recent publications

• academic article

  • Alt, J. R., Greiner, T. C., Cleveland, J. L., Eischen, C. M. Mdm2 haplo-insufficiency profoundly inhibits myc-induced lymphomagenesis EMBO Journal  2003 22:1442-1450  DOI:10.1093/emboj/cdg133  PMID:12628936  PMCID:PMC151074
  • Eischen, C. M., Rehg, J. E., Korsmeyer, S. J., Cleveland, J. L. Loss of bax alters tumor spectrum and tumor numbers in arf-deficient mice Cancer Research  2002 62:2184-2191  PMID:11929842
  • Eischen, C. M., Woo, D., Roussel, M. F., Cleveland, J. L. Apoptosis triggered by myc-induced suppression of bcl-x-l or bcl-2 is bypassed during lymphomagenesis Molecular and Cellular Biology  2001 21:5063-5070  DOI:10.1128/mcb.21.15.5063-5070.2001  PMID:11438662
  • Braun, J. S., Novak, R., Murray, P. J., Eischen, C. M., Susin, S. A., Kroemer, G., Halle, A., Weber, J. R., Tuomanen, E. I., Cleveland, J. L. Apoptosis-inducing factor mediates microglial and neuronal apoptosis caused by pneumococcus Journal of Infectious Diseases  2001 184:1300-1309  DOI:10.1086/324013  PMID:11679919
  • Eischen, C. M., Roussel, M. F., Korsmeyer, S. J., Cleveland, J. L. Bax loss impairs myc-induced apoptosis and circumvents the selection of p53 mutations during myc-mediated lymphomagenesis Molecular and Cellular Biology  2001 21:7653-7662  DOI:10.1128/mcb.21.22.7653-7662.2001  PMID:11604501
  • Eischen, C. M., Packham, G., Nip, J., Fee, B. E., Hiebert, S. W., Zambetti, G. P., Cleveland, J. L. Bcl-2 is an apoptotic target suppressed by both c-myc and e2f-1 Oncogene  2001 20:6983-6993  DOI:10.1038/sj.onc.1204892  PMID:11704823
  • Nip, J., Strom, D. K., Eischen, C. M., Cleveland, J. L., Zambetti, G. P., Hiebert, S. W. E2f-1 induces the stabilization of p53 but blocks p53-mediated transactivation Oncogene  2001 20:910-920  DOI:10.1038/sj.onc.1204171  PMID:11314026
  • Eischen, C. M., Weber, J. D., Roussel, M. F., Sherr, C. J., Cleveland, J. L. Disruption of the arf-mdm2-p53 tumor suppressor pathway in myc-induced lymphomagenesis Genes & Development  1999 13:2658-2669  DOI:10.1101/gad.13.20.2658  PMID:10541552  PMCID:PMC317106
  • Zindy, F., Eischen, C. M., Randle, D. H., Kamijo, T., Cleveland, J. L., Sherr, C. J., Roussel, M. F. Myc signaling via the arf tumor suppressor regulates p53-dependent apoptosis and immortalization Genes & Development  1998 12:2424-2433  DOI:10.1101/gad.12.15.2424  PMID:9694806  PMCID:PMC317045
  • Packham, G., White, E. L., Eischen, C. M., Yang, H., Parganas, E., Ihle, J. N., Grillot, D. A. M., Zambetti, G. P., Nunez, G., Cleveland, J. L. Selective regulation of bcl-xl by a jak kinase-dependent pathway is bypassed in murine hematopoietic malignancies Genes & Development  1998 12:2475-2487  DOI:10.1101/gad.12.16.2475  PMID:9716401  PMCID:PMC317092