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Inhibitors of HIV-1 protease by using in situ click chemistry

Academic Article
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Overview

authors

  • Whiting, M.
  • Muldoon, J.
  • Lin, Y. C.
  • Silverman, S. M.
  • Lindstrom, W.
  • Olson, Arthur
  • Kolb, H. C.
  • Finn, M.G.
  • Sharpless, K. Barry
  • Elder, John
  • Fokin, Valery

publication date

  • 2006

journal

  • Angewandte Chemie-International Edition  Journal

subject areas

  • Chromatography, High Pressure Liquid
  • Combinatorial Chemistry Techniques
  • HIV Protease Inhibitors
  • Mass Spectrometry
  • Molecular Conformation
  • Sensitivity and Specificity
  • Stereoisomerism
  • Time Factors
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Research

keywords

  • HIV-1 protease
  • click chemistry
  • drug design
  • inhibitors
  • triazoles
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Identity

International Standard Serial Number (ISSN)

  • 1433-7851

Digital Object Identifier (DOI)

  • 10.1002/anie.200502161

PubMed ID

  • 16425339
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Additional Document Info

start page

  • 1435

end page

  • 1439

volume

  • 45

issue

  • 9

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