene-cyclase action in steroid ring a formation.
122:40-45.
2000
-
Antibody-catalysis of a bimolecular asymmetric 1,3-dipolar cycloaddition reaction.
122:3244-3245.
2000
-
Biomimetic total synthesis of bisorbicillinol, bisorbibutenolide, trichodimerol, and designed analogues of the bisorbicillinoids.
122:3071-3079.
2000
-
Chemically reactive immunogens lead to functional convergence of the immune response.
122:10743-10753.
2000
-
Chemoenzymatic synthesis of a PSGL-1 N-terminal glycopeptide containing tyrosine sulfate and α-O-linked sialyl Lewis X.
122:4241-4242.
2000
-
Chiral space in a unimolecular capsule.
122:7811-7812.
2000
-
Cyclic peptides as molecular adapters for a pore-forming protein.
122:11757-11766.
2000
-
Design of bifunctional antibiotics that target bacterial rRNA and inhibit resistance-causing enzymes.
122:5230-5231.
2000
-
Design, synthesis, and characterization of 4-ester CI2, a model for backbone hydrogen bonding in protein α-helices.
122:12079-12082.
2000
-
Detection and mechanistic studies of multicomponent assembly by fluorescence resonance energy transfer.
122:7876-7882.
2000
-
Diversity and selection in self-assembled tetrameric capsules.
122:4251-4252.
2000
-
Efforts toward expansion of the genetic alphabet: optimization of interbase hydrophobic interactions.
122:7621-7632.
2000
-
Efforts toward the expansion of the genetic alphabet: information storage and replication with unnatural hydrophobic base pairs.
122:3274-3287.
2000
-
Emergent conformational preferences of a self-assembling small molecule: Structure and dynamics in a tetrameric capsule.
122:10991-10996.
2000
-
Expanded calix[4]arene tetraurea capsules.
122:9868-9869.
2000
-
Highly enantioselective palladium(ii)-catalyzed cyclization of (z)-4 '-acetoxy-2 '-butenyl 2-alkynoates: An efficient synthesis of optically active gamma-butyrolactones.
122:7604-7605.
2000
-
Intein-mediated synthesis of proteins containing carbohydrates and other molecular probes.
122:5421-5428.
2000
-
Natural product-like combinatorial libraries based on privileged structures. 1. General principles and solid-phase synthesis of benzopyrans.
122:9939-9953.
2000
-
Natural product-like combinatorial libraries based on privileged structures. 2. Construction of a 10 000-membered benzopyran library by directed split-and-pool chemistry using nanokans and optical encoding.
122:9954-9967.
2000
-
Natural product-like combinatorial libraries based on privileged structures. 3. The "libraries from libraries" principle for diversity enhancement of benzopyran libraries.
122:9968-9976.
2000
-
New molecular vessels: Synthesis and chiroselective recognition.
122:9628-9630.
2000
-
Nmr assignment and secondary structure determination of an octameric 110 kda protein using trosy in triple resonance experiments.
122:7543-7548.
2000
-
Novel solution- and solid-phase chemistry of α-sulfonated ketones applicable to combinatorial chemistry.
122:10246-10248.
2000
-
Polymer-supported (Salen)Mn catalysts for asymmetric epoxidation: A comparison between soluble and insoluble matrices.
122:6929-6934.
2000
-
Proline-catalyzed direct asymmetric aldol reactions.
122:2395-2396.
2000
-
Protofilaments, filaments, ribbons, and fibrils from peptidomimetic self-assembly: Implications for amyloid fibril formation and materials science.
122:5262-5277.
2000
-
RNA cleavage by a DNA enzyme with extended chemical functionality.
122:2433-2439.
2000
-
Rational design of an unnatural base pair with increased kinetic selectivity.
122:8803-8804.
2000
-
Reconstructing aldolase antibodies to alter their substrate specificity and turnover.
122:4835-4836.
2000
-
Self-folding cavitands of nanoscale dimensions.
122:8880-8889.
2000
-
Structural basis for BABIM inhibition of botulinum neurotoxin type B protease.
122:11268-11269.
2000
-
Structure-based design of N-phenyl phenoxazine transthyretin amyloid fibril inhibitors.
122:2178-2192.
2000
-
Synthesis and assembly of self-complementary cavitands.
122:4573-4582.
2000
-
Thermal atropisomerism of teicoplanin aglycon derivatives: Preparation of the P,P,P and M,P,P atropisomers of the teicoplanin aglycon via selective equilibration of the DE ring system.
122:10047-10055.
2000
-
Titanium and zirconium et2c2b4h4-metal-phosphine complexes: Synthesis, characterization, and ethylene polymerization activity.
122:10573-10580.
2000
-
Total syntheses of thiocoraline and be-22179: Establishment of relative and absolute stereochemistry.
122:2956-2957.
2000
-
Total synthesis of distamycin A and 2640 analogues: A solution-phase combinatorial approach to the discovery of new, bioactive DNA binding agents and development of a rapid, high-throughput screen for determining relative DNA binding affinity or DNA binding sequence selectivity.
122:6382-6394.
2000
-
Total synthesis of the novel immunosuppressant sanglifehrin a.
122:3830-3838.
2000
-
Total synthesis of the rubrolone aglycon.
122:12169-12173.
2000
-
Total synthesis of the teicoplanin aglycon.
122:7416-7417.
2000
-
Tyrosine sulfation on a psgl-1 glycopeptide influences the reactivity of glycosyltransferases responsible for synthesis of the attached o-glycan.
122:742-743.
2000
-
Affinity and specificity of multiple hydroxypyrrole/pyrrole ring pairings for coded recognition of DNA.
121:260-261.
1999
-
Characteristics of an RNA Diels-Alderase active site.
121:3614-3617.
1999
-
Cycle polyamide motif for recognition of the minor groove of DNA.
121:1121-1129.
1999
-
First synthesis of a bidesmosidic triterpene saponin by a highly efficient procedure.
121:12196-12197.
1999
-
Printing small molecules as microarrays and detecting protein-ligand interactions en masse.
121:7967-7968.
1999
-
Proton-transfer polymerization: A new approach to hyperbranched polymers.
121:2313-2314.
1999
-
Sequence selectivity of 3-hydroxypyrrole/pyrrole ring pairings in the DNA minor groove.
121:11621-11629.
1999
-
The allyl leaving group approach to tricoordinate silyl, germyl, and stannyl cations.
121:5001-5008.
1999
-
A catalytic enantioselective route to hydroxy-substituted quaternary carbon centers: Resolution of tertiary aldols with a catalytic antibody.
121:7283-7291.
1999
-
A highly stereoselective synthesis of 2-deoxy-beta-glycosides using 2-deoxy-2-iodo-glucopyranosyl acetate donors.
121:3541-3542.
1999
-
A model for hydride transfer in thymidylate synthase based on unnatural amino acid mutagenesis.
121:7965-7966.
1999
-
Antibody-metalloporphyrin catalytic assembly mimics natural oxidation enzymes.
121:8978-8982.
1999
-
Binding-induced activation of DNA alkylation by duocarmycin SA: Insights from the structure of an indole derivative-DNA adduct.
121:5645-5652.
1999
-
C-13 NMR flux ratio analysis of escherichia coli central carbon metabolism in microaerobic bioprocesses.
121:1407-1408.
1999
-
Catalytically distinct antibodies prepared by the reactive immunization versus transition state analogue hapten manifolds.
121:10461-10467.
1999
-
Characterization of self-assembling encapsulation complexes in the gas phase and solution.
121:2133-2138.
1999
-
Chiral microenvironments in self-assembled capsules.
121:10281-10285.
1999
-
Conformationally assisted protein ligation using C-terminal thioester peptides.
121:6332-6333.
1999
-
Crystalline cyclic peptide nanotubes at interfaces.
121:1186-1191.
1999
-
De novo design of protein function: Predictable structure-function relationships in synthetic redox proteins.
121:858-859.
1999
-
Design and synthesis of new aminoglycoside antibiotics containing neamine as an optimal core structure: Correlation of antibiotic activity with in vitro inhibition of translation.
121:6527-6541.
1999
-
Development of a new type of protease inhibitors, efficacious against FIV and HIV variants.
121:1145-1155.
1999
-
Diastereoselective total synthesis of the vancomycin aglycon with ordered atropisomer equilibrations.
121:3226-3227.
1999
-
Efforts toward expansion of the genetic alphabet: DNA polymerase recognition of a highly stable, self-fairing hydrophobic base.
121:11585-11586.
1999
-
Encapsulation of ion-molecule complexes: Second-sphere supramolecular chemistry.
121:7455-7456.
1999
-
Investigating molecular recognition by mass spectrometry: Characterization of calixarene-based self-assembling capsule hosts with charged guests.
121:4568-4579.
1999
-
Kinetically stable caviplexes in water.
121:11253-11254.
1999
-
Lipoic acid biosynthesis: Lipa is an iron-sulfur protein.
121:4706-4707.
1999
-
Nitrogen-halogen intermolecular forces in solution.
121:7973-7974.
1999
-
Photoinduced protein cross-linking mediated by palladium porphyrins.
121:11896-11897.
1999
-
Programmable one-pot oligosaccharide synthesis.
121:734-753.
1999
-
Selection of human metalloantibodies from a combinatorial phage single-chain antibody library.
121:6517-6518.
1999
-
Selective antibody-catalyzed solvolysis of endo-2-norbornyl mesylate.
121:10227-10228.
1999
-
Self-assembling peptidomimetic monolayer nucleates oriented CdS nanocrystals.
121:7266-7267.
1999
-
Self-complementary cavitands.
121:7459-7460.
1999
-
Signaling of escherichia coli enterotoxin on supramolecular redox bilayer vesicles.
121:6767-6768.
1999
-
Stereochemical relationships between encapsulated molecules.
121:4928-4929.
1999
-
Structural dynamics in the guanylate cyclase heme pocket after co photolysis.
121:7397-7400.
1999
-
Structural study on O-glycopeptides: Glycosylation-induced conformational changes of O-GlcNAc, O-LacNAc, O-Sialyl-LacNAc, and O-Sialyl-Lewis-X peptides of the mucin domain of madcam-1.
121:2409-2417.
1999
-
Synthesis of the fully functionalized bicyclic core of garsubellin A.
121:4724-4725.
1999
-
Total syntheses of ningalin A, lamellarin O, lukianol A, and permethyl storniamide A utilizing heterocyclic azadiene Diels-Alder reactions.
121:54-62.
1999
-
Total synthesis and comparative evaluation of luzopeptin A-C and quinoxapeptin A-C.
121:11375-11383.
1999
-
Total synthesis of HUN-7293.
121:6197-6205.
1999
-
Total synthesis of luzopeptins A-C.
121:1098-1099.
1999
-
Total synthesis of olivomycin A.
121:1990-1991.
1999
-
Total synthesis of phomazarin.
121:2471-2477.
1999
-
Total synthesis of the vancomycin aglycon.
121:10004-10011.
1999
-
Transfer of chiral information through molecular assembly.
121:11156-11163.
1999
-
Trosy-type triple-resonance experiments for sequential NMR assignments of large proteins.
121:844-848.
1999
-
Aliphatic/aromatic amino acid pairings for polyamide recognition in the minor groove of DNA.
120:6219-6226.
1998
-
Bispheric coordinative structuring in a zinc finger protein: NMR analysis of a point mutant of the carboxy terminal LIM domain of quail cysteine and glycine rich protein CRP2.
120:7127-7128.
1998
-
Synthesis of the first 2',6 bridged penams.
120:6846-6847.
1998
-
"Deep-cavity" resorcinarenes dimerize through hydrogen bonding and self-inclusion.
120:4977-4981.
1998
-
A library approach to the discovery of small molecules that recognize rna: Use of a 1,3-hydroxyamine motif as core.
120:8319-8327.
1998
-
A light-activated antibody catalyst.
120:12783-12790.
1998
-
A synthetic retrotransition (backward reading) sequence of the right-handed three-helix bundle domain (10-53) of protein a shows similarity in conformation as predicted by computation.
120:13042-13045.
1998
-
A systematic evaluation of the bleomycin A(2) L-threonine side chain: its role in preorganization of a compact conformation implicated in sequence-selective DNA cleavage.
120:9139-9148.
1998
-
Aldolase antibodies of remarkable scope.
120:2768-2779.
1998
-
Analysis of the role of the active site tyrosine in human glutathione transferase A1-1 by unnatural amino acid mutagenesis.
120:451-452.
1998
-
Assembly of oligosaccharide libraries with a designed building block and an efficient orthogonal protection-deprotection strategy.
120:7137-7138.
1998
-
Assessment of the role of the bleomycin A(2) pyrimidoblamic acid C4 amino group.
120:53-65.
1998
-
Bromine-catalyzed aziridination of olefins. A rare example of atom-transfer redox catalysis by a main group element.
120:6844-6845.
1998
-
Chiral capsules. 1. Softballs with asymmetric surfaces bind camphor derivatives.
120:66-69.
1998
-
Cofactor-induced refinement of catalytic antibody activity: A metal-specific allosteric effect.
120:2963-2964.
1998
-
Convergent functional groups: Intramolecular acyl transfer through a 34-membered ring.
120:5120-5121.
1998
-
Critical role of the linking amide in CC-1065 and the duocarmycins: implications on the source of DNA alkylation catalysis.
120:11554-11557.
1998
-
Cylindrical beta-sheet peptide assemblies.
120:8949-8962.
1998
-
Definition of the effect and role of the bleomycin A(2) valerate substituents: preorganization of a rigid, compact conformation implicated in sequence-selective DNA cleavage.
120:9149-9158.
1998
-
Diels-Alder reactions through reversible encapsulation.
120:3650-3656.
1998
-
Direct selection for catalysis from combinatorial antibody libraries using a boronic acid probe: Primary amide bond hydrolysis.
120:2211-2217.
1998
-
Dynamics of assembly and guest exchange in the tennis ball.
120:6193-6194.
1998
-
Enantioselective total synthesis of (-)-chlorothricolide via the tandem inter- and intramolecular Diels-Alder reaction of a hexaenoate intermediate.
120:7411-7419.
1998
-
Energetic analysis of an engineered cation-π interaction in Staphylococcal nuclease.
120:7135-7136.
1998
-
Formation of discrete, functional assemblies and informational polymers through the hydrogen-bonding preferences of calixarene aryl and sulfonyl tetraureas.
120:3657-3663.
1998
-
From styrenes to enantiopure alpha-arylglycines in two steps.
120:1207-1217.
1998
-
Glycosylation of threonine of the repeating unit of RNA polymerase II with beta-linked N-acetylglucosame leads to a turnlike structure.
120:11567-11575.
1998
-
Kinetic implications of nonlinear effects in asymmetric synthesis.
