Journal of the American Chemical Society

articles

2-Sulfonylpyridines as Tunable, Cysteine-Reactive Electrophiles. 142:8972-8979. 2020
Achieving Site-Selectivity for C-H Activation Processes Based on Distance and Geometry: A Carpenter's Approach. 142:10571-10591. 2020
Catalytic α-Hydroarylation of Acrylates and Acrylamides via an Interrupted Hydrodehalogenation Reaction. 142:10477-10484. 2020
Chalcogen Bonding and Hydrophobic Effects Force Molecules into Small Spaces. 142:5876-5883. 2020
Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect Splicing. 142:8706-8727. 2020
Enantiodivergent Formation of C-P Bonds: Synthesis of P-Chiral Phosphines and Methylphosphonate Oligonucleotides. 142:5785-5792. 2020
Iridium(I)-Catalyzed α-C(sp 3)-H Alkylation of Saturated Azacycles. 142:5117-5125. 2020
Isotopically directed symmetry breaking and enantioenrichment in attrition-enhanced deracemization. 142:3873-3879. 2020
Ligand-Enabled Monoselective β-C(sp 3)-H Acyloxylation of Free Carboxylic Acids Using a Practical Oxidant. 142:6769-6776. 2020
Nanopore sequencing of an expanded genetic alphabet reveals high-fidelity replication of a predominantly hydrophobic unnatural base pair. 142:2110-2114. 2020
Pd(II)-Catalyzed Enantioselective γ-C(sp 3)-H Functionalizations of Free Cyclopropylmethylamines. 142:12015-12019. 2020
Radical reactions in cavitands unveil the effects of affinity on dynamic supramolecular systems. 142:2396-2403. 2020
Selection of aptamers with large hydrophobic 2'-substituents. 142:2125-2128. 2020
Semisynthesis of a Bacterium with Non-canonical Cell-Wall Cross-Links. 142:10910-10913. 2020
Sulfur(VI) Fluoride Exchange (SuFEx)-Enabled High-Throughput Medicinal Chemistry. 142:10899-10904. 2020
Synthesis of (-)-Picrotoxinin by Late-Stage Strong Bond Activation. 142:11376-11381. 2020
Targeted Degradation of the Oncogenic MicroRNA 17-92 Cluster by Structure-Targeting Ligands. 142:6970-6982. 2020
Total Synthesis of (-)-Maximiscin. 142:8608-8613. 2020
Trisaccharide Sulfate and Its Sulfonamide as an Effective Substrate and Inhibitor of Human Endo-O-sulfatase-1. 142:5282-5292. 2020
Two-Phase Synthesis of Taxol. 142:10526-10533. 2020
δ-C-H mono- and dihalogenation of alcohols. 142:2766-2770. 2020
11-step total synthesis of teleocidins B-1-6-4. 141:1494-1497. 2019
A chlorine-atom-controlled terminal-epoxide-initiated bicyclization cascade enables a synthesis of the potent cytotoxins haterumaimides J and K. 141:9202-9206. 2019
A designed small molecule inhibitor of a non-coding RNA sensitizes HER2 negative cancers to herceptin. 141:2960-2974. 2019
A radical approach to anionic chemistry: synthesis of ketones, alcohols, and amines. 141:6726-6739. 2019
A sulfonamide sialoside analogue for targeting siglec-8 and -F on immune cells. 141:14032-14037. 2019
Allyl-nickel catalysis enables carbonyl dehydrogenation and oxidative cycloalkenylation of ketones. 141:5669-5674. 2019
An efficient modular one-pot synthesis of heparin-based anticoagulant idraparinux. 141:10309-10314. 2019
Analysis of protein-protein interaction in a single live cell by using a FRET system based on genetic code expansion technology. 141:4273-4281. 2019
Asymmetric total synthesis of arcutinidine, arcutinine, and arcutine. 141:13718-13723. 2019
Benzimidazoles as metal-free and recyclable hydrides for CO2 reduction to formate. 141:272-280. 2019
Catalytic deuterium incorporation within metabolically stable β-amino C-H bonds of drug molecules. 141:14570-14575. 2019
Characterization and crystal structure of a nonheme diiron monooxygenase involved in platensimycin and platencin biosynthesis. 141:12406-12412. 2019
Chemical interventions for the opioid crisis: key advances and remaining challenges. 141:1798-1806. 2019
Chemo-, regio-, diastereo-, and enantioselective palladium allylic alkylation of 1,3-dioxaboroles as synthetic equivalents of α-hydroxyketones. 141:9521-9526. 2019
Concise total synthesis of herqulines B and C. 141:29-32. 2019
Consequence of hapten stereochemistry: an efficacious methamphetamine vaccine. 141:14089-14092. 2019
Controlled cationic polymerization: single-component initiation under ambient conditions. 141:10605-10609. 2019
Convergent total synthesis of principinol D, a rearranged kaurane diterpenoid. 141:8088-8092. 2019
Coupling of DNA circuit and templated reactions for quadratic amplification and release of functional molecules. 141:16288-16295. 2019
Cryptic and stereospecific hydroxylation, oxidation, and reduction in platensimycin and platencin biosynthesis. 141:4043-4050. 2019
Development of a terpene feedstock-based oxidative synthetic approach to the illicium sesquiterpenes. 141:3083-3099. 2019
Direct carbon isotope exchange through decarboxylative carboxylation. 141:774-779. 2019
Direct intermolecular anti-Markovnikov hydroazidation of unactivated olefins. 141:9415-9421. 2019
Discovery of FAHFA-containing triacylglycerols and their metabolic regulation. 141:8798-8806. 2019
Electrochemically driven, Ni-catalyzed aryl amination: scope, mechanism, and applications. 141:6392-6402. 2019
Enantioselective Conia-ene-type cyclizations of alkynyl ketones through cooperative action of B(C6F5)(3), N-alkylamine and a Zn-based catalyst. 141:4199-4203. 2019
Enantioselective synthesis of azamerone. 141:2867-2871. 2019
Enantioselective synthesis of isocarbostyril alkaloids and analogs using catalytic dearomative functionalization of benzene. 141:657-670. 2019
Enantioselective synthesis of α-allyl amino esters via hydrogen-bond-donor catalysis. 141:11414-11419. 2019
Expanding reactivity in DNA-encoded library synthesis via reversible binding of DNA to an inert quaternary ammonium support. 141:9998-10006. 2019
General synthetic approach for the Laurencia family of natural products empowered by a potentially biomimetic ring expansion. 141:7776-7788. 2019
Hemilabile benzyl ether enables γ-C(sp3)-H carbonylation and olefination of alcohols. 141:15494-15497. 2019
Hydroalkylation of olefins to form quaternary carbons. 141:7709-7714. 2019
Identification of the Formycin A biosynthetic gene cluster from streptomyces kaniharaensis illustrates the interplay between biological pyrazolopyrimidine formation and de novo purine biosynthesis. 141:6127-6131. 2019
Impact of stereo- and regiochemistry on energetic materials. 141:12531-12535. 2019
Ipomoeassin F binds Sec61α to inhibit protein translocation. 141:8450-8461. 2019
Monoclonal antibodies for combating synthetic opioid intoxication. 141:10489-10503. 2019
Natural products in the "marketplace": Interfacing synthesis and biology. 141:3332-3346. 2019
Nickel-catalyzed enantioselective hydroarylation and hydroalkenylation of styrenes. 141:3395-3399. 2019
O-GlcNAc engineering of GPCR peptide-agonists improves their stability and in vivo activity. 141:14210-14219. 2019
Oligosaccharide synthesis and translational innovation. 141:3735-3754. 2019
Optimization of replication, transcription, and translation in a semi-synthetic organism. 141:10644-10653. 2019
Palladium-catalyzed dearomative syn-1,4-diamination. 141:163-167. 2019
Programmable artificial cells using histamine-responsive synthetic riboswitch. 141:11103-11114. 2019
Progress toward eukaryotic semisynthetic organisms: translation of unnatural codons. 141:20166-20170. 2019
Rh(III)-catalyzed meta-C-H alkenylation with alkynes. 141:76-79. 2019
Sequential functionalization of meta-C-H and ipso-C-O bonds of phenols. 141:1903-1907. 2019
Single-atom fluorescence switch: a general approach toward visible-light-activated dyes for biological imaging. 141:14699-14706. 2019
Synthesis of (+/-)-idarubicinone via global functionalization of tetracene. 141:10193-10198. 2019
Synthesis of sialidase-resistant oligosaccharide and antibody glycoform containing α2,6-linked 3Fax-Neu5Ac. 141:6484-6488. 2019
Targeting RNA with small molecules to capture opportunities at the intersection of chemistry, biology, and medicine. 141:6776-6790. 2019
The role of protein thermodynamics and primary structure in fibrillogenesis of variable domains from immunoglobulin light chains. 141:13562-13571. 2019
The total synthesis of chalcitrin. 141:4515-4520. 2019
Total synthesis and stereochemical assignment of streptide. 141:17361-17369. 2019
Total synthesis of (+)-arborisidine. 141:7715-7720. 2019
Total synthesis of (+)-granatumine A and related bislactone limonoid alkaloids via a pyran to pyridine interconversion. 141:9191-9196. 2019
Total synthesis of paspaline A and emindole PB enabled by computational augmentation of a transform-guided retrosynthetic strategy. 141:1479-1483. 2019
Toward a synthetic yeast endosymbiont with a minimal genome. 141:13799-13802. 2019
Triarylaminium radical cation promoted coupling of catharanthine with vindoline: diastereospecific synthesis of anhydrovinblastine and reaction scope. 141:14349-14355. 2019
Understanding the activity and enantioselectivity of acetyl-protected aminoethyl quinoline ligands in palladium-catalyzed β-C(sp3)-H bond arylation reactions. 141:16726-16733. 2019
meta C-H arylation of electron-rich arenes: reversing the conventional site selectivity. 141:14870-14877. 2019
"Inverse drug discovery" strategy to identify proteins that are targeted by latent electrophiles as exemplified by aryl fluorosulfates. 140:200-210. 2018
A tool for the import of natural and unnatural nucleoside triphosphates into bacteria. 140:1447-1454. 2018
An oxetane-based polyketide surrogate To probe substrate binding in a polyketide synthase. 140:4961-4964. 2018
Analyte-driven disassembly and turn-on fluorescent sensing in competitive biological media. 140:3500-3504. 2018
Bacterial genome containing chimeric DNA-RNA sequences. 140:11464-11473. 2018
Branch-selective addition of unactivated olefins into imines and aldehydes. 140:16976-16981. 2018
C(alkenyl)-H activation via six-membered palladacycles: catalytic 1,3-diene synthesis. 140:5805-5813. 2018
C-H functionalization of amines via alkene-derived nucleophiles through cooperative action of chiral and achiral lewis acid catalysts: applications in enantioselective synthesis. 140:10593-10601. 2018
Catalytic carbo- and aminoboration of alkenyl carbonyl compounds via five- and six-membered palladacycles. 140:3223-3227. 2018
Catalytic regio- and enantioselective haloazidation of allylic alcohols. 140:15646-15650. 2018
Catalytically active single-chain polymeric nanoparticles: exploring their functions in complex biological media. 140:3423-3433. 2018
Controlled formation and binding selectivity of discrete oligo(methyl methacrylate) stereocomplexes. 140:1945-1951. 2018
Copper-catalyzed electrochemical C-H amination of arenes with secondary amines. 140:11487-11494. 2018
Copper-catalyzed vinylogous aerobic oxidation of unsaturated compounds with air. 140:5300-5310. 2018
Cytochrome P450-catalyzed hydroxylation initiating ether formation in platensimycin biosynthesis. 140:12349-12353. 2018
Design of a DNA-programmed plasminogen activator. 140:15516-15524. 2018
Diprovocims: A new and exceptionally potent class of toll-like receptor agonists. 140:14440-14454. 2018
Direct access to versatile electrophiles via catalytic oxidative cyanation of alkenes. 140:8069-8073. 2018
Discovery and characterization of 1-aminocyclopropane-1-carboxylic acid synthase of bacterial origin. 140:16957-16961. 2018
Divergent synthesis of pyrone diterpenes via radical cross coupling. 140:7462-7465. 2018
Dynamic and responsive DNA-like polymers. 140:13594-13598. 2018
Enantioselective synthesis of oseltamivir phosphate (Tamiflu) via the iron-catalyzed stereoselective olefin diazidation. 140:10619-10626. 2018
Enantioselective synthesis of pyrroloindolines via noncovalent stabilization of indole radical cations and applications to the synthesis of alkaloid natural products. 140:3394-3402. 2018
Enantioselective γ-C(sp3)-H activation of alkyl amines via Pd(II)/Pd(0) catalysis. 140:5322-5325. 2018
Engineering improved antiphosphotyrosine antibodies based on an immunoconvergent binding motif. 140:16615-16624. 2018
Enhancing protein stability with genetically encoded noncanonical amino acids. 140:15997-16000. 2018
Extrinsic tryptophans as NMR probes of allosteric coupling in membrane proteins: application to the A2A adenosine receptor. 140:8228-8235. 2018
Functional replacement of histidine in proteins to generate noncanonical amino acid dependent organisms. 140:3829-3832. 2018
Iron-nickel dual-catalysis: a new engine for olefin functionalization and the formation of quaternary centers. 140:11317-11324. 2018
Ligand-enabled β-C(sp3)-H olefination of free carboxylic acids. 140:10363-10367. 2018
Ligand-enabled γ-C(sp3)-H activation of ketones. 140:3564-3568. 2018
Macrocyclization of interferon-poly(α-amino acid) conjugates significantly improves the tumor retention, penetration, and antitumor efficacy. 140:1170-1178. 2018
Mechanism of the Ullmann biaryl ether synthesis catalyzed by complexes of anionic ligands: Evidence for the reaction of iodoarenes with ligated anionic Cu-I intermediates. 140:793-806. 2018
Mechanistic interrogation of Co/Ni-dual catalyzed hydroarylation. 140:12056-12068. 2018
Mechanistic investigation and multiplexing of liposome-assisted metabolic glycan labeling. 140:3592-3602. 2018
Mixed explicit-implicit solvation approach for modeling of alkane complexation in water-soluble self-assembled capsules. 140:12527-12537. 2018
Modulation of fluorescent protein chromophores to detect protein aggregation with turn-on fluorescence. 140:7381-7384. 2018
Natural product total synthesis: as exciting as ever and here to stay. 140:4751-4755. 2018
Ni-catalyzed regioselective alkylarylation of vinylarenes via C(sp3)–C(sp3)/C(sp3)–C(sp2) bond formation and mechanistic studies. 140:9801-9805. 2018
Ni-catalyzed regioselective β,δ-diarylation of unactivated olefins in ketimines via ligand-enabled contraction of transient nickellacycles: rapid access to remotely diarylated ketones. 140:7782-7786. 2018
Nickel-catalyzed 1,2-diarylation of simple alkenyl amides. 140:17878-17883. 2018
Nickel-catalyzed dearomative trans-1,2-carboamination. 140:4503-4507. 2018
Osmolytes and protein-protein interactions. 140:7441-7444. 2018
Overcoming the limitations of γ, and δ-C-H arylation of amines through ligand development. 140:17884-17894. 2018
Pd(II)-catalyzed enantioselective C(sp(3))-H arylation of free carboxylic acids. 140:6545-6549. 2018
Progress toward a semi-synthetic organism with an unrestricted expanded genetic alphabet. 140:16115-16123. 2018
Promysalin elicits species-selective inhibition of pseudomonas aeruginosa by targeting succinate dehydrogenase. 140:1774-1782. 2018
Remote C-H hydroxylation by an α-ketoglutarate-dependent dioxygenase enables efficient chemoenzymatic synthesis of manzacidin C and proline analogs. 140:1165-1169. 2018
Reprograming the replisome of a semisynthetic organism for the expansion of the genetic alphabet. 140:758-765. 2018
Rhodium-catalyzed B-H bond insertion reactions of unstabilized diazo compounds generated in situ from tosylhydrazones. 140:10663-10668. 2018
Scalable access to arylomycins via C-H functionalization logic. 140:2072-2075. 2018
Secondary photocrosslinking of click hydrogels to probe myoblast mechanotransduction in three dimensions. 140:11585-11588. 2018
Slow dynamics of tryptophan-water networks in proteins. 140:675-682. 2018
Small molecule targeted recruitment of a nuclease to RNA. 140:6741-6744. 2018
SuFEx click chemistry enabled late-stage drug functionalization. 140:2919-2925. 2018
Synergistic bimetallic Ni/Ag and Ni/Cu catalysis for regioselective γ,δ-diarylation of alkenyl ketimines: addressing β-H elimination by in situ generation of cationic Ni(II) catalysts. 140:15586-15590. 2018
Synthesis and mechanochemical activation of ladderene-norbornene block copolymers. 140:12388-12391. 2018
Total Synthesis of Septedine and 7-Deoxyseptedine. 140:9025-9029. 2018
Total synthesis of (-)-xylogranatopyridine B via a palladium-catalyzed oxidative stannylation of enones. 140:2062-2066. 2018
Total synthesis of aplysiasecosterol A. 140:9211-9218. 2018
Total synthesis of hybridaphniphylline B. 140:4227-4231. 2018
Total synthesis of the caged indole alkaloid arboridinine enabled by aza-Prins and metal-mediated cyclizations. 140:919-925. 2018
Total synthesis, biological evaluation, and target identification of rare Abies sesquiterpenoids. 140:17465-17473. 2018
Unprecedented role of hybrid N-glycans as ligands for HIV-1 broadly neutralizing antibodies. 140:5202-5210. 2018
A role for Pd(IV) in catalytic enantioselective C-H functionalization with monoprotected amino acid ligands under mild conditions. 139:9238-9245. 2017
Antimicrobials inspired by nonribosomal peptide synthetase gene clusters. 139:1404-1407. 2017
Assembly of the limonoid architecture by a divergent approach: total synthesis of (±)-andirolide N via (±)-8α-hydroxycarapin. 139:631-634. 2017
CD22 ligands on a natural N-glycan scaffold efficiently deliver toxins to B-lymphoma cells. 139:12450-12458. 2017
Catalytic B-H bond insertion reactions using alkynes as carbene precursors. 139:3784-3789. 2017
Catalytic intermolecular carboamination of unactivated alkenes via directed aminopalladation. 139:11261-11270. 2017
Chemical stabilization of unnatural nucleotide triphosphates for the in vivo expansion of the genetic alphabet. 139:2464-2467. 2017
Chemically controlled epigenome editing through an inducible dCas9 system. 139:11337-11340. 2017
Co-assembly of peptide amphiphiles and lipids into supramolecular nanostructures driven by anion-π interactions. 139:7823-7830. 2017
Concurrent modulation of quantum dot photoluminescence using a combination of charge transfer and Forster resonance energy transfer: competitive quenching and multiplexed biosensing modality. 139:363-372. 2017
Copper-catalyzed dicarbofunctionalization of unactivated olefins by tandem cyclization/cross-coupling. 139:5700-5703. 2017
Covalent capture of aligned self-assembling nanofibers. 139:8044-8050. 2017
Covalent modulators of the vacuolar ATPase. 139:639-642. 2017
Critical analysis of rate constants and turnover frequency in nucleic acid-templated reactions: reaching terminal velocity. 139:1444-1447. 2017
Crystal-phase transitions and photocatalysis in supramolecular scaffolds. 139:6120-6127. 2017
Cu(II)-catalyzed ortho-selective aminomethylation of phenols. 139:12390-12393. 2017
Cyanine conformational restraint in the far-red range. 139:12406-12409. 2017
Defining the structural basis for allosteric product release from E. coli dihydrofolate reductase using NMR relaxation dispersion. 139:11233-11240. 2017
Design of benzoxathiazin-3-one 1,1-dioxides as a new class of irreversible serine hydrolase inhibitors: Discovery of a uniquely selective PNPLA4 inhibitor. 139:7052-7061. 2017
Development of a clinically viable heroin vaccine. 139:8601-8611. 2017
Diverse ortho-C(sp(2))-H functionalization of benzaldehydes using transient directing groups. 139:888-896. 2017
Diverse redoxome reactivity profiles of carbon nucleophiles. 139:5588-5595. 2017
Dynamic ligand exchange as a mechanistic probe in Pd-catalyzed enantioselective C-H functionalization reactions using monoprotected amino acid ligands. 139:18500-18503. 2017
Efficient liver targeting by polyvalent display of a compact ligand for the asialoglycoprotein receptor. 139:3528-3536. 2017
Enantioselective chemical syntheses of the furanosteroids (-)-viridin and (-)-viridiol. 139:6819-6822. 2017
Enantiospecific solvolytic functionalization of bromochlorides. 139:13562-13569. 2017
Enantiospecific total synthesis of the highly strained (-)-presilphiperfolan-8-ol via a Pd-catalyzed tandem cyclization. 139:5007-5010. 2017
Engineering bifunctional antibodies with constant region fusion architectures. 139:18607-18615. 2017
Experimental and computational development of a conformationally flexible template for the meta-C-H functionalization of benzoic acids. 139:10702-10714. 2017
Fe-catalyzed C-C bond construction from olefins via radicals. 139:2484-2503. 2017
Fluorescence turn-on sensing of DNA duplex formation by a tricyclic cytidine analogue. 139:1372-1375. 2017
Frustrated Lewis acid/Brønsted base catalysts for direct enantioselective α-amination of carbonyl compounds. 139:95-98. 2017
Generation of an orthogonal protein-protein interface with a noncanonical amino acid. 139:5728-5731. 2017
Genetically encoded fluorescent probe for detecting sirtuins in living cells. 139:12350-12353. 2017
Glutamine amide flip elicits long distance allosteric responses in the LOV protein vivid. 139:2972-2980. 2017
Heterogeneous-backbone foldamer mimics of zinc finger tertiary structure. 139:7931-7938. 2017
Highly versatile β-C(sp3)-H iodination of ketones using a practical auxiliary. 139:12394-12397. 2017
In vivo structure-activity relationships and optimization of an unnatural base pair for replication in a semi-synthetic organism. 139:11427-11433. 2017
Investigation of trimethyllysine binding by the HP1 chromodomain via unnatural amino acid mutagenesis. 139:17253-17256. 2017
Isolable and readily handled halophosphonium pre-reagents for hydro- and deuteriohalogenation. 139:6329-6337. 2017
Isomer-specific hydrogen bonding as a design principle for bidirectionally quantitative and redshifted hemithioindigo photoswitches. 139:10956-10959. 2017
Ligand-enabled Pd(II)-catalyzed bromination and iodination of C(sp3)-H bonds. 139:5724-5727. 2017
Ligand-enabled meta-selective C-H arylation of nosyl-protected phenethylamines, benzylamines, and 2-aryl anilines. 139:417-425. 2017
Mechanistic insight into the photocontrolled cationic polymerization of vinyl ethers. 139:15530-15538. 2017
Metal ions effectively ablate the action of Botulinum neurotoxin A. 139:7264-7272. 2017
Modular, scalable synthesis of group A streptogramin antibiotics. 139:13304-13307. 2017
Ni-catalyzed regioselective 1,2-dicarbofunctionalization of olefins by intercepting Heck intermediates as imine-stabilized transient metallacycles. 139:10653-10656. 2017
Nickel-catalyzed β,γ-dicarbofunctionalization of alkenyl carbonyl compounds via conjunctive cross-coupling. 139:10657-10660. 2017
Palladium(II)-catalyzed directed anti-hydrochlorination of unactivated alkynes with HCl. 139:5183-5193. 2017
Palladium-catalyzed C(sp(3))-H oxygenation via electrochemical oxidation. 139:3293-3298. 2017
Palladium-catalyzed dearomative syn-1,4-carboamination. 139:17787-17790. 2017
Pd(II)-catalyzed enantioselective C(sp(3))-H borylation. 139:3344-3347. 2017
Peptide macrocyclization inspired by non-ribosomal imine natural products. 139:5233-5241. 2017
Photocontrolled interconversion of cationic and radical polymerizations. 139:10665-10668. 2017
Polymerase chain transcription: exponential synthesis of RNA and modified RNA. 139:9949-9954. 2017
Potassium tert-butoxide-catalyzed dehydrogenative C-H silylation of heteroaromatics: A combined experimental and computational mechanistic study. 139:6867-6879. 2017
Programmable assembly of peptide amphiphile via noncovalent-to-covalent bond conversion. 139:8995-9000. 2017
Quantum chemical modeling of cycloaddition reaction in a self-assembled capsule. 139:15494-15503. 2017
Recombinant macrocyclic lanthipeptides incorporating non-canonical amino acids. 139:11646-11649. 2017
Regulating miRNA-21 biogenesis by bifunctional small molecules. 139:4987-4990. 2017
Residues comprising the enhanced aromatic sequon influence protein N-glycosylation efficiency. 139:12947-12955. 2017
Rh(III)-catalyzed meta-C-H olefination directed by a nitrile template. 139:2200-2203. 2017
Scalable, electrochemical oxidation of unactivated C-H bonds. 139:7448-7451. 2017
Selection of 2'-fluoro-modified aptamers with optimized properties. 139:2892-2895. 2017
Small molecule inhibition of microRNA-210 reprograms an oncogenic hypoxic circuit. 139:3446-3455. 2017
Small molecule recognition triggers secondary and tertiary interactions in DNA folding and hammerhead ribozyme catalysis. 139:9815-9818. 2017
Stereochemistry of endogenous palmitic acid ester of 9-hydroxystearic acid and relevance of absolute configuration to regulation. 139:4943-4947. 2017
Stereocontrolled synthesis of kalihinol C. 139:3647-3650. 2017
Stolonidiol: Synthesis, target identification, and mechanism for choline acetyltransferase activation. 139:5865-5869. 2017
Strain-release heteroatom functionalization: Development, scope, and stereospecificity. 139:3209-3226. 2017
Strained cyclic disulfides enable cellular uptake by reacting with the transferrin receptor. 139:231-238. 2017
Structure-activity relationship and molecular mechanics reveal the importance of ring entropy in the biosynthesis and activity of a natural product. 139:2541-2544. 2017
Supramolecular "Trojan Horse" for nuclear delivery of dual anticancer drugs. 139:2876-2879. 2017
Supramolecular metal-coordination polymers, nets, and frameworks from synthetic coiled-coil peptides. 139:2212-2215. 2017
Synthesis of (+)-pancratistatins via catalytic desymmetrization of benzene. 139:15656-15659. 2017
Synthesis of (-)-11-O-debenzoyltashironin: neurotrophic sesquiterpenes cause hyperexcitation. 139:9637-9644. 2017
Synthesis of Z- or E-trisubstituted allylic alcohols and ethers by kinetically controlled cross-metathesis with a Ru catechothiolate complex. 139:15640-15643. 2017
The origins of dramatic differences in five-membered vs six-membered chelation of Pd(II) on efficiency of C(sp3)-H bond activation. 139:8514-8521. 2017
Total syntheses of (-)-majucin and (-)-jiadifenoxolane A, complex majucin-type illicium sesquiterpenes. 139:17783-17786. 2017
Total syntheses of scaparvins B, C, and D enabled by a Key C-H functionalization. 139:18428-18431. 2017
Total synthesis and stereochemical assignment of delavatine A: Rh-catalyzed asymmetric hydrogenation of indene-type tetrasubstituted olefins and kinetic resolution through Pd catalyzed triflamide-directed C-H olefination. 139:5558-5567. 2017
Total synthesis of (±)-berkeleyone A. 139:1790-1793. 2017
Total synthesis of longeracinphyllin A. 139:14893-14896. 2017
Tridentate directing groups stabilize 6-membered palladacycles in catalytic alkene hydrofunctionalization. 139:15576-15579. 2017
Versatile alkylation of (hetero)aryl iodides with ketones via β-C(sp3)-H activation. 139:16080-16083. 2017
Water dynamics from the surface to the interior of a supramolecular nanostructure. 139:8915-8921. 2017
11-step total synthesis of (-)-maoecrystal V. 138:9425-9428. 2016
11-step total synthesis of araiosamines. 138:14234-14237. 2016
11-step total synthesis of pallambins C and D. 138:7536-7539. 2016
A carbohydrate-derived splice modulator. 138:5063-5068. 2016
A versatile and scalable strategy to discrete oligomers. 138:6306-6310. 2016
Activation of cell-penetrating peptides with Ionpair-π interactions and fluorophiles. 138:11264-11271. 2016
Amide α,β-dehydrogenation using allyl-palladium catalysis and a hindered monodentate anilide. 138:1166-1169. 2016
An evolved orthogonal enzyme/cofactor pair. 138:12451-12458. 2016
Analysis of Loops that Mediate Protein-Protein Interactions and Translation into Submicromolar Inhibitors. 138:12876-12884. 2016
Annulative methods enable a total synthesis of the complex meroterpene berkeleyone A. 138:14868-14871. 2016
Arylfluorosulfates inactivate intracellular lipid binding protein(s) through chemoselective SuFEx reaction with a binding site Tyr residue. 138:7353-7364. 2016
Asymmetric total syntheses of aspidodasycarpine, lonicerine, and the proposed structure of lanciferine. 138:3982-3985. 2016
Biosynthetic origin of the ether ring in platensimycin. 138:16711-16721. 2016
Branch-selective hydroarylation: iodoarene-olefin cross-coupling. 138:12779-12782. 2016
Capturing unknown substrates via in situ formation of tightly bound bisubstrate adducts: S-adenosyl-vinthionine as a functional probe for AdoMet-dependent methyltransferases. 138:2877-2880. 2016
Catalysis of heterocyclic azadiene cycloaddition reactions by solvent hydrogen bonding: concise total synthesis of methoxatin. 138:12408-12413. 2016
Catalytic enantioselective dihalogenation and the selective synthesis of (-)-deschloromytilipin A and (-)-danicalipin A. 138:5150-5158. 2016
Catalytic, regioselective hydrocarbofunctionalization of unactivated alkenes with diverse C-H nucleophiles. 138:14705-14712. 2016
Cationic polymerization of vinyl ethers controlled by visible light. 138:15535-15538. 2016
Cavitands as chaperones for monofunctional and ring-forming reactions in water. 138:7512-7515. 2016
Cellular protection of SNAP-25 against botulinum neurotoxin/A: inhibition of thioredoxin reductase through a suicide substrate mechanism. 138:5568-5575. 2016
Chemical proteomic profiling of human methyltransferases. 138:13335-13343. 2016
Chemical synthesis and self-assembly of a ladderane phospholipid. 138:15845-15848. 2016
Chemical tools to monitor and manipulate adaptive immune responses. 138:6076-6094. 2016
Cucurbit 7 uril-tetramethylrhodamine conjugate for direct sensing and cellular imaging. 138:16549-16552. 2016
Directed, regiocontrolled hydroamination of unactivated alkenes via protodepalladation. 138:5805-5808. 2016
Discovery of enzymatic targets of transcriptional activators via in vivo covalent chemical capture. 138:12629-12635. 2016
Discovery of pyrophosphate diesters as tunable, soluble, and bioorthogonal linkers for site-specific antibody-drug conjugates. 138:1430-1445. 2016
Diverted total synthesis of promysalin analogs demonstrates that an iron-binding motif is responsible for its narrow-spectrum antibacterial activity. 138:5833-5836. 2016
Evolutionary gain of alanine mischarging to noncognate tRNAs with a G4:U69 base pair. 138:12948-12955. 2016
Extended-charge-transfer excitons in crystalline supramolecular photocatalytic scaffolds. 138:11762-11774. 2016
Finding our way in the dark proteome. 138:9730-9742. 2016
HtrA1 proteolysis of ApoE in vitro is allele selective. 138:9473-9478. 2016
Hydrogen-bonded homoleptic fluoride-diarylurea complexes: structure, reactivity, and coordinating power. 138:13314-13325. 2016
Identification of mechanism-based inactivation in P450-catalyzed cyclopropanation facilitates engineering of improved enzymes. 138:12527-12533. 2016
In situ catalyst modification in atom transfer radical reactions with ruthenium benzylidene complexes. 138:7171-7177. 2016
Iron(II)-catalyzed intermolecular aminofluorination of unfunctionalized olefins using fluoride ion. 138:11360-11367. 2016
Kinetic resolution of benzylamines via palladium(II)-catalyzed C-H cross-coupling. 138:7796-7800. 2016
Ligand promoted meta-C-H chlorination of anilines and phenols. 138:14876-14879. 2016
Ligand-enabled γ-C(sp(3))-H olefination of amines: en route to pyrrolidines. 138:2055-2059. 2016
Ligand-promoted meta-C-H amination and alkynylation. 138:14092-14099. 2016
Ligand-promoted meta-C-H arylation of anilines, phenols, and heterocycles. 138:9269-9276. 2016
Macrocyclization of folded diamines in cavitands. 138:10846-10848. 2016
Metabolically labile fumarate esters impart kinetic selectivity to irreversible inhibitors. 138:15841-15844. 2016
Methionine ligand interaction in a blue copper protein characterized by site-selective infrared spectroscopy. 138:7187-7193. 2016
Oxidative entry into the illicium sesquiterpenes: enantiospecific synthesis of (+)-pseudoanisatin. 138:16616-16619. 2016
Palladium(II)-catalyzed regioselective syn-hydroarylation of disubstituted alkynes using a removable directing group. 138:13076-13081. 2016
Pd-catalyzed α-selective C-H functionalization of olefins: en route to 4-Imino-β-lactams. 138:2146-2149. 2016
Pd-catalyzed γ-C(sp(3))-H arylation of free amines using a transient directing group. 138:14554-14557. 2016
Ph(i-PrO)SiH2: An exceptional reductant for metal-catalyzed hydrogen atom transfers. 138:4962-4971. 2016
Practical Ni-catalyzed aryl-alkyl cross-coupling of secondary redox-active esters. 138:2174-2177. 2016
Radicals: reactive intermediates with translational potential. 138:12692-12714. 2016
Redox-active esters in Fe-catalyzed C-C coupling. 138:11132-11135. 2016
Replacement of 2 '-deoxycytidine by 2 '-deoxycytidine analogues in the E. coli genome. 138:14230-14233. 2016
Replacement of Thymidine by a Modified Base in the Escherichia coli Genome. 138:7272-7275. 2016
Resolution of site-specific conformational heterogeneity in proline-rich molecular recognition by Src homology 3 domains. 138:1130-1133. 2016
Silent encoding of chemical post-translational modifications in phage-displayed libraries. 138:32-35. 2016
Single hydrogen bond donation from flavin N-5 to proximal asparagine ensures FAD reduction in DNA photolyase. 138:4368-4376. 2016
Site-selective aliphatic C-H chlorination using N-chloroamides enables a synthesis of chlorolissoclimide. 138:696-702. 2016
Steric and dynamic parameters influencing in situ cycloadditions to form triazole inhibitors with crystalline acetylcholinesterase. 138:1611-1621. 2016
Streamlined total synthesis of uncialamycin and its application to the synthesis of designed analogues for biological investigations. 138:8235-8246. 2016
Structural analysis of human Argonaute-2 bound to a modified siRNA guide. 138:8694-8697. 2016
Structure of the ent-copalyl diphosphate synthase PtmT2 from streptomyces platensis CB00739, a bacterial type II diterpene synthase. 138:10905-10915. 2016
Structure-guided control of siRNA off-target effects. 138:8667-8669. 2016
Synthesis and biological investigation of Δ12-prostaglandin J3 (Δ12-PGJ3) analogues and related compounds. 138:6550-6560. 2016
Synthesis of (+)-7,20-diisocyanoadociane and liver -stage antiplasmodial activity of the isocyanoterpene class. 138:7268-7271. 2016
Synthesis of a potent vinblastine: rationally designed added benign complexity. 138:8376-8379. 2016
The dependence of carbohydrate-aromatic interaction strengths on the structure of the carbohydrate. 138:7636-7648. 2016
Tilted magnetic levitation enables measurement of the complete range of densities of materials with low magnetic permeability. 138:1252-1257. 2016
Total syntheses of aflavazole and 14-hydroxyaflavinine. 138:15555-15558. 2016
Trapping of the enoyl-acyl carrier protein reductase-acyl carrier protein interaction. 138:3962-3965. 2016
Z-Selective cross-metathesis and homodimerization of 3E-1,3-dienes: reaction optimization, computational analysis, and synthetic applications. 138:14039-14046. 2016
β,γ-vicinal dicarbofunctionalization of alkenyl carbonyl compounds via directed nucleopalladation. 138:15122-15125. 2016
A fluorinated ligand enables room-temperature and regioselective Pd-catalyzed fluorination of aryl triflates and bromides. 137:13433-13438. 2015
