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The plasma contact system in atopic asthma

Academic Article
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Overview

authors

  • Lasser, E. C.
  • Lang, J. H.
  • Curd, J. G.
  • Cochrane, Charles
  • Lyon, S. G.
  • Howard, M. M.
  • Hamblin, A. E.
  • Revak, S. D.

publication date

  • 1983

journal

  • Journal of Allergy and Clinical Immunology  Journal

abstract

  • An in vitro test for the rate of appearance of kallikrein in plasma due to contact system activation by dextran sulfate at 0 degree C was applied to plasmas of 19 atopic asthma patients and 19 age- and sex-matched controls without atopy. The average prekallikrein activation rate was markedly higher in the plasmas of the atopic patients. Mean endogenous heparin levels were also elevated.

subject areas

  • Adolescent
  • Adult
  • Asthma
  • Child
  • Child, Preschool
  • Dextran Sulfate
  • Dextrans
  • Factor XII
  • Female
  • Heparin
  • Humans
  • Kallikreins
  • Male
  • Middle Aged
  • Prekallikrein
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Identity

International Standard Serial Number (ISSN)

  • 0091-6749

Digital Object Identifier (DOI)

  • 10.1016/0091-6749(83)90056-8

PubMed ID

  • 6189880
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Additional Document Info

start page

  • 83

end page

  • 88

volume

  • 72

issue

  • 1

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