120:13349-13353.
1998
-
Macroporous p-type silicon fabry-perot layers. Fabrication, characterization, and applications in biosensing.
120:12108-12116.
1998
-
Measurement of deoxyribose (3)j(hh) scalar couplings reveals protein binding-induced changes in the sugar puckers of the DNA.
120:821-822.
1998
-
Mechanistic studies of an antibody-catalyzed elimination reaction.
120:5160-5167.
1998
-
Mechanistic studies of an antibody-catalyzed pericyclic rearrangement.
120:1945-1958.
1998
-
Multistep convergent solution-phase combinatorial synthesis and deletion synthesis deconvolution.
120:7220-7225.
1998
-
NMR studies of Co.deglycoBleomycin A2 green and its complex with d(CCAGGCCTGG).
120:2239-2250.
1998
-
Noncovalent assembly of microhelix recognition by a class II tRNA synthetase.
120:3269-3270.
1998
-
Oriented self-assembly of cyclic peptide nanotubes in lipid membranes.
120:4417-4424.
1998
-
Probing the specificity of aminoglycoside ribosomal rna interactions with designed synthetic analogs.
120:1965-1978.
1998
-
Rules of stereoselectivity in tandem oxidative polycyclization reaction with rhenium(vii) oxides.
120:9076-9077.
1998
-
Segmental isotope labeling for protein NMR using peptide splicing.
120:5591-5592.
1998
-
Self-assembled molecular capsule catalyzes a Diels-Alder reaction.
120:7389-7390.
1998
-
Self-assembling cyclic beta(3)-peptide nanotubes as artificial transmembrane ion channels.
120:651-656.
1998
-
Self-folding cavitands.
120:12216-12225.
1998
-
Snar cyclizations to form cyclic peptidomimetics of beta-turns.
120:10768-10769.
1998
-
Solid and solution phase synthesis and biological evaluation of combinatorial sarcodictyin libraries.
120:10814-10826.
1998
-
Solid phase synthesis of macrocycles by an intramolecular ketophosphonate reaction. Synthesis of a (dl)-muscone library.
120:5132-5133.
1998
-
Soluble supports tailored for organic synthesis: Parallel polymer synthesis via sequential normal/living free radical processes.
120:9481-9495.
1998
-
Solution structure of the complex between the head-to-tail dimer of calicheamicin gamma(i)(1) oligosaccharide and a DNA duplex containing d(acct) and d(tcct) high-affinity binding sites.
120:7183-7191.
1998
-
Solution- and solid-phase synthesis of n-protected glycopeptide esters of the benzyl type as substrates for subtilisin-catalyzed glycopeptide couplings.
120:1979-1989.
1998
-
Structural rules governing self-assembly emerge from new molecular capsules.
120:819-820.
1998
-
Structure of the michaelis complex of an efficient antibody acyl transferase determined by transferred nuclear overhauser enhancement spectroscopy.
120:7395-7396.
1998
-
Subtle functional interactions in the RNA minor groove at a nonessential base pair.
120:9110-9111.
1998
-
Synthesis and screening of linear and cyclic oligocarbamate libraries. Discovery of high affinity ligands for gpiib/iiia.
120:7706-7718.
1998
-
Thermal atropisomerism of aglucovancomycin derivatives: preparation of (M,M,M)- and (P,M,M)-aglucovancomycins.
120:8920-8926.
1998
-
Total synthesis of eleutherobin and eleuthosides A and B.
120:8674-8680.
1998
-
Total synthesis of goniocin and cyclogoniodenin t. Unique biosynthetic implications.
120:4017-4018.
1998
-
Total synthesis of mucocin.
120:11279-11284.
1998
-
Total synthesis of nothapodytine B and (-)-mappicine.
120:1218-1222.
1998
-
Total synthesis of sarcodictyins A and B.
120:8661-8673.
1998
-
Transverse relaxation-optimized spectroscopy (trosy) for NMR studies of aromatic spin systems in c-13-labeled proteins.
120:6394-6400.
1998
-
Trapping of the C5 methylene intermediate in thymidylate synthase.
120:449-450.
1998
-
Vinyl sulfonate esters and vinyl sulfonamides: potent, irreversible inhibitors of cysteine proteases.
120:10994-10995.
1998
-
An antibody-catalyzed selenoxide elimination.
119:3623-3624.
1997
-
Computational study of the role of solvation effects in reverse turn formation in the tetrapeptides APGD and APGN.
119:4964-4971.
1997
-
Deconvolution of combinatorial oligonucleotide libraries by electrospray ionization tandem mass spectrometry.
119:3861-3867.
1997
-
Recognition of seven base pair sequences in the minor groove of DNA by ten-ring pyrrole-imidazole polyamide hairpins.
119:7636-7644.
1997
-
Rhodium-catalyzed intramolecular silylformylation of alkenes.
119:12416-12417.
1997
-
Variation in strength of an unconventional C-H to O hydrogen bond in an engineered protein cavity.
119:9083-9084.
1997
-
3D 15N−13C−13C chemical shift correlation spectroscopy in rotating solids.
119:8540-8546.
1997
-
A general and highly efficient solid phase synthesis of oligosaccharides. Total synthesis of a heptasaccharide phytoalexin elicitor (HPE).
119:449-450.
1997
-
A new method for the synthesis of fluoro-carbohydrates and glycosides using selectfluor.
119:11743-11746.
1997
-
A pentacoordinate oxorhenium(V) metallochelate elicits antibody catalysts for phosphodiester cleavage.
119:4088-4089.
1997
-
A permutation test for stabilization of polypeptide helices by sequence-dependent side chain interactions: Characterization of a helix initiation site within the myohemerythrin sequence 76-87.
119:1153-1154.
1997
-
Analysis of backbone hydrogen bonding in a beta-turn of Staphylococcal nuclease.
119:12667-12668.
1997
-
Antibody catalysis of b(ac)2 aryl carbamate ester hydrolysis: A highly disfavored chemical process.
119:2315-2316.
1997
-
Antibody-catalyzed enantioselective robinson annulation.
119:8131-8132.
1997
-
Bis(trimethylsilyl) peroxide extends the range of oxorhenium catalysts for olefin epoxidation.
119:11536-11537.
1997
-
Chemoenzymatic preparation of novel cyclic imine sugars and rapid biological activity evaluation using electrospray mass spectrometry and kinetic analysis.
119:8146-8151.
1997
-
Chemoenzymatic solution- and solid-phase synthesis of o-glycopeptides of the mucin domain of madcam-1. A general route to o-lacnac, o-sialyl-lacnac, and o-sialyl-lewis-x peptides.
119:8766-8776.
1997
-
Chiral capsules: asymmetric binding in calixarene-based dimers.
119:12671-12672.
1997
-
Density functional study on the electronic structures of model peroxidase compounds I and II.
119:11442-11451.
1997
-
Deuterium relaxation in a uniformly n-15-labeled homeodomain and its DNA complex.
119:3842-3843.
1997
-
Diffusion-limited size-selective ion sensing based on sam-supported peptide nanotubes.
119:11306-11312.
1997
-
Direct observation of aminoglycoside-RNA interactions by surface plasmon resonance.
119:3641-3648.
1997
-
Duocarmycin SA shortened, simplified, and extended agents: A systematic examination of the role of the DNA binding subunit.
119:4977-4986.
1997
-
Enzymatic glycoprotein synthesis: Preparation of ribonuclease glycoforms via enzymatic glycopeptide condensation and glycosylation.
119:2114-2118.
1997
-
Enzymatic synthesis of beta-hydroxy-alpha-amino acids based on recombinant d- and l-threonine aldolases.
119:11734-11742.
1997
-
Experimental and theoretical kinetic isotope effects for asymmetric dihydroxylation. Evidence supporting a rate-limiting ''(3+2)'' cycloaddition.
119:9907-9908.
1997
-
Exploitation of subtilisin bpn' as catalyst for the synthesis of peptides containing noncoded amino acids, peptide mimetics and peptide conjugates.
119:3942-3947.
1997
-
First evidence that the mechanism of catalytic hydrogenation with homogeneous palladium and rhodium catalysts is strongly influenced by substrate polarity.
119:5257-5258.
1997
-
Formation of bridge-methylated decalins by antibody-catalyzed tandem cationic cyclization.
119:5993-5998.
1997
-
Highly efficient epoxidation of olefins using aqueous h2o2 and catalytic methyltrioxorhenium/pyridine: Pyridine-mediated ligand acceleration.
119:6189-6190.
1997
-
Highly efficient ring closure of aromatic dialdehydes to macrocyclic allenes.
119:3429-3433.
1997
-
Highly selective Lewis acid catalyzed Diels-Alder reactions of acyclic (Z)-1,3-dienes.
119:7402-7403.
1997
-
Influenza neuraminidase inhibitors possessing a novel hydrophobic interaction in the enzyme active site: Design, synthesis, and structural analysis of carbocyclic sialic acid analogues with potent anti-influenza activity.
119:681-690.
1997
-
Intramolecular hydrogen bonding controls the exchange rates of guests in a cavitand.
119:9911-9912.
1997
-
Mathematical models of nonlinear effects in asymmetric catalysis: new insights based on the role of reaction rate.
119:12934-12939.
1997
-
Measurement of (3)j(c2'p) scalar couplings in a 17 kda protein complex with c-13,n-15-labeled DNA distinguishes the b-i and b-ii phosphate conformations of the DNA.
119:9901-9902.
1997
-
Mechanism of inactivation of neuronal nitric oxide synthase by n-omega-allyl-l-arginine.
119:10888-10902.
1997
-
Methods for the chemical synthesis and readout of self-encoded arrays of polypeptide analogues.
119:7917-7927.
1997
-
Modulation of reactivity in native chemical ligation through the use of thiol additives.
119:4325-4329.
1997
-
Mutational analysis of backbone hydrogen bonds in Staphylococcal nuclease.
119:7151-7152.
1997
-
New synthetic technology for the construction of 9-membered ring cyclic ethers. Construction of the EFGH ring skeleton of brevetoxin a.
119:8105-8106.
1997
-
New synthetic technology for the stereocontrolled construction of 1,1'-disaccharides and 1,1':1'',2-trisaccharides. Synthesis of the fg ring system of everninomicin 13,384-1.
119:9057-9058.
1997
-
New synthetic technology for the synthesis of aryl ethers: Construction of c-o-d and d-o-e ring model systems of vancomycin.
119:3421-3422.
1997
-
Palladium-catalyzed functionalization of lactones via their cyclic ketene acetal phosphates. Efficient new synthetic technology for the construction of medium and large cyclic ethers.
119:5467-5468.
1997
-
Preparation of specifically deuterated and 13C-labeled RNA for NMR studies using enzymatic synthesis.
119:12100-12108.
1997
-
Reactive immunization strategy generates antibodies with high catalytic proficiencies.
119:10251-10252.
1997
-
Reversed and sandwiched analogs of duocarmycin SA: Establishment of the origin of the sequence-selective alkylation of DNA and new insights into the source of catalysis.
119:4987-4998.
1997
-
Ring inversion dynamics of encapsulated cyclohexane.
119:11701-11702.
1997
-
Small molecules as structural and functional mimics of sialyl Lewis X tetrasaccharide in selectin inhibition: A remarkable enhancement of inhibition by additional negative charge and/or hydrophobic group.
119:8152-8158.
1997
-
Synthesis and assembly of new molecular hosts: solvation and the energetics of encapsulation.
119:77-85.
1997
-
Synthesis and cation-mediated electronic interactions of two novel classes of porphyrin-fullerene hybrids.
119:8363-8364.
1997
-
Synthesis of prostaglandin E-2 methyl ester on a soluble-polymer support for the construction of prostanoid libraries.
119:8724-8725.
1997
-
Synthesis of the tricyclic core of eleutherobin and sarcodictyins and total synthesis of sarcodictyin a.
119:11353-11354.
1997
-
Tandem oxidative cyclization with rhenium oxide. Total synthesis of 17,18-bisepi-goniocin.
119:12014-12015.
1997
-
The olefin metathesis approach to epothilone a and its analogues.
119:7960-7973.
1997
-
Total syntheses of epothilones A and B via a macrolactonization-based strategy.
119:7974-7991.
1997
-
Total syntheses of epothilones a and b.
119:10073-10092.
1997
-
Total synthesis of (+)-damavaricin D.
119:11331-11332.
1997
-
Total synthesis of (+)-duocarmycin A, epi-(+)-duocarmycin A and their unnatural enantiomers: assessment of chemical and biological properties.
119:311-325.
1997
-
Toward an understanding of the high enantioselectivity in the osmium-catalyzed asymmetric dihydroxylation .4. Electronic effects in amine-accelerated osmylations.
119:1840-1858.
1997
-
X-ray absorption studies on the mixed-valence and fully reduced forms of the soluble cu-a domains of cytochrome c oxidase.
119:6135-6143.
1997
-
Electrostatic catalysis of the Claisen rearrangement: Probing the role of Glu78 in Bacillus subtilis chorismate mutase by genetic selection.
118:3069-3070.
1996
-
Extending the applicability of native chemical ligation.
118:5891-5896.
1996
-
(-)-Sandramycin: total synthesis and characterization of DNA binding properties.
118:1629-1644.
1996
-
A 2,3'-substituted biphenyl-based amino acid facilitates the formation of a monomeric beta-hairpin-like structure in aqueous solution at elevated temperature.
118:5836-5845.
1996
-
A new class of pentacoordinate ribonuclease inhibitors: Synthesis, characterization, and inhibition studies of ribonucleoside and anhydropentofuranose oxorhenium(V) complexes.
118:12521-12527.
1996
-
A nitroxyl synthase catalytic antibody.
118:3550-3555.
1996
-
A re-examination of pressure effects on enantioselectivity in asymmetric catalytic hydrogenation.
118:1348-1353.
1996
-
A re-examination of two linear pentapeptides claimed to be serine protease mimics.
118:8787-8790.
1996
-
A structure-based library approach to kinase inhibitors.
118:7430-7431.
1996
-
A template-induced incipient collagen-like triple-helical structure.
118:5156-5157.
1996
-
A weak calcium binding site in subtilisin BPN' has a dramatic effect on protein stability.
118:1645-1650.
1996
-
Acetyl-terminated and template-assembled collagen-based polypeptides composed of gly-pro-hyp sequences .2. Synthesis and conformational analysis by circular dichroism, ultraviolet absorbance, and optical rotation.
118:10351-10358.
1996
-
Acetyl-terminated and template-assembled collagen-based polypeptides composed of gly-pro-hyp sequences .3. Conformational analysis by h-1-NMR and molecular modeling studies.
118:10359-10364.
1996
-
An antibody-catalyzed 2,3-elimination reaction.