A general approach to sequence-controlled polymers using macrocyclic ring opening metathesis polymerization. 137:8038-8041. 2015
A synthesis of alsmaphorazine B demonstrates the chemical feasibility of a new biogenetic hypothesis. 137:7306-7309. 2015
Biochemical establishment and characterization of EncM's Flavin-N5-oxide cofactor. 137:8078-8085. 2015
CalFluors: A universal motif for fluorogenic azide probes across the visible spectrum. 137:7145-7151. 2015
Catalytic chemo-, regio-, and enantioselective bromochlorination of allylic alcohols. 137:3795-3798. 2015
Computational and experimental investigations of the formal dyotropic rearrangements of Himbert arene/allene cycloadducts. 137:6956-6964. 2015
Controlling the architecture, coordination, and reactivity of nanoparticle coating utilizing an amino acid central scaffold. 137:16084-16097. 2015
Cooperative loading and release behavior of a metal-organic receptor. 137:1770-1773. 2015
Drug-triggered and cross-linked self-assembling nanofibrous hydrogels. 137:4823-4830. 2015
Epoxide hydrolase-lasalocid a structure provides mechanistic insight into polyether natural product biosynthesis. 137:86-89. 2015
Genetically encoded fragment-based discovery of glycopeptide ligands for carbohydrate-binding proteins. 137:5248-5251. 2015
Highly selective synthesis of halomon, plocamenone, and isoplocamenone. 137:12784-12787. 2015
Iridium-catalyzed enantioselective allylic substitution of enol silanes from vinylogous esters and amides. 137:13972-13979. 2015
Modular synthetic platform for the construction of functional single-chain polymeric nanoparticles: from aqueous catalysis to photosensitization. 137:13096-13105. 2015
Palladium-catalyzed α,β-dehydrogenation of esters and nitriles. 137:5875-5878. 2015
Parahydrogen-induced polarization by pairwise replacement catalysis on Pt and Ir nanoparticles. 137:1938-1946. 2015
Peptide ligation and RNA cleavage via an abiotic template interface.. 137:3751-3754. 2015
Sequence-specific, nanomolar peptide binding via cucurbit[8]uril-induced folding and inclusion of neighboring side chains. 137:3663-3669. 2015
Specific inhibition of microRNA processing using L-RNA aptamers. 137:16032-16037. 2015
Structural elucidation and synthesis of eudistidine A: an unusual polycyclic marine alkaloid that blocks interaction of the protein binding domains of p300 and HIF-1α. 137:5569-5575. 2015
Structure and substrate sequestration in the pyoluteorin type II peptidyl carrier protein PltL. 137:11546-11549. 2015
Supramolecular packing controls H-2 photocatalysis in chromophore amphiphile hydrogels. 137:15241-15246. 2015
Synthesis and potent antimalarial activity of kalihinol B. 137:4912-4915. 2015
Synthetic polymer hybridization with DNA and RNA directs nanoparticle loading, silencing delivery, and aptamer function. 137:8920-8923. 2015
Systematic evaluation of bioorthogonal reactions in live cells with clickable Halo Tag ligands: implications for intracellular imaging. 137:11461-11475. 2015
Total synthesis and biological investigation of (-)-promysalin. 137:7314-7317. 2015
Total synthesis of Epoxyeujindole A. 137:13764-13767. 2015
Total synthesis of hyperforin. 137:10516-10519. 2015
A deep cavitand templates lactam formation in water. 137:14582-14585. 2015
A fluorogenic aryl fluorosulfate for intraorganellar transthyretin imaging in living cells and in Caenorhabditis elegans. 137:7404-7414. 2015
A new strategy for smoking cessation: characterization of a bacterial enzyme for the degradation of nicotine. 137:10136-10139. 2015
A reversible and highly selective inhibitor of the proteasomal ubiquitin receptor rpn13 is toxic to multiple myeloma cells. 137:6312-6319. 2015
An anti-B cell maturation antigen bispecific antibody for multiple myeloma. 137:5288-5291. 2015
An immunosuppressive antibody-drug conjugate. 137:3229-3232. 2015
Chemical protein synthesis using a second-generation N-acylurea linker for the preparation of peptide-thioester precursors. 137:7197-7209. 2015
Cofactor-mediated conformational dynamics promote product release from Escherichia coli dihydrofolate reductase via an allosteric pathway. 137:9459-9468. 2015
Development of a concise synthesis of ouabagenin and hydroxylated corticosteroid analogues. 137:1330-1340. 2015
Fluorescence turn-on folding sensor to monitor proteome stress in live cells. 137:11303-11311. 2015
Highly selective, reversible inhibitor identified by comparative chemoproteomics modulates diacylglycerol lipase activity in neurons. 137:8851-8857. 2015
Hydromethylation of unactivated olefins. 137:8046-8049. 2015
Inhibition of non-ATG translational events in cells via covalent small molecules targeting RNA. 137:5336-5345. 2015
Kinetic profiling of catalytic organic reactions as a mechanistic tool. 137:10852-10866. 2015
Ligand-enabled cross-coupling of C(sp(3))-H bonds with arylsilanes. 137:4618-4621. 2015
Ligand-enabled meta-C-H alkylation and arylation using a modified norbornene. 137:11574-11577. 2015
Ligand-enabled stereoselective β-C(sp(3))-H fluorination: Synthesis of unnatural enantiopure anti-β-fluoro-α-amino acids. 137:7067-7070. 2015
Ligand-enabled β-C-H arylation of α-amino acids using a simple and practical auxiliary. 137:3338-3351. 2015
Mechanistic details of Pd(II)-catalyzed C-H iodination with molecular I-2: oxidative addition vs electrophilic cleavage. 137:9022-9031. 2015
Mechanistic rationalization of unusual sigmoidal kinetic profiles in the Machetti-De Sarlo cycloaddition reaction. 137:2386-2391. 2015
Modular degradable hydrogels based on thiol-reactive oxanorbornadiene linkers. 137:4984-4987. 2015
Mono-oxidation of bidentate bis-phosphines in catalyst activation: kinetic and mechanistic studies of a Pd/xantphos-catalyzed C-H functionalization. 137:13272-13281. 2015
Monoselective o-C-H functionalizations of mandelic acid and α-phenylglycine. 137:9877-9884. 2015
Origins of initiation rate differences in ruthenium olefin metathesis catalysts containing chelating benzylidenes. 137:5782-5792. 2015
Palladium(II)-catalyzed highly enantioselective C-H arylation of cyclopropylmethylamines. 137:2042-2046. 2015
Pd(II)-catalyzed C-H functionalizations directed by distal weakly coordinating functional groups. 137:4391-4397. 2015
Photoligation of an amphiphilic polymer with mixed coordination provides compact and reactive quantum dots. 137:5438-5451. 2015
Practical Pd(II)-catalyzed C-H alkylation with epoxides: one-step syntheses of 3,4-dihydroisocoumarins. 137:10950-10953. 2015
Rational design of antibody protease inhibitors. 137:4042-4045. 2015
Rational ligand design for the arylation of hindered primary amines guided by reaction progress kinetic analysis. 137:3085-3092. 2015
Redirection of genetically engineered CAR-T cells using bifunctional small molecules. 137:2832-2835. 2015
Scalable C-H oxidation with copper: synthesis of polyoxypregnanes. 137:13776-13779. 2015
Synthesis and biological evaluation of dimeric furanoid macroheterocycles: discovery of new anticancer agents. 137:4766-4770. 2015
Total syntheses and initial evaluation of [?[C(-S)NH]Tpg(4)]vancomycin, [?[C(-NH)NH]Tpg(4)]vancomycin, [?[CH2NH]Tpg(4)]vancomycin, and their (4-Chlorobiphenyl)methyl derivatives: synergistic binding pocket and peripheral modifications for the glycopeptide antibiotics. 137:3693-3704. 2015
Total synthesis of verruculogen and fumitremorgin a enabled by ligand-controlled C-H borylation. 137:10160-10163. 2015
UV and sunlight driven photoligation of quantum dots: understanding the photochemical transformation of the ligands. 137:2704-2714. 2015
α-Arylation of saturated azacycles and N-methylamines via palladium(II)-catalyzed C(sp(3))-H coupling. 137:11876-11879. 2015
γ,δ,ε-C(sp(3))-H functionalization through directed radical H-abstraction. 137:5871-5874. 2015
A near-IR uncaging strategy based on cyanine photochemistry. 136:14153-14159. 2014
A potent α/β-peptide analogue of GLP-1 with prolonged action in vivo. 136:12848-12851. 2014
Asymmetric Mannich synthesis of α-amino esters by anion-binding catalysis. 136:12872-12875. 2014
Bifacial peptide nucleic acid as an allosteric switch for aptamer and ribozyme function. 136:7265-7268. 2014
Characterization of native protein complexes using ultraviolet photodissociation mass spectrometry. 136:12920-12928. 2014
Concerted versus stepwise mechanism in thymidylate synthase. 136:9850-9853. 2014
Criteria for selecting PEGylation sites on proteins for higher thermodynamic and proteolytic stability. 136:17547-17560. 2014
Data-driven synthesis of proteolysis-resistant peptide hormones. 136:17710-17713. 2014
Diastereo- and enantioselective iridium-catalyzed allylation of cyclic ketone enolates: synergetic effect of ligands and barium enolates. 136:15825-15828. 2014
Enhancing the specificity of recombinase-mediated genome engineering through dimer interface redesign. 136:5047-5056. 2014
Epitope discovery for a synthetic polymer nanoparticle: a new strategy for developing a peptide tag. 136:1194-1197. 2014
Formal carbene insertion into C-C bond: Rh(I)-catalyzed reaction of benzocyclobutenols with diazoesters. 136:3013-3015. 2014
Four-step synthesis of the antimalarial cardamom peroxide via an oxygen stitching strategy. 136:5287-5290. 2014
Glycocalyx remodeling with proteoglycan mimetics promotes neural specification in embryonic stem cells. 136:10565-10568. 2014
Intramolecular [3 + 2] cyclocondensations of alkenes with indolidenes and indolidenium cations. 136:15138-15141. 2014
Iridium-catalyzed enantioselective allyl-alkene coupling. 136:3006-3009. 2014
Iron(II)-catalyzed intermolecular amino-oxygenation of olefins through the N-O bond cleavage of functionalized hydroxylamines. 136:13186-13189. 2014
Long-range ordering of highly charged self-assembled nanofilaments. 136:14377-14380. 2014
Modeling linear and cyclic PKS intermediates through atom replacement. 136:16792-16799. 2014
Monitoring native p38α:MK2/3 complexes via trans delivery of an ATP acyl phosphate probe. 136:4664-4669. 2014
Multifunctional π-expanded macrocyclic oligothiophene 6-mers and related macrocyclic oligomers. 136:2389-2396. 2014
Palladium-catalyzed intramolecular asymmetric C-H functionalization/cyclization reaction of metallocenes: an efficient approach toward the synthesis of planar chiral metallocene compounds. 136:4472-4475. 2014
Rapid, hydrolytically stable modification of aldehyde-terminated proteins and phage libraries. 136:8149-8152. 2014
Rational design of a non-canonical "sticky-ended" collagen triple helix. 136:7535-7538. 2014
Rectification in tunneling junctions: 2,2'-bipyridyl-terminated n-alkanethiolates. 136:17155-17162. 2014
Self-assembly of fiber-forming collagen mimetic peptides controlled by triple-helical nucleation. 136:14417-14424. 2014
Stereodivergent α-allylation of linear aldehydes with dual iridium and amine catalysis. 136:3020-3023. 2014
Synthesis of angularly substituted trans-fused hydroindanes by convergent coupling of acyclic precursors. 136:8209-8212. 2014
Tapping a bacterial enzymatic pathway for the preparation and manipulation of synthetic nanomaterials. 136:17378-17381. 2014
Total synthesis of halichondrin A, the missing member in the halichondrin class of natural products. 136:5171-5176. 2014
Total synthesis of rubriflordilactone A. 136:16477-16480. 2014
Total synthesis of taiwaniadducts B, C, and D. 136:8185-8188. 2014
A genetically encoded aza-Michael acceptor for covalent cross-linking of protein-receptor complexes. 136:8411-8417. 2014
A mechanistic change results in 100 times faster CH functionalization for ethane versus methane by a homogeneous Pt catalyst. 136:10085-10094. 2014
A mild, ferrocene-catalyzed C-H imidation of (hetero)arenes. 136:5279-5282. 2014
A practical and catalytic reductive olefin coupling. 136:1304-1307. 2014
A strategy for complex dimer formation when biomimicry fails: total synthesis of ten coccinellid alkaloids. 136:9743-9753. 2014
A unified approach to ent-atisane diterpenes and related alkaloids: synthesis of (-)-methyl atisenoate, (-)-isoatisine, and the hetidine skeleton. 136:12592-12595. 2014
Alkyl groups fold to fit within a water-soluble cavitand. 136:5264-5266. 2014
Axinellamines as broad-spectrum antibacterial agents: scalable synthesis and biology. 136:15403-15413. 2014
C-H methylation of heteroarenes inspired by radical SAM methyl transferase. 136:4853-4856. 2014
Cu(II)-mediated C-H amidation and amination of arenes: exceptional compatibility with heterocycles. 136:3354-3357. 2014
Cu(II)-mediated ortho C-H alkynylation of (hetero)arenes with terminal alkynes. 136:11590-11593. 2014
De novo-designed enzymes as small-molecule-regulated fluorescence imaging tags and fluorescent reporters. 136:13102-13105. 2014
Determinants of regioselective hydroxylation in the fungal polysaccharide monooxygenases. 136:562-565. 2014
Development of a concise synthesis of (+)-ingenol. 136:5799-5810. 2014
Evidence of an unusual N-H…N hydrogen bond in proteins. 136:13474-13477. 2014
Ligand-enabled gamma-C-H olefination and carbonylation: construction of beta-quaternary carbon centers. 136:5267-5270. 2014
Ligand-promoted alkylation of C(sp(3))-H and C(sp(2))-H bonds. 136:13194-13197. 2014
Mapping the protein interaction landscape for fully functionalized small-molecule probes in human cells. 136:10777-10782. 2014
Molecular rotors as conditionally fluorescent labels for rapid detection of biomolecular interactions. 136:6159-6162. 2014
Natural-like replication of an unnatural base pair for the expansion of the genetic alphabet and biotechnology applications. 136:826-829. 2014
Palau'chlor: a practical and reactive chlorinating reagent. 136:6908-6911. 2014
Palladium(II)-catalyzed enantioselective C(sp(3))-H activation using a chiral hydroxamic acid ligand. 136:8138-8142. 2014
Palladium-catalyzed meta-selective C-H bond activation with a nitrile-containing template: computational study on mechanism and origins of selectivity. 136:344-355. 2014
Pd(II)-catalyzed meta-C-H olefination, arylation, and acetoxylation of indolines using a U-shaped template. 136:10807-10813. 2014
Quantitative analysis of rRNA modifications using stable isotope labeling and mass spectrometry. 136:2058-2069. 2014
Rational design of CXCR4 specific antibodies with elongated CDRs. 136:10557-10560. 2014
Remodeling natural products: chemistry and serine hydrolase activity of a rocaglate-derived beta-lactone. 136:2659-2664. 2014
Role of N-acyl amino acid ligands in Pd(II)-catalyzed remote C-H activation of tethered arenes. 136:894-897. 2014
Selective electrocatalytic oxidation of a re-methyl complex to methanol by a surface-bound Ru(II) polypyridyl catalyst. 136:15845-15848. 2014
Selective monooxidation of light alkanes using chloride and iodate. 136:8393-8401. 2014
Simple, chemoselective hydrogenation with thermodynamic stereocontrol. 136:1300-1303. 2014
Simple, chemoselective, catalytic olefin isomerization. 136:16788-16791. 2014
Site-selective C(sp3)-H functionalization of di-, tri-, and tetrapeptides at the N-terminus. 136:16940-16946. 2014
Spontaneous prebiotic formation of a beta-ribofuranoside that self-assembles with a complementary heterocycle. 136:5640-5646. 2014
Stereoselective 1,3-insertions of rhodium(II) azavinyl carbenes. 136:195-202. 2014
Synthesis and biological evaluation of QRSTUVWXYZA' domains of maitotoxin. 136:16444-16451. 2014
Tet-mediated formation of 5-hydroxymethylcytosine in RNA. 136:11582-11585. 2014
Total syntheses of (-)-kopsifoline D and (-)-deoxoapodine: divergent total synthesis via late-stage key strategic bond formation. 136:3312-3317. 2014
Total syntheses of (-)-pyrimidoblamic acid and P-3A. 136:2119-2125. 2014
Total synthesis of Psi C(=NH)NH Tpg(4) vancomycin and its ((4)-chlorobiphenyl)methyl derivative: impact of peripheral modifications on vancomycin analogues redesigned for dual D-Ala-D-Ala and D-Ala-D-Lac binding. 136:13522-13525. 2014
Total synthesis of dixiamycin B by electrochemical oxidation. 136:5571-5574. 2014
Total synthesis of viridicatumtoxin B and analogues thereof: strategy evolution, structural revision, and biological evaluation. 136:12137-12160. 2014
Two-phase synthesis of (-)-taxuyunnanine D. 136:4909-4912. 2014
2-Bromopalmitate analogues as activity-based probes to explore palmitoyl acyltransferases. 135:7082-7085. 2013
Catalytic enantioselective dibromination of allylic alcohols. 135:12960-12963. 2013
Chemoproteomic discovery of cysteine-containing human short open reading frames. 135:16750-16753. 2013
Combinatorial generation of complexity by redox enzymes in the chaetoglobosin A biosynthesis. 135:7371-7377. 2013
Complete protein characterization using top-down mass spectrometry and ultraviolet photodissociation. 135:12646-12651. 2013
Computation and experiment reveal that the ring-rearrangement metathesis of Himbert cycloadducts can be subject to kinetic or thermodynamic control. 135:17585-17594. 2013
Computational design of an unnatural amino acid dependent metalloprotein with atomic level accuracy. 135:13393-13399. 2013
Cyclopentannulation of conjugated enones using a vinyldiazomethane-based reagent. 135:12188-12191. 2013
Enantioselective redox-relay oxidative Heck arylations of acyclic alkenyl alcohols using boronic acids. 135:6830-6833. 2013
Engineering hydrophobic protein-carbohydrate interactions to fine-tune monoclonal antibodies. 135:9723-9732. 2013
Hydroxyproline-free single composition ABC collagen heterotrimer. 135:6014-6017. 2013
Iridium-catalyzed enantioselective allylic vinylation. 135:994-997. 2013
Iron(II)-catalyzed intramolecular aminohydroxylation of olefins with functionalized hydroxylamines. 135:3343-3346. 2013
Metabolic perturbation of an essential pathway: evaluation of a glycine precursor of coenzyme A. 135:5962-5965. 2013
Palladium-catalyzed carbene migratory insertion using conjugated ene-yne-ketones as carbene precursors. 135:13502-13511. 2013
Pd-catalyzed chemoselective Catellani ortho-arylation of iodopyrroles: rapid total synthesis of rhazinal. 135:9318-9321. 2013
Productive chemical interaction between a bacterial microcolony couple is enhanced by periodic relocation. 135:2242-2247. 2013
Protein-like tertiary folding behavior from heterogeneous backbones. 135:12528-12531. 2013
Residue-dependent adsorption of model oligopeptides on gold. 135:15040-15052. 2013
Rhodium-catalyzed conversion of furans to highly functionalized pyrroles. 135:4716-4718. 2013
Room temperature phosphorescence of metal-free organic materials in amorphous polymer matrices. 135:6325-6329. 2013
Studies on the Himbert intramolecular arene/allene Diels-Alder cycloaddition. Mechanistic studies and expansion of scope to all-carbon tethers. 135:7339-7348. 2013
Sulfonyl 3-alkynyl pantetheinamides as mechanism-based cross-linkers of acyl carrier protein dehydratase. 135:8846-8849. 2013
Targeted disruption of transcriptional regulators in Chaetomium globosum activates biosynthetic pathways and reveals transcriptional regulator-like behavior of aureonitol. 135:13446-13455. 2013
The designability of protein switches by chemical rescue of structure: mechanisms of inactivation and reactivation. 135:18840-18849. 2013
Ultrafast structural dynamics inside planar phospholipid multibilayer model cell membranes measured with 2D IR spectroscopy. 135:11063-11074. 2013
A GTP affinity probe for proteomics highlights flexibility in purine nucleotide selectivity. 135:4676-4679. 2013
A Pd(0)-mediated indole (macro)cyclization reaction. 135:1600-1606. 2013
A dynamic structural model of expanded RNA CAG repeats: A refined X-ray structure and computational investigations using molecular dynamics and umbrella sampling simulations. 135:3528-3538. 2013
A genetically encoded fluorescent probe in mammalian cells. 135:12540-12543. 2013
Amplified halogen bonding in a small space. 135:13672-13675. 2013
Aromatic sulfonyl fluorides covalently kinetically stabilize transthyretin to prevent amyloidogenesis while affording a fluorescent conjugate. 135:5656-5668. 2013
Binding of a structured D-RNA molecule by an L-RNA aptamer. 135:13290-13293. 2013
Bioconjugation by native chemical tagging of C-H bonds. 135:12994-12997. 2013
Broadly applicable methodology for the rapid and dosable small molecule-mediated regulation of transcription factors in human cells. 135:8129-8132. 2013
Catalytic hydrotrifluoromethylation of unactivated alkenes. 135:2505-2508. 2013
Cross-coupling of remote meta-C-H bonds directed by a U-shaped template. 135:18056-18059. 2013
Development of a high-throughput screen and its use in the discovery of Streptococcus pneumoniae immunoglobulin A1 protease inhibitors. 135:10014-10017. 2013
Diced electrophoresis gel assay for screening enzymes with specified activities. 135:6002-6005. 2013
Dynamics of site switching in DNA polymerase. 135:4735-4742. 2013
Enantio- and diastereoselective synthesis of N-acetyl dihydrotetrafibricin methyl ester. 135:5340-5343. 2013
Enantioselective synthesis of (Z)- and (E)-2-methyl-1,5-anti-pentenediols via an allene hydroboration-double-allylboration reaction sequence. 135:9512-9517. 2013
Expanding the scope of replicable unnatural DNA: Stepwise optimization of a predominantly hydrophobic base pair 2013
Hydrogen-bonded capsules in water. 135:18064-18066. 2013
Ligand-accelerated ortho-C-H alkylation of arylcarboxylic acids using alkyl boron reagents. 135:17508-17513. 2013
Mechanistic insights into the LsrK kinase required for autoinducer-2 quorum sensing activation. 135:7827-7830. 2013
Mimicry of high-density lipoprotein: functional peptide-lipid nanoparticles based on multivalent peptide constructs. 135:13414-13424. 2013
Modulating cocaine vaccine potency through hapten fluorination. 135:2971-2974. 2013
Mutational analysis of 48G7 reveals that somatic hypermutation affects both antibody stability and binding affinity. 135:9980-9983. 2013
Palladium(0)-catalyzed alkynylation of C(sp3)-H bonds. 135:3387-3390. 2013
Pd(II)-catalyzed C-H iodination using molecular I2 as the sole oxidant. 135:10326-10329. 2013
Pd(II)-catalyzed enantioselective C-H activation/C-O bond formation: synthesis of chiral benzofuranones. 135:1236-1239. 2013
Pd(II)-catalyzed ortho- or meta-C-H olefination of phenol derivatives. 135:7567-7571. 2013
Pd(II)-catalyzed phosphorylation of aryl C-H bonds. 135:9322-9325. 2013
Pd-catalyzed enantioselective C-H iodination: asymmetric synthesis of chiral diarylmethylamines. 135:16344-16347. 2013
Post-polyketide synthase steps in iso-migrastatin biosynthesis, featuring tailoring enzymes with broad substrate specificity. 135:2489-2492. 2013
Production of tartrates by cyanide-mediated dimerization of glyoxylate: a potential abiotic pathway to the citric acid cycle. 135:13440-13445. 2013
Radical-based regioselective C-H functionalization of electron-deficient heteroarenes: scope, tunability, and predictability. 135:12122-12134. 2013
Rational design of fatty acid amide hydrolase inhibitors that act by covalently bonding to two active site residues. 135:6289-6299. 2013
Selective detection and inhibition of active caspase-3 in cells with optimized peptides. 135:12869-12876. 2013
Self-assembled antibody multimers through peptide nucleic acid conjugation. 135:340-346. 2013
Sequential C-H functionalization reactions for the enantioselective synthesis of highly functionalized 2,3-dihydrobenzofurans. 135:6774-6777. 2013
Site-specific antibody-polymer conjugates for siRNA delivery. 135:13885-13891. 2013
Small-molecule inducer of β cell proliferation identified by high-throughput screening. 135:1669-1672. 2013
Stilbene vinyl sulfonamides as fluorogenic sensors of and traceless covalent kinetic stabilizers of transthyretin that prevent amyloidogenesis. 135:17869-17880. 2013
Structural and energetic basis of carbohydrate-aromatic packing interactions in proteins. 135:9877-9884. 2013
Structural and thermodynamic basis of (+)-α-pinene binding to human cytochrome P450 2B6. 135:10433-10440. 2013
Structural insights into DNA replication without hydrogen bonds. 135:18637-18643. 2013
Structure and flexibility of nanoscale protein cages designed by symmetric self-assembly. 135:7738-7743. 2013
Synthesis of (-)-neothiobinupharidine. 135:1209-1212. 2013
Synthesis of biologically active N- and O-linked glycans with multisialylated poly-N-acetyllactosamine extensions using P. damsela α2-6 sialyltransferase. 135:18280-18283. 2013
The revolution and evolution of shotgun proteomics for large-scale proteome analysis. 135:1629-1640. 2013
Toward the molecular mechanism(s) by which EGCG treatment remodels mature amyloid fibrils. 135:7503-7510. 2013
Transannulation of 1-sulfonyl-1,2,3-triazoles with heterocumulenes. 135:4652-4655. 2013
Understanding the reactivity of Pd(0)/PR3-catalyzed intermolecular C(sp(3))-H bond arylation. 135:14206-14214. 2013
Using reduced catalysts for oxidation reactions: mechanistic studies of the "Periana-Catalytica" system for CH4 oxidation. 135:14644-14658. 2013
"Donor-two-acceptor" dye design: a distinct gateway to NIR fluorescence. 134:20412-20420. 2012
A tetradentate ligand for the enantioselective Ti(IV)-promoted oxidation of sulfides to sulfoxides: origin of enantioselectivity. 134:17354-17357. 2012
An endoglycosidase with alternative glycan specificity allows broadened glycoprotein remodelling. 134:8030-8033. 2012
Antibody-free reading of the histone code using a simple chemical sensor array. 134:11674-11680. 2012
Azurin as a protein scaffold for a low-coordinate nonheme iron site with a small-molecule binding pocket. 134:19746-19757. 2012
C-C bond formation via copper-catalyzed conjugate addition reactions to enones in water at room temperature.. 134:19985-19988. 2012
Computational design of an α-gliadin peptidase. 134:20513-20520. 2012
Conformational dynamics and stability of HP35 studied with 2D IR vibrational echoes. 134:12118-12124. 2012
Contact de-electrification of electrostatically charged polymers. 134:20151-20159. 2012
Dehydratase-specific probes for fatty acid and polyketide synthases. 134:769-772. 2012
Design strategies for the sequence-based mimicry of side-chain display in protein β-sheets by α/β-peptides. 134:15906-15913. 2012
Designing allosteric control into enzymes by chemical rescue of structure. 134:10055-10060. 2012
Direct arylation/alkylation/magnesiation of benzyl alcohols in the presence of Grignard reagents via Ni-, Fe-, or Co-catalyzed sp3 C-O bond activation. 134:14638-14641. 2012
Discrete assembly of synthetic peptide-DNA triplex structures from polyvalent melamine-thymine bifacial recognition. 134:832-835. 2012
Enhancement of α-helix mimicry by an α/β-peptide foldamer via incorporation of a dense ionic side-chain array. 134:7317-7320. 2012
Evaluation of diverse α/β-backbone patterns for functional α-helix mimicry: analogues of the Bim BH3 domain. 134:315-323. 2012
Generation of thiocillin ring size variants by prepeptide gene replacement and in vivo processing by Bacillus cereus. 134:10313-10316. 2012
Improved ruthenium catalysts for Z-selective olefin metathesis. 134:693-699. 2012
Investigating the dearomative rearrangement of biaryl phosphine-ligated Pd(II) complexes. 134:19922-19934. 2012
Iridium-catalyzed enantioselective polyene cyclization. 134:20276-20278. 2012
Macromolecular crowding and protein stability. 134:16614-16618. 2012
Molecular encapsulation in pyrogallolarene hexamers under nonequilibrium conditions. 134:15000-15009. 2012
Photoinduced phase transfer of luminescent quantum dots to polar and aqueous media.. 134:16370-16378. 2012
Photoreductive uncaging of fluorophore in response to protein oligomers by templated reaction in vitro and in cellulo. 134:20013-20016. 2012
Rational design of single-composition ABC collagen heterotrimers. 134:1430-1433. 2012
Self-assembly of highly ordered peptide amphiphile metalloporphyrin arrays. 134:14646-14649. 2012
Stereoselective synthesis of S-linked α(2→8) and α(2→8)/α(2→9) hexasialic acids. 134:16074-16079. 2012
Total synthesis of (-)-fusarisetin A and reassignment of the absolute configuration of its natural counterpart. 134:920-923. 2012
A chemical approach for cell-specific targeting of nanomaterials: Small-molecule-initiated misfolding of nanoparticle corona proteins. 134:4100-4103. 2012
A designer bleomycin with significantly improved DNA cleavage activity. 134:13501-13509. 2012
A new reagent for direct difluoromethylation. 134:1494-1497. 2012
A stereoselective hydroamination transform to access polysubstituted indolizidines. 134:2012-2015. 2012
Acyl and silyl group effects in reactivity-based one-pot glycosylation: Synthesis of embryonic stem cell surface carbohydrates lc(4) and iv(2)fuc-lc(4). 134:4549-4552. 2012
Alkane lengths determine encapsulation rates and equilibria. 134:8070-8073. 2012
Alpha-glycosylation by d-glucosamine-derived donors: Synthesis of heparosan and heparin analogues that interact with mycobacterial heparin-binding hemagglutinin. 134:8988-8995. 2012
Arylation of rhodium(II) azavinyl carbenes with boronic acids. 134:14670-14673. 2012
Asymmetric synthesis of dihydroindanes by convergent alkoxide-directed metallacycle-mediated bond formation. 134:2766-2774. 2012
C4-alkoxy-hpd: A potent class of synthetic modulators surpassing nature in al-2 quorum sensing. 134:13562-13564. 2012
Chemical and structural analysis of an antibody folding intermediate trapped during glycan biosynthesis. 134:17554-17563. 2012
Competitive activity-based protein profiling identifies aza-β-lactams as a versatile chemotype for serine hydrolase inhibition. 134:5068-5071. 2012
Concise synthetic approaches for the Laurencia family: formal total syntheses of (±)-laurefucin and (±)-E- and (±)-Z-pinnatifidenyne. 134:17714-17721. 2012
Confirming target engagement for reversible inhibitors in vivo by kinetically tuned activity-based probes. 134:10345-10348. 2012
Conformations and fluorescence of encapsulated stilbene. 134:4346-4354. 2012
Curtin-Hammett paradigm for stereocontrol in organocatalysis by diarylprolinol ether catalysts. 134:6741-6750. 2012
Degradable conjugates from oxanorbornadiene reagents. 134:6491-6497. 2012
Design of a bioactive small molecule that targets the myotonic dystrophy type 1 RNA via an RNA motif-ligand database and chemical similarity searching. 134:4731-4742. 2012
Enantioselective synthesis of anti- and syn-homopropargyl alcohols via chiral Brønsted acid catalyzed asymmetric allenylboration reactions. 134:10947-10952. 2012
Encapsulation of ion pairs in extended, self-assembled structures. 134:11971-11973. 2012
Exploratory experiments on the chemistry of the "glyoxylate scenario": Formation of ketosugars from dihydroxyfumarate. 134:3577-3589. 2012
Fe(III)/NaBH4-mediated free radical hydrofluorination of unactivated alkenes. 134:13588-13591. 2012
Fully functionalized small-molecule probes for integrated phenotypic screening and target identification. 134:10385-10388. 2012
Generation of candidate ligands for nicotinic acetylcholine receptors via in situ click chemistry with a soluble acetylcholine binding protein template. 134:6732-6740. 2012
Glycomimetic ligands for the human asialoglycoprotein receptor. 134:1978-1981. 2012
Guest-induced, selective formation of isomeric capsules with imperfect walls. 134:17498-17501. 2012
Highly stereoselective synthesis of anti,anti-dipropionate stereotriads: a solution to the long-standing problem of challenging mismatched double asymmetric crotylboration reactions. 134:3925-3931. 2012
In silica-aided design of a glycan ligand of sialoadhesin for in vivo targeting of macrophages. 134:15696-15699. 2012
Incorporation of disulfide containing protein modules into multivalent antigenic conjugates: Generation of antibodies against the thrombin-sensitive region of murine protein S. 134:19318-19321. 2012
Intermolecular Ritter-type C-H amination of unactivated sp3 carbons. 134:2547-2550. 2012
Key mechanistic features of enantioselective c-h bond activation reactions catalyzed by (chiral mono-n-protected amino acid)-pd(ii) complexes. 134:1690-1698. 2012
Ligand-dependent exponential amplification of a self-replicating L-RNA enzyme. 134:8050-8053. 2012
Ligand-enabled methylene C(sp3)-H bond activation with a Pd(II) catalyst. 134:18570-18572. 2012
Mechanistic rationalization of unusual kinetics in Pd-catalyzed C-H olefination. 134:4600-4606. 2012
New insights into the mechanism and an expanded scope of the Fe(III)-mediated vinblastine coupling reaction. 134:13240-13243. 2012
Oxidative cleavage of cellulose by fungal copper-dependent polysaccharide monooxygenases. 134:890-892. 2012
Pasteur's tweezers revisited: on the mechanism of attrition-enhanced deracemization and resolution of chiral conglomerate solids. 134:12629-12636. 2012
Pd(II)-catalyzed ortho trifluoromethylation of arenes and insights into the coordination mode of acidic amide directing groups. 134:11948-11951. 2012
Pd-catalyzed oxidative ortho-c-h borylation of arenes. 134:134-137. 2012
Quantitative analysis of multisite protein-ligand interactions by NMR: binding of intrinsically disordered p53 transactivation subdomains with the TAZ2 domain of CBP. 134:3792-3803. 2012
Quantum dots as simultaneous acceptors and donors in time-gated Förster resonance energy transfer relays: characterization and biosensing. 134:1876-1891. 2012
Rhodium(II)-catalyzed asymmetric sulfur(VI) reduction of diazo sulfonylamidines. 134:2477-2480. 2012
Ribosomal route to small-molecule diversity. 134:418-425. 2012
Scalable, divergent synthesis of meroterpenoids via "borono-sclareolide". 134:8432-8435. 2012
Seeing citrulline: Development of a phenylglyoxal-based probe to visualize protein citrullination. 134:17015-17018. 2012
Selective stabilization of self-assembled hydrogen-bonded molecular capsules through pi-pi interactions. 134:2914-2917. 2012
Silver(I)-promoted conversion of thioamides to amidines: divergent synthesis of a key series of vancomycin aglycon residue 4 amidines that clarify binding behavior to model ligands. 134:8790-8793. 2012
Single-molecule Förster resonance energy transfer reveals an innate fidelity checkpoint in DNA polymerase I. 134:11261-11268. 2012
Synthesis and biological evaluation of epidithio-, epitetrathio-, and bis-(methylthio)diketopiperazines: synthetic methodology, enantioselective total synthesis of epicoccin G, 8,8'-epi-ent-rostratin B, gliotoxin, gliotoxin G, emethallicin E, and haematocin and discovery of new antiviral and antimalarial agents. 134:17320-17332. 2012
Synthesis of a potent antimalarial amphilectene. 134:19604-19606. 2012
Synthesis of alkaloid (-)-205b via stereoselective reductive cross-coupling and intramolecular 3+2 cycloaddition. 134:15237-15240. 2012
Synthesis of bispecific antibodies using genetically encoded unnatural amino acids. 134:9918-9921. 2012
