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Unraveling the effect of changes in conformation and compactness at the antibody V(L)-V(H) interface upon antigen binding

Academic Article
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Overview

authors

  • Pellequer, J. L.
  • Chen, S. W. W.
  • Roberts, V. A.
  • Tainer, John
  • Getzoff, Elizabeth

publication date

  • July 1999

journal

  • Journal of Molecular Recognition  Journal

subject areas

  • Antigen-Antibody Reactions
  • Computer Simulation
  • Humans
  • Immunoglobulin Heavy Chains
  • Immunoglobulin Light Chains
  • Immunoglobulin Variable Region
  • Models, Immunological
  • Models, Molecular
  • Protein Binding
  • Protein Conformation
  • Software
  • Thermodynamics
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Research

keywords

  • Fv
  • antigen recognition
  • molecular surface
  • three-dimensional structure
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Identity

International Standard Serial Number (ISSN)

  • 0952-3499

Digital Object Identifier (DOI)

  • 10.1002/(sici)1099-1352(199907/08)12:4<267::aid-jmr465>3.0.co;2-9

PubMed ID

  • 10440998
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Additional Document Info

start page

  • 267

end page

  • 275

volume

  • 12

issue

  • 4

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