118:11686-11687.
1996
-
An antibody-catalyzed isomerization reaction.
118:3811-3817.
1996
-
An olefin metathesis based strategy for the construction of the JKL, OPQ, and UVW ring systems of maitotoxin.
118:10335-10336.
1996
-
Analysis of active site residues in Escherichia coli chorismate mutase by site-directed mutagenesis.
118:1789-1790.
1996
-
Antibodies with thiol-S-transferase activity.
118:5474-5475.
1996
-
Antibody catalyzed terpenoid cyclization.
118:11654-11655.
1996
-
Antibody-catalyzed retro-aldol reaction.
118:6078-6079.
1996
-
Azatides: Solution and liquid phase syntheses of a new peptidomimetic.
118:2539-2544.
1996
-
Catalytic antibodies with peptidyl-prolyl cis-trans isomerase activity.
118:5496-5497.
1996
-
Collagen-based structures containing the peptoid residue n-isobutylglycine (nleu) .6. Conformational analysis of gly-pro-nleu sequences by h-1 NMR, cd, and molecular modeling.
118:10725-10732.
1996
-
Collagen-like triple helices incorporating peptoid residues.
118:10928-10929.
1996
-
Copying nature's mechanism for the decarboxylation of β-keto acids into catalytic antibodies by reactive immunization.
118:11720-11724.
1996
-
Cyclic guanidino-sugars with low pKa as transition-state analog inhibitors of glycosidases: Neutral instead of charged species are the active forms.
118:4227-4234.
1996
-
DNA carbohydrate interactions. Specific binding of head-to-head and head-to-tail dimers of the calicheamicin oligosaccharide to duplex DNA.
118:2303-2304.
1996
-
Diffusion filters for separation of solvent-protein and protein-protein nuclear overhauser effects (hydra).
118:11629-11634.
1996
-
Distal pocket polarity in the unusual ligand binding site of soluble guanylate cyclase: implications for the control of .NO binding.
118:8769-8770.
1996
-
Enantioselective total synthesis of (+)-duocarmycin A, epi-(+)-duocarmycin a, and their unnatural enantiomers.
118:2301-2302.
1996
-
Energetics of a low barrier hydrogen bond in nonpolar solvents.
118:8575-8579.
1996
-
Enzymatic/chemical synthesis and biological evaluation of seven-membered iminocyclitols.
118:7647-7652.
1996
-
Generalized dipeptidomimetic template: solution phase parallel synthesis of combinatorial libraries.
118:2109-2110.
1996
-
Homocarbonates as substrates for the enantioselective enzymatic protection of amines.
118:712-713.
1996
-
Inhibition of oleamide hydrolase catalyzed hydrolysis of the endogenous sleep-inducing lipid cis-9-octadecenamide.
118:5938-5945.
1996
-
Mutagenesis study of active site residues in chorismate mutase from Bacillus subtilis.
118:1787-1788.
1996
-
Nature of the potential energy surfaces for the SN1 reaction: A picosecond kinetic study of homolysis and heterolysis for diphenylmethyl chlorides.
118:2992-2997.
1996
-
Novel solution phase strategy for the synthesis of chemical libraries containing small organic molecules.
118:2567-2573.
1996
-
Olefin metathesis in cyclic ether formation. Direct conversion of olefinic esters to cyclic enol ethers with tebbe-type reagents.
118:1565-1566.
1996
-
Porphyrin metalation catalyzed by a small RNA molecule.
118:7012-7013.
1996
-
Preparation of specifically deuterated RNA for NMR studies using a combination of chemical and enzymatic synthesis.
118:7929-7940.
1996
-
Probing protein/protein interactions with mass spectrometry and isotopic labeling: Analysis of the p21/cdk2 complex.
118:5320-5321.
1996
-
Rapid combinatorial synthesis of aminoglycoside antibiotic mimetics: Use of a polyethylene glycol-linked amine and a neamine-derived aldehyde in multiple component condensation as a strategy for the discovery of new inhibitors of the hiv rna rev responsive element.
118:10150-10155.
1996
-
Rational design and synthesis of a 1,1-linked disaccharide that is 5 times as active as sialyl lewis x in binding to e-selectin.
118:9265-9270.
1996
-
Self-assembling peptide nanotubes.
118:43-50.
1996
-
Site-specific protein modification using a ketone handle.
118:8150-8151.
1996
-
Solid-phase synthesis of 6-deoxyoligosaccharides.
118:9998-9999.
1996
-
Soluble polymer-bound ligand-accelerated catalysis: Asymmetric dihydroxylation.
118:7632-7633.
1996
-
Solution structure of the head-to-head dimer of calicheamicin oligosaccharide domain and d(cgtaggatatcctacg)(2).
118:8817-8824.
1996
-
Structure determination of an endogenous sleep-inducing lipid, cis-9-octadecenamide (oleamide): A synthetic approach to the chemical analysis of trace quantities of a natural product.
118:580-590.
1996
-
Studies on the synthesis of nargenicin A(1): highly stereoselective synthesis of the complete carbon framework via the transannular Diels-Alder reaction of an 18-membered macrolide.
118:7502-7512.
1996
-
Synergistic inhibition of human alpha-1,3-fucosyltransferase v.
118:7653-7662.
1996
-
Synthesis of sialyl Lewis X mimetics and related structures using the glycosyl phosphite methodology and evaluation of E-selectin inhibition.
118:6826-6840.
1996
-
Synthesis, X-ray structure, and properties of fluorocyclopropane analogs of the duocarmycins incorporating the 9,9-difluoro-1,2,9,9a-tetrahydrocyclopropa c benzo e indol-4-one (F2CBI) alkylation subunit.
118:8860-8870.
1996
-
Tetramethoxy calix[4]arenes revisited: conformational control through self-assembly.
118:10002-10003.
1996
-
The cua center of a soluble domain from thermus cytochrome ba(3). An NMR investigation of the paramagnetic protein.
118:11658-11659.
1996
-
Total synthesis of swinholide a.
118:3059-3060.
1996
-
Toward an understanding of the high enantioselectivity in the osmium-catalyzed asymmetric dihydroxylation .3. New insights into isomeric forms of the putative osmaoxetane intermediate.
118:35-42.
1996
-
Useful information from axial peak magnetization in projected NMR experiments.
118:8146-8147.
1996
-
3(10) helixes in peptides and proteins as studied by modified Zimm-Bragg theory.
117:10098-10103.
1995
-
Chemical ligation of cysteine-containing peptides: synthesis of a 22 kDa tethered dimer of HIV-1 protease.
117:1881-1887.
1995
-
Metal-catalyzed dehydropolymerization of secondary stannanes to high-molecular-weight polystannanes.
117:9931-9940.
1995
-
A remarkably stable transition-metal benzyne complex - synthesis and structure of cp(pme(3))(eta(2)-c6h4)ta(et(2)c(2)b(4)h(4))(1).
117:1163-1164.
1995
-
Acyl transfer versus catalysis with avidin.
117:8482-8483.
1995
-
An antibody-catalyzed nucleophilic-substitution reaction at a primary carbon that appears to proceed by an ionization mechanism.
117:2367-2368.
1995
-
An organometallic diradical cycloaromatization reaction.
117:8045-8046.
1995
-
Analysis of hydrogen bonding strengths in proteins using unnatural amino acids.
117:9361-9362.
1995
-
Anti-metallocene antibodies: A new approach to enantioselective catalysis of the Diels-Alder reaction.
117:7041-7047.
1995
-
Antibody catalysis of multistep reactions - an aldol addition followed by a disfavored elimination.
117:9383-9387.
1995
-
Base-analog-induced aminoacylation of an RNA helix by a tRNA synthetase.
117:7253-7254.
1995
-
Catalytic antibodies in organic-synthesis - asymmetric-synthesis of (-)-alpha-multistriatin.
117:3653-3654.
1995
-
Chemical synthesis and biological evaluation of c-2 taxoids.
117:2409-2420.
1995
-
Combined osmium rhenium approach to synthesis of naturally-occurring polyethers.
117:1447-1448.
1995
-
Control of self-assembly and reversible encapsulation of xenon in a self-assembling dimer by acid-base chemistry.
117:85-88.
1995
-
Convergent functional groups. 16. Hydrolysis of phosphate triesters by a novel cleft. Influence of binding on overall rate acceleration.
117:2210-2213.
1995
-
DNA alkylation properties of CC-1065 and duocarmycin analogs incorporating the 2,3,10,10a-tetrahydrocyclopropa d benzo f quinol-5-one alkylation subunit - identification of subtle structural features that contribute to the regioselectivity of the adenine N3 alkylation reaction.
117:11647-11655.
1995
-
Design and synthesis of sialyl-Lewis X mimetics.
117:5395-5396.
1995
-
Enzymatic-synthesis and regeneration of 3'-phosphoadenosine 5'-phosphosulfate (PAPS) for regioselective sulfation of oligosaccharides.
117:8031-8032.
1995
-
Enzymatic-synthesis of hyaluronic-acid with regeneration of sugar nucleotides.
117:5869-5870.
1995
-
Key synthetic analogs of bleomycin A(2) that directly address the effect and role of the disaccharide - demannosylbleomycin A(2) and alpha-D-mannopyranosyldeglycobleomycin A(2).
117:7344-7356.
1995
-
Ligand recognition by e-selectin - synthesis, inhibitory activity, and conformational-analysis of bivalent sialyl-lewis-x analogs.
117:66-79.
1995
-
Linear free-energy analysis of hydrogen-bonding in proteins.
117:1157-1158.
1995
-
Macrocyclic peptide inhibitors of serine proteases - convergent total synthesis of cyclotheonamide-a and cyclotheonamide-b via a late-stage primary amine intermediate - study of thrombin inhibition under diverse conditions.
117:1225-1239.
1995
-
Mechanism of lithium dialkylamide-mediated ketone and imine deprotonations - an mndo study of monomer and open dimer pathways.
117:2166-2178.
1995
-
Mechanistic studies of antibody-catalyzed pyrimidine dimer photocleavage.
117:5453-5461.
1995
-
N-desmethyl derivatives of deoxybouvardin and RA-VII: synthesis and evaluation.
117:7364-7378.
1995
-
Observation of a RuCl2((S)-((-))-tol-binap) (2).N(C2H5)(3)-catalyzed isomerization-hydrogenation network.
117:12647-12648.
1995
-
Oxepane synthesis along a disfavored pathway - the rerouting of a chemical-reaction using a catalytic antibody.
117:2659-2660.
1995
-
Peptidomimetic host that binds a peptide guest affording a beta-sheet structure that subsequently self-assembles. A simple receptor mimic.
117:1655-1656.
1995
-
Probing the structural determinants of a catalytic RNA with isomerase activity.
117:10145-10146.
1995
-
Recombinant 2-deoxyribose-5-phosphate aldolase in organic-synthesis - use of sequential 2-substrate and 3-substrate aldol reactions.
117:3333-3339.
1995
-
Remarkable ability of different antibody catalysts to control and diversify the product outcome of cationic cyclization reactions.
117:3308-3309.
1995
-
Second definitive test of proposed models for the origin of the CC-1065 and duocarmycin DNA alkylation selectivity.
117:1443-1444.
1995
-
Selectivity in the inhibition of HIV and FIV protease - inhibitory and mechanistic studies of pyrrolidine-containing alpha-keto amide and hydroxyethylamine core structures.
117:11867-11878.
1995
-
Sequential 3-substrate and 4-substrate aldol reactions catalyzed by aldolases.
117:7585-7591.
1995
-
Sequential one-pot aldol reactions catalyzed by 2-deoxyribose-5-phosphate aldolase and fructose-1,6-diphosphate aldolase.
117:2947-2948.
1995
-
Shape and stereoselective cyclopropanation of alkenes catalyzed by iron porphyrins.
117:9194-9199.
1995
-
Solution-phase conformational studies of the cyclic peptide RA-VII: lithium-chloride perturbation of the conformational equilibria.
117:7357-7363.
1995
-
Spectroscopic studies on the designed metal-binding sites of the 43c9 single-chain antibody.
117:5627-5634.
1995
-
Structure and dynamics of self-assembling peptide nanotubes and the channel-mediated water organization and self-diffusion - a molecular-dynamics study.
117:9151-9158.
1995
-
Studies on the mechanism of action of isoniazid and ethionamide in the chemotherapy of tuberculosis.
117:5009-5010.
1995
-
Studies on the synthesis of aureolic acid antibiotics: highly stereoselective synthesis of aryl 2-deoxy-beta-glycosides via the Mitsunobu reaction and synthesis of the olivomycin A-B disaccharide.
117:2236-2250.
1995
-
Supramolecular design by covalent capture - design of a peptide cylinder via hydrogen-bond-promoted intermolecular olefin metathesis.
117:12364-12365.
1995
-
Synthesis and efficacy of square planar copper complexes designed to nucleate beta-sheet structure.
117:2533-2546.
1995
-
Synthesis and evaluation of the fully functionalized bleomycin A(2) metal-binding domain-containing the 2-O-(3-O-carbamoyl-alpha-D-mannopyranosyl)-alpha-L-gulopyranosyl disaccharide.
117:7338-7343.
1995
-
Synthesis and self-assembly of pseudo-spherical homo- and heterodimeric capsules.
117:12733-12745.
1995
-
The potential application of catalytic antibodies to protecting group removal - catalytic antibodies with broad substrate tolerance.
117:2123-2127.
1995
-
The streptomyces-glaucescens tcmkl polyketide synthase and tcmn polyketide cyclase genes govern the size and shape of aromatic polyketides.
117:6811-6821.
1995
-
Total synthesis of brevetoxin-b .1. Cdefg framework.
117:1171-1172.
1995
-
Total synthesis of brevetoxin-b .1. First generation strategies and new approaches to oxepane systems.
117:10227-10238.
1995
-
Total synthesis of brevetoxin-b .2. 2nd generation strategies and construction of the dioxepane region defg.
117:10239-10251.
1995
-
Total synthesis of brevetoxin-b .2. Completion.
117:1173-1174.
1995
-
Total synthesis of brevetoxin-b .3. Final strategy and completion.
117:10252-10263.
1995
-
Total synthesis of granditropone, grandirubrine, imerubrine, and isoimerubrine.
117:12452-12459.
1995
-
Total synthesis of natural and ent-fredericamycin-a.
117:11839-11849.
1995
-
Total synthesis of taxol .1. Retrosynthesis, degradation, and reconstitution.
117:624-633.
1995
-
Total synthesis of taxol .2. Construction of a-ring and c-ring intermediates and initial attempts to construct the abc ring-system.
117:634-644.
1995
-
Total synthesis of taxol .3. Formation of taxols abc ring skeleton.
117:645-652.