The glmS ribozyme cofactor is a general acid-base catalyst. 134:19043-19049. 2012
Three-component coupling sequence for the regiospecific synthesis of substituted pyridines. 134:1352-1356. 2012
Total syntheses of anominine and tubingensin a. 134:8078-8081. 2012
Total synthesis of [Psi[C(═S)NH]Tpg4]vancomycin aglycon, [Psi[C(═NH)NH]Tpg4]vancomycin aglycon, and related key compounds: reengineering vancomycin for dual D-Ala-D-Ala and D-Ala-D-Lac binding. 134:1284-1297. 2012
Trapping of an intermediate in the reaction catalyzed by flavin-dependent thymidylate synthase. 134:4442-4448. 2012
Understanding reactivity and stereoselectivity in palladium-catalyzed diastereoselective sp3 C-H bond activation: intermediate characterization and computational studies. 134:14118-14126. 2012
Broad distribution of energetically important contacts across an extended protein interface. 133:10038-10041. 2011
Combinatorially inducible RNA interference triggered by chemically modified oligonucleotides. 133:2783-2788. 2011
Development of proneurogenic, neuroprotective small molecules. 133:1428-1437. 2011
Discovery of a protein-metabolite interaction between unsaturated fatty acids and the nuclear receptor Nur77 using a metabolomics approach. 133:17168-17171. 2011
Divergent synthesis and chemical reactivity of bicyclic lactone fragments of complex rearranged spongian diterpenes. 133:17494-17503. 2011
Dual catalysis in enantioselective oxidopyrylium-based [5 + 2] cycloadditions. 133:14578-14581. 2011
Enantioselective total synthesis of aplyviolene. 133:16425-16427. 2011
Evidence for in situ catalyst modification during the Pd-catalyzed conversion of aryl triflates to aryl fluorides. 133:18106-18109. 2011
Hairpin folding behavior of mixed α/β-peptides in aqueous solution. 133:4246-4249. 2011
Lyotropic liquid crystals formed from ACHC-rich β-peptides. 133:13604-13613. 2011
Metal-substituted protein MRI contrast agents engineered for enhanced relaxivity and ligand sensitivity. 133:649-651. 2011
Molecular recognition of insulin by a synthetic receptor. 133:8810-8813. 2011
Monoalkylglycerol ether lipids promote adipogenesis. 133:5178-5181. 2011
Nucleic acid-templated energy transfer leading to a photorelease reaction and its application to a system displaying a nonlinear response. 133:18110-18113. 2011
Positive and negative design leads to compositional control in AAB collagen heterotrimers. 133:5432-5443. 2011
Protein dynamics in cytochrome P450 molecular recognition and substrate specificity using 2D IR vibrational echo spectroscopy. 133:3995-4004. 2011
Self-assembly and orientation of hydrogen-bonded oligothiophene polymorphs at liquid-membrane-liquid interfaces. 133:16486-16494. 2011
Synthesis and characterization of a series of highly fluorogenic substrates for glutathione transferases, a general strategy. 133:14109-14119. 2011
Temperature dependent equilibrium native to unfolded protein dynamics and properties observed with IR absorption and 2D IR vibrational echo experiments. 133:6681-6691. 2011
Total synthesis and biological evaluation of pederin, psymberin, and highly potent analogs. 133:16668-16679. 2011
Total synthesis of the Bacteroides fragilis zwitterionic polysaccharide A1 repeating unit. 133:102-107. 2011
Unraveling the mechanism of cascade reactions of zincke aldehydes. 133:3895-3905. 2011
A carbohydrate-conjugated deep cavitand permits observation of caviplexes in human serum. 133:19653-19655. 2011
A concise, stereocontrolled total synthesis of rippertenol. 133:8850-8853. 2011
A general strategy for the stereocontrolled preparation of diverse 8- and 9-membered Laurencia-type bromoethers. 133:15898-15901. 2011
A multivalent probe for AI-2 quorum-sensing receptors. 133:15934-15937. 2011
A practical synthesis of zanamivir phosphonate congeners with potent anti-influenza activity. 133:17959-17965. 2011
A redesigned vancomycin engineered for dual D-Ala-D-ala And D-Ala-D-Lac binding exhibits potent antimicrobial activity against vancomycin-resistant bacteria. 133:13946-13949. 2011
A substrate-free activity-based protein profiling screen for the discovery of selective PREPL inhibitors. 133:11665-11674. 2011
Activation of a water-soluble resorcinarene cavitand at the water-phosphocholine micelle interface. 133:17473-17478. 2011
Addressing the stereochemistry of complex organic molecules by density functional theory-NMR: vannusal B in retrospective. 133:6072-6077. 2011
An active-site guanine participates in glmS ribozyme catalysis in its protonated state. 133:18388-18396. 2011
An isothermal system that couples ligand-dependent catalysis to ligand-independent exponential amplification. 133:3191-3197. 2011
Atp-stimulated, DNA-mediated redox signaling by xpd, a DNA repair and transcription helicase. 133:16378-16381. 2011
Bent alkanes in a new thiourea-containing capsule. 133:10682-10684. 2011
Boronic acid hydrogen bonding in encapsulation complexes. 133:9689-9691. 2011
Catalytic asymmetric C-H insertions of rhodium(II) azavinyl carbenes. 133:10352-10355. 2011
Convergent and stereodivergent synthesis of complex 1-aza-7-oxabicyclo 2.2.1 heptanes. 133:9216-9219. 2011
Core-clickable peg-branch-azide bivalent-bottle-brush polymers by romp: Grafting-through and clicking-to. 133:559-566. 2011
Core-structure-motivated design of a phosphine-catalyzed 3+2 cycloaddition reaction: Enantioselective syntheses of spirocyclopenteneoxindoles. 133:4672-4675. 2011
Defining the rna internal loops preferred by benzimidazole derivatives via 2D combinatorial screening and computational analysis. 133:10111-10118. 2011
Design, synthesis, and validation of a β-turn mimetic library targeting protein-protein and peptide-receptor interactions. 133:10184-10194. 2011
Divergent c-h functionalizations directed by sulfonamide pharmacophores: Late-stage diversification as a tool for drug discovery. 133:7222-7228. 2011
Enantioconvergent hydroboration of a racemic allene: enantioselective synthesis of (E)-δ-stannyl-anti-homoallylic alcohols via aldehyde crotylboration. 133:5744-5747. 2011
Enantioselective dichlorination of allylic alcohols. 133:8134-8137. 2011
Enantioselective total syntheses of (-)-palau'amine, (-)-axinellamines, and (-)-massadines. 133:14710-14726. 2011
Enzymatic de novo pyrimidine nucleotide synthesis. 133:297-304. 2011
Fluoride-mediated capture of a noncovalent bound state of a reversible covalent enzyme inhibitor: X-ray crystallographic analysis of an exceptionally potent α-ketoheterocycle inhibitor of fatty acid amide hydrolase. 133:4092-4100. 2011
Functional virus-based polymer-protein nanoparticles by atom transfer radical polymerization. 133:9242-9245. 2011
Highly convergent total synthesis of (+)-lithospermic acid via a late-stage intermolecular C-H olefination. 133:5767-5769. 2011
Highly efficient hydrogen-bonding catalysis of the diels-alder reaction of 3-vinylindoles and methyleneindolinones provides carbazolespirooxindole skeletons. 133:12354-12357. 2011
Impact of distinct chemical structures for the development of a methamphetamine vaccine. 133:6587-6595. 2011
Incorporation of fluorotyrosines into ribonucleotide reductase using an evolved, polyspecific aminoacyl-tRNA synthetase. 133:15942-15945. 2011
Inverse electron demand Diels-Alder reactions of 1,2,3-triazines: Pronounced substituent effects on reactivity and cycloaddition scope. 133:12285-12292. 2011
Iterative in situ click chemistry assembles a branched capture agent and allosteric inhibitor for akt1. 133:18280-18288. 2011
Ligand-accelerated cross-coupling of C(sp2)-H bonds with arylboron reagents. 133:18183-18193. 2011
Ligand-promoted c-3 selective c-h olefination of pyridines with pd catalysts. 133:6964-6967. 2011
Ligand-promoted c3-selective arylation of pyridines with pd catalysts: Gram-scale synthesis of (+/-)-preclamol. 133:19090-19093. 2011
Light-induced conformational change and product release in DNA repair by (6-4) photolyase. 133:2183-2191. 2011
Mechanistic rationalization of organocatalyzed conjugate addition of linear aldehydes to nitro-olefins. 133:8822-8825. 2011
Multifunctional compact zwitterionic ligands for preparing robust biocompatible semiconductor quantum dots and gold nanoparticles. 133:9480-9496. 2011
Organocatalytic, enantioselective intramolecular [6+2] cycloaddition reaction for the formation of tricyclopentanoids and insight on its mechanism from a computational study. 133:20175-20185. 2011
Pd(II)-catalyzed enantioselective C-H activation of cyclopropanes. 133:19598-19601. 2011
Pd(ii)-catalyzed para-selective c-h arylation of monosubstituted arenes. 133:13864-13867. 2011
Pd-catalyzed intermolecular C-H amination with alkylamines. 133:7652-7655. 2011
Potent and selective inhibitors of glutathione S-transferase omega 1 that impair cancer drug resistance. 133:16605-16616. 2011
Practical C-H functionalization of quinones with boronic acids. 133:3292-3295. 2011
Scalable synthesis of cortistatin A and related structures. 133:8014-8027. 2011
Scalable, stereocontrolled total syntheses of (±)-axinellamines A and B. 133:13922-13925. 2011
Self-assembling small molecules form nanofibrils that bind procaspase-3 to promote activation. 133:19630-19633. 2011
Site-specific labeling of DNA and rna using an efficiently replicated and transcribed class of unnatural base pairs. 133:19878-19888. 2011
Spatiotemporal multicolor labeling of individual cells using peptide-functionalized quantum dots and mixed delivery techniques. 133:10482-10489. 2011
Stepwise synthesis of giant unilamellar vesicles on a microfluidic assembly line. 133:2798-2800. 2011
Synthesis and characterization of the arylomycin lipoglycopeptide antibiotics and the crystallographic analysis of their complex with signal peptidase. 133:17869-17877. 2011
Synthesis and molecular modeling provide insight into a Pseudomonas aeruginosa quorum sensing conundrum. 133:3840-3842. 2011
Synthesis and stereochemical determination of complestatin A and B (neuroprotectin A and B). 133:18495-18502. 2011
Synthesis of a trimeric gp120 epitope mimic conjugated to a t-helper peptide to improve antigenicity. 133:3230-3233. 2011
Synthesis of the C′D′E′F′ domain of maitotoxin. 133:214-219. 2011
Synthesis of the wxyza ' domain of maitotoxin. 133:220-226. 2011
Theoretical study of hydrogen bonding in homodimers and heterodimers of amide, boronic acid, and carboxylic acid, free and in encapsulation complexes. 133:16977-16985. 2011
Total synthesis and structural revision of the piperarborenines via sequential cyclobutane C-H arylation. 133:19076-19079. 2011
Total synthesis of epicoccin G. 133:8150-8153. 2011
Translational diffusion of macromolecular assemblies measured using transverse-relaxation-optimized pulsed field gradient NMR. 133:16354-16357. 2011
A concise enantioselective synthesis of the chlorosulfolipid malhamensilipin A. 132:2542-2543. 2010
Bioorthogonal chemical reporters for monitoring protein acetylation. 132:3640-3641. 2010
Cu(I)-amido complexes in the Ullmann reaction: reactions of Cu(I)-amido complexes with iodoarenes with and without autocatalysis by CuI. 132:15860-15863. 2010
Easy access to a family of polymer catalysts from modular star polymers. 132:2570-2572. 2010
Enzyme-catalyzed transfer of a ketone group from an S-adenosylmethionine analogue: a tool for the functional analysis of methyltransferases. 132:3642-3643. 2010
Expanding the chemistry of DNA for in vitro selection. 132:4141-4151. 2010
Expanding the dipeptidyl peptidase 4-regulated peptidome via an optimized peptidomics platform. 132:3819-3830. 2010
Gold-catalyzed three-component coupling: oxidative oxyarylation of alkenes. 132:8885-8887. 2010
Iron-catalyzed Suzuki-Miyaura coupling of alkyl halides. 132:10674-10676. 2010
Mechanism of the enantioselective oxidation of racemic secondary alcohols catalyzed by chiral Mn(III)-salen complexes. 132:11165-11170. 2010
Molecular analysis of carbohydrate-antibody interactions: case study using a Bacillus anthracis tetrasaccharide.. 132:10239-10241. 2010
Nickel-catalyzed alkenylative cross-coupling reaction of alkyl sulfides. 132:13117-13119. 2010
Pd-catalyzed O-arylation of ethyl acetohydroximate: synthesis of O-arylhydroxylamines and substituted benzofurans. 132:9990-9991. 2010
Rapid visualization and large-scale profiling of bacterial lipoproteins with chemical reporters. 132:10628-10629. 2010
Selective assembly of a high stability AAB collagen heterotrimer. 132:3242-3243. 2010
Self-assembling multidomain peptide hydrogels: designed susceptibility to enzymatic cleavage allows enhanced cell migration and spreading. 132:3217-3223. 2010
Structural consequences of β-amino acid preorganization in a self-assembling α/β-peptide: fundamental studies of foldameric helix bundles. 132:12378-12387. 2010
Total synthesis of (+/-)- and (-)-actinophyllic acid. 132:4894-4906. 2010
Total synthesis of enantiopure phalarine via a stereospecific Pictet-Spengler reaction: traceless transfer of chirality from L-tryptophan. 132:8506-8512. 2010
Total synthesis of the antimitotic bicyclic peptide celogentin C. 132:1159-1171. 2010
A bacteriophage-based platform for rapid trace detection of proteases. 132:13126-13128. 2010
A stilbene that binds selectively to transthyretin in cells and remains dark until it undergoes a chemoselective reaction to create a bright blue fluorescent conjugate. 132:16043-16051. 2010
A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity. 132:1359-1370. 2010
Acceleration of nucleophilic ch activation by strongly basic solvents. 132:12542-12545. 2010
Activity-based probes that target functional subclasses of phospholipases in proteomes. 132:3264-3265. 2010
Asymmetric total synthesis of vindoline. 132:3685-3687. 2010
Asymmetric total synthesis of vindorosine, vindoline, and key vinblastine analogues. 132:13533-13544. 2010
Biocompatible copper(I) catalysts for in vivo imaging of glycans. 132:16893-16899. 2010
Botulinum neurotoxin a protease: Discovery of natural product exosite inhibitors. 132:2868-2869. 2010
Chemoselective reductive cross-coupling of 1,5-diene-3-ols with alkynes: A facile entry to stereodefined skipped trienes. 132:9576-9578. 2010
Conserved binding mode of human beta(2) adrenergic receptor inverse agonists and antagonist revealed by X-ray crystallography. 132:11443-11445. 2010
Context-dependent effects of asparagine glycosylation on Pin WW folding kinetics and thermodynamics. 132:15359-15367. 2010
Differential receptor binding affinities of influenza hemagglutinins on glycan arrays. 132:14849-14856. 2010
Dimeric quinidine-catalyzed enantioselective aminooxygenation of oxindoles: An organocatalytic approach to 3-hydroxyoxindole derivatives. 132:5574-5575. 2010
Direct C-H arylation of electron-deficient heterocycles with arylboronic acids. 132:13194-13196. 2010
Enantioselective synthesis of (E)-delta-stannyl homoallylic alcohols via aldehyde allylboration using alpha-stannylallylboranes generated by allene hydroboration followed by a highly diastereoselective 1,3-boratropic shift. 132:7881-7883. 2010
Enediyne antitumor antibiotic maduropeptin biosynthesis featuring a c-methyltransferase that acts on a coa-tethered aromatic substrate. 132:12534-12536. 2010
Functional characterization of ttnd and ttnf, unveiling new insights into tautomycetin biosynthesis. 132:6663-6671. 2010
Glycan array on aluminum oxide-coated glass slides through phosphonate chemistry. 132:13371-13380. 2010
Intramolecular 1+2 and 3+2 cycloaddition reactions of cyclopropenone ketals. 132:8527-8529. 2010
Ligand-accelerated C-H activation reactions: evidence for a switch of mechanism. 132:14137-14151. 2010
Modulating heme redox potential through protein-induced porphyrin distortion. 132:12794-12795. 2010
Mri detection of vegfr2 in vivo using a low molecular weight peptoid-(gd)(8)-dendron for targeting. 132:12829-12831. 2010
Multidentate poly(ethylene glycol) ligands provide colloidal stability to semiconductor and metallic nanocrystals in extreme conditions. 132:9804-9813. 2010
Nitric oxide synthase stabilizes the tetrahydrobiopterin cofactor radical by controlling its protonation state. 132:11812-11823. 2010
Nosa catalyzing carboxyl-terminal amide formation in nosiheptide maturation via an enamine dealkylation on the serine-extended precursor peptide. 132:16324-16326. 2010
Pd(II)-catalyzed carbonylation of C(sp3)-H bonds: a new entry to 1,4-dicarbonyl compounds. 132:17378-17380. 2010
Pd(II)-catalyzed enantioselective C-H olefination of diphenylacetic acids. 132:460-461. 2010
Pd(II)-catalyzed hydroxyl-directed C-H olefination enabled by monoprotected amino acid ligands. 132:5916-5921. 2010
Pd(II)-catalyzed olefination of sp(3) C-H bonds. 132:3680-3681. 2010
Pd(ii)-catalyzed hydroxyl-directed c-h activation/c-o cyclization: Expedient construction of dihydrobenzofurans. 132:12203-12205. 2010
Pd(ii)-catalyzed ortho-trifluoromethylation of arenes using tfa as a promoter. 132:3648-3649. 2010
Polyketide assembly by alkene-alkyne reductive cross-coupling: Spiroketals through the union of homoallylic alcohols. 132:7602-7604. 2010
Pterin-centered radical as a mechanistic probe of the second step of nitric oxide synthase. 132:5105-5113. 2010
Rapid covalent ligation of fluorescent peptides to water solubilized quantum dots. 132:10027-10033. 2010
Recognition of the ring-opened state of proliferating cell nuclear antigen by replication factor c promotes eukaryotic clamp-loading. 132:7372-7378. 2010
Ru-porphyrin protein scaffolds for sensing o(2). 132:5582-5583. 2010
Scalable total syntheses of N-linked tryptamine dimers by direct indole-aniline coupling: Psychotrimine and kapakahines B and F. 132:7119-7137. 2010
Selective recognition and extraction of the uranyl ion. 132:13572-13574. 2010
Self-assembled quantum dot-sensitized multivalent DNA photonic wires. 132:18177-18190. 2010
Simple reagents for direct halonium-induced polyene cyclizations. 132:14303-14314. 2010
Supramolecular control of fluorescence through reversible encapsulation. 132:9984-9985. 2010
Synthesis and characterization of a cyclobutane duocarmycin derivative incorporating the 1,2,10,11-tetrahydro-9H-cyclobuta[c]benzo[e]indol-4-one (CbBI) alkylation subunit. 132:13936-13940. 2010
Synthesis and reactivity of rhodium(ii) n-triflyl azavinyl carbenes. 132:2510-2511. 2010
Synthesis of the ABCDEFG ring system of maitotoxin. 132:6855-6861. 2010
Synthesis of the QRSTU domain of maitotoxin and its 85-epi- and 86-epi-diastereoisomers. 132:9900-9907. 2010
Synthetic applications of Pd(II)-catalyzed C-H carboxylation and mechanistic insights: expedient routes to anthranilic acids, oxazolinones, and quinazolinones. 132:686-693. 2010
Tailored ligand acceleration of the Cu-catalyzed azide-alkyne cycloaddition reaction: practical and mechanistic implications. 132:14570-14576. 2010
Total synthesis and biological evaluation of the resveratrol-derived polyphenol natural products hopeanol and hopeahainol a. 132:7540-7548. 2010
Total synthesis and evaluation of a key series of C5-substituted vinblastine derivatives. 132:8489-8495. 2010
Total synthesis and structural revision of vannusals A and B: synthesis of the originally assigned structure of vannusal B. 132:7138-7152. 2010
Total synthesis and structural revision of vannusals A and B: synthesis of the true structures of vannusals A and B. 132:7153-7176. 2010
Total synthesis of (+)-fendleridine (aspidoalbidine) and (+)-1-acetylaspidoalbidine. 132:3009-3012. 2010
Total synthesis of complestatin: development of a Pd(0)-mediated indole annulation for macrocyclization. 132:7776-7783. 2010
Total synthesis of echinopines a and b. 132:3815-3818. 2010
Total synthesis of englerin a. 132:8219-8222. 2010
Total synthesis of lehualide b by allylic alcohol-alkyne reductive cross-coupling. 132:11422-11424. 2010
Total synthesis of sporolide B and 9-epi-sporolide B. 132:11350-11363. 2010
Total synthesis, assignment of the relative and absolute stereochemistry, and structural reassignment of phostriecin (aka Sultriecin). 132:2157-2159. 2010
Tyrosine bioconjugation through aqueous ene-type reactions: A click-like reaction for tyrosine. 132:1523-1525. 2010
Unusual inverse temperature dependence on reaction rate in the asymmetric autocatalytic alkylation of pyrimidyl aldehydes. 132:15104-15107. 2010
Unusual reversal of enantioselectivity in the proline-mediated alpha-amination of aldehydes induced by tertiary amine additives. 132:7598-7899. 2010
Visualizing the reaction coordinate of an O-GlcNAc hydrolase. 132:1807-1809. 2010
An antibody-recruiting small molecule that targets HIV gp120. 131:16392-+. 2009
An α/β-peptide helix bundle with a pure β3-amino acid core and a distinctive quaternary structure. 131:9860-9861. 2009
Buckled membranes in mixed-valence ionic amphiphile vesicles. 131:12030-12031. 2009
Chiral Brønsted acid-catalyzed enantioselective alpha-hydroxylation of beta-dicarbonyl compounds. 131:4562-4563. 2009
Complex polycyclic lactams from pericyclic cascade reactions of Zincke aldehydes. 131:7546-7547. 2009
Conditional RNA interference mediated by allosteric ribozyme. 131:13906-13907. 2009
Consecutive intramolecular hydroamination/asymmetric transfer hydrogenation under relay catalysis of an achiral gold complex/chiral Bronsted acid binary system. 131:9182-+. 2009
EPR and ENDOR characterization of the reactive intermediates in the generation of NO by cryoreduced oxy-nitric oxide synthase from Geobacillus stearothermophilus. 131:14493-14507. 2009
Efficient access to the core of the Strychnos, Aspidosperma and Iboga alkaloids. A short synthesis of norfluorocurarine. 131:3472-3473. 2009
Escherichia coli allows efficient modular incorporation of newly isolated quinomycin biosynthetic enzyme into echinomycin biosynthetic pathway for rational design and synthesis of potent antibiotic unnatural natural product. 131:9347-9353. 2009
Identification of an overabundant cholesterol precursor in hepatitis B virus replicating cells by untargeted lipid metabolite profiling. 131:5030-5031. 2009
Imaging of mRNA in live cells using nucleic acid-templated reduction of azidorhodamine probes. 131:6492-6497. 2009
In vitro imaging and in vivo liver targeting with carbohydrate capped quantum dots. 131:2110-2112. 2009
Lipid membrane adhesion and fusion driven by designed, minimally multivalent hydrogen-bonding lipids. 131:16919-16926. 2009
Organocatalytic synthesis of spiro[pyrrolidin-3,3'-oxindoles] with high enantiopurity and structural diversity. 131:13819-13825. 2009
Relative stereochemistry determination and synthesis of the major chlorosulfolipid from Ochromonas danica. 131:7570-7572. 2009
Relaxation dynamics of Pseudomonas aeruginosa Re(I)(CO)3(alpha-diimine)(HisX)(+) (X = 83, 107, 109, 124, 126)Cu(II) azurins. 131:11788-11800. 2009
Ring-closing metathesis of allylsilanes/electrophilic desilylation to prepare exo-methylidenecycloalkanes. Short syntheses of teucladiol and poitediol. 131:15090-15091. 2009
Stereoselective synthesis and osteogenic activity of subglutinols A and B. 131:3192-3194. 2009
Synthesis of S-linked alpha(2-->9) octasialic acid via exclusive alpha S-glycosidic bond formation. 131:3138-3139. 2009
Total synthesis of (-)-acutumine. 131:6674-6675. 2009
Toward homogeneous erythropoietin: chemical synthesis of the Ala1-Gly28 glycopeptide domain by "alanine" ligation. 131:5438-5443. 2009
"Too small, too big, and just right" - optical sensing of molecular conformations in self-assembled capsules. 131:13190-13191. 2009
A convergent stereoselective synthesis of quinolizidines and indolizidines: Chemoselective coupling of 2-hydroxymethyl-substituted allylic silanes with imines. 131:17548-17549. 2009
A short and efficient synthesis of (-)-7-methylomuralide, a potent proteasome inhibitor. 131:5746-5747. 2009
A suite of activity-based probes for human cytochrome P450 enzymes. 131:10692-10700. 2009
Bifunctional acyltransferase/decarboxylase lnmk as the missing link for beta-alkylation in polyketide biosynthesis. 131:6900-6901. 2009
Binding and inactivation mechanism of a humanized fatty acid amide hydrolase by alpha-ketoheterocycle inhibitors revealed from cocrystal structures. 131:10497-10506. 2009
Boron nitride nanotubes are noncytotoxic and can be functionalized for interaction with proteins and cells. 131:890-891. 2009
Buckyballs meet viral nanoparticles: Candidates for biomedicine. 131:17093-17095. 2009
Characterization of the sgcf epoxide hydrolase supporting an (r)-vicinal diol intermediate for enediyne antitumor antibiotic c-1027 biosynthesis. 131:16410-16417. 2009
Concise synthesis of iminocyclitols via petasis-type aminocyclization. 131:8352-8353. 2009
Controlling the specificity of modularly assembled small molecules for RNA via ligand module spacing: Targeting the RNAs that cause myotonic muscular dystrophy. 131:17464-17472. 2009
Defining the mode of action of tetramic acid antibacterials derived from Pseudomonas aeruginosa quorum sensing signals. 131:14473-14479. 2009
Design, synthesis, and evaluation of an α-helix mimetic library targeting protein-protein interactions. 131:5564-5572. 2009
Design, synthesis, biological evaluation, and structural characterization of potent histone deacetylase inhibitors based on cyclic alpha/beta-tetrapeptide architectures. 131:3033-3041. 2009
Direct observation of an enamine intermediate in amine catalysis. 131:18206-18207. 2009
Direct observation of ligand dynamics in cytochrome c. 131:6054-6055. 2009
Direct observation of structural heterogeneity in a β-sheet. 131:5726-5727. 2009
Discovery of inhibitors of aberrant gene transcription from libraries of DNA binding molecules: Inhibition of LEF-1-mediated gene transcription and oncogenic transformation. 131:3342-3348. 2009
Enantioselective intramolecular Friedel−Crafts-type α-arylation of aldehydes. 131:2086-2087. 2009
Enantioselective synthesis of 2-methyl-1,2-syn- and 2-methyl-1,2-anti-3-butenediols via allene hydroboration-aldehyde allylboration reaction sequences. 131:14602-14603. 2009
Enantioselective total synthesis of (-)-napyradiomycin A1 via asymmetric chlorination of an isolated olefin. 131:5744-5745. 2009
Enantiospecific total syntheses of kapakahines B and F. 131:6360-6361. 2009
Enzymatic synthesis and structural characterization of 13C, 15N-poly(ADP-ribose). 131:14571-14578. 2009
Evolution of proteins with genetically encoded "chemical warheads". 131:9616-9617. 2009
Explorations into neolignan biosynthesis: concise total syntheses of helicterin B, helisorin, and helisterculin A from a common intermediate. 131:1745-1752. 2009
Genetic incorporation of a metal-ion chelating amino acid into proteins as a biophysical probe. 131:2481-2483. 2009
Genetic incorporation of a small, environmentally sensitive, fluorescent probe into proteins in Saccharomyces cerevisiae. 131:12921-12923. 2009
Identification of a new endogenous metabolite and the characterization of its protein interactions through an immobilization approach. 131:378-386. 2009
Invariant polymorphism in virus capsid assembly. 131:2606-2614. 2009
Lactimidomycin, iso-migrastatin and related glutarimide-containing 12-membered macrolides are extremely potent inhibitors of cell migration. 131:1370-1371. 2009
Microfluidic device for single-molecule experiments with enhanced photostability. 131:13610-13612. 2009
Mixing and matching detergents for membrane protein NMR structure determination. 131:7320-7326. 2009
NMR characterization of membrane protein-detergent micelle solutions by use of microcoil equipment. 131:18450-18456. 2009
New synthetic technologies for the construction of heterocycles and tryptamines. 131:3690-3699. 2009
Optimization of an unnatural base pair toward natural-like replication. 131:3246-3252. 2009
Oxy-functionalization of nucleophilic rhenium(I) metal carbon bonds catalyzed by selenium(IV). 131:2466-2468. 2009
PCR with an expanded genetic alphabet. 131:14620-14621. 2009
Pd(0)/PR(3)-catalzed intermolecular arylation of sp(3) C-H bonds. 131:9886-9887. 2009
Pd(II)-catalyzed amination of C-H bonds using single-electron or two-electron oxidants. 131:10806-10807. 2009
Pd(ii)-catalyzed hydroxylation of arenes with 1 atm of o(2) or air. 131:14654-14655. 2009
Pd(ii)-catalyzed olefination of electron-deficient arenes using 2,6-dialkylpyridine ligands. 131:5072-5074. 2009
Possible origin of electronic effects in rh(i)-catalyzed enantioselective hydrogenation. 131:9604-9605. 2009
Prediction of the rotational tumbling time for proteins with disordered segments. 131:6814-6821. 2009
Probing synergy between two catalytic strategies in the glycoside hydrolase O-GlcNAcase using multiple linear free energy relationships. 131:13415-13422. 2009
Probing the dynamics of the p1 helix within the tetrahymena group i intron. 131:9571-9578. 2009
Probing the folding transition state structure of the villin headpiece subdomain via side chain and backbone mutagenesis. 131:7470-7476. 2009
Product protection, the key to developing high performance methane selective oxidation catalysts. 131:17110-17115. 2009
Pseudo-capsule assemblies characterized by (19)f NMR techniques. 131:2440-2441. 2009
Rational design of ligands targeting triplet repeating transcripts that cause RNA dominant disease: Application to myotonic muscular dystrophy type 1 and spinocerebellar ataxia type 3. 131:9767-9779. 2009
Recognition and organocatalysis with a synthetic cavitand receptor. 131:7402-7410. 2009
Revisiting AI-2 quorum sensing inhibitors: Direct comparison of alkyl-DPD analogues and a natural product fimbrolide. 131:15584-15585. 2009
Rhodium-catalyzed enantioselective cyclopropanation of olefins with N-sulfonyl 1,2,3-triazoles. 131:18034-18035. 2009
Scalable total synthesis and biological evaluation of haouamine a and its atropisomer. 131:9172-9173. 2009
Selective toxin sequestrants for the treatment of bacterial infections. 131:5760-5762. 2009
Stereoselective synthesis of gamma-substituted (Z)-allylic boranes via kinetically controlled hydroboration of allenes with 10-TMS-9-borabicyclo[3.3.2]decane. 131:14174-14175. 2009
Synthesis at the interface of chemistry and biology. 131:12497-12515. 2009
Tandem application of virtual screening and NMR experiments in the discovery of brand new DNA quadruplex groove binders. 131:16336-16337. 2009
The second step of the nitric oxide synthase reaction: Evidence for ferric-peroxo as the active oxidant. 131:297-305. 2009
Thiol-selective fluorogenic probes for labeling and release. 131:9986-9994. 2009
Thiourea-catalyzed highly enantio- and diastereoselective additions of oxindoles to nitroolefins: Application to the formal synthesis of (+)-physostigmine. 131:8758-8759. 2009
Total syntheses of (+/-)-platencin and (-)-platencin. 131:15909-15917. 2009
Total synthesis and biological evaluation of (+)- and (-)-bisanthraquinone antibiotic BE-43472B and related compounds. 131:14812-14826. 2009
Total synthesis and biological evaluation of cortistatins a and j and analogues thereof. 131:10587-10597. 2009
Total synthesis and evaluation of iso-duocarmycin SA and iso-yatakemycin. 131:1187-1194. 2009
Total synthesis and structure elucidation of (+)-phorbasin c. 131:1392-1393. 2009
Total synthesis of chloropeptin II (complestatin) and chloropeptin I. 131:16036-16038. 2009
Total synthesis of diverse carbogenic complexity within the resveratrol class from a common building block. 131:1753-1765. 2009
Total synthesis of platensimycin and related natural products. 131:16905-16918. 2009
Total synthesis of vinblastine, vincristine, related natural products, and key structural analogues. 131:4904-4916. 2009
Total synthesis of vinigrol. 131:17066-17067. 2009
Transcription of an expanded genetic alphabet. 131:5046-5047. 2009
Transition-state charge transfer reveals electrophilic, ambiphilic, and nucleophilic carbon-hydrogen bond activation. 131:11686-11688. 2009
Universal translators for nucleic acid diagnosis. 131:9368-9377. 2009
Versatile Pd(OTf)2 x 2 H2O-catalyzed ortho-fluorination using NMP as a promoter. 131:7520-7521. 2009
A global metabolite profiling approach to identify protein-metabolite interactions. 130:14111-14113. 2008
A templating approach for monodisperse self-assembled organic nanostructures. 130:2742-2743. 2008
Analysis of the cryptophycin P450 epoxidase reveals substrate tolerance and cooperativity. 130:5492-5498. 2008
Application of affinity selection/mass spectrometry to determine the structural isomer of parnafungins responsible for binding polyadenosine polymerase. 130:16704-16710. 2008
Enantioselective total syntheses of nankakurines A and B: confirmation of structure and establishment of absolute configuration. 130:11297-11299. 2008
Engineering complex riboswitch regulation by dual genetic selection. 130:16310-16315. 2008
Fluorescent profiling of modular biosynthetic enzymes by complementary metabolic and activity based probes. 130:5443-5445. 2008
Functional determinants of a synthetic vesicle fusion system. 130:6196-6205. 2008
Genetically encoding protein oxidative damage. 130:4028-4033. 2008
Intra- and intermembrane pairwise molecular recognition between synthetic hydrogen-bonding phospholipids. 130:14456-14458. 2008
Minimally cationic cell-permeable miniature proteins via α-helical arginine display. 130:2948-2949. 2008
Origins of enhanced proton transport in the Y7F mutant of human carbonic anhydrase II. 130:11399-11408. 2008
Self-assembling peptide coatings designed for highly luminescent suspension of single-walled carbon nanotubes. 130:17134-17140. 2008
Self-assembly of α-helical coiled coil nanofibers. 130:13691-13695. 2008
Solution phase measurement of both weak sigma and C-H center dot center dot center dot X- hydrogen bonding interactions in synthetic anion receptors. 130:10895-10897. 2008
Stereocontrolled synthesis of Z-dienes via an unexpected pericyclic cascade rearrangement of 5-amino-2,4-pentadienals. 130:7560-7561. 2008
Stereoselective dichlorination of allylic alcohol derivatives to access key stereochemical arrays of the chlorosulfolipids. 130:12514-12518. 2008
Synthetic collagen heterotrimers: structural mimics of wild-type and mutant collagen type I. 130:7509-7515. 2008
Time-resolved dimerization of a PAS-LOV protein measured with photocoupled small angle X-ray scattering. 130:12226-12227. 2008
Total synthesis and molecular target of largazole, a histone deacetylase inhibitor. 130:8455-8459. 2008
Total synthesis of (+/-)-actinophyllic acid. 130:7568-7569. 2008
1,3-diol synthesis via controlled, radical-mediated C-H functionalization. 130:7247-7249. 2008
A concise asymmetric total synthesis of aspidophytine. 130:14942-14943. 2008
A general and efficient method for the site-specific dual-labeling of proteins for single molecule fluorescence resonance energy transfer. 130:17664-17665. 2008
