Scripps VIVO scripps research logo

  • Index
  • Log in
  • Home
  • People
  • Organizations
  • Research
  • Events
Search form

A deep cavitand provides a structured environment for the menschutkin reaction

Academic Article
uri icon
  • Overview
  • Identity
  • Additional Document Info
  • View All
scroll to property group menus

Overview

related to degree

  • Purse, Byron, Ph.D. in Chemistry, Scripps Research 2000 - 2005

authors

  • Purse, Byron
  • Gissot, A.
  • Rebek Jr., Julius

publication date

  • August 2005

journal

  • Journal of the American Chemical Society  Journal

abstract

  • We report that a synthetic, vase-shaped host molecule forms complexes with quinuclidine and accelerates the Menschutkin reaction in the nanoenvironment that the host provides. Kinetic simulation is used to determine rate constants for reactions of the complex, and these are compared to control reactions in the absence of the host. The efficacy of the host in effecting this supramolecular acceleration is dependent on the structures of the alkylating agent and its leaving group.
scroll to property group menus

Identity

International Standard Serial Number (ISSN)

  • 0002-7863

Digital Object Identifier (DOI)

  • 10.1021/ja052877+

PubMed ID

  • 16089433
scroll to property group menus

Additional Document Info

start page

  • 11222

end page

  • 11223

volume

  • 127

issue

  • 32

©2021 The Scripps Research Institute | Terms of Use | Powered by VIVO

  • About
  • Contact Us
  • Support