1995
-
Total synthesis of taxol .4. The final stages and completion of the synthesis.
117:653-659.
1995
-
Investigation of medium effects in a family of decarboxylase antibodies.
116:7959-7963.
1994
-
Monitoring catalytic activity by immunoassay: implications for screening.
116:6101-6106.
1994
-
Total synthesis of crystalline (+/-)-fredericamycin A. Use of radical spirocyclization.
116:11275-11286.
1994
-
(+)- and ent-(-)-duocarmycin SA and (+)- and ent-(-)-N-BOC-DSA DNA alkylation properties - alkylation site models that accommodate the offset AT-rich adenine N3 alkylation selectivity of the enantiomeric agents.
116:1635-1656.
1994
-
A new route to deoxythiosugars based on aldolases.
116:6191-6194.
1994
-
A novel and efficient synthesis of neolacto series gangliosides 3'-nlm(1) and 6'nlm(1).
116:1149-1150.
1994
-
An antibody-catalyzed oxy-Cope rearrangement.
116:2211-2212.
1994
-
An efficient antibody-catalyzed oxygenation reaction.
116:2167-2168.
1994
-
Antibody-catalyzed activation of unfunctionalized olefins for highly enantioselective asymmetric epoxidation.
116:803-804.
1994
-
Antibody-catalyzed prodrug activation.
116:2165-2166.
1994
-
Application of eta4-diene iron tricarbonyl complexes in acyclic stereocontrol: asymmetric synthesis of the as-indacene unit of ikarugamycin (a formal total synthesis).
116:2151-2152.
1994
-
Binding of hapten to a single chain catalytic antibody demonstrated by electrospray mass spectrometry.
116:7937-7938.
1994
-
CBI-TMI - synthesis and evaluation of a key analog of the duocarmycins - validation of a direct relationship between chemical solvolytic stability and cytotoxic potency and confirmation of the structural features responsible for the distinguishing behavior of enantiomeric pairs of agents.
116:7996-8006.
1994
-
Carbohydrate minor-groove interactions in the binding of calicheamicin gamma-1(i) to duplex DNA.
116:3709-3715.
1994
-
Channel-mediated transport of glucose across lipid bilayers.
116:10785-10786.
1994
-
Chemical and structural comparison of N-BOC-CBQ and N-BOC-CBI - identification and structural origin of an unappreciated but productive stability of the CC-1065 and duocarmycin SA alkylation subunits.
116:6461-6462.
1994
-
Chemical probe for glycosidic conformation in telomeric DNAs.
116:4479-4480.
1994
-
Convergent functional groups. 15. Studies of large and rigid molecular clefts.
116:5145-5149.
1994
-
Creation of a novel biosensor for zinc(II).
116:415-416.
1994
-
Crossing extreme mechanistic barriers by antibody catalysis: Syn elimination to a cis olefin.
116:6013-6014.
1994
-
Density-functional Poisson-Boltzmann calculations of redox potentials for iron-sulfur clusters.
116:11898-11914.
1994
-
Design, synthesis, and evaluation of CC-1065 and duocarmycin analogs incorporating the 2,3,10,10a-tetrahydro-1H-cyclopropa d benzo f quinol-5-one (CBQ) alkylation subunit - identification and structural origin of subtle stereoelectronic features that govern reactivity and regioselectivity.
116:11335-11348.
1994
-
Differential side chain hydration in a linear peptide containing a type VI turn.
116:12051-12052.
1994
-
Enantioselective total synthesis of (-)-chlorothricolide.
116:6457-6458.
1994
-
Engineering subtilisin for peptide coupling - studies on the effects of counterions and site-specific modifications on the stability and specificity of the enzyme.
116:6521-6530.
1994
-
Evidence for a cyclic mechanism in (eta(3)-allyl)palladium chemistry - promotion of beta-hydride elimination by unsaturated organometallics.
116:11151-11152.
1994
-
Hydrophobic cluster formation is necessary for dibenzofuran-based amino acids to function as beta-sheet nucleators.
116:3988-4005.
1994
-
Interaction of calicheamicin with duplex DNA - role of the oligosaccharide domain and identification of multiple binding modes.
116:3697-3708.
1994
-
Intracomplex catalysis of acylation reactions.
116:11592-11593.
1994
-
Intramolecular benzannulation reactions of chromium siloxycarbene complexes - regiochemical control and the xenochemical effect of alkyne additives.
116:10921-10933.
1994
-
Lithium dialkylamide mixed aggregation - an NMR spectroscopic study of the influence of hexamethylphosphoramide (hmpa).
116:9198-9202.
1994
-
Lithium dialkylamide mixed aggregation - mndo computational study of salt and solvent dependencies.
116:9187-9197.
1994
-
Mechanistic studies of an antibody-catalyzed elimination reaction.
116:2261-2270.
1994
-
Mechanistic studies of the oxidation of isoniazid by the catalase peroxidase from Mycobacterium tuberculosis.
116:7425-7426.
1994
-
Nanoscale tubular ensembles with specified internal diameters - design of a self-assembled nanotube with a 13 Å pore.
116:6011-6012.
1994
-
New evidence for template effects in a self-replicating system.
116:8823-8824.
1994
-
Nmr order parameters of biomolecules - a new analytical representation and application to the gaussian axial fluctuation model.
116:8426-8427.
1994
-
Recognition of DNA by synthetic antibodies.
116:2161-2162.
1994
-
Role of geometrical factors in template effects.
116:10296-10297.
1994
-
Role of the CC-1065 and duocarmycin N-2 substituent - validation of a direct relationship between solvolysis chemical-stability and in-vitro biological potency.
116:5523-5524.
1994
-
Self-replicating molecules: a second generation.
116:8877-8884.
1994
-
Sequence-corrected n-15 random coil chemical-shifts.
116:8466-8469.
1994
-
Solid-phase chemical-enzymatic synthesis of glycopeptides and oligosaccharides.
116:1135-1136.
1994
-
Solution-phase and solid-phase synthesis of inhibitors of helicobacter-pylori attachment and e-selectin-mediated leukocyte adhesion.
116:11315-11322.
1994
-
Stereoselective antibody-catalyzed oxime formation.
116:1145-1146.
1994
-
Synthesis of carbohydrates via tandem use of the osmium-catalyzed asymmetric dihydroxylation and enzyme-catalyzed aldol addition-reactions.
116:558-561.
1994
-
Synthesis of novel taxoids.
116:1591-1592.
1994
-
Synthesis, structure, and reactivity of (mu-oxo)bis(mu-carboxylato)diiron(III) complexes of a dinucleating dicarboxylate ligand, stable models for non-heme diiron protein cores.
116:5196-5205.
1994
-
Total syntheses of (+)-p-3a, epi-(-)-p-3a, and (-)-desacetamido p-3a.
116:82-92.
1994
-
Total synthesis of balanol.
116:8402-8403.
1994
-
Total synthesis of bleomycin A(2) and related agents .4. Synthesis of the disaccharide subunit - 2-O-(3-O-carbamoyl-alpha-D-mannopyranosyl)-L-gulopyranose and completion of the total synthesis of bleomycin a(2).
116:5647-5656.
1994
-
Total synthesis of bleomycin-A(2) and related agents .1. Synthesis and DNA-binding properties of the extended C-terminus - tripeptide-S, tetrapeptide-S, pentapeptide-S, and related agents.
116:5607-5618.
1994
-
Total synthesis of bleomycin-A(2) and related agents .2. Synthesis of (-)-pyrimidoblamic acid, epi-(+)-pyrimidoblamic acid, (+)-desacetamidopyrimidoblamic acid, and (-)-descarboxamidopyrimidoblamic acid.
116:5619-5630.
1994
-
Total synthesis of bleomycin-A(2) and related agents .3. Synthesis and comparative-evaluation of deglycobleomycin-A(2), epideglycobleomycin-A(2), deglycobleomycin-A(1), and desacetamidodeglycobleomycin, descarboxamidodeglycobleomycin, desmethyldeglycobleomycin, and desimidazolyldeglycobleomycin-A(2).
116:5631-5646.
1994
-
Total synthesis of bouvardin, O-methylbouvardin, and O-methyl-N-9-desmethylbouvardin.
116:8544-8556.
1994
-
Total synthesis of truncated brevetoxin-b afghijk.
116:9371-9372.
1994
-
Toward an understanding of the high enantioselectivity in the osmium-catalyzed asymmetric dihydroxylation (ad) .1. Kinetics.
116:1278-1291.
1994
-
Toward an understanding of the high enantioselectivity in the osmium-catalyzed asymmetric dihydroxylation .2. A qualitative molecular mechanics approach.
116:8470-8478.
1994
-
Transport of adenine mononucleoside and dinucleoside monophosphates across liquid membranes and extraction of oligonucleotides with synthetic carriers.
116:5501-5502.
1994
-
Unprecedented asymmetric aldol reactions with 3 aldehyde substrates catalyzed by 2-deoxyribose-5-phosphate aldolase.
116:8422-8423.
1994
-
Water-soluble receptors for cyclic-AMP and their use for evaluating phosphate-guanidinium interactions.
116:3279-3284.
1994
-
[(Z)-gamma-[(Diisopropylidene-alpha-D-mannopyranosyl)oxy]allyl]tributylstannane: a new chiral reagent for the asymmetric alpha-hydroxyallylation of aldehydes.
116:8536-8543.
1994
-
Correlating hydration shell structure with amino acid hydrophobicity.
115:3336-3337.
1993
-
(-)-sandramycin - total synthesis and preliminary DNA-binding properties.
115:11624-11625.
1993
-
A catalytic antibody model for plp-dependent decarboxylases.
115:2515-2516.
1993
-
A dramatic ligand effect on the relative reactivities of substituted alkenes with osmium-tetroxide.
115:7047-7048.
1993
-
A highly specific metal-activated catalytic antibody.
115:4906-4907.
1993
-
A novel strategy for synthesis of ganglioside-gm3 using an enzymatically produced sialoside glycosyl donor.
115:1603-1605.
1993
-
Antibody-catalyzed enantioselective epoxide hydrolysis.
115:4893-4894.
1993
-
Antibody-catalyzed hydrolysis of enol ethers.
115:3909-3917.
1993
-
Application of the steric directing group strategy to the stereoselective synthesis of the octahydronaphthalene substructure of kijanolide and tetronolide.
115:2268-2278.
1993
-
Catalytic antibodies from combinatorial libraries.
115:357-358.
1993
-
Catalytic asymmetric dihydroxylation of tetrasubstituted olefins.
115:8463-8464.
1993
-
Characterization of amino-acid side-chain dynamics in a zinc-finger peptide using c-13 NMR-spectroscopy and time-resolved fluorescence spectroscopy.
115:6333-6345.
1993
-
Combined use of trans-sialidase and sialyltransferase for enzymatic-synthesis of alpha-neuac2-- 3-beta-gal-or.
115:7862-7863.
1993
-
Convenient total synthesis of a 4-helix TASP molecule by chemoselective ligation.
115:7263-7266.
1993
-
Convergent functional groups. 13. High-affinity complexation of adenosine derivatives within induced binding pockets.
115:3548-3557.
1993
-
D, l- and meso-isochrysohermidin - total synthesis and interstrand DNA cross-linking.
115:11418-11425.
1993
-
De-novo design and synthesis of somatostatin nonpeptide peptidomimetics utilizing beta-d-glucose as a novel scaffolding.
115:12550-12568.
1993
-
Design, synthesis, and partial characterization of water-soluble beta-sheets stabilized by a dibenzofuran-based amino acid.
115:3790-3791.
1993
-
Detection of 2 histidyl ligands to cu-a of cytochrome-oxidase by 35-ghz endor - n-14,15 and cu-63,65 endor studies of the cu-a site in bovine heart cytochrome-aa(3) and cytochrome-caa(3) and cytochrome-ba(3) from thermus-thermophilus.
115:10888-10894.
1993
-
Determination of local ligand conformations in slowly tumbling proteins by homonuclear 2d and 3d NMR - application to heme propionates in leghemoglobin.
115:6238-6246.
1993
-
Engineering metal coordination sites into the antibody light-chain.
115:4449-4456.
1993
-
Enzymatic-synthesis of N-linked and O-linked glycopeptides.
115:5893-5901.
1993
-
Evidence of ca2+-dependent carbohydrate association through ion spray mass-spectrometry.
115:2877-2881.
1993
-
Identification of the active catalyst in the rhodium porphyrin-mediated cyclopropanation of alkenes.
115:1656-1660.
1993
-
Isolation and structure determination of 2-amino-2-deoxyisochorismate - an intermediate in the biosynthesis of anthranilate.
115:816-817.
1993
-
Kinetic resolution of racemic olefins via asymmetric dihydroxylation.
115:7864-7865.
1993
-
Ligand recognition by e-selectin - analysis of conformation and activity of synthetic monomeric and bivalent sialyl lewis-x analogs.
115:7549-7550.
1993
-
Molecular design, chemical synthesis, kinetic-studies, calculations, and biological studies of novel enediynes equipped with triggering, detection, and deactivating devices - model dynemicin-a epoxide and cis-diol systems.
115:7944-7953.
1993
-
Molecular recognition in water: new receptors for adenine derivatives.
115:797-798.
1993
-
Nmr1 detection of hydration water in the intermolecular interface of a protein-DNA complex.
115:1189-1190.
1993
-
Probing the role of lysine 16 in Ras p(21) protein with unnatural amino acids.
115:6414-6415.
1993
-
Protein biosynthesis with conformationally restricted amino acids.
115:4359-4360.
1993
-
Reduced dimensionality in triple-resonance NMR experiments.
115:9307-9308.
1993
-
Reversibility of the duocarmycin-A and SA DNA alkylation reaction.
115:9872-9873.
1993
-
Singlet oxygen oxidation of bipyrroles - total synthesis of d,l-isochrysohermidin and meso-isochrysohermidin.
115:8457-8458.
1993
-
Structure of lithium hexamethyldisilazide (lihmds) in the presence of hexamethylphosphoramide (hmpa) - spectroscopic and computational studies of monomers, dimers, and triple ions.
115:3475-3483.
1993
-
Synthesis and use of glycosyl phosphites - an effective route to glycosyl phosphates, sugar nucleotides, and glycosides.
115:2260-2267.
1993
-
Synthesis of 3-deoxy-d-manno-2-octulosonic acid (kdo) and its analogs based on kdo aldolase-catalyzed reactions.
115:413-421.
1993
-
Synthesis of phospholipid inhibitor conjugates by enzymatic transphosphatidylation with phospholipase-d.
115:10487-10491.
1993
-
Synthetic methods for the implementation of encoded combinatorial chemistry.
115:9812-9813.
1993
-
The energetic advantage of 5-exo versus 6-endo epoxide openings - a preference overwhelmed by antibody catalysis.