A peptoid "antibody surrogate" that antagonizes VEGF receptor 2 activity. 130:5744-5752. 2008
A single-molecule nanopore device detects DNA polymerase activity with single-nucleotide resolution. 130:818-820. 2008
An additional spirocyclization for duocarmycin SA. 130:16521-16523. 2008
An expedient asymmetric synthesis of platencin. 130:11292-11293. 2008
An unexpected switch in the modulation of AI-2-based quorum sensing discovered through synthetic 4,5-dihydroxy-2,3-pentanedione analogues. 130:9200-9201. 2008
Bifunctional CD22 ligands use multimeric immunoglobulins as protein scaffolds in assembly of immune complexes on B cells. 130:7736-7745. 2008
Biosynthesis of a site-specific DNA cleaving protein. 130:13194-13195. 2008
Carbon-deuterium bonds as probes of dihydrofolate reductase. 130:6597-6603. 2008
Catalysis of 3-pyrrolidinecarboxylic acid and related pyrrolidine derivatives in enantioselective anti-mannich-type reactions: Importance of the 3-acid group on pyrrolidine for stereocontrol. 130:875-886. 2008
Characterization of the two-component, fad-dependent monooxygenase sgcc that requires carrier protein-tethered substrates for the biosynthesis of the enediyne antitumor antibiotic c-1027. 130:6616-6623. 2008
Chemical synthesis and biological evaluation of palmerolide a analogues. 130:10019-10023. 2008
Chemical synthesis of a glycoprotein having an intact human complex-type sialyloligosaccharide under the Boc and Fmoc synthetic strategies. 130:501-510. 2008
Chemical synthesis of the GHIJKLMNO ring system of maitotoxin. 130:7466-7476. 2008
Conversion of allylic alcohols to stereodefined trisubstituted alkenes: A complementary process to the claisen rearrangement. 130:16870-16872. 2008
Design, synthesis, and biological evaluation of platensimycin analogues with varying degrees of molecular complexity. 130:13110-13119. 2008
Direct coupling of catharanthine and vindoline to provide vinblastine: Total synthesis of (+)- and ent-(-)-vinblastine. 130:420-421. 2008
Discovery, characterization, and optimization of an unnatural base pair for expansion of the genetic alphabet. 130:2336-2343. 2008
Emergence of a single solid chiral state from a nearly racemic amino acid derivative. 130:1158-1159. 2008
Enantiospecific total synthesis of the hapalindoles, fischerindoles, and welwitindolinones via a redox economic approach. 130:17938-17954. 2008
Evolution of solid phase homochirality for a proteinogenic amino acid. 130:15274-15275. 2008
In situ generation of a bisubstrate analogue for protein arginine methyltransferase 1. 130:4574-4575. 2008
In vivo incorporation of unnatural amino acids to probe structure, dynamics, and ligand binding in a large protein by nuclear magnetic resonance spectroscopy. 130:9268-9281. 2008
Influence of remote asymmetric centers in reversible encapsulation complexes. 130:2450-2451. 2008
Interactions between redox complexes and semiconductor quantum dots coupled via a peptide bridge. 130:16745-16756. 2008
Intermolecular enolate heterocoupling: Scope, mechanism, and application. 130:11546-11560. 2008
Microscale NMR screening of new detergents for membrane protein structural biology. 130:7357-7363. 2008
On-virus construction of polyvalent glycan ligands for cell-surface receptors. 130:4578-4579. 2008
Optimization of activity-based probes for proteomic profiling of histone deacetylase complexes. 130:2184-2194. 2008
Organocatalysis in a synthetic receptor with an inwardly directed carboxylic acid. 130:5658-5659. 2008
Pd(II)-catalyzed cross-coupling of sp3 C-H Bonds with sp2 and sp3 boronic acids using air as the oxidant. 130:7190-7191. 2008
Plasma clearance of bacteriophage Qβ particles as a function of surface charge. 130:1328-1334. 2008
Quantitative microarray analysis of intact glycolipid-CD1d interaction and correlation with cell-based cytokine production. 130:12348-12354. 2008
Reaction of carboxylic acids and isonitriles in small spaces. 130:7810-7811. 2008
Reaction of isonitriles with carboxylic acids in a cavitand: Observation of elusive isoimide intermediates. 130:11850-11851. 2008
Rhodium-catalyzed transannulation of 1,2,3-triazoles with nitriles. 130:14972-14974. 2008
Ruthenium-catalyzed azide-alkyne cycloaddition: scope and mechanism. 130:8923-8930. 2008
Selecting folded proteins from a library of secondary structural elements. 130:176-185. 2008
Sialoside analogue arrays for rapid identification of high affinity siglec ligands. 130:6680-6681. 2008
Stability, dynamics, and selectivity in the assembly of hydrogen-bonded hexameric capsules. 130:2344-2350. 2008
Sugar-assisted glycopeptide ligation with complex oligosaccharides: Scope and limitations. 130:11945-11952. 2008
Synthesis of (+)-cortistatin A. 130:7241-7243. 2008
Synthesis of 1,2- and 1,3-dicarboxylic acids via Pd(II)-catalyzed carboxylation of aryl and vinyl C-H bonds. 130:14082-14083. 2008
Synthesis of β-, γ-, and δ-Lactams via Pd(II)-catalyzed C−H activation reaction. 130:14058-14059. 2008
Targeting large kinase active site with rigid, bulky octahedral ruthenium complexes. 130:15764-5. 2008
The role of tandem acyl carrier protein domains in polyunsaturated fatty acid biosynthesis. 130:6336-6337. 2008
The structure of a TNA-TNA complex in solution: NMR study of the octamer duplex derived from alpha-(L)-threofuranosyl-(3 '-2 ')-CGAATTCG. 130:15105-15115. 2008
Total syntheses of (+)-tedanolide and (+)-13-deoxytedanolide. 130:16407-16416. 2008
Total syntheses of (+/-)-massadine and massadine chloride. 130:16490-16491. 2008
Total synthesis of (+)-superstolide A. 130:2722-2723. 2008
Total synthesis of (+/-)-psychotrimine. 130:10886-10887. 2008
Total synthesis of biologically active natural products. 130:6654-6656. 2008
Total synthesis of chlorofusin, its seven chromophore diastereomers, and key partial structures. 130:12355-12369. 2008
Total synthesis of the originally proposed and revised structures of palmerolide a and isomers thereof. 130:3633-3644. 2008
Total synthesis, revised structure, and biological evaluation of biyouyanagin A and analogues thereof. 130:11114-11121. 2008
Toward a chemical mechanism of proton pumping by the B-type cytochrome c oxidases: application of density functional theory to cytochrome ba(3) of Thermus thermophilus. 130:15002-15021. 2008
Two-dimensional combinatorial screening identifies specific aminoglycoside - RNA internal loop partners. 130:11185-11194. 2008
Unnatural substrate repertoire of a, b, and x family DNA polymerases. 130:14872-14882. 2008
Versatile Pd(II)-catalyzed C-H activation/aryl-aryl coupling of benzoic and phenyl acetic acids. 130:17676-17677. 2008
A new mechanism for benzopyrone formation in aromatic polyketide biosynthesis. 129:9304-9305. 2007
Biophysical and structural characterization of a robust octameric β-peptide bundle. 129:14746-14751. 2007
Biophysical characterization of a β-peptide bundle: Comparison to natural proteins. 129:5344-5345. 2007
Design and synthesis of a BODIPY-alpha-tocopherol adduct for use as an off/on fluorescent antioxidant indicator. 129:1842-1843. 2007
Design of a functional membrane protein by engineering a heme-binding site in glycophorin A. 129:512-518. 2007
Different apolipoproteins impact nanolipoprotein particle formation. 129:14348-14354. 2007
Discrete heterogeneous quaternary structure formed by α/β-peptide foldamers and α-peptides. 129:6376-6377. 2007
Gold-catalyzed deoxygenated cyclization of cis-2,4-dien-1-als with regioselective addition of two nucleophiles. One-pot synthesis of highly functionalized cyclopentene framework. 129:3798-3799. 2007
Helix bundle quaternary structure from α/β-peptide foldamers. 129:4178-4180. 2007
High-resolution structure of a β-peptide bundle. 129:1532-1533. 2007
Highly selective Diels-Alder reactions of directly connected enyne dienophiles. 129:645-657. 2007
Intrinsically cell-permeable miniature proteins based on a minimal cationic PPII motif. 129:14578-14579. 2007
Practical synthesis of enantiomerically pure β2)-amino acids via proline-catalyzed diastereoselective aminomethylation of aldehydes. 129:6050-6055. 2007
Prediction of the 3D structure and dynamics of human DP G-protein coupled receptor bound to an agonist and an antagonist. 129:10720-10731. 2007
Reactivation of the p53 tumor suppressor pathway by a stapled p53 peptide. 129:2456-2457. 2007
Reengineering a natural riboswitch by dual genetic selection. 129:13814-13815. 2007
Self-assembled heterotrimeric collagen triple helices directed through electrostatic interactions. 129:2683-2690. 2007
Self-assembly of multidomain peptides: Balancing molecular frustration controls conformation and nanostructure. 129:12468-12472. 2007
Sila Morita-Baylis-Hillman reaction of cyclopropenes. 129:14868-14869. 2007
Surprisingly high stability of collagen ABC heterotrimer: Evaluation of side chain charge pairs. 129:15034-15041. 2007
Tethering small molecules to a phage display library: discovery of a selective bivalent inhibitor of protein kinase A. 129:13812-13813. 2007
The hydrophobic effect drives the recognition of hydrocarbons by an anionic metal-ligand cluster. 129:12094-12095. 2007
8-Azaguanine reporter of purine ionization states in structured RNAs. 129:3426-3432. 2007
A functional proteomic strategy to discover inhibitors for uncharacterized hydrolases. 129:9594-9595. 2007
A unique class of duocarmycin and CC-1065 analogues subject to reductive activation. 129:15391-15397. 2007
Alanine scan of [L-Dap2]ramoplanin A2 aglycon: Assessment of the importance of each residue. 129:8747-8755. 2007
Analysis of PUGNAc and NAG-thiazoline as transition state analogues for human O-GlcNAcase: mechanistic and structural insights into inhibitor selectivity and transition state poise. 129:635-644. 2007
Anomeric reactivity-based one-pot synthesis of heparin-like oligosaccharides. 129:12795-12800. 2007
Antibody-catalyzed oxidation of delta(9)-tetrahydrocannabinol. 129:3698-3702. 2007
Assembly and exchange of resorcinarene capsules monitored by fluorescence resonance energy transfer. 129:3818-3819. 2007
Benzimidazole and related ligands for Cu-catalyzed azide-alkyne cycloaddition. 129:12696-12704. 2007
Bifunctional catalysis of proton transfer at an antibody active site. 129:460-461. 2007
Biomimetic catalysis of intermodular aminoacyl transfer. 129:748-749. 2007
Cavitands with introverted functionality stabilize tetrahedral intermediates. 129:15639-15643. 2007
Characterization of NcsB2 as a promiscuous naphthoic acid/coenzyme A ligase integral to the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin. 129:7728-7729. 2007
Characterization of the maduropeptin biosynthetic gene cluster from actinomadura madurae atcc 39144 supporting a unifying paradigm for enediyne biosynthesis. 129:13082-13094. 2007
Clarification of the role of water in proline-mediated aldol reactions. 129:15100-15101. 2007
Contrasting two- and three-dimensional crystal properties of isomeric dialkyl phthalates. 129:15211-15217. 2007
Crystal structure of a biosynthetic sulfo-hirudin complexed to thrombin. 129:10648-10649. 2007
D-fructose-6-phosphate aldolase-catalyzed one-pot synthesis of iminocyclitols. 129:14811-14817. 2007
Design and synthesis of c5 methylated l-arginine analogues as active site probes for nitric oxide synthase. 129:12563-12570. 2007
Detection of reactive tetrahedral intermediates in a deep cavitand with an introverted functionality. 129:15330-15339. 2007
Direct catalytic asymmetric synthesis of anti-1,2-amino alcohols and syn-1,2-diols through organocatalytic anti-mannich and syn-aldol reactions. 129:288-289. 2007
Efforts toward expansion of the genetic alphabet: structure and replication of unnatural base pairs. 129:10466-10473. 2007
Emergence of solution-phase homochirality via crystal engineering of amino acids. 129:7657-7660. 2007
Enrichment tags for enhanced-resolution profiling of the polar metabolome. 129:15780-15782. 2007
Extended sugar-assisted glycopeptide ligations: Development, scope, and applications. 129:13527-13536. 2007
Extraction of hydrophobic species into a water-soluble synthetic receptor. 129:13464-13473. 2007
Fourier transform infrared characterization of a cu-b-nitrosyl complex in cytochrome ba3 from thermus thermophilus: Relevance to no reductase activity in heme-copper terminal oxidases. 129:14952-14958. 2007
Functional and mechanistic analyses of biomimetic aminoacyl transfer reactions in de novo designed coiled coil peptides via rational active site engineering. 129:2959-2966. 2007
Guest recognition with micelle-bound cavitands. 129:9773-9779. 2007
Identification of a peptoid inhibitor of the proteasome 19S regulatory particle. 129:7750-7751. 2007
In vivo site-specific DNA methylation with a designed sequence-enabled DNA methylase. 129:8676-8677. 2007
Label transfer chemistry for the characterization of protein-protein interactions. 129:12348-12349. 2007
Ligand-accelerated Cu-catalyzed azide-alkyne cycloaddition: a mechanistic report. 129:12705-12712. 2007
Methylrhenium trioxide revisited: mechanisms for nonredox oxygen insertion in an M-CH3 bond. 129:15794-15804. 2007
Minor groove hydrogen bonds and the replication of unnatural base pairs. 129:5551-5557. 2007
Modular multi-level circuits from immobilized DNA-based logic gates. 129:14875-14879. 2007
Palladium-catalyzed methylation and arylation of sp2 and sp3 C-H bonds in simple carboxylic acids. 129:3510-3511. 2007
Periodate-triggered cross-linking reveals Sug2/Rpt4 as the molecular target of a peptoid inhibitor of the 19S proteasome regulatory particle. 129:12936-12937. 2007
Quantitative analysis of carbohydrate-protein interactions using glycan microarrays: Determination of surface and solution dissociation constants. 129:11177-11184. 2007
Quantitative evaluation of the relative cell permeability of peptoids and peptides. 129:1508-1509. 2007
Rational design, synthesis, and evaluation of key analogues of CC-1065 and the duocarmycins. 129:14092-14099. 2007
Regio- and stereoselective cross-coupling of substituted olefins and imines. A convergent stereoselective synthesis of saturated 1,5-aminoalcohols and substituted piperidines. 129:7514-7516. 2007
Regiospecific chlorination of (s)-ss-tyrosyl-s-carrier protein catalyzed by sgcc3 in the biosynthesis of the enediyne antitumor antibiotic c-1027. 129:12432-12438. 2007
Remarkable loop flexibility in avian influenza N1 and its implications for antiviral drug design. 129:7764-7765. 2007
Rhenium(vii) oxide catalyzed heteroacylative ring-opening dimerization of tetrahydrofuran. 129:1246-1253. 2007
Scope and mechanism of direct indole and pyrrole couplings adjacent to carbonyl compounds: Total synthesis of acremoauxin A and oxazinin 3. 129:12857-12869. 2007
Self-assembly dynamics of a cylindrical capsule monitored by fluorescence resonance energy transfer. 129:8818-8824. 2007
Sequence-specific resonance assignment of soluble nonglobular proteins by 7D APSY-NMR Spectroscopy. 129:10823-10828. 2007
Site-specific insertion of 3-aminotyrosine into subunit α2 of E. coli ribonucleotide reductase: direct evidence for involvement of Y(730) and Y(731) in radical propagation. 129:15060-15071. 2007
Solution NMR studies of the maturation intermediates of a 13 MDa viral capsid. 129:7867-7876. 2007
Structural and initial biological analysis of synthetic arylomycin A(2). 129:15830-15838. 2007
Sugar-assisted ligation in glycoprotein synthesis. 129:7690-7701. 2007
Synthesis of 5-fluoropyrimidine nucleotides as sensitive NMR probes of RNA structure. 129:14911-14921. 2007
Synthesis of potent bicyclic bisarylimidazole c-jun N-terminal kinase inhibitors by catalytic C-H bond activation. 129:490-491. 2007
Synthesis of substituted 1,4-dienes by direct alkylation of allylic alcohols. 129:15112-15113. 2007
Synthesis of tamiflu and its phosphonate congeners possessing potent anti-influenza activity. 129:11892-11893. 2007
Systematic exploration of the structural features of yatakemycin impacting DNA alkylation and biological activity. 129:10858-10869. 2007
Tailored glycoproteomics and glycan site mapping using saccharide-selective bioorthogonal probes. 129:7266-7267. 2007
Tailoring relaxation dispersion experiments for fast-associating protein complexes. 129:13406-13407. 2007
The case of the missing ring: Radical cleavage of a carbon-carbon bond and implications for gfp chromophore biosynthesis. 129:3118-3126. 2007
The mechanism of mio-based aminomutases in beta-amino acid biosynthesis. 129:15744-15745. 2007
Total syntheses of 2,2 '-epi-cytoskyrin a, rugulosin, and the alleged structure of rugulin. 129:4001-4013. 2007
Total synthesis and antibacterial properties of carbaplatensimycin. 129:14850-14851. 2007
Total synthesis of abyssomicin c, atrop-abyssomicin c, and abyssomicin d: Implications for natural origins of atrop-abyssomicin c. 129:429-440. 2007
Total synthesis of dimeric pyrrole-imidazole alkaloids: Sceptrin, ageliferin, nagelamide e, oxysceptrin, nakamuric acid, and the axinellamine carbon skeleton. 129:4762-4775. 2007
Total synthesis of kinamycins C, F, and J. 129:10356-10357. 2007
Total synthesis of marinomycins A-C and of their monomeric counterparts monomarinomycin A and iso-monomarinomycin A. 129:1760-1768. 2007
Total synthesis, stereochemical reassignment, and absolute configuration of chlorofusin. 129:9860-9861. 2007
A simple γ-backbone modification preorganizes peptide nucleic acid into a helical structure. 128:10258-10267. 2006
An α-helical peptidomimetic inhibitor of the HIV-1 Rev-RRE interaction. 128:3496-3497. 2006
Circumventing the problems caused by protein diversity in microarrays: Implications for protein interaction networks. 128:13668-13669. 2006
Convergent, enantioselective syntheses of guanacastepenes A and E featuring a selective cyclobutane fragmentation. 128:7025-7035. 2006
Cyclic peptide helices: A hybrid beta-hairpin/beta-helical supersecondary structure. 128:10650-10651. 2006
Direct nucleophilic acylation of nitroalkenes promoted by a fluoride anion/thiourea combination. 128:4932-4933. 2006
Enantioselective TADMAP-catalyzed carboxyl migration reactions for the synthesis of stereogenic quaternary carbon. 128:925-934. 2006
Excited-state dynamics of structurally characterized [Re-I(CO)(3)(phen)(HisX)](+) (X=83,109) Pseudomonas aeruginosa azurins in aqueous solution. 128:4365-4370. 2006
Membrane activation: selective vesicle fusion via small molecule recognition. 128:14430-14431. 2006
Non-uniformly sampled double-TROSY hNcaNH experiments for NMR sequential assignments of large proteins. 128:5757-5763. 2006
Self-assembly of peptide-amphiphile nanofibers: The roles of hydrogen bonding and amphiphilic packing. 128:7291-7298. 2006
Solvent isotope effects on interfacial protein electron transfer in crystals and electrode films. 128:2346-2355. 2006
Synthesis and evaluation of bioorthogonal pantetheine analogues for in vivo protein modification. 128:12174-12184. 2006
Synthesis of taiwaniaquinoids via Nazarov triflation. 128:11022-11023. 2006
Uncovering quantitative protein interaction networks for mouse PDZ domains using protein microarrays. 128:5913-5922. 2006
"Click" chemistry in a supramolecular environment: stabilization of organogels by copper(I)-catalyzed azide-alkyne [3 + 2] cycloaddition. 128:6056-6057. 2006
3-pyrrolidinecarboxylic acid for direct catalytic asymmetric anti-Mannich-type reactions of unmodified ketones. 128:9630-9631. 2006
A fluoroacetamidine-based inactivator of protein arginine deiminase 4: Design, synthesis, and in vitro and in vivo evaluation. 128:1092-1093. 2006
A genetically encoded fluorescent amino acid. 128:8738-8739. 2006
A genetically encoded infrared probe. 128:13984-13985. 2006
A reversible reaction inside a self-assembled capsule. 128:9308-9309. 2006
A synthetic mimic of protein inner space: Buried polar interactions in a deep water-soluble host. 128:15366-15367. 2006
Activity-based protein profiling reagents for protein arginine deiminase 4 (pad4): Synthesis and in vitro evaluation of a fluorescently labeled probe. 128:14468-14469. 2006
Amide-to-E-olefin versus amide-to-ester backbone H-bond perturbations: evaluating the O-O repulsion for extracting H-bond energies. 128:15948-15949. 2006
Amino acid dependent formation of phosphate anhydrides in water mediated by carbonyl sulfide. 128:20-21. 2006
An alkoxide-directed carbometalation of internal alkynes. 128:2764-2765. 2006
An efficiently extended class of unnatural base pairs. 128:6780-6781. 2006
Antibody interference with N-acyl homoserine lactone-mediated bacterial quorum sensing. 128:2802-2803. 2006
Asymmetric total synthesis of (+)- and ent-(-)-yatakemycin and duocarmycin SA: evaluation of yatakemycin key partial structures and its unnatural enantiomer. 128:15683-15696. 2006
Carboxylic solvents and O-donor ligand effects on CH activation by Pt(II). 128:7404-7405. 2006
Cavitands with revolving doors regulate binding selectivities and rates in water. 128:3894-3895. 2006
Chemistry of periodate-mediated cross-linking of 3,4-dihydroxylphenylalanine-containing molecules to proteins. 128:15228-15235. 2006
Coiled molecules in spring loaded devices. 128:15038-15039. 2006
Concise total syntheses of palominol, dolabellatrienone, beta-araneosene, and isoedunol via an enantioselective Diels-Alder macrobicyclization. 128:740-742. 2006
Cu(ii)-catalyzed functionalizations of aryl c-h bonds using o-2 as an oxidant. 128:6790-6791. 2006
Delineation of a fundamental alpha-ketoheterocycle substituent effect for use in the design of enzyme inhibitors. 128:14004-14005. 2006
Diastereoselective Diels-Alder reactions of N-sulfonyl-1-aza-1,3-butadienes with optically active enol ethers: An asymmetric variant of the 1-azadiene Diels-Alder reaction. 128:2587-2593. 2006
Direct and high resolution characterization of cytochrome c equilibrium folding. 128:14232-14233. 2006
Direct asymmetric anti-mannich-type reactions catalyzed by a designed amino acid. 128:1040-1041. 2006
Discovery of EGFR selective 4,6-disubstituted pyrimidines from a combinatorial kinase-directed heterocycle library. 128:2182-2183. 2006
Efforts toward developing direct probes of protein dynamics. 128:6028-6029. 2006
Enantioselective total synthesis of avrainvillamide and the stephacidins. 128:8678-8693. 2006
Expanded capsules with reversibly added spacers. 128:5314-5315. 2006
Facile functionalization of a metal carbon bond by O-atom transfer. 128:9018-9019. 2006
Fluorescent sensors for organophosphorus nerve agent mimics. 128:4500-4501. 2006
Fluorescent signal amplification of carbocyanine dyes using engineered viral nanoparticles. 128:5184-5189. 2006
Infrared line shape of an alpha-carbon deuterium-labeled amino acid. 128:13334-13335. 2006
Intramolecular Diels-Alder/1,3-dipolar cycloaddition cascade of 1,3,4-oxadiazoles. 128:10589-10595. 2006
Measurement of long-range 1H-19F scalar coupling constants and their glycosidic torsion dependence in 5-fluoropyrimidine-substituted RNA. 128:5851-5858. 2006
Mechanistic implications of pseudo zero order kinetics in kinetic resolutions. 128:7450-7451. 2006
Molecular organization of cholesterol in unsaturated phosphatidylethanolamines: X-ray diffraction and solid state h-2 NMR reveal differences with phosphatidylcholines. 128:5375-5383. 2006
New RNA labeling methods offer dramatic sensitivity enhancements in 2H NMR relaxation spectra. 128:9346-9347. 2006
Nucleophilic catalysis of hydrazone formation and transimination: implications for dynamic covalent chemistry. 128:15602-15603. 2006
Optimization of unnatural base pair packing for polymerase recognition. 128:6369-6375. 2006
Organocatalytic direct asymmetric aldol reactions in water. 128:734-735. 2006
Organocatalytic direct michael reaction of ketones and aldehydes with beta-nitrostyrene in brine. 128:4966-4967. 2006
Palladium-catalyzed alkylation of aryl c-h bonds with sp(3) organotin reagents using benzoquinone as a crucial promoter. 128:78-79. 2006
Palladium-catalyzed alkylation of sp(2) and sp(3) c-h bonds with methylboroxine and alkylboronic acids: Two distinct c-h activation pathways. 128:12634-12635. 2006
Physical controls on directed virus assembly at nanoscale chemical templates. 128:10801-10807. 2006
Redox-coupled dynamics and folding in cytochrome c. 128:7909-7915. 2006
Reevaluation of the mechanism of the amination of aryl halides catalyzed by BINAP-ligated palladium complexes. 128:3584-3591. 2006
Rieske protein from thermus thermophilus: N-15 NMR titration study demonstrates the role of iron-ligated histidines in the ph dependence of the reduction potential. 128:10672-10673. 2006
Sensitive and selective detection of nitric oxide using an h-nox domain. 128:10022-10023. 2006
Structural evidence for an enolate intermediate in gfp fluorophore biosynthesis. 128:3166-3168. 2006
Structure-based discovery of glycolipids for CD1d-mediated NKT cell activation: Tuning the adjuvant versus immunosuppression activity. 128:9022-9023. 2006
Sugar-assisted glycopeptide ligation. 128:5626-5627. 2006
Sugar-assisted ligation of N-linked glycopeptides with broad sequence tolerance at the ligation junction. 128:15026-15033. 2006
Superactivation of the botulinum neurotoxin serotype A light chain metalloprotease: A new wrinkle in botulinum neurotoxin. 128:4176-4177. 2006
Synthesis of degradable model networks via atrp and click chemistry. 128:6564-6565. 2006
Synthetic seleno-glutaredoxin 3 analogues are highly reducing oxidoreductases with enhanced catalytic efficiency. 128:16684-16691. 2006
The bifunctional glyceryl transferase/phosphatase ozmb belonging to the had superfamily that diverts 1,3-bisphosphoglycerate into polyketide biosynthesis. 128:10386-10387. 2006
The genetic incorporation of a distance probe into proteins in Escherichia coli. 128:4572-4573. 2006
The incorporation of a photoisomerizable amino acid into proteins in E. coli. 128:388-389. 2006
The putative endocannabinoid transport blocker LY2183240 is a potent inhibitor of FAAH and several other brain serine hydrolases. 128:9699-9704. 2006
The two-state issue in the mixed-valence binuclear cu-a center in cytochrome c oxidase and n2o reductase. 128:16452-16453. 2006
Total synthesis and biological evaluation of halipeptins a and d and analogues. 128:4460-4470. 2006
Total synthesis and evaluation of [Ψ[CH(2)NH]Tpg(4)]vancomycin aglycon: reengineering vancomycin for dual D-Ala-D-Ala and D-Ala-D-Lac binding. 128:2885-2892. 2006
Total synthesis and evaluation of cytostatin, its C10-C11 diastereomers, and additional key analogues: Impact on PP2A inhibition. 128:16720-16732. 2006
Total synthesis and structural elucidation of azaspiracid-1. Construction of key building blocks for originally proposed structure. 128:2244-2257. 2006
Total synthesis and structural elucidation of azaspiracid-1. Final assignment and total synthesis of the correct structure of azaspiracid-1. 128:2859-2872. 2006
Total synthesis and structural elucidation of azaspiracid-1. Synthesis-based analysis of originally proposed structures and indication of their non-identity to the natural product. 128:2258-2267. 2006
Total synthesis of (+/-)-chartelline C. 128:14028-14029. 2006
Total synthesis of (+/-)-haouamine A. 128:3908-3909. 2006
Total synthesis of (-)- and ent-(+)-vindoline and related alkaloids. 128:10596-10612. 2006
Total synthesis of amphidinolide E. 128:15960-15961. 2006
Total synthesis of piericidin A1 and B1 and key analogues. 128:11799-11807. 2006
Understanding GFP posttranslational chemistry: Structures of designed variants that achieve backbone fragmentation, hydrolysis, and decarboxylation. 128:4685-4693. 2006
Unexpected acetylcholinesterase activity of cocaine esterases. 128:15364-15365. 2006
Biomimetic synthesis of antimalarial naphthoquinones. 127:6276-6283. 2005
Conformational substates modulate hydride transfer in dihydrofolate reductase. 127:12997-13006. 2005
Design, synthesis, and biological evaluation of HSP90 inhibitors based on conformational analysis of radicicol and its analogues. 127:6999-7004. 2005
Determination of the packing mode of the coiled-coil domain of cGMP-Dependent protein kinase I alpha in solution using charge-predicted dipolar couplings. 127:11918-11919. 2005
Importance of tensor asymmetry for the analysis of (2)H NMR spectra from deuterated aromatic rings. 127:17488-17493. 2005
In vivo reporter labeling of proteins via metabolic delivery of coenzyme A analogues. 127:11234-11235. 2005
Rhodopsin reconstituted into a planar-supported lipid bilayer retains photoactivity after cross-linking polymerization of lipid monomers. 127:5320-5321. 2005
Tryptophan side chain electrostatic interactions determine edge-to-face vs parallel-displaced tryptophan side chain geometries in the designed β-hairpin "trpzip2". 127:4668-4674. 2005
(4,2)D projection-reconstruction experiments for protein backbone assignment: application to human carbonic anhydrase II and calbindin D(28K). 127:8785-8795. 2005
A deep cavitand provides a structured environment for the menschutkin reaction. 127:11222-11223. 2005
A designed synthetic analogue of 4-OT is specific for a non-natural substrate. 127:5862-5868. 2005
A dimerization "switch" in the internalization mechanism of a cell-penetrating peptide. 127:538-539. 2005
A pentenyl dianion-based strategy for convergent synthesis of ene-1,5-diols. 127:3694-3695. 2005
A potent transactivation domain mimic with activity in living cells. 127:8254-8255. 2005
A tandem orthogonal proteolysis strategy for high-content chemical proteomics. 127:10018-10019. 2005
Active site structure of class I ribonucleotide reductase intermediate X: a density functional theory analysis of structure, energetics, and spectroscopy. 127:15778-15790. 2005
Antibody-catalyzed asymmetric intramolecular michael addition of aldehydes and ketones to yield the disfavored cis-product. 127:13104-13105. 2005
Biosynthesis of the beta-amino acid moiety of the enediyne antitumor antibiotic c-1027 featuring beta-amino acyl-s-carrier protein intermediates. 127:11594-11595. 2005
CH activation with an O-donor iridium-methoxo complex. 127:14172-14173. 2005
Cloning, sequencing, analysis, and heterologous expression of the fredericamycin biosynthetic gene cluster from streptomyces griseus. 127:16442-16452. 2005
Controlling the morphology of cross beta-sheet assemblies by rational design. 127:8562-8570. 2005
Copper(I)-catalyzed synthesis of azoles. DFT study predicts unprecedented reactivity and intermediates. 127:210-216. 2005
Cysteine-derived organocatalyst in a highly enantioselective intramolecular Michael reaction. 127:16028-16029. 2005
Cysteine-derived organocatalyst in a highly enantioselective intramolecular michael reaction. 127:16028-16029. 2005
Decomposition of triacetone triperoxide is an entropic explosion. 127:1146-1159. 2005
Deep cavitands provide organized solvation of reactions. 127:11904-11905. 2005
Differential solvation and tautomer stability of a model base pair within the minor and major grooves of DNA. 127:15612-15617. 2005
Discovery of a biologically active thiostrepton fragment. 127:15042-15044. 2005
E-olefin dipeptide isostere incorporation into a polypeptide backbone enables hydrogen bond perturbation: probing the requirements for Alzheimer's amyloidogenesis. 127:15366-15367. 2005
Elucidation of fatty acid amide hydrolase inhibition by potent alpha-ketoheterocycle derivatives from Monte Carlo simulations. 127:17377-17384. 2005
Enantioselective total syntheses of welwitindolinone A and fischerindoles I and G. 127:15394-15396. 2005
Experimental evidence for chair-like transition states in aldol reactions of methyl ketone lithium enolates: stereoselective synthesis and utilization of a deuterium-labeled enolate as a probe of reaction stereochemistry. 127:5770-5771. 2005
Fluorescent cocaine probes: A tool for the selection and engineering of therapeutic antibodies. 127:2477-2484. 2005
In situ selection of lead compounds by click chemistry: Target-guided optimization of acetylcholinesterase inhibitors. 127:6686-6692. 2005
Iso-migrastatin congeners from streptomyces platensis and generation of a glutarimide polyketide library featuring the dorrigocin, lactimidomycin, migrastatin, and nk30424 scaffolds. 127:11930-11931. 2005
Kinetic stabilization of an oligomeric protein by a single ligand binding event. 127:5540-5551. 2005
Luminescent ruthenium(II)- and rhenium(I)-diimine wires bind nitric oxide synthase. 127:5169-5173. 2005
Migrastatin and dorrigocins are shunt metabolites of iso-migrastatin. 127:1622-1623. 2005
O-GlcNAcase catalyzes cleavage of thioglycosides without general acid catalysis. 127:17202-17203. 2005
Origin of selectivity in the antibody 20f10-catalyzed yang cyclization. 127:132-145. 2005
Parallel biomolecular computation on surfaces with advanced finite automata. 127:3935-3943. 2005
Polymerase evolution: Efforts toward expansion of the genetic code. 127:12470-12471. 2005
Potent and selective structure-based dibenzofuran inhibitors of transthyretin amyloidogenesis: Kinetic stabilization of the native state. 127:6662-6671. 2005
Redox couples of inducible nitric oxide synthase. 127:11212-11213. 2005
Remarkable phosphine-effect on the intramolecular aldol reactions of unsaturated 1,5-diketones: highly regioselective synthesis of cross-conjugated dienones. 127:16778-16779. 2005
Ruthenium-catalyzed cycloaddition of alkynes and organic azides. 127:15998-15999. 2005
Structural characterization of a p-acetylphenylalanyl aminoacyl-tRNA synthetase. 127:14976-14977. 2005
Synthesis, structure, and reactivity of O-donor Ir(III) complexes: C-H activation studies with benzene. 127:11372-11389. 2005
The allylic azide rearrangement: achieving selectivity. 127:13444-13445. 2005
The role of chelating diamine ligands in the goldberg reaction: a kinetic study on the copper-catalyzed amidation of aryl iodides. 127:4120-4121. 2005
The total synthesis of coleophomones B, C, and D. 127:8872-8888. 2005
Total synthesis of (+)-13-deoxytedanolide. 127:6186-6187. 2005
Total synthesis of asimicin via highly stereoselective [3 + 2] annulation reactions of substituted allylsilanes. 127:10818-10819. 2005
Total synthesis of ningalin D. 127:10767-10770. 2005
Total synthesis of piericidin A1 and B1. 127:15704-15705. 2005
Total synthesis of thiostrepton. Assembly of key building blocks and completion of the synthesis. 127:11176-11183. 2005
Total synthesis of thiostrepton. Retrosynthetic analysis and construction of key building blocks. 127:11159-11175. 2005
Toward cocaine esterase therapeutics. 127:10016-10017. 2005
Tuning the enantioselective N-acetylation of racemic amines: A spectacular salt effect. 127:6138-6139. 2005
