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Insights into the molecular recognition of the 5 '-gnn-3 ' family of DNA sequences by zinc finger domains

Academic Article
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Overview

authors

  • Dreier, B.
  • Segal, D. J.
  • Barbas III, Carlos

publication date

  • November 2000

journal

  • Journal of Molecular Biology  Journal

subject areas

  • Amino Acid Sequence
  • Base Sequence
  • Cloning, Molecular
  • Computer Simulation
  • Crystallography, X-Ray
  • DNA
  • DNA-Binding Proteins
  • Drug Design
  • Histidine
  • Lysine
  • Models, Molecular
  • Molecular Sequence Data
  • Mutation
  • Nuclear Magnetic Resonance, Biomolecular
  • Nucleic Acid Conformation
  • Peptide Library
  • Pliability
  • Protein Engineering
  • Protein Structure, Secondary
  • Substrate Specificity
  • Zinc Fingers
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Research

keywords

  • binding specificity
  • novel DNA-binding proteins
  • phage display selection
  • protein : nucleic acid computer modeling
  • rational design
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Identity

International Standard Serial Number (ISSN)

  • 0022-2836

Digital Object Identifier (DOI)

  • 10.1006/jmbi.2000.4133

PubMed ID

  • 11054286
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Additional Document Info

start page

  • 489

end page

  • 502

volume

  • 303

issue

  • 4

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