115:8453-8454.
1993
-
The origin of high enantioselectivity in the dihydroxylation of olefins using osmium tetraoxide and cinchona alkaloid catalysts.
115:12226-12227.
1993
-
Total synthesis and preliminary evaluation of (+)-duocarmycin and ent-(-)-duocarmycin SA.
115:9025-9036.
1993
-
Total synthesis of (+)-piperazinomycin.
115:11426-11433.
1993
-
Total synthesis of calicheamicin-gamma-1(i) .1. Synthesis of the oligosaccharide fragment.
115:7593-7611.
1993
-
Total synthesis of calicheamicin-gamma-1(i) .2. Development of an enantioselective route to (-)-calicheamicinone.
115:7612-7624.
1993
-
Total synthesis of calicheamicin-gamma-1(i) .3. The final stages.
115:7625-7635.
1993
-
Total synthesis of cycloisodityrosine, RA-VII, deoxybouvardin, and N29-desmethyl-RA-VII - identification of the pharmacophore and reversal of the subunit functional roles.
115:3420-3430.
1993
-
Total synthesis of hemibrevetoxin-b and (7a-alpha)-epi-hemibrevetoxin-b.
115:3558-3575.
1993
-
Total synthesis of naturally-occurring acetogenins - solamin and reticulatacin.
115:4891-4892.
1993
-
Total synthesis of rapamycin.
115:4419-4420.
1993
-
Total synthesis of streptonigrone.
115:10733-10741.
1993
-
Total synthesis of sulfated le(x) and le(a)-type oligosaccharide selectin ligands.
115:8843-8844.
1993
-
Defining hydrophobicity: probing the structure of solute-induced hydration shells by Fourier transform infrared spectroscopy.
114:4336-4339.
1992
-
Direct observation of a ternary complex between the dimeric enzyme HIV-1 protease and a substrate-based inhibitor.
114:3992-3993.
1992
-
A chromogenic assay for screening large antibody libraries.
114:1486-1487.
1992
-
A convergent approach to protein design - metal ion-assisted spontaneous self-assembly of a polypeptide into a triple-helix bundle protein.
114:825-831.
1992
-
A dibenzofuran-based amino acid designed to nucleate antiparallel beta-sheet structure: evidence for intramolecular hydrogen-bond formation.
114:8316-8318.
1992
-
A new approach toward the inhibition of ribonucleases - a water-stable ribonucleoside technetium chelate.
114:1488-1489.
1992
-
A new chiral auxiliary for asymmetric thermal reactions: high stereocontrol in radical addition, allylation, and annulation reactions.
114:7007-7018.
1992
-
A transition-state model for the rhodium porphyrin-catalyzed cyclopropanation of alkenes by diazo esters.
114:8336-8338.
1992
-
An antibody-catalyzed dehydration reaction.
114:6573-6574.
1992
-
Beta-sialyl phosphite and phosphoramidite - synthesis and application to the chemoenzymatic synthesis of cmp-sialic acid and sialyl oligosaccharides.
114:8748-8750.
1992
-
Catalytic asymmetric dihydroxylation of cis-disubstituted olefins.
114:7568-7570.
1992
-
Chemical-enzymatic synthesis and conformational-analysis of sialyl lewis-x and derivatives.
114:9283-9298.
1992
-
Cluster sialoside inhibitors for influenza-virus - synthesis, NMR, and biological studies.
114:8363-8375.
1992
-
Conformational studies of sialyl lewis-x in aqueous-solution.
114:5452-5454.
1992
-
DNA alkylation properties of enhanced functional analogs of cc-1065 incorporating the 1,2,9,9a-tetrahydrocyclopropa 1,2-c benz 1,2-e indol-4-one (cbi) alkylation subunit.
114:5487-5496.
1992
-
DNA carbohydrate interactions - specific binding of the calicheamicin-gamma-1i oligosaccharide with duplex DNA.
114:7555-7557.
1992
-
Deoxyribose-5-phosphate aldolase as a catalyst in asymmetric aldol condensation.
114:741-748.
1992
-
Design of an artificial 4-helix bundle metalloprotein via a novel ruthenium(ii)-assisted self-assembly process.
114:4000-4002.
1992
-
Design, synthesis, and study of simple monocyclic conjugated enediynes - the 10-membered ring enediyne moiety of the enediyne anticancer antibiotics.
114:7360-7371.
1992
-
Determination of structures of solvated lithium dialkylamides by semiempirical (mndo) methods - comparison of theory and experiment.
114:2112-2121.
1992
-
Enantioselective total synthesis of (-)-calicheamicinone.
114:3134-3136.
1992
-
Functional analogs of CC-1065 and the duocarmycins incorporating the 9A-(chloromethyl)-1,2,9,9a-tetrahydrocyclopropa c benz e indol-4-one (C2BI) alkylation subunit - synthesis and preliminary DNA alkylation studies.
114:9318-9327.
1992
-
Highly enantioselective protonation catalyzed by an antibody.
114:2257-2258.
1992
-
Intramolecular benzannulation reactions of manganese carbene complexes.
114:8735-8736.
1992
-
LCAO X alpha calculation of the magnetic exchange interactions in a Mn(IV)Mn(III)3 cubane complex: relevance to the water oxidation center of photosystem II.
114:6109-6119.
1992
-
Molecular design and chemical synthesis of potent enediynes .1. Dynemicin model systems equipped with n-tethered triggering devices.
114:8890-8907.
1992
-
Molecular design and chemical synthesis of potent enediynes .2. Dynemicin model systems equipped with c-3 triggering devices and evidence for quinone methide formation in the mechanism of action of dynemicin-a.
114:8908-8921.
1992
-
Nonpeptidal peptidomimetics with a beta-d-glucose scaffolding - a partial somatostatin agonist bearing a close structural relationship to a potent, selective substance-p antagonist.
114:9217-9218.
1992
-
Novel tight-binding inhibitors of leukotriene-a(4) hydrolase.
114:6552-6553.
1992
-
Organotransition-metal metallacarboranes .26. Carborane ligands in organometallic chemistry - a new class of fischer carbene complexes.
114:8733-8735.
1992
-
Overproduction of cmp-sialic acid synthetase for organic-synthesis.
114:3901-3910.
1992
-
Polypeptide hydration in mixed-solvents at low-temperatures.
114:7093-7095.
1992
-
Psi PO2-CH2N+ , a new amide bond replacement - potent, slow-binding inhibition of the HIV protease.
114:7604-7606.
1992
-
Redox-controlled bergman cycloaromatizations - designed enediynes with DNA-cleaving properties and antitumor-activity.
114:9279-9282.
1992
-
Remarkable regioselectivity in the chemical glycosylation of glycal acceptors - a concise solution to the synthesis of sialyl-lewis-x glycal.
114:8329-8331.
1992
-
Selective asymmetric dihydroxylation of dienes.
114:7570-7571.
1992
-
Site-specific isotopic labeling of proteins for NMR studies.
114:7959-7961.
1992
-
Specificity, inhibition, and synthetic utility of a recombinant human alpha-1,3-fucosyl-transferase.
114:7321-7322.
1992
-
Spectroscopic studies of a transcriptional activation peptide.
114:362-363.
1992
-
Stereospecific antibody-catalyzed reduction of an alpha-keto amide.
114:780-781.
1992
-
Structure and reactivity of lithium diisopropylamide in the presence of n,n,n',n'-tetramethylethylenediamine.
114:5100-5110.
1992
-
Substituent effects on an antibody-catalyzed hydrolysis of phenyl-esters - further evidence for an acyl-antibody intermediate.
114:3528-3534.
1992
-
Synthetic replicators and extrabiotic chemistry.
114:4529-4532.
1992
-
Total synthesis of (+)-duocarmycin SA.
114:10056-10058.
1992
-
Total synthesis of hemibrevetoxin-b.
114:7935-7936.
1992
-
Total synthesis of sialyl dimeric lex.
114:3126-3128.
1992
-
Total synthesis of the nodrm-iv factors, the rhizobium nodulation signals.
114:8701-8702.
1992
-
Unusual stereoselectivity in sialic-acid aldolase-catalyzed aldol condensations - synthesis of both enantiomers of high-carbon monosaccharides.
114:10138-10145.
1992
-
(+)-CC-1065 DNA alkylation - key studies demonstrating a noncovalent binding selectivity contribution to the alkylation selectivity.
113:3980-3983.
1991
-
(+)-CC-1065 DNA alkylation - observation of an unexpected relationship between cyclopropane electrophile reactivity and the intensity of DNA alkylation.
113:2779-2780.
1991
-
A complete change of stereoselectivity in sialic-acid aldolase reactions - a novel synthetic route to the kdo type of 9-carbon-l sugars.
113:7816-7818.
1991
-
A general and efficient route for chemical aminoacylation of transfer RNAs.
113:2722-2729.
1991
-
A highly efficient multienzyme system for the one-step synthesis of a sialyl trisaccharide - insitu generation of sialic-acid and n-acetyllactosamine coupled with regeneration of udp-glucose, udp-galactose, and cmp-sialic acid.
113:6300-6302.
1991
-
A synthetic receptor for dinucleotides.
113:9424-9425.
1991
-
Active-site-directed modification of subtilisin.
113:2259-2263.
1991
-
An antibody-catalyzed cis trans isomerization reaction.
113:2319-2321.
1991
-
Antibody bait and switch catalysis - a survey of antigens capable of inducing abzymes with acyl-transfer properties.
113:5427-5434.
1991
-
Antibody-catalyzed bimolecular imine formation.
113:6670-6672.
1991
-
Antibody-catalyzed hydrolysis of phosphate monoesters.
113:9397-9398.
1991
-
Asymmetric induction via a catalytic antibody.
113:7763-7764.
1991
-
Catalytic antibodies with acyl-transfer capabilities - mechanistic and kinetic investigations.
113:291-297.
1991
-
Construction of a light-activated protein by unnatural amino acid mutagenesis.
113:2758-2760.
1991
-
Convergent functional groups create a microenvironment for enolization catalysis.
113:1453-1454.
1991
-
Convergent functional groups. 10. Molecular recognition of neutral substrates.
113:201-209.
1991
-
Enantiofacial protonation by catalytic antibodies.
113:8528-8529.
1991
-
Engineering protein specificity: gene manipulation with semisynthetic nucleases.
113:9398-9400.
1991
-
Engineering subtilisin for reaction in dimethylformamide.
113:683-684.
1991
-
Enzyme-catalyzed aldol condensation for asymmetric-synthesis of azasugars - synthesis, evaluation, and modeling of glycosidase inhibitors.
113:6187-6196.
1991
-
Enzyme-catalyzed synthesis of sialyl oligosaccharide with insitu regeneration of cmp-sialic acid.
113:4698-4700.
1991
-
Epoxyquinones from 2,5-dihydroxyacetanilide - opposite facial specificity in the epoxidation by enzymes from streptomyces ll-c10037 and streptomyces mpp 3051.
113:684-686.
1991
-
General-approach to the synthesis of short alpha-helical peptides.
113:9391-9392.
1991
-
Intramolecular motions of a zinc finger DNA-binding domain from xfin characterized by proton-detected natural abundance c-12 heteronuclear NMR-spectroscopy.
113:4371-4380.
1991
-
Inverse electron demand Diels-Alder reactions of N-sulfonyl alpha,beta-unsaturated imines - a general-approach to implementation of the 4-pi participation of 1-aza-1,3-butadienes in Diels-Alder reactions.
113:1713-1729.
1991
-
Isolation and characterization of the duocarmycin adenine DNA adduct.
113:6645-6649.
1991
-
Kinetic studies and modeling of a self-replicating system.
113:8831-8839.
1991
-
Kinetic-studies of superoxide dismutases - properties of the manganese-containing protein from thermus-thermophilus.
113:4069-4076.
1991
-
Mechanism of asymmetric epoxidation .1. Kinetics.
113:106-113.
1991
-
Mechanism of asymmetric epoxidation .2. Catalyst structure.
113:113-126.
1991
-
New chiral auxiliary for asymmetric thermal reactions: high regio- and beta-stereoselectivity in asymmetric radical addition reactions to mixed fumarimides.
113:5918-5920.
1991
-
New molecular complements to imides. Complexation of thymine derivatives.
113:5125-5127.
1991
-
Novel enediynes equipped with triggering and detection devices - isolation of cis-diol models of the dynemicin-a cascade.
113:9878-9880.
1991
-
On the structure of lithium 2,2,6,6-tetramethylpiperidide (litmp) and lithium diisopropylamide (lda) in the presence of hexamethylphosphoramide (hmpa) - structure-dependent distribution of cyclic and open dimers, ion triplets, and monomers.
113:5751-5757.
1991
-
Palladium-mediated stereocontrolled reductive amination of azido sugars prepared from enzymatic aldol condensation - a general-approach to the synthesis of deoxy aza sugars.
113:6678-6680.
1991
-
Probing the acceptor specificity of beta-1,4-galactosyltransferase for the development of enzymatic-synthesis of novel oligosaccharides.
113:8137-8145.
1991
-
Proton proton overhauser effects of receptor-bound cyclosporine-a observed with the use of a heteronuclear-resolved half-filter experiment.
113:4676-4678.
1991
-
Proton-exchange with internal water-molecules in the protein bpti in aqueous-solution.
113:4363-4364.
1991
-
Pseudomonas-oleovorans monooxygenase catalyzed asymmetric epoxidation of allyl alcohol derivatives and hydroxylation of a hypersensitive radical probe with the radical ring-opening rate exceeding the oxygen rebound rate.
113:5878-5880.
1991
-
Redirecting the immune response: ligand-mediated immunogenicity.
113:1861-1862.
1991
-
Sigmoidal growth in a self-replicating system.
113:9422-9423.
1991
-
Soft stereoelectronic effects at carboxyl oxygen.
113:2247-2253.
1991
-
Synthesis and chemistry of dynemicin-a models.
113:3106-3114.
1991
-
Synthesis of cluster sialoside inhibitors for influenza-virus.
113:5865-5866.
1991
-
Total synthesis of (+/-)-cis-trikentrin-A and (+/-)-trans-trikentrin-A - Diels-Alder reactions of heteroaromatic azadienes.
113:4230-4234.
1991
-
Total synthesis of deoxybouvardin and RA-VII - macrocyclization via an intramolecular Ullmann reaction.
113:1427-1429.
1991
-
A new strategy for selective protein cleavage.
112:3249-3250.
1990
-
A self-replicating system.
112:1249-1250.
1990
-
Acyclic diastereoselective synthesis using tartrate ester modified crotylboronates: double asymmetric reactions with alpha-methyl chiral aldehydes and synthesis of the C19-C29 segment of rifamycin S.
