articles
- Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding. 69:1723-1734. 2020
- Single-cell analysis of CD4 T cells in type 1 diabetes: from mouse to man, how to perform mechanistic studies. 68:1886-1891. 2019
- Visualization and quantification of browning using a Ucp1-2A-luciferase knock-in mouse model. 66:407-417. 2017
- CRISPR-Cas9-Mediated Modification of the NOD Mouse Genome With Ptpn22(R619W) Mutation Increases Autoimmune Diabetes. 65:2134-2138. 2016
- GLUT4 expression in adipocytes regulates de novo lipogenesis and levels of a novel class of lipids with antidiabetic and anti-inflammatory effects. 65:1808-1815. 2016
- PPARγ antagonist Gleevec improves insulin sensitivity and promotes the browning of white adipose tissue. 65:829-839. 2016
- Exosomes released by islet-derived mesenchymal stem cells trigger autoimmune responses in NOD mice. 63:1008-1020. 2014
- Identification of a small molecular insulin receptor agonist with potent antidiabetes activity. 63:1394-1409. 2014
- Regulation of substrate oxidation preferences in muscle by the peptide hormone adropin. 63:3242-3252. 2014
- Inhibition of class i histone deacetylases unveils a mitochondrial signature and enhances oxidative metabolism in skeletal muscle and adipose tissue. 62:732-742. 2013
- Cellular mechanisms of restored β-cell tolerance mediated by protective alleles of Idd3 and Idd5. 61:166-174. 2012
- A point mutation in sec61 alpha 1 leads to diabetes and hepatosteatosis in mice. 59:460-470. 2010
- A recurring problem with the analysis of energy expenditure in genetic models expressing lean and obese phenotypes. 59:323-329. 2010
- Idd9.2 and Idd9.3 protective alleles function in CD4+ T-cells and nonlymphoid cells to prevent expansion of pathogenic islet-specific CD8+ T-cells. 59:1478-1486. 2010
- In vivo expression of HGF/NK1 and GLP-1 from dsAAV vectors enhances pancreatic beta-cell proliferation and improves pathology in the db/db mouse model of diabetes. 59:3108-3116. 2010
- Insulin causes hyperthermia by direct inhibition of warm-sensitive neurons. 59:43-50. 2010
- Loss-of-function mutation in myostatin reduces tumor necrosis factor alpha production and protects liver against obesity-induced insulin resistance. 58:1133-1143. 2009
- Slc11a1 enhances the autoimmune diabetogenic T-cell response by altering processing and presentation of pancreatic islet antigens. 58:156-164. 2009
- Switching-on survival and repair response programs in islet transplants by bone marrow-derived vasculogenic cells. 57:2402-2412. 2008
- Impaired gene and protein expression of exocytotic soluble N-ethylmaleimide attachment protein receptor complex proteins in pancreatic islets of type 2 diabetic patients. 55:435-440. 2006
- The class I HLA repertoire of pancreatic islets comprises the nonclassical class Ib antigen HLA-G. 55:1214-1222. 2006
- Widespread and stable pancreatic gene transfer by adeno-associated virus vectors via different routes. 55:875-884. 2006
- Increased hepatic levels of the insulin receptor inhibitor, PC-1/NPP1, induce insulin resistance and glucose intolerance. 54:367-372. 2005
- Genome-wide linkage scans for fasting glucose, insulin, and insulin resistance in the national heart, lung, and blood institute family blood pressure program - evidence of linkages to chromosome 7q36 and 19q13 from meta-analysis. 54:909-914. 2005
- Resistance to diet-induced obesity in mu-opioid receptor-deficient mice: Evidence for a "thrifty gene". 54:3510-3516. 2005
- Activated protein C preserves functional islet mass after intraportal transplantation - a novel link between endothelial cell activation, thrombosis, inflammation, and islet cell death. 53:2804-2814. 2004
- Endurance training in humans leads to fiber type-specific increases in levels of peroxisome proliferator-activated receptor-gamma coactivator-1 and peroxisome proliferator-activated receptor-alpha in skeletal muscle. 52:2874-2881. 2003
- Gene transfer of manganese superoxide dismutase extends islet graft function in a mouse model of autoimmune diabetes. 52:387-393. 2003
- Prevention of diabetes in NOD nice by administration of dendritic cells deficient in nuclear transcription factor-kappa B activity. 52:1976-1985. 2003
- The insulin secretory granule is the major site of K(ATP) channels of the endocrine pancreas. 52:767-776. 2003
- Indoleamine 2,3-dioxygenase expression in trans-planted NOD islets prolongs graft survival after adoptive transfer of diabetogenic splenocytes. 51:356-365. 2002
- Suggestive evidence for association of human chromosome 18q12-q21 and its orthologue on rat and mouse chromosome 18 with several autoimmune diseases. 50:184-194. 2001
- A common promoter variant of the leptin gene is associated with changes in the relationship between serum leptin and fat mass in obese girls. 49:2196-2200. 2000
- Adenoviral gene transfer of the interleukin-1 receptor antagonist protein to human islets prevents IL-1 beta-induced b-cell impairment and activation of islet cell apoptosis in vitro. 48:1730-1736. 1999
- Targeting autoimmune diabetes with gene therapy. 48:2107-2121. 1999
- Mice expressing human but not murine beta-adrenergic receptors under the control of human gene regulatory elements. 47:1464-1471. 1998
- Perspectives in diabetes - genetic analysis of niddm - the study of quantitative traits. 45:1-14. 1996
- Crosses of nod mice with the related non strain - a polygenic model for iddm. 44:1186-1195. 1995
- Plasma apolipoproteins-ai, apolipoprotein-aii, apolipoprotein-b, apolipoprotein-ci, and apolipoprotein-e are glucosylated in hyperglycemic diabetic subjects. 34:452-461. 1985
- Characterization of the conversion of a somatostatin precursor to somatostatin by islet secretory granules. 29:593-599. 1980
- Effects of indomethacin on acute insulin release in man. 29:379-382. 1980
- Diabetic vascular complications in long-standing panhypopituitarism with diabetes. A case report. 15:419-422. 1966