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Targeting the autolysis loop of urokinase-type plasminogen activator with conformation-specific monoclonal antibodies

Academic Article
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Overview

authors

  • Botkjaer, K. A.
  • Fogh, S.
  • Bekes, E. C.
  • Chen, Z.
  • Blouse, G. E.
  • Jensen, J. M.
  • Mortensen, K. K.
  • Huang, M. D.
  • Deryugina, Elena
  • Quigley, James
  • Declerck, P. J.
  • Andreasen, P. A.

publication date

  • August 2011

journal

  • Biochemical Journal  Journal

subject areas

  • Animals
  • Antibodies, Monoclonal
  • Autolysis
  • Cell Movement
  • Chick Embryo
  • Enzyme Activation
  • Enzyme Precursors
  • Fibrinolytic Agents
  • Humans
  • Hydrolysis
  • Kinetics
  • Mice
  • Mice, Inbred BALB C
  • Plasminogen
  • Receptors, Urokinase Plasminogen Activator
  • Surface Plasmon Resonance
  • Urokinase-Type Plasminogen Activator
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Research

keywords

  • antibody
  • cancer
  • conformation
  • immunofluorescence
  • urokinase-type plasminogen activator (uPA)
  • zymogen
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Identity

International Standard Serial Number (ISSN)

  • 0264-6021

Digital Object Identifier (DOI)

  • 10.1042/bj20110129

PubMed ID

  • 21635223
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Additional Document Info

start page

  • 39

end page

  • 51

volume

  • 438

issue

  • 1

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