112:6348-6359.
1990
-
An antibody-catalyzed bimolecular Diels-Alder reaction.
112:7430-7431.
1990
-
Asymmetric-synthesis using diisopropyl tartrate modified (E)-crotylboronates and (Z)-crotylboronates: preparation of the chiral crotylboronates and reactions with achiral aldehydes.
112:6339-6348.
1990
-
Bait and switch strategy for obtaining catalytic antibodies with acyl-transfer capabilities.
112:1274-1275.
1990
-
Bridging of macrodithionolactones to bicyclic systems - synthesis and modeling of oxapolycyclic frameworks.
112:3040-3054.
1990
-
Convergent functional groups. 8. Flexible model receptors for adenine derivatives.
112:8408-8414.
1990
-
Convergent functional groups. 9. Complexation in new molecular clefts.
112:8902-8906.
1990
-
DNA cleavage and antitumor-activity of designed molecules with conjugated phosphine oxide-allene-ene-yne functionalities.
112:7825-7826.
1990
-
Deoxyribose-5-phosphate aldolase as a synthetic catalyst.
112:2013-2014.
1990
-
Dithiatopazine and related systems - synthesis, chemistry, x-ray crystallographic analysis and calculations.
112:3029-3039.
1990
-
Duocarmycin pyrindamycin DNA alkylation properties and identification, synthesis, and evaluation of agents incorporating the pharmacophore of the duocarmycin pyrindamycin alkylation subunit - identification of the CC-1065-duocarmycin common pharmacophore.
112:8961-8971.
1990
-
Enzymes as synthetic catalysts - mechanistic and active-site considerations of natural and modified chymotrypsin.
112:5313-5320.
1990
-
Enzymes in organic synthesis: use of subtilisin and a highly stable mutant derived from multiple site-specific mutations.
112:945-953.
1990
-
Exchange of amide protons. Effect of intramolecular hydrogen bonding.
112:3122-3125.
1990
-
High-efficiency synthesis of sialyloligosaccharides and sialoglycopeptides.
112:9308-9309.
1990
-
Immobilized catalytic antibodies in aqueous and organic-solvents.
112:8886-8888.
1990
-
Intramolecular acyl radical alkene addition-reactions - macrocyclization reactions.
112:4008-4011.
1990
-
Molecular recognition. Asymmetric complexation of diketopiperazines.
112:6144-6145.
1990
-
New nuclear-magnetic-resonance experiment for measurements of the vicinal coupling-constants 3jhn-alpha in proteins.
112:3663-3665.
1990
-
New synthetic strategies for the construction of medium-size cyclic ethers - stereocontrolled synthesis of the bcd ring framework of brevetoxin-a.
112:3696-3697.
1990
-
Novel stereocontrolled synthesis of the nonacene ring-system of brevetoxin-a - conformational reactivity effects in 9-membered rings.
112:4988-4989.
1990
-
Novel strategy for the construction of the oligosaccharide fragment of calicheamicin-gamma-1-alpha-i - synthesis of the abc skeleton.
112:4085-4086.
1990
-
Peptide architecture - design of stable alpha-helical metallopeptides via a novel exchange-inert ruiii complex.
112:9633-9635.
1990
-
Peroxidase activity of an antibody heme complex.
112:9414-9415.
1990
-
Relative hydrogen-bonding affinities of imides and lactams.
112:3215-3217.
1990
-
Secondary structure nucleation in peptides - transition-metal ion stabilized alpha-helices.
112:1630-1632.
1990
-
Site-specific cleavage of duplex DNA with a lambda-repressor Staphylococcal nuclease hybrid.
112:4579-4580.
1990
-
Specific deuteration strategy for enhancing direct nuclear overhauser effects in high-molecular-weight complexes.
112:8183-8185.
1990
-
Stereoelectronic effects in cyclization reactions.
112:3685-3686.
1990
-
Synthesis and evaluation of aborted and extended CC-1065 functional analogs - (+)-CPI-PDE-1, and (-)-CPI-PDE-1, (+)-CPI-PDE-1, and (-)-CPI-CDPI1, and (+/-)-CPI-PDE-i1, (+)-CPI-PDE-i1, and (-)-CPI-CDPI3 - preparation of key partial structures and definition of an additional functional-role of the CC-1065 central and right-hand subunits.
112:4623-4632.
1990
-
Synthesis of dynemicin-a models.
112:7416-7418.
1990
-
Synthesis of medium-sized ring ethers from thionolactones - applications to polyether synthesis.
112:6263-6276.
1990
-
Synthesis of n-(phenylsulfonyl)-CI, N-((tert-butyloxy)carbonyl)-CI, CI-CDPI1, and CI-CDPI2 - CC-1065 functional analogs incorporating the parent 1,2,7,7a-tetrahydrocycloprop 1,2-c indol-4-one (CI) left-hand subunit.
112:5230-5240.
1990
-
Tandem free-radical alkene addition-reactions of acyl radicals.
112:4003-4008.
1990
-
Total synthesis of the oligosaccharide fragment of calicheamicin gamma-1i.
112:8193-8195.
1990
-
Total synthesis of the tumor-associated le(x) family of glycosphingolipids.
112:3693-3695.
1990
-
Use of a double-half-filter in 2-dimensional 1h nuclear-magnetic-resonance studies of receptor-bound cyclosporine.
112:9015-9016.
1990
-
1,1'-carbonylbis(3-methylimidazolium) triflate: an efficient reagent for aminoacylations.
111:4856-4859.
1989
-
A general-solution to implementing the 4-p participation of 1-aza-1,3-butadienes in Diels-Alder reactions - inverse electron demand Diels-Alder reactions of alpha,beta-unsaturated n-benzenesulfonyl imines.
111:1517-1519.
1989
-
A highly stereoselective synthesis of (+)-olivin, the aglycon of olivomycin A.
111:2984-2995.
1989
-
A mechanistic insight leads to a greatly improved osmium-catalyzed asymmetric dihydroxylation process.
111:1123-1125.
1989
-
A semisynthetic catalytic antibody.
111:1929-1931.
1989
-
Activation of 6-endo over 5-exo hydroxy epoxide openings - stereoselective and ring selective synthesis of tetrahydrofuran and tetrahydropyran systems.
111:5330-5334.
1989
-
Activation of 7-endo over 6-exo epoxide openings - synthesis of oxepane and tetrahydropyran systems.
111:5335-5340.
1989
-
Aminolysis of benzoyl fluorides in water.
111:8479-8484.
1989
-
Automated stereospecific h-1-NMR assignments and their impact on the precision of protein-structure determinations in solution.
111:3997-4004.
1989
-
Biosynthesis of antibiotic ll-c10037-alpha - the steps beyond 3-hydroxyanthranilic acid.
111:7932-7938.
1989
-
Conformational study of cinchona alkaloids - a combined NMR, molecular mechanics, and x-ray approach.
111:8069-8076.
1989
-
Cyclizations of hydroxy dithioketals - new synthetic technology for the construction of oxocenes and related medium-ring systems.
111:5321-5330.
1989
-
Experimental-observation of orientational dispersion in the peptide backbone of the gramicidin cation channel.
111:400-401.
1989
-
Free-radical cyclizations - application to the total synthesis of dl-pleurotin and dl-dihydropleurotin acid.
111:7507-7519.
1989
-
Intramolecular catalysis of enolization: a probe for stereoelectronic effects at carboxyl oxygen.
111:4503-4505.
1989
-
Kinetic role of the alkaloid ligands in asymmetric catalytic dihydroxylation.
111:737-739.
1989
-
Mechanism of solvolysis of substituted benzoyl halides.
111:8470-8479.
1989
-
Metalloselective anti-porphyrin monoclonal-antibodies.
111:2344-2346.
1989
-
Molecular recognition with convergent functional groups. 6. Synthetic and structural studies with a model receptor for nucleic acid components.
111:1082-1090.
1989
-
Molecular recognition with convergent functional groups. 7. Energetics of adenine binding with model receptors.
111:1090-1094.
1989
-
N-h bond length determinations and implications for the gramicidin channel conformation and dynamics from n-15-h-1 dipolar interactions.
111:1910-1912.
1989
-
Neutron-diffraction structure-analysis of a hexanuclear copper hydrido complex, h6cu6 p(para-tolyl)3 6 - an unexpected finding.
111:3472-3473.
1989
-
New chiral auxiliaries for thermal cycloadditions.
111:9238-9240.
1989
-
Sequence-selective hydrolysis of duplex DNA by an oligonucleotide-directed nuclease.
111:8523-8525.
1989
-
Stereospecific hydrolysis of alkyl esters by antibodies.
111:5961-5962.
1989
-
Studies of protein hydration in aqueous-solution by direct NMR observation of individual protein-bound water-molecules.
111:1871-1875.
1989
-
Synthesis and characterization of the "chiral wall" porphyrin: a chemically robust ligand for metal-catalyzed asymmetric epoxidations.
111:9116-9117.
1989
-
Synthesis of the abc ring-system of brevetoxin-b.
111:6666-6675.
1989
-
Synthesis of the brevetoxin-b ijk ring-system.
111:6682-6690.
1989
-
Synthesis of the fg ring-system of brevetoxin-b.
111:6676-6682.
1989
-
Synthetic studies on the dioxepane region of brevetoxin-b - new synthetic technology for the construction of oxepanes and synthesis of a model for the cdef ring skeleton of brevetoxin-b.
111:4136-4137.
1989
-
Total synthesis and evaluation of (+/-)-N-(tert-butyloxycarbonyl)-CBI, (+/-)-CBI-CDPI1, and (+/-)-CBI-CDPI2 - CC-1065 functional agents incorporating the equivalent 1,2,9,9a-tetrahydrocycloprop 1,2-c benz 1,2-e indol-4-one (CBI) left-hand subunit.
111:6461-6463.
1989
-
Use of a recombinant bacterial fructose-1,6-diphosphate aldolase in aldol reactions - preparative syntheses of 1-deoxynojirimycin, 1-deoxymannojirimycin, 1,4-dideoxy-1,4-imino-d-arabinitol, and fagomine.
111:3924-3927.
1989
-
A hybrid sequence-selective ribonuclease S.
110:6592-6594.
1988
-
A new class of chelating agents.
110:5192-5193.
1988
-
A practical and enantioselective synthesis of glycosphingolipids and related-compounds - total synthesis of globotriaosylceramide (gb3).
110:7910-7912.
1988
-
A search for peptide ligase: cosolvent-mediated conversion of proteases to esterases for irreversible synthesis of peptides.
110:5162-5166.
1988
-
Allosteric cooperativity and transport: studies in a circulating system.
110:7140-7143.
1988
-
Aluminum dichloride and dibromide - preparation, spectroscopic (including matrix-isolation) study, reactions, and role (together with alkyl(aryl)aluminum monohalides) in the preparation of organo-aluminum compounds.
110:3231-3238.
1988
-
An antibody-catalyzed Claisen rearrangement.
110:4841-4842.
1988
-
Antibody catalysis approaching the activity of enzymes.
110:2282-2286.
1988
-
Antibody catalysis in reverse micelles.
110:8713-8714.
1988
-
Antibody catalysis of bimolecular amide formation.
110:4835-4837.
1988
-
Asymmetric dihydroxylation via ligand-accelerated catalysis.
110:1968-1970.
1988
-
Broken symmetry analysis of spin coupling in iron sulfur clusters.
110:1001-1005.
1988
-
Chemistry of amphotericin-b - degradation studies and preparation of amphoteronolide-b.
110:4660-4672.
1988
-
Clean tocsy for h-1 spin system-identification in macromolecules.
110:7870-7872.
1988
-
Convergent functional groups. 5. Ternary complexes in the molecular recognition of beta-arylethylamines.
110:923-927.
1988
-
Convergent functional groups: catalysis of hemiacetal cleavage in a synthetic molecular cleft.
110:983-984.
1988
-
Cyclic conjugated enediynes related to calicheamicins and esperamicins - calculations, synthesis, and properties.
110:4866-4868.
1988
-
DNA cleavage by a synthetic mimic of the calicheamicin esperamicin class of antibiotics.
110:7247-7248.
1988
-
Enzymes in carbohydrate synthesis - n-acetylneuraminic acid aldolase catalyzed-reactions and preparation of n-acetyl-2-deoxy-d-neuraminic acid-derivatives.
110:6481-6486.
1988
-
Heteronuclear filters for two-dimensional h-1-NMR - identification of the metal-bound amino-acids in metallothionein and observation of small heteronuclear long-range couplings.
110:2388-2393.
1988
-
Lipase-catalyzed irreversible transesterifications using enol esters as acylating reagents - preparative enantioselective and regioselective syntheses of alcohols, glycerol derivatives, sugars, and organometallics.
110:7200-7205.
1988
-
Modification of proteases to esterases for peptide-synthesis - methylchymotrypsin.
110:3709-3710.
1988
-
Molecular recognition: hydrogen bonding and aromatic stacking converge to bind cytosine derivatives.
110:3327-3328.
1988
-
Molecular recognition: multipoint contacts with new sizes and shapes.
110:6575-6577.
1988
-
N,N'-dibenzyl-N,N'-ethylenetartramide: a rationally designed chiral auxiliary for the allylboration reaction.
110:3979-3982.
1988
-
Novel chemistry of dithiatopazine.
110:4868-4869.
1988
-
Photosensitized cleavage of a thymine dimer by an antibody.
110:7888-7890.
1988
-
Site-selective cleavage of RNA by a hybrid enzyme.
110:1614-1615.
1988
-
Stereoelectronic effects and the active site of the serine proteases.
110:5908-5909.
1988
-
Total synthesis of (+)-CC-1065 and ent-(-)-CC-1065.
110:1321-1323.
1988
-
Total synthesis of (+/-)-n-2-(phenylsulfonyl)-cpi, (+/-)-cc-1065, (+)-cc-1065, ent-(-)-cc-1065, and the precise, functional agents (+/-)-cpi-cdpi2, (+)-cpi-cdpi2, and (-)-cpi-cdpi2 (+/-)-(3br-star,4as-star)-deoxy-cc-1065, (+)-(3br,4as)-deoxy-cc-1065, and (-)-(3bs,4ar)-deoxy-cc-1065.
110:4796-4807.
1988
-
Total synthesis of amphotericin-b .3. The final stages.
110:4696-4705.
1988
-
Total synthesis of amphoteronolide-b and amphotericin-b .1. Strategy and stereocontrolled construction of key building-blocks.
110:4672-4685.
1988
-
Total synthesis of amphoteronolide-b and amphotericin-b .2. Total synthesis of amphoteronolide-b.
110:4685-4696.
1988
-
Total synthesis of linear polyprenoids .3. Syntheses of ubiquinones via palladium-catalyzed oligomerization of monoterpene monomers.
