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Checkpoints on the road to mitosis

Academic Article
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Overview

authors

  • Russell, Paul

publication date

  • 1998

journal

  • Trends in Biochemical Sciences  Journal

abstract

  • Eukaryotic organisms use cell-cycle checkpoints to ensure that nuclear division is restrained while DNA is undergoing replication or repair. Recent studies of the fission yeast Schizosaccharomyces pombe have illuminated these checkpoint mechanisms. These investigations have connected checkpoint proteins with central elements of the mitotic-control machinery.

subject areas

  • 14-3-3 Proteins
  • Animals
  • DNA Repair
  • DNA Replication
  • Humans
  • Mitosis
  • Models, Biological
  • Phosphates
  • Protein Kinases
  • Proteins
  • Schizosaccharomyces
  • Tyrosine 3-Monooxygenase
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Identity

International Standard Serial Number (ISSN)

  • 0968-0004

Digital Object Identifier (DOI)

  • 10.1016/s0968-0004(98)01291-2

PubMed ID

  • 9810229
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Additional Document Info

start page

  • 399

end page

  • 402

volume

  • 23

issue

  • 10

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