Virus crystals as nanocomposite scaffolds. 127:5274-5275. 2005
Why are BINOL-based monophosphites such efficient ligands in Rh-catalyzed asymmetric olefin hydrogenation?. 127:10305-10313. 2005
Designing sequence to control protein function in an EF-hand protein. 126:5990-5998. 2004
Electron transfer between cytochrome c and cytochome c peroxidase in single crystals. 126:10836-10837. 2004
Enantioselective formal hydration of α,β-unsaturated imides by Al-catalyzed conjugate addition of oxime nucleophiles. 126:14724-14725. 2004
Metal-assisted assembly and stabilization of collagen-like triple helices. 126:15030-15031. 2004
NMR structure of a cyclic polyamide-DNA complex. 126:7958-7966. 2004
Nonspecific medium effects versus specific group positioning in the antibody and albumin catalysis of the base-promoted ring-opening reactions of benzisoxazoles. 126:8197-8205. 2004
Oligothiophene isocyanides for platinum-based molecular electronic applications. 126:11796-11797. 2004
Palladium-catalyzed synthesis of N-aryl-2-benzylindolines via tandem arylation of 2-allylaniline: control of selectivity through in situ catalyst modification. 126:13906-13907. 2004
Precursor-directed biosynthesis of epothilone in Escherichia coli. 126:7436-7437. 2004
Structural mining: self-consistent design on flexible protein-peptide docking and transferable binding affinity potential. 126:8515-8528. 2004
The effect of mutation on RNA Diels-Alderases. 126:11843-11851. 2004
A catalysis-based selection for peroxidase antibodies with increased activity. 126:3006-3007. 2004
A functionalized, deep cavitand catalyzes the aminolysis of a choline derivative. 126:7424-7425. 2004
A genetically encoded photocaged amino acid. 126:14306-14307. 2004
A high-resolution probe of protein folding. 126:3384-3385. 2004
A new method for the stereoselective synthesis of α- and β-glycosylamines using the burgess reagent. 126:6234-6235. 2004
A phage display system with unnatural amino acids. 126:15962-15963. 2004
A powerful selection assay for mixture libraries of DNA alkylating agents. 126:9194-9195. 2004
A precipitator for the detection of thiophilic metals in aqua. 126:16582-16586. 2004
Antisymmetric exchange in 2fe-2s (1+) clusters: Epr of the rieske protein from thermus thermophilus at ph 14. 126:5338-5339. 2004
Biomimetically inspired total synthesis and structure activity relationships of 1-o-methyllateriflorone. 6 pi electrocyclizations in organic synthesis. 126:5493-5501. 2004
Boolean logic functions of a synthetic peptide network. 126:11140-11141. 2004
Calculating the electron paramagnetic resonance parameters of exchange coupled transition metal complexes using broken symmetry density functional theory: application to a MnIII/MnIV model compound. 126:2613-2622. 2004
Catalysis by a synthetic receptor sealed at one end and functionalized at the other. 126:16280-16281. 2004
Chemistry and biology of diazonamide A: First total synthesis and confirmation of the true structure. 126:12888-12896. 2004
Chemistry and biology of diazonamide A: Second total synthesis and biological investigations. 126:12897-12906. 2004
Covalent display of oligosaccharide arrays in microtiter plates. 126:8640-8641. 2004
Cyclic amidine sugars as transition-state analogue inhibitors of glycosidases: Potent competitive inhibitors of mannosidases. 126:1971-1979. 2004
Dedifferentiation of lineage-committed cells by a small molecule. 126:410-411. 2004
Design and use of fluorogenic aldehydes for monitoring the progress of aldehyde transformations. 126:3692-3693. 2004
Detection of bacteria with carbohydrate-functionalized fluorescent polymers. 126:13343-13346. 2004
Development of a functionalized xenon biosensor. 126:15287-15294. 2004
Direct coupling of indoles with carbonyl compounds: Short, enantioselective, gram-scale synthetic entry into the hapalindole and fischerindole alkaloid families. 126:7450-7451. 2004
Discovery and characterization of catalysts for azide-alkyne cycloaddition by fluorescence quenching. 126:9152-9153. 2004
Dissecting ramoplanin: mechanistic analysis of synthetic ramoplanin analogues as a guide to the design of improved antibiotics. 126:7462-7463. 2004
Effects of lipid chain lengths in alpha-galactosylceramides on cytokine release by natural killer T cells. 126:13602-13603. 2004
Efforts to expand the genetic alphabet: Identification of a replicable unnatural DNA self-pair. 126:6923-6931. 2004
Electrostatic interactions dominate the catalytic contribution of Arg39 in 4-oxalocrotonate tautomerase. 126:12726-12727. 2004
Enzymatic synthesis and 19F NMR studies of 2-fluoroadenine-substituted RNA. 126:11776-11777. 2004
Equilibrium isotope effects as a probe of nonbonding attractions. 126:11428-11429. 2004
Establishing the parabolic relationship between reactivity and activity for derivatives and analogues of the duocarmycin and CC-1065 alkylation subunits. 126:80-81. 2004
Evidence for a post-translational modification, aspartyl aldehyde, in a photosynthetic membrane protein. 126:8399-8405. 2004
Expanding the substrate repertoire of a DNA polymerase by directed evolution. 126:1748-1754. 2004
Helical folding of alkanes in a self-assembled, cylindrical capsule. 126:13512-13518. 2004
Heterocyclic peptide backbone modifications in an α-helical coiled coil. 126:15366-15367. 2004
Hydrogen-bonded encapsulation complexes in protic solvents. 126:14149-14156. 2004
Immunological consequences of methamphetamine protein glycation. 126:11446-11447. 2004
In situ catalyst improvement in the proline-mediated alpha-amination of aldehydes. 126:11770-11771. 2004
In situ click chemistry: Enzyme inhibitors made to their own specifications. 126:12809-12818. 2004
Inhibition of the proteolytic activity of anthrax lethal factor by aminoglycosides. 126:4774-4775. 2004
Isotopomer encapsulation in a cylindrical molecular capsule: A probe for understanding noncovalent isotope effects on a molecular level. 126:7738-7739. 2004
Kinetically stable complexes in water: The role of hydration and hydrophobicity. 126:2870-2876. 2004
Kinetics and thermodynamics of hexameric capsule formation. 126:2939-2943. 2004
Mapping enzyme active sites in complex proteomes. 126:1363-1368. 2004
Mechanically regulated rotation of a guest in a nanoscale host. 126:12728-12729. 2004
Mechanism of homogeneous Ir(III) catalyzed regioselective arylation of olefins. 126:352-363. 2004
Mechanistic analysis of hydroarylation catalysts. 126:11658-11665. 2004
Mechanistic investigation leads to a synthetic improvement in the hydrolytic kinetic resolution of terminal epoxides. 126:1360-1362. 2004
Microarray platform for profiling enzyme activities in complex proteomes. 126:15640-15641. 2004
On the role of the conserved aspartate in the hydrolysis of the phosphocysteine intermediate of the low molecular weight tyrosine phosphatase. 126:12677-12684. 2004
Optimization of interstrand hydrophobic packing interactions within unnatural DNA base pairs. 126:14419-14427. 2004
Periodate-triggered cross-linking of dopa-containing peptide-protein complexes. 126:11442-11443. 2004
Photolithographic synthesis of peptoids. 126:4088-4089. 2004
Porphyrin distortion during affinity maturation of a ferrochelatase antibody, monitored by resonance Raman spectroscopy. 126:16361-16367. 2004
Probing the active catalyst in product-accelerated proline-mediated reactions. 126:16312-16313. 2004
Selective derivatization and sequestration of ribose from a prebiotic mix. 126:9578-9583. 2004
Short total synthesis of (+/-)-sceptrin. 126:3726-3727. 2004
Single molecule solvation and its effects on tautomeric equilibria in a self-assembled capsule. 126:8956-8960. 2004
Small molecules that induce cardiomyogenesis in embryonic stem cells. 126:1590-1591. 2004
Steric and magnetic asymmetry distinguished by encapsulation. 126:6216-6217. 2004
Studies toward diazonamide A: Development of a hetero-pinacol macrocyclization cascade for the construction of the bis-macrocyclic framework of the originally proposed structure. 126:10174-10182. 2004
Studies toward diazonamide A: Initial synthetic forays directed toward the originally proposed structure. 126:10162-10173. 2004
Total synthesis and examination of three key analogues of ramoplanin: a lipoglycodepsipeptide with potent antibiotic activity. 126:1041-1043. 2004
Total synthesis of formamicin. 126:9307-9317. 2004
Total synthesis of hamigerans and analogues thereof. Photochemical generation and diels-alder trapping of hydroxy-o-quinodimethanes. 126:613-627. 2004
Total synthesis of hybocarpone and analogues thereof. A facile dimerization of naphthazarins to pentacyclic systems. 126:607-612. 2004
Total synthesis of the ristocetin aglycon. 126:4310-4317. 2004
Total synthesis, structure revision, and absolute configuration of (+)-yatakemycin. 126:8396-8398. 2004
Toward assessing the position-dependent contributions of backbone hydrogen bonding to β-sheet folding thermodynamics employing amide-to-ester perturbations. 126:16762-16771. 2004
o-Iodoxybenzoic acid (IBX) as a viable reagent in the manipulation of nitrogen- and sulfur-containing substrates: scope, generality, and mechanism of IBX-mediated amine oxidations and dithiane deprotections. 126:5192-5201. 2004
A bifunctional molecule that displays context-dependent cellular activity. 125:7575-7580. 2003
A copper-catalyzed C-N bond formation involving sp-hybridized carbons. A direct entry to chiral ynamides via N-alkynylation of amides. 125:2368-2369. 2003
A selective irreversible inhibitor targeting a PDZ protein interaction domain. 125:12074-12075. 2003
An enantioselective synthesis of FR182877 provides a chemical rationalization of its structure and affords multigram quantities of its direct precursor. 125:5393-5407. 2003
Combined experimental/theoretical refinement of indole ring geometry using deuterium magnetic resonance and ab initio calculations. 125:12268-12276. 2003
Epothilone C macrolactonization and hydrolysis are catalyzed by the isolated thioesterase domain of epothilone polyketide synthase. 125:3428-3429. 2003
Mechanism of the glutathione transferase-catalyzed conversion of antitumor 2-crotonyloxymethyl-2-cycloalkenones to GSH adducts. 125:15049-15058. 2003
Novel selective inhibitors of the interaction of individual nuclear hormone receptors with a mutually shared steroid receptor coactivator 2. 125:6852-6853. 2003
Reversible switching of high-speed air-liquid two-phase flows using electrowetting-assisted flow-pattern change. 125:14678-14679. 2003
Self-assembly combining two bioactive peptide-amphiphile molecules into nanofibers by electrostatic attraction. 125:7146-7147. 2003
Spectroscopy and reactivity of a photogenerated tryptophan radical in a structurally defined protein environment. 125:14220-14221. 2003
Synthesis and activity of ruthenium alkylidene complexes coordinated with phosphine and N-heterocyclic carbene ligands. 125:2546-2558. 2003
Theoretical calculations of carbon-oxygen bond dissociation enthalpies of peroxyl radicals formed in the autoxidation of lipids. 125:5801-5810. 2003
Understanding the mechanism of H(+)-induced demetalation as a design strategy for robust iron(III) peroxide-activating catalysts. 125:12378-12379. 2003
A heterocyclic peptide nanotube. 125:9372-9376. 2003
A method for the generation of glycoprotein mimetics. 125:1702-1703. 2003
A mild, catalytic, and highly selective method for the oxidation of alpha,beta-enones to 1,4-enediones. 125:3232-3233. 2003
A new strategy for improved nicotine vaccines using conformationally constrained haptens. 125:7164-7165. 2003
A novel 4-methylideneimidazole-5-one-containing tyrosine aminomutase in enediyne antitumor antibiotic c-1027 biosynthesis. 125:6062-6063. 2003
A potent and highly selective inhibitor of human α-1,3-fucosyltransferase via click chemistry. 125:9588-9589. 2003
Activity-based protein profiling in vivo using a copper(i)-catalyzed azide-alkyne 3+2 cycloaddition. 125:4686-4687. 2003
Adding amino acids with novel reactivity to the genetic code of Saccharomyces cerevisiae. 125:11782-11783. 2003
Adsorption of beta-hairpin peptides on the surface of water: A neutron reflection study. 125:3751-3757. 2003
Alkane C-H activation and catalysis by an O-donor ligated iridium complex. 125:14292-14293. 2003
Application of NMR SHAPES screening to an RNA target. 125:15724-15725. 2003
Assembly of resorcinarene capsules in wet solvents. 125:3432-3433. 2003
Asymmetric environments in encapsulation complexes. 125:6239-6243. 2003
Bioconjugation by copper(I)-catalyzed azide-alkyne [3 + 2] cycloaddition. 125:3192-3193. 2003
Catalysis of the photo-Fries reaction: Antibody-mediated stabilization of high energy states. 125:15395-15401. 2003
DNA alkylation properties of yatakemycin. 125:10971-10976. 2003
DNA detection and signal amplification via an engineered allosteric enzyme. 125:344-345. 2003
DNA-based photonic logic gates: AND, NAND, and INHIBIT. 125:346-347. 2003
Density functional and reduction potential calculations of Fe4S4 clusters. 125:1923-1936. 2003
Determinants of unnatural nucleobase stability and polymerase recognition. 125:9638-9646. 2003
Experimental determination of the absolute enantioselectivity of an anti body-catalyzed Diels-Alder reaction and theoretical explorations of the origins of stereoselectivity. 125:2489-2506. 2003
Fabrication of assembled virus nanostructures on templates of chemoselective linkers formed by scanning probe nanolithography. 125:6848-6849. 2003
Fluorescent detection of carbon-carbon bond formation. 125:8523-8528. 2003
Fundamental role of the fostriecin unsaturated lactone and implications for selective protein phosphatase inhibition. 125:15694-15695. 2003
Generation of a bacterium with a 21 amino acid genetic code. 125:935-939. 2003
Hybridization-based unquenching of DNA hairpins on au surfaces: prototypical "molecular beacon" biosensors. 125:4012-4013. 2003
Individual solvent/solute interactions through social isomerism. 125:13981-13983. 2003
Insights into the origin of high activity and stability of catalysts derived from bulky, electron-rich monophosphinobiaryl ligands in the Pd-catalyzed C-N bond formation. 125:13978-13980. 2003
Isolation of protein ligands from large peptoid libraries. 125:13995-14004. 2003
Kinetic evidence for a tetrameric transition state in the asymmetric autocatalytic alkylation of pyrimidyl aldehydes. 125:8978-8979. 2003
Mixed-element capture agents: A simple strategy for the construction of synthetic, high-affinity protein capture ligands. 125:9550-9551. 2003
Partitioning the loss in vancomycin binding affinity for D-Ala-D-Lac into lost H-bond and repulsive lone pair contributions. 125:9314-9315. 2003
Photoisomerization and proton transfer in photoactive yellow protein. 125:8186-8194. 2003
Reactivity and molecular recognition: Amine methylation by an introverted ester. 125:14682-14683. 2003
Short, enantioselective total synthesis of okaramine n. 125:5628-5629. 2003
Site-specific incorporation of a redox-active amino acid into proteins. 125:14662-14663. 2003
Small-molecule switches for zinc finger transcription factors. 125:612-613. 2003
Structural, spectroscopic, and redox consequences of central ligand in the FeMoco of nitrogenase: a density functional theoretical study. 125:8377-8383. 2003
Structure of antibacterial peptide microcin J25: a 21-residue lariat protoknot. 125:12382-12383. 2003
Symmetry and bonding in metalloporphyrins. A modern implementation for the bonding analyses of five- and six-coordinate high-spin iron(III)-porphyrin complexes through density functional calculation and NMR spectroscopy. 125:6774-6783. 2003
Synthesis and characterization of potent bivalent amyloidosis inhibitors that bind prior to transthyretin tetramerization. 125:13404-13414. 2003
The effect of minor-groove hydrogen-bond acceptors and donors on the stability and replication of four unnatural base pairs. 125:6134-6139. 2003
Theoretical examination of Mg(2+)-mediated hydrolysis of a phosphodiester linkage as proposed for the hammerhead ribozyme. 125:9861-9867. 2003
Total synthesis of apoptolidin: Completion of the synthesis and analogue synthesis and evaluation. 125:15443-15454. 2003
Total synthesis of apoptolidin: Construction of enantiomerically pure fragments. 125:15433-15442. 2003
Total synthesis of the ramoplanin a2 and ramoplanose aglycon. 125:1877-1887. 2003
Why is tetrazole formation by addition of azide to organic nitriles catalyzed by zinc(II) salts?. 125:9983-9987. 2003
A synthesis of (+)-FR182877, featuring tandem transannular Diels-Alder reactions inspired by a postulated biogenesis. 124:4552-4553. 2002
An enzyme library approach to biocatalysis: development of nitrilases for enantioselective production of carboxylic acid derivatives. 124:9024-9025. 2002
Callipeltoside A: total synthesis, assignment of the absolute and relative configuration, and evaluation of synthetic analogues. 124:10396-10415. 2002
Contribution of aromatic interactions to alpha-helix stability. 124:9751-9755. 2002
Design of three-dimensional, millimeter-scale models for molecular folding. 124:18-19. 2002
Membraneless vanadium redox fuel cell using laminar flow. 124:12930-12931. 2002
Ruthenium-mediated cycloaromatization of acyclic enediynes and dienynes at ambient temperature. 124:3506-3507. 2002
Template-directed self-assembly of 10-mu m-sized hexagonal plates. 124:5419-5426. 2002
A combinatorial scaffold approach toward kinase-directed heterocycle libraries. 124:1594-1596. 2002
A highly enantioselective amino acid-catalyzed route to functionalized alpha-amino acids. 124:1842-1843. 2002
A highly enantioselective route to either enantiomer of both alpha- and beta-amino acid derivatives. 124:1866-1867. 2002
A modular assembly strategy for improving the substrate specificity of small catalytic peptides. 124:3510-3511. 2002
A novel silver(I)-mediated DNA base pair. 124:13684-13685. 2002
A parallel approach to the discovery of carrier delivery vehicles to enhance antigen immunogenicity. 124:4946-4947. 2002
A potent and highly selective sulfotransferase inhibitor. 124:14524-14525. 2002
A short synthetic route to (+)-austamide, (+)-deoxyisoaustamide, and (+)-hydratoaustamide from a common precursor by a novel palladium-mediated indole -> dihydroindoloazocine cyclization. 124:7904-7905. 2002
A small molecule with osteogenesis-inducing activity in multipotent mesenchymal progenitor cells. 124:14520-14521. 2002
A structural model for the high-valent intermediate Q of methane monooxygenase from broken-symmetry density functional and electrostatics calculations. 124:5890-5894. 2002
A synthetic receptor for choline and carnitine. 124:14014-14016. 2002
Adding L-3-(2-naphthyl)alanine to the genetic code of E. coli. 124:1836-1837. 2002
Addition of p-azido-L-phenylaianine to the genetic code of Escherichia coli. 124:9026-9027. 2002
An NMR study of the rates of single-molecule exchange in a cylindrical host capsule. 124:8780-8781. 2002
Aqueous aldol catalysis by a nicotine metabolite. 124:3220-3221. 2002
Atropselective macrocyclization of diaryl ether ring systems: Application to the synthesis of vancomycin model systems. 124:10451-10455. 2002
Binding modes for the first coupled electron and proton addition to FeMoco of nitrogenase. 124:4546-4547. 2002
Cell-wall engineering of living bacteria. 124:9018-9019. 2002
Crystal structure of a B-form DNA duplex containing (L)-alpha-threofuranosyl (3 '-> 2 ') nucleosides: A four-carbon sugar is easily accommodated into the backbone of DNA. 124:13716-13721. 2002
Density functional study of the mechanism of a tyrosine phosphatase: I. Intermediate formation. 124:10225-10235. 2002
Efficient chemoenzymatic synthesis of o-linked sialyl oligosaccharides. 124:5739-5746. 2002
Enantioselective synthesis of 1,5-anti- and 1,5-syn-diols using a highly diastereoselective one-pot double allylboration reaction sequence. 124:13644-13645. 2002
Enzymatic phosphorylation of unnatural nucleosides. 124:14626-14630. 2002
Erythropoietin mimetics derived from solution phase combinatorial libraries. 124:544-555. 2002
Extending synthetic access to proteins with a removable acyl transfer auxiliary. 124:4642-4646. 2002
Fluorescent probes for cytochrome p450 structural characterization and inhibitor screening. 124:10254-10255. 2002
Hairpin versus extended DNA binding of a substituted beta-alanine linked polyamide. 124:2148-2152. 2002
Intramolecular Diels-Alder and tandem intramolecular Diels-Alder/1,3-dipolar cycloaddition reactions of 1,3,4-oxadiazoles. 124:11292-11294. 2002
Iodine(V) reagents in organic synthesis. Part 1. Synthesis of polycyclic heterocycles via Dess-Martin periodinane-mediated cascade cyclization: Generality, scope, and mechanism of the reaction. 124:2212-2220. 2002
Iodine(V) reagents in organic synthesis. Part 2. Access to complex molecular architectures via Dess-Martin periodinane-generated o-imidoquinones. 124:2221-2232. 2002
Iodine(V) reagents in organic synthesis. Part 3. New routes to heterocyclic compounds via o-iodoxybenzoic acid-mediated cyclizations: Generality, scope, and mechanism. 124:2233-2244. 2002
Iodine(V) reagents in organic synthesis. Part 4. O-iodoxybenzoic acid as a chemospecific tool for single electron transfer-based oxidation processes. 124:2245-2258. 2002
Magnetic resonance imaging detects a specific peptide-protein binding event. 124:3514-3515. 2002
Mechanisms of tetrazole formation by addition of azide to nitriles. 124:12210-12216. 2002
Mechanistic insights into the Pd(BINAP)-catalyzed amination of aryl bromides: kinetic studies under synthetically relevant conditions. 124:14104-14114. 2002
Metal-switching and self-inclusion of functional cavitands. 124:10349-10358. 2002
Modulating ion channel properties of transmembrane peptide nanotubes through heteromeric supramolecular assemblies. 124:10004-10005. 2002
Novel chemistry of alpha-tosyloxy ketones: Applications to the solution- and solid-phase synthesis of privileged heterocycle and enediyne libraries. 124:5718-5728. 2002
Phage-display selection of a human single-chain fv antibody highly specific for melanoma and breast cancer cells using a chemoenzymatically synthesized G(M3)-carbohydrate antigen. 124:12439-12446. 2002
Protein dynamics and cytochrome c: Correlations between ligand vibrations and redox activity. 124:1846-1847. 2002
RNA-cleaving DNA enzymes with altered regio- or enantioselectivity. 124:12499-12506. 2002
Rationalization of anomalous nonlinear effects in the alkylation of substituted benzaldehydes. 124:13652-13653. 2002
Social isomers in encapsulation complexes. 124:12074-12075. 2002
Solid-phase synthesis of oligosaccharides and on-resin quantitative monitoring using gated decoupling c-13 NMR. 124:3591-3599. 2002
Solution NMR techniques for large molecular and supramolecular structures. 124:12144-12153. 2002
Solution-phase parallel synthesis of a pharmacophore library of hun-7293 analogues: a general chemical mutagenesis approach to defining structure-function properties of naturally occurring cyclic (depsi)peptides. 124:5431-5440. 2002
Stability and selectivity of unnatural DNA with five-membered-ring nucleobase analogues. 124:1222-1226. 2002
Structural chemistry of a green fluorescent protein zn biosensor. 124:3522-3524. 2002
Synthesis and DNA binding properties of iminodiacetic acid-linked polyamides: characterization of cooperative extended 2 : 1 side-by-side parallel binding. 124:10676-10682. 2002
Synthesis of a negatively charged dibenzofuran-based beta-turn mimetic and its incorporation into the WW miniprotein-enhanced solubility without a loss of thermodynamic stability. 124:11900-11907. 2002
Synthesis of sugar arrays in microtiter plate. 124:14397-14402. 2002
Synthesis, properties, and reactivity of cocaine benzoylthio ester possessing the cocaine absolute configuration. 124:3661-3668. 2002
The chemistry of amine-azide interconversion: Catalytic diazotransfer and regioselective azide reduction. 124:10773-10778. 2002
The effect of backbone cyclization on the thermodynamics of beta-sheet unfolding: Stability optimization of the PINWW domain. 124:4980-4986. 2002
The origin of diastereofacial control in allylboration reactions using tartrate ester derived allylboronates: attractive interactions between the Lewis acid coordinated aldehyde carbonyl group and an ester carbonyl oxygen. 124:10692-10697. 2002
The synthesis and biological characterization of a ceramide library. 124:1856-1857. 2002
The vinylogous intramolecular Morita-Baylis-Hillman reaction: synthesis of functionalized cyclopentenes and cyclohexenes with trialkylphosphines as nucleophilic catalysts. 124:2404-2405. 2002
Total synthesis of (-)-bafilomycin A(1). 124:6981-6990. 2002
Total synthesis of the CP-molecules (CP-263,114 and CP-225,917, phomoidrides B and A). 1. Racemic and asymmetric synthesis of bicyclo 4.3.1 key building blocks. 124:2183-2189. 2002
Total synthesis of the CP-molecules (CP-263,114 and CP-225,917, phomoidrides B and A). 2. Model studies for the construction of key structural elements and first-generation strategy. 124:2190-2201. 2002
Total synthesis of the CP-molecules (CP-263,114 and CP-225,917, phomoidrides B and A). 3. Completion and synthesis of advanced analogues. 124:2202-2211. 2002
Total synthesis of the ramoplanin a2 and ramoplanose aglycon. 124:5288-5290. 2002
Toward synthetic transcription activators: Recruitment of transcription factors to DNA by a pna-peptide chimera. 124:1838-1839. 2002
Tppt(iv)me(h)(2) forms a sigma-ch4 complex that is kinetically resistant to methane liberation. 124:3226-3228. 2002
Tpptme(h)(2): Why is there h/d scrambling of the methyl group but not methane loss?. 124:7041-7054. 2002
Water-stabilized cavitands. 124:2854-2855. 2002
An inhibitor of the interaction of thyroid hormone receptor beta and glucocorticoid interacting protein 1. 123:1525-1526. 2001
Chromatographic purification of soluble single-walled carbon nanotubes (s-SWNTs). 123:733-734. 2001
Concise asymmetric syntheses of radicicol and monocillin I. 123:10903-10908. 2001
Conformational analysis of a flexible oligosaccharide using residual dipolar couplings. 123:485-492. 2001
Electron tunneling in single crystals of Pseudomonas aeruginosa azurins. 123:11623-11631. 2001
Properties of photogenerated tryptophan and tyrosyl radicals in structurally characterized proteins containing rhenium(I) tricarbonyl diimines. 123:3181-3182. 2001
Self-assembly of 10-mu m-sized objects into ordered three-dimensional arrays. 123:7677-7682. 2001
Substrate recognition and selection by the initiation module PheATE of gramicidin S synthetase. 123:11208-11218. 2001
Three-dimensional self-assembly of complex, millimeter-scale structures through capillary bonding. 123:8119-8120. 2001
Total synthesis of deschlorocallipeltoside A. 123:9449-9450. 2001
"Flexiball" toolkit: A modular approach to self-assembling capsules. 123:11519-11533. 2001
A de novo designed peptide ligase: A mechanistic investigation. 123:1797-1803. 2001
A self-folding metallocavitand. 123:9929-9934. 2001
A simple, high-resolution method for establishing DNA binding affinity and sequence selectivity. 123:5878-5891. 2001
Amino acid catalyzed direct asymmetric aldol reactions: A bioorganic approach to catalytic asymmetric carbon-carbon bond-forming reactions. 123:5260-5267. 2001
An efficient chemoenzymatic strategy for the synthesis of wild-type and vancomycin-resistant bacterial cell-wall precursors: UDP-N-acetylmuramyl-peptides. 123:9916-9917. 2001
Asymmetric total synthesis of ent-(-)-roseophilin: Assignment of absolute configuration. 123:8515-8519. 2001
C-13,c-13 - and c-13,h-1 -trosy in a triple resonance experiment for ribose-base and intrabase correlations in nucleic acids. 123:658-664. 2001
Cavitand-porphyrins. 123:4659-4669. 2001
Chemical synthesis and biological evaluation of cis- and trans-12,13-cyclopropyl and 12,13-cyclobutyl epothilones and related pyridine side chain analogues. 123:9313-9323. 2001
Chiral softballs: Synthesis and molecular recognition properties. 123:5213-5220. 2001
Cloning and heterologous expression of the macrotetrolide biosynthetic gene cluster revealed a novel polyketide synthase that lacks an acyl carrier protein. 123:3385-3386. 2001
Complete thermodynamic characterization of reduction and protonation of the bc(1)-type rieske 2fe-2s center of thermus thermophilus. 123:9906-9907. 2001
Conversion of enediynes into quinones by antibody catalysis and in aqueous buffers: Implications for an alternative enediynes therapeutic mechanism. 123:3607-3608. 2001
Design of allele-specific protein methyltransferase inhibitors. 123:11608-11613. 2001
Direct observation of protein vibrations by selective incorporation of spectroscopically observable carbon-deuterium bonds in cytochrome c. 123:2426-2427. 2001
Efforts toward expansion of the genetic alphabet: replication of DNA with three base pairs. 123:7439-7440. 2001
FeMo cofactor of nitrogenase: a density functional study of states M(N), M(OX), M(R), and M(I). 123:12392-12410. 2001
First and second generation total synthesis of the teicoplanin aglycon. 123:1862-1871. 2001
High-temperature protein mass mapping using a thermophilic protease. 123:1774-1775. 2001
Identification of a novel class of small-molecule antiangiogenic agents through the screening of combinatorial libraries which function by inhibiting the binding and localization of proteinase MMP2 to integrin alpha(V)beta(3). 123:1280-1288. 2001
Incorporating beta-turns and a turn mimetic out of context in loop 1 of the WW domain affords cooperatively folded beta-sheets. 123:5206-5212. 2001
Kinetic resolution using enantioimpure catalysts: mechanistic considerations of complex rate laws. 123:545-553. 2001
Kinetic studies of heck coupling reactions using palladacycle catalysts: Experimental and kinetic modeling of the role of dimer species. 123:1848-1855. 2001
Medium-dependent self-assembly of an amphiphilic peptide: Direct observation of peptide phase domains at the air-water interface. 123:775-776. 2001
Metal cation complexation and activation of reversed CPyi analogues of CC-1065 and duocarmycin SA: Partitioning the effects of binding and catalysis. 123:9299-9306. 2001
Microbial glycosyltransferases for carbohydrate synthesis: Alpha-2,3-sialyltransferase from neisseria gonorrheae. 123:10909-10918. 2001
Modulating artificial membrane morphology: Ph-induced chromatic transition and nanostructural transformation of a bolaamphiphilic conjugated polymer from blue helical ribbons to red nanofibers. 123:3205-3213. 2001
Monitoring the conformational fluctuations of DNA hairpins using single-pair fluorescence resonance energy transfer. 123:4295-4303. 2001
Observation of unusual kinetics in Heck reactions of aryl halides: the role of non-steady-state catalyst concentration. 123:4621-4622. 2001
Origins of asymmetric amplification in autocatalytic alkylzinc additions. 123:10103-10104. 2001
Residual dipolar coupling TOCSY for direct through space correlations of base protons and phosphorus nuclei in RNA. 123:3395-3396. 2001
Selective oxidation at carbon adjacent to aromatic systems with IBX. 123:3183-3185. 2001
Sequence-dependent correction of random coil NMR chemical shifts. 123:2970-2978. 2001
Structure of a copper-mediated base pair in DNA. 123:12364-12367. 2001
Synthesis and catalytic antibody functionalization of dendrimers. 123:8248-8259. 2001
Synthesis of peptides and proteins without cysteine residues by native chemical ligation combined with desulfurization. 123:526-533. 2001
Tautomerization dynamics of a model base pair in DNA. 123:4613-4614. 2001
Total syntheses of thiocoraline and be-22179 and assessment of their DNA binding and biological properties. 123:561-568. 2001
Total synthesis of fostriecin (CI-920). 123:4161-4167. 2001
A concise synthesis of (-)-hispidospermidin guided by a postulated biogenesis. 122:9556-9557. 2000
Carbene complexes in the synthesis of complex natural products: total synthesis of the calphostins. 122:3224-3225. 2000
Molecular dynamics simulations of nucleic acids with a generalized born solvation model. 122:2489-2498. 2000
RNA Diels-Alderases: relationships between unique sequences and catalytic function. 122:1015-1021. 2000
Surveying for surfaces that resist the adsorption of proteins. 122:8303-8304. 2000
A highly efficient method for site-specific modification of unprotected peptides after chemical synthesis. 122:3567-3573. 2000
A highly stereoselective synthesis of the landomycin A hexasaccharide unit. 122:6124-6125. 2000
A new functional suppressor tRNA/aminoacyl-tRNA synthetase pair for the in vivo incorporation of unnatural amino acids into proteins. 122:5010-5011. 2000
A new method for the one-step synthesis of alpha,beta-unsaturated carbonyl systems from saturated alcohols and carbonyl compounds. 122:7596-7597. 2000
A new method of in situ activation for a novel class of DNA alkylating agents: tunable metal cation complexation and activation. 122:6325-6326. 2000
A novel copper-mediated DNA base pair. 122:10714-10715. 2000
A novel strategy for the solid-phase synthesis of substituted indolines. 122:2966-2967. 2000
A phototautomerizable model DNA base pair. 122:9917-9920. 2000
Anti-markovnikov olefin arylation catalyzed by an iridium complex. 122:7414-7415. 2000
Antibodies mimic natural oxidosqualene-cyclase action in steroid ring a formation. 122:40-45. 2000
Antibody-catalysis of a bimolecular asymmetric 1,3-dipolar cycloaddition reaction. 122:3244-3245. 2000
Biomimetic total synthesis of bisorbicillinol, bisorbibutenolide, trichodimerol, and designed analogues of the bisorbicillinoids. 122:3071-3079. 2000
Chemically reactive immunogens lead to functional convergence of the immune response. 122:10743-10753. 2000
Chemoenzymatic synthesis of a PSGL-1 N-terminal glycopeptide containing tyrosine sulfate and α-O-linked sialyl Lewis X. 122:4241-4242. 2000
Chiral space in a unimolecular capsule. 122:7811-7812. 2000
Cyclic peptides as molecular adapters for a pore-forming protein. 122:11757-11766. 2000
Design of bifunctional antibiotics that target bacterial rRNA and inhibit resistance-causing enzymes. 122:5230-5231. 2000
Design, synthesis, and characterization of 4-ester CI2, a model for backbone hydrogen bonding in protein α-helices. 122:12079-12082. 2000
Detection and mechanistic studies of multicomponent assembly by fluorescence resonance energy transfer. 122:7876-7882. 2000
Diversity and selection in self-assembled tetrameric capsules. 122:4251-4252. 2000
Efforts toward expansion of the genetic alphabet: optimization of interbase hydrophobic interactions. 122:7621-7632. 2000