110:4356-4362.
1988
-
Vicinal diol cyclic sulfates - like epoxides only more reactive.
110:7538-7539.
1988
-
A highly stereoselective total synthesis of the natural enantiomer of olivin.
109:7575-7577.
1987
-
Applications of tartrate ester modified allylic boronates in organic-synthesis: an efficient, highly stereoselective synthesis of the C19-C29 segment of rifamycin S.
109:953-955.
1987
-
Catalytic antibodies.
109:2174-2176.
1987
-
Catalytic asymmetric epoxidation and kinetic resolution - modified procedures including insitu derivatization.
109:5765-5780.
1987
-
Convergent functional groups. 3. A molecular cleft recognizes substrates of complementary size, shape, and functionality.
109:2426-2431.
1987
-
Convergent functional groups. 4. Recognition and transport of amino acids across a liquid membrane.
109:2432-2434.
1987
-
Diels-alder reactions of heterocyclic azadienes - total synthesis of pde-i, pde-ii, and pde-i dimer methyl-ester.
109:2717-2727.
1987
-
Dithiatopazine - the 1st stable 1,2-dithietane.
109:3801-3802.
1987
-
Inhibition of the hydrolysis of para-(dimethylamino)benzoyl fluoride by potassium fluoride.
109:3160-3161.
1987
-
Kinetic-studies on 1-1 electron-transfer reactions involving blue copper proteins .15. The reactivity of anabaena-variabilis plastocyanin with inorganic complexes and related NMR-studies.
109:6443-6449.
1987
-
Molecular recognition: Watson-Crick, Hoogsteen, and bifurcated hydrogen bonding in a model for adenine recognition.
109:6866-6867.
1987
-
Molecular recognition: hydrogen bonding and stacking interactions stabilize a model for nucleic acid structure.
109:5033-5035.
1987
-
Molecular recognition: new shapes for asymmetric microenvironments.
109:4119-4120.
1987
-
Molecular recognition: size and shape specificity in the binding of dicarboxylic acids.
109:3474-3475.
1987
-
Nucleophilic additions to thionolactones - new synthetic technology for the construction of medium-ring and large-ring ethers.
109:2504-2506.
1987
-
Protein-structure and interactions by combined use of sequential NMR assignments and isotope labeling.
109:1090-1092.
1987
-
Resonance raman-spectra of the 2fe-2s clusters of the rieske protein from thermus and phthalate dioxygenase from pseudomonas.
109:1559-1561.
1987
-
Site-selective observation of nuclear overhauser effects in proteins via isotopic labeling.
109:1591-1593.
1987
-
Stereocontrolled construction of key building-blocks for the total synthesis of amphoteronolide-b and amphotericin-b.
109:2205-2208.
1987
-
Total synthesis of amphotericin-b.
109:2821-2822.
1987
-
Total synthesis of amphoteronolide-b.
109:2208-2210.
1987
-
Triphenylsilyl perchlorate revisited: silicon-29 and chlorine-35 NMR spectroscopy and x-ray crystallography showing covalent nature in both solution and the solid state. Difficulties in observing long-lived silyl cations in the condensed state.
109:5123-5126.
1987
-
Unexpected diversity in the coordination chemistry of tartrate esters with titanium(iv).
109:1279-1282.
1987
-
Bridging of macrocycles to bicycles - new synthetic technology for the construction of cis-fused and trans-fused oxopolycyclic systems.
108:6800-6802.
1986
-
C-C activation of organic small ring compounds by rearrangement of cycloalkylhydridorhodium complexes to rhodacycloalkanes - synthesis of metallacyclobutanes, including one with a tertiary M-C bond, by nucleophilic-addition to p-allyl complexes.
108:7346-7355.
1986
-
Chemo-, regio-, and diastereoselective alkylation via Lewis acid promoted substitutions of sulfones.
108:1098-1100.
1986
-
Combined chemical and enzymatic-synthesis of sialyloligosaccharides and characterization by 500-mhz h-1 and c-13 NMR-spectroscopy.
108:2068-2080.
1986
-
Convergent functional groups provide a measure of stereoelectronic effects at carboxyl oxygen.
108:6068-6069.
1986
-
Diisopropyl tartrate modified (E)-crotylboronates: highly enantioselective propionate (E)-enolate equivalents.
108:294-296.
1986
-
Enzymatic aldol condensation isomerization as a route to unusual sugar-derivatives.
108:7812-7818.
1986
-
Enzyme-catalyzed regioselective deacylation of protected sugars in carbohydrate synthesis.
108:6421-6422.
1986
-
Highly chemoselective palladium-catalyzed conjugate reduction of alpha,beta-unsaturated carbonyl-compounds with silicon hydrides and zinc-chloride cocatalyst.
108:7314-7325.
1986
-
Isomerization of the hydridoalkylrhodium complexes formed on oxidative addition of rhodium to alkane C-H bonds - evidence for the intermediacy of h-2-alkane complexes.
108:7332-7346.
1986
-
Molecular recognition: ionic and aromatic stacking interactions bind complementary functional groups in a molecular cleft.
108:5637-5638.
1986
-
Multiple-quantum-filtered two-dimensional correlated NMR-spectroscopy of proteins.
108:6482-6492.
1986
-
New synthetic technology for the construction of oxocenes.
108:2468-2469.
1986
-
Organic-synthesis with enzymes .3. Tbadh-catalyzed reduction of chloro ketones - total synthesis of (+)-(s,s)-(cis-6-methyltetrahydropyran-2-yl)acetic acid - a civet constituent.
108:3474-3480.
1986
-
Oxygenation of styrene by cytochrome-p-450 model system - a mechanistic study.
108:2588-2594.
1986
-
Regioselective phosphoranylation and cyclodehydration of triols with diethoxytriphenylphosphorane.
108:7681-7685.
1986
-
Simplification of two-dimensional h-1-NMR spectra using an x-filter.
108:6162-6167.
1986
-
Slow complexation rates of crown ethers: what's taking so long?.
108:5011-5012.
1986
-
Stereochemistry of the reactions of substituted allylboronates with chiral aldehydes: factors influencing aldehyde diastereofacial selectivity.
108:3422-3434.
1986
-
Stereospecific 1,2-migrations in carbohydrates - stereocontrolled synthesis of alpha-2-deoxyglycoside beta-2-deoxyglycoside.
108:2466-2467.
1986
-
Thermal-reactions of cyclopropenone ketals - application of the cycloaddition reactions of delocalized singlet vinylcarbenes - 3-carbon 1,1-dipoles 1,3-dipoles - an alternative synthesis of deacetamidocolchiceine - formal total synthesis of colchicine.
108:6713-6719.
1986
-
Thermal-reactions of cyclopropenone ketals - key mechanistic features and scope of the cycloaddition reactions of delocalized singlet vinylcarbenes - 3-carbon 1,1-dipoles 1,3-dipoles.
108:6695-6713.
1986
-
Thermostable enzymes in organic-synthesis .2. Asymmetric reduction of ketones with alcohol-dehydrogenase from thermoanaerobium-brockii.
108:162-169.
1986
-
Allosteric effects in organic chemistry: binding cooperativity in a model for subunit interactions.
107:7481-7487.
1985
-
Binding forces and catalysis. The use of bipyridyl-metal chelation to enhance reaction rates.
107:7487-7493.
1985
-
Convergent functional groups: synthetic and structural studies.
107:7476-7481.
1985
-
Diastereoselective and enantioselective aldehyde addition-reactions of 2-allyl-1,3,2-dioxaborolane-4,5-dicarboxylic esters, a useful class of tartrate ester modified allylboronates.
107:8186-8190.
1985
-
Diethoxytriphenylphosphorane: a mild, regioselective cyclodehydrating reagent for conversion of diols to cyclic ethers. Stereochemistry, synthetic utility, and scope.
107:5210-5219.
1985
-
Enzymatic vs fermentative synthesis - thermostable glucose-dehydrogenase catalyzed regeneration of nad(p)h for use in enzymatic-synthesis.
107:4028-4031.
1985
-
Enzymatic-synthesis of unusual sugars - galactose-oxidase catalyzed stereospecific oxidation of polyols.
107:2997-2999.
1985
-
Epoxidation of olefins by cytochrome-p-450 model compounds - kinetics and stereochemistry of oxygen atom transfer and origin of shape selectivity.
107:2000-2005.
1985
-
Exchange of 2-spin order in nuclear magnetic-resonance - separation of exchange and cross-relaxation processes.
107:6440-6446.
1985
-
Inverse electron demand Diels-Alder reactions of heterocyclic azadienes - formal total synthesis of streptonigrin.
107:5745-5754.
1985
-
Mechanism of oxygen atom transfer from high valent iron porphyrins to olefins - implications to the biological epoxidation of olefins by cytochrome-p-450.
107:4343-4345.
1985
-
Models for ferredoxins: electronic structures of iron-sulfur clusters with one, two, and four iron atoms.
107:3418-3426.
1985
-
Molecular recognition: three-point binding leads to a selective receptor for aromatic amino acids.
107:6738-6739.
1985
-
Polypeptide metal cluster connectivities in metallothionein-2 by novel h-1-cd-113 heteronuclear two-dimensional NMR experiments.
107:6847-6851.
1985
-
Steady-state kinetic-studies of superoxide dismutases - properties of the iron containing protein from escherichia-coli.
107:3295-3304.
1985
-
Stereocontrolled total synthesis of lipoxins-a.
107:7515-7518.
1985
-
Stereospecific synthesis of rhynchosporosides - a family of fungal metabolites causing scald disease in barley and other grasses.
107:5556-5558.
1985
-
Synthetic receptors: size and shape-recognition within a molecular cleft.
107:6736-6738.
1985
-
Total synthesis of elfamycins - aurodox and efrotomycin .1. Strategy and construction of key intermediates.
107:1691-1694.
1985
-
Total synthesis of elfamycins - aurodox and efrotomycin .2. Coupling of key intermediates and completion of the synthesis.
107:1695-1698.
1985
-
Trichothecene metabolism studies: isolation and structure determination of 15-acetyl-3α-(1'β-D-glucopyranosiduronyl)scirpen-3,4β,15-triol.
107:3354-3355.
1985
-
A general and stereocontrolled total synthesis of leukotriene-b4 and analogs.
106:3548-3551.
1984
-
Crystal-structures of 2 titanium tartrate asymmetric epoxidation catalysts.
106:6430-6431.
1984
-
Effective, thermal 3-carbon + 2-carbon cycloaddition for cyclopentenone formation - formal 1,3-dipolar cycloaddition of cyclopropenone ketals.
106:805-807.
1984
-
Electronic structure, magnetic properties, ESR, and optical spectra for 2-Fe ferredoxin models by LCAO-X alpha valence bond theory.
106:2316-2327.
1984
-
Epoxidations with selective peracids.
106:1170-1171.
1984
-
Practical synthesis of oligosaccharides - partial synthesis of avermectin-b1a.
106:4189-4192.
1984
-
Rapid intramolecular rearrangement of a hydridocyclopropylrhodium complex to a rhodacyclobutane - independent synthesis of the metallacycle by addition of hydride to the central carbon-atom of a cationic rhodium p-allyl complex.
106:7272-7273.
1984
-
Sulfones as chemical chameleons. Cyclization via 1,1-dipole synthons.
106:7260-7261.
1984
-
Synthesis of ergot alkaloids from tryptophan.
106:1813-1819.
1984
-
Total synthesis of (-)-ptilocaulin.
106:721-723.
1984
-
Total synthesis of 5(s),15(s)-dihydroxy-6,13-trans-8,11-cis-eicosatetraenoic acid (5,15-dihete) and 8(s),15(s)-dihydroxy-5,11-cis-9,13-trans-eicosatetraenoic acid (8,15-dihete) - 2 novel metabolites of arachidonic-acid.
106:5734-5736.
1984
-
A mild and general-method for the synthesis of o-glycosides.
105:2430-2434.
1983
-
Allosteric effects: an on-off switch.
105:6668-6670.
1983
-
Allosteric effects: structural and thermodynamic origins of binding in cooperativity in a subunit model.
105:6759-6760.
1983
-
Enzyme-catalyzed organic-synthesis - regeneration of deuterated nicotinamide cofactors for use in large-scale enzymatic-synthesis of deuterated substances.
105:5012-5014.
1983
-
Hydrogen-bond length and h-1-NMR chemical-shifts in proteins.
105:5948-5949.
1983
-
Preparation of a mixture of nucleoside triphosphates from yeast rna - use in enzymatic-synthesis requiring nucleoside triphosphate regeneration and conversion to nucleoside diphosphate sugars.
105:115-117.
1983
-
Resonance raman-spectroscopic evidence for a common 3fe-4s structure among proteins containing 3-iron centers.
105:6671-6678.
1983
-
Sequence-specific double-strand cleavage of DNA by bis(EDTA-distamycin.Fe(II) ) and EDTA-bis(distamycin).Fe(II).
105:7748-7750.
1983
-
Sequential assignments for the h-1 and p-31 atoms in the backbone of oligonucleotides by two-dimensional nuclear magnetic-resonance.
105:1652-1653.
1983
-
The mechanism of fe-edta catalyzed superoxide dismutation.
105:5290-5300.
1983
-
Total synthesis of (+/-)-verrucarol.
105:1058-1060.
1983
-
Carbohydrates in organic-synthesis - synthesis of 16-membered-ring macrolide antibiotics .5. Total synthesis of o-mycinosyltylonolide - synthesis of key intermediates.
104:2027-2029.
1982
-
Carbohydrates in organic-synthesis - synthesis of 16-membered-ring macrolide antibiotics .6. Total synthesis of o-mycinosyltylonolide - coupling of key intermediates and macrocyclization.
104:2030-2031.
1982
-
Design and synthesis of a sequence-specific DNA cleaving molecule. (Distamycin-EDTA)iron(II).
104:6861-6863.
1982
-
Direct studies of 1,1-diazenes. Syntheses, infrared and electronic spectra, and kinetics of the thermal decomposition of N-(2,2,6,6-tetramethylpiperidyl)nitrene and N-(2,2,5,5-tetramethylpyrrolidyl)nitrene.
104:766-773.
1982
-
Enzyme-catalyzed transhydrogenation between nicotinamide cofactors and its application in organic-synthesis.
104:3542-3544.
1982
-
General-method for determining absolute-configurations of acyclic allylic alcohols.
104:3775-3776.
1982
-
Photochemistry of 1,1-diazenes. Direct and sensitized photolyses of N-(2,2,5,5-tetramethylpyrrolidyl)nitrene, dl-N-(2,5-diethyl-2,5-dimethylpyrrolidyl)nitrene, and N-(2,2,6,6-tetramethylpiperidyl)nitrene.
