recent publications

• academic article

  • Voronov, D., Gromova, A., Liu, D., Zoukhri, D., Medvinsky, A., Meech, R., Makarenkova, H. P. Transcription factors Runx1 to 3 are expressed in the lacrimal gland epithelium and are involved in regulation of gland morphogenesis and regeneration Investigative Ophthalmology and Visual Science  2013 54:3115-3125  DOI:10.1167/iovs.13-11791  PMID:23532528  PMCID:PMC3643397
  • Welburn, J. P. I., Vleugel, M., Liu, D., Yates, J. R., Lampson, M. A., Fukagawa, T., Cheeseman, I. M. Aurora B phosphorylates spatially distinct targets to differentially regulate the kinetochore-microtubule interface Molecular Cell  2010 38:383-392  DOI:10.1016/j.molcel.2010.02.034  PMID:20471944  PMCID:PMC2873218
  • Guo, H., Wang, Y. M., Singh, I., Liu, D., Fernandez, J. A., Griffin, J. H., Chow, N., Zlokovic, B. V. Species-dependent neuroprotection by activated protein C mutants with reduced anticoagulant activity Journal of Neurochemistry  2009 109:116-124  DOI:10.1111/j.1471-4159.2009.05921.x  PMID:19166505  PMCID:PMC2692505
  • Cheng, T., Petraglia, A. L., Li, Z., Thiyagarajan, M., Zhong, Z. H., Wu, Z. H., Liu, D., Maggirwar, S. B., Deane, R., Fernandez, J. A., LaRue, B., Griffin, J. H., et al. Activated protein C inhibits tissue plasminogen activator-induced brain hemorrhage Nature Medicine  2006 12:1278-1285  DOI:10.1038/nm1498  PMID:17072311
  • Griffin, J. H., Fernandez, J. A., Mosnier, L. O., Liu, D., Cheng, T., Guo, H., Zlokovic, B. V. The promise of protein C Blood Cells Molecules and Diseases  2006 36:211-216  DOI:10.1016/j,bcmd.2005.12.023  PMID:16464623
  • Zlokovic, B. V., Zhang, C. L., Liu, D., Fernandez, J., Griffin, J. H., Chopp, M. Functional recovery after embolic stroke in rodents by activated protein C Annals of Neurology  2005 58:474-477  DOI:10.1002/ana.20602  PMID:16130108
  • Liu, D., Cheng, T., Guo, H., Fernandez, J. A., Griffin, J. H., Song, X. M., Zlokovic, B. V. Tissue plasminogen activator neurovascular toxicity is controlled by activated protein C Nature Medicine  2004 10:1379-1383  DOI:10.1038/nm1122  PMID:15516929
  • Griffin, J. H., Fernandez, J. A., Liu, D., Cheng, T., Guo, H., Zlokovic, B. V. Activated protein C and ischemic stroke Critical Care Medicine  2004 32:S247-S253  DOI:10.1097/01.cmm.0000126127.87484.2b  PMID:15118526
  • Guo, H., Liu, D., Gelbard, H., Cheng, T., Insalaco, R., Fernandez, J. A., Griffin, J. H., Zlokovic, B. V. Activated protein C prevents neuronal apoptosis via protease activated receptors 1 and 3 Neuron  2004 41:563-572  DOI:10.1016/s0896-6273(04)00019-4  PMID:14980205
  • Fernandez, J. A., Xu, X., Liu, D., Zlokovic, B. V., Griffin, J. H. Recombinant murine-activated protein C is neuroprotective in a murine ischemic stroke model Blood Cells Molecules and Diseases  2003 30:271-276  DOI:10.1016/s1079-9796(03)00034-2  PMID:12737945
  • Liu, D., Guo, H., Griffin, J. H., Fernandez, J. A., Zlokovic, B. V. Protein S confers neuronal protection during ischemic/hypoxic injury in mice Circulation  2003 107:1791-1796  DOI:10.1161/01.cir.0000058460.34453.5a  PMID:12665496
  • Cheng, T., Liu, D., Griffin, J. H., Fernandez, J. A., Castellino, F., Rosen, E. D., Fukudome, K., Zlokovic, B. V. Activated protein c blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective Nature Medicine  2003 9:338-342  DOI:10.1038/nm826  PMID:12563316