Efforts toward the expansion of the genetic alphabet: information storage and replication with unnatural hydrophobic base pairs. 122:3274-3287. 2000
Emergent conformational preferences of a self-assembling small molecule: Structure and dynamics in a tetrameric capsule. 122:10991-10996. 2000
Expanded calix[4]arene tetraurea capsules. 122:9868-9869. 2000
Highly enantioselective palladium(ii)-catalyzed cyclization of (z)-4 '-acetoxy-2 '-butenyl 2-alkynoates: An efficient synthesis of optically active gamma-butyrolactones. 122:7604-7605. 2000
Intein-mediated synthesis of proteins containing carbohydrates and other molecular probes. 122:5421-5428. 2000
Natural product-like combinatorial libraries based on privileged structures. 1. General principles and solid-phase synthesis of benzopyrans. 122:9939-9953. 2000
Natural product-like combinatorial libraries based on privileged structures. 2. Construction of a 10 000-membered benzopyran library by directed split-and-pool chemistry using nanokans and optical encoding. 122:9954-9967. 2000
Natural product-like combinatorial libraries based on privileged structures. 3. The "libraries from libraries" principle for diversity enhancement of benzopyran libraries. 122:9968-9976. 2000
New molecular vessels: Synthesis and chiroselective recognition. 122:9628-9630. 2000
Nmr assignment and secondary structure determination of an octameric 110 kda protein using trosy in triple resonance experiments. 122:7543-7548. 2000
Novel solution- and solid-phase chemistry of α-sulfonated ketones applicable to combinatorial chemistry. 122:10246-10248. 2000
Polymer-supported (Salen)Mn catalysts for asymmetric epoxidation: A comparison between soluble and insoluble matrices. 122:6929-6934. 2000
Proline-catalyzed direct asymmetric aldol reactions. 122:2395-2396. 2000
Protofilaments, filaments, ribbons, and fibrils from peptidomimetic self-assembly: Implications for amyloid fibril formation and materials science. 122:5262-5277. 2000
RNA cleavage by a DNA enzyme with extended chemical functionality. 122:2433-2439. 2000
Rational design of an unnatural base pair with increased kinetic selectivity. 122:8803-8804. 2000
Reconstructing aldolase antibodies to alter their substrate specificity and turnover. 122:4835-4836. 2000
Self-folding cavitands of nanoscale dimensions. 122:8880-8889. 2000
Structural basis for BABIM inhibition of botulinum neurotoxin type B protease. 122:11268-11269. 2000
Structure-based design of N-phenyl phenoxazine transthyretin amyloid fibril inhibitors. 122:2178-2192. 2000
Synthesis and assembly of self-complementary cavitands. 122:4573-4582. 2000
Thermal atropisomerism of teicoplanin aglycon derivatives: Preparation of the P,P,P and M,P,P atropisomers of the teicoplanin aglycon via selective equilibration of the DE ring system. 122:10047-10055. 2000
Titanium and zirconium et2c2b4h4-metal-phosphine complexes: Synthesis, characterization, and ethylene polymerization activity. 122:10573-10580. 2000
Total syntheses of thiocoraline and be-22179: Establishment of relative and absolute stereochemistry. 122:2956-2957. 2000
Total synthesis of distamycin A and 2640 analogues: A solution-phase combinatorial approach to the discovery of new, bioactive DNA binding agents and development of a rapid, high-throughput screen for determining relative DNA binding affinity or DNA binding sequence selectivity. 122:6382-6394. 2000
Total synthesis of the novel immunosuppressant sanglifehrin a. 122:3830-3838. 2000
Total synthesis of the rubrolone aglycon. 122:12169-12173. 2000
Total synthesis of the teicoplanin aglycon. 122:7416-7417. 2000
Tyrosine sulfation on a psgl-1 glycopeptide influences the reactivity of glycosyltransferases responsible for synthesis of the attached o-glycan. 122:742-743. 2000
Affinity and specificity of multiple hydroxypyrrole/pyrrole ring pairings for coded recognition of DNA. 121:260-261. 1999
Characteristics of an RNA Diels-Alderase active site. 121:3614-3617. 1999
Cycle polyamide motif for recognition of the minor groove of DNA. 121:1121-1129. 1999
First synthesis of a bidesmosidic triterpene saponin by a highly efficient procedure. 121:12196-12197. 1999
Printing small molecules as microarrays and detecting protein-ligand interactions en masse. 121:7967-7968. 1999
Proton-transfer polymerization: A new approach to hyperbranched polymers. 121:2313-2314. 1999
Sequence selectivity of 3-hydroxypyrrole/pyrrole ring pairings in the DNA minor groove. 121:11621-11629. 1999
The allyl leaving group approach to tricoordinate silyl, germyl, and stannyl cations. 121:5001-5008. 1999
A catalytic enantioselective route to hydroxy-substituted quaternary carbon centers: Resolution of tertiary aldols with a catalytic antibody. 121:7283-7291. 1999
A highly stereoselective synthesis of 2-deoxy-beta-glycosides using 2-deoxy-2-iodo-glucopyranosyl acetate donors. 121:3541-3542. 1999
A model for hydride transfer in thymidylate synthase based on unnatural amino acid mutagenesis. 121:7965-7966. 1999
Antibody-metalloporphyrin catalytic assembly mimics natural oxidation enzymes. 121:8978-8982. 1999
Binding-induced activation of DNA alkylation by duocarmycin SA: Insights from the structure of an indole derivative-DNA adduct. 121:5645-5652. 1999
C-13 NMR flux ratio analysis of escherichia coli central carbon metabolism in microaerobic bioprocesses. 121:1407-1408. 1999
Catalytically distinct antibodies prepared by the reactive immunization versus transition state analogue hapten manifolds. 121:10461-10467. 1999
Characterization of self-assembling encapsulation complexes in the gas phase and solution. 121:2133-2138. 1999
Chiral microenvironments in self-assembled capsules. 121:10281-10285. 1999
Conformationally assisted protein ligation using C-terminal thioester peptides. 121:6332-6333. 1999
Crystalline cyclic peptide nanotubes at interfaces. 121:1186-1191. 1999
De novo design of protein function: Predictable structure-function relationships in synthetic redox proteins. 121:858-859. 1999
Design and synthesis of new aminoglycoside antibiotics containing neamine as an optimal core structure: Correlation of antibiotic activity with in vitro inhibition of translation. 121:6527-6541. 1999
Development of a new type of protease inhibitors, efficacious against FIV and HIV variants. 121:1145-1155. 1999
Diastereoselective total synthesis of the vancomycin aglycon with ordered atropisomer equilibrations. 121:3226-3227. 1999
Efforts toward expansion of the genetic alphabet: DNA polymerase recognition of a highly stable, self-fairing hydrophobic base. 121:11585-11586. 1999
Encapsulation of ion-molecule complexes: Second-sphere supramolecular chemistry. 121:7455-7456. 1999
Investigating molecular recognition by mass spectrometry: Characterization of calixarene-based self-assembling capsule hosts with charged guests. 121:4568-4579. 1999
Kinetically stable caviplexes in water. 121:11253-11254. 1999
Lipoic acid biosynthesis: Lipa is an iron-sulfur protein. 121:4706-4707. 1999
Nitrogen-halogen intermolecular forces in solution. 121:7973-7974. 1999
Photoinduced protein cross-linking mediated by palladium porphyrins. 121:11896-11897. 1999
Programmable one-pot oligosaccharide synthesis. 121:734-753. 1999
Selection of human metalloantibodies from a combinatorial phage single-chain antibody library. 121:6517-6518. 1999
Selective antibody-catalyzed solvolysis of endo-2-norbornyl mesylate. 121:10227-10228. 1999
Self-assembling peptidomimetic monolayer nucleates oriented CdS nanocrystals. 121:7266-7267. 1999
Self-complementary cavitands. 121:7459-7460. 1999
Signaling of escherichia coli enterotoxin on supramolecular redox bilayer vesicles. 121:6767-6768. 1999
Stereochemical relationships between encapsulated molecules. 121:4928-4929. 1999
Structural dynamics in the guanylate cyclase heme pocket after co photolysis. 121:7397-7400. 1999
Structural study on O-glycopeptides: Glycosylation-induced conformational changes of O-GlcNAc, O-LacNAc, O-Sialyl-LacNAc, and O-Sialyl-Lewis-X peptides of the mucin domain of madcam-1. 121:2409-2417. 1999
Synthesis of the fully functionalized bicyclic core of garsubellin A. 121:4724-4725. 1999
Total syntheses of ningalin A, lamellarin O, lukianol A, and permethyl storniamide A utilizing heterocyclic azadiene Diels-Alder reactions. 121:54-62. 1999
Total synthesis and comparative evaluation of luzopeptin A-C and quinoxapeptin A-C. 121:11375-11383. 1999
Total synthesis of HUN-7293. 121:6197-6205. 1999
Total synthesis of luzopeptins A-C. 121:1098-1099. 1999
Total synthesis of olivomycin A. 121:1990-1991. 1999
Total synthesis of phomazarin. 121:2471-2477. 1999
Total synthesis of the vancomycin aglycon. 121:10004-10011. 1999
Transfer of chiral information through molecular assembly. 121:11156-11163. 1999
Trosy-type triple-resonance experiments for sequential NMR assignments of large proteins. 121:844-848. 1999
Aliphatic/aromatic amino acid pairings for polyamide recognition in the minor groove of DNA. 120:6219-6226. 1998
Bispheric coordinative structuring in a zinc finger protein: NMR analysis of a point mutant of the carboxy terminal LIM domain of quail cysteine and glycine rich protein CRP2. 120:7127-7128. 1998
Synthesis of the first 2',6 bridged penams. 120:6846-6847. 1998
"Deep-cavity" resorcinarenes dimerize through hydrogen bonding and self-inclusion. 120:4977-4981. 1998
A library approach to the discovery of small molecules that recognize rna: Use of a 1,3-hydroxyamine motif as core. 120:8319-8327. 1998
A light-activated antibody catalyst. 120:12783-12790. 1998
A synthetic retrotransition (backward reading) sequence of the right-handed three-helix bundle domain (10-53) of protein a shows similarity in conformation as predicted by computation. 120:13042-13045. 1998
A systematic evaluation of the bleomycin A(2) L-threonine side chain: its role in preorganization of a compact conformation implicated in sequence-selective DNA cleavage. 120:9139-9148. 1998
Aldolase antibodies of remarkable scope. 120:2768-2779. 1998
Analysis of the role of the active site tyrosine in human glutathione transferase A1-1 by unnatural amino acid mutagenesis. 120:451-452. 1998
Assembly of oligosaccharide libraries with a designed building block and an efficient orthogonal protection-deprotection strategy. 120:7137-7138. 1998
Assessment of the role of the bleomycin A(2) pyrimidoblamic acid C4 amino group. 120:53-65. 1998
Bromine-catalyzed aziridination of olefins. A rare example of atom-transfer redox catalysis by a main group element. 120:6844-6845. 1998
Chiral capsules. 1. Softballs with asymmetric surfaces bind camphor derivatives. 120:66-69. 1998
Cofactor-induced refinement of catalytic antibody activity: A metal-specific allosteric effect. 120:2963-2964. 1998
Convergent functional groups: Intramolecular acyl transfer through a 34-membered ring. 120:5120-5121. 1998
Critical role of the linking amide in CC-1065 and the duocarmycins: implications on the source of DNA alkylation catalysis. 120:11554-11557. 1998
Cylindrical beta-sheet peptide assemblies. 120:8949-8962. 1998
Definition of the effect and role of the bleomycin A(2) valerate substituents: preorganization of a rigid, compact conformation implicated in sequence-selective DNA cleavage. 120:9149-9158. 1998
Diels-Alder reactions through reversible encapsulation. 120:3650-3656. 1998
Direct selection for catalysis from combinatorial antibody libraries using a boronic acid probe: Primary amide bond hydrolysis. 120:2211-2217. 1998
Dynamics of assembly and guest exchange in the tennis ball. 120:6193-6194. 1998
Enantioselective total synthesis of (-)-chlorothricolide via the tandem inter- and intramolecular Diels-Alder reaction of a hexaenoate intermediate. 120:7411-7419. 1998
Energetic analysis of an engineered cation-π interaction in Staphylococcal nuclease. 120:7135-7136. 1998
Formation of discrete, functional assemblies and informational polymers through the hydrogen-bonding preferences of calixarene aryl and sulfonyl tetraureas. 120:3657-3663. 1998
From styrenes to enantiopure alpha-arylglycines in two steps. 120:1207-1217. 1998
Glycosylation of threonine of the repeating unit of RNA polymerase II with beta-linked N-acetylglucosame leads to a turnlike structure. 120:11567-11575. 1998
Kinetic implications of nonlinear effects in asymmetric synthesis. 120:13349-13353. 1998
Macroporous p-type silicon fabry-perot layers. Fabrication, characterization, and applications in biosensing. 120:12108-12116. 1998
Measurement of deoxyribose (3)j(hh) scalar couplings reveals protein binding-induced changes in the sugar puckers of the DNA. 120:821-822. 1998
Mechanistic studies of an antibody-catalyzed elimination reaction. 120:5160-5167. 1998
Mechanistic studies of an antibody-catalyzed pericyclic rearrangement. 120:1945-1958. 1998
Multistep convergent solution-phase combinatorial synthesis and deletion synthesis deconvolution. 120:7220-7225. 1998
NMR studies of Co.deglycoBleomycin A2 green and its complex with d(CCAGGCCTGG). 120:2239-2250. 1998
Noncovalent assembly of microhelix recognition by a class II tRNA synthetase. 120:3269-3270. 1998
Oriented self-assembly of cyclic peptide nanotubes in lipid membranes. 120:4417-4424. 1998
Probing the specificity of aminoglycoside ribosomal rna interactions with designed synthetic analogs. 120:1965-1978. 1998
Rules of stereoselectivity in tandem oxidative polycyclization reaction with rhenium(vii) oxides. 120:9076-9077. 1998
Segmental isotope labeling for protein NMR using peptide splicing. 120:5591-5592. 1998
Self-assembled molecular capsule catalyzes a Diels-Alder reaction. 120:7389-7390. 1998
Self-assembling cyclic beta(3)-peptide nanotubes as artificial transmembrane ion channels. 120:651-656. 1998
Self-folding cavitands. 120:12216-12225. 1998
Snar cyclizations to form cyclic peptidomimetics of beta-turns. 120:10768-10769. 1998
Solid and solution phase synthesis and biological evaluation of combinatorial sarcodictyin libraries. 120:10814-10826. 1998
Solid phase synthesis of macrocycles by an intramolecular ketophosphonate reaction. Synthesis of a (dl)-muscone library. 120:5132-5133. 1998
Soluble supports tailored for organic synthesis: Parallel polymer synthesis via sequential normal/living free radical processes. 120:9481-9495. 1998
Solution structure of the complex between the head-to-tail dimer of calicheamicin gamma(i)(1) oligosaccharide and a DNA duplex containing d(acct) and d(tcct) high-affinity binding sites. 120:7183-7191. 1998
Solution- and solid-phase synthesis of n-protected glycopeptide esters of the benzyl type as substrates for subtilisin-catalyzed glycopeptide couplings. 120:1979-1989. 1998
Structural rules governing self-assembly emerge from new molecular capsules. 120:819-820. 1998
Structure of the michaelis complex of an efficient antibody acyl transferase determined by transferred nuclear overhauser enhancement spectroscopy. 120:7395-7396. 1998
Subtle functional interactions in the RNA minor groove at a nonessential base pair. 120:9110-9111. 1998
Synthesis and screening of linear and cyclic oligocarbamate libraries. Discovery of high affinity ligands for gpiib/iiia. 120:7706-7718. 1998
Thermal atropisomerism of aglucovancomycin derivatives: preparation of (M,M,M)- and (P,M,M)-aglucovancomycins. 120:8920-8926. 1998
Total synthesis of eleutherobin and eleuthosides A and B. 120:8674-8680. 1998
Total synthesis of goniocin and cyclogoniodenin t. Unique biosynthetic implications. 120:4017-4018. 1998
Total synthesis of mucocin. 120:11279-11284. 1998
Total synthesis of nothapodytine B and (-)-mappicine. 120:1218-1222. 1998
Total synthesis of sarcodictyins A and B. 120:8661-8673. 1998
Transverse relaxation-optimized spectroscopy (trosy) for NMR studies of aromatic spin systems in c-13-labeled proteins. 120:6394-6400. 1998
Trapping of the C5 methylene intermediate in thymidylate synthase. 120:449-450. 1998
Vinyl sulfonate esters and vinyl sulfonamides: potent, irreversible inhibitors of cysteine proteases. 120:10994-10995. 1998
An antibody-catalyzed selenoxide elimination. 119:3623-3624. 1997
Computational study of the role of solvation effects in reverse turn formation in the tetrapeptides APGD and APGN. 119:4964-4971. 1997
Deconvolution of combinatorial oligonucleotide libraries by electrospray ionization tandem mass spectrometry. 119:3861-3867. 1997
Recognition of seven base pair sequences in the minor groove of DNA by ten-ring pyrrole-imidazole polyamide hairpins. 119:7636-7644. 1997
Rhodium-catalyzed intramolecular silylformylation of alkenes. 119:12416-12417. 1997
Variation in strength of an unconventional C-H to O hydrogen bond in an engineered protein cavity. 119:9083-9084. 1997
3D 15N−13C−13C chemical shift correlation spectroscopy in rotating solids. 119:8540-8546. 1997
A general and highly efficient solid phase synthesis of oligosaccharides. Total synthesis of a heptasaccharide phytoalexin elicitor (HPE). 119:449-450. 1997
A new method for the synthesis of fluoro-carbohydrates and glycosides using selectfluor. 119:11743-11746. 1997
A pentacoordinate oxorhenium(V) metallochelate elicits antibody catalysts for phosphodiester cleavage. 119:4088-4089. 1997
A permutation test for stabilization of polypeptide helices by sequence-dependent side chain interactions: Characterization of a helix initiation site within the myohemerythrin sequence 76-87. 119:1153-1154. 1997
Analysis of backbone hydrogen bonding in a beta-turn of Staphylococcal nuclease. 119:12667-12668. 1997
Antibody catalysis of b(ac)2 aryl carbamate ester hydrolysis: A highly disfavored chemical process. 119:2315-2316. 1997
Antibody-catalyzed enantioselective robinson annulation. 119:8131-8132. 1997
Bis(trimethylsilyl) peroxide extends the range of oxorhenium catalysts for olefin epoxidation. 119:11536-11537. 1997
Chemoenzymatic preparation of novel cyclic imine sugars and rapid biological activity evaluation using electrospray mass spectrometry and kinetic analysis. 119:8146-8151. 1997
Chemoenzymatic solution- and solid-phase synthesis of o-glycopeptides of the mucin domain of madcam-1. A general route to o-lacnac, o-sialyl-lacnac, and o-sialyl-lewis-x peptides. 119:8766-8776. 1997
Chiral capsules: asymmetric binding in calixarene-based dimers. 119:12671-12672. 1997
Density functional study on the electronic structures of model peroxidase compounds I and II. 119:11442-11451. 1997
Deuterium relaxation in a uniformly n-15-labeled homeodomain and its DNA complex. 119:3842-3843. 1997
Diffusion-limited size-selective ion sensing based on sam-supported peptide nanotubes. 119:11306-11312. 1997
Direct observation of aminoglycoside-RNA interactions by surface plasmon resonance. 119:3641-3648. 1997
Duocarmycin SA shortened, simplified, and extended agents: A systematic examination of the role of the DNA binding subunit. 119:4977-4986. 1997
Enzymatic glycoprotein synthesis: Preparation of ribonuclease glycoforms via enzymatic glycopeptide condensation and glycosylation. 119:2114-2118. 1997
Enzymatic synthesis of beta-hydroxy-alpha-amino acids based on recombinant d- and l-threonine aldolases. 119:11734-11742. 1997
Experimental and theoretical kinetic isotope effects for asymmetric dihydroxylation. Evidence supporting a rate-limiting ''(3+2)'' cycloaddition. 119:9907-9908. 1997
Exploitation of subtilisin bpn' as catalyst for the synthesis of peptides containing noncoded amino acids, peptide mimetics and peptide conjugates. 119:3942-3947. 1997
First evidence that the mechanism of catalytic hydrogenation with homogeneous palladium and rhodium catalysts is strongly influenced by substrate polarity. 119:5257-5258. 1997
Formation of bridge-methylated decalins by antibody-catalyzed tandem cationic cyclization. 119:5993-5998. 1997
Highly efficient epoxidation of olefins using aqueous h2o2 and catalytic methyltrioxorhenium/pyridine: Pyridine-mediated ligand acceleration. 119:6189-6190. 1997
Highly efficient ring closure of aromatic dialdehydes to macrocyclic allenes. 119:3429-3433. 1997
Highly selective Lewis acid catalyzed Diels-Alder reactions of acyclic (Z)-1,3-dienes. 119:7402-7403. 1997
Influenza neuraminidase inhibitors possessing a novel hydrophobic interaction in the enzyme active site: Design, synthesis, and structural analysis of carbocyclic sialic acid analogues with potent anti-influenza activity. 119:681-690. 1997
Intramolecular hydrogen bonding controls the exchange rates of guests in a cavitand. 119:9911-9912. 1997
Mathematical models of nonlinear effects in asymmetric catalysis: new insights based on the role of reaction rate. 119:12934-12939. 1997
Measurement of (3)j(c2'p) scalar couplings in a 17 kda protein complex with c-13,n-15-labeled DNA distinguishes the b-i and b-ii phosphate conformations of the DNA. 119:9901-9902. 1997
Mechanism of inactivation of neuronal nitric oxide synthase by n-omega-allyl-l-arginine. 119:10888-10902. 1997
Methods for the chemical synthesis and readout of self-encoded arrays of polypeptide analogues. 119:7917-7927. 1997
Modulation of reactivity in native chemical ligation through the use of thiol additives. 119:4325-4329. 1997
Mutational analysis of backbone hydrogen bonds in Staphylococcal nuclease. 119:7151-7152. 1997
New synthetic technology for the construction of 9-membered ring cyclic ethers. Construction of the EFGH ring skeleton of brevetoxin a. 119:8105-8106. 1997
New synthetic technology for the stereocontrolled construction of 1,1'-disaccharides and 1,1':1'',2-trisaccharides. Synthesis of the fg ring system of everninomicin 13,384-1. 119:9057-9058. 1997
New synthetic technology for the synthesis of aryl ethers: Construction of c-o-d and d-o-e ring model systems of vancomycin. 119:3421-3422. 1997
Palladium-catalyzed functionalization of lactones via their cyclic ketene acetal phosphates. Efficient new synthetic technology for the construction of medium and large cyclic ethers. 119:5467-5468. 1997
Preparation of specifically deuterated and 13C-labeled RNA for NMR studies using enzymatic synthesis. 119:12100-12108. 1997
Reactive immunization strategy generates antibodies with high catalytic proficiencies. 119:10251-10252. 1997
Reversed and sandwiched analogs of duocarmycin SA: Establishment of the origin of the sequence-selective alkylation of DNA and new insights into the source of catalysis. 119:4987-4998. 1997
Ring inversion dynamics of encapsulated cyclohexane. 119:11701-11702. 1997
Small molecules as structural and functional mimics of sialyl Lewis X tetrasaccharide in selectin inhibition: A remarkable enhancement of inhibition by additional negative charge and/or hydrophobic group. 119:8152-8158. 1997
Synthesis and assembly of new molecular hosts: solvation and the energetics of encapsulation. 119:77-85. 1997
Synthesis and cation-mediated electronic interactions of two novel classes of porphyrin-fullerene hybrids. 119:8363-8364. 1997
Synthesis of prostaglandin E-2 methyl ester on a soluble-polymer support for the construction of prostanoid libraries. 119:8724-8725. 1997
Synthesis of the tricyclic core of eleutherobin and sarcodictyins and total synthesis of sarcodictyin a. 119:11353-11354. 1997
Tandem oxidative cyclization with rhenium oxide. Total synthesis of 17,18-bisepi-goniocin. 119:12014-12015. 1997
The olefin metathesis approach to epothilone a and its analogues. 119:7960-7973. 1997
Total syntheses of epothilones A and B via a macrolactonization-based strategy. 119:7974-7991. 1997
Total syntheses of epothilones a and b. 119:10073-10092. 1997
Total synthesis of (+)-damavaricin D. 119:11331-11332. 1997
Total synthesis of (+)-duocarmycin A, epi-(+)-duocarmycin A and their unnatural enantiomers: assessment of chemical and biological properties. 119:311-325. 1997
Toward an understanding of the high enantioselectivity in the osmium-catalyzed asymmetric dihydroxylation .4. Electronic effects in amine-accelerated osmylations. 119:1840-1858. 1997
X-ray absorption studies on the mixed-valence and fully reduced forms of the soluble cu-a domains of cytochrome c oxidase. 119:6135-6143. 1997
Electrostatic catalysis of the Claisen rearrangement: Probing the role of Glu78 in Bacillus subtilis chorismate mutase by genetic selection. 118:3069-3070. 1996
Extending the applicability of native chemical ligation. 118:5891-5896. 1996
(-)-Sandramycin: total synthesis and characterization of DNA binding properties. 118:1629-1644. 1996
A 2,3'-substituted biphenyl-based amino acid facilitates the formation of a monomeric beta-hairpin-like structure in aqueous solution at elevated temperature. 118:5836-5845. 1996
A new class of pentacoordinate ribonuclease inhibitors: Synthesis, characterization, and inhibition studies of ribonucleoside and anhydropentofuranose oxorhenium(V) complexes. 118:12521-12527. 1996
A nitroxyl synthase catalytic antibody. 118:3550-3555. 1996
A re-examination of pressure effects on enantioselectivity in asymmetric catalytic hydrogenation. 118:1348-1353. 1996
A re-examination of two linear pentapeptides claimed to be serine protease mimics. 118:8787-8790. 1996
A structure-based library approach to kinase inhibitors. 118:7430-7431. 1996
A template-induced incipient collagen-like triple-helical structure. 118:5156-5157. 1996
A weak calcium binding site in subtilisin BPN' has a dramatic effect on protein stability. 118:1645-1650. 1996
Acetyl-terminated and template-assembled collagen-based polypeptides composed of gly-pro-hyp sequences .2. Synthesis and conformational analysis by circular dichroism, ultraviolet absorbance, and optical rotation. 118:10351-10358. 1996
Acetyl-terminated and template-assembled collagen-based polypeptides composed of gly-pro-hyp sequences .3. Conformational analysis by h-1-NMR and molecular modeling studies. 118:10359-10364. 1996
An antibody-catalyzed 2,3-elimination reaction. 118:11686-11687. 1996
An antibody-catalyzed isomerization reaction. 118:3811-3817. 1996
An olefin metathesis based strategy for the construction of the JKL, OPQ, and UVW ring systems of maitotoxin. 118:10335-10336. 1996
Analysis of active site residues in Escherichia coli chorismate mutase by site-directed mutagenesis. 118:1789-1790. 1996
Antibodies with thiol-S-transferase activity. 118:5474-5475. 1996
Antibody catalyzed terpenoid cyclization. 118:11654-11655. 1996
Antibody-catalyzed retro-aldol reaction. 118:6078-6079. 1996
Azatides: Solution and liquid phase syntheses of a new peptidomimetic. 118:2539-2544. 1996
Catalytic antibodies with peptidyl-prolyl cis-trans isomerase activity. 118:5496-5497. 1996
Collagen-based structures containing the peptoid residue n-isobutylglycine (nleu) .6. Conformational analysis of gly-pro-nleu sequences by h-1 NMR, cd, and molecular modeling. 118:10725-10732. 1996
Collagen-like triple helices incorporating peptoid residues. 118:10928-10929. 1996
Copying nature's mechanism for the decarboxylation of β-keto acids into catalytic antibodies by reactive immunization. 118:11720-11724. 1996
Cyclic guanidino-sugars with low pKa as transition-state analog inhibitors of glycosidases: Neutral instead of charged species are the active forms. 118:4227-4234. 1996
DNA carbohydrate interactions. Specific binding of head-to-head and head-to-tail dimers of the calicheamicin oligosaccharide to duplex DNA. 118:2303-2304. 1996
Diffusion filters for separation of solvent-protein and protein-protein nuclear overhauser effects (hydra). 118:11629-11634. 1996
Distal pocket polarity in the unusual ligand binding site of soluble guanylate cyclase: implications for the control of .NO binding. 118:8769-8770. 1996
Enantioselective total synthesis of (+)-duocarmycin A, epi-(+)-duocarmycin a, and their unnatural enantiomers. 118:2301-2302. 1996
Energetics of a low barrier hydrogen bond in nonpolar solvents. 118:8575-8579. 1996
Enzymatic/chemical synthesis and biological evaluation of seven-membered iminocyclitols. 118:7647-7652. 1996
Generalized dipeptidomimetic template: solution phase parallel synthesis of combinatorial libraries. 118:2109-2110. 1996
Homocarbonates as substrates for the enantioselective enzymatic protection of amines. 118:712-713. 1996
Inhibition of oleamide hydrolase catalyzed hydrolysis of the endogenous sleep-inducing lipid cis-9-octadecenamide. 118:5938-5945. 1996
Mutagenesis study of active site residues in chorismate mutase from Bacillus subtilis. 118:1787-1788. 1996
Nature of the potential energy surfaces for the SN1 reaction: A picosecond kinetic study of homolysis and heterolysis for diphenylmethyl chlorides. 118:2992-2997. 1996
Novel solution phase strategy for the synthesis of chemical libraries containing small organic molecules. 118:2567-2573. 1996
Olefin metathesis in cyclic ether formation. Direct conversion of olefinic esters to cyclic enol ethers with tebbe-type reagents. 118:1565-1566. 1996
Porphyrin metalation catalyzed by a small RNA molecule. 118:7012-7013. 1996
Preparation of specifically deuterated RNA for NMR studies using a combination of chemical and enzymatic synthesis. 118:7929-7940. 1996
Probing protein/protein interactions with mass spectrometry and isotopic labeling: Analysis of the p21/cdk2 complex. 118:5320-5321. 1996
Rapid combinatorial synthesis of aminoglycoside antibiotic mimetics: Use of a polyethylene glycol-linked amine and a neamine-derived aldehyde in multiple component condensation as a strategy for the discovery of new inhibitors of the hiv rna rev responsive element. 118:10150-10155. 1996
Rational design and synthesis of a 1,1-linked disaccharide that is 5 times as active as sialyl lewis x in binding to e-selectin. 118:9265-9270. 1996
Self-assembling peptide nanotubes. 118:43-50. 1996
Site-specific protein modification using a ketone handle. 118:8150-8151. 1996
Solid-phase synthesis of 6-deoxyoligosaccharides. 118:9998-9999. 1996
Soluble polymer-bound ligand-accelerated catalysis: Asymmetric dihydroxylation. 118:7632-7633. 1996
Solution structure of the head-to-head dimer of calicheamicin oligosaccharide domain and d(cgtaggatatcctacg)(2). 118:8817-8824. 1996
Structure determination of an endogenous sleep-inducing lipid, cis-9-octadecenamide (oleamide): A synthetic approach to the chemical analysis of trace quantities of a natural product. 118:580-590. 1996
Studies on the synthesis of nargenicin A(1): highly stereoselective synthesis of the complete carbon framework via the transannular Diels-Alder reaction of an 18-membered macrolide. 118:7502-7512. 1996
Synergistic inhibition of human alpha-1,3-fucosyltransferase v. 118:7653-7662. 1996
Synthesis of sialyl Lewis X mimetics and related structures using the glycosyl phosphite methodology and evaluation of E-selectin inhibition. 118:6826-6840. 1996
Synthesis, X-ray structure, and properties of fluorocyclopropane analogs of the duocarmycins incorporating the 9,9-difluoro-1,2,9,9a-tetrahydrocyclopropa c benzo e indol-4-one (F2CBI) alkylation subunit. 118:8860-8870. 1996
Tetramethoxy calix[4]arenes revisited: conformational control through self-assembly. 118:10002-10003. 1996
The cua center of a soluble domain from thermus cytochrome ba(3). An NMR investigation of the paramagnetic protein. 118:11658-11659. 1996
Total synthesis of swinholide a. 118:3059-3060. 1996
Toward an understanding of the high enantioselectivity in the osmium-catalyzed asymmetric dihydroxylation .3. New insights into isomeric forms of the putative osmaoxetane intermediate. 118:35-42. 1996
Useful information from axial peak magnetization in projected NMR experiments. 118:8146-8147. 1996
3(10) helixes in peptides and proteins as studied by modified Zimm-Bragg theory. 117:10098-10103. 1995
Chemical ligation of cysteine-containing peptides: synthesis of a 22 kDa tethered dimer of HIV-1 protease. 117:1881-1887. 1995
Metal-catalyzed dehydropolymerization of secondary stannanes to high-molecular-weight polystannanes. 117:9931-9940. 1995
A remarkably stable transition-metal benzyne complex - synthesis and structure of cp(pme(3))(eta(2)-c6h4)ta(et(2)c(2)b(4)h(4))(1). 117:1163-1164. 1995
Acyl transfer versus catalysis with avidin. 117:8482-8483. 1995
An antibody-catalyzed nucleophilic-substitution reaction at a primary carbon that appears to proceed by an ionization mechanism. 117:2367-2368. 1995
An organometallic diradical cycloaromatization reaction. 117:8045-8046. 1995
Analysis of hydrogen bonding strengths in proteins using unnatural amino acids. 117:9361-9362. 1995
Anti-metallocene antibodies: A new approach to enantioselective catalysis of the Diels-Alder reaction. 117:7041-7047. 1995
Antibody catalysis of multistep reactions - an aldol addition followed by a disfavored elimination. 117:9383-9387. 1995
Base-analog-induced aminoacylation of an RNA helix by a tRNA synthetase. 117:7253-7254. 1995
Catalytic antibodies in organic-synthesis - asymmetric-synthesis of (-)-alpha-multistriatin. 117:3653-3654. 1995
Chemical synthesis and biological evaluation of c-2 taxoids. 117:2409-2420. 1995
Combined osmium rhenium approach to synthesis of naturally-occurring polyethers. 117:1447-1448. 1995
Control of self-assembly and reversible encapsulation of xenon in a self-assembling dimer by acid-base chemistry. 117:85-88. 1995
Convergent functional groups. 16. Hydrolysis of phosphate triesters by a novel cleft. Influence of binding on overall rate acceleration. 117:2210-2213. 1995
DNA alkylation properties of CC-1065 and duocarmycin analogs incorporating the 2,3,10,10a-tetrahydrocyclopropa d benzo f quinol-5-one alkylation subunit - identification of subtle structural features that contribute to the regioselectivity of the adenine N3 alkylation reaction. 117:11647-11655. 1995
Design and synthesis of sialyl-Lewis X mimetics. 117:5395-5396. 1995
Enzymatic-synthesis and regeneration of 3'-phosphoadenosine 5'-phosphosulfate (PAPS) for regioselective sulfation of oligosaccharides. 117:8031-8032. 1995
Enzymatic-synthesis of hyaluronic-acid with regeneration of sugar nucleotides. 117:5869-5870. 1995
Key synthetic analogs of bleomycin A(2) that directly address the effect and role of the disaccharide - demannosylbleomycin A(2) and alpha-D-mannopyranosyldeglycobleomycin A(2). 117:7344-7356. 1995
Ligand recognition by e-selectin - synthesis, inhibitory activity, and conformational-analysis of bivalent sialyl-lewis-x analogs. 117:66-79. 1995
Linear free-energy analysis of hydrogen-bonding in proteins. 117:1157-1158. 1995
Macrocyclic peptide inhibitors of serine proteases - convergent total synthesis of cyclotheonamide-a and cyclotheonamide-b via a late-stage primary amine intermediate - study of thrombin inhibition under diverse conditions. 117:1225-1239. 1995
Mechanism of lithium dialkylamide-mediated ketone and imine deprotonations - an mndo study of monomer and open dimer pathways. 117:2166-2178. 1995