104:6660-6668.
1982
-
Soret-excited resonance raman-spectrum of (carbon monoxy)leghemoglobin - assignment of nu-fe-co.
104:626-627.
1982
-
Stereochemical aspects of the intramolecular Diels-Alder reactions of deca-2,7,9-trienoate esters. 3. Thermal, Lewis acid-catalyzed, and asymmetric cyclizations.
104:2269-2283.
1982
-
Synthesis of saccharides and related polyhydroxylated natural-products .3. Efficient conversion of 2,3-erythro-aldoses to 2,3-threo-aldoses.
104:3515-3516.
1982
-
Synthesis of saccharides and related polyhydroxylated natural-products .4. Alpha-d-c-glycopyranoside and beta-d-c-glycopyranoside (2,6-dialkyl-substituted tetrahydropyrans).
104:6468-6470.
1982
-
The endiandric acid cascade - electrocyclizations in organic-synthesis .1. Stepwise, stereocontrolled total synthesis of endiandric acid-a and acid-b.
104:5555-5557.
1982
-
The endiandric acid cascade - electrocyclizations in organic-synthesis .2. Stepwise, stereocontrolled total synthesis of endiandric acids-c-acid-g.
104:5557-5558.
1982
-
The endiandric acid cascade - electrocyclizations in organic-synthesis .3. Biomimetic approach to endiandric acids-a-acid-g - synthesis of precursors.
104:5558-5560.
1982
-
The endiandric acid cascade - electrocyclizations in organic-synthesis .4. Biomimetic approach to endiandric acids-a-acid-g - total synthesis and thermal studies.
104:5560-5562.
1982
-
The mechanism of specific acylation of the active-site of alpha-chymotrypsin by n-acylimidazoles.
104:3569-3576.
1982
-
Asymmetric epoxidation provides shortest routes to 4 chiral epoxy alcohols which are key intermediates in syntheses of methymycin, erythromycin, leukotriene c-1, and disparlure.
103:464-465.
1981
-
Buildup rates of the nuclear overhauser effect measured by two-dimensional proton magnetic-resonance spectroscopy - implications for studies of protein conformation.
103:3654-3658.
1981
-
Enzyme-catalyzed organic-synthesis - nad(p)h cofactor regeneration by using glucose-6-phosphate and the glucose-6-phosphate-dehydrogenase from leuconostoc-mesenteroides.
103:4890-4899.
1981
-
Enzyme-catalyzed organic-synthesis - nad(p)h regeneration using dihydrogen and the hydrogenase from methanobacterium-thermoautotrophicum.
103:6227-6228.
1981
-
Epoxy alcohol rearrangements - hydroxyl-mediated delivery of lewis acid promoters.
103:462-464.
1981
-
Intramolecular Diels-Alder reactions: the angularly methylated trans-perhydroindan ring system.
103:6696-6704.
1981
-
Kinetic resolution of racemic allylic alcohols by enantioselective epoxidation - a route to substances of absolute enantiomeric purity.
103:6237-6240.
1981
-
Magnetic studies and the crystal and molecular-structure of enh2 v(hedta-h) 2.2h2o - a novel di-mu-alcoxy-bridged dimer of 7-coordinate v(iii).
103:5511-5517.
1981
-
Organoselenium-based synthesis of oxygen-containing prostacyclins.
103:3480-3485.
1981
-
Organoselenium-based synthesis of sulfur-containing prostacyclins.
103:3486-3497.
1981
-
Photochemistry of a 1,1-diazene, N-(2,2,5,5-tetramethylpyrrolidinyl)nitrene.
103:1563-1564.
1981
-
Studies on the total synthesis of chlorothricolide: stereochemical aspects of the intramolecular Diels-Alder reactions of methyl undeca-2,8,10-trienoates.
103:5200-5211.
1981
-
Synthesis of (5z)-6,9-thiaprostacyclins and (5e)-6,9-thiaprostacyclins.
103:3472-3480.
1981
-
Synthesis of 16-membered-ring macrolide antibiotics .3. Carbomycin-b and leucomycin-a3 - retrosynthetic studies.
103:1222-1224.
1981
-
Synthesis of 16-membered-ring marcolide antibiotics .4. Carbomycin-b and leucomycin-a3 - total synthesis of cyclic key intermediate.
103:1224-1226.
1981
-
Total synthesis of ionophore antibiotic x-14547a .1. Enantioselective synthesis of the tetrahydropyran and tetrahydroindan building-blocks.
103:6967-6969.
1981
-
Total synthesis of ionophore antibiotic x-14547a .2. Coupling of the tetrahydropyran and tetrahydroindan systems and construction of the butadienyl and ketopyrrole moieties.
103:6969-6971.
1981
-
Allosteric effects. Remote control of ion transport selectivity.
102:4853-4854.
1980
-
Asymmetric induction in the reaction of osmium-tetroxide with olefins.
102:4263-4265.
1980
-
Carbocyclic thromboxane-a2.
102:1404-1409.
1980
-
Does substrate rather than protein provide the catalyst for alpha-proton abstraction in aldolase.
102:3923-3927.
1980
-
Electronic structure of 2-Fe ferredoxin models by X alpha valence bond theory.
102:4279-4282.
1980
-
Olefin epoxidation with alpha-substituted hydroperoxides.
102:5602-5605.
1980
-
On binding in subunit systems.
102:7398-7400.
1980
-
Phenylselenoetherification - a highly efficient cyclization process for the synthesis of o-heterocycles and s-heterocycles.
102:3784-3793.
1980
-
Practical enzymatic syntheses of ribulose 1,5-bisphosphate and ribose 5-phosphate.
102:7938-7939.
1980
-
Synthesis and direct spectroscopic observation of N-(2,2,5,5-tetramethylpyrrolidyl)nitrene: comparison of 5-membered and 6-membered cyclic 1,1-dialkyldiazenes.
102:878-880.
1980
-
The first practical method for asymmetric epoxidation.
102:5974-5976.
1980
-
Total synthesis of (+/-)-dendrobine.
102:1390-1404.
1980
-
Total synthesis of (+/-)-zoapatanol.
102:6611-6612.
1980
-
Total synthesis of rugulovasines.
102:5426-5427.
1980
-
6,9-pyridazaprostacyclin and derivatives: the first "aromatic" prostacyclins.
101:766-768.
1979
-
Allosteric effects in organic chemistry. Site-specific binding.
101:4333-4337.
1979
-
On the rate of site-site interactions in functionalized polystyrenes.
101:737.
1979
-
Phenylselenolactonization and phenylsulfenolactonization - 2 highly efficient and synthetically useful cyclization procedures.
101:3884-3892.
1979
-
Selective naked-cluster cryophotochemistry and SCF-X alpha-SW calculations for Cu2 and Ag2.
101:3504-3511.
1979
-
Chemistry of singlet oxygen. 29. A specific three-phase "Kautsky test" for singlet oxygen.
100:7770-7771.
1978
-
Dynamics of tautomerization of formycin.
100:3957-3958.
1978
-
On binding to transition states and ground states: remote catalysis.
100:4315-4316.
1978
-
Organoselenium-induced ring closures - sulfur-containing prostacyclins - stereoselective synthesis of cyclic alpha,beta-unsaturated sulfoxides, sulfones, and sulfides and synthesis of 6,9-sulfoxa-5(e)-and-5(z)-prostacyclin, 6,9-sulfo-5(e)-and-5(z)-prostacyclin, 6,9-sulfo-6alpha-and-6beta-4(e)-isoprostacyclin, and 6,9-thiaprostacycline.
100:2567-2570.
1978
-
Osmium-catalyzed vicinal oxyamination of olefins by n-chloro-n-argentocarbamates.
100:3596-3598.
1978
-
Steric steering with supported palladium catalysts.
100:7779-7781.
1978
-
The first d0 metallooxaziridines. Amination of olefins.
100:7061-7063.
1978
-
The three-phase test: intermediates in phosphate transfer reactions.
100:8113-8117.
1978
-
Total synthesis of (+/-)-dendrobine.
100:3599-3601.
1978
-
Total synthesis of erythromycins .3. Stereoselective routes to intermediates corresponding to c(1) to c(9) and c(10) to c(13) fragments of erythronolide-b.
100:4618-4620.
1978
-
Total synthesis of erythromycins .4. Total synthesis of erythronolide-b.
100:4620-4622.
1978
-
Transient proton-proton overhauser effects in horse ferrocytochrome-c.
100:7094-7096.
1978
-
6,9-thiaprostacyclin. A stable and biologically potent analogue of prostacyclin (PGI2).
99:7736-7738.
1977
-
Allylic oxidation of olefins by catalytic and stoichiometric selenium dioxide with tert-butyl hydroperoxide.
99:5526-5528.
1977
-
Catalysis of superoxide dismutation by iron-ethylenediaminetetraacetic acid complexes - mechanism of reaction and evidence for direct formation of an iron(iii)-ethylenediaminetetraacetic acid peroxo complex from reaction of superoxide with "iron(ii)-ethylenediaminetetraacetic acid.
99:5220-5222.
1977
-
Chiral hydroxamic acids as ligands in vanadium catalyzed asymmetric epoxidation of allylic alcohols by tert-butyl hydroperoxide.
99:1990-1992.
1977
-
Chromyl chloride oxidations of olefins - possible role of organometallic intermediates in oxidations of olefins by oxo transition-metal species.
99:3120-3128.
1977
-
Organic chemistry on the solid phase. Site-site interactions on functionalized polystyrene.
99:625-626.
1977
-
Phenylselenolactonization - extremely mild and synthetically useful cyclization process.
99:3185-3187.
1977
-
Synthesis of dioxobis(tert-alkylimido)osmium(viii) and oxotris(tert-alkylimido)osmium(viii) complexes - stereospecific vicinal diamination of olefins.
99:3420-3426.
1977
-
Allylic amination of olefins and acetylenes by imido selenium-compounds.
98:269-271.
1976
-
Osmium catalyzed vicinal hydroxylation of olefins by tert-butyl hydroperoxide under alkaline conditions.
98:1986-1987.
1976
-
Selenium dioxide oxidation of ketones and aldehydes - evidence for intermediacy of beta-ketoseleninic acids.
98:300-301.
1976
-
Kinetics and equilibria of reaction of pyridoxal 5'-phosphate with ethylenediamine to form schiff-bases and cyclic geminal diamines - evidence for kinetically competent geminal diamine intermediates in transimination sequences.
97:6530-6539.
1975
-
New probes for the study of acylation reactions.
97:4407-4408.
1975
-
Oxidation of alcohols to aldehydes by reagents derived from chromyl chloride.
97:5927-5928.
1975
-
The three phase test for reaction intermediates. Evidence for monomeric metaphosphate.
97:3221-3222.
1975
-
The three-phase test for reaction intermediates. Metaphosphates.
97:1591-1592.
1975
-
The three-phase test for reaction intermediates. Nucleophilic catalysis and elimination reactions.
97:454-455.
1975
-
Three-phase test. Detection of free cyclobutadiene.
97:3453-3456.
1975
-
Efficient and mild lactonization method for synthesis of macrolides.
96:5614-5616.
1974
-
Intermolecular proton-transfer reaction between base and phosphate moieties of mononucleotides in solution.
96:2609-2611.
1974
-
Mechanism of the carbodiimide reaction. II. Peptide synthesis on the solid phase.
96:1606-1607.
1974
-
The three-phase test for reactive intermediates. Cyclobutadiene.
96:7112-7114.
1974
-
An improved method for the study of reaction intermediates. The mechanism of peptide synthesis mediated by carbodiimides.
95:4052-4053.
1973
-
Diastereomeric monocyclic diallenes. Synthesis and properties of the diastereomeric 3,4,9,10-cyclododecatetraene-1,7-diones and 3,4,10,11-cyclotetradecatetraene-1,8-diones.
95:4582-4592.
1973
-
Electrophilic and nucleophilic organoselenium reagents. New routes to alpha, beta-unsaturated carbonyl compounds.
95:6137-6139.
1973
-
High stereo- and regioselectivities in the transition metal catalyzed epoxidations of olefinic alcohols by tert-butyl hydroperoxide.
95:6136-6137.
1973
-
Reorientational correlation-functions obtained from Raman line shapes.
95:1391-1398.
1973
-
Selenium dioxide oxidations of olefins - trapping of allylic seleninic acid intermediate as a seleninolactone.
95:7917-7919.
1973
-
Lower valent tungsten halides. New class of reagents for deoxygenation of organic molecules.
94:6538-6540.
1972
-
Mechanism of epoxidation of olefins by covalent peroxides of molybdenum(vi).
94:295-296.
1972
-
Selenium dioxide oxidation of olefins. Evidence for intermediacy of allylseleninic acids.
94:7154-7155.
1972
-
Permanganate in acetic anhydride. Alpha-diketones directly from olefins.
93:3303-3304.
1971
-
D,l-malabaricanediol. The first cyclic natural product derived from squalene in a nonenzymic process.
92:6999-7001.
1970
-
Magnetic resonance and mass spectrum of pi-cyclopentadienyl-pi-cycloheptatrienylvanadium. Mass spectral rearrangement to bis(benzene)vanadium.
92:5100-5104.
1970
-
Peptide racemization mechanism. A kinetic isotope effect as a means of distinguishing enolization from oxazolone formation.
92:5792-5793.
1970
-
Racemization during peptide couplings using the mixed anhydride, N-hydroxysuccinimide ester, 8-hydroxyquinoline ester, and acyl azide methods.
92:4756-4757.
1970
-
Mechanism of the titanium-promoted deoxygenative coupling of allyl and benzyl alcohols to hydrocarbons.
91:1552-1554.
1969
-
Terpene terminal epoxides. Skeletal rearrangement accompanying bicyclization of squalene 2,3-oxide.
91:1848-1849.
1969
-
Enzymic cyclization of 15-norsqualene 2,3-oxide.
90:3284-3286.
1968
-
One-step synthesis of 1,5-dienes involving reductive coupling of allyl alcohols.
90:209-210.
1968
-
An investigation of water-urea and water-urea-polyethylene glycol interactions.
89:442-446.
1967
-
Biological activities of some terminally modified squalene and squalene 2,3-oxide analogs.
89:3920-3922.
1967
-
Dipole moments in relation to configuration of polypeptide chains.
89:6807-6813.
1967
-
Enzymic cyclization of trans,trans,trans-18,19-dehydrosqualene 2,3-oxide.
89:7150-7151.
1967
-
Equilibrium measurements of the binding of cytidine 3'-phosphate to ribonuclease.
87:4665-4669.
1965
-
Purification and characterization of sheep prolactin.
83:3717-3719.
1961
Identity
International Standard Serial Number (ISSN)
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