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Diabetes

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articles

  • Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding.  69:1723-1734. 2020
  • Single-cell analysis of CD4 T cells in type 1 diabetes: from mouse to man, how to perform mechanistic studies.  68:1886-1891. 2019
  • Visualization and quantification of browning using a Ucp1-2A-luciferase knock-in mouse model.  66:407-417. 2017
  • CRISPR-Cas9-Mediated Modification of the NOD Mouse Genome With Ptpn22(R619W) Mutation Increases Autoimmune Diabetes.  65:2134-2138. 2016
  • GLUT4 expression in adipocytes regulates de novo lipogenesis and levels of a novel class of lipids with antidiabetic and anti-inflammatory effects.  65:1808-1815. 2016
  • PPARγ antagonist Gleevec improves insulin sensitivity and promotes the browning of white adipose tissue.  65:829-839. 2016
  • Regulation of substrate oxidation preferences in muscle by the peptide hormone adropin.  63:3242-3252. 2014
  • Identification of a small molecular insulin receptor agonist with potent antidiabetes activity.  63:1394-1409. 2014
  • Exosomes released by islet-derived mesenchymal stem cells trigger autoimmune responses in NOD mice.  63:1008-1020. 2014
  • Inhibition of class i histone deacetylases unveils a mitochondrial signature and enhances oxidative metabolism in skeletal muscle and adipose tissue.  62:732-742. 2013
  • Cellular mechanisms of restored β-cell tolerance mediated by protective alleles of Idd3 and Idd5.  61:166-174. 2012
  • In vivo expression of HGF/NK1 and GLP-1 from dsAAV vectors enhances pancreatic beta-cell proliferation and improves pathology in the db/db mouse model of diabetes.  59:3108-3116. 2010
  • Idd9.2 and Idd9.3 protective alleles function in CD4+ T-cells and nonlymphoid cells to prevent expansion of pathogenic islet-specific CD8+ T-cells.  59:1478-1486. 2010
  • A point mutation in sec61 alpha 1 leads to diabetes and hepatosteatosis in mice.  59:460-470. 2010
  • A recurring problem with the analysis of energy expenditure in genetic models expressing lean and obese phenotypes.  59:323-329. 2010
  • Insulin causes hyperthermia by direct inhibition of warm-sensitive neurons.  59:43-50. 2010
  • Loss-of-function mutation in myostatin reduces tumor necrosis factor alpha production and protects liver against obesity-induced insulin resistance.  58:1133-1143. 2009
  • Slc11a1 enhances the autoimmune diabetogenic T-cell response by altering processing and presentation of pancreatic islet antigens.  58:156-164. 2009
  • Switching-on survival and repair response programs in islet transplants by bone marrow-derived vasculogenic cells.  57:2402-2412. 2008
  • Widespread and stable pancreatic gene transfer by adeno-associated virus vectors via different routes.  55:875-884. 2006
  • Impaired gene and protein expression of exocytotic soluble N-ethylmaleimide attachment protein receptor complex proteins in pancreatic islets of type 2 diabetic patients.  55:435-440. 2006
  • The class I HLA repertoire of pancreatic islets comprises the nonclassical class Ib antigen HLA-G.  55:1214-1222. 2006
  • Resistance to diet-induced obesity in mu-opioid receptor-deficient mice: Evidence for a "thrifty gene".  54:3510-3516. 2005
  • Genome-wide linkage scans for fasting glucose, insulin, and insulin resistance in the national heart, lung, and blood institute family blood pressure program - evidence of linkages to chromosome 7q36 and 19q13 from meta-analysis.  54:909-914. 2005
  • Increased hepatic levels of the insulin receptor inhibitor, PC-1/NPP1, induce insulin resistance and glucose intolerance.  54:367-372. 2005
  • Activated protein C preserves functional islet mass after intraportal transplantation - a novel link between endothelial cell activation, thrombosis, inflammation, and islet cell death.  53:2804-2814. 2004
  • Endurance training in humans leads to fiber type-specific increases in levels of peroxisome proliferator-activated receptor-gamma coactivator-1 and peroxisome proliferator-activated receptor-alpha in skeletal muscle.  52:2874-2881. 2003
  • Prevention of diabetes in NOD nice by administration of dendritic cells deficient in nuclear transcription factor-kappa B activity.  52:1976-1985. 2003
  • The insulin secretory granule is the major site of K(ATP) channels of the endocrine pancreas.  52:767-776. 2003
  • Gene transfer of manganese superoxide dismutase extends islet graft function in a mouse model of autoimmune diabetes.  52:387-393. 2003
  • Indoleamine 2,3-dioxygenase expression in trans-planted NOD islets prolongs graft survival after adoptive transfer of diabetogenic splenocytes.  51:356-365. 2002
  • Suggestive evidence for association of human chromosome 18q12-q21 and its orthologue on rat and mouse chromosome 18 with several autoimmune diseases.  50:184-194. 2001
  • A common promoter variant of the leptin gene is associated with changes in the relationship between serum leptin and fat mass in obese girls.  49:2196-2200. 2000
  • Targeting autoimmune diabetes with gene therapy.  48:2107-2121. 1999
  • Adenoviral gene transfer of the interleukin-1 receptor antagonist protein to human islets prevents IL-1 beta-induced b-cell impairment and activation of islet cell apoptosis in vitro.  48:1730-1736. 1999
  • Mice expressing human but not murine beta-adrenergic receptors under the control of human gene regulatory elements.  47:1464-1471. 1998
  • Perspectives in diabetes - genetic analysis of niddm - the study of quantitative traits.  45:1-14. 1996
  • Crosses of nod mice with the related non strain - a polygenic model for iddm.  44:1186-1195. 1995
  • Plasma apolipoproteins-ai, apolipoprotein-aii, apolipoprotein-b, apolipoprotein-ci, and apolipoprotein-e are glucosylated in hyperglycemic diabetic subjects.  34:452-461. 1985
  • Characterization of the conversion of a somatostatin precursor to somatostatin by islet secretory granules.  29:593-599. 1980
  • Effects of indomethacin on acute insulin release in man.  29:379-382. 1980
  • Diabetic vascular complications in long-standing panhypopituitarism with diabetes. A case report.  15:419-422. 1966
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Identity

International Standard Serial Number (ISSN)

  • 0012-1797

Electronic International Standard Serial Number (EISSN)

  • 1939-327X

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