Mechanistic studies of antibody-catalyzed pyrimidine dimer photocleavage. 117:5453-5461. 1995
N-desmethyl derivatives of deoxybouvardin and RA-VII: synthesis and evaluation. 117:7364-7378. 1995
Observation of a RuCl2((S)-((-))-tol-binap) (2).N(C2H5)(3)-catalyzed isomerization-hydrogenation network. 117:12647-12648. 1995
Oxepane synthesis along a disfavored pathway - the rerouting of a chemical-reaction using a catalytic antibody. 117:2659-2660. 1995
Peptidomimetic host that binds a peptide guest affording a beta-sheet structure that subsequently self-assembles. A simple receptor mimic. 117:1655-1656. 1995
Probing the structural determinants of a catalytic RNA with isomerase activity. 117:10145-10146. 1995
Recombinant 2-deoxyribose-5-phosphate aldolase in organic-synthesis - use of sequential 2-substrate and 3-substrate aldol reactions. 117:3333-3339. 1995
Remarkable ability of different antibody catalysts to control and diversify the product outcome of cationic cyclization reactions. 117:3308-3309. 1995
Second definitive test of proposed models for the origin of the CC-1065 and duocarmycin DNA alkylation selectivity. 117:1443-1444. 1995
Selectivity in the inhibition of HIV and FIV protease - inhibitory and mechanistic studies of pyrrolidine-containing alpha-keto amide and hydroxyethylamine core structures. 117:11867-11878. 1995
Sequential 3-substrate and 4-substrate aldol reactions catalyzed by aldolases. 117:7585-7591. 1995
Sequential one-pot aldol reactions catalyzed by 2-deoxyribose-5-phosphate aldolase and fructose-1,6-diphosphate aldolase. 117:2947-2948. 1995
Shape and stereoselective cyclopropanation of alkenes catalyzed by iron porphyrins. 117:9194-9199. 1995
Solution-phase conformational studies of the cyclic peptide RA-VII: lithium-chloride perturbation of the conformational equilibria. 117:7357-7363. 1995
Spectroscopic studies on the designed metal-binding sites of the 43c9 single-chain antibody. 117:5627-5634. 1995
Structure and dynamics of self-assembling peptide nanotubes and the channel-mediated water organization and self-diffusion - a molecular-dynamics study. 117:9151-9158. 1995
Studies on the mechanism of action of isoniazid and ethionamide in the chemotherapy of tuberculosis. 117:5009-5010. 1995
Studies on the synthesis of aureolic acid antibiotics: highly stereoselective synthesis of aryl 2-deoxy-beta-glycosides via the Mitsunobu reaction and synthesis of the olivomycin A-B disaccharide. 117:2236-2250. 1995
Supramolecular design by covalent capture - design of a peptide cylinder via hydrogen-bond-promoted intermolecular olefin metathesis. 117:12364-12365. 1995
Synthesis and efficacy of square planar copper complexes designed to nucleate beta-sheet structure. 117:2533-2546. 1995
Synthesis and evaluation of the fully functionalized bleomycin A(2) metal-binding domain-containing the 2-O-(3-O-carbamoyl-alpha-D-mannopyranosyl)-alpha-L-gulopyranosyl disaccharide. 117:7338-7343. 1995
Synthesis and self-assembly of pseudo-spherical homo- and heterodimeric capsules. 117:12733-12745. 1995
The potential application of catalytic antibodies to protecting group removal - catalytic antibodies with broad substrate tolerance. 117:2123-2127. 1995
The streptomyces-glaucescens tcmkl polyketide synthase and tcmn polyketide cyclase genes govern the size and shape of aromatic polyketides. 117:6811-6821. 1995
Total synthesis of brevetoxin-b .1. Cdefg framework. 117:1171-1172. 1995
Total synthesis of brevetoxin-b .1. First generation strategies and new approaches to oxepane systems. 117:10227-10238. 1995
Total synthesis of brevetoxin-b .2. 2nd generation strategies and construction of the dioxepane region defg. 117:10239-10251. 1995
Total synthesis of brevetoxin-b .2. Completion. 117:1173-1174. 1995
Total synthesis of brevetoxin-b .3. Final strategy and completion. 117:10252-10263. 1995
Total synthesis of granditropone, grandirubrine, imerubrine, and isoimerubrine. 117:12452-12459. 1995
Total synthesis of natural and ent-fredericamycin-a. 117:11839-11849. 1995
Total synthesis of taxol .1. Retrosynthesis, degradation, and reconstitution. 117:624-633. 1995
Total synthesis of taxol .2. Construction of a-ring and c-ring intermediates and initial attempts to construct the abc ring-system. 117:634-644. 1995
Total synthesis of taxol .3. Formation of taxols abc ring skeleton. 117:645-652. 1995
Total synthesis of taxol .4. The final stages and completion of the synthesis. 117:653-659. 1995
Investigation of medium effects in a family of decarboxylase antibodies. 116:7959-7963. 1994
Monitoring catalytic activity by immunoassay: implications for screening. 116:6101-6106. 1994
Total synthesis of crystalline (+/-)-fredericamycin A. Use of radical spirocyclization. 116:11275-11286. 1994
(+)- and ent-(-)-duocarmycin SA and (+)- and ent-(-)-N-BOC-DSA DNA alkylation properties - alkylation site models that accommodate the offset AT-rich adenine N3 alkylation selectivity of the enantiomeric agents. 116:1635-1656. 1994
A new route to deoxythiosugars based on aldolases. 116:6191-6194. 1994
A novel and efficient synthesis of neolacto series gangliosides 3'-nlm(1) and 6'nlm(1). 116:1149-1150. 1994
An antibody-catalyzed oxy-Cope rearrangement. 116:2211-2212. 1994
An efficient antibody-catalyzed oxygenation reaction. 116:2167-2168. 1994
Antibody-catalyzed activation of unfunctionalized olefins for highly enantioselective asymmetric epoxidation. 116:803-804. 1994
Antibody-catalyzed prodrug activation. 116:2165-2166. 1994
Application of eta4-diene iron tricarbonyl complexes in acyclic stereocontrol: asymmetric synthesis of the as-indacene unit of ikarugamycin (a formal total synthesis). 116:2151-2152. 1994
Binding of hapten to a single chain catalytic antibody demonstrated by electrospray mass spectrometry. 116:7937-7938. 1994
CBI-TMI - synthesis and evaluation of a key analog of the duocarmycins - validation of a direct relationship between chemical solvolytic stability and cytotoxic potency and confirmation of the structural features responsible for the distinguishing behavior of enantiomeric pairs of agents. 116:7996-8006. 1994
Carbohydrate minor-groove interactions in the binding of calicheamicin gamma-1(i) to duplex DNA. 116:3709-3715. 1994
Channel-mediated transport of glucose across lipid bilayers. 116:10785-10786. 1994
Chemical and structural comparison of N-BOC-CBQ and N-BOC-CBI - identification and structural origin of an unappreciated but productive stability of the CC-1065 and duocarmycin SA alkylation subunits. 116:6461-6462. 1994
Chemical probe for glycosidic conformation in telomeric DNAs. 116:4479-4480. 1994
Convergent functional groups. 15. Studies of large and rigid molecular clefts. 116:5145-5149. 1994
Creation of a novel biosensor for zinc(II). 116:415-416. 1994
Crossing extreme mechanistic barriers by antibody catalysis: Syn elimination to a cis olefin. 116:6013-6014. 1994
Density-functional Poisson-Boltzmann calculations of redox potentials for iron-sulfur clusters. 116:11898-11914. 1994
Design, synthesis, and evaluation of CC-1065 and duocarmycin analogs incorporating the 2,3,10,10a-tetrahydro-1H-cyclopropa d benzo f quinol-5-one (CBQ) alkylation subunit - identification and structural origin of subtle stereoelectronic features that govern reactivity and regioselectivity. 116:11335-11348. 1994
Differential side chain hydration in a linear peptide containing a type VI turn. 116:12051-12052. 1994
Enantioselective total synthesis of (-)-chlorothricolide. 116:6457-6458. 1994
Engineering subtilisin for peptide coupling - studies on the effects of counterions and site-specific modifications on the stability and specificity of the enzyme. 116:6521-6530. 1994
Evidence for a cyclic mechanism in (eta(3)-allyl)palladium chemistry - promotion of beta-hydride elimination by unsaturated organometallics. 116:11151-11152. 1994
Hydrophobic cluster formation is necessary for dibenzofuran-based amino acids to function as beta-sheet nucleators. 116:3988-4005. 1994
Interaction of calicheamicin with duplex DNA - role of the oligosaccharide domain and identification of multiple binding modes. 116:3697-3708. 1994
Intracomplex catalysis of acylation reactions. 116:11592-11593. 1994
Intramolecular benzannulation reactions of chromium siloxycarbene complexes - regiochemical control and the xenochemical effect of alkyne additives. 116:10921-10933. 1994
Lithium dialkylamide mixed aggregation - an NMR spectroscopic study of the influence of hexamethylphosphoramide (hmpa). 116:9198-9202. 1994
Lithium dialkylamide mixed aggregation - mndo computational study of salt and solvent dependencies. 116:9187-9197. 1994
Mechanistic studies of an antibody-catalyzed elimination reaction. 116:2261-2270. 1994
Mechanistic studies of the oxidation of isoniazid by the catalase peroxidase from Mycobacterium tuberculosis. 116:7425-7426. 1994
Nanoscale tubular ensembles with specified internal diameters - design of a self-assembled nanotube with a 13 Å pore. 116:6011-6012. 1994
New evidence for template effects in a self-replicating system. 116:8823-8824. 1994
Nmr order parameters of biomolecules - a new analytical representation and application to the gaussian axial fluctuation model. 116:8426-8427. 1994
Recognition of DNA by synthetic antibodies. 116:2161-2162. 1994
Role of geometrical factors in template effects. 116:10296-10297. 1994
Role of the CC-1065 and duocarmycin N-2 substituent - validation of a direct relationship between solvolysis chemical-stability and in-vitro biological potency. 116:5523-5524. 1994
Self-replicating molecules: a second generation. 116:8877-8884. 1994
Sequence-corrected n-15 random coil chemical-shifts. 116:8466-8469. 1994
Solid-phase chemical-enzymatic synthesis of glycopeptides and oligosaccharides. 116:1135-1136. 1994
Solution-phase and solid-phase synthesis of inhibitors of helicobacter-pylori attachment and e-selectin-mediated leukocyte adhesion. 116:11315-11322. 1994
Stereoselective antibody-catalyzed oxime formation. 116:1145-1146. 1994
Synthesis of carbohydrates via tandem use of the osmium-catalyzed asymmetric dihydroxylation and enzyme-catalyzed aldol addition-reactions. 116:558-561. 1994
Synthesis of novel taxoids. 116:1591-1592. 1994
Synthesis, structure, and reactivity of (mu-oxo)bis(mu-carboxylato)diiron(III) complexes of a dinucleating dicarboxylate ligand, stable models for non-heme diiron protein cores. 116:5196-5205. 1994
Total syntheses of (+)-p-3a, epi-(-)-p-3a, and (-)-desacetamido p-3a. 116:82-92. 1994
Total synthesis of balanol. 116:8402-8403. 1994
Total synthesis of bleomycin A(2) and related agents .4. Synthesis of the disaccharide subunit - 2-O-(3-O-carbamoyl-alpha-D-mannopyranosyl)-L-gulopyranose and completion of the total synthesis of bleomycin a(2). 116:5647-5656. 1994
Total synthesis of bleomycin-A(2) and related agents .1. Synthesis and DNA-binding properties of the extended C-terminus - tripeptide-S, tetrapeptide-S, pentapeptide-S, and related agents. 116:5607-5618. 1994
Total synthesis of bleomycin-A(2) and related agents .2. Synthesis of (-)-pyrimidoblamic acid, epi-(+)-pyrimidoblamic acid, (+)-desacetamidopyrimidoblamic acid, and (-)-descarboxamidopyrimidoblamic acid. 116:5619-5630. 1994
Total synthesis of bleomycin-A(2) and related agents .3. Synthesis and comparative-evaluation of deglycobleomycin-A(2), epideglycobleomycin-A(2), deglycobleomycin-A(1), and desacetamidodeglycobleomycin, descarboxamidodeglycobleomycin, desmethyldeglycobleomycin, and desimidazolyldeglycobleomycin-A(2). 116:5631-5646. 1994
Total synthesis of bouvardin, O-methylbouvardin, and O-methyl-N-9-desmethylbouvardin. 116:8544-8556. 1994
Total synthesis of truncated brevetoxin-b afghijk. 116:9371-9372. 1994
Toward an understanding of the high enantioselectivity in the osmium-catalyzed asymmetric dihydroxylation (ad) .1. Kinetics. 116:1278-1291. 1994
Toward an understanding of the high enantioselectivity in the osmium-catalyzed asymmetric dihydroxylation .2. A qualitative molecular mechanics approach. 116:8470-8478. 1994
Transport of adenine mononucleoside and dinucleoside monophosphates across liquid membranes and extraction of oligonucleotides with synthetic carriers. 116:5501-5502. 1994
Unprecedented asymmetric aldol reactions with 3 aldehyde substrates catalyzed by 2-deoxyribose-5-phosphate aldolase. 116:8422-8423. 1994
Water-soluble receptors for cyclic-AMP and their use for evaluating phosphate-guanidinium interactions. 116:3279-3284. 1994
[(Z)-gamma-[(Diisopropylidene-alpha-D-mannopyranosyl)oxy]allyl]tributylstannane: a new chiral reagent for the asymmetric alpha-hydroxyallylation of aldehydes. 116:8536-8543. 1994
Correlating hydration shell structure with amino acid hydrophobicity. 115:3336-3337. 1993
(-)-sandramycin - total synthesis and preliminary DNA-binding properties. 115:11624-11625. 1993
A catalytic antibody model for plp-dependent decarboxylases. 115:2515-2516. 1993
A dramatic ligand effect on the relative reactivities of substituted alkenes with osmium-tetroxide. 115:7047-7048. 1993
A highly specific metal-activated catalytic antibody. 115:4906-4907. 1993
A novel strategy for synthesis of ganglioside-gm3 using an enzymatically produced sialoside glycosyl donor. 115:1603-1605. 1993
Antibody-catalyzed enantioselective epoxide hydrolysis. 115:4893-4894. 1993
Antibody-catalyzed hydrolysis of enol ethers. 115:3909-3917. 1993
Application of the steric directing group strategy to the stereoselective synthesis of the octahydronaphthalene substructure of kijanolide and tetronolide. 115:2268-2278. 1993
Catalytic antibodies from combinatorial libraries. 115:357-358. 1993
Catalytic asymmetric dihydroxylation of tetrasubstituted olefins. 115:8463-8464. 1993
Characterization of amino-acid side-chain dynamics in a zinc-finger peptide using c-13 NMR-spectroscopy and time-resolved fluorescence spectroscopy. 115:6333-6345. 1993
Combined use of trans-sialidase and sialyltransferase for enzymatic-synthesis of alpha-neuac2-- 3-beta-gal-or. 115:7862-7863. 1993
Convenient total synthesis of a 4-helix TASP molecule by chemoselective ligation. 115:7263-7266. 1993
Convergent functional groups. 13. High-affinity complexation of adenosine derivatives within induced binding pockets. 115:3548-3557. 1993
D, l- and meso-isochrysohermidin - total synthesis and interstrand DNA cross-linking. 115:11418-11425. 1993
De-novo design and synthesis of somatostatin nonpeptide peptidomimetics utilizing beta-d-glucose as a novel scaffolding. 115:12550-12568. 1993
Design, synthesis, and partial characterization of water-soluble beta-sheets stabilized by a dibenzofuran-based amino acid. 115:3790-3791. 1993
Detection of 2 histidyl ligands to cu-a of cytochrome-oxidase by 35-ghz endor - n-14,15 and cu-63,65 endor studies of the cu-a site in bovine heart cytochrome-aa(3) and cytochrome-caa(3) and cytochrome-ba(3) from thermus-thermophilus. 115:10888-10894. 1993
Determination of local ligand conformations in slowly tumbling proteins by homonuclear 2d and 3d NMR - application to heme propionates in leghemoglobin. 115:6238-6246. 1993
Engineering metal coordination sites into the antibody light-chain. 115:4449-4456. 1993
Enzymatic-synthesis of N-linked and O-linked glycopeptides. 115:5893-5901. 1993
Evidence of ca2+-dependent carbohydrate association through ion spray mass-spectrometry. 115:2877-2881. 1993
Identification of the active catalyst in the rhodium porphyrin-mediated cyclopropanation of alkenes. 115:1656-1660. 1993
Isolation and structure determination of 2-amino-2-deoxyisochorismate - an intermediate in the biosynthesis of anthranilate. 115:816-817. 1993
Kinetic resolution of racemic olefins via asymmetric dihydroxylation. 115:7864-7865. 1993
Ligand recognition by e-selectin - analysis of conformation and activity of synthetic monomeric and bivalent sialyl lewis-x analogs. 115:7549-7550. 1993
Molecular design, chemical synthesis, kinetic-studies, calculations, and biological studies of novel enediynes equipped with triggering, detection, and deactivating devices - model dynemicin-a epoxide and cis-diol systems. 115:7944-7953. 1993
Molecular recognition in water: new receptors for adenine derivatives. 115:797-798. 1993
Nmr1 detection of hydration water in the intermolecular interface of a protein-DNA complex. 115:1189-1190. 1993
Probing the role of lysine 16 in Ras p(21) protein with unnatural amino acids. 115:6414-6415. 1993
Protein biosynthesis with conformationally restricted amino acids. 115:4359-4360. 1993
Reduced dimensionality in triple-resonance NMR experiments. 115:9307-9308. 1993
Reversibility of the duocarmycin-A and SA DNA alkylation reaction. 115:9872-9873. 1993
Singlet oxygen oxidation of bipyrroles - total synthesis of d,l-isochrysohermidin and meso-isochrysohermidin. 115:8457-8458. 1993
Structure of lithium hexamethyldisilazide (lihmds) in the presence of hexamethylphosphoramide (hmpa) - spectroscopic and computational studies of monomers, dimers, and triple ions. 115:3475-3483. 1993
Synthesis and use of glycosyl phosphites - an effective route to glycosyl phosphates, sugar nucleotides, and glycosides. 115:2260-2267. 1993
Synthesis of 3-deoxy-d-manno-2-octulosonic acid (kdo) and its analogs based on kdo aldolase-catalyzed reactions. 115:413-421. 1993
Synthesis of phospholipid inhibitor conjugates by enzymatic transphosphatidylation with phospholipase-d. 115:10487-10491. 1993
Synthetic methods for the implementation of encoded combinatorial chemistry. 115:9812-9813. 1993
The energetic advantage of 5-exo versus 6-endo epoxide openings - a preference overwhelmed by antibody catalysis. 115:8453-8454. 1993
The origin of high enantioselectivity in the dihydroxylation of olefins using osmium tetraoxide and cinchona alkaloid catalysts. 115:12226-12227. 1993
Total synthesis and preliminary evaluation of (+)-duocarmycin and ent-(-)-duocarmycin SA. 115:9025-9036. 1993
Total synthesis of (+)-piperazinomycin. 115:11426-11433. 1993
Total synthesis of calicheamicin-gamma-1(i) .1. Synthesis of the oligosaccharide fragment. 115:7593-7611. 1993
Total synthesis of calicheamicin-gamma-1(i) .2. Development of an enantioselective route to (-)-calicheamicinone. 115:7612-7624. 1993
Total synthesis of calicheamicin-gamma-1(i) .3. The final stages. 115:7625-7635. 1993
Total synthesis of cycloisodityrosine, RA-VII, deoxybouvardin, and N29-desmethyl-RA-VII - identification of the pharmacophore and reversal of the subunit functional roles. 115:3420-3430. 1993
Total synthesis of hemibrevetoxin-b and (7a-alpha)-epi-hemibrevetoxin-b. 115:3558-3575. 1993
Total synthesis of naturally-occurring acetogenins - solamin and reticulatacin. 115:4891-4892. 1993
Total synthesis of rapamycin. 115:4419-4420. 1993
Total synthesis of streptonigrone. 115:10733-10741. 1993
Total synthesis of sulfated le(x) and le(a)-type oligosaccharide selectin ligands. 115:8843-8844. 1993
Defining hydrophobicity: probing the structure of solute-induced hydration shells by Fourier transform infrared spectroscopy. 114:4336-4339. 1992
Direct observation of a ternary complex between the dimeric enzyme HIV-1 protease and a substrate-based inhibitor. 114:3992-3993. 1992
A chromogenic assay for screening large antibody libraries. 114:1486-1487. 1992
A convergent approach to protein design - metal ion-assisted spontaneous self-assembly of a polypeptide into a triple-helix bundle protein. 114:825-831. 1992
A dibenzofuran-based amino acid designed to nucleate antiparallel beta-sheet structure: evidence for intramolecular hydrogen-bond formation. 114:8316-8318. 1992
A new approach toward the inhibition of ribonucleases - a water-stable ribonucleoside technetium chelate. 114:1488-1489. 1992
A new chiral auxiliary for asymmetric thermal reactions: high stereocontrol in radical addition, allylation, and annulation reactions. 114:7007-7018. 1992
A transition-state model for the rhodium porphyrin-catalyzed cyclopropanation of alkenes by diazo esters. 114:8336-8338. 1992
An antibody-catalyzed dehydration reaction. 114:6573-6574. 1992
Beta-sialyl phosphite and phosphoramidite - synthesis and application to the chemoenzymatic synthesis of cmp-sialic acid and sialyl oligosaccharides. 114:8748-8750. 1992
Catalytic asymmetric dihydroxylation of cis-disubstituted olefins. 114:7568-7570. 1992
Chemical-enzymatic synthesis and conformational-analysis of sialyl lewis-x and derivatives. 114:9283-9298. 1992
Cluster sialoside inhibitors for influenza-virus - synthesis, NMR, and biological studies. 114:8363-8375. 1992
Conformational studies of sialyl lewis-x in aqueous-solution. 114:5452-5454. 1992
DNA alkylation properties of enhanced functional analogs of cc-1065 incorporating the 1,2,9,9a-tetrahydrocyclopropa 1,2-c benz 1,2-e indol-4-one (cbi) alkylation subunit. 114:5487-5496. 1992
DNA carbohydrate interactions - specific binding of the calicheamicin-gamma-1i oligosaccharide with duplex DNA. 114:7555-7557. 1992
Deoxyribose-5-phosphate aldolase as a catalyst in asymmetric aldol condensation. 114:741-748. 1992
Design of an artificial 4-helix bundle metalloprotein via a novel ruthenium(ii)-assisted self-assembly process. 114:4000-4002. 1992
Design, synthesis, and study of simple monocyclic conjugated enediynes - the 10-membered ring enediyne moiety of the enediyne anticancer antibiotics. 114:7360-7371. 1992
Determination of structures of solvated lithium dialkylamides by semiempirical (mndo) methods - comparison of theory and experiment. 114:2112-2121. 1992
Enantioselective total synthesis of (-)-calicheamicinone. 114:3134-3136. 1992
Functional analogs of CC-1065 and the duocarmycins incorporating the 9A-(chloromethyl)-1,2,9,9a-tetrahydrocyclopropa c benz e indol-4-one (C2BI) alkylation subunit - synthesis and preliminary DNA alkylation studies. 114:9318-9327. 1992
Highly enantioselective protonation catalyzed by an antibody. 114:2257-2258. 1992
Intramolecular benzannulation reactions of manganese carbene complexes. 114:8735-8736. 1992
LCAO X alpha calculation of the magnetic exchange interactions in a Mn(IV)Mn(III)3 cubane complex: relevance to the water oxidation center of photosystem II. 114:6109-6119. 1992
Molecular design and chemical synthesis of potent enediynes .1. Dynemicin model systems equipped with n-tethered triggering devices. 114:8890-8907. 1992
Molecular design and chemical synthesis of potent enediynes .2. Dynemicin model systems equipped with c-3 triggering devices and evidence for quinone methide formation in the mechanism of action of dynemicin-a. 114:8908-8921. 1992
Nonpeptidal peptidomimetics with a beta-d-glucose scaffolding - a partial somatostatin agonist bearing a close structural relationship to a potent, selective substance-p antagonist. 114:9217-9218. 1992
Novel tight-binding inhibitors of leukotriene-a(4) hydrolase. 114:6552-6553. 1992
Organotransition-metal metallacarboranes .26. Carborane ligands in organometallic chemistry - a new class of fischer carbene complexes. 114:8733-8735. 1992
Overproduction of cmp-sialic acid synthetase for organic-synthesis. 114:3901-3910. 1992
Polypeptide hydration in mixed-solvents at low-temperatures. 114:7093-7095. 1992
Psi PO2-CH2N+ , a new amide bond replacement - potent, slow-binding inhibition of the HIV protease. 114:7604-7606. 1992
Redox-controlled bergman cycloaromatizations - designed enediynes with DNA-cleaving properties and antitumor-activity. 114:9279-9282. 1992
Remarkable regioselectivity in the chemical glycosylation of glycal acceptors - a concise solution to the synthesis of sialyl-lewis-x glycal. 114:8329-8331. 1992
Selective asymmetric dihydroxylation of dienes. 114:7570-7571. 1992
Site-specific isotopic labeling of proteins for NMR studies. 114:7959-7961. 1992
Specificity, inhibition, and synthetic utility of a recombinant human alpha-1,3-fucosyl-transferase. 114:7321-7322. 1992
Spectroscopic studies of a transcriptional activation peptide. 114:362-363. 1992
Stereospecific antibody-catalyzed reduction of an alpha-keto amide. 114:780-781. 1992
Structure and reactivity of lithium diisopropylamide in the presence of n,n,n',n'-tetramethylethylenediamine. 114:5100-5110. 1992
Substituent effects on an antibody-catalyzed hydrolysis of phenyl-esters - further evidence for an acyl-antibody intermediate. 114:3528-3534. 1992
Synthetic replicators and extrabiotic chemistry. 114:4529-4532. 1992
Total synthesis of (+)-duocarmycin SA. 114:10056-10058. 1992
Total synthesis of hemibrevetoxin-b. 114:7935-7936. 1992
Total synthesis of sialyl dimeric lex. 114:3126-3128. 1992
Total synthesis of the nodrm-iv factors, the rhizobium nodulation signals. 114:8701-8702. 1992
Unusual stereoselectivity in sialic-acid aldolase-catalyzed aldol condensations - synthesis of both enantiomers of high-carbon monosaccharides. 114:10138-10145. 1992
(+)-CC-1065 DNA alkylation - key studies demonstrating a noncovalent binding selectivity contribution to the alkylation selectivity. 113:3980-3983. 1991
(+)-CC-1065 DNA alkylation - observation of an unexpected relationship between cyclopropane electrophile reactivity and the intensity of DNA alkylation. 113:2779-2780. 1991
A complete change of stereoselectivity in sialic-acid aldolase reactions - a novel synthetic route to the kdo type of 9-carbon-l sugars. 113:7816-7818. 1991
A general and efficient route for chemical aminoacylation of transfer RNAs. 113:2722-2729. 1991
A highly efficient multienzyme system for the one-step synthesis of a sialyl trisaccharide - insitu generation of sialic-acid and n-acetyllactosamine coupled with regeneration of udp-glucose, udp-galactose, and cmp-sialic acid. 113:6300-6302. 1991
A synthetic receptor for dinucleotides. 113:9424-9425. 1991
Active-site-directed modification of subtilisin. 113:2259-2263. 1991
An antibody-catalyzed cis trans isomerization reaction. 113:2319-2321. 1991
Antibody bait and switch catalysis - a survey of antigens capable of inducing abzymes with acyl-transfer properties. 113:5427-5434. 1991
Antibody-catalyzed bimolecular imine formation. 113:6670-6672. 1991
Antibody-catalyzed hydrolysis of phosphate monoesters. 113:9397-9398. 1991
Asymmetric induction via a catalytic antibody. 113:7763-7764. 1991
Catalytic antibodies with acyl-transfer capabilities - mechanistic and kinetic investigations. 113:291-297. 1991
Construction of a light-activated protein by unnatural amino acid mutagenesis. 113:2758-2760. 1991
Convergent functional groups create a microenvironment for enolization catalysis. 113:1453-1454. 1991
Convergent functional groups. 10. Molecular recognition of neutral substrates. 113:201-209. 1991
Enantiofacial protonation by catalytic antibodies. 113:8528-8529. 1991
Engineering protein specificity: gene manipulation with semisynthetic nucleases. 113:9398-9400. 1991
Engineering subtilisin for reaction in dimethylformamide. 113:683-684. 1991
Enzyme-catalyzed aldol condensation for asymmetric-synthesis of azasugars - synthesis, evaluation, and modeling of glycosidase inhibitors. 113:6187-6196. 1991
Enzyme-catalyzed synthesis of sialyl oligosaccharide with insitu regeneration of cmp-sialic acid. 113:4698-4700. 1991
Epoxyquinones from 2,5-dihydroxyacetanilide - opposite facial specificity in the epoxidation by enzymes from streptomyces ll-c10037 and streptomyces mpp 3051. 113:684-686. 1991
General-approach to the synthesis of short alpha-helical peptides. 113:9391-9392. 1991
Intramolecular motions of a zinc finger DNA-binding domain from xfin characterized by proton-detected natural abundance c-12 heteronuclear NMR-spectroscopy. 113:4371-4380. 1991
Inverse electron demand Diels-Alder reactions of N-sulfonyl alpha,beta-unsaturated imines - a general-approach to implementation of the 4-pi participation of 1-aza-1,3-butadienes in Diels-Alder reactions. 113:1713-1729. 1991
Isolation and characterization of the duocarmycin adenine DNA adduct. 113:6645-6649. 1991
Kinetic studies and modeling of a self-replicating system. 113:8831-8839. 1991
Kinetic-studies of superoxide dismutases - properties of the manganese-containing protein from thermus-thermophilus. 113:4069-4076. 1991
Mechanism of asymmetric epoxidation .1. Kinetics. 113:106-113. 1991
Mechanism of asymmetric epoxidation .2. Catalyst structure. 113:113-126. 1991
New chiral auxiliary for asymmetric thermal reactions: high regio- and beta-stereoselectivity in asymmetric radical addition reactions to mixed fumarimides. 113:5918-5920. 1991
New molecular complements to imides. Complexation of thymine derivatives. 113:5125-5127. 1991
Novel enediynes equipped with triggering and detection devices - isolation of cis-diol models of the dynemicin-a cascade. 113:9878-9880. 1991
On the structure of lithium 2,2,6,6-tetramethylpiperidide (litmp) and lithium diisopropylamide (lda) in the presence of hexamethylphosphoramide (hmpa) - structure-dependent distribution of cyclic and open dimers, ion triplets, and monomers. 113:5751-5757. 1991
Palladium-mediated stereocontrolled reductive amination of azido sugars prepared from enzymatic aldol condensation - a general-approach to the synthesis of deoxy aza sugars. 113:6678-6680. 1991
Probing the acceptor specificity of beta-1,4-galactosyltransferase for the development of enzymatic-synthesis of novel oligosaccharides. 113:8137-8145. 1991
Proton proton overhauser effects of receptor-bound cyclosporine-a observed with the use of a heteronuclear-resolved half-filter experiment. 113:4676-4678. 1991
Proton-exchange with internal water-molecules in the protein bpti in aqueous-solution. 113:4363-4364. 1991
Pseudomonas-oleovorans monooxygenase catalyzed asymmetric epoxidation of allyl alcohol derivatives and hydroxylation of a hypersensitive radical probe with the radical ring-opening rate exceeding the oxygen rebound rate. 113:5878-5880. 1991
Redirecting the immune response: ligand-mediated immunogenicity. 113:1861-1862. 1991
Sigmoidal growth in a self-replicating system. 113:9422-9423. 1991
Soft stereoelectronic effects at carboxyl oxygen. 113:2247-2253. 1991
Synthesis and chemistry of dynemicin-a models. 113:3106-3114. 1991
Synthesis of cluster sialoside inhibitors for influenza-virus. 113:5865-5866. 1991
Total synthesis of (+/-)-cis-trikentrin-A and (+/-)-trans-trikentrin-A - Diels-Alder reactions of heteroaromatic azadienes. 113:4230-4234. 1991
Total synthesis of deoxybouvardin and RA-VII - macrocyclization via an intramolecular Ullmann reaction. 113:1427-1429. 1991
A new strategy for selective protein cleavage. 112:3249-3250. 1990
A self-replicating system. 112:1249-1250. 1990
Acyclic diastereoselective synthesis using tartrate ester modified crotylboronates: double asymmetric reactions with alpha-methyl chiral aldehydes and synthesis of the C19-C29 segment of rifamycin S. 112:6348-6359. 1990
An antibody-catalyzed bimolecular Diels-Alder reaction. 112:7430-7431. 1990
Asymmetric-synthesis using diisopropyl tartrate modified (E)-crotylboronates and (Z)-crotylboronates: preparation of the chiral crotylboronates and reactions with achiral aldehydes. 112:6339-6348. 1990
Bait and switch strategy for obtaining catalytic antibodies with acyl-transfer capabilities. 112:1274-1275. 1990
Bridging of macrodithionolactones to bicyclic systems - synthesis and modeling of oxapolycyclic frameworks. 112:3040-3054. 1990
Convergent functional groups. 8. Flexible model receptors for adenine derivatives. 112:8408-8414. 1990
Convergent functional groups. 9. Complexation in new molecular clefts. 112:8902-8906. 1990
DNA cleavage and antitumor-activity of designed molecules with conjugated phosphine oxide-allene-ene-yne functionalities. 112:7825-7826. 1990
Deoxyribose-5-phosphate aldolase as a synthetic catalyst. 112:2013-2014. 1990
Dithiatopazine and related systems - synthesis, chemistry, x-ray crystallographic analysis and calculations. 112:3029-3039. 1990
Duocarmycin pyrindamycin DNA alkylation properties and identification, synthesis, and evaluation of agents incorporating the pharmacophore of the duocarmycin pyrindamycin alkylation subunit - identification of the CC-1065-duocarmycin common pharmacophore. 112:8961-8971. 1990
Enzymes as synthetic catalysts - mechanistic and active-site considerations of natural and modified chymotrypsin. 112:5313-5320. 1990
Enzymes in organic synthesis: use of subtilisin and a highly stable mutant derived from multiple site-specific mutations. 112:945-953. 1990
Exchange of amide protons. Effect of intramolecular hydrogen bonding. 112:3122-3125. 1990
High-efficiency synthesis of sialyloligosaccharides and sialoglycopeptides. 112:9308-9309. 1990
Immobilized catalytic antibodies in aqueous and organic-solvents. 112:8886-8888. 1990
Intramolecular acyl radical alkene addition-reactions - macrocyclization reactions. 112:4008-4011. 1990
Molecular recognition. Asymmetric complexation of diketopiperazines. 112:6144-6145. 1990
New nuclear-magnetic-resonance experiment for measurements of the vicinal coupling-constants 3jhn-alpha in proteins. 112:3663-3665. 1990
New synthetic strategies for the construction of medium-size cyclic ethers - stereocontrolled synthesis of the bcd ring framework of brevetoxin-a. 112:3696-3697. 1990
Novel stereocontrolled synthesis of the nonacene ring-system of brevetoxin-a - conformational reactivity effects in 9-membered rings. 112:4988-4989. 1990
Novel strategy for the construction of the oligosaccharide fragment of calicheamicin-gamma-1-alpha-i - synthesis of the abc skeleton. 112:4085-4086. 1990
Peptide architecture - design of stable alpha-helical metallopeptides via a novel exchange-inert ruiii complex. 112:9633-9635. 1990
Peroxidase activity of an antibody heme complex. 112:9414-9415. 1990
Relative hydrogen-bonding affinities of imides and lactams. 112:3215-3217. 1990
Secondary structure nucleation in peptides - transition-metal ion stabilized alpha-helices. 112:1630-1632. 1990
Site-specific cleavage of duplex DNA with a lambda-repressor Staphylococcal nuclease hybrid. 112:4579-4580. 1990
Specific deuteration strategy for enhancing direct nuclear overhauser effects in high-molecular-weight complexes. 112:8183-8185. 1990
Stereoelectronic effects in cyclization reactions. 112:3685-3686. 1990
Synthesis and evaluation of aborted and extended CC-1065 functional analogs - (+)-CPI-PDE-1, and (-)-CPI-PDE-1, (+)-CPI-PDE-1, and (-)-CPI-CDPI1, and (+/-)-CPI-PDE-i1, (+)-CPI-PDE-i1, and (-)-CPI-CDPI3 - preparation of key partial structures and definition of an additional functional-role of the CC-1065 central and right-hand subunits. 112:4623-4632. 1990
Synthesis of dynemicin-a models. 112:7416-7418. 1990
Synthesis of medium-sized ring ethers from thionolactones - applications to polyether synthesis. 112:6263-6276. 1990
Synthesis of n-(phenylsulfonyl)-CI, N-((tert-butyloxy)carbonyl)-CI, CI-CDPI1, and CI-CDPI2 - CC-1065 functional analogs incorporating the parent 1,2,7,7a-tetrahydrocycloprop 1,2-c indol-4-one (CI) left-hand subunit. 112:5230-5240. 1990
Tandem free-radical alkene addition-reactions of acyl radicals. 112:4003-4008. 1990
Total synthesis of the oligosaccharide fragment of calicheamicin gamma-1i. 112:8193-8195. 1990
Total synthesis of the tumor-associated le(x) family of glycosphingolipids. 112:3693-3695. 1990
Use of a double-half-filter in 2-dimensional 1h nuclear-magnetic-resonance studies of receptor-bound cyclosporine. 112:9015-9016. 1990
1,1'-carbonylbis(3-methylimidazolium) triflate: an efficient reagent for aminoacylations. 111:4856-4859. 1989
A general-solution to implementing the 4-p participation of 1-aza-1,3-butadienes in Diels-Alder reactions - inverse electron demand Diels-Alder reactions of alpha,beta-unsaturated n-benzenesulfonyl imines. 111:1517-1519. 1989
A highly stereoselective synthesis of (+)-olivin, the aglycon of olivomycin A. 111:2984-2995. 1989
A mechanistic insight leads to a greatly improved osmium-catalyzed asymmetric dihydroxylation process. 111:1123-1125. 1989
A semisynthetic catalytic antibody. 111:1929-1931. 1989
Activation of 6-endo over 5-exo hydroxy epoxide openings - stereoselective and ring selective synthesis of tetrahydrofuran and tetrahydropyran systems. 111:5330-5334. 1989
Activation of 7-endo over 6-exo epoxide openings - synthesis of oxepane and tetrahydropyran systems. 111:5335-5340. 1989
Aminolysis of benzoyl fluorides in water. 111:8479-8484. 1989
Automated stereospecific h-1-NMR assignments and their impact on the precision of protein-structure determinations in solution. 111:3997-4004. 1989
Biosynthesis of antibiotic ll-c10037-alpha - the steps beyond 3-hydroxyanthranilic acid. 111:7932-7938. 1989
Conformational study of cinchona alkaloids - a combined NMR, molecular mechanics, and x-ray approach. 111:8069-8076. 1989
Cyclizations of hydroxy dithioketals - new synthetic technology for the construction of oxocenes and related medium-ring systems. 111:5321-5330. 1989
Experimental-observation of orientational dispersion in the peptide backbone of the gramicidin cation channel. 111:400-401. 1989
Free-radical cyclizations - application to the total synthesis of dl-pleurotin and dl-dihydropleurotin acid. 111:7507-7519. 1989
Intramolecular catalysis of enolization: a probe for stereoelectronic effects at carboxyl oxygen. 111:4503-4505. 1989
Kinetic role of the alkaloid ligands in asymmetric catalytic dihydroxylation. 111:737-739. 1989
Mechanism of solvolysis of substituted benzoyl halides. 111:8470-8479. 1989
Metalloselective anti-porphyrin monoclonal-antibodies. 111:2344-2346. 1989
Molecular recognition with convergent functional groups. 6. Synthetic and structural studies with a model receptor for nucleic acid components. 111:1082-1090. 1989
Molecular recognition with convergent functional groups. 7. Energetics of adenine binding with model receptors. 111:1090-1094. 1989
N-h bond length determinations and implications for the gramicidin channel conformation and dynamics from n-15-h-1 dipolar interactions. 111:1910-1912. 1989
Neutron-diffraction structure-analysis of a hexanuclear copper hydrido complex, h6cu6 p(para-tolyl)3 6 - an unexpected finding. 111:3472-3473. 1989
New chiral auxiliaries for thermal cycloadditions. 111:9238-9240. 1989
Sequence-selective hydrolysis of duplex DNA by an oligonucleotide-directed nuclease. 111:8523-8525. 1989
Stereospecific hydrolysis of alkyl esters by antibodies. 111:5961-5962. 1989
Studies of protein hydration in aqueous-solution by direct NMR observation of individual protein-bound water-molecules. 111:1871-1875. 1989
Synthesis and characterization of the "chiral wall" porphyrin: a chemically robust ligand for metal-catalyzed asymmetric epoxidations. 111:9116-9117. 1989
Synthesis of the abc ring-system of brevetoxin-b. 111:6666-6675. 1989
Synthesis of the brevetoxin-b ijk ring-system. 111:6682-6690. 1989
Synthesis of the fg ring-system of brevetoxin-b. 111:6676-6682. 1989
Synthetic studies on the dioxepane region of brevetoxin-b - new synthetic technology for the construction of oxepanes and synthesis of a model for the cdef ring skeleton of brevetoxin-b. 111:4136-4137. 1989
Total synthesis and evaluation of (+/-)-N-(tert-butyloxycarbonyl)-CBI, (+/-)-CBI-CDPI1, and (+/-)-CBI-CDPI2 - CC-1065 functional agents incorporating the equivalent 1,2,9,9a-tetrahydrocycloprop 1,2-c benz 1,2-e indol-4-one (CBI) left-hand subunit. 111:6461-6463. 1989
Use of a recombinant bacterial fructose-1,6-diphosphate aldolase in aldol reactions - preparative syntheses of 1-deoxynojirimycin, 1-deoxymannojirimycin, 1,4-dideoxy-1,4-imino-d-arabinitol, and fagomine. 111:3924-3927. 1989
A hybrid sequence-selective ribonuclease S. 110:6592-6594. 1988
A new class of chelating agents. 110:5192-5193. 1988
A practical and enantioselective synthesis of glycosphingolipids and related-compounds - total synthesis of globotriaosylceramide (gb3). 110:7910-7912. 1988
A search for peptide ligase: cosolvent-mediated conversion of proteases to esterases for irreversible synthesis of peptides. 110:5162-5166. 1988
Allosteric cooperativity and transport: studies in a circulating system. 110:7140-7143. 1988
Aluminum dichloride and dibromide - preparation, spectroscopic (including matrix-isolation) study, reactions, and role (together with alkyl(aryl)aluminum monohalides) in the preparation of organo-aluminum compounds. 110:3231-3238. 1988
An antibody-catalyzed Claisen rearrangement. 110:4841-4842. 1988
Antibody catalysis approaching the activity of enzymes. 110:2282-2286. 1988
Antibody catalysis in reverse micelles. 110:8713-8714. 1988
Antibody catalysis of bimolecular amide formation. 110:4835-4837. 1988
Asymmetric dihydroxylation via ligand-accelerated catalysis. 110:1968-1970. 1988
Broken symmetry analysis of spin coupling in iron sulfur clusters. 110:1001-1005. 1988
Chemistry of amphotericin-b - degradation studies and preparation of amphoteronolide-b. 110:4660-4672. 1988
Clean tocsy for h-1 spin system-identification in macromolecules. 110:7870-7872. 1988
Convergent functional groups. 5. Ternary complexes in the molecular recognition of beta-arylethylamines. 110:923-927. 1988
Convergent functional groups: catalysis of hemiacetal cleavage in a synthetic molecular cleft. 110:983-984. 1988
Cyclic conjugated enediynes related to calicheamicins and esperamicins - calculations, synthesis, and properties. 110:4866-4868. 1988
DNA cleavage by a synthetic mimic of the calicheamicin esperamicin class of antibiotics. 110:7247-7248. 1988
Enzymes in carbohydrate synthesis - n-acetylneuraminic acid aldolase catalyzed-reactions and preparation of n-acetyl-2-deoxy-d-neuraminic acid-derivatives. 110:6481-6486. 1988
Heteronuclear filters for two-dimensional h-1-NMR - identification of the metal-bound amino-acids in metallothionein and observation of small heteronuclear long-range couplings. 110:2388-2393. 1988
Lipase-catalyzed irreversible transesterifications using enol esters as acylating reagents - preparative enantioselective and regioselective syntheses of alcohols, glycerol derivatives, sugars, and organometallics. 110:7200-7205. 1988
Modification of proteases to esterases for peptide-synthesis - methylchymotrypsin. 110:3709-3710. 1988
Molecular recognition: hydrogen bonding and aromatic stacking converge to bind cytosine derivatives. 110:3327-3328. 1988
Molecular recognition: multipoint contacts with new sizes and shapes. 110:6575-6577. 1988
N,N'-dibenzyl-N,N'-ethylenetartramide: a rationally designed chiral auxiliary for the allylboration reaction. 110:3979-3982. 1988
Novel chemistry of dithiatopazine. 110:4868-4869. 1988
Photosensitized cleavage of a thymine dimer by an antibody. 110:7888-7890. 1988
Site-selective cleavage of RNA by a hybrid enzyme. 110:1614-1615. 1988
Stereoelectronic effects and the active site of the serine proteases. 110:5908-5909. 1988
Total synthesis of (+)-CC-1065 and ent-(-)-CC-1065. 110:1321-1323. 1988
Total synthesis of (+/-)-n-2-(phenylsulfonyl)-cpi, (+/-)-cc-1065, (+)-cc-1065, ent-(-)-cc-1065, and the precise, functional agents (+/-)-cpi-cdpi2, (+)-cpi-cdpi2, and (-)-cpi-cdpi2 (+/-)-(3br-star,4as-star)-deoxy-cc-1065, (+)-(3br,4as)-deoxy-cc-1065, and (-)-(3bs,4ar)-deoxy-cc-1065. 110:4796-4807. 1988
Total synthesis of amphotericin-b .3. The final stages. 110:4696-4705. 1988
Total synthesis of amphoteronolide-b and amphotericin-b .1. Strategy and stereocontrolled construction of key building-blocks. 110:4672-4685. 1988
Total synthesis of amphoteronolide-b and amphotericin-b .2. Total synthesis of amphoteronolide-b. 110:4685-4696. 1988
Total synthesis of linear polyprenoids .3. Syntheses of ubiquinones via palladium-catalyzed oligomerization of monoterpene monomers. 110:4356-4362. 1988
Vicinal diol cyclic sulfates - like epoxides only more reactive. 110:7538-7539. 1988
A highly stereoselective total synthesis of the natural enantiomer of olivin. 109:7575-7577. 1987
Applications of tartrate ester modified allylic boronates in organic-synthesis: an efficient, highly stereoselective synthesis of the C19-C29 segment of rifamycin S. 109:953-955. 1987
Catalytic antibodies. 109:2174-2176. 1987
Catalytic asymmetric epoxidation and kinetic resolution - modified procedures including insitu derivatization. 109:5765-5780. 1987
Convergent functional groups. 3. A molecular cleft recognizes substrates of complementary size, shape, and functionality. 109:2426-2431. 1987
Convergent functional groups. 4. Recognition and transport of amino acids across a liquid membrane. 109:2432-2434. 1987
Diels-alder reactions of heterocyclic azadienes - total synthesis of pde-i, pde-ii, and pde-i dimer methyl-ester. 109:2717-2727. 1987
Dithiatopazine - the 1st stable 1,2-dithietane. 109:3801-3802. 1987
Inhibition of the hydrolysis of para-(dimethylamino)benzoyl fluoride by potassium fluoride. 109:3160-3161. 1987
Kinetic-studies on 1-1 electron-transfer reactions involving blue copper proteins .15. The reactivity of anabaena-variabilis plastocyanin with inorganic complexes and related NMR-studies. 109:6443-6449. 1987
Molecular recognition: Watson-Crick, Hoogsteen, and bifurcated hydrogen bonding in a model for adenine recognition. 109:6866-6867. 1987
Molecular recognition: hydrogen bonding and stacking interactions stabilize a model for nucleic acid structure. 109:5033-5035. 1987
Molecular recognition: new shapes for asymmetric microenvironments. 109:4119-4120. 1987
Molecular recognition: size and shape specificity in the binding of dicarboxylic acids. 109:3474-3475. 1987
Nucleophilic additions to thionolactones - new synthetic technology for the construction of medium-ring and large-ring ethers. 109:2504-2506. 1987
Protein-structure and interactions by combined use of sequential NMR assignments and isotope labeling. 109:1090-1092. 1987
Resonance raman-spectra of the 2fe-2s clusters of the rieske protein from thermus and phthalate dioxygenase from pseudomonas. 109:1559-1561. 1987
Site-selective observation of nuclear overhauser effects in proteins via isotopic labeling. 109:1591-1593. 1987
Stereocontrolled construction of key building-blocks for the total synthesis of amphoteronolide-b and amphotericin-b. 109:2205-2208. 1987
Total synthesis of amphotericin-b. 109:2821-2822. 1987
Total synthesis of amphoteronolide-b. 109:2208-2210. 1987
Triphenylsilyl perchlorate revisited: silicon-29 and chlorine-35 NMR spectroscopy and x-ray crystallography showing covalent nature in both solution and the solid state. Difficulties in observing long-lived silyl cations in the condensed state. 109:5123-5126. 1987
Unexpected diversity in the coordination chemistry of tartrate esters with titanium(iv). 109:1279-1282. 1987
Bridging of macrocycles to bicycles - new synthetic technology for the construction of cis-fused and trans-fused oxopolycyclic systems. 108:6800-6802. 1986
C-C activation of organic small ring compounds by rearrangement of cycloalkylhydridorhodium complexes to rhodacycloalkanes - synthesis of metallacyclobutanes, including one with a tertiary M-C bond, by nucleophilic-addition to p-allyl complexes. 108:7346-7355. 1986
Chemo-, regio-, and diastereoselective alkylation via Lewis acid promoted substitutions of sulfones. 108:1098-1100. 1986
Combined chemical and enzymatic-synthesis of sialyloligosaccharides and characterization by 500-mhz h-1 and c-13 NMR-spectroscopy. 108:2068-2080. 1986
Convergent functional groups provide a measure of stereoelectronic effects at carboxyl oxygen. 108:6068-6069. 1986
Diisopropyl tartrate modified (E)-crotylboronates: highly enantioselective propionate (E)-enolate equivalents. 108:294-296. 1986
Enzymatic aldol condensation isomerization as a route to unusual sugar-derivatives. 108:7812-7818. 1986
Enzyme-catalyzed regioselective deacylation of protected sugars in carbohydrate synthesis. 108:6421-6422. 1986
Highly chemoselective palladium-catalyzed conjugate reduction of alpha,beta-unsaturated carbonyl-compounds with silicon hydrides and zinc-chloride cocatalyst. 108:7314-7325. 1986
Isomerization of the hydridoalkylrhodium complexes formed on oxidative addition of rhodium to alkane C-H bonds - evidence for the intermediacy of h-2-alkane complexes. 108:7332-7346. 1986
Molecular recognition: ionic and aromatic stacking interactions bind complementary functional groups in a molecular cleft. 108:5637-5638. 1986
Multiple-quantum-filtered two-dimensional correlated NMR-spectroscopy of proteins. 108:6482-6492. 1986
New synthetic technology for the construction of oxocenes. 108:2468-2469. 1986
Organic-synthesis with enzymes .3. Tbadh-catalyzed reduction of chloro ketones - total synthesis of (+)-(s,s)-(cis-6-methyltetrahydropyran-2-yl)acetic acid - a civet constituent. 108:3474-3480. 1986
Oxygenation of styrene by cytochrome-p-450 model system - a mechanistic study. 108:2588-2594. 1986
Regioselective phosphoranylation and cyclodehydration of triols with diethoxytriphenylphosphorane. 108:7681-7685. 1986
Simplification of two-dimensional h-1-NMR spectra using an x-filter. 108:6162-6167. 1986
Slow complexation rates of crown ethers: what's taking so long?. 108:5011-5012. 1986
Stereochemistry of the reactions of substituted allylboronates with chiral aldehydes: factors influencing aldehyde diastereofacial selectivity. 108:3422-3434. 1986
Stereospecific 1,2-migrations in carbohydrates - stereocontrolled synthesis of alpha-2-deoxyglycoside beta-2-deoxyglycoside. 108:2466-2467. 1986
Thermal-reactions of cyclopropenone ketals - application of the cycloaddition reactions of delocalized singlet vinylcarbenes - 3-carbon 1,1-dipoles 1,3-dipoles - an alternative synthesis of deacetamidocolchiceine - formal total synthesis of colchicine. 108:6713-6719. 1986
Thermal-reactions of cyclopropenone ketals - key mechanistic features and scope of the cycloaddition reactions of delocalized singlet vinylcarbenes - 3-carbon 1,1-dipoles 1,3-dipoles. 108:6695-6713. 1986
Thermostable enzymes in organic-synthesis .2. Asymmetric reduction of ketones with alcohol-dehydrogenase from thermoanaerobium-brockii. 108:162-169. 1986
Allosteric effects in organic chemistry: binding cooperativity in a model for subunit interactions. 107:7481-7487. 1985
Binding forces and catalysis. The use of bipyridyl-metal chelation to enhance reaction rates. 107:7487-7493. 1985
Convergent functional groups: synthetic and structural studies. 107:7476-7481. 1985
Diastereoselective and enantioselective aldehyde addition-reactions of 2-allyl-1,3,2-dioxaborolane-4,5-dicarboxylic esters, a useful class of tartrate ester modified allylboronates. 107:8186-8190. 1985
Diethoxytriphenylphosphorane: a mild, regioselective cyclodehydrating reagent for conversion of diols to cyclic ethers. Stereochemistry, synthetic utility, and scope. 107:5210-5219. 1985
Enzymatic vs fermentative synthesis - thermostable glucose-dehydrogenase catalyzed regeneration of nad(p)h for use in enzymatic-synthesis. 107:4028-4031. 1985
Enzymatic-synthesis of unusual sugars - galactose-oxidase catalyzed stereospecific oxidation of polyols. 107:2997-2999. 1985
Epoxidation of olefins by cytochrome-p-450 model compounds - kinetics and stereochemistry of oxygen atom transfer and origin of shape selectivity. 107:2000-2005. 1985
Exchange of 2-spin order in nuclear magnetic-resonance - separation of exchange and cross-relaxation processes. 107:6440-6446. 1985
Inverse electron demand Diels-Alder reactions of heterocyclic azadienes - formal total synthesis of streptonigrin. 107:5745-5754. 1985
Mechanism of oxygen atom transfer from high valent iron porphyrins to olefins - implications to the biological epoxidation of olefins by cytochrome-p-450. 107:4343-4345. 1985
Models for ferredoxins: electronic structures of iron-sulfur clusters with one, two, and four iron atoms. 107:3418-3426. 1985
Molecular recognition: three-point binding leads to a selective receptor for aromatic amino acids. 107:6738-6739. 1985
Polypeptide metal cluster connectivities in metallothionein-2 by novel h-1-cd-113 heteronuclear two-dimensional NMR experiments. 107:6847-6851. 1985
Steady-state kinetic-studies of superoxide dismutases - properties of the iron containing protein from escherichia-coli. 107:3295-3304. 1985
Stereocontrolled total synthesis of lipoxins-a. 107:7515-7518. 1985
Stereospecific synthesis of rhynchosporosides - a family of fungal metabolites causing scald disease in barley and other grasses. 107:5556-5558. 1985
Synthetic receptors: size and shape-recognition within a molecular cleft. 107:6736-6738. 1985
Total synthesis of elfamycins - aurodox and efrotomycin .1. Strategy and construction of key intermediates. 107:1691-1694. 1985
Total synthesis of elfamycins - aurodox and efrotomycin .2. Coupling of key intermediates and completion of the synthesis. 107:1695-1698. 1985
Trichothecene metabolism studies: isolation and structure determination of 15-acetyl-3α-(1'β-D-glucopyranosiduronyl)scirpen-3,4β,15-triol. 107:3354-3355. 1985
A general and stereocontrolled total synthesis of leukotriene-b4 and analogs. 106:3548-3551. 1984
Crystal-structures of 2 titanium tartrate asymmetric epoxidation catalysts. 106:6430-6431. 1984
Effective, thermal 3-carbon + 2-carbon cycloaddition for cyclopentenone formation - formal 1,3-dipolar cycloaddition of cyclopropenone ketals. 106:805-807. 1984
Electronic structure, magnetic properties, ESR, and optical spectra for 2-Fe ferredoxin models by LCAO-X alpha valence bond theory. 106:2316-2327. 1984
Epoxidations with selective peracids. 106:1170-1171. 1984
Practical synthesis of oligosaccharides - partial synthesis of avermectin-b1a. 106:4189-4192. 1984
Rapid intramolecular rearrangement of a hydridocyclopropylrhodium complex to a rhodacyclobutane - independent synthesis of the metallacycle by addition of hydride to the central carbon-atom of a cationic rhodium p-allyl complex. 106:7272-7273. 1984
Sulfones as chemical chameleons. Cyclization via 1,1-dipole synthons. 106:7260-7261. 1984
Synthesis of ergot alkaloids from tryptophan. 106:1813-1819. 1984
Total synthesis of (-)-ptilocaulin. 106:721-723. 1984
Total synthesis of 5(s),15(s)-dihydroxy-6,13-trans-8,11-cis-eicosatetraenoic acid (5,15-dihete) and 8(s),15(s)-dihydroxy-5,11-cis-9,13-trans-eicosatetraenoic acid (8,15-dihete) - 2 novel metabolites of arachidonic-acid. 106:5734-5736. 1984
A mild and general-method for the synthesis of o-glycosides. 105:2430-2434. 1983
Allosteric effects: an on-off switch. 105:6668-6670. 1983
Allosteric effects: structural and thermodynamic origins of binding in cooperativity in a subunit model. 105:6759-6760. 1983
Enzyme-catalyzed organic-synthesis - regeneration of deuterated nicotinamide cofactors for use in large-scale enzymatic-synthesis of deuterated substances. 105:5012-5014. 1983
Hydrogen-bond length and h-1-NMR chemical-shifts in proteins. 105:5948-5949. 1983
Preparation of a mixture of nucleoside triphosphates from yeast rna - use in enzymatic-synthesis requiring nucleoside triphosphate regeneration and conversion to nucleoside diphosphate sugars. 105:115-117. 1983
Resonance raman-spectroscopic evidence for a common 3fe-4s structure among proteins containing 3-iron centers. 105:6671-6678. 1983
Sequence-specific double-strand cleavage of DNA by bis(EDTA-distamycin.Fe(II) ) and EDTA-bis(distamycin).Fe(II). 105:7748-7750. 1983
Sequential assignments for the h-1 and p-31 atoms in the backbone of oligonucleotides by two-dimensional nuclear magnetic-resonance. 105:1652-1653. 1983
The mechanism of fe-edta catalyzed superoxide dismutation. 105:5290-5300. 1983
Total synthesis of (+/-)-verrucarol. 105:1058-1060. 1983
Carbohydrates in organic-synthesis - synthesis of 16-membered-ring macrolide antibiotics .5. Total synthesis of o-mycinosyltylonolide - synthesis of key intermediates. 104:2027-2029. 1982
Carbohydrates in organic-synthesis - synthesis of 16-membered-ring macrolide antibiotics .6. Total synthesis of o-mycinosyltylonolide - coupling of key intermediates and macrocyclization. 104:2030-2031. 1982
Design and synthesis of a sequence-specific DNA cleaving molecule. (Distamycin-EDTA)iron(II). 104:6861-6863. 1982
Direct studies of 1,1-diazenes. Syntheses, infrared and electronic spectra, and kinetics of the thermal decomposition of N-(2,2,6,6-tetramethylpiperidyl)nitrene and N-(2,2,5,5-tetramethylpyrrolidyl)nitrene. 104:766-773. 1982
Enzyme-catalyzed transhydrogenation between nicotinamide cofactors and its application in organic-synthesis. 104:3542-3544. 1982
General-method for determining absolute-configurations of acyclic allylic alcohols. 104:3775-3776. 1982
Photochemistry of 1,1-diazenes. Direct and sensitized photolyses of N-(2,2,5,5-tetramethylpyrrolidyl)nitrene, dl-N-(2,5-diethyl-2,5-dimethylpyrrolidyl)nitrene, and N-(2,2,6,6-tetramethylpiperidyl)nitrene. 104:6660-6668. 1982
Soret-excited resonance raman-spectrum of (carbon monoxy)leghemoglobin - assignment of nu-fe-co. 104:626-627. 1982
Stereochemical aspects of the intramolecular Diels-Alder reactions of deca-2,7,9-trienoate esters. 3. Thermal, Lewis acid-catalyzed, and asymmetric cyclizations. 104:2269-2283. 1982
Synthesis of saccharides and related polyhydroxylated natural-products .3. Efficient conversion of 2,3-erythro-aldoses to 2,3-threo-aldoses. 104:3515-3516. 1982
Synthesis of saccharides and related polyhydroxylated natural-products .4. Alpha-d-c-glycopyranoside and beta-d-c-glycopyranoside (2,6-dialkyl-substituted tetrahydropyrans). 104:6468-6470. 1982
The endiandric acid cascade - electrocyclizations in organic-synthesis .1. Stepwise, stereocontrolled total synthesis of endiandric acid-a and acid-b. 104:5555-5557. 1982
The endiandric acid cascade - electrocyclizations in organic-synthesis .2. Stepwise, stereocontrolled total synthesis of endiandric acids-c-acid-g. 104:5557-5558. 1982
The endiandric acid cascade - electrocyclizations in organic-synthesis .3. Biomimetic approach to endiandric acids-a-acid-g - synthesis of precursors. 104:5558-5560. 1982
The endiandric acid cascade - electrocyclizations in organic-synthesis .4. Biomimetic approach to endiandric acids-a-acid-g - total synthesis and thermal studies. 104:5560-5562. 1982
The mechanism of specific acylation of the active-site of alpha-chymotrypsin by n-acylimidazoles. 104:3569-3576. 1982
Asymmetric epoxidation provides shortest routes to 4 chiral epoxy alcohols which are key intermediates in syntheses of methymycin, erythromycin, leukotriene c-1, and disparlure. 103:464-465. 1981
Buildup rates of the nuclear overhauser effect measured by two-dimensional proton magnetic-resonance spectroscopy - implications for studies of protein conformation. 103:3654-3658. 1981
Enzyme-catalyzed organic-synthesis - nad(p)h cofactor regeneration by using glucose-6-phosphate and the glucose-6-phosphate-dehydrogenase from leuconostoc-mesenteroides. 103:4890-4899. 1981
Enzyme-catalyzed organic-synthesis - nad(p)h regeneration using dihydrogen and the hydrogenase from methanobacterium-thermoautotrophicum. 103:6227-6228. 1981
Epoxy alcohol rearrangements - hydroxyl-mediated delivery of lewis acid promoters. 103:462-464. 1981
Intramolecular Diels-Alder reactions: the angularly methylated trans-perhydroindan ring system. 103:6696-6704. 1981
Kinetic resolution of racemic allylic alcohols by enantioselective epoxidation - a route to substances of absolute enantiomeric purity. 103:6237-6240. 1981
Magnetic studies and the crystal and molecular-structure of enh2 v(hedta-h) 2.2h2o - a novel di-mu-alcoxy-bridged dimer of 7-coordinate v(iii). 103:5511-5517. 1981
Organoselenium-based synthesis of oxygen-containing prostacyclins. 103:3480-3485. 1981
Organoselenium-based synthesis of sulfur-containing prostacyclins. 103:3486-3497. 1981
Photochemistry of a 1,1-diazene, N-(2,2,5,5-tetramethylpyrrolidinyl)nitrene. 103:1563-1564. 1981
Studies on the total synthesis of chlorothricolide: stereochemical aspects of the intramolecular Diels-Alder reactions of methyl undeca-2,8,10-trienoates. 103:5200-5211. 1981
Synthesis of (5z)-6,9-thiaprostacyclins and (5e)-6,9-thiaprostacyclins. 103:3472-3480. 1981
Synthesis of 16-membered-ring macrolide antibiotics .3. Carbomycin-b and leucomycin-a3 - retrosynthetic studies. 103:1222-1224. 1981
Synthesis of 16-membered-ring marcolide antibiotics .4. Carbomycin-b and leucomycin-a3 - total synthesis of cyclic key intermediate. 103:1224-1226. 1981
Total synthesis of ionophore antibiotic x-14547a .1. Enantioselective synthesis of the tetrahydropyran and tetrahydroindan building-blocks. 103:6967-6969. 1981
Total synthesis of ionophore antibiotic x-14547a .2. Coupling of the tetrahydropyran and tetrahydroindan systems and construction of the butadienyl and ketopyrrole moieties. 103:6969-6971. 1981
Allosteric effects. Remote control of ion transport selectivity. 102:4853-4854. 1980
Asymmetric induction in the reaction of osmium-tetroxide with olefins. 102:4263-4265. 1980
Carbocyclic thromboxane-a2. 102:1404-1409. 1980
Does substrate rather than protein provide the catalyst for alpha-proton abstraction in aldolase. 102:3923-3927. 1980
Electronic structure of 2-Fe ferredoxin models by X alpha valence bond theory. 102:4279-4282. 1980
Olefin epoxidation with alpha-substituted hydroperoxides. 102:5602-5605. 1980
On binding in subunit systems. 102:7398-7400. 1980
Phenylselenoetherification - a highly efficient cyclization process for the synthesis of o-heterocycles and s-heterocycles. 102:3784-3793. 1980
Practical enzymatic syntheses of ribulose 1,5-bisphosphate and ribose 5-phosphate. 102:7938-7939. 1980
Synthesis and direct spectroscopic observation of N-(2,2,5,5-tetramethylpyrrolidyl)nitrene: comparison of 5-membered and 6-membered cyclic 1,1-dialkyldiazenes. 102:878-880. 1980
The first practical method for asymmetric epoxidation. 102:5974-5976. 1980
Total synthesis of (+/-)-dendrobine. 102:1390-1404. 1980
Total synthesis of (+/-)-zoapatanol. 102:6611-6612. 1980
Total synthesis of rugulovasines. 102:5426-5427. 1980
6,9-pyridazaprostacyclin and derivatives: the first "aromatic" prostacyclins. 101:766-768. 1979
Allosteric effects in organic chemistry. Site-specific binding. 101:4333-4337. 1979
On the rate of site-site interactions in functionalized polystyrenes. 101:737. 1979
Phenylselenolactonization and phenylsulfenolactonization - 2 highly efficient and synthetically useful cyclization procedures. 101:3884-3892. 1979
Selective naked-cluster cryophotochemistry and SCF-X alpha-SW calculations for Cu2 and Ag2. 101:3504-3511. 1979
Chemistry of singlet oxygen. 29. A specific three-phase "Kautsky test" for singlet oxygen. 100:7770-7771. 1978
Dynamics of tautomerization of formycin. 100:3957-3958. 1978
On binding to transition states and ground states: remote catalysis. 100:4315-4316. 1978
Organoselenium-induced ring closures - sulfur-containing prostacyclins - stereoselective synthesis of cyclic alpha,beta-unsaturated sulfoxides, sulfones, and sulfides and synthesis of 6,9-sulfoxa-5(e)-and-5(z)-prostacyclin, 6,9-sulfo-5(e)-and-5(z)-prostacyclin, 6,9-sulfo-6alpha-and-6beta-4(e)-isoprostacyclin, and 6,9-thiaprostacycline. 100:2567-2570. 1978
Osmium-catalyzed vicinal oxyamination of olefins by n-chloro-n-argentocarbamates. 100:3596-3598. 1978
Steric steering with supported palladium catalysts. 100:7779-7781. 1978
The first d0 metallooxaziridines. Amination of olefins. 100:7061-7063. 1978
The three-phase test: intermediates in phosphate transfer reactions. 100:8113-8117. 1978
Total synthesis of (+/-)-dendrobine. 100:3599-3601. 1978
Total synthesis of erythromycins .3. Stereoselective routes to intermediates corresponding to c(1) to c(9) and c(10) to c(13) fragments of erythronolide-b. 100:4618-4620. 1978
Total synthesis of erythromycins .4. Total synthesis of erythronolide-b. 100:4620-4622. 1978
Transient proton-proton overhauser effects in horse ferrocytochrome-c. 100:7094-7096. 1978
6,9-thiaprostacyclin. A stable and biologically potent analogue of prostacyclin (PGI2). 99:7736-7738. 1977
Allylic oxidation of olefins by catalytic and stoichiometric selenium dioxide with tert-butyl hydroperoxide. 99:5526-5528. 1977
Catalysis of superoxide dismutation by iron-ethylenediaminetetraacetic acid complexes - mechanism of reaction and evidence for direct formation of an iron(iii)-ethylenediaminetetraacetic acid peroxo complex from reaction of superoxide with "iron(ii)-ethylenediaminetetraacetic acid. 99:5220-5222. 1977
Chiral hydroxamic acids as ligands in vanadium catalyzed asymmetric epoxidation of allylic alcohols by tert-butyl hydroperoxide. 99:1990-1992. 1977
Chromyl chloride oxidations of olefins - possible role of organometallic intermediates in oxidations of olefins by oxo transition-metal species. 99:3120-3128. 1977
Organic chemistry on the solid phase. Site-site interactions on functionalized polystyrene. 99:625-626. 1977
Phenylselenolactonization - extremely mild and synthetically useful cyclization process. 99:3185-3187. 1977
Synthesis of dioxobis(tert-alkylimido)osmium(viii) and oxotris(tert-alkylimido)osmium(viii) complexes - stereospecific vicinal diamination of olefins. 99:3420-3426. 1977
Allylic amination of olefins and acetylenes by imido selenium-compounds. 98:269-271. 1976
Osmium catalyzed vicinal hydroxylation of olefins by tert-butyl hydroperoxide under alkaline conditions. 98:1986-1987. 1976
Selenium dioxide oxidation of ketones and aldehydes - evidence for intermediacy of beta-ketoseleninic acids. 98:300-301. 1976
Kinetics and equilibria of reaction of pyridoxal 5'-phosphate with ethylenediamine to form schiff-bases and cyclic geminal diamines - evidence for kinetically competent geminal diamine intermediates in transimination sequences. 97:6530-6539. 1975
New probes for the study of acylation reactions. 97:4407-4408. 1975
Oxidation of alcohols to aldehydes by reagents derived from chromyl chloride. 97:5927-5928. 1975
The three phase test for reaction intermediates. Evidence for monomeric metaphosphate. 97:3221-3222. 1975
The three-phase test for reaction intermediates. Metaphosphates. 97:1591-1592. 1975
The three-phase test for reaction intermediates. Nucleophilic catalysis and elimination reactions. 97:454-455. 1975
Three-phase test. Detection of free cyclobutadiene. 97:3453-3456. 1975
Efficient and mild lactonization method for synthesis of macrolides. 96:5614-5616. 1974
Intermolecular proton-transfer reaction between base and phosphate moieties of mononucleotides in solution. 96:2609-2611. 1974
Mechanism of the carbodiimide reaction. II. Peptide synthesis on the solid phase. 96:1606-1607. 1974
The three-phase test for reactive intermediates. Cyclobutadiene. 96:7112-7114. 1974
An improved method for the study of reaction intermediates. The mechanism of peptide synthesis mediated by carbodiimides. 95:4052-4053. 1973
Diastereomeric monocyclic diallenes. Synthesis and properties of the diastereomeric 3,4,9,10-cyclododecatetraene-1,7-diones and 3,4,10,11-cyclotetradecatetraene-1,8-diones. 95:4582-4592. 1973
Electrophilic and nucleophilic organoselenium reagents. New routes to alpha, beta-unsaturated carbonyl compounds. 95:6137-6139. 1973
High stereo- and regioselectivities in the transition metal catalyzed epoxidations of olefinic alcohols by tert-butyl hydroperoxide. 95:6136-6137. 1973
Reorientational correlation-functions obtained from Raman line shapes. 95:1391-1398. 1973
Selenium dioxide oxidations of olefins - trapping of allylic seleninic acid intermediate as a seleninolactone. 95:7917-7919. 1973
Lower valent tungsten halides. New class of reagents for deoxygenation of organic molecules. 94:6538-6540. 1972
Mechanism of epoxidation of olefins by covalent peroxides of molybdenum(vi). 94:295-296. 1972
Selenium dioxide oxidation of olefins. Evidence for intermediacy of allylseleninic acids. 94:7154-7155. 1972
Permanganate in acetic anhydride. Alpha-diketones directly from olefins. 93:3303-3304. 1971
D,l-malabaricanediol. The first cyclic natural product derived from squalene in a nonenzymic process. 92:6999-7001. 1970
Magnetic resonance and mass spectrum of pi-cyclopentadienyl-pi-cycloheptatrienylvanadium. Mass spectral rearrangement to bis(benzene)vanadium. 92:5100-5104. 1970
Peptide racemization mechanism. A kinetic isotope effect as a means of distinguishing enolization from oxazolone formation. 92:5792-5793. 1970
Racemization during peptide couplings using the mixed anhydride, N-hydroxysuccinimide ester, 8-hydroxyquinoline ester, and acyl azide methods. 92:4756-4757. 1970
Mechanism of the titanium-promoted deoxygenative coupling of allyl and benzyl alcohols to hydrocarbons. 91:1552-1554. 1969
Terpene terminal epoxides. Skeletal rearrangement accompanying bicyclization of squalene 2,3-oxide. 91:1848-1849. 1969
Enzymic cyclization of 15-norsqualene 2,3-oxide. 90:3284-3286. 1968
One-step synthesis of 1,5-dienes involving reductive coupling of allyl alcohols. 90:209-210. 1968
An investigation of water-urea and water-urea-polyethylene glycol interactions. 89:442-446. 1967
Biological activities of some terminally modified squalene and squalene 2,3-oxide analogs. 89:3920-3922. 1967
Dipole moments in relation to configuration of polypeptide chains. 89:6807-6813. 1967
Enzymic cyclization of trans,trans,trans-18,19-dehydrosqualene 2,3-oxide. 89:7150-7151. 1967
Equilibrium measurements of the binding of cytidine 3'-phosphate to ribonuclease. 87:4665-4669. 1965
Purification and characterization of sheep prolactin. 83:3717-